isoxazoles has been researched along with Cancer of Colon in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (29.63) | 18.7374 |
| 1990's | 1 (3.70) | 18.2507 |
| 2000's | 5 (18.52) | 29.6817 |
| 2010's | 11 (40.74) | 24.3611 |
| 2020's | 2 (7.41) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, WL; Chen, CH; Liu, YW; Lu, FJ; Peng, JY; Wong, CH | 1 |
| Czerski, A; Czyżnikowska, Ż; Jęśkowiak, I; Mączyński, M; Regiec, A; Sochacka-Ćwikła, A; Wiatrak, B | 1 |
| Hattori, Y; Imura, J; Ohashi, W; Yamamine, N | 1 |
| Croft, A; Guo, ST; Jiang, CC; Jin, L; Wang, CY; Yan, XG; Zhang, XD | 1 |
| Al-Abed, Y; Birmpilis, AI; Cheng, KF; Crichlow, GV; Ioannou, K; Lolis, EJ; Tsitsilonis, OE | 1 |
| Deckert, S; Djuzenova, CS; Fiedler, V; Flentje, M; Katzer, A; Michel, K; Sukhorukov, VL; Zimmermann, H | 1 |
| Banerjee, S; Gok, S; Inan Genç, A; Severcan, F | 1 |
| Farrelly, M; Guo, ST; Jiang, CC; Jin, L; La, T; Lei, FX; Liu, F; Wang, CY; Wang, JY; Yan, XG; Yari, H; Zhang, XD; Zhang, YY | 1 |
| Majumdar, DK; Ray, AR; Thakral, NK | 1 |
| Dervenis, C; Kapota, E; Kostopanagiotou, G; Matsota, P; Pandazi, A; Paraskevopoulou, P | 1 |
| Chen, B; Huang, WH; Lee, AR; Media, J; Shaw, J; Valeriote, FA | 1 |
| Bar-Shalom, D; Eriksson, AH; Majumdar, DK; Ray, AR; Thakral, NK | 1 |
| Peng, Z; Raufman, JP; Xie, G | 1 |
| Mall, JW; Myers, JA; Philipp, AW; Pollmann, C; Saclarides, TJ; Xu, X | 1 |
| Bleichrodt, RP; Boerman, OC; Goldenberg, DM; Hendriks, T; Koppe, MJ; Oyen, WJ; Verhofstad, AA | 1 |
| Kitamura, T; Matsuura, M; Mutoh, M; Niho, N; Sato, H; Sugimura, T; Takahashi, M; Wakabayashi, K | 1 |
| Isoe, T; Miura, T; Nakamura, K; Shibuya, M; Taguchi, E | 1 |
| Han, M; Im, DS; Jo, JY; Kim, HL; Kim, K; Kim, YL; Lee, YK; Sacket, SJ | 1 |
| Arakawa, M; Ardalan, B; Cooney, DA; Jayaram, H; Villacorte, D | 1 |
| Cripps, C; Eisenhauer, E; Fields, AL; Maroun, JA; Pater, JL; Stewart, DJ | 1 |
| Bittner, G; Fischer, PH; Pamukcu, R; Willson, JK | 1 |
| Bakker, CT; Jansen, PL; Oude Elferink, RP | 1 |
| Huber, KR; Roberts, J; Rosenfeld, H | 1 |
| Eisenhauer, EA; Fields, AL; Maroun, JA; Walde, PL | 1 |
| Huber, KR; Mayer, EP; Mitchell, DF; Roberts, J | 1 |
| Adolphson, CC; Ajani, JA; Barlogie, B; Bedikian, AY; Bodey, GP; Korinek, J; Stroehlein, JR | 1 |
| Aoki, T; Eble, JN; Glover, JL; Sebolt, JS; Weber, G | 1 |
1 trial(s) available for isoxazoles and Cancer of Colon
| Article | Year |
|---|---|
Preincisional versus postincisional administration of parecoxib in colorectal surgery: effect on postoperative pain control and cytokine response. A randomized clinical trial.
Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Colectomy; Colonic Neoplasms; Cyclooxygenase 2 Inhibitors; Cytokines; Double-Blind Method; Female; Humans; Isoxazoles; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative | 2010 |
26 other study(ies) available for isoxazoles and Cancer of Colon
| Article | Year |
|---|---|
Parecoxib expresses anti-metastasis effect through inhibition of epithelial-mesenchymal transition and the Wnt/β-catenin signaling pathway in human colon cancer DLD-1 cell line.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; beta Catenin; Cadherins; Cell Line; Cell Line, Tumor; Cell Movement; Colonic Neoplasms; Cyclooxygenase 2; Epithelial-Mesenchymal Transition; Glycogen Synthase Kinase 3 beta; Humans; Isoxazoles; Proto-Oncogene Proteins c-akt; Vimentin; Wnt Signaling Pathway | 2022 |
New Oxazolo[5,4-
Topics: Adenocarcinoma; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Cell Proliferation; Cisplatin; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Isoxazoles; Molecular Docking Simulation; Molecular Structure; Purines; Pyrimidines; Structure-Activity Relationship; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2022 |
SKL2001 suppresses colon cancer spheroid growth through regulation of the E-cadherin/β-Catenin complex.
Topics: Antigens, CD; Antineoplastic Agents; beta Catenin; Cadherins; Cell Cycle Checkpoints; Colonic Neoplasms; HCT116 Cells; Humans; Imidazoles; Isoxazoles; Spheroids, Cellular; Tumor Cells, Cultured; Tumor Microenvironment | 2017 |
BAG3-dependent expression of Mcl-1 confers resistance of mutant KRAS colon cancer cells to the HSP90 inhibitor AUY922.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Colonic Neoplasms; Drug Resistance, Neoplasm; Endoplasmic Reticulum Stress; Gene Expression Regulation, Neoplastic; Heat Shock Transcription Factors; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins p21(ras); Resorcinols | 2018 |
ISO-66, a novel inhibitor of macrophage migration, shows efficacy in melanoma and colon cancer models.
Topics: Animals; Antineoplastic Agents; Catalytic Domain; Colonic Neoplasms; Female; Gene Expression Regulation, Neoplastic; Isoxazoles; Macrophage Migration-Inhibitory Factors; Melanoma; Mice; Mice, Nude; Neoplasms, Experimental; Phenols; Small Molecule Libraries; Spleen | 2014 |
Dual PI3K- and mTOR-inhibitor PI-103 can either enhance or reduce the radiosensitizing effect of the Hsp90 inhibitor NVP-AUY922 in tumor cells: The role of drug-irradiation schedule.
Topics: Cell Cycle Checkpoints; Cell Line, Tumor; Colonic Neoplasms; DNA Damage; Drug Administration Schedule; Drug Synergism; Furans; Glioblastoma; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; Phosphoinositide-3 Kinase Inhibitors; Pyridines; Pyrimidines; Radiation Tolerance; Radiation-Sensitizing Agents; Resorcinols; TOR Serine-Threonine Kinases; Up-Regulation | 2016 |
Valdecoxib Recovers the Lipid Composition, Order and Dynamics in Colon Cancer Cell Lines Independent of COX-2 Expression: An ATR-FTIR Spectroscopy Study.
Topics: Alkenes; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cluster Analysis; Colonic Neoplasms; Cyclooxygenase 2 Inhibitors; HT29 Cells; Humans; Isoxazoles; Spectroscopy, Fourier Transform Infrared; Sulfonamides | 2017 |
Reactivation of ERK and Akt confers resistance of mutant BRAF colon cancer cells to the HSP90 inhibitor AUY922.
Topics: Apoptosis; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Chaperonins; Colonic Neoplasms; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; Mutation; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Resorcinols; Xenograft Model Antitumor Assays | 2016 |
Eudragit S-100 entrapped chitosan microspheres of valdecoxib for colon cancer.
Topics: Colonic Neoplasms; Cyclooxygenase 2 Inhibitors; Humans; Isoxazoles; Microspheres; Polymethacrylic Acids; Sulfonamides | 2010 |
The small-molecule TNF-alpha modulator, UTL-5g, reduces side effects induced by cisplatin and enhances the therapeutic effect of cisplatin in vivo.
