isoxazoles has been researched along with Allergic Encephalomyelitis in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 6 (54.55) | 24.3611 |
| 2020's | 2 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Bahn, YS; Cheong, E; Choi, JW; Hwang, H; Kim, B; Kim, HJ; Kim, J; Kim, JW; Kim, R; Kim, S; Kim, Y; Lee, EH; Lee, HY; Lee, J; Park, JH; Park, KD; Park, SJ; Seo, SH; Yeon, SK | 1 |
| Akassoglou, K; Ang, KK; Arkin, MR; Baeten, KM; Bardehle, S; Bedard, C; Bruneau, BG; Green, AJ; Hanspers, K; Jiang, X; Machado, MR; Mendiola, AS; Merlini, M; Meyer-Franke, A; Meza-Acevedo, R; Petersen, MA; Pfaff, SJ; Pico, AR; Pleiss, MA; Rafalski, VA; Rios Coronado, PE; Ryu, JK; Thomas, R; Thomas, S; Tognatta, R; Wang, J; Williams, A; Wilson, C; Yan, Z; Zamvil, SS | 1 |
| Bol, JGJM; Brevé, JJP; Chrobok, NL; Drukarch, B; El Alaoui, S; Jongenelen, CA; van Dam, AM; Wilhelmus, MMM | 1 |
| Al-Abed, Y; Bramanti, A; Bramati, P; Cavalli, E; Fagone, P; Mangano, K; Mazzon, E; Nicoletti, F; Petralia, MC | 1 |
| Bertolotto, A; Finardi, A; Furlan, R; Hintermann, S; Martire, S; Montarolo, F; Perga, S; Raffaele, C | 1 |
| Bol, JGJM; Breve, JJP; Chrobok, NL; de Vries, HE; Drukarch, B; Karpuj, M; Kooij, G; Sestito, C; Steinman, L; van Buul, JD; Van Dam, AM; van der Pol, SMP; van Strien, ME; Wilhelmus, MM | 1 |
| Balimane, P; Banas, D; Barrish, JC; Carter, PH; Cornelius, G; Cvijic, ME; D'Arienzo, C; Dyckman, AJ; Gillooly, K; Guo, J; Langevine, CM; Liu, R; Marino, A; McIntyre, KW; McKinnon, M; Moquin, RV; Pitts, WJ; Rex-Rabe, S; Salter-Cid, L; Shen, DR; Shuster, DJ; Spergel, SH; Suchard, SJ; Taylor, T; Warrack, B; Watterson, SH; Xie, J; Yarde, M | 1 |
| Cox, GM; Gienapp, I; Kithcart, AP; Papenfuss, T; Pruitt, J; Satoskar, AR; Shawler, T; Short, A; Sielecki, T; Whitacre, CC | 1 |
| Jung, S; Korn, T; Magnus, T; Toyka, K | 1 |
| Bartlett, RR; Schorlemmer, HU | 2 |
11 other study(ies) available for isoxazoles and Allergic Encephalomyelitis
| Article | Year |
|---|---|
Discovery of Novel Sphingosine-1-Phosphate-1 Receptor Agonists for the Treatment of Multiple Sclerosis.
Topics: Animals; beta-Arrestins; Dogs; Drug Design; Encephalomyelitis, Autoimmune, Experimental; Heart Rate; Humans; Isoxazoles; Lymphocyte Count; Lymphocytes; Male; Mice; Multiple Sclerosis; Rats; Sphingosine-1-Phosphate Receptors; Structure-Activity Relationship; Triazoles | 2022 |
Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation.
Topics: Animals; Antioxidants; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Gene Expression Profiling; Gene Regulatory Networks; High-Throughput Screening Assays; Humans; Immunity, Innate; Isoxazoles; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Microglia; Multiple Sclerosis; Neurogenic Inflammation; Oxidative Stress; Sequence Analysis, RNA; Single-Cell Analysis | 2020 |
Characterization of Transglutaminase 2 activity inhibitors in monocytes in vitro and their effect in a mouse model for multiple sclerosis.
Topics: Animals; Anti-Inflammatory Agents; Benzamides; Cells, Cultured; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Enzyme Inhibitors; Fibronectins; GTP-Binding Proteins; Humans; Isoxazoles; Mice; Mice, Inbred C57BL; Monocytes; Multiple Sclerosis; Naphthalenes; Piperidines; Protein Binding; Protein Glutamine gamma Glutamyltransferase 2; Pyrrolidines; Quinolines; Spinal Cord; Transglutaminases | 2018 |
Contribution of the macrophage migration inhibitory factor superfamily of cytokines in the pathogenesis of preclinical and human multiple sclerosis: In silico and in vivo evidences.
