Page last updated: 2024-08-21

isoxazoles and Acute Disease

isoxazoles has been researched along with Acute Disease in 68 studies

Research

Studies (68)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.47)	18.7374
1990's	16 (23.53)	18.2507
2000's	37 (54.41)	29.6817
2010's	12 (17.65)	24.3611
2020's	2 (2.94)	2.80

Authors

Authors	Studies
Kan, HP; Tan, JH; Zhang, GW; Zhou, L	1
Crippa, A; Davis, JM; Leucht, S; Orsini, N; Patel, MX; Siafis, S	1
Ding, Y; Hu, W; Wang, B; Wang, W; Zhao, K	1
Chen, Y; Deng, J; Fu, J; Guo, G; Li, J; Li, X; Tong, A; Wang, Y; Yuan, J	1
Chang, RJ; Huang, HL; Liang, ZH; Qin, HP; Qin, MB; Tang, GD; Wang, XM	1
Ceskova, E; Hublova, V; Kasparek, T; Kucerova, HP; Mayerova, M; Prikryl, R; Ustohal, L	1
Bartosiewicz, M; Bartoszuk, I; Jakubowska, L; Kuś, J; Siemion-Szcześniak, I; Wesołowski, S	1
Weiler, DL	1
Caballero, J; Marino, J	1
Berwaerts, J; Eerdekens, M; Emsley, R; Hough, D; Kramer, M; Lane, R; Lim, P; Palumbo, J	1
Bucher, M; Höcherl, K; Schmidt, C	1
Herrndobler, F; Koppert, W; Maihöfner, C; Ringler, R	1
Cook, JM; Groenink, L; Hopkins, SC; Klanker, M; Korte, SM; Olivier, B; Van Linn, ML; Vinkers, CH	1
Derry, S; Lloyd, R; McQuay, HJ; Moore, RA	1
Abbate, A; Hoke, NN; Houser, JE; Ownby, ED; Salloum, FN; Seropian, IM; Van Tassell, BW; Varma, A	1
Alphs, L; Bossie, CA; Canuso, CM; Turkoz, I	1
Abramowicz, D; Faoro, V; Huez, S; Lamotte, M; Naeije, R; Neupane, S; Retailleau, K	1
Gopal, S; Herben, V; Kusumakar, V; Lim, P; Lindenmayer, JP; Lull, J; Palumbo, J; Pandina, GJ; Yuen, E	1
Berwaerts, J; Hough, D; Lim, P; Nuamah, I; Xu, H	1
Hough, D; Nuamah, I; Robb, A; Singh, J; Vijapurkar, U	1
Berwaerts, J; Lim, P; Melkote, R; Nuamah, I	1
Badescu, GM; Bidzan, L; Hoeben, D; Jukić, V; Lahaye, M; Maciulis, V; Schmauss, M; Schreiner, A; Siracusano, A; Tessier, C	1
Bible, R; Findlay, JW; Karim, A; Yang, DC; Yuan, JJ; Zhang, JY	1
Fürstenberger, G; Hirschner, W; Marks, F; Müller-Decker, K	1
Rowbotham, DJ	1
Berigan, TR	1
Bekersky, I; Bilolo, KK; Chen, H; Fitzsimmons, WE; Hebert, MJ; Jiang, W; Ouyang, J; Qi, S; Wang, X; Xu, D; Zhu, S	1
Burian, M; Geisslinger, G	1
Cawkwell, GD; Christensen, KS	1
Pfeiffer, C; Schmitt, J; Wozel, G	1
Chang, R; Charpentier, B; Grinyó, JM; Jurewicz, A; Klinger, M; Kreis, H; Mourad, G; Neuhaus, P; Paczek, L; Paul, LC; Rostaing, L; Short, C; Squifflet, JP; van Hooff, JP; Vanrenterghem, Y; Wlodarczyk, Z	1
Böger, RH; Deuse, T; Koch-Nolte, F; Reichenspurner, H; Schäfer, H; Schrepfer, S; Schwedhelm, E	1
Baldassano, CF; Chang, A; Ghaemi, SN; Lipari, M; Lyman, A	1
Gulla, J; Lovell, SJ; Rodriguez, E; Singer, AJ; Taira, T; Wackett, A	1
Hirohashi, K; Ikeda, K; Kubo, S; Minamiyama, Y; Okuda, T; Suehiro, S; Takemura, S; Tanaka, H; Yamamoto, S; Yamasaki, K	1
Haneda, K; Iwamoto, M; Kamata, Y; Kamimura, T; Masuyama, J; Minota, S; Nara, H; Okazaki, H	1
Looney, Y; O'Dwyer, R; O'Shea, A	1
Deuse, T; Reichenspurner, H; Schäfer, H; Schrepfer, S	1
Floege, J; Mühlfeld, AS	1
Joshi, GP	1
Epstein, J; Klasser, GD	1
Cawkwell, GD; Hooper, M; Moskowitz, RW; Olson, NZ; Sunshine, A	1
Baldassano, CF; Dunn, RT; Filkowski, MM; Ghaemi, SN; Isenstein, E; Pardo, TB; Zablotsky, B	1
Coelho, AM; da Cunha, JE; de Almeida, JL; Jukemura, J; Machado, MC; Patzina, RA	1
Ludwig, EA; Piotrovsky, V; Vermeulen, A	1
Ben-Ezra, J; Massey, GV; Riley, RS; Russell, EC; Williams, DC	1
Deuse, T; Fischbein, MP; Pelletier, MP; Reichenspurner, H; Robbins, RC; Schrepfer, S	1
Cutler, AJ; Hamilton, J; Kalali, AH; Weiden, PJ; Wolfgang, CD	1
Bobo, WV; Eerdekens, M; Hough, D; Kramer, M; Lane, R; Meltzer, HY; Nuamah, IF	1
Fensbo, C; Høyberg, OJ; Lingjaerde, O; Remvig, J; Salvesen, I; Sloth-Nielsen, M	1
Heinrich, K; Hruschka, H; Kinzler, E; Klieser, E; Lehmann, E	1
Huttunen, MO; Larmo, I; Nyholm, R; Piepponen, T; Raitasuo, V; Rantanen, H	1
Goodnick, PJ	1
Bartlett, RR; Langer, KH; Mrowka, C; Thoenes, GH	1
Crawford, M; Griffiths, M; Keast, D; Palmer, TN; Patrick, G	1
Chong, AS; Clardy, C; Foster, P; McChesney, L; Sankary, H; Williams, JW; Xiao, F	1
Blinder, L; Chong, AS; Foster, P; Sankary, H; Shen, J; Wei, L; Williams, J; Xiao, F	1
Kurrle, R; Ruuth, E; Schorlemmer, HU; Schwab, W	1
Bartlett, RR; Schorlemmer, HU	2
Kurrle, R; Schorlemmer, HU	2
Kurrle, R; Ruuth, E; Schorlemmer, HU	1
Blinder, L; Chong, AS; Ma, LL; Sankary, H; Shen, J; Williams, JW; Yin, D	1
Chang, WH; Chiu, WC; Chou, JC; Lane, HY; Su, MH; Wu, ST	1
Jain, KK	1
Kissling, W; Möller, HJ; Pelzer, E; Riehl, T; Wernicke, T	1
Sahai, A; Tannen, RL	1

