Page last updated: 2024-08-23

isosorbide-5-mononitrate and Liver Cirrhosis

isosorbide-5-mononitrate has been researched along with Liver Cirrhosis in 63 studies

Research

Studies (63)

TimeframeStudies, this research(%)All Research%
pre-19905 (7.94)18.7374
1990's23 (36.51)18.2507
2000's28 (44.44)29.6817
2010's7 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, SL; Chen, YP; Fan, YC; Ling, XF; Liu, WY; Pan, ZZ; Shi, KQ; Zheng, MH1
Aracil, C; Colomo, A; Gich, I; Graupera, I; Guarner, C; Hernández-Gea, V; Poca, M; Puente, A; Roque, M; Villanueva, C1
Appenrodt, B; Caca, K; Dollinger, M; Fimmers, R; Hoffmeister, A; Lorenzen, H; Lutz, H; Mengel, M; Panther, E; Rössle, M; Sauerbruch, T; Schepke, M; Schoo, R; Trebicka, J; Wiest, R; Zipprich, A1
Alvarado, E; Aracil, C; Ardevol, A; Colomo, A; Concepción, M; Graupera, I; Guarner, C; Hernandez-Gea, V; Miñana, J; Pavel, O; Poca, M; Puente, Á; Reñe, JM; Torras, X; Villanueva, C1
Aracil, C; Balanzo, J; Colomo, A; Gonzalez, B; Guarner, C; Lopez-Balaguer, JM; Piqueras, M; Torras, X; Villanueva, C1
Kumar, A; Sarin, SK; Sharma, BC; Sharma, P1
Ding, SH; Liu, J; Wang, JP1
Jo, YJ; Jun, DW; Kang, JS; Kim, EK; Kim, KT; Kim, SH; Park, JH; Park, YS; Son, BK1
Schepke, M1
Li, L; Li, Y; Yu, C1
Abu-Suboh, M; Armengol, JR; Augustin, S; Dot, J; Esteban, R; Genescà, J; González, A; Guardia, J; Pérez, M; Romero, A; Segarra, A1
Bissoli, F; Borroni, G; Cazzaniga, M; de Franchis, R; Lorenzano, E; Maggi, A; Panzeri, A; Salerno, F; Visentin, S1
Burroughs, AK; Gerunda, G; Goulis, J; Greenslade, L; Merkel, C; Patch, D; Sabin, CA1
Wang, H; Yuan, R; Zhang, Q1
Abraldes, JG; Bellis, L; Berzigotti, A; Bosch, J; García-Pagán, JC; Moitinho, E; Rodés, J1
Abraldes, JG; Bosch, J; Garcia-Pagan, JC; Rodés, J; Tarantino, I; Turnes, J1
Aracil, C; Balanzó, J; González, B; Guarner, C; Kolle, L; López-Balaguer, JM; Miñana, J; Soriano, G; Villanueva, C1
Bhaskar, ME1
Hou, MC; Huang, YT; Lee, FY; Lee, SD; Lin, HC; Yang, YY1
Geĭnits, AV; Sapozhkova, LP; Sergienko, VB; Tadzhiev, IIa; Tadzhieva, NI; Topchiashvili, ZA; Tsodikov, GV1
Bolondi, L; Donati, G; Gaiani, S; Gramantieri, L; Leoni, S; Mancini, M; Piscaglia, F1
Balas, BI; Diculescu, M; Orban Schiopu, AM1
Chen, MX; Lin, XF; Lin, XY; Wu, JM; Wu, XL; Zhu, QH1
Gupta, R; Sarin, SK; Shahi, H; Wadhawan, M1
Argonz, J; Bosco, A; Dominguez, N; Fassio, E; Kravetz, D; Muñoz, A; Romero, G; Salgado, P; Suarez, A; Terg, R; Vulcano, C1
Laleman, W; Nevens, F1
Chan, HH; Chen, WC; Cheng, LC; Hsu, PI; Lai, KH; Lo, GH; Tsai, WL; Wang, HM1
Bosch, J; De Gottardi, A; Garcia-Pagan, JC1
Steudel, AT; Steudel, HC; Volkenandt, M1
Amodio, P; Angeli, P; Cavallarin, G; Donada, C; Enzo, E; Gatta, A; Marin, R; Merkel, C; Sebastianelli, G; Torboli, P1
Bellon, S; Bolognesi, M; Caregaro, L; Gatta, A; Merkel, C; Sacerdoti, D1
Bolognesi, M; Gatta, A; Merkel, C; Sacerdoti, D1
Bangash, IH; Finlayson, ND; Hayes, PC; Jones, AL; Simpson, KJ; Walker, J1
Bosch, J; Cabré, E; Feu, F; Galán, A; García Pagán, JC; Gassull, MA; Morillas, RM; Planas, R; Quer, JC1
Bouchier, IA; Grose, RD; Hayes, PC; Plevris, JN; Redhead, DN1
Abbati, G; Cioni, G; Cristani, A; D'Alimonte, P; Romagnoli, R; Tincani, E; Ventura, E; Ventura, P; Vignoli, A1
Hayes, PC; Jones, AL1
Angelico, M; Bologna, E; Capocaccia, L; Carli, L; Gentile, S; Piat, C; Rinaldi, V1
Arroyo, V; Bosch, J; Claria, J; Feu, F; García-Pagán, JC; Ginès, A; Ginès, P; Rivera, F; Ruiz del Arbol, L; Salmerón, JM1
Bissoli, F; Borroni, G; Cazzaniga, M; Ceriani, R; deFranchis, R; Lorenzano, E; Salerno, F; Solenghi, D1
Bordas, JM; Bosch, J; Escorsell, A; Feu, F; García-Pagán, JC; Luca, A; Rodés, J1
Angeli, P; Bolognesi, M; Bombonato, G; Enzo, E; Gatta, A; Marin, R; Merkel, C; Sacerdoti, D1
Angelico, M; Capocaccia, L; Carli, L; Gentile, S; Piat, C1
Bordas, JM; Bosch, J; Escorsell, A; Feu, F; García-Pagán, JC; Ginès, A; Rodés, J1
Bouchier, IA; Hayes, PC; Stanley, AJ1
Bolognesi, M; Bombonato, G; Gatta, A; Merkel, C; Sacerdoti, D1
Bolondi, L; Gaiani, S; Gramantieri, L; Piscaglia, F; Serra, C; Siringo, S1
Burroughs, AK; Chin, J; Greenslade, L; McCormick, PA; McIntyre, N; Patch, D1
Amodio, P; Angeli, P; Bolognesi, M; Buonamico, P; Gatta, A; Merkel, C; Micotti, L; Sacerdoti, D; Sticca, A1
Amodio, P; Bolognesi, M; Cavallarin, G; Donada, C; Felder, M; Gatta, A; Marin, R; Mazzaro, C; Merkel, C; Sacerdoti, D; Sebastianelli, G; Torboli, P1
Bellini, B; Bighin, R; Bolognesi, M; Bombonato, G; Gatta, A; Merkel, C; Sacerdoti, D1
Herrera, JL; Zalepuga, R1
Chen, SD; Hsieh, JF; Lin, WY; Tsai, SC1
Abdurakhmanov, DT1
Albillos, A; Balanzó, J; Bosch, J; Calleja, JL; García-Pagán, JC; Genescà, J; González, A; Planas, R; Rodriguez, M; Ruiz-Del-Arbol, L; Solà, R; Vila, MC; Villanueva, C1
Bañares, R; Bosch, J; Bru, C; Echenagusia, A; Escorsell, A; García-Pagán, JC; Gilabert, R; Granados, A; Moitinho, E; Piqueras, B1
Bosch, J; Feu, F; García-Pagán, JC; Rodés, J1
Bosch, J; Bru, C; Feu, F; García-Pagán, JC; Navasa, M; Rodés, J; Ruiz del Arbol, L1
Bosch, J; Bru, C; Garcia-Pagán, JC; Navasa, M; Pizcueta, P; Rodés, J1
Chang, TT; Kong, CW; Lay, CS; Lee, FY; Lee, SD; Lin, HC; Lo, KJ; Tsai, YT; Wang, SS1
Bosch, J; Chesta, J; Navasa, M; Rodés, J1
Hayes, PC; Westaby, D; Williams, R1
Kanto, JH1

