isoxazoles has been researched along with Acute Liver Injury, Drug-Induced in 43 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (2.33) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 15 (34.88) | 29.6817 |
2010's | 27 (62.79) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Bae, GH; Bae, YS; Kim, HS; Lee, HY; Lee, M; Lee, SK | 1 |
Deng, WH; Guo, ZD; Hong, YP; Shi, Q; Wang, P; Wang, WX; Zhao, L; Zuo, T | 1 |
Couch, L; Guo, L; Qing, T; Ren, Z; Shi, L; Tolleson, WH; Xuan, J | 1 |
Catalá-López, F; de la Fuente Honrubia, C; Macías Saint-Gerons, D; Montero Corominas, D | 1 |
Andersson, LC; Bergare, J; Billger, M; Eakins, JA; Elebring, M; Elmore, CS; Foster, AJ; Kenna, JG; Stahl, SH; Thompson, RA | 1 |
Ali, EA; Bilasy, SE; Essawy, SS; Mandour, MF; Zaitone, SA | 1 |
Chen, CJ; Cheng, TT; Lin, JC; Lin, KM | 1 |
Chen, Z; Li, XM; Li, XP; Li, ZG; Su, Y; Xiang, N; Yang, M; Zhang, MJ; Zhao, DB; Zhu, P; Zuo, XX | 1 |
Fu, X; Huang, M; Huang, Z; Jin, J; Qiu, Y; Sun, X; Wang, W; Zhao, Z | 1 |
Alsleben, N; Donald, PR; Garcia-Prats, AJ; Hesseling, AC; Schaaf, HS; Willemse, M | 1 |
Cao, L; Cheng, X; Hao, H; Wang, G; Wang, H; Wu, M; Wu, Y; Xie, W; Xie, Y | 1 |
Cao, YY; Chen, C; Lin, YF; Luan, Y; Ma, LL; Ni, X; Pan, GY; Wang, J; Wang, L; Wu, ZT; Zhang, XF | 1 |
Goda, K; Kobayashi, A; Kuno, H; Shoda, T; Sugai, S; Takahashi, T | 1 |
Chan, EC; New, LS; Tan, SC | 1 |
Beukelman, T; Cassell, S; Curtis, JR; Greenberg, JD; Kavanaugh, A; Kremer, JM; Onofrei, A; Reed, G; Strand, V | 1 |
Aleksunes, LM; Cui, YJ; Goedken, MJ; Klaassen, CD; Tanaka, Y | 1 |
Golpon, H; Hoeper, MM; Olsson, KM; Schneider, A | 1 |
Hoeper, MM | 1 |
Gaine, SP; Kelleher, B; Lavelle, A; Lawler, G; Mulligan, N; Murphy, DM; Sugrue, R | 1 |
Andrade, RJ; Cotta, J; Lucena, MA; Robles, M; Toscano, E | 1 |
Hinton, DE; Howarth, DL; Kullman, SW; Law, JM; Law, SH; Mondon, JA | 1 |
Corris, PA; Langleben, D | 1 |
Gründer, G; Orfanos, S; Paulzen, M | 1 |
Galiè, N; Gibbs, JS; Hoeper, MM; Simonneau, G | 1 |
Fisher, AJ; Johnson, MK; Kirkham, N; Lee, WT; Lordan, JL; Peacock, AJ | 1 |
Galiè, N; Gibbs, R; Hoeper, MM; Simon, J; Simonneau, G | 1 |
Chen, B; Huang, WH; Lee, AR; Media, J; Shaw, J; Valeriote, FA | 1 |
Muñana, KR; Olby, NJ; Schwartz, M | 1 |
Bhatia, J; Gupta, R; Gupta, SK | 1 |
Izuta, S; Maekawa, N; Nishina, K; Shiozawa, S; Ueki, M; Ueno, M | 1 |
Gučev, F; Hočevar, A; Marolt, VF; Perdan-Pirkmajer, K; Rotar, Ž; Tomšič, M; Žibert, J | 1 |
Dulaurent, S; Gaulier, JM; Lachâtre, G; Moesch, C; Zouaoui, K | 1 |
Grove, ML | 1 |
Jin, Y; Li, CY; Li, J; Xu, SY; Yao, HW; Zhang, YF | 1 |
Agúndez, JA; Díaz-Rubio, M; Fernández-Gutiérrez, B; Ladero, JM; Ortega, L; Sevilla-Mantilla, C | 1 |