Topics: Animals; Antineoplastic Agents; Blood Urea Nitrogen; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Cisplatin; Colonic Neoplasms; Female; Hematologic Diseases; Humans; Isoxazoles; Kidney Diseases; Lethal Dose 50; Male; Mice; Mice, Inbred ICR; Mice, SCID; Platelet Count; Toxicity Tests, Acute; Tumor Necrosis Factor-alpha | 2011 |
The quest for targeted delivery in colon cancer: mucoadhesive valdecoxib microspheres.
Topics: Alginates; Analysis of Variance; Animals; Antineoplastic Agents; Biological Transport; Caco-2 Cells; Calorimetry, Differential Scanning; Colonic Neoplasms; Cyclooxygenase 2 Inhibitors; Drug Delivery Systems; Drug Stability; Glucuronic Acid; Goats; Hexuronic Acids; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestine, Large; Isoxazoles; Microscopy, Electron, Scanning; Microspheres; Oxidoreductases; Particle Size; Polymethacrylic Acids; Spectroscopy, Fourier Transform Infrared; Sulfonamides; X-Ray Diffraction | 2011 |
Src-mediated cross-talk between farnesoid X and epidermal growth factor receptors inhibits human intestinal cell proliferation and tumorigenesis.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Colonic Neoplasms; Epithelial Cells; ErbB Receptors; Gene Expression; Gene Knockdown Techniques; Humans; Intestinal Mucosa; Isoxazoles; Mice; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Pregnenediones; Receptors, Cytoplasmic and Nuclear; RNA Interference; Signal Transduction; src-Family Kinases; Transplantation, Heterologous | 2012 |
[Leflunomide reduces the angiogenesis score and tumor growth of subcutaneously implanted colon carcinoma cells in the mouse model].
Topics: Administration, Oral; Animals; Capillaries; Cell Division; Colonic Neoplasms; HT29 Cells; Humans; Injections, Intraperitoneal; Isoxazoles; Leflunomide; Mice; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Random Allocation; Uridine | 2002 |
Combination therapy using the cyclooxygenase-2 inhibitor Parecoxib and radioimmunotherapy in nude mice with small peritoneal metastases of colonic origin.
Topics: Animals; Antibodies, Monoclonal; Carcinoma; Colonic Neoplasms; Cyclooxygenase Inhibitors; Iodine Radioisotopes; Isoxazoles; Male; Maximum Tolerated Dose; Mice; Mice, Inbred BALB C; Mice, Nude; Peritoneal Neoplasms; Radioimmunotherapy; Survival; Tissue Distribution; Transplantation, Heterologous | 2006 |
Suppression of azoxymethane-induced colon cancer development in rats by a cyclooxygenase-1 selective inhibitor, mofezolac.
Topics: Animals; Azoxymethane; Carcinoma; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Isoxazoles; Male; Membrane Proteins; Rats; Rats, Inbred F344 | 2006 |
Anti-tumor activity and tumor vessel normalization by the vascular endothelial growth factor receptor tyrosine kinase inhibitor KRN951 in a rat peritoneal disseminated tumor model.
Topics: Animals; Antineoplastic Agents; Ascites; Cell Line, Tumor; Colonic Neoplasms; Disease Models, Animal; Humans; Isoxazoles; Neovascularization, Pathologic; Peritoneal Neoplasms; Phenylurea Compounds; Phosphorylation; Protein Kinase Inhibitors; Rats; Rats, Inbred F344; Receptors, Vascular Endothelial Growth Factor | 2008 |
Lysophosphatidylserine induces calcium signaling through Ki16425/VPC32183-sensitive GPCR in bone marrow-derived mast cells and in C6 glioma and colon cancer cells.
