isoproterenol has been researched along with Ventricular Dysfunction, Left in 88 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Ventricular Dysfunction, Left: A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study evaluated whether LCZ696 affects left ventricular hypertrophy, fibrosis, and hemodynamics in isoproterenol (ISO)-treated rats compared with valsartan alone." | 7.91 | Effect of LCZ696, a dual angiotensin receptor neprilysin inhibitor, on isoproterenol-induced cardiac hypertrophy, fibrosis, and hemodynamic change in rats. ( Akagi, S; Ito, H; Kondo, M; Miura, D; Miyoshi, T; Nakamura, K; Ohno, Y; Saito, Y; Yoshida, M, 2019) |
| " To assess the effects of phosphodiesterase type 3 and phosphodiesterase type 5 inhibitors on cardiac function and left ventricular myocardial fibrosis in catecholamine-induced myocardial injury, sildenafil and pimobendan were administered to male Wistar rats 24 hours after isoproterenol injection." | 7.91 | Contrasting Effects of Inhibition of Phosphodiesterase 3 and 5 on Cardiac Function and Interstitial Fibrosis in Rats With Isoproterenol-Induced Cardiac Dysfunction. ( Nakata, TM; Shimada, K; Suzuki, K; Tanaka, R; Uemura, A, 2019) |
| "Male Sprague Dawley rats were given isoproterenol 5 mg/kg once a day for 7 days to establish heart failure model by subcutaneous injection." | 7.85 | Protective effects of low-dose rosuvastatin on isoproterenol-induced chronic heart failure in rats by regulation of DDAH-ADMA-NO pathway. ( Ma, P; Wang, Y; Xiong, A; Xu, Q; Xu, Y; Zhou, R, 2017) |
| "Acute treatment with metformin has a protective effect in myocardial infarction by suppression of inflammatory responses due to activation of AMP-activated protein kinase (AMPK)." | 7.80 | Chronic treatment with metformin suppresses toll-like receptor 4 signaling and attenuates left ventricular dysfunction following myocardial infarction. ( Clanachan, AS; Garjani, A; Ghazi-Khansari, M; Maleki-Dizaji, N; Rameshrad, M; Soraya, H, 2014) |
| "The effect of atorvastatin on cardiac remodeling, function, and homodynamic parameters in isoproterenol-induced heart failure was evaluated in the present study." | 7.77 | Combined atorvastatin and coenzyme Q10 improve the left ventricular function in isoproterenol-induced heart failure in rat. ( Andalib, S; Biabani, S; Doustar, Y; Garjani, A; Maleki-Dizaji, N; Soraya, H, 2011) |
| "The aim of this study was to clarify the effects of renin-angiotensin system (RAS) blockade by captopril, an angiotensin converting enzyme inhibitor, and telmisartan, an angiotensin II type 1 receptor antagonist, on matrix metalloproteinase (MMP)-2 and MMP-9 expressions and development of left ventricular (LV) fibrosis induced by isoprenaline in rats." | 7.76 | Effects of captopril and telmisartan on matrix metalloproteinase-2 and -9 expressions and development of left ventricular fibrosis induced by isoprenaline in rats. ( Hara, Y; Hoshino, Y; Kosaka, N; Okada, M; Yamawaki, H, 2010) |
