isoxazoles has been researched along with Akinetic-Rigid Variant of Huntington Disease in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dvorzhak, A; Grantyn, R; Semtner, M; Wójtowicz, AM | 1 |
| Kumar, A; Mishra, J | 1 |
| Chase, TN; Denaro, A; Foster, NL; Hare, TA; Tamminga, CA | 1 |
| Cross, AJ; Waddington, JL | 1 |
| Charlton, M; Goldblatt, D; Joynt, RJ; Shoulson, I | 1 |
2 trial(s) available for isoxazoles and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
THIP treatment of Huntington's disease.
Topics: Adult; Clinical Trials as Topic; Disability Evaluation; Double-Blind Method; Female; Homovanillic Acid; Humans; Huntington Disease; Isoxazoles; Male; Middle Aged; Oxazoles | 1983 |
Huntington's disease: treatment with muscimol, a GABA-mimetic drug.
Topics: Amanita; Betaine; Clinical Trials as Topic; Double-Blind Method; Humans; Huntington Disease; Isoxazoles; Oxazoles | 1977 |
4 other study(ies) available for isoxazoles and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Cells, Cultured; Cognitive Dysfunction; Corpus Striatum; Epigenomics; Gene Expression; Gene Expression Profiling; Gene Knockdown Techniques; Histones; Humans; Huntingtin Protein; Huntington Disease; Induced Pluripotent Stem Cells; Isoxazoles; Mice; Mice, Transgenic; Nerve Tissue Proteins; Neurogenesis; Neurons; Peptides; Signal Transduction; Thiophenes | 2017 |
Reduced tonic inhibition in striatal output neurons from Huntington mice due to loss of astrocytic GABA release through GAT-3.
Topics: Animals; Anisoles; Astrocytes; Corpus Striatum; GABA Agonists; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; gamma-Aminobutyric Acid; Huntington Disease; Inhibitory Postsynaptic Potentials; Isoxazoles; Male; Mice; Mice, Transgenic; Neural Inhibition; Neurons; Nipecotic Acids; Patch-Clamp Techniques; Synaptic Transmission | 2013 |
Improvement of mitochondrial function by paliperidone attenuates quinolinic acid-induced behavioural and neurochemical alterations in rats: implications in Huntington's disease.
Topics: Acetylcholinesterase; Animals; Biogenic Amines; Body Weight; Corpus Striatum; Huntington Disease; Isoxazoles; Male; Maze Learning; Memory Disorders; Mitochondria; Movement Disorders; Neurons; Neuroprotective Agents; Oxidative Stress; Oxygen; Paliperidone Palmitate; Pyrimidines; Quinolinic Acid; Rats, Wistar | 2014 |
Therapeutic failure of GABA agonist treatment in Huntington's disease.
Topics: gamma-Aminobutyric Acid; Humans; Huntington Disease; Isoxazoles; Oxazoles | 1984 |