Reviews

8 review(s) available for isosorbide-5-mononitrate and Liver Cirrhosis

ArticleYear
Secondary prophylaxis of variceal bleeding for cirrhotic patients: a multiple-treatments meta-analysis.
    European journal of clinical investigation, 2013, Volume: 43, Issue:8

    Topics: Adrenergic beta-Antagonists; Combined Modality Therapy; Endoscopy, Gastrointestinal; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Isosorbide Dinitrate; Laser Coagulation; Ligation; Liver Cirrhosis; Portasystemic Shunt, Transjugular Intrahepatic; Randomized Controlled Trials as Topic; Sclerotherapy; Secondary Prevention; Treatment Outcome; Vasodilator Agents

2013
Drugs plus ligation to prevent rebleeding in cirrhosis: an updated systematic review.
    Liver international : official journal of the International Association for the Study of the Liver, 2014, Volume: 34, Issue:6

    Topics: Adrenergic beta-Antagonists; Animals; Chi-Square Distribution; Combined Modality Therapy; Drug Therapy, Combination; Endoscopy, Gastrointestinal; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hemostatic Techniques; Hemostatics; Humans; Isosorbide Dinitrate; Ligation; Liver Cirrhosis; Odds Ratio; Recurrence; Risk Factors; Treatment Outcome

2014
Efficacy of beta-adrenergic blocker plus 5-isosorbide mononitrate and endoscopic band ligation for prophylaxis of esophageal variceal rebleeding: a meta-analysis.
    World journal of gastroenterology, 2009, May-07, Volume: 15, Issue:17