| "Furosemide activates the renin-angiotensin-aldosterone system in patients with congestive heart failure (CHF)." | 7.72 | Furosemide and the progression of left ventricular dysfunction in experimental heart failure. ( Haigney, MC; Hanlon, SU; McCurley, JM; Michalski, M; Wedam, EF; Wei, SK, 2004) |
| "We measured cardiac conformation, contractile performance and cytokines level in 8 age-matched normal adult rats (control group) and 8 rats with isoproterenol (ISO)-induced Heart failure (ISO group) and 8 rats with ISO-induced lesion but received EB treatment (EB group)." | 7.71 | Chronic treatment of enbrel in rats with isoproterenol-induced congestive heart failure limits left ventricular dysfunction and remodeling. ( Gan, R; Li, W; Sun, G, 2002) |
| "This study demonstrates that isoproterenol-induced myocardial necrosis resulted in progressive hemodynamic dysfunction of the left ventricle which most closely correlated with alterations in LV geometry." | 7.70 | Effect of left ventricular sphericity on the evolution of ventricular dysfunction in rats with diffuse isoproterenol-induced myocardial necrosis. ( Pfeffer, JM; Pfeffer, MA; Teerlink, JR, 1998) |
| "Isoflurane treatment was started at 0, 10, 30 (early treatment) or 120 (late treatment) minutes after isoprenaline injection." | 5.46 | Early treatment with isoflurane attenuates left ventricular dysfunction and improves survival in experimental Takotsubo. ( Ali, A; Alkhoury, J; Omerovic, E; Oras, J; Redfors, B; Ricksten, SE; Seeman-Lodding, H, 2017) |
| "Pre-treatment with ibuprofen (30, 60 and 90mg/kg p." | 5.43 | Inhibition of RhoA/Rho kinase by ibuprofen exerts cardioprotective effect on isoproterenol induced myocardial infarction in rats. ( Gandhi, T; Parikh, M; Patel, P; Shah, H, 2016) |
| " This study evaluated whether LCZ696 affects left ventricular hypertrophy, fibrosis, and hemodynamics in isoproterenol (ISO)-treated rats compared with valsartan alone." | 3.91 | Effect of LCZ696, a dual angiotensin receptor neprilysin inhibitor, on isoproterenol-induced cardiac hypertrophy, fibrosis, and hemodynamic change in rats. ( Akagi, S; Ito, H; Kondo, M; Miura, D; Miyoshi, T; Nakamura, K; Ohno, Y; Saito, Y; Yoshida, M, 2019) |
| " To assess the effects of phosphodiesterase type 3 and phosphodiesterase type 5 inhibitors on cardiac function and left ventricular myocardial fibrosis in catecholamine-induced myocardial injury, sildenafil and pimobendan were administered to male Wistar rats 24 hours after isoproterenol injection." | 3.91 | Contrasting Effects of Inhibition of Phosphodiesterase 3 and 5 on Cardiac Function and Interstitial Fibrosis in Rats With Isoproterenol-Induced Cardiac Dysfunction. ( Nakata, TM; Shimada, K; Suzuki, K; Tanaka, R; Uemura, A, 2019) |
| " The β-AR agonist isoproterenol (Iso) induced heart failure with high mortality in postpartum female, in non-pregnant female and in male CKO, but not in wild-type mice." | 3.85 | Low STAT3 expression sensitizes to toxic effects of β-adrenergic receptor stimulation in peripartum cardiomyopathy. ( Bauersachs, J; Bengel, FM; Bogeski, I; Erschow, S; Haghikia, A; Hagl, C; Hilfiker-Kleiner, D; Jauhiainen, M; Kappl, R; Knuuti, J; Kohlhaas, M; Maack, C; Müller, M; Nickel, AG; Pietzsch, S; Ricke-Hoch, M; Roivainen, A; Saar, JA; Saraste, A; Scherr, M; Sieve, I; Silvola, JM; Stapel, B; Thackeray, JT; Tudorache, I, 2017) |