Reviews

9 review(s) available for isoxazoles and Acute Disease

Article	Year
Dose-Response Meta-Analysis of Antipsychotic Drugs for Acute Schizophrenia. The American journal of psychiatry, 2020, 04-01, Volume: 177, Issue:4 Topics: Acute Disease; Administration, Oral; Antipsychotic Agents; Aripiprazole; Clozapine; Delayed-Action Preparations; Dose-Response Relationship, Drug; Haloperidol; Humans; Imidazoles; Indoles; Isoxazoles; Lurasidone Hydrochloride; Olanzapine; Paliperidone Palmitate; Piperazines; Piperidines; Quetiapine Fumarate; Quinolones; Risperidone; Schizophrenia; Schizophrenic Psychology; Thiazoles; Thiophenes	2020
Paliperidone extended-release for the treatment of schizophrenia. Pharmacotherapy, 2008, Volume: 28, Issue:10 Topics: Acute Disease; Antipsychotic Agents; Delayed-Action Preparations; Drug Interactions; Fees, Pharmaceutical; Humans; Isoxazoles; Paliperidone Palmitate; Pyrimidines; Schizophrenia	2008
Efficacy and safety of oral paliperidone extended-release tablets in the treatment of acute schizophrenia: pooled data from three 52-week open-label studies. International clinical psychopharmacology, 2008, Volume: 23, Issue:6 Topics: Acute Disease; Administration, Oral; Adult; Antipsychotic Agents; Clinical Trials as Topic; Delayed-Action Preparations; Female; Humans; Isoxazoles; Male; Middle Aged; Multicenter Studies as Topic; Paliperidone Palmitate; Psychiatric Status Rating Scales; Pyrimidines; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index; Tablets; Time Factors; Treatment Outcome	2008
Intravenous or intramuscular parecoxib for acute postoperative pain in adults. The Cochrane database of systematic reviews, 2009, Apr-15, Issue:2 Topics: Acute Disease; Adult; Cyclooxygenase 2 Inhibitors; Humans; Injections, Intramuscular; Injections, Intravenous; Isoxazoles; Pain, Postoperative; Randomized Controlled Trials as Topic	2009
COX-2-selective inhibitors: clinical relevance in surgical and acute pain. European journal of anaesthesiology. Supplement, 2002, Volume: 25 Topics: Acute Disease; Analgesics; Animals; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Isoenzymes; Isoxazoles; Membrane Proteins; Pain; Pain, Postoperative; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides	2002
[Clinical pharmacology of the selective COX-2 inhibitors]. Der Orthopade, 2003, Volume: 32, Issue:12 Topics: Acute Disease; Administration, Oral; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Celecoxib; Clinical Trials, Phase III as Topic; Cyclooxygenase Inhibitors; Diclofenac; Humans; Isoxazoles; Lactones; Naproxen; Osteoarthritis; Pain; Pain, Postoperative; Placebos; Pyrazoles; Sulfonamides; Sulfones	2003
Valdecoxib for the management of chronic and acute pain. Expert review of neurotherapeutics, 2005, Volume: 5, Issue:1 Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Drug Evaluation; Expert Testimony; Humans; Isoxazoles; Narcotics; Pain; Product Surveillance, Postmarketing; Sulfonamides	2005
Nonsteroidal anti-inflammatory drugs: confusion, controversy and dental implications. Journal (Canadian Dental Association), 2005, Volume: 71, Issue:8 Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Chronic Disease; Clinical Trials as Topic; Cyclooxygenase 2 Inhibitors; Humans; Isoxazoles; Lactones; Myocardial Infarction; Peptic Ulcer; Pyrazoles; Sulfonamides; Sulfones; Toothache	2005
Evaluation of intravenous parecoxib for the relief of acute post-surgical pain. Expert opinion on investigational drugs, 2000, Volume: 9, Issue:11 Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Isoenzymes; Isoxazoles; Membrane Proteins; Pain, Postoperative; Prodrugs; Prostaglandin-Endoperoxide Synthases; Sulfonamides	2000

