isoxazoles has been researched along with Autoimmune Diabetes in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (53.33) | 18.2507 |
| 2000's | 5 (33.33) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anderson, RM; Benjamin, C; Benninger, KS; Chopra, G; Conteh, AM; Fine, J; Hernandez-Perez, M; Linnemann, AK; Maloney, DJ; Mirmira, RG; Nadler, JL; Nelson, JB; Tersey, SA | 1 |
| Chang, DM; Chien, MW; Fu, SH; Hsu, CY; Liu, YW; Miaw, SC; Sytwu, HK; Yeh, LT | 1 |
| Berges, W; Donner, P; Gugenberger, C; Naami, A | 1 |
| Ekberg, H; Qi, Z; Shan, S; Wu, D; Zhang, L | 1 |
| Al-Abed, Y; Bacher, M; Cvetkovic, I; Lan, HY; Maksimovic-Ivanic, D; Miljkovic, D; Nicoletti, F; Roth, J; Stosic-Grujicic, S | 1 |
| Osborne, TF; Shin, DJ | 1 |
| Duguid, WP; Marliss, EB; Misra, M | 1 |
| Bartlett, RR; Dimitrijević, M; Stosić-Grujicić, S | 2 |
| Chong, AS; Foster, P; Guo, Z; Jensik, S; McChesney, L; Mital, D; Sankary, H; Shen, J; Tian, Y; Williams, JW; Yin, D | 1 |
| Chong, AS; Foster, PF; Fu, Z; Guo, Z; Jensik, S; McChesney, LP; Mital, D; Sankary, HN; Shen, J; Tian, Y; Williams, JW | 1 |
| Chong, AS; Foster, P; Guo, Z; Jensik, SC; McChesney, L; Mital, D; Sankary, H; Shen, J; Tian, Y; Williams, JW | 1 |
| Bartlett, R; Dimitrijevic, M; Stosic-Grujicic, S | 1 |
| Bartlett, RR; Kurrle, R; Schleyerbach, R; Schorlemmer, HU | 1 |
| Bouillon, R; Gysemans, C; Laureys, J; Mathieu, C; Waer, M | 1 |
15 other study(ies) available for isoxazoles and Autoimmune Diabetes
| Article | Year |
|---|---|
Inhibition of 12/15-Lipoxygenase Protects Against β-Cell Oxidative Stress and Glycemic Deterioration in Mouse Models of Type 1 Diabetes.
Topics: Animals; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Blood Glucose; Cells, Cultured; Computer Simulation; Diabetes Mellitus, Type 1; Female; Humans; Hydroxyquinolines; Insulin-Secreting Cells; Isoxazoles; Lipoxygenase Inhibitors; Mice; Mice, Inbred NOD; Molecular Structure; Naphthalenes; Oxidative Stress; Protein Binding; Software; Thiophenes | 2017 |
SUMO-defective c-Maf preferentially transactivates Il21 to exacerbate autoimmune diabetes.
Topics: Amino Acid Substitution; Animals; Benzimidazoles; Binding Sites; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Diabetes Mellitus, Type 1; Epigenesis, Genetic; Interleukins; Isoxazoles; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Knockout; Mice, SCID; Mice, Transgenic; Models, Biological; Mutant Proteins; p300-CBP Transcription Factors; Promoter Regions, Genetic; Proto-Oncogene Proteins c-maf; Sumoylation; Transcriptional Activation | 2018 |
[Persistent diarrhea and loss of weight during therapy with leflunomide].
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Colitis, Lymphocytic; Diabetes Mellitus, Type 1; Diarrhea; Female; Hashimoto Disease; Humans; Hypertension; Isoxazoles; Leflunomide; Middle Aged; Weight Loss | 2008 |
Additive effects of leflunomide and tacrolimus in prevention of islet xenograft rejection.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drug Synergism; Graft Rejection; Histocytochemistry; Immunosuppressive Agents; Interleukin-2; Islets of Langerhans Transplantation; Isoxazoles; Leflunomide; Lymphocyte Subsets; Male; Mice; Mice, Inbred BALB C; Rats; Rats, Wistar; T-Lymphocytes; Tacrolimus; Transplantation, Heterologous | 2004 |
Critical role of macrophage migration inhibitory factor activity in experimental autoimmune diabetes.
