isoxazoles has been researched along with Bone Neoplasms in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 7 (63.64) | 24.3611 |
| 2020's | 2 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Gaivão, I; Lemos, S; Ludovico, P; Martins, G; Oliveira, P; Palmeira, C; Peixoto, F; Pinto-Leite, R; Sampaio-Marques, B | 1 |
| Gunosewoyo, H; Jia, KH; Luo, J; Shi, JJ; Sun, H; Tang, J; Yang, F; Yu, LF | 1 |
| Chen, J; Cong, X; Zhan, X; Zheng, W; Zhou, Z | 1 |
| Bui, MM; Chu, B; Fu, W; Ma, L; Pledger, WJ; Reed, D; Sharma, SS | 1 |
| Bhagat, S; Fullerton, SL; Kenner, DJ | 1 |
| Ballazhi, L; Ibrahimi, I; Imeri, F; Jashari, A; Mikhova, B; Mladenovska, K; Popovski, E | 1 |
| Lin, W; Liu, BL; Pan, HL; Zhang, YQ | 1 |
| Massey, AJ | 1 |
| Chen, XL; Guo, C; Huang, JL; Wang, YX | 1 |
| Bevan, S; Courade, JP; Dawson, J; Fox, A; Glatt, M; Gonzalez, I; Medhurst, S; Urban, L | 1 |
| Bordet, JC; Boucharaba, A; Clézardin, P; Guglielmi, J; Peyruchaud, O; Serre, CM | 1 |
11 other study(ies) available for isoxazoles and Bone Neoplasms
| Article | Year |
|---|---|
Elucidating the mechanisms of action of parecoxib in the MG-63 osteosarcoma cell line.
Topics: Apoptosis; Bone Neoplasms; Cell Cycle; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Humans; Isoxazoles; Osteosarcoma; Tumor Cells, Cultured | 2020 |
Synthesis and Pharmacological Evaluation of σ2 Receptor Ligands Based on a 3-Alkoxyisoxazole Scaffold: Potential Antitumor Effects against Osteosarcoma.
Topics: Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Isoxazoles; Ligands; Molecular Structure; Osteosarcoma; Receptors, sigma; Structure-Activity Relationship; Tumor Cells, Cultured | 2021 |
Effects of Parecoxib on Pain Threshold and Inflammatory Factors IL-1β, IL-6 and TNF-
Topics: Animals; Bone Neoplasms; Cancer Pain; Cyclooxygenase 2 Inhibitors; Down-Regulation; Female; Hyperalgesia; Inflammation; Interleukin-1beta; Interleukin-6; Isoxazoles; Pain Threshold; Random Allocation; Rats; Rats, Sprague-Dawley; Spinal Cord; Tumor Necrosis Factor-alpha | 2019 |
Apoptosis of osteosarcoma cultures by the combination of the cyclin-dependent kinase inhibitor SCH727965 and a heat shock protein 90 inhibitor.
Topics: Apoptosis; bcl-2-Associated X Protein; Bone Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle; Cell Line, Tumor; Cyclic N-Oxides; Cyclin-Dependent Kinases; Cytosol; Drug Synergism; Gene Expression Regulation, Neoplastic; HSP90 Heat-Shock Proteins; Humans; Indolizines; Isoxazoles; Mitochondria; Osteosarcoma; Protein Kinase Inhibitors; Protein Transport; Pyridinium Compounds; Resorcinols; Signal Transduction | 2013 |
Daily subcutaneous parecoxib injection for cancer pain: an open label pilot study.
Topics: Analgesics, Opioid; Analysis of Variance; Bone Neoplasms; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Female; Hospital Units; Humans; Injections, Subcutaneous; Isoxazoles; Male; Neoplasm Metastasis; Pain Management; Pain Measurement; Palliative Care; Pilot Projects; Treatment Outcome; Victoria | 2015 |
Potential antiproliferative effect of isoxazolo- and thiazolo coumarin derivatives on breast cancer mediated bone and lung metastases.
Topics: 4-Hydroxycoumarins; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Coumarins; Dose-Response Relationship, Drug; Female; Humans; Inhibitory Concentration 50; Isoxazoles; Lung Neoplasms; Thiazoles; Time Factors | 2015 |
Modulation of Nav1.8 by Lysophosphatidic Acid in the Induction of Bone Cancer Pain.
Topics: Animals; Biophysics; Bone Neoplasms; Cancer Pain; Carcinoma; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Female; Ganglia, Spinal; Gene Expression Regulation, Neoplastic; Hyperalgesia; Isoxazoles; Lysophospholipids; Membrane Potentials; NAV1.8 Voltage-Gated Sodium Channel; Neurons; Pain Measurement; Patch-Clamp Techniques; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Lysophosphatidic Acid | 2016 |
Inhibition of ATR-dependent feedback activation of Chk1 sensitises cancer cells to Chk1 inhibitor monotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Bone Neoplasms; Cell Proliferation; Checkpoint Kinase 1; Colorectal Neoplasms; DNA Damage; DNA-Activated Protein Kinase; Dose-Response Relationship, Drug; Histones; HT29 Cells; Humans; Indoles; Isoxazoles; Molecular Targeted Therapy; Nuclear Proteins; Osteosarcoma; Protein Kinase Inhibitors; Pyrazines; Pyridones; Signal Transduction; Time Factors | 2016 |
Contributions of spinal D-amino acid oxidase to bone cancer pain.
Topics: Analgesia; Analgesics, Opioid; Animals; Astrocytes; Bone Neoplasms; Carcinoma 256, Walker; D-Amino-Acid Oxidase; Enzyme Inhibitors; Female; Gene Expression; Hyperalgesia; Injections, Spinal; Isoxazoles; Morphine; Nerve Tissue Proteins; Pain; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Opioid, mu; Spinal Cord; Tibia | 2012 |
Anti-hyperalgesic activity of the cox-2 inhibitor lumiracoxib in a model of bone cancer pain in the rat.
Topics: Analysis of Variance; Animals; Behavior, Animal; Bone Density; Bone Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Freund's Adjuvant; Hyperalgesia; Inflammation; Isoenzymes; Isoxazoles; Organic Chemicals; Pain; Pain Measurement; Prostaglandin-Endoperoxide Synthases; Radiology; Rats; Rats, Sprague-Dawley; Sulfonamides; Time Factors; Tumor Cells, Cultured | 2004 |
The type 1 lysophosphatidic acid receptor is a target for therapy in bone metastases.
Topics: Animals; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Cytokines; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; Isoxazoles; Lysophospholipids; Mice; Neoplasm Metastasis; Osteoclasts; Propionates; Receptors, Lysophosphatidic Acid | 2006 |