| "Male Sprague Dawley rats were given isoproterenol 5 mg/kg once a day for 7 days to establish heart failure model by subcutaneous injection." | 3.85 | Protective effects of low-dose rosuvastatin on isoproterenol-induced chronic heart failure in rats by regulation of DDAH-ADMA-NO pathway. ( Ma, P; Wang, Y; Xiong, A; Xu, Q; Xu, Y; Zhou, R, 2017) |
| " Here, we determined whether North American ginseng can modulate the deleterious effects of the β-adrenoceptor agonist isoproterenol on cardiac hypertrophy and function using in vitro and in vivo approaches." | 3.83 | North American ginseng (Panax quinquefolius) suppresses β-adrenergic-dependent signalling, hypertrophy, and cardiac dysfunction. ( Gan, XT; Huang, CX; Karmazyn, M; Lui, EM; Rajapurohitam, V; Tang, X; Xue, J, 2016) |
| "Acute treatment with metformin has a protective effect in myocardial infarction by suppression of inflammatory responses due to activation of AMP-activated protein kinase (AMPK)." | 3.80 | Chronic treatment with metformin suppresses toll-like receptor 4 signaling and attenuates left ventricular dysfunction following myocardial infarction. ( Clanachan, AS; Garjani, A; Ghazi-Khansari, M; Maleki-Dizaji, N; Rameshrad, M; Soraya, H, 2014) |
| "Cardiac hypertrophy was induced in wild-type and IL-10 knockout mice by isoproterenol (ISO) infusion." | 3.78 | Interleukin-10 treatment attenuates pressure overload-induced hypertrophic remodeling and improves heart function via signal transducers and activators of transcription 3-dependent inhibition of nuclear factor-κB. ( Barefield, D; Ghosh, AK; Gupta, R; Hoxha, E; Kishore, R; Krishnamurthy, P; Lambers, E; Mackie, A; Qin, G; Ramirez, V; Sadayappan, S; Singh, N; Thal, M; Verma, SK, 2012) |
| "The effect of atorvastatin on cardiac remodeling, function, and homodynamic parameters in isoproterenol-induced heart failure was evaluated in the present study." | 3.77 | Combined atorvastatin and coenzyme Q10 improve the left ventricular function in isoproterenol-induced heart failure in rat. ( Andalib, S; Biabani, S; Doustar, Y; Garjani, A; Maleki-Dizaji, N; Soraya, H, 2011) |
| "The aim of this study was to clarify the effects of renin-angiotensin system (RAS) blockade by captopril, an angiotensin converting enzyme inhibitor, and telmisartan, an angiotensin II type 1 receptor antagonist, on matrix metalloproteinase (MMP)-2 and MMP-9 expressions and development of left ventricular (LV) fibrosis induced by isoprenaline in rats." | 3.76 | Effects of captopril and telmisartan on matrix metalloproteinase-2 and -9 expressions and development of left ventricular fibrosis induced by isoprenaline in rats. ( Hara, Y; Hoshino, Y; Kosaka, N; Okada, M; Yamawaki, H, 2010) |
