Compounds > isoxazoles
Page last updated: 2024-08-21

isoxazoles and African Sleeping Sickness

isoxazoles has been researched along with African Sleeping Sickness in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Caton, E; Meyer, KJ; Shapiro, TA1
Bakunov, SA; Bakunova, SM; Brun, R; Patrick, DA; Tidwell, RR; Wenzler, T1
Barrett, MP; Conti, P; Cosconati, S; De Micheli, C; Iannuzzi, MC; Lo Presti, L; Major, LL; Marinelli, L; Novellino, E; Pinto, A; Smith, TK; Tamborini, L; Wong, PE1
Jennings, FW; Miller, BM; Murray, PK; Urquhart, GM1
Brun, R; Chabes, A; Hofer, A; Steverding, D; Thelander, L1

Other Studies

5 other study(ies) available for isoxazoles and African Sleeping Sickness

ArticleYear
Model System Identifies Kinetic Driver of Hsp90 Inhibitor Activity against African Trypanosomes and Plasmodium falciparum.
    Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:8

    Topics: Animals; Antineoplastic Agents; Antiprotozoal Agents; Area Under Curve; Benzodioxoles; Benzoquinones; Biological Assay; Disease Models, Animal; Drug Repositioning; Female; Gene Expression; HSP90 Heat-Shock Proteins; Imidazoles; Isoxazoles; Lactams, Macrocyclic; Malaria, Falciparum; Mice; Models, Biological; Plasmodium falciparum; Protozoan Proteins; Resorcinols; Trypanosoma brucei brucei; Trypanosomiasis, African

2018
Antiprotozoal activity of dicationic 3,5-diphenylisoxazoles, their prodrugs and aza-analogues.
    Bioorganic & medicinal chemistry, 2014, Jan-01, Volume: 22, Issue:1

    Topics: Animals; Antiprotozoal Agents; Isoxazoles; Mice; Molecular Structure; Plasmodium falciparum; Prodrugs; Structure-Activity Relationship; Trypanosomiasis, African

2014
Synthesis and biological evaluation of CTP synthetase inhibitors as potential agents for the treatment of African trypanosomiasis.
    ChemMedChem, 2012, Volume: 7, Issue:9

    Topics: Carbon-Nitrogen Ligases; Enzyme Inhibitors; HeLa Cells; Humans; Isoxazoles; Molecular Docking Simulation; Pyrazoles; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2012
'Berenil' and nitroimidazole combinations in the treatment of Trypanosoma brucei infection with central nervous system involvement.
    International journal for parasitology, 1980, Volume: 10, Issue:1

    Topics: Amidines; Animals; Benzamidines; Central Nervous System Diseases; Diminazene; Ethidium; Female; Isoxazoles; Mice; Nitroimidazoles; Phenanthridines; Ronidazole; Time Factors; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1980
Trypanosoma brucei CTP synthetase: a target for the treatment of African sleeping sickness.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, May-22, Volume: 98, Issue:11

    Topics: Adenosine Triphosphate; Animals; Carbon-Nitrogen Ligases; Cells, Cultured; Cytidine; Cytidine Triphosphate; Diazooxonorleucine; Enzyme Inhibitors; Fibroblasts; Guanine; Guanosine Triphosphate; Humans; Hypoxanthines; Intracellular Fluid; Isoxazoles; Mice; Mice, Inbred BALB C; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African; Uridine Triphosphate

2001