Brouwers, JR; Houtman, NM; Jansen, TL; Spoelstra, P; van Roon, EN | 1 |
Bitton, A; Ernst, P; Hudson, M; Kezouh, A; Suissa, S | 1 |
Gupta, R; Gupta, SK | 1 |
Choi, K; Khosla, C; Kosek, JC; Omary, MB; Siegel, M; Strnad, P; Toivola, DM | 1 |
Saito, E; Suwa, A; Suzuki, Y; Wakabayashi, T | 1 |
Hartmann, U; Reuss-Borst, M; Schmitt, S | 1 |
Breedveld, FC | 1 |
Tiegs, G; Wendel, A | 1 |
2 review(s) available for isoxazoles and Acute Liver Injury, Drug-Induced
Article | Year |
---|---|
[Hepatotoxicity in patients treated with endothelin receptor antagonists: systematic review and meta-analysis of randomized clinical trials].
Topics: Antihypertensive Agents; Biomarkers; Bosentan; Chemical and Drug Induced Liver Injury; Endothelin Receptor Antagonists; Humans; Hypertension; Isoxazoles; Phenylpropionates; Pyridazines; Randomized Controlled Trials as Topic; Safety-Based Drug Withdrawals; Sulfonamides; Thiophenes; Transaminases | 2014 |
[Adverse effects of conventional DMARDs and biologic DMARDs].
Topics: Antibodies, Monoclonal; Antirheumatic Agents; Chemical and Drug Induced Liver Injury; Cysteine; Drug Eruptions; Drug Hypersensitivity; Hematologic Diseases; Humans; Immune System Diseases; Infliximab; Isoxazoles; Kidney Diseases; Leflunomide; Lung Diseases; Methotrexate | 2007 |
2 trial(s) available for isoxazoles and Acute Liver Injury, Drug-Induced
Article | Year |
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Total glucosides of paeony can reduce the hepatotoxicity caused by Methotrexate and Leflunomide combination treatment of active rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Female; Glucosides; Humans; Isoxazoles; Leflunomide; Male; Methotrexate; Middle Aged; Paeonia; Treatment Outcome; Young Adult | 2015 |
Risk of hepatotoxicity with add-on leflunomide in rheumatoid arthritis patients.
Topics: Adult; Aged; Alanine Transaminase; Antirheumatic Agents; Arthritis, Rheumatoid; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Female; Humans; Isoxazoles; Leflunomide; Male; Methotrexate; Middle Aged; Prospective Studies; Risk | 2011 |
39 other study(ies) available for isoxazoles and Acute Liver Injury, Drug-Induced
Article | Year |
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Lysophosphatidic acid protects against acetaminophen-induced acute liver injury.
Topics: Acetaminophen; Animals; Apoptosis; Chemical and Drug Induced Liver Injury; Gene Expression Regulation; Hepatocytes; Humans; Interleukin-1beta; Isoxazoles; Liver; Lysophospholipids; Mice; Oxidative Stress; Propionates; Receptors, Lysophosphatidic Acid; Tumor Necrosis Factor-alpha | 2017 |
Fetal liver injury ameliorated by migration inhibitory factor inhibition in a rat model of acute pancreatitis in pregnancy.