Trials

21 trial(s) available for isoxazoles and Acute Disease

Article	Year
[Modulation of cortical pain processing by cyclooxygenase inhibition: a functional MRI study]. Schmerz (Berlin, Germany), 2009, Volume: 23, Issue:2 Topics: Acute Disease; Adult; Analgesics; Aspirin; Brain Mapping; Cerebral Cortex; Cyclooxygenase Inhibitors; Dominance, Cerebral; Double-Blind Method; Female; Frontal Lobe; Gyrus Cinguli; Humans; Hyperalgesia; Image Processing, Computer-Assisted; Isoxazoles; Magnetic Resonance Imaging; Male; Motor Cortex; Pain; Pain Measurement; Pain Threshold; Parietal Lobe; Psychophysics; Somatosensory Cortex	2009
Paliperidone extended-release for schizophrenia: effects on symptoms and functioning in acutely ill patients with negative symptoms. Schizophrenia research, 2009, Volume: 113, Issue:1 Topics: Acute Disease; Adult; Analysis of Variance; Antipsychotic Agents; Dose-Response Relationship, Drug; Double-Blind Method; Drug Delivery Systems; Female; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Psychiatric Status Rating Scales; Pyrimidines; Schizophrenia; Schizophrenic Psychology; Treatment Outcome	2009
Pulmonary artery pressure limits exercise capacity at high altitude. The European respiratory journal, 2010, Volume: 36, Issue:5 Topics: Acute Disease; Adult; Altitude; Blood Pressure; Chronic Disease; Endothelin A Receptor Antagonists; Exercise; Female; Humans; Hypertension, Pulmonary; Hypoxia; Isoxazoles; Kidney; Male; Middle Aged; Oxygen Consumption; Pulmonary Artery; Pulmonary Gas Exchange; Thiophenes; Vascular Resistance; Young Adult	2010
A randomized, placebo-controlled study to assess the efficacy and safety of 3 doses of paliperidone palmitate in adults with acutely exacerbated schizophrenia. Journal of clinical psychopharmacology, 2010, Volume: 30, Issue:3 Topics: Acute Disease; Adult; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Isoxazoles; Male; Pain; Paliperidone Palmitate; Palmitates; Schizophrenia; Treatment Outcome; Young Adult	2010
Evaluation of the efficacy and safety of paliperidone extended-release in the treatment of acute mania: a randomized, double-blind, dose-response study. Journal of affective disorders, 2012, Volume: 136, Issue:1-2 Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Antipsychotic Agents; Bipolar Disorder; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Pyrimidines; Treatment Outcome; Young Adult	2012
A randomized, double-blind study of paliperidone extended-release in treatment of acute schizophrenia in adolescents. Biological psychiatry, 2011, Dec-15, Volume: 70, Issue:12 Topics: Acute Disease; Adolescent; Analysis of Variance; Antipsychotic Agents; Child; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Isoxazoles; Male; Paliperidone Palmitate; Psychology, Adolescent; Pyrimidines; Schizophrenia; Schizophrenic Psychology; Treatment Outcome	2011
A randomized, placebo- and active-controlled study of paliperidone extended-release as maintenance treatment in patients with bipolar I disorder after an acute manic or mixed episode. Journal of affective disorders, 2012, Volume: 138, Issue:3 Topics: Acute Disease; Adolescent; Adult; Aged; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Isoxazoles; Male; Middle Aged; Olanzapine; Paliperidone Palmitate; Pyrimidines; Secondary Prevention; Young Adult	2012
Flexible dosing with paliperidone ER in the treatment of patients with acutely exacerbated schizophrenia: results from a single-arm, open-label study. Current medical research and opinion, 2012, Volume: 28, Issue:8 Topics: Acute Disease; Adolescent; Adult; Aged; Antipsychotic Agents; Delayed-Action Preparations; Disease Progression; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Precision Medicine; Pyrimidines; Randomized Controlled Trials as Topic; Schizophrenia; Young Adult	2012
Disposition of a specific cyclooxygenase-2 inhibitor, valdecoxib, in human. Drug metabolism and disposition: the biological fate of chemicals, 2002, Volume: 30, Issue:9 Topics: Acute Disease; Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Antipruritics; Chromatography, High Pressure Liquid; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Feces; Glucuronidase; Humans; Isoenzymes; Isoxazoles; Male; Mass Spectrometry; Membrane Proteins; Pain; Prostaglandin-Endoperoxide Synthases; Sulfonamides	2002
Valdecoxib versus rofecoxib in acute postsurgical pain: results of a randomized controlled trial. Journal of pain and symptom management, 2004, Volume: 27, Issue:5 Topics: Acute Disease; Adolescent; Adult; Analgesics, Non-Narcotic; Cyclooxygenase Inhibitors; Double-Blind Method; Facial Pain; Female; Humans; Isoxazoles; Lactones; Male; Molar, Third; Pain, Postoperative; Sulfonamides; Sulfones; Tooth Extraction; Treatment Outcome; United States	2004