Topics: Animals; Bone Marrow Cells; Calcium Signaling; Colonic Neoplasms; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; Glioma; HCT116 Cells; Humans; Inositol 1,4,5-Trisphosphate Receptors; Isoxazoles; Lysophospholipids; Male; Mast Cells; Mice; Mice, Inbred BALB C; Organophosphates; Pertussis Toxin; Propionates; Pyridines; Pyrrolidinones; Rats; Receptors, Lysophosphatidic Acid; Time Factors; Type C Phospholipases | 2008 |
Effect of L-glutamine antagonists on 5-phosphoribosyl 1-pyrophosphate levels in P388 leukemia and in murine colon adenocarcinomas in vivo.
Topics: Adenocarcinoma; Animals; Azaserine; Colonic Neoplasms; Diazooxonorleucine; Glutamine; Intestine, Small; Isoxazoles; Leukemia P388; Leukemia, Experimental; Mice; Neoplasms, Experimental; Pentosephosphates; Phosphoribosyl Pyrophosphate | 1982 |
Phase II study of acivicin in colorectal carcinoma: a National Cancer Institute of Canada study.
Topics: Adenocarcinoma; Adult; Aged; Antibiotics, Antineoplastic; Central Nervous System Diseases; Colonic Neoplasms; Drug Administration Schedule; Drug Evaluation; Female; Hematologic Diseases; Humans; Infusions, Parenteral; Isoxazoles; Male; Middle Aged; Oxazoles; Rectal Neoplasms | 1984 |
Enhancement of the sensitivity of human colon cancer cells to growth inhibition by acivicin achieved through inhibition of nucleic acid precursor salvage by dipyridamole.
Topics: Antibiotics, Antineoplastic; Cell Cycle; Cell Line; Cell Survival; Colonic Neoplasms; Dipyridamole; Humans; Isoxazoles; Kinetics; Oxazoles; Ribonucleosides; Ribonucleotides | 1984 |
Glutathione-conjugate transport by human colon adenocarcinoma cells (Caco-2 cells).
Topics: Adenocarcinoma; Adenosine Triphosphate; Biological Transport, Active; Chromatography, High Pressure Liquid; Colonic Neoplasms; Dinitrochlorobenzene; Dinitrophenols; gamma-Glutamyltransferase; Glutathione; Glutathione Transferase; Humans; Isoxazoles; Tumor Cells, Cultured | 1993 |
Uptake of glutamine antimetabolites 6-diazo-5-oxo-L-norleucine (DON) and acivicin in sensitive and resistant tumor cell lines.
Topics: Animals; Antibiotics, Antineoplastic; Antimetabolites; Azo Compounds; Biological Transport; Colonic Neoplasms; Diazooxonorleucine; Drug Resistance; Glutamine; Humans; Isoxazoles; Kinetics; Leukemia P388; Lung Neoplasms; Mice; Neoplasms, Experimental; Oxazoles; Tumor Cells, Cultured | 1988 |
Phase II study of acivicin as a 72-hr continuous infusion in patients with untreated colorectal cancer. A National Cancer Institute of Canada Clinical Trials Group Study.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Canada; Colonic Neoplasms; Drug Evaluation; Female; Humans; Infusions, Intravenous; Isoxazoles; Male; Middle Aged; Oxazoles; Rectal Neoplasms | 1987 |
Cell cycle phase perturbations by 6-diazo-5-oxo-L-norleucine and acivicin in normal and neoplastic human cell lines.
Topics: Antimetabolites; Azo Compounds; Cell Cycle; Cell Line; Colonic Neoplasms; Diazooxonorleucine; Drug Evaluation, Preclinical; Glutaminase; Glutamine; Humans; Isoxazoles; Lung Neoplasms; Neoplasms, Experimental; Oxazoles | 1987 |
Phase II trial of acivicin in patients with advanced colorectal carcinoma.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Colonic Neoplasms; Drug Evaluation; Female; Humans; Isoxazoles; Leukopenia; Male; Middle Aged; Nausea; Neoplasm Metastasis; Oxazoles; Rectal Neoplasms; Vomiting | 1986 |
Inactivation by acivicin of carbamoyl-phosphate synthetase II of human colon carcinoma.
Topics: Antibiotics, Antineoplastic; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Colon; Colonic Neoplasms; Glutamine; Humans; Isoxazoles; Kinetics; Ligases; Oxazoles | 1985 |