Topics: Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Female; Isoxazoles; Macrophage Migration-Inhibitory Factors; Pancreatitis; Pregnancy; Pregnancy Complications; Prenatal Injuries; Rats; Rats, Sprague-Dawley | 2018 |
Mitochondrial dysfunction induced by leflunomide and its active metabolite.
Topics: Adenosine Triphosphate; Anti-Inflammatory Agents, Non-Steroidal; Bongkrekic Acid; Chemical and Drug Induced Liver Injury; Endoplasmic Reticulum Stress; Galactose; Glucose; Hep G2 Cells; Humans; Isoxazoles; L-Lactate Dehydrogenase; Leflunomide; Membrane Potential, Mitochondrial; Mitochondria, Liver; Mitochondrial Diseases; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oxidative Phosphorylation | 2018 |
Multiple compound-related adverse properties contribute to liver injury caused by endothelin receptor antagonists.
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Bosentan; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Epithelial Cells; Hepatocytes; Humans; Isoxazoles; Mitochondria; Molecular Structure; Oxygen Consumption; Phenylpropionates; Pyridazines; Sulfonamides; Thiophenes | 2015 |
Myelosuppressive and hepatotoxic potential of leflunomide and methotrexate combination in a rat model of rheumatoid arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Blood Cell Count; Bone Marrow; Bone Marrow Diseases; Chemical and Drug Induced Liver Injury; Cytokines; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Hindlimb; Isoxazoles; Leflunomide; Liver Cirrhosis; Male; Methotrexate; Rats; Rats, Wistar; Spleen | 2015 |
Tumor necrosis factor-α antagonist therapy for concomitant rheumatoid arthritis and hepatitis C virus infection: a case series study.
Topics: Adalimumab; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Chemical and Drug Induced Liver Injury; Cohort Studies; Cyclosporine; Drug Therapy, Combination; Etanercept; Female; Hepatitis C, Chronic; Humans; Hydroxychloroquine; Immunosuppressive Agents; Isoxazoles; Leflunomide; Male; Methotrexate; Middle Aged; Retrospective Studies; Sulfasalazine; Treatment Outcome; Tumor Necrosis Factor-alpha | 2015 |
Activation of the farnesoid X receptor attenuates triptolide-induced liver toxicity.
Topics: Animals; Chemical and Drug Induced Liver Injury; Diterpenes; Epoxy Compounds; Gene Knockdown Techniques; Hep G2 Cells; Humans; Isoxazoles; Liver; Male; Mice, Inbred BALB C; Phenanthrenes; Receptors, Cytoplasmic and Nuclear; RNA, Small Interfering | 2015 |
Successful Treatment of a Child With Extensively Drug-Resistant Tuberculous Meningitis.
Topics: Anti-Inflammatory Agents; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Child, Preschool; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Female; Humans; Hypothyroidism; Isoxazoles; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Oxazolidinones; Prednisolone; Treatment Outcome; Tuberculosis, Meningeal | 2015 |
Farnesoid X receptor activation promotes cell proliferation via PDK4-controlled metabolic reprogramming.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Chemical and Drug Induced Liver Injury; Cluster Analysis; Disease Models, Animal; Energy Metabolism; Glycolysis; Hep G2 Cells; Humans; Isoxazoles; Liver Regeneration; Metabolome; Metabolomics; Mice; Mice, Knockout; Models, Biological; Protein Kinases; Receptors, Cytoplasmic and Nuclear | 2016 |
Inhibition of hepatic cytochrome P450 enzymes and sodium/bile acid cotransporter exacerbates leflunomide-induced hepatotoxicity.
Topics: Animals; Antirheumatic Agents; Cells, Cultured; Chemical and Drug Induced Liver Injury; Crotonates; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Female; HEK293 Cells; Humans; Hydroxybutyrates; Isoxazoles; Leflunomide; Liver; Male; Mice, Inbred C57BL; Nitriles; Organic Anion Transporters, Sodium-Dependent; Rats, Sprague-Dawley; Symporters; Toluidines | 2016 |
Usefulness of in vitro combination assays of mitochondrial dysfunction and apoptosis for the estimation of potential risk of idiosyncratic drug induced liver injury.