    Topics: Adrenergic beta-Antagonists; Endoscopy; Esophageal and Gastric Varices; Humans; Isosorbide Dinitrate; Ligation; Liver Cirrhosis; Randomized Controlled Trials as Topic; Treatment Outcome; Vasodilator Agents

2009
[Importance of drug treatment to lower portal pressure in the therapy of variceal bleeding].
    Deutsche medizinische Wochenschrift (1946), 2009, Volume: 134, Issue:37

    Topics: Adrenergic beta-Antagonists; Anti-Bacterial Agents; Drug Therapy, Combination; Esophageal and Gastric Varices; Esophagoscopy; Gastrointestinal Hemorrhage; Hormones; Humans; Hypertension, Portal; Infection Control; Isosorbide Dinitrate; Ligation; Liver Cirrhosis; Lypressin; Portal Pressure; Secondary Prevention; Somatostatin; Terlipressin; Vasoconstrictor Agents; Vasodilator Agents

2009
Endoscopic band ligation versus pharmacological therapy for variceal bleeding in cirrhosis: a meta-analysis.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2011, Volume: 25, Issue:3

    Topics: Adrenergic beta-Antagonists; Comparative Effectiveness Research; Endoscopy; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Isosorbide Dinitrate; Ligation; Liver Cirrhosis; Primary Prevention; Randomized Controlled Trials as Topic; Risk Factors; Secondary Prevention; Treatment Outcome; Vasodilator Agents

2011
Cirrhotic portal hypertension: current and future medical therapy for primary and secondary prevention of variceal bleeding.
    Minerva medica, 2006, Volume: 97, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Contraindications; Drug Therapy, Combination; Endoscopy; Esophageal and Gastric Varices; Follow-Up Studies; Forecasting; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Isosorbide Dinitrate; Ligation; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Middle Aged; Nadolol; Portasystemic Shunt, Surgical; Portasystemic Shunt, Transjugular Intrahepatic; Practice Guidelines as Topic; Propranolol; Randomized Controlled Trials as Topic; Rats; Risk Factors; Risk Reduction Behavior; Splanchnic Circulation; Stents; Time Factors; Vascular Resistance; Vasodilator Agents

2006
Review article: the modern management of portal hypertension--primary and secondary prophylaxis of variceal bleeding in cirrhotic patients.
    Alimentary pharmacology & therapeutics, 2008, Volume: 28, Issue:2

    Topics: Adrenergic beta-Antagonists; Drug Therapy, Combination; Esophageal and Gastric Varices; Humans; Hypertension, Portal; Isosorbide Dinitrate; Ligation; Liver Cirrhosis; Randomized Controlled Trials as Topic; Sclerotherapy; Secondary Prevention; Treatment Outcome

2008
Organic nitrates in portal hypertension.
    The American journal of gastroenterology, 1994, Volume: 89, Issue:1

    Topics: Animals; Collateral Circulation; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Isosorbide Dinitrate; Liver Circulation; Liver Cirrhosis; Nitrates; Nitroglycerin; Vasodilator Agents

1994

Trials

37 trial(s) available for isosorbide-5-mononitrate and Liver Cirrhosis

ArticleYear
Prevention of Rebleeding From Esophageal Varices in Patients With Cirrhosis Receiving Small-Diameter Stents Versus Hemodynamically Controlled Medical Therapy.
    Gastroenterology, 2015, Volume: 149, Issue:3

    Topics: Adrenergic beta-Antagonists; Drug Therapy, Combination; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Germany; Humans; Isosorbide Dinitrate; Kaplan-Meier Estimate; Liver Cirrhosis; Male; Middle Aged; Nitric Oxide Donors; Portasystemic Shunt, Transjugular Intrahepatic; Propranolol; Prospective Studies; Prosthesis Design; Quality of Life; Recurrence; Stents; Time Factors; Treatment Outcome; Vasodilator Agents; Venous Pressure

2015
A randomized trial to assess whether portal pressure guided therapy to prevent variceal rebleeding improves survival in cirrhosis.
    Hepatology (Baltimore, Md.), 2017, Volume: 65, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Drug Therapy, Combination; Endoscopy, Gastrointestinal; Female; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Isosorbide Dinitrate; Liver Cirrhosis; Male; Middle Aged; Portal Pressure; Recurrence; Spain

2017
Clinical trial: a randomized controlled study on prevention of variceal rebleeding comparing nadolol + ligation vs. hepatic venous pressure gradient-guided pharmacological therapy.
    Alimentary pharmacology & therapeutics, 2009, Feb-15, Volume: 29, Issue:4

    Topics: Antihypertensive Agents; Drug Therapy, Combination; Esophageal and Gastric Varices; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Hemodynamics; Humans; Isosorbide Dinitrate; Ligation; Liver Cirrhosis; Male; Middle Aged; Nadolol; Secondary Prevention; Venous Pressure

2009
Adding banding ligation is effective as rescue therapy to prevent variceal rebleeding in haemodynamic non-responders to pharmacological therapy.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2012, Volume: 44, Issue:1

