isotretinoin has been researched along with Leukemia--Megakaryoblastic--Acute* in 1 studies
1 other study(ies) available for isotretinoin and Leukemia--Megakaryoblastic--Acute
| Article | Year |
|---|---|
Phase II study of 13-cis-retinoic acid in pediatric patients with acute nonlymphocytic leukemia--a Pediatric Oncology Group study.
Forty-one patients with refractory acute non-lymphocytic leukemia (ANLL) in relapse were treated with 13-cis-retinoic acid (cRA) as salvage therapy. The cRA was given as a single oral dose of 100 mg/m2/day for 4 weeks. One patient achieved a complete remission and two patients achieved a partial remission with reduction of the bone marrow blast count from 40 to 20% after the first course. We recommend further study of cRA in combination with other agents in the treatment of ANLL in children. Topics: Adolescent; Cell Division; Child; Child, Preschool; Drug Evaluation; Female; Humans; Infant; Isotretinoin; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Male; Remission Induction; Tumor Cells, Cultured | 1991 |