isoxazoles has been researched along with Aging in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (11.11) | 18.7374 |
| 1990's | 6 (22.22) | 18.2507 |
| 2000's | 10 (37.04) | 29.6817 |
| 2010's | 6 (22.22) | 24.3611 |
| 2020's | 2 (7.41) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, HC; Li, H; Li, Q; Li, Y; Ou, J; Peng, C; Tang, YC; Wu, P; Xu, N | 1 |
| Cui, R; Ji, X; Kang, Y; Shi, G; Wang, Y; Yan, H; Zhang, G; Zhang, T; Zhao, H | 1 |
| Lossius, MI; Markhus, R; Nakken, KO; Sætre, E | 1 |
| Chondrogianni, N; Fotopoulou, T; Gonos, ES; Heropoulos, GA; Kapetanou, M; Koufaki, M | 1 |
| Afroz, S; Shen, H; Smith, SS | 1 |
| Angulo, MC; Audinat, E; Vélez-Fort, M | 1 |
| Agüeros, C; Arias, M; Benito, A; Cosme, LS; Gimenez, T; Gómez-Alamillo, C; Merino, J; Merino, R; Ramos-Barrón, MA; Santiuste, I | 1 |
| Calarge, CA; Miller, del D | 1 |
| Chen, G; Gong, M; Wang, HM; Xu, LH; Yan, M; Zhang, XM | 1 |
| Chen, C; Peng, M; Wang, CY; Wang, FF; Wang, YL | 1 |
| Fukuoka, N; Kimura, M; Morita, S; Tsukamoto, T; Uno, J | 1 |
| Aichhorn, W; Geretsegger, C; Kemmler, G; Marksteiner, J; Stelzig-Schoeler, R; Stuppaeck, C; Walch, T; Weiss, U; Zernig, G | 1 |
| Furst, DE; Ranganath, VK | 1 |
| Lauri, SE; Malkki, H; Sallert, M; Segerstråle, M; Taira, T | 1 |
| Diaz, FJ; Leon, Jd; Orrego, ML; Pan, RM; Susce, MT; Wedlund, PJ | 1 |
| Brust, P; Deuther-Conrad, W; Ebert, B; Friemel, A; Hutson, PH; Nieber, K | 1 |
| Mueller, AL; Schwartzkroin, PA; Taube, JS | 1 |
| Fitton, A; Grant, S | 1 |
| Bartlett, RR; Brendel, S; Schorlemmer, HU | 1 |
| Arneric, SP; Buccafusco, JJ; Decker, MW; Jackson, WJ; Marsh, KC; Prendergast, MA; Terry, AV | 1 |
| Bartlett, RR; Schorlemmer, HU | 1 |
| Andiné, P; Axelsson, R; Mårtensson, E; Nyberg, G; Olofsson, U; Sandberg, M; Widermark, N | 1 |
| Huettner, JE; Wilding, TJ | 1 |
| Kastango, KB; Kirshner, MA; Maxwell, RA; Mulsant, BH; Pollock, BG; Rosen, J; Sweet, RA | 1 |
| Ebbesson, SO; Erdö, SL; Hofmann, MH; Malz, CR; Meyer, DL | 1 |
| Gregus, Z; Klaassen, CD; Stein, AF | 1 |
| Kanai, S; Kitani, K; Masuda, Y; Nokubo, M; Ohta, M; Sato, Y | 1 |
3 review(s) available for isoxazoles and Aging
| Article | Year |
|---|---|
[Epilepsy in the elderly].
Topics: Age Factors; Aged; Aging; Anticonvulsants; Dose-Response Relationship, Drug; Epilepsy; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Piracetam; Quality of Life; Seizures; Triazines; Zonisamide | 2013 |
Disease-modifying antirheumatic drug use in the elderly rheumatoid arthritis patient.
Topics: Aged; Aging; Antimalarials; Antirheumatic Agents; Arthritis, Rheumatoid; Glomerular Filtration Rate; Humans; Isoxazoles; Leflunomide; Methotrexate; Sulfasalazine | 2007 |
Risperidone. A review of its pharmacology and therapeutic potential in the treatment of schizophrenia.
Topics: Absorption; Adult; Aged; Aging; Animals; Antipsychotic Agents; Central Nervous System; Cross-Over Studies; Disease Models, Animal; Drug Interactions; Hemodynamics; Humans; Isoxazoles; Neurosecretory Systems; Piperidines; Risperidone; Schizophrenia; Synaptic Transmission; Tissue Distribution | 1994 |
2 trial(s) available for isoxazoles and Aging
| Article | Year |
|---|---|
A study of genetic (CYP2D6 and ABCB1) and environmental (drug inhibitors and inducers) variables that may influence plasma risperidone levels.
Topics: Adult; Aging; Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Female; Humans; Isoxazoles; Linear Models; Male; Middle Aged; Organic Anion Transporters; Paliperidone Palmitate; Pyrimidines; Risperidone; Sex Factors | 2007 |
Risperidone. A review of its pharmacology and therapeutic potential in the treatment of schizophrenia.
