isoxazoles has been researched along with Bone Loss, Osteoclastic in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Cai, C; Chu, T; Dong, S; Hu, W; Kang, F; Li, Y | 1 |
| Bonnelye, E; Chun, J; Clézardin, P; David, M; Holen, I; Ishii, M; Jurdic, P; Kikuta, J; Leblanc, R; Machuca-Gayet, I; Mima, F; Ottewell, P; Peyruchaud, O; Ribeiro, J; Vales, RL | 1 |
| Caeiro, JR; Conde, C; Gómez-Reino, JJ; González, A; Guede, D; Martínez, P; Orosa, B | 1 |
| Fujikawa, Y; Itonaga, I; Kawashima, M; Takita, C; Tsumura, H | 1 |
| Li, Z; Liu, M; Liu, T; Luo, J; Qiu, WW; Tang, J; Xu, J; Yang, F | 1 |
| Hibi, T; Ikeda, K; Ikeda, Y; Ishizuka, Y; Kawahara, M; Kondo, T; Niida, S; Suzuki, Y; Taniguchi, N | 1 |
| Arai, Y; Hakeda, Y; Kaneda, T; Kobayashi, Y; Kumegawa, M; Sato, T; Shin, K; Ueyama, S; Yoshida, Y | 1 |
| Brazier, M; Clayssens, S; Daragon, A; Jouen, F; Klemmer, N; Le Loët, X; Lequerré, T; Mejjad, O; Ménard, JF; Tron, F; Vittecoq, O | 1 |
8 other study(ies) available for isoxazoles and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
Farnesoid X receptor agonist attenuates subchondral bone osteoclast fusion and osteochondral pathologies of osteoarthritis via suppressing JNK1/2/NFATc1 pathway.
Topics: Animals; Bone Remodeling; Bone Resorption; Female; Gene Expression Regulation; Isoxazoles; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; NFATC Transcription Factors; Osteoarthritis; Osteoclasts; Osteogenesis; RNA-Binding Proteins | 2022 |
Lysophosphatidic acid receptor type 1 (LPA1) plays a functional role in osteoclast differentiation and bone resorption activity.
Topics: Animals; Bone Marrow Cells; Bone Resorption; Cell Differentiation; Cell Movement; Female; Isoxazoles; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Knockout; Nerve Tissue Proteins; NFATC Transcription Factors; Oleic Acids; Organophosphates; Osteoclasts; Propionates; Receptors, Lysophosphatidic Acid | 2014 |
Effect of lysophosphatidic acid receptor inhibition on bone changes in ovariectomized mice.
Topics: Animals; Bone and Bones; Bone Remodeling; Bone Resorption; Calcification, Physiologic; Cell Differentiation; Disease Models, Animal; Female; Femur; Humans; Immunoenzyme Techniques; Isoxazoles; Lysophospholipids; Mice; Mice, Inbred C57BL; Osteoblasts; Osteoclasts; Osteoporosis; Osteoporosis, Postmenopausal; Ovariectomy; Propionates; Receptors, Lysophosphatidic Acid; Signal Transduction; X-Ray Microtomography | 2015 |
The effect of selective cyclooxygenase-2 inhibitor on human osteoclast precursors to influence osteoclastogenesis in vitro.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Bone Resorption; Celecoxib; Cell Growth Processes; Cell Survival; Cells, Cultured; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Humans; Indomethacin; Isoxazoles; Macrophage Colony-Stimulating Factor; Osteoclasts; Pyrazoles; RANK Ligand; Stem Cells; Sulfonamides; Time Factors | 2009 |
Synthesis and biological evaluation of heterocyclic ring-fused betulinic acid derivatives as novel inhibitors of osteoclast differentiation and bone resorption.
Topics: Acid Phosphatase; Animals; Betulinic Acid; Bone Density Conservation Agents; Bone Resorption; Cathepsin K; Cell Differentiation; Cell Line; Cell Proliferation; Crystallography, X-Ray; Female; Isoenzymes; Isoxazoles; Mice; Mice, Inbred C57BL; Osteoclasts; Ovariectomy; Pentacyclic Triterpenes; Pyrazines; Pyrazoles; Pyrimidines; RANK Ligand; Rats; Structure-Activity Relationship; Tartrate-Resistant Acid Phosphatase; Thiazoles; Triterpenes | 2012 |
Gamma-glutamyltranspeptidase stimulates receptor activator of nuclear factor-kappaB ligand expression independent of its enzymatic activity and serves as a pathological bone-resorbing factor.
Topics: Animals; Bone Marrow Cells; Bone Resorption; Calcitonin; Carrier Proteins; Cell Line, Tumor; Cells, Cultured; Cloning, Molecular; DNA, Complementary; Dose-Response Relationship, Drug; gamma-Glutamyltransferase; Glutathione; Immunoblotting; Isoxazoles; Ligands; Membrane Glycoproteins; Mice; Mice, Inbred C3H; Molecular Sequence Data; Oocytes; Osteoclasts; Protein Binding; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Xenopus | 2004 |
The active metabolite of leflunomide, A771726, inhibits both the generation of and the bone-resorbing activity of osteoclasts by acting directly on cells of the osteoclast lineage.
Topics: Aniline Compounds; Animals; Binding Sites; Bone Resorption; Carrier Proteins; Cell Differentiation; Cell Lineage; Cells, Cultured; Crotonates; Electrophoretic Mobility Shift Assay; Hydroxybutyrates; Isoxazoles; Leflunomide; Membrane Glycoproteins; Mice; NF-kappa B; Nitriles; Osteoclasts; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins pp60(c-src); Pyrimidines; Rabbits; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Toluidines | 2004 |
Autoantibodies, metalloproteinases and bone markers in rheumatoid arthritis patients are unable to predict their responses to infliximab.
Topics: Adult; Aged; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Autoantibodies; Biomarkers; Bone Resorption; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Female; Humans; Infliximab; Isoxazoles; Leflunomide; Male; Metalloproteases; Methotrexate; Middle Aged; Prognosis; Prospective Studies; Rheumatoid Factor; Tumor Necrosis Factor-alpha | 2007 |