| "The aim of the present study was performed to determine whether a novel histone deacetylase (HDAC) inhibitor, N-(2-aminophenyl)-4-{[benzyl(2-hydroxyethyl)amino]methyl} benzamide (K-183), prevents a reversible cardiac hypertrophy induced by isoproterenol and improves left ventricular (LV) dysfunction in rats." | 3.74 | Effects of a novel histone deacetylase inhibitor, N-(2-aminophenyl) benzamide, on a reversible hypertrophy induced by isoproterenol in in situ rat hearts. ( Kitagawa, Y; Nakajima-Takenaka, C; Shimizu, J; Takaki, M; Tamura, Y; Taniguchi, S; Uesato, S, 2007) |
| " We tested the hypothesis that this ACE gene polymorphism determines the extent of cardiac fibrosis induced by isoproterenol (Iso) in the rat." | 3.72 | Polymorphism in gene coding for ACE determines different development of myocardial fibrosis in rats. ( Carreño, JE; Díaz-Araya, G; Jalil, JE; Lavandero, S; Muñoz, D; Ocaranza, MP; Riveros, JP, 2004) |
| "Furosemide activates the renin-angiotensin-aldosterone system in patients with congestive heart failure (CHF)." | 3.72 | Furosemide and the progression of left ventricular dysfunction in experimental heart failure. ( Haigney, MC; Hanlon, SU; McCurley, JM; Michalski, M; Wedam, EF; Wei, SK, 2004) |
| "We measured cardiac conformation, contractile performance and cytokines level in 8 age-matched normal adult rats (control group) and 8 rats with isoproterenol (ISO)-induced Heart failure (ISO group) and 8 rats with ISO-induced lesion but received EB treatment (EB group)." | 3.71 | Chronic treatment of enbrel in rats with isoproterenol-induced congestive heart failure limits left ventricular dysfunction and remodeling. ( Gan, R; Li, W; Sun, G, 2002) |
| "We administered oral metoprolol or no therapy to rats for 12 weeks after large myocardial infarction and subsequently examined left ventricular (LV) remodeling; myocardial tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta, and IL-6 expression; and NO." | 3.70 | beta-adrenergic blockade in developing heart failure: effects on myocardial inflammatory cytokines, nitric oxide, and remodeling. ( Chandrasekar, B; Freeman, GL; Murray, DR; Prabhu, SD, 2000) |
| "The equivalent of the clinically used low (= antiplatelet)-dose aspirin, inhibited collagen deposition in the non-infarcted myocardium in rats with myocardial infarction." | 3.70 | Low-dose aspirin improves in vivo hemodynamics in conscious, chronically infarcted rats. ( Kalkman, EA; Saxena, PR; Schoemaker, RG, 1998) |
| "This study demonstrates that isoproterenol-induced myocardial necrosis resulted in progressive hemodynamic dysfunction of the left ventricle which most closely correlated with alterations in LV geometry." | 3.70 | Effect of left ventricular sphericity on the evolution of ventricular dysfunction in rats with diffuse isoproterenol-induced myocardial necrosis. ( Pfeffer, JM; Pfeffer, MA; Teerlink, JR, 1998) |
| "However, it failed to affect left ventricular hypertrophy and even aggravated the impaired positive and negative lusitropic effects elicited by isoprenaline and carbachol, respectively." | 1.62 | Chronic cannabidiol treatment reduces the carbachol-induced coronary constriction and left ventricular cardiomyocyte width of the isolated hypertensive rat heart. ( Gajo, B; Harasim-Symbor, E; Kasacka, I; Malinowska, B; Pędzińska-Betiuk, A; Schlicker, E; Toczek, M; Weresa, J, 2021) |