Topics: Animals; Antigens, Differentiation, B-Lymphocyte; Autoantigens; Cells, Cultured; Central Nervous System; Computer Simulation; Encephalomyelitis, Autoimmune, Experimental; Female; Gene Expression Regulation; Histocompatibility Antigens Class II; Humans; Hyaluronan Receptors; Intramolecular Oxidoreductases; Isoxazoles; Macrophage Migration-Inhibitory Factors; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Immunological; Multiple Sclerosis; Myelin-Oligodendrocyte Glycoprotein; Oligodendroglia; Peptide Fragments; Receptors, CXCR4; Receptors, Interleukin-8B; RNA, Messenger; Signal Transduction; T-Lymphocytes, Helper-Inducer | 2018 |
Effects of isoxazolo-pyridinone 7e, a potent activator of the Nurr1 signaling pathway, on experimental autoimmune encephalomyelitis in mice.
Topics: Animals; Axons; Cell Count; Demyelinating Diseases; Down-Regulation; Encephalomyelitis, Autoimmune, Experimental; Female; Isoxazoles; Macrophages; Mice, Inbred C57BL; Myelin-Oligodendrocyte Glycoprotein; NF-kappa B; Nuclear Receptor Subfamily 4, Group A, Member 2; Oxazoles; Peptide Fragments; Pyrimidinones; Signal Transduction; Spinal Cord; T-Lymphocytes | 2014 |
Tissue Transglutaminase contributes to experimental multiple sclerosis pathogenesis and clinical outcome by promoting macrophage migration.
Topics: Aged; Aged, 80 and over; Animals; Cell Movement; Cerebral Cortex; Encephalomyelitis, Autoimmune, Experimental; Endothelial Cells; Female; GTP-Binding Proteins; Humans; Inflammation Mediators; Isoxazoles; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Multiple Sclerosis; Myelin Sheath; Protein Glutamine gamma Glutamyltransferase 2; Rats; RNA, Messenger; Spinal Cord; Spleen; T-Lymphocytes; Transglutaminases | 2015 |
Potent and Selective Agonists of Sphingosine 1-Phosphate 1 (S1P1): Discovery and SAR of a Novel Isoxazole Based Series.
Topics: Animals; Arthritis, Experimental; Cell Movement; Cell Proliferation; CHO Cells; Cricetinae; Cricetulus; Drug Discovery; Encephalomyelitis, Autoimmune, Experimental; Humans; Immunosuppressive Agents; Isoxazoles; Lymphatic System; Lymphocytes; Lysophospholipids; Mice; Mice, Inbred C57BL; Rats; Rats, Inbred Lew; Sphingosine; Structure-Activity Relationship; Thymus Gland | 2016 |
A small-molecule inhibitor of macrophage migration inhibitory factor for the treatment of inflammatory disease.
Topics: Animals; Anti-Inflammatory Agents; Brain; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Flow Cytometry; Gene Deletion; Gene Expression Regulation; Isoxazoles; Macrophage Migration-Inhibitory Factors; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Spinal Cord; Vascular Cell Adhesion Molecule-1 | 2010 |
Modulation of effector cell functions in experimental autoimmune encephalomyelitis by leflunomide--mechanisms independent of pyrimidine depletion.
Topics: Adoptive Transfer; Animals; Animals, Newborn; Antigens, CD; B7-2 Antigen; Cells, Cultured; Chemotaxis, Leukocyte; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Guinea Pigs; Immunosuppressive Agents; Interferon-gamma; Interleukin-10; Interleukin-2; Isoxazoles; Leflunomide; Membrane Glycoproteins; Microglia; Multiple Sclerosis; Myelin Basic Protein; Pyrimidines; Rats; Rats, Inbred Lew; STAT6 Transcription Factor; T-Lymphocytes, Helper-Inducer; Trans-Activators; Uridine | 2004 |
Malononitrilamides (MNA 279 and MNA 715) have therapeutic activity in acute and chronic relapsing experimental allergic encephalomyelitis (EAE).
Topics: Acute Disease; Alkynes; Animals; Chronic Disease; Encephalomyelitis, Autoimmune, Experimental; Immunosuppressive Agents; Isoxazoles; Kinetics; Nitriles; Rats; Rats, Inbred Lew; Recurrence | 1997 |
Therapeutic activity of malononitrilamides (MNA 279 and MNA 715) on acute and chronic, relapsing, experimental, allergic encephalomyelitis (EAE).
Topics: Acute Disease; Alkynes; Animals; Chronic Disease; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Guinea Pigs; Immunosuppressive Agents; Isoxazoles; Mice; Mice, Inbred Strains; Nitriles; Rabbits; Rats; Rats, Inbred Lew | 1997 |