The effects of FK778 in combination with tacrolimus and steroids: a phase II multicenter study in renal transplant patients. Transplantation, 2004, Jul-15, Volume: 78, Issue:1 Topics: Acute Disease; Adolescent; Adult; Aged; Alkynes; Drug Therapy, Combination; Female; Glucocorticoids; Graft Rejection; Humans; Immunosuppressive Agents; Isoxazoles; Kidney Transplantation; Male; Middle Aged; Nitriles; Patient Compliance; Prednisolone; Tacrolimus; Treatment Outcome	2004
Comparison of valdecoxib and an oxycodone-acetaminophen combination for acute musculoskeletal pain in the emergency department: a randomized controlled trial. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2004, Volume: 11, Issue:12 Topics: Acetaminophen; Acute Disease; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Combinations; Emergency Medicine; Female; Humans; Isoxazoles; Male; Musculoskeletal Diseases; Oxycodone; Pain; Pain Measurement; Prospective Studies; Sulfonamides; Treatment Outcome	2004
An analgesic model for assessment of acute pain response in osteoarthritis of the knee. Osteoarthritis and cartilage, 2006, Volume: 14, Issue:11 Topics: Acute Disease; Aged; Aged, 80 and over; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Humans; Isoxazoles; Lactones; Male; Middle Aged; Models, Biological; Osteoarthritis, Knee; Pain Measurement; Severity of Illness Index; Sulfonamides; Sulfones; Time Factors; Treatment Outcome; Walking	2006
An open prospective study of zonisamide in acute bipolar depression. Journal of clinical psychopharmacology, 2006, Volume: 26, Issue:4 Topics: Acute Disease; Adult; Anticonvulsants; Bipolar Disorder; Depressive Disorder; Female; Humans; Isoxazoles; Male; Middle Aged; Nausea; Outpatients; Prospective Studies; Psychiatric Status Rating Scales; Time Factors; Treatment Outcome; Vomiting; Zonisamide	2006
Population pharmacokinetics of risperidone and 9-hydroxyrisperidone in patients with acute episodes associated with bipolar I disorder. Journal of pharmacokinetics and pharmacodynamics, 2007, Volume: 34, Issue:2 Topics: Acute Disease; Administration, Oral; Adult; Aged; Antipsychotic Agents; Bipolar Disorder; Computer Simulation; Cytochrome P-450 CYP2D6; Databases as Topic; Drug Administration Schedule; Female; Humans; Isoxazoles; Linear Models; Male; Middle Aged; Models, Biological; Paliperidone Palmitate; Phenotype; Population Surveillance; Pyrimidines; Reproducibility of Results; Risperidone; Tablets	2007
Four-week, double-blind, placebo- and ziprasidone-controlled trial of iloperidone in patients with acute exacerbations of schizophrenia. Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:2 Suppl 1 Topics: Acute Disease; Adolescent; Adult; Aged; Antipsychotic Agents; Double-Blind Method; Drug Administration Schedule; Female; Humans; Isoxazoles; Male; Middle Aged; Piperazines; Piperidines; Prospective Studies; Schizophrenia; Thiazoles; Treatment Outcome	2008
Efficacy and tolerability of oral paliperidone extended-release tablets in the treatment of acute schizophrenia: pooled data from three 6-week, placebo-controlled studies. The Journal of clinical psychiatry, 2008, Volume: 69, Issue:5 Topics: Acute Disease; Administration, Oral; Adult; Antipsychotic Agents; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Isoxazoles; Male; Paliperidone Palmitate; Pyrimidines; Retention, Psychology; Schizophrenia; Severity of Illness Index; Treatment Outcome	2008
Risperidone versus perphenazine in the treatment of chronic schizophrenic patients with acute exacerbations. Acta psychiatrica Scandinavica, 1993, Volume: 88, Issue:6 Topics: Acute Disease; Adult; Aged; Antipsychotic Agents; Denmark; Double-Blind Method; Female; Humans; Isoxazoles; Male; Middle Aged; Norway; Parkinson Disease, Secondary; Perphenazine; Piperidines; Prevalence; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index	1993
Risperidone versus clozapine in the treatment of schizophrenic patients with acute symptoms: a double blind, randomized trial. Progress in neuro-psychopharmacology & biological psychiatry, 1994, Volume: 18, Issue:1 Topics: Acute Disease; Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Clozapine; Double-Blind Method; Electrocardiography; Electroencephalography; Female; Humans; Infant, Newborn; Isoxazoles; Male; Middle Aged; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia, Paranoid	1994
Risperidone versus zuclopenthixol in the treatment of acute schizophrenic episodes: a double-blind parallel-group trial. Acta psychiatrica Scandinavica, 1995, Volume: 91, Issue:4 Topics: Acute Disease; Adolescent; Adult; Aged; Antipsychotic Agents; Clopenthixol; Double-Blind Method; Female; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology	1995
Risperidone in acutely exacerbated schizophrenia: dosing strategies and plasma levels. The Journal of clinical psychiatry, 2000, Volume: 61, Issue:3 Topics: Acute Disease; Adult; Antipsychotic Agents; Asian People; Drug Administration Schedule; Female; Hospitalization; Humans; Isoxazoles; Male; Paliperidone Palmitate; Patient Readmission; Pharmacogenetics; Prospective Studies; Psychiatric Status Rating Scales; Pyrimidines; Risperidone; Schizophrenia; Schizophrenic Psychology; Taiwan; Treatment Outcome	2000