    Topics: Acute Disease; Aged; Esophageal and Gastric Varices; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; Isosorbide Dinitrate; Ligation; Liver Cirrhosis; Male; Middle Aged; Nadolol; Secondary Prevention; Somatostatin; Treatment Outcome

2012
Nadolol is superior to isosorbide mononitrate for the prevention of the first variceal bleeding in cirrhotic patients with ascites.
    Journal of hepatology, 2002, Volume: 37, Issue:3

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Blood Pressure; Esophageal and Gastric Varices; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Heart Rate; Humans; Isosorbide Dinitrate; Kidney; Liver Cirrhosis; Male; Middle Aged; Nadolol; Survival Rate; Treatment Outcome; Vasodilator Agents

2002
A randomized, controlled trial of medical therapy versus endoscopic ligation for the prevention of variceal rebleeding in patients with cirrhosis.
    Gastroenterology, 2002, Volume: 123, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Endoscopy; Esophageal and Gastric Varices; Female; Follow-Up Studies; Humans; Isosorbide Dinitrate; Ligation; Liver Cirrhosis; Male; Middle Aged; Propranolol; Secondary Prevention; Vasodilator Agents; Venous Pressure

2002
[The randomized controlled trial of isosorbide mononitrate plus propranolol compared with propranolol alone for the prevention of variceal rebleeding].
    Zhonghua yi xue za zhi, 2002, Sep-10, Volume: 82, Issue:17

    Topics: Adult; Dizziness; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Headache; Humans; Isosorbide Dinitrate; Liver Cirrhosis; Male; Middle Aged; Propranolol; Treatment Outcome; Vasodilator Agents

2002
Low doses of isosorbide mononitrate attenuate the postprandial increase in portal pressure in patients with cirrhosis.
    Hepatology (Baltimore, Md.), 2003, Volume: 37, Issue:2

    Topics: Aged; Blood Pressure; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Isosorbide Dinitrate; Liver Cirrhosis; Male; Middle Aged; Nitric Oxide Donors; Portal Vein; Postprandial Period; Propranolol; Vasodilator Agents

2003
Maintenance of hemodynamic response to treatment for portal hypertension and influence on complications of cirrhosis.
    Journal of hepatology, 2004, Volume: 40, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Ascites; Esophageal and Gastric Varices; Female; Hemodynamics; Hepatic Encephalopathy; Humans; Hypertension, Portal; Isosorbide Dinitrate; Liver Circulation; Liver Cirrhosis; Liver Transplantation; Male; Middle Aged; Nadolol; Prognosis

2004
Acute administration of carvedilol is more effective than propranolol plus isosorbide-5-mononitrate in the reduction of portal pressure in patients with viral cirrhosis.
    The American journal of gastroenterology, 2004, Volume: 99, Issue:10

    Topics: Antihypertensive Agents; Carbazoles; Carvedilol; Drug Therapy, Combination; Female; Humans; Hypertension, Portal; Isosorbide Dinitrate; Liver Cirrhosis; Male; Middle Aged; Propanolamines; Propranolol; Vasodilator Agents

2004
[Comparative effectiveness of different methods of diagnosis and correction of impaired portal circulation].
    Klinicheskaia meditsina, 2004, Volume: 82, Issue:7

    Topics: Antihypertensive Agents; Humans; Hypertension, Portal; Isosorbide Dinitrate; Laser Therapy; Liver Cirrhosis; Propranolol; Ultrasonography, Doppler; Vasodilator Agents

2004
Different haemodynamic effects of a single dose of long-acting isosorbide-5-mononitrate in healthy subjects and patients with cirrhotic portal hypertension.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2004, Volume: 36, Issue:9

    Topics: Aged; Blood Flow Velocity; Double-Blind Method; Fasting; Female; Humans; Hypertension, Portal; Isosorbide Dinitrate; Liver Cirrhosis; Male; Middle Aged; Portal Pressure; Portal Vein; Time Factors; Treatment Outcome; Vasodilator Agents

2004
[Effects of isosorbide-5-mononitrate on esophageal manometry of cirrhotic patients with esophageal varices].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2005, Volume: 13, Issue:8

    Topics: Adult; Esophageal and Gastric Varices; Esophagus; Female; Humans; Isosorbide Dinitrate; Liver Cirrhosis; Male; Manometry; Vasodilator Agents

2005
Evaluation of endoscopic variceal ligation (EVL) versus propanolol plus isosorbide mononitrate/nadolol (ISMN) in the prevention of variceal rebleeding: comparison of cirrhotic and noncirrhotic patients.
    Digestive diseases and sciences, 2005, Volume: 50, Issue:8

    Topics: Adult; Antihypertensive Agents; Drug Therapy, Combination; Endoscopy, Digestive System; Esophageal and Gastric Varices; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; Isosorbide Dinitrate; Ligation; Liver Cirrhosis; Male; Middle Aged; Nadolol; Propranolol; Secondary Prevention; Vasodilator Agents

2005
Comparative study between nadolol and 5-isosorbide mononitrate vs. endoscopic band ligation plus sclerotherapy in the prevention of variceal rebleeding in cirrhotic patients: a randomized controlled trial.
    Alimentary pharmacology & therapeutics, 2006, Aug-15, Volume: 24, Issue:4