Topics: Absorption; Adult; Aged; Aging; Animals; Antipsychotic Agents; Central Nervous System; Cross-Over Studies; Disease Models, Animal; Drug Interactions; Hemodynamics; Humans; Isoxazoles; Neurosecretory Systems; Piperidines; Risperidone; Schizophrenia; Synaptic Transmission; Tissue Distribution | 1994 |
23 other study(ies) available for isoxazoles and Aging
| Article | Year |
|---|---|
ISX-9 potentiates CaMKIIδ-mediated BMAL1 activation to enhance circadian amplitude.
Topics: Aging; Animals; ARNTL Transcription Factors; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Circadian Rhythm; Homeostasis; Isoxazoles; Mice; Sleep; Thiophenes | 2022 |
Parecoxib alleviates the motor behavioral decline of aged rats by ameliorating mitochondrial dysfunction in the substantia nigra via COX-2/PGE2 pathway inhibition.
Topics: Aging; Animals; Calcium-Binding Proteins; Cyclooxygenase 2; Cytokines; Dinoprostone; Dopamine Plasma Membrane Transport Proteins; Isoxazoles; Male; Microfilament Proteins; Microglia; Mitochondria; Mitochondrial Proteins; Motor Activity; Organelle Biogenesis; Protein Kinases; Rats; Rats, Sprague-Dawley; Substantia Nigra; Superoxide Dismutase; Tyrosine 3-Monooxygenase; Ubiquitin-Protein Ligases | 2021 |
Microwave-assisted synthesis of 3,5-disubstituted isoxazoles and evaluation of their anti-ageing activity.
Topics: Aging; Alkynes; Animals; Caenorhabditis elegans; Cell Line; Chemistry Techniques, Synthetic; Humans; Isoxazoles; Longevity; Microwaves; Oxidative Stress; Oxides; Stereoisomerism; Substrate Specificity | 2014 |
α4βδ GABA
Topics: Aging; Animals; CA1 Region, Hippocampal; Dendritic Spines; Female; GABA-A Receptor Agonists; Isoxazoles; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Neurons; Pregnanolone; Receptors, GABA-A; Spatial Learning | 2017 |
Functional alpha 7-containing nicotinic receptors of NG2-expressing cells in the hippocampus.
Topics: Age Factors; Aging; Allosteric Regulation; alpha7 Nicotinic Acetylcholine Receptor; Animals; Animals, Newborn; Antigens; Cell Differentiation; Cell Proliferation; Dose-Response Relationship, Drug; Hippocampus; Ion Channel Gating; Isoxazoles; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Oligodendroglia; Organ Culture Techniques; Patch-Clamp Techniques; Phenylurea Compounds; Proteoglycans; Receptors, Nicotinic; Stem Cells | 2009 |
Leflunomide derivative FK778 inhibits production of antibodies in an experimental model of alloreactive T-B cell interaction.
Topics: Age Factors; Aging; Alkynes; Animals; Antibody Formation; Autoantibodies; B-Lymphocytes; Dose-Response Relationship, Drug; Genes, bcl-2; Humans; Immunosuppressive Agents; Isoxazoles; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Nitriles; T-Lymphocytes; Transplantation Tolerance | 2009 |
Predictors of risperidone and 9-hydroxyrisperidone serum concentration in children and adolescents.
Topics: Adolescent; Aging; Antipsychotic Agents; Body Mass Index; Child; Child Development Disorders, Pervasive; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Drug Therapy, Combination; Female; Humans; Isoxazoles; Male; Mental Disorders; Paliperidone Palmitate; Polypharmacy; Psychotic Disorders; Pyrimidines; Risperidone; Sex Factors; Sexual Development | 2011 |
Parecoxib mitigates spatial memory impairment induced by sevoflurane anesthesia in aged rats.
Topics: Aging; Anesthetics, Intravenous; Animals; Blotting, Western; Cognition Disorders; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Hippocampus; Isoxazoles; Male; Maze Learning; Memory; Memory Disorders; Methyl Ethers; Microscopy, Electron, Transmission; Rats; Rats, Sprague-Dawley; Sevoflurane; Synapses | 2012 |
The cyclooxygenase-2 inhibitor parecoxib inhibits surgery-induced proinflammatory cytokine expression in the hippocampus in aged rats.
Topics: Aging; Animals; Cognition Disorders; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Encephalitis; Gene Expression; Hippocampus; Interleukin-1beta; Isoxazoles; Male; Postoperative Complications; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2012 |
Influence of coadministered antiepileptic drugs on serum zonisamide concentrations in epileptic patients: quantitative analysis based on suitable transforming factor.