| "Hypertension is a major cause of left ventricular (LV) diastolic dysfunction." | 1.48 | Limited Impact of β-Adrenergic Receptor Activation on Left Ventricular Diastolic Function in Rat Models of Hypertensive Heart Disease. ( Bamaiyi, AJ; Mojiminiyi, FB; Norman, G; Norton, GR; Peterson, V; Woodiwiss, AJ, 2018) |
| "Isoflurane treatment was started at 0, 10, 30 (early treatment) or 120 (late treatment) minutes after isoprenaline injection." | 1.46 | Early treatment with isoflurane attenuates left ventricular dysfunction and improves survival in experimental Takotsubo. ( Ali, A; Alkhoury, J; Omerovic, E; Oras, J; Redfors, B; Ricksten, SE; Seeman-Lodding, H, 2017) |
| "Pre-treatment with ibuprofen (30, 60 and 90mg/kg p." | 1.43 | Inhibition of RhoA/Rho kinase by ibuprofen exerts cardioprotective effect on isoproterenol induced myocardial infarction in rats. ( Gandhi, T; Parikh, M; Patel, P; Shah, H, 2016) |
| "While Huntington's disease (HD) is classified as a neurological disorder, HD patients exhibit a high incidence of cardiovascular events leading to heart failure and death." | 1.43 | Cardiac Dysfunction in the BACHD Mouse Model of Huntington's Disease. ( Colwell, CS; Coppola, G; Fishbein, MC; Gao, F; Ghiani, CA; Jordan, MC; Park, S; Roos, KP; Schroeder, AM; Wang, HB, 2016) |
| "All mice were 10 weeks of age." | 1.40 | Gestational hypertension and the developmental origins of cardiac hypertrophy and diastolic dysfunction. ( Armstrong, DW; Johri, AM; Matangi, MF; Meens, JA; Pang, SC; Tse, MY; Ventura, NM; Wong, PG, 2014) |
| "Curcumin was administered orally for 15 days to all the treated groups." | 1.36 | Curcumin protects rat myocardium against isoproterenol-induced ischemic injury: attenuation of ventricular dysfunction through increased expression of Hsp27 along with strengthening antioxidant defense system. ( Arya, DS; Golechha, M; Kumari, S; Sachdeva, J; Tanwar, V, 2010) |
| "The transition from compensated left ventricular hypertrophy (LVH) to heart failure is associated with alterations in the myocardial interstitium." | 1.31 | Reduction in myocardial collagen cross-linking parallels left ventricular dilatation in rat models of systolic chamber dysfunction. ( Chung, ES; Lancaster, EJ; Mela, T; Meyer, TE; Norton, GR; Sprott, S; Tsotetsi, OJ; Woodiwiss, AJ, 2001) |
| "Ventricular arrhythmias and contractile dysfunction are the main causes of death in human heart failure (HF)." | 1.31 | Arrhythmogenesis and contractile dysfunction in heart failure: Roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness. ( Bers, DM; Li, L; Pogwizd, SM; Schlotthauer, K; Yuan, W, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (11.36) | 18.2507 |
| 2000's | 36 (40.91) | 29.6817 |
| 2010's | 37 (42.05) | 24.3611 |
| 2020's | 5 (5.68) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, HB | 2 |
| Yang, J | 3 |
| Shuai, W | 1 |
| Liu, LB | 1 |
| Xu, M | 1 |
| Tang, QZ | 1 |
| Sun, TL | 1 |
| Li, WQ | 1 |
| Tong, XL | 1 |
| Liu, XY | 1 |
| Zhou, WH | 1 |
| Pędzińska-Betiuk, A | 1 |
| Weresa, J | 1 |
| Schlicker, E | 1 |
| Harasim-Symbor, E | 1 |
| Toczek, M | 1 |
| Kasacka, I | 1 |