    Topics: Endoscopy, Gastrointestinal; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Humans; Isosorbide Dinitrate; Ligation; Liver Cirrhosis; Male; Middle Aged; Nadolol; Sclerotherapy; Secondary Prevention

2006
Comparison of endoscopic variceal ligation and nadolol plus isosorbide-5-mononitrate in the prevention of first variceal bleeding in cirrhotic patients.
    Journal of the Chinese Medical Association : JCMA, 2006, Volume: 69, Issue:10

    Topics: Adult; Aged; Drug Therapy, Combination; Endoscopy, Gastrointestinal; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Humans; Isosorbide Dinitrate; Ligation; Liver Cirrhosis; Male; Middle Aged; Nadolol

2006
Long-term effect of nadolol or nadolol plus isosorbide-5-mononitrate on renal function and ascites formation in patients with cirrhosis. GTIP Gruppo Triveneto per l'Ipertensione Portale.
    Hepatology (Baltimore, Md.), 1995, Volume: 22, Issue:3

    Topics: Adolescent; Adult; Aged; Ascites; Drug Therapy, Combination; Esophageal and Gastric Varices; Female; Humans; Isosorbide Dinitrate; Kidney; Liver Cirrhosis; Longitudinal Studies; Male; Middle Aged; Nadolol; Venous Pressure

1995
Duplex Doppler ultrasonography allows a multiorgan noninvasive approach to splanchnic pharmacodynamics in patients with cirrhosis.
    Bildgebung = Imaging, 1995, Volume: 62, Issue:2

    Topics: Administration, Oral; Adult; Aged; Blood Flow Velocity; Blood Pressure; Drug Therapy, Combination; Esophageal and Gastric Varices; Female; Hemodynamics; Humans; Hypertension, Portal; Isosorbide Dinitrate; Kidney; Liver; Liver Cirrhosis; Male; Mesenteric Artery, Superior; Middle Aged; Nadolol; Pulsatile Flow; Splanchnic Circulation; Ultrasonography, Doppler, Color; Vascular Resistance; Vasodilator Agents

1995
Duplex Doppler sonographic evaluation of splanchnic and renal effects of single agent and combined therapy with nadolol and isosorbide-5-mononitrate in cirrhotic patients.
    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 1994, Volume: 13, Issue:12

    Topics: Adult; Drug Therapy, Combination; Esophageal and Gastric Varices; Female; Humans; Hypertension, Portal; Isosorbide Dinitrate; Liver Cirrhosis; Male; Middle Aged; Nadolol; Renal Circulation; Splanchnic Circulation; Ultrasonography, Doppler, Duplex; Vasodilator Agents

1994
Portal and systemic haemodynamic response to acute and chronic administration of low and high dose isosorbide-5-mononitrate in patients with cirrhosis.
    Gut, 1995, Volume: 36, Issue:1

    Topics: Adult; Aged; Azygos Vein; Blood Pressure; Dose-Response Relationship, Drug; Drug Administration Schedule; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Heart Rate; Hemodynamics; Humans; Isosorbide Dinitrate; Liver Circulation; Liver Cirrhosis; Male; Middle Aged; Patient Compliance; Regional Blood Flow; Stimulation, Chemical; Vasodilator Agents

1995
Propranolol plus isosorbide-5-mononitrate for portal hypertension in cirrhosis: long-term hemodynamic and renal effects.
    Hepatology (Baltimore, Md.), 1994, Volume: 20, Issue:6

    Topics: Aldosterone; Analysis of Variance; Body Water; Chi-Square Distribution; Dinoprostone; Drug Therapy, Combination; Female; Follow-Up Studies; Hemodynamics; Humans; Hypertension, Portal; Inulin; Isosorbide Dinitrate; Kidney; Liver Cirrhosis; Male; Middle Aged; Portal Pressure; Propranolol; Renin; Splanchnic Circulation; Vasodilator Agents

1994
Duplex Doppler ultrasonographic comparison of the effects of propranolol and isosorbide-5-mononitrate on portal hemodynamics.
    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 1993, Volume: 12, Issue:9

    Topics: Delayed-Action Preparations; Double-Blind Method; Drug Monitoring; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Hemodynamics; Humans; Hypertension, Portal; Isosorbide Dinitrate; Liver Cirrhosis; Male; Middle Aged; Propranolol; Splanchnic Circulation; Ultrasonography

1993
Isosorbide-5-mononitrate versus propranolol in the prevention of first bleeding in cirrhosis.
    Gastroenterology, 1993, Volume: 104, Issue:5

    Topics: Aged; Digestive System; Endoscopy; Female; Gastrointestinal Hemorrhage; Humans; Isosorbide Dinitrate; Liver Cirrhosis; Male; Middle Aged; Patient Dropouts; Personnel Selection; Propranolol; Prospective Studies