Other Studies

38 other study(ies) available for isoxazoles and Acute Disease

Article	Year
Parecoxib Improves the Outcomes of Acute Mild and Moderate Pancreatitis: A 3-Year Matched Cohort Study Based on a Prospective Database. Pancreas, 2019, Volume: 48, Issue:9 Topics: Acute Disease; Adult; Bacterial Infections; Cohort Studies; Cyclooxygenase 2 Inhibitors; Databases, Factual; Disease Progression; Female; Fever; Humans; Isoxazoles; Male; Middle Aged; Outcome Assessment, Health Care; Pancreatitis; Protective Agents; Severity of Illness Index	2019
Protective Mechanism of MIF Inhibitor ISO-1 on Intrahepatic Bile Duct Cells in Rats with Severe Acute Pancreatitis. Digestive diseases and sciences, 2021, Volume: 66, Issue:10 Topics: Acute Disease; Animals; Bile Ducts, Intrahepatic; Cytokines; Gene Expression Regulation; Intramolecular Oxidoreductases; Isoxazoles; Macrophage Migration-Inhibitory Factors; Male; Pancreatitis; Random Allocation; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Specific Pathogen-Free Organisms	2021
Zonisamide-loaded triblock copolymer nanomicelles as a novel drug delivery system for the treatment of acute spinal cord injury. International journal of nanomedicine, 2017, Volume: 12 Topics: Acute Disease; Animals; Antioxidants; Axons; Blood-Brain Barrier; Cell Death; Chromatography, Gel; Dioxanes; Drug Carriers; Drug Delivery Systems; Drug Liberation; Isoxazoles; Magnetic Resonance Imaging; Mice; Micelles; Nanoparticles; Polyesters; Polyethylene Glycols; Polymers; Proton Magnetic Resonance Spectroscopy; Rats, Sprague-Dawley; Spectroscopy, Fourier Transform Infrared; Spinal Cord Injuries; X-Ray Diffraction; Zonisamide	2017
Role of Wnt/β-catenin pathway agonist SKL2001 in Caerulein-induced acute pancreatitis. Canadian journal of physiology and pharmacology, 2019, Volume: 97, Issue:1 Topics: Acute Disease; Animals; beta Catenin; Ceruletide; Female; Imidazoles; Isoxazoles; Male; Pancreatitis; Rats; Rats, Sprague-Dawley; Wnt Signaling Pathway	2019
Severe acute dystonia/akathisia after paliperidone palmitate application--a case study. The international journal of neuropsychopharmacology, 2014, Volume: 17, Issue:2 Topics: Acute Disease; Akathisia, Drug-Induced; Antipsychotic Agents; Dystonia; Humans; Isoxazoles; Male; Paliperidone Palmitate; Palmitates; Severity of Illness Index; Young Adult	2014
[Acute interstitial pneumonia in patient with rheumatoid arthritis treated with leflunomide]. Pneumonologia i alergologia polska, 2014, Volume: 82, Issue:6 Topics: Acute Disease; Antirheumatic Agents; Arthritis, Rheumatoid; Glucocorticoids; Humans; Idiopathic Interstitial Pneumonias; Isoxazoles; Leflunomide; Male; Middle Aged	2014
Zonisamide-induced angle closure and myopic shift. Optometry and vision science : official publication of the American Academy of Optometry, 2015, Volume: 92, Issue:2 Topics: Acute Disease; Adult; Anticonvulsants; Female; Glaucoma, Angle-Closure; Gonioscopy; Humans; Intraocular Pressure; Isoxazoles; Migraine Disorders; Myopia; Visual Acuity; Zonisamide	2015
COX-2 inhibition attenuates endotoxin-induced downregulation of organic anion transporters in the rat renal cortex. Kidney international, 2009, Volume: 75, Issue:4 Topics: Acute Disease; Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Down-Regulation; Isoxazoles; Kidney Cortex; Kidney Diseases; Lipopolysaccharides; Male; Organic Anion Transport Protein 1; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Rats; Rats, Sprague-Dawley	2009
Dissociating anxiolytic and sedative effects of GABAAergic drugs using temperature and locomotor responses to acute stress. Psychopharmacology, 2009, Volume: 204, Issue:2 Topics: Acute Disease; Anesthetics; Animals; Anti-Anxiety Agents; Body Temperature; Carbolines; Central Nervous System Depressants; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; GABA Agents; GABA Agonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Hypnotics and Sedatives; Isoxazoles; Male; Motor Activity; Pyridines; Rats; Rats, Wistar; Receptors, GABA-A; Stress, Psychological; Telemetry; Zolpidem	2009