Topics: Animals; Antibodies; CD11b Antigen; Cell Adhesion; Cell Proliferation; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Isoxazoles; Macrophage Migration-Inhibitory Factors; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Monocytes; Nitric Oxide; Receptors, Interleukin-2; Spleen | 2005 |
Peroxisome proliferator-activated receptor-gamma coactivator-1alpha activation of CYP7A1 during food restriction and diabetes is still inhibited by small heterodimer partner.
Topics: Animals; Bile Acids and Salts; Carrier Proteins; Cell Line; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Diabetes Mellitus, Type 1; DNA-Binding Proteins; Enzyme Induction; Fasting; Heat-Shock Proteins; Homeostasis; Humans; Isoxazoles; Liver; Male; Mice; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Promoter Regions, Genetic; Protein Structure, Tertiary; Receptors, Cytoplasmic and Nuclear; RNA Interference; RNA-Binding Proteins; Trans-Activators; Transcription Factors; Transcriptional Activation | 2008 |
Prevention of diabetes in the spontaneously diabetic BB rat by the glutamine antimetabolite acivicin.
Topics: Animals; Blood Cell Count; Diabetes Mellitus, Type 1; Drug Interactions; Enzyme Inhibitors; Female; gamma-Glutamyltransferase; Glucose Tolerance Test; Glutamic Acid; Glutamine; Ionomycin; Isoxazoles; Lymphocyte Subsets; Male; Rats; Rats, Inbred BB; Spleen; Tetradecanoylphorbol Acetate | 1996 |
A novel immunomodulating agent--leflunomide inhibits experimental autoimmune diabetes in mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Hyperglycemia; Immunosuppressive Agents; Isoxazoles; Leflunomide; Male; Mice; Mice, Inbred CBA; Time Factors | 1996 |
Effect of leflunomide and cyclosporine on concordant xenogeneic islet transplantation in streptozotocin-induced and autoimmune diabetic mice.
Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Graft Survival; Immunosuppressive Agents; Islets of Langerhans Transplantation; Isoxazoles; Leflunomide; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Rats; Rats, Sprague-Dawley; Species Specificity; Transplantation, Heterologous | 1997 |
Successful xenotransplantation of adult porcine islets in NOD and BALB/c mice with leflunomide and cyclosporine.
Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Graft Survival; Immunosuppressive Agents; Isoxazoles; Leflunomide; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Swine; Transplantation, Heterologous | 1997 |
Differential effect of leflunomide on concordant xenogeneic islet graft rejection and recurrence of autoimmune diabetes.
Topics: Animals; Autoimmunity; Diabetes Mellitus, Type 1; Graft Rejection; Immunosuppressive Agents; Islets of Langerhans Transplantation; Isoxazoles; Leflunomide; Mice; Mice, Inbred NOD; Rats; Rats, Sprague-Dawley; Recurrence; Transplantation, Heterologous | 1998 |
Prevention of experimental autoimmune diabetes in mice by treatment with leflunomide.
Topics: Aniline Compounds; Animals; Crotonates; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Fibrosis; Hydroxybutyrates; Immunosuppressive Agents; Islets of Langerhans; Isoxazoles; Leflunomide; Male; Mice; Mice, Inbred CBA; Nitriles; Toluidines | 1998 |
Leflunomide protects mice from multiple low dose streptozotocin (MLD-SZ)-induced insulitis and diabetes.
Topics: Animals; Autoimmune Diseases; Blood Glucose; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Immunosuppressive Agents; Interferon-gamma; Islets of Langerhans; Isoxazoles; Leflunomide; Male; Mice; Mice, Inbred CBA; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pancreatitis; Streptozocin; T-Lymphocytes, Cytotoxic | 1999 |
Generation of O2- radicals in macrophages can be inhibited in vitro and in vivo by derivatives of leflunomide's primary metabolite.
Topics: Acrylamides; Alkynes; Animals; Caproates; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Free Radicals; Humans; Immunosuppressive Agents; Isoxazoles; Macrophages; Mice; Mice, Inbred NOD; Nitriles; Superoxides | 1999 |
Leflunomide and its analogue X920715 synergize with cyclosporin A in preventing early graft failure and delaying graft rejection of xenogeneic islets in nonobese diabetic mice.
Topics: Alkynes; Animals; Cyclosporine; Diabetes Mellitus, Type 1; Drug Synergism; Graft Rejection; Immunosuppressive Agents; Islets of Langerhans Transplantation; Isoxazoles; Leflunomide; Mice; Mice, Inbred NOD; Nitriles; Rats; Transplantation, Heterologous | 2001 |