| Gajo, B | 1 |
| Malinowska, B | 1 |
| Coquerel, D | 1 |
| Delile, E | 1 |
| Dumont, L | 1 |
| Chagnon, F | 1 |
| Murza, A | 1 |
| Sainsily, X | 1 |
| Salvail, D | 1 |
| Sarret, P | 1 |
| Marsault, E | 1 |
| Auger-Messier, M | 1 |
| Lesur, O | 1 |
| Mashali, MA | 1 |
| Saad, NS | 1 |
| Canan, BD | 1 |
| Elnakish, MT | 1 |
| Milani-Nejad, N | 1 |
| Chung, JH | 1 |
| Schultz, EJ | 1 |
| Kiduko, SA | 1 |
| Huang, AW | 1 |
| Hare, AN | 1 |
| Peczkowski, KK | 1 |
| Fazlollahi, F | 1 |
| Martin, BL | 1 |
| Murray, JD | 1 |
| Campbell, CM | 1 |
| Kilic, A | 1 |
| Whitson, BA | 1 |
| Mokadam, NA | 1 |
| Mohler, PJ | 1 |
| Janssen, PML | 1 |
| Myers, VD | 1 |
| Tomar, D | 1 |
| Madesh, M | 1 |
| Wang, J | 1 |
| Song, J | 1 |
| Zhang, XQ | 1 |
| Gupta, MK | 1 |
| Tahrir, FG | 1 |
| Gordon, J | 1 |
| McClung, JM | 1 |
| Kontos, CD | 1 |
| Khalili, K | 1 |
| Cheung, JY | 1 |
| Feldman, AM | 1 |
| Miyoshi, T | 1 |
| Nakamura, K | 1 |
| Miura, D | 1 |
| Yoshida, M | 1 |
| Saito, Y | 1 |
| Akagi, S | 1 |
| Ohno, Y | 1 |
| Kondo, M | 1 |
| Ito, H | 1 |
| Bamaiyi, AJ | 1 |
| Norton, GR | 7 |
| Peterson, V | 1 |
| Norman, G | 1 |
| Mojiminiyi, FB | 1 |
| Woodiwiss, AJ | 7 |
| Nakata, TM | 1 |
| Suzuki, K | 1 |
| Uemura, A | 1 |
| Shimada, K | 1 |
| Tanaka, R | 1 |
| Beyhoff, N | 1 |
| Lohr, D | 1 |
| Foryst-Ludwig, A | 1 |
| Klopfleisch, R | 1 |
| Brix, S | 1 |
| Grune, J | 1 |
| Thiele, A | 1 |
| Erfinanda, L | 1 |
| Tabuchi, A | 1 |
| Kuebler, WM | 1 |
| Pieske, B | 1 |
| Schreiber, LM | 1 |
| Kintscher, U | 1 |
| Raymond, AR | 1 |
| Hodson, B | 1 |
| Brooksbank, RL | 1 |
| Armstrong, DW | 1 |
| Tse, MY | 1 |
| Wong, PG | 1 |
| Ventura, NM | 1 |
| Meens, JA | 1 |
| Johri, AM | 1 |
| Matangi, MF | 1 |
| Pang, SC | 1 |
| Soraya, H | 2 |
| Clanachan, AS | 1 |
| Rameshrad, M | 1 |
| Maleki-Dizaji, N | 2 |
| Ghazi-Khansari, M | 1 |
| Garjani, A | 3 |
| Toldo, S | 1 |
| Mezzaroma, E | 1 |
| Bressi, E | 1 |
| Marchetti, C | 1 |
| Carbone, S | 1 |
| Sonnino, C | 1 |
| Van Tassell, BW | 1 |
| Abbate, A | 1 |
| Fernandes, AA | 2 |
| Ribeiro, RF | 2 |
| de Moura, VG | 1 |
| Siman, FD | 1 |
| Dias, FM | 2 |
| Zoghaib, J | 1 |
| Vassallo, PF | 1 |
| Vassallo, DV | 3 |
| Stefanon, I | 3 |
| Tsai, WC | 1 |
| Lu, YY | 1 |
| Chen, YC | 1 |
| Chang, CJ | 1 |
| Kao, YH | 1 |
| Lin, YK | 1 |
| Chen, YH | 1 |
| Chen, SA | 1 |
| Yang, LY | 1 |
| Chen, YJ | 1 |
| Vergaro, G | 1 |
| Prud'homme, M | 1 |
| Fazal, L | 1 |
| Merval, R | 1 |
| Passino, C | 1 |
| Emdin, M | 1 |
| Samuel, JL | 2 |
| Cohen Solal, A | 1 |
| Delcayre, C | 1 |
| Schroeder, AM | 1 |
| Park, S | 1 |
| Jordan, MC | 1 |
| Gao, F | 1 |
| Coppola, G | 1 |
| Fishbein, MC | 1 |
| Roos, KP | 1 |
| Ghiani, CA | 1 |
| Colwell, CS | 1 |
| Kim, TH | 1 |
| Lee, JS | 1 |
| Park, J | 1 |
| Park, JK | 1 |
| Uhm, JS | 1 |
| Joung, B | 1 |
| Lee, MH | 1 |
| Pak, HN | 1 |
| Patel, P | 1 |
| Parikh, M | 1 |
| Shah, H | 1 |
| Gandhi, T | 1 |
| Michel, FS | 1 |
| Magubane, M | 1 |
| Mokotedi, L | 1 |
| Tang, X | 1 |
| Gan, XT | 1 |
| Rajapurohitam, V | 1 |
| Huang, CX | 1 |
| Xue, J | 1 |
| Lui, EM | 1 |
| Karmazyn, M | 1 |
| Zhou, R | 1 |
| Ma, P | 1 |