Parecoxib inhibits apoptosis in acute myocardial infarction due to permanent coronary ligation but not due to ischemia-reperfusion. Journal of cardiovascular pharmacology, 2009, Volume: 53, Issue:6 Topics: Acute Disease; Animals; Apoptosis; Coronary Stenosis; Coronary Vessels; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Echocardiography; Injections, Intraperitoneal; Isoxazoles; Ligation; Male; Mice; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Ventricular Remodeling	2009
The effects of cyclooxygenase isozyme inhibition on incisional wound healing in mouse skin. The Journal of investigative dermatology, 2002, Volume: 119, Issue:5 Topics: Acute Disease; Animals; Collagen; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Female; Isoenzymes; Isoxazoles; Mice; Mice, Inbred Strains; Neovascularization, Physiologic; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Skin; Sulfonamides; Tensile Strength; Wound Healing	2002
Zonisamide treatment of bipolar disorder: a case report. Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2002, Volume: 47, Issue:9 Topics: Acute Disease; Anticonvulsants; Bipolar Disorder; Humans; Isoxazoles; Male; Middle Aged; Zonisamide	2002
Synergistic effects of malononitrilamides (FK778, FK779) with tacrolimus (FK506) in prevention of acute heart and kidney allograft rejection and reversal of ongoing heart allograft rejection in the rat. Transplantation, 2003, Jun-15, Volume: 75, Issue:11 Topics: Acute Disease; Alkynes; Animals; Drug Synergism; Graft Rejection; Heart Transplantation; Immunosuppressive Agents; Isoxazoles; Kidney; Kidney Transplantation; Male; Myocardium; Nitriles; Rats; Rats, Inbred ACI; Rats, Inbred BN; Rats, Inbred Lew; Tacrolimus; Transplantation, Homologous	2003
Leflunomide as a novel treatment option in severe atopic dermatitis. The British journal of dermatology, 2004, Volume: 150, Issue:6 Topics: Acute Disease; Adult; Dermatitis, Atopic; Drug Administration Schedule; Humans; Immunosuppressive Agents; Isoxazoles; Leflunomide; Male; Time Factors; Treatment Outcome	2004
FK778 attenuates lymphocyte-endothelium interaction after cardiac transplantation: in vivo and in vitro studies. Transplantation, 2004, Jul-15, Volume: 78, Issue:1 Topics: Acute Disease; Alkynes; Animals; Antineoplastic Agents; Cell Adhesion; Endothelial Cells; Graft Rejection; Heart Transplantation; In Vitro Techniques; Intercellular Adhesion Molecule-1; Iodine Radioisotopes; Isoxazoles; Lymphocytes; Nitriles; Rats; Rats, Inbred BN; Rats, Inbred Lew; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1	2004
Acute treatment of bipolar depression with adjunctive zonisamide: a retrospective chart review. Bipolar disorders, 2004, Volume: 6, Issue:5 Topics: Acute Disease; Adult; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Diagnostic and Statistical Manual of Mental Disorders; Drug Therapy, Combination; Female; Humans; Isoxazoles; Male; Retrospective Studies; Severity of Illness Index; Zonisamide	2004
FK778 and FK506 combination therapy to control acute rejection after rat liver allotransplantation. Transplantation, 2004, Dec-15, Volume: 78, Issue:11 Topics: Acute Disease; Alkynes; Animals; Drug Therapy, Combination; Graft Rejection; Immunoglobulin M; Immunosuppressive Agents; Isoxazoles; Liver; Liver Transplantation; Male; Nitriles; Rats; Rats, Inbred BN; Rats, Inbred Lew; Tacrolimus; Transplantation, Homologous	2004
Rheumatoid arthritis complicated with acute interstitial pneumonia induced by leflunomide as an adverse reaction. Internal medicine (Tokyo, Japan), 2004, Volume: 43, Issue:12 Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Drug Eruptions; Humans; Isoxazoles; Leflunomide; Lung Diseases, Interstitial; Male; Middle Aged	2004
Severe bronchospasm after parenteral parecoxib: cyclooxygenase-2 inhibitors: not the answer yet. Anesthesiology, 2005, Volume: 102, Issue:2 Topics: Acute Disease; Adult; Aged; Bronchial Spasm; Cyclooxygenase Inhibitors; Female; Humans; Infusions, Intravenous; Injections, Intramuscular; Isoxazoles; Male	2005