Topics: Acetaminophen; Apoptosis; Biological Assay; Biomarkers; Caspase 3; Caspase 7; Cells, Cultured; Chemical and Drug Induced Liver Injury; Chromans; Diclofenac; Dose-Response Relationship, Drug; Ethanol; Hepatocytes; Humans; Isoxazoles; Leflunomide; Liver; Mitochondria, Liver; Oxygen Consumption; Primary Cell Culture; Ranitidine; Risk Assessment; Thiazolidinediones; Time Factors; Toxicity Tests; Troglitazone | 2016 |
Prevention of acetaminophen (APAP)-induced hepatotoxicity by leflunomide via inhibition of APAP biotransformation to N-acetyl-p-benzoquinone imine.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antirheumatic Agents; Benzoquinones; Biotransformation; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Data Interpretation, Statistical; Glutathione; Humans; Imines; Isoxazoles; Leflunomide; Mass Spectrometry; Mice; Microsomes, Liver; Phenacetin; Recombinant Proteins | 2008 |
Elevated liver enzyme tests among patients with rheumatoid arthritis or psoriatic arthritis treated with methotrexate and/or leflunomide.
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Antirheumatic Agents; Arthritis, Psoriatic; Arthritis, Rheumatoid; Aspartate Aminotransferases; Biomarkers; Chemical and Drug Induced Liver Injury; Clinical Enzyme Tests; Cohort Studies; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Isoxazoles; Leflunomide; Male; Methotrexate; Middle Aged; Young Adult | 2010 |
Compensatory induction of liver efflux transporters in response to ANIT-induced liver injury is impaired in FXR-null mice.
Topics: 1-Naphthylisothiocyanate; Alanine Transaminase; Animals; Aspartate Aminotransferases; Bile Acids and Salts; Biomarkers; Branched DNA Signal Amplification Assay; Carrier Proteins; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Fluorescent Antibody Technique; Isoxazoles; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA | 2009 |
Severe hepatitis associated with sitaxentan and response to glucocorticoid therapy.
Topics: Chemical and Drug Induced Liver Injury; Eisenmenger Complex; Endothelin Receptor Antagonists; Female; Glucocorticoids; Humans; Isoxazoles; Liver Function Tests; Thiophenes; Young Adult | 2009 |
Liver toxicity: the Achilles' heel of endothelin receptor antagonist therapy?
Topics: Chemical and Drug Induced Liver Injury; Endothelin Receptor Antagonists; Humans; Isoxazoles; Thiophenes | 2009 |
Sitaxentan-induced hepatic failure in two patients with pulmonary arterial hypertension.
Topics: Aged; Chemical and Drug Induced Liver Injury; Endothelin Receptor Antagonists; Female; Humans; Hypertension, Pulmonary; Isoxazoles; Male; Middle Aged; Thiophenes | 2009 |
[Hepatotoxicity induced by new immunosuppressants].
Topics: Azathioprine; Chemical and Drug Induced Liver Injury; Cyclosporine; Humans; Immunosuppressive Agents; Isoxazoles; Leflunomide; Methotrexate; Tumor Necrosis Factor-alpha | 2010 |
Exposure to the synthetic FXR agonist GW4064 causes alterations in gene expression and sublethal hepatotoxicity in eleutheroembryo medaka (Oryzias latipes).
Topics: Animals; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Embryo, Nonmammalian; Female; Gene Expression Regulation, Developmental; Isoxazoles; Liver; Male; Oryzias; Protein Isoforms; Receptors, Cytoplasmic and Nuclear; Yolk Sac | 2010 |
The Achilles heel of endothelin receptor therapy for pulmonary arterial hypertension.