1993
Effects of isosorbide-5-mononitrate on variceal pressure and systemic and splanchnic haemodynamics in patients with cirrhosis.
    Journal of hepatology, 1996, Volume: 24, Issue:4

    Topics: Aged; Blood Pressure; Double-Blind Method; Esophageal and Gastric Varices; Female; Hemodynamics; Humans; Hypertension, Portal; Isosorbide Dinitrate; Liver Circulation; Liver Cirrhosis; Male; Middle Aged; Splanchnic Circulation; Vasodilator Agents; Venous Pressure

1996
Hemodynamic evaluation of the addition of isosorbide-5-mononitrate to nadolol in cirrhotic patients with insufficient response to the beta-blocker alone.
    Hepatology (Baltimore, Md.), 1997, Volume: 26, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Female; Heart Rate; Hemodynamics; Hepatic Artery; Humans; Hypertension, Portal; Isosorbide Dinitrate; Liver; Liver Cirrhosis; Male; Middle Aged; Nadolol; Vasodilator Agents

1997
Effects of isosorbide-5-mononitrate compared with propranolol on first bleeding and long-term survival in cirrhosis.
    Gastroenterology, 1997, Volume: 113, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; Isosorbide Dinitrate; Liver Cirrhosis; Male; Middle Aged; Propranolol; Single-Blind Method; Vasodilator Agents

1997
Endoscopic assessment of variceal volume and wall tension in cirrhotic patients: effects of pharmacological therapy.
    Gastroenterology, 1997, Volume: 113, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Double-Blind Method; Endosonography; Esophageal and Gastric Varices; Female; Hemodynamics; Humans; Isosorbide Dinitrate; Liver Cirrhosis; Male; Middle Aged; Propranolol; Vasodilator Agents

1997
Doppler sonography and hepatic vein catheterization in portal hypertension: assessment of agreement in evaluating severity and response to treatment.
    Journal of hepatology, 1998, Volume: 28, Issue:4

    Topics: Adrenergic beta-Antagonists; Catheterization, Peripheral; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Hepatic Veins; Humans; Hypertension, Portal; Isosorbide Dinitrate; Linear Models; Liver Cirrhosis; Male; Middle Aged; Nadolol; Treatment Outcome; Ultrasonography, Doppler, Duplex; Vasodilator Agents

1998
Duplex-Doppler evaluation of the effects of propranolol and isosorbide-5-mononitrate on portal flow and splanchnic arterial circulation in cirrhosis.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Esophageal and Gastric Varices; Female; Humans; Isosorbide Dinitrate; Liver Cirrhosis; Male; Middle Aged; Portal System; Propranolol; Splanchnic Circulation; Ultrasonography, Doppler, Duplex; Vasodilator Agents

1998
Long-term results of a clinical trial of nadolol with or without isosorbide mononitrate for primary prophylaxis of variceal bleeding in cirrhosis.
    Hepatology (Baltimore, Md.), 2000, Volume: 31, Issue:2

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Drug Therapy, Combination; Esophageal and Gastric Varices; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Isosorbide Dinitrate; Liver Cirrhosis; Male; Middle Aged; Nadolol; Randomized Controlled Trials as Topic

2000
Should nitrates be used with beta blockers to prevent variceal bleeding?
    The American journal of gastroenterology, 2000, Volume: 95, Issue:10

    Topics: Adrenergic beta-Antagonists; Drug Therapy, Combination; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Isosorbide Dinitrate; Liver Cirrhosis; Nadolol; Vasodilator Agents

2000
Isosorbide mononitrate in the prevention of first variceal bleed in patients who cannot receive beta-blockers.
    Gastroenterology, 2001, Volume: 121, Issue:4

    Topics: Adrenergic beta-Antagonists; Ascites; Contraindications; Double-Blind Method; Female; Gastroesophageal Reflux; Hemodynamics; Humans; Isosorbide Dinitrate; Kidney Function Tests; Liver Cirrhosis; Male; Middle Aged; Odds Ratio; Patient Selection; Probability; Prothrombin Time; Survival Rate

2001
TIPS versus drug therapy in preventing variceal rebleeding in advanced cirrhosis: a randomized controlled trial.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Drug Therapy, Combination; Female; Follow-Up Studies; Health Care Costs; Hemorrhage; Hepatic Encephalopathy; Humans; Isosorbide Dinitrate; Liver; Liver Cirrhosis; Male; Middle Aged; Portasystemic Shunt, Transjugular Intrahepatic; Propranolol; Prospective Studies; Quality of Life; Retreatment; Secondary Prevention; Varicose Veins

2002
Propranolol compared with propranolol plus isosorbide-5-mononitrate for portal hypertension in cirrhosis. A randomized controlled study.
    Annals of internal medicine, 1991, May-15, Volume: 114, Issue:10

    Topics: Aged; Drug Therapy, Combination; Female; Hemodynamics; Hepatic Veins; Humans; Hypertension, Portal; Isosorbide Dinitrate; Liver; Liver Circulation; Liver Cirrhosis; Male; Middle Aged; Propranolol; Venous Pressure