FK778, a novel immunosuppressive agent, reduces early adhesion molecule up-regulation and prolongs cardiac allograft survival. Transplant international : official journal of the European Society for Organ Transplantation, 2005, Volume: 18, Issue:2 Topics: Acute Disease; Alkynes; Animals; Graft Rejection; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Intercellular Adhesion Molecule-1; Isoxazoles; Male; Nitriles; P-Selectin; Rats; Rats, Inbred BN; Rats, Inbred Lew; Transplantation, Homologous; Up-Regulation; Vascular Cell Adhesion Molecule-1	2005
COX-2 inhibitor induced anuric renal failure in a previously healthy young woman. Clinical nephrology, 2005, Volume: 63, Issue:3 Topics: Acute Disease; Acute Kidney Injury; Adult; Anuria; Cyclooxygenase Inhibitors; Female; Humans; Isoxazoles; Pyelonephritis; Sulfonamides	2005
Inhibition of cyclooxygenase-2 in experimental severe acute pancreatitis. Clinics (Sao Paulo, Brazil), 2006, Volume: 61, Issue:4 Topics: Acute Disease; Amylases; Animals; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Interleukin-10; Interleukin-6; Isoxazoles; Male; Pancreatitis; Rats; Rats, Wistar; Survival Rate; Taurocholic Acid	2006
Translocation-positive acute myeloid leukemia associated with valproic acid therapy. Pediatric blood & cancer, 2008, Volume: 50, Issue:3 Topics: Acute Disease; Anticonvulsants; Cell Differentiation; Cell Division; Child, Preschool; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 8; Clone Cells; Cocarcinogenesis; Drug Therapy, Combination; Epilepsy, Absence; Female; Humans; Isoxazoles; Lamotrigine; Leukemia, Myeloid; Levetiracetam; Neoplastic Stem Cells; Oncogene Proteins, Fusion; Phenobarbital; Piracetam; Translocation, Genetic; Triazines; Valproic Acid; Zonisamide	2008
Is the malononitrilamide FK778 better for the prevention of acute or chronic rejection? Transplantation proceedings, 2007, Volume: 39, Issue:2 Topics: Acute Disease; Alkynes; Animals; Chronic Disease; Disease Models, Animal; Graft Rejection; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Isoxazoles; Nitriles; Rats; Rats, Inbred BN; Rats, Inbred Lew; Sirolimus; Tacrolimus; Trachea; Transplantation, Homologous	2007
Risperidone treatment of refractory acute mania. The Journal of clinical psychiatry, 1995, Volume: 56, Issue:9 Topics: Acute Disease; Adult; Antipsychotic Agents; Bipolar Disorder; Female; Humans; Isoxazoles; Male; Piperidines; Risperidone; Treatment Outcome	1995
Prevention of the acute graft-versus-host disease (GVHD) in rats by the immunomodulating drug leflunomide. Annals of hematology, 1994, Volume: 68, Issue:4 Topics: Acute Disease; Animals; Conjunctivitis; Dermatitis; Graft vs Host Disease; Hybridization, Genetic; Immunosuppressive Agents; Isoxazoles; Leflunomide; Liver; Male; Rats; Rats, Inbred Lew; Spleen	1994
The role of glutamine and glucose analogues in metabolic inhibition of human myeloid leukaemia in vitro. The International journal of biochemistry, 1993, Volume: 25, Issue:12 Topics: Acute Disease; Antimetabolites, Antineoplastic; Deoxyglucose; Diazooxonorleucine; Humans; Isoxazoles; Leukemia, Myeloid; Tumor Cells, Cultured	1993
Leflunomide in experimental transplantation. Control of rejection and alloantibody production, reversal of acute rejection, and interaction with cyclosporine. Transplantation, 1994, Apr-27, Volume: 57, Issue:8 Topics: Abdomen; Acute Disease; Animals; Antibody Formation; Cyclosporine; Drug Therapy, Combination; Empyema; Graft Rejection; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Isoantibodies; Isoxazoles; Leflunomide; Male; Models, Biological; Rats; Rats, Inbred BN; Rats, Inbred Lew; Rats, Sprague-Dawley; Transplantation, Heterotopic	1994
Delayed xenograft rejection in the concordant hamster heart into Lewis rat model. Transplantation, 1996, Jul-15, Volume: 62, Issue:1 Topics: Acute Disease; Animals; Cricetinae; Cyclosporine; Drug Administration Schedule; Graft Rejection; Heart Transplantation; Immunity, Cellular; Immunosuppressive Agents; Isoxazoles; Leflunomide; Rats; Rats, Inbred Lew; Time Factors; Transplantation, Heterologous	1996
