isotretinoin and Klinefelter-Syndrome

isotretinoin has been researched along with Klinefelter-Syndrome* in 3 studies

Reviews

1 review(s) available for isotretinoin and Klinefelter-Syndrome

ArticleYear
Index of suspicion.
    Pediatrics in review, 2005, Volume: 26, Issue:1

    Topics: Acne Vulgaris; Adolescent; Anti-Inflammatory Agents; Child, Preschool; Craniopharyngioma; Diagnosis, Differential; Duodenum; Female; Humans; Infant; Isotretinoin; Klinefelter Syndrome; Male; Pituitary Neoplasms; Prednisone; Prognosis; Reye Syndrome; Tomography, X-Ray Computed; Whooping Cough

2005

Other Studies

2 other study(ies) available for isotretinoin and Klinefelter-Syndrome

ArticleYear
Acne conglobata and Klinefelter's syndrome.
    The British journal of dermatology, 1997, Volume: 136, Issue:3

    Acne conglobata has been reported to be more common and more severe in XYY chromosomal aberration than in normal subjects. Whereas only exceptional cases have been observed in the more common XXY Klinefelter karyotype. We report a 17-year-old male with both Klinefelter's syndrome and acne conglobata, spreading from face to upper arms, trunk, buttocks and upper legs. The serum level of testosterone was normal, whereas luteinizing hormone and follicle-stimulating hormone were elevated. Skin lesions responded well to a combined therapeutic regimen including oral isotretinoin and prednisolone. An overview of severe acne in relation to chromosomal abnormalities is given and diagnostic and therapeutic options discussed.

    Topics: Acne Vulgaris; Adolescent; Anti-Inflammatory Agents; Drug Therapy, Combination; Humans; Isotretinoin; Karyotyping; Keratolytic Agents; Klinefelter Syndrome; Male; Prednisolone

1997
[Fulminant acne in Klinefelter syndrome treated with testosterone. A side effect of anti-tallness therapy].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1989, Volume: 137, Issue:8

    Acne lesions usually do not occur in patients with Klinefelter's syndrome (47 XXXY). But a 19 year old patient with Klinefelter's syndrome, under therapy with testosteronenantat (500 mg every two weeks over a period of 18 months) for treatment of excessively tall stature developed acne fulminans. Following discontinuation of testosterone treatment and isotretinoin therapy over 16 weeks skin lesions healed almost completely although with severe scars. In conclusion, high doses testosterone-treatment in excessively tall boys needs the additional care of dermatologist when mostly after a 7 months period acne begins to develop under this treatment.

    Topics: Acne Vulgaris; Adult; Body Height; Gigantism; Gonadal Steroid Hormones; Humans; Isotretinoin; Klinefelter Syndrome; Male; Sexual Maturation; Testosterone

1989