1991
Long-term haemodynamic effects of isosorbide 5-mononitrate in patients with cirrhosis and portal hypertension.
    Journal of hepatology, 1990, Volume: 11, Issue:2

    Topics: Administration, Oral; Aged; Blood Pressure; Double-Blind Method; Female; Hemodynamics; Humans; Hypertension, Portal; Isosorbide Dinitrate; Liver; Liver Cirrhosis; Male; Middle Aged; Nitroglycerin; Placebos; Time Factors

1990
Lack of effects of isosorbide-5-mononitrate on hepatic hemodynamics in HBsAg-positive cirrhosis.
    Hepatology (Baltimore, Md.), 1989, Volume: 10, Issue:3

    Topics: Aged; Blood Pressure; Drug Administration Schedule; Hemodynamics; Hepatitis B Surface Antigens; Humans; Isosorbide Dinitrate; Liver Circulation; Liver Cirrhosis; Male; Middle Aged; Portal Vein; Random Allocation

1989
Reduction of portal pressure by isosorbide-5-mononitrate in patients with cirrhosis. Effects on splanchnic and systemic hemodynamics and liver function.
    Gastroenterology, 1989, Volume: 96, Issue:4

    Topics: Adult; Aged; Female; Hemodynamics; Humans; Hypertension, Portal; Isosorbide Dinitrate; Liver; Liver Cirrhosis; Male; Middle Aged; Splanchnic Circulation

1989

Other Studies

18 other study(ies) available for isosorbide-5-mononitrate and Liver Cirrhosis

ArticleYear
Early identification of haemodynamic response to pharmacotherapy is essential for primary prophylaxis of variceal bleeding in patients with 'high-risk' varices.
    Alimentary pharmacology & therapeutics, 2009, Volume: 30, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Esophageal and Gastric Varices; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Hemodynamics; Humans; Isosorbide Dinitrate; Liver Cirrhosis; Male; Middle Aged; Propranolol; Risk Factors; Treatment Outcome; Vasodilator Agents; Young Adult

2009
The role of nitric oxide in the expression of renal aquaporin 2 in a cirrhotic rat model: does an AVP-independent mechanism exist for the regulation of AQP2 expression?
    Digestive diseases and sciences, 2010, Volume: 55, Issue:5

    Topics: Analysis of Variance; Animals; Aquaporin 2; Biopterins; Cyclic GMP; Disease Models, Animal; Immunoenzyme Techniques; Isosorbide Dinitrate; Kidney; Liver Cirrhosis; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Random Allocation; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Simvastatin; Statistics, Nonparametric; Thioacetamide

2010
Hemodynamic response to pharmacological treatment of portal hypertension and long-term prognosis of cirrhosis.
    Hepatology (Baltimore, Md.), 2003, Volume: 37, Issue:4

    Topics: Antihypertensive Agents; Ascites; Bacterial Infections; Cohort Studies; Drug Therapy, Combination; Female; Hemodynamics; Hemorrhage; Hepatic Encephalopathy; Hepatorenal Syndrome; Humans; Hypertension, Portal; Isosorbide Dinitrate; Liver Cirrhosis; Male; Middle Aged; Peritonitis; Probability; Prognosis; Propranolol; Recurrence; Risk Factors; Survival Analysis; Time Factors; Varicose Veins; Vasodilator Agents

2003
Management of cirrhosis and ascites.
    The New England journal of medicine, 2004, Jul-15, Volume: 351, Issue:3

    Topics: Adrenergic beta-Antagonists; Drug Therapy, Combination; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Isosorbide Dinitrate; Liver Cirrhosis; Nadolol; Propranolol; Secondary Prevention; Vasodilator Agents

2004
The effect of a combined treatment with propranolol and isosorbide-5-mononitrate on Doppler ultrasound parameters in patients with cirrhosis and portal hypertension.
    Romanian journal of gastroenterology, 2005, Volume: 14, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Blood Flow Velocity; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypertension, Portal; Isosorbide Dinitrate; Liver Cirrhosis; Male; Portal Vein; Propranolol; Prospective Studies; Treatment Outcome; Ultrasonography, Doppler; Vasodilator Agents

2005
Pharmacokinetics of isosorbide-5-mononitrate after oral and intravenous administration in patients with liver cirrhosis: first results.
    Zeitschrift fur Kardiologie, 1983, Volume: 72 Suppl 3

    Topics: Administration, Oral; Adult; Female; Humans; Infusions, Parenteral; Isosorbide Dinitrate; Kinetics; Liver Cirrhosis; Male; Middle Aged

1983
The acute and chronic effects of isosorbide-5-mononitrate on portal haemodynamics in cirrhosis.
    Journal of hepatology, 1994, Volume: 20, Issue:4

    Topics: Adult; Aged; Azygos Vein; Hemodynamics; Humans; Hypertension, Portal; Isosorbide Dinitrate; Liver Cirrhosis; Middle Aged; Vasodilator Agents

1994
Renal effects of acute isosorbide-5-mononitrate administration in cirrhosis.
    Hepatology (Baltimore, Md.), 1993, Volume: 17, Issue:5