Topics: Administration, Oral; Adolescent; Adult; Aging; Anticonvulsants; Biological Availability; Body Surface Area; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Isoxazoles; Male; Patient Selection; Phenytoin; Powders; Regression Analysis; Sex; Tablets; Zonisamide | 2003 |
Influence of age and gender on risperidone plasma concentrations.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Antipsychotic Agents; Biotransformation; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Female; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Pyrimidines; Risperidone; Sex Characteristics | 2005 |
Effects of the kainate receptor agonist ATPA on glutamatergic synaptic transmission and plasticity during early postnatal development.
Topics: Aging; Animals; Animals, Newborn; Electrophysiology; Excitatory Amino Acid Agonists; Glutamates; Hippocampus; In Vitro Techniques; Isoxazoles; Neuronal Plasticity; Propionates; Rats; Rats, Wistar; Receptors, Kainic Acid; Signal Transduction; Synapses; Synaptic Transmission | 2007 |
Postnatal development and kinetics of [3H]gaboxadol binding in rat brain: in vitro homogenate binding and quantitative autoradiography.
Topics: Aging; Animals; Animals, Newborn; Autoradiography; Binding, Competitive; Brain; Brain Chemistry; Flunitrazepam; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Isoxazoles; Kinetics; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Subcellular Fractions | 2007 |
Development of hyperpolarizing inhibitory postsynaptic potentials and hyperpolarizing response to gamma-aminobutyric acid in rabbit hippocampus studied in vitro.
Topics: Action Potentials; Aging; Animals; Animals, Newborn; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Isoxazoles; Membrane Potentials; Neurons; Rabbits; Synapses | 1984 |
Malononitrilamides prevent the development of murine systemic lupus erythematosus-like diseases in BDF1 hybrid mice and MRL/lpr autoimmune mice.
Topics: Aging; Alkynes; Animals; Antibody Formation; Crosses, Genetic; Disease Models, Animal; Female; Graft vs Host Disease; Immunoglobulin E; Immunoglobulin G; Immunosuppressive Agents; Isoxazoles; Lupus Erythematosus, Systemic; Mice; Mice, Inbred DBA; Mice, Mutant Strains; Nitriles | 1996 |
Improvement in accuracy of delayed recall in aged and non-aged, mature monkeys after intramuscular or transdermal administration of the CNS nicotinic receptor agonist ABT-418.
Topics: Administration, Cutaneous; Aging; Anti-Anxiety Agents; Female; Humans; Injections, Intramuscular; Isoxazoles; Male; Mental Recall; Pyrrolidines; Time Factors | 1997 |
Prevention of the development of murine systemic lupus erythematosus (SLE)-like diseases by the malononitrilamides MNA 279 and MNA 715.
Topics: Aging; Alkynes; Animals; Autoimmune Diseases; Female; Immunosuppressive Agents; Isoxazoles; Kinetics; Lupus Erythematosus, Systemic; Lymph Nodes; Mice; Mice, Inbred DBA; Nitriles; Spleen; Splenomegaly | 1997 |
Characterization of MK-801-induced behavior as a putative rat model of psychosis.
Topics: Aging; Animals; Brain; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Isoxazoles; Male; Motor Activity; Psychoses, Substance-Induced; Rats; Rats, Sprague-Dawley; Receptors, GABA; Sex Characteristics; Stereotyped Behavior; Stereotypic Movement Disorder | 1999 |
Functional diversity and developmental changes in rat neuronal kainate receptors.
Topics: Aging; Animals; Animals, Newborn; Cells, Cultured; Electric Conductivity; Embryo, Mammalian; Excitatory Amino Acid Agonists; Ganglia, Spinal; Hippocampus; Isoxazoles; Kainic Acid; Neurons; Propionates; Rats; Rats, Long-Evans; Receptors, Kainic Acid; Spinal Cord | 2001 |
Risperidone and 9-hydroxyrisperidone concentrations are not dependent on age or creatinine clearance among elderly subjects.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Antipsychotic Agents; Creatinine; Female; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Pyrimidines; Radioimmunoassay; Risperidone | 2002 |
Changes in ligand binding to GABAA receptor sites in pacific salmon (Oncorhynchus) brain during spawning migration and "aging".
Topics: Aging; Aminobutyrates; Analgesics; Animals; Baclofen; Bicuculline; Binding, Competitive; Brain; Female; gamma-Aminobutyric Acid; Isoxazoles; Kinetics; Ligands; Male; Muscimol; Receptors, GABA-A; Salmon; Sexual Behavior, Animal | 1992 |
Age-dependent biliary excretion of glutathione-related thiols in rats: role of gamma-glutamyltransferase.
Topics: Aging; Animals; Bile; Disulfides; gamma-Glutamyltransferase; Glutathione; Hydrolysis; Isoxazoles; Liver; Male; Oxidation-Reduction; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Sulfur | 1987 |
Increasing anticonvulsant effect of AD-810 (zonisamide) in aging BDF1 mice.
Topics: Aging; Animals; Anticonvulsants; Brain; Dose-Response Relationship, Drug; Isoxazoles; Mice; Oxazoles; Zonisamide | 1987 |