Topics: Bosentan; Chemical and Drug Induced Liver Injury; Endothelin Receptor Antagonists; Humans; Hypertension, Pulmonary; Isoxazoles; Liver; Phenotype; Receptors, Endothelin; Sulfonamides; Thiophenes | 2010 |
Remission of drug-induced hepatitis after switching from risperidone to paliperidone.
Topics: Adult; Antipsychotic Agents; Biotransformation; Chemical and Drug Induced Liver Injury; Clozapine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Isoxazoles; Liver Function Tests; Paliperidone Palmitate; Pyrimidines; Reference Values; Risperidone; Schizophrenia | 2010 |
Liver toxicity of sitaxentan in pulmonary arterial hypertension.
Topics: Chemical and Drug Induced Liver Injury; Contraindications; Endothelin Receptor Antagonists; Familial Primary Pulmonary Hypertension; Humans; Hypertension, Pulmonary; Isoxazoles; Liver Failure; Practice Guidelines as Topic; Thiophenes | 2011 |
Sitaxentan-related acute liver failure in a patient with pulmonary arterial hypertension.
Topics: Chemical and Drug Induced Liver Injury; Contraindications; Endothelin A Receptor Antagonists; Familial Primary Pulmonary Hypertension; Fatal Outcome; Female; Humans; Hypertension, Pulmonary; Isoxazoles; Jaundice; Liver Failure, Acute; Piperazines; Purines; Sildenafil Citrate; Sulfones; Thiophenes; Vasodilator Agents; Young Adult | 2011 |
Liver toxicity of sitaxentan in pulmonary arterial hypertension.
Topics: Antihypertensive Agents; Chemical and Drug Induced Liver Injury; Early Termination of Clinical Trials; Endothelin Receptor Antagonists; Familial Primary Pulmonary Hypertension; Humans; Hypertension, Pulmonary; Isoxazoles; Safety-Based Drug Withdrawals; Thiophenes | 2011 |
The small-molecule TNF-alpha modulator, UTL-5g, reduces side effects induced by cisplatin and enhances the therapeutic effect of cisplatin in vivo.
Topics: Animals; Antineoplastic Agents; Blood Urea Nitrogen; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Cisplatin; Colonic Neoplasms; Female; Hematologic Diseases; Humans; Isoxazoles; Kidney Diseases; Lethal Dose 50; Male; Mice; Mice, Inbred ICR; Mice, SCID; Platelet Count; Toxicity Tests, Acute; Tumor Necrosis Factor-alpha | 2011 |
Possible drug-induced hepatopathy in a dog receiving zonisamide monotherapy for treatment of cryptogenic epilepsy.
Topics: Animals; Anticonvulsants; Chemical and Drug Induced Liver Injury; Dog Diseases; Dogs; Epilepsy; Female; Isoxazoles; Zonisamide | 2011 |
T-5224, a selective inhibitor of c-Fos/activator protein-1, attenuates lipopolysaccharide-induced liver injury in mice.
Topics: Animals; Benzophenones; Chemical and Drug Induced Liver Injury; Cytokines; Disease Models, Animal; Enzymes; Gastrointestinal Agents; Hepatitis, Animal; Isoxazoles; Lipopolysaccharides; Liver; Mice; Survival Analysis | 2012 |
Tumour necrosis factor-alpha inhibitor-induced hepatic injury in patients with rheumatoid arthritis: two case reports and an analysis of the laboratory data from the Slovenian national biologicals registry.
Topics: Adalimumab; Adult; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Biological Products; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Humans; Isoxazoles; Leflunomide; Male; Methotrexate; Methylprednisolone; Registries; Slovenia; Sulfasalazine; Tumor Necrosis Factor-alpha | 2013 |
Determination of glyphosate and AMPA in blood and urine from humans: about 13 cases of acute intoxication.