    Topics: Aldosterone; Ascites; Atrial Natriuretic Factor; Hemodynamics; Humans; Hypertension, Portal; Isosorbide Dinitrate; Kidney; Liver Cirrhosis; Renin

1993
Long-term administration of isosorbide-5-mononitrate does not impair renal function in cirrhotic patients.
    Hepatology (Baltimore, Md.), 1996, Volume: 23, Issue:5

    Topics: Ascites; Atrial Natriuretic Factor; Blood Pressure; Drug Administration Schedule; Female; Glomerular Filtration Rate; Humans; Isosorbide Dinitrate; Kidney; Liver Cirrhosis; Male; Middle Aged; Natriuresis; Potassium; Renal Plasma Flow; Renin; Vasodilator Agents

1996
Acute effect of propranolol and isosorbide-5-mononitrate administration on renal blood flow in cirrhotic patients.
    Gut, 1998, Volume: 42, Issue:2

    Topics: Adult; Aged; Azygos Vein; Blood Pressure; Drug Therapy, Combination; Female; Heart Rate; Hepatic Veins; Humans; Isosorbide Dinitrate; Liver Cirrhosis; Male; Middle Aged; Propranolol; Regional Blood Flow; Renal Circulation; Vasodilator Agents

1998
Clinical vs haemodynamic response to drugs in portal hypertension.
    Journal of hepatology, 1998, Volume: 28, Issue:6

    Topics: Adrenergic beta-Antagonists; Blood Pressure; Esophageal and Gastric Varices; Female; Follow-Up Studies; Hemodynamics; Humans; Hypertension, Portal; Isosorbide Dinitrate; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Octreotide; Propranolol; Recurrence; Sclerotherapy; Time Factors; Treatment Outcome; Vasodilator Agents

1998
Effect of chronic treatment with nadolol plus isosorbide mononitrate on liver blood flow and liver metabolic activity in cirrhosis.
    European journal of gastroenterology & hepatology, 1999, Volume: 11, Issue:11

    Topics: Adrenergic beta-Antagonists; Coloring Agents; Delayed-Action Preparations; Drug Therapy, Combination; Female; Hepatic Veins; Humans; Indocyanine Green; Isosorbide Dinitrate; Liver; Liver Circulation; Liver Cirrhosis; Male; Metabolic Clearance Rate; Middle Aged; Nadolol; Nitric Oxide Donors; Venous Pressure

1999
The hemodynamic response to medical treatment of portal hypertension as a predictor of clinical effectiveness in the primary prophylaxis of variceal bleeding in cirrhosis.
    Hepatology (Baltimore, Md.), 2000, Volume: 32, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Drug Therapy, Combination; Esophageal and Gastric Varices; Female; Hemodynamics; Hemorrhage; Humans; Hypertension, Portal; Isosorbide Dinitrate; Liver Cirrhosis; Male; Middle Aged; Nadolol; Prognosis; Vasodilator Agents

2000
Acute and chronic effects of isosorbide-5-mononitrate administration on effective renal plasma flow and the renin-aldosterone system in cirrhotic patients.
    Journal of gastroenterology and hepatology, 2000, Volume: 15, Issue:9

    Topics: Adult; Aged; Female; Humans; Isosorbide Dinitrate; Liver Cirrhosis; Male; Middle Aged; Renal Plasma Flow; Renin-Angiotensin System; Risk Factors; Vasodilator Agents

2000
[Isosorbide-5-mononitrate (mono mac) in the prevention of bleeding from esophageal varicose veins in patients with liver cirrhosis].
    Klinicheskaia meditsina, 2001, Volume: 79, Issue:2

    Topics: Adrenergic beta-Antagonists; Blood Pressure; Drug Therapy, Combination; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Isosorbide Dinitrate; Liver Cirrhosis; Treatment Outcome; Vasodilator Agents

2001
Enhancement of portal pressure reduction by the association of isosorbide-5-mononitrate to propranolol administration in patients with cirrhosis.
    Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:2

    Topics: Aged; Blood Pressure; Female; Hemodynamics; Humans; Hypertension, Portal; Isosorbide Dinitrate; Liver Circulation; Liver Cirrhosis; Male; Middle Aged; Propranolol; Time Factors; Vascular Resistance

1990
Effect and mechanism of action of isosorbide-5-mononitrate.
    Gut, 1988, Volume: 29, Issue:6

    Topics: Female; Hemodynamics; Humans; Hypertension, Portal; Isosorbide Dinitrate; Liver Cirrhosis; Male; Portal System

1988
Oral isosorbide-5-mononitrate: pharmacokinetics and clinical efficacy.
    International journal of clinical pharmacology, therapy, and toxicology, 1987, Volume: 25, Issue:3

    Topics: Administration, Oral; Coronary Disease; Drug Tolerance; Half-Life; Headache; Heart Failure; Humans; Isosorbide Dinitrate; Kidney Failure, Chronic; Kinetics; Liver Cirrhosis; Male

1987