Acute skin graft rejection can be prevented and treated in rat models by malononitrilamides. Transplantation proceedings, 1996, Volume: 28, Issue:6 Topics: Acute Disease; Alkynes; Animals; Cyclosporine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Graft Rejection; Graft Survival; Immunosuppressive Agents; Isoxazoles; Nitriles; Rats; Rats, Inbred F344; Rats, Inbred Lew; Rats, Inbred Strains; Skin Transplantation; Time Factors	1996
Malononitrilamides (MNA 279 and MNA 715) have therapeutic activity in acute and chronic relapsing experimental allergic encephalomyelitis (EAE). Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1997, Volume: 46 Suppl 2 Topics: Acute Disease; Alkynes; Animals; Chronic Disease; Encephalomyelitis, Autoimmune, Experimental; Immunosuppressive Agents; Isoxazoles; Kinetics; Nitriles; Rats; Rats, Inbred Lew; Recurrence	1997
Therapeutic activity of malononitrilamides (MNA 279 and MNA 715) on acute and chronic, relapsing, experimental, allergic encephalomyelitis (EAE). Drugs under experimental and clinical research, 1997, Volume: 23, Issue:5-6 Topics: Acute Disease; Alkynes; Animals; Chronic Disease; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Guinea Pigs; Immunosuppressive Agents; Isoxazoles; Mice; Mice, Inbred Strains; Nitriles; Rabbits; Rats; Rats, Inbred Lew	1997
Hyperacute skin allograft rejection in presensitized rats is abrogated by malononitrilamides. Transplantation proceedings, 1998, Volume: 30, Issue:4 Topics: Acute Disease; Alkynes; Animals; Graft Rejection; Immunization; Immunoglobulin G; Immunoglobulin M; Immunosuppressive Agents; Isoantigens; Isoxazoles; Leflunomide; Lymphocyte Transfusion; Nitriles; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Skin Transplantation; Structure-Activity Relationship; Time Factors; Transplantation, Homologous	1998
Malononitrilamides reduce IgM and IgG xenoantibodies and prolong skin xenograft survival in a mouse-to rat model. Transplantation proceedings, 1998, Volume: 30, Issue:4 Topics: Acute Disease; Alkynes; Animals; Antibodies, Heterophile; Antibody Formation; Cyclosporine; Graft Rejection; Graft Survival; Immunosuppressive Agents; Isoxazoles; Mice; Mice, Inbred BALB C; Nitriles; Rats; Rats, Inbred Lew; Skin Transplantation; Time Factors; Transplantation, Heterologous	1998
Malononitrilamides synergistically prevent acute and treat ongoing skin allograft rejection with cyclosporine. Transplant international : official journal of the European Society for Organ Transplantation, 1998, Volume: 11 Suppl 1 Topics: Acute Disease; Alkynes; Animals; Cyclosporine; Drug Synergism; Graft Rejection; Immunosuppressive Agents; Isoxazoles; Nitriles; Rats; Rats, Inbred F344; Rats, Inbred Lew; Skin Transplantation	1998
Induction of species-specific host accommodation in the hamster-to-rat xenotransplantation model. Journal of immunology (Baltimore, Md. : 1950), 1998, Aug-15, Volume: 161, Issue:4 Topics: Acute Disease; Animals; Cricetinae; Cyclosporine; Disease Models, Animal; Drug Combinations; Graft Rejection; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Isoxazoles; Leflunomide; Mesocricetus; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Models, Biological; Rats; Rats, Inbred Lew; Species Specificity; Time Factors; Transplantation, Heterologous	1998
Efficacy and tolerability of a new antipsychotic compound (risperidone): results of a pilot study. Pharmacopsychiatry, 1991, Volume: 24, Issue:6 Topics: Acute Disease; Adult; Antipsychotic Agents; Chronic Disease; Female; Humans; Isoxazoles; Male; Middle Aged; Pilot Projects; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia	1991
Response of ammonia metabolism to acute acidosis: insights from cultured renal epithelium. American journal of kidney diseases : the official journal of the National Kidney Foundation, 1989, Volume: 14, Issue:4 Topics: Acidosis; Acute Disease; Aminooxyacetic Acid; Ammonia; Animals; Antimetabolites; Cell Line; Epithelium; Hydrogen-Ion Concentration; Isoxazoles; Kidney; Swine	1989