Topics: Accidents; Acidosis; Adult; Aged; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Consciousness Disorders; Deglutition Disorders; Disseminated Intravascular Coagulation; Female; Forensic Toxicology; Glycine; Glyphosate; Heart Arrest; Hemodynamics; Herbicides; Humans; Hyperkalemia; Isoxazoles; Lactic Acid; Male; Mass Spectrometry; Middle Aged; Multiple Organ Failure; Nausea; Organophosphonates; Oropharynx; Pharyngeal Diseases; Pharyngitis; Renal Insufficiency; Respiratory Distress Syndrome; Shock; Suicide; Tetrazoles; Ulcer; Vomiting | 2013 |
US Food and Drug Administration gets it right.
Topics: Cardiovascular Diseases; Chemical and Drug Induced Liver Injury; Cyclooxygenase 2; Drug Approval; Humans; Isoenzymes; Isoxazoles; Leflunomide; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Records; United Kingdom; United States; United States Food and Drug Administration | 2002 |
[Effects of leflunomide on immunological liver injury].
Topics: Adjuvants, Immunologic; Animals; Cell Division; Chemical and Drug Induced Liver Injury; Interleukin-1; Isoxazoles; Leflunomide; Lipopolysaccharides; Lymphocytes; Male; Mice; Nitric Oxide; Tumor Necrosis Factor-alpha | 2001 |
Leflunomide-induced acute hepatitis.
Topics: Adjuvants, Immunologic; Aged; Anion Exchange Resins; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Cholestyramine Resin; Female; Humans; Isoxazoles; Leflunomide; Liver | 2004 |
Leflunomide for the treatment of rheumatoid arthritis in clinical practice: incidence and severity of hepatotoxicity.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Chemical and Drug Induced Liver Injury; Female; Humans; Isoxazoles; Jaundice; Leflunomide; Male; Middle Aged | 2004 |
Newer disease-modifying antirheumatic drugs and the risk of serious hepatic adverse events in patients with rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Case-Control Studies; Chemical and Drug Induced Liver Injury; Female; Follow-Up Studies; Humans; Isoxazoles; Leflunomide; Liver; Liver Diseases; Male; Middle Aged; Retrospective Studies; Risk Factors; Severity of Illness Index; Treatment Outcome; United States | 2004 |
Severe hepatotoxicity in a rheumatoid arthritis patient switched from leflunomide to methotrexate.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Female; Humans; Isoxazoles; Leflunomide; Methotrexate; Severity of Illness Index | 2005 |
Pharmacologic transglutaminase inhibition attenuates drug-primed liver hypertrophy but not Mallory body formation.
Topics: Animals; Cell Size; Chemical and Drug Induced Liver Injury; Dicarbethoxydihydrocollidine; Enzyme Inhibitors; GTP-Binding Proteins; Hepatomegaly; Humans; Inclusion Bodies; Isoxazoles; Keratins; Liver Diseases; Mice; Mice, Inbred C3H; Protein Glutamine gamma Glutamyltransferase 2; Proteins; Transglutaminases | 2006 |
[Elevated liver enzymes in rheumatoid arthritis : differential diagnostic considerations based on a case report].
Topics: Adalimumab; Adolescent; Alanine Transaminase; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Aspartate Aminotransferases; Azathioprine; Biopsy; Chemical and Drug Induced Liver Injury; Cortisone; Diagnosis, Differential; Drug Therapy, Combination; Female; Hepatitis, Autoimmune; Humans; Isoxazoles; Leflunomide; Liver; Liver Function Tests; Methotrexate; Prednisolone | 2008 |
Is there a place for leflunomide in the treatment of rheumatoid arthritis?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Drug Interactions; Humans; Isoxazoles; Leflunomide; Methotrexate; Randomized Controlled Trials as Topic | 2001 |
Leukotriene-mediated liver injury.
Topics: Animals; Chemical and Drug Induced Liver Injury; Endotoxins; Galactosamine; Glutathione; Isoxazoles; Leukotriene E4; Liver; Male; Mice; SRS-A | 1988 |