isotretinoin and Arthritis--Rheumatoid

Isotretinoin is used for the treatment of various acne lesions that are resistant to other treatments. The most frequent rheumatologic side effect of isotretinoin is transient muscle and/or joint pains. Here, we report a case with bilateral wrist and metacarpophalangeal joint arthritis and unilateral sacroiliitis associated with isotretinoin usage to attract attention, particularly from physiatrists, rheumatologists and dermatologists, to this rare adverse effect of isotretinoin.

Topics: Acne Vulgaris; Arthritis, Rheumatoid; Diagnosis, Differential; Follow-Up Studies; Humans; Isotretinoin; Magnetic Resonance Imaging; Male; Pain Measurement; Range of Motion, Articular; Risk Assessment; Sacroiliitis; Severity of Illness Index; Spondylarthritis; Young Adult

Topics: Adalimumab; Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis, Rheumatoid; Dermatologic Agents; Etanercept; Female; Flurandrenolone; Foot; Hand; Humans; Immunoglobulin G; Isotretinoin; Keratolytic Agents; Methotrexate; Middle Aged; Prednisone; Psoriasis; Receptors, Tumor Necrosis Factor; Skin; Tumor Necrosis Factor-alpha

Topics: Arthritis, Rheumatoid; Cells, Cultured; Humans; Isotretinoin; L-Lactate Dehydrogenase; Microbial Collagenase; Prostaglandins E; Synovial Membrane; Tretinoin; Vitamin A