isotretinoin and Panic-Disorder

Isotretinoin is a drug often used in adolescents with severe acne. Several side effects of this substance, including mental disorders, have been reported. We report the case of a 17 years old patient who was diagnosed with moderate depressive episode and panic attacks in relation to the use of this product. Due to the low frequency of psychiatric adverse reactions, the prescription of isotretinoin in adolescents is clearly justified. But patients and relatives should always be properly informed, with frequent re-assessments on whether to continue with treatment. The primary care physician must take into account the influence, sometimes not detected by other specialists, of many drugs at the onset of psychiatric symptoms, such as anxiety or depression.

Topics: Acne Vulgaris; Adolescent; Depression; Dermatologic Agents; Female; Humans; Isotretinoin; Panic Disorder

The use of isotretinoin as a treatment for acne is related to psychiatric syndromes such as psychosis and depression. On the other hand, several drugs have been identified as causing panic attacks. A relationship between dermatologic and psychiatric disease has also been established. We report a 20 year-old male who started to suffer panic attacks after using isotretinoin for acne.

Topics: Acne Vulgaris; Adult; Dermatologic Agents; Humans; Isotretinoin; Male; Panic Disorder