| Xiong, A | 1 |
| Xu, Y | 1 |
| Wang, Y | 2 |
| Xu, Q | 1 |
| Oras, J | 1 |
| Redfors, B | 2 |
| Ali, A | 1 |
| Alkhoury, J | 1 |
| Seeman-Lodding, H | 1 |
| Omerovic, E | 3 |
| Ricksten, SE | 1 |
| Stapel, B | 1 |
| Kohlhaas, M | 1 |
| Ricke-Hoch, M | 1 |
| Haghikia, A | 1 |
| Erschow, S | 1 |
| Knuuti, J | 1 |
| Silvola, JM | 1 |
| Roivainen, A | 1 |
| Saraste, A | 1 |
| Nickel, AG | 1 |
| Saar, JA | 1 |
| Sieve, I | 1 |
| Pietzsch, S | 1 |
| Müller, M | 1 |
| Bogeski, I | 1 |
| Kappl, R | 1 |
| Jauhiainen, M | 1 |
| Thackeray, JT | 1 |
| Scherr, M | 1 |
| Bengel, FM | 1 |
| Hagl, C | 1 |
| Tudorache, I | 1 |
| Bauersachs, J | 1 |
| Maack, C | 1 |
| Hilfiker-Kleiner, D | 1 |
| Maier, T | 1 |
| Schreckenberg, R | 1 |
| Schlüter, KD | 1 |
| Fang, Q | 2 |
| Kan, H | 2 |
| Lewis, W | 1 |
| Chen, F | 1 |
| Sharma, P | 1 |
| Finkel, MS | 2 |
| Schumacher, A | 1 |
| Khojeini, E | 1 |
| Larson, D | 1 |
| Yoo, B | 1 |
| Lemaire, A | 1 |
| Mangmool, S | 1 |
| Wolf, MJ | 1 |
| Curcio, A | 1 |
| Mao, L | 1 |
| Rockman, HA | 1 |
| Wong, J | 1 |
| Chang, C | 1 |
| Agrawal, R | 1 |
| Walton, GB | 1 |
| Chen, C | 1 |
| Murthy, A | 1 |
| Patterson, AJ | 1 |
| Gotic, I | 1 |
| Leschnik, M | 1 |
| Kolm, U | 1 |
| Markovic, M | 1 |
| Haubner, BJ | 1 |
| Biadasiewicz, K | 1 |
| Metzler, B | 1 |
| Stewart, CL | 1 |
| Foisner, R | 1 |
| Tanwar, V | 1 |
| Sachdeva, J | 1 |
| Golechha, M | 2 |
| Kumari, S | 2 |
| Arya, DS | 2 |
| Xu, L | 1 |
| Lai, D | 1 |
| Cheng, J | 1 |
| Lim, HJ | 1 |
| Keskanokwong, T | 1 |
| Backs, J | 1 |
| Olson, EN | 2 |
| Guellich, A | 1 |
| Gao, S | 1 |
| Hong, C | 1 |
| Yan, L | 1 |
| Wagner, TE | 1 |
| Dhar, SK | 1 |
| Ghaleh, B | 1 |
| Hittinger, L | 1 |
| Iwatsubo, K | 1 |
| Ishikawa, Y | 1 |
| Vatner, SF | 1 |
| Vatner, DE | 1 |
| Okada, M | 1 |
| Kosaka, N | 1 |
| Hoshino, Y | 1 |
| Yamawaki, H | 1 |
| Hara, Y | 1 |
| Birkenfeld, AL | 1 |
| Adams, F | 1 |
| Schroeder, C | 1 |
| Engeli, S | 1 |
| Jordan, J | 1 |
| Jimenez, SK | 1 |
| Jassal, DS | 1 |
| Kardami, E | 1 |
| Cattini, PA | 1 |
| Andalib, S | 1 |
| Biabani, S | 1 |
| Doustar, Y | 1 |
| Vitiello, D | 1 |
| Boissière, J | 1 |
| Doucende, G | 1 |
| Gayrard, S | 1 |
| Polge, A | 1 |
| Faure, P | 1 |
| Goux, A | 1 |
| Tanguy, S | 1 |
| Obert, P | 1 |
| Reboul, C | 1 |
| Nottin, S | 1 |
| Parveen, A | 1 |
| Babbar, R | 1 |
| Agarwal, S | 1 |
| Kotwani, A | 1 |
| Fahim, M | 1 |
| Ojha, S | 1 |
| Täng, MS | 1 |
| Shao, Y | 1 |
| Gai, Y | 1 |
| Ma, Z | 1 |
| Yu, X | 1 |
| Qu, S | 1 |
| Sui, D | 1 |
| Verma, SK | 1 |
| Krishnamurthy, P | 1 |
| Barefield, D | 1 |
| Singh, N | 1 |
| Gupta, R | 1 |
| Lambers, E | 1 |
| Thal, M | 1 |
| Mackie, A | 1 |
| Hoxha, E | 1 |
| Ramirez, V | 1 |
| Qin, G | 1 |
| Sadayappan, S | 1 |
| Ghosh, AK | 1 |
| Kishore, R | 1 |
| Pavan, BM | 1 |
| Potratz, FF | 1 |
| Fiorim, J | 1 |
| Simoes, MR | 1 |
| Lima, FL | 1 |
| Nichtova, Z | 1 |
| Novotova, M | 1 |
| Kralova, E | 1 |
| Stankovicova, T | 1 |
| Li, W | 1 |
| Gan, R | 1 |
| Sun, G | 1 |
| Steine, K | 1 |
| Stugaard, M | 1 |
| Smiseth, O | 1 |
| Min, JY | 1 |
| Sullivan, MF | 1 |
| Yan, X | 1 |
| Feng, X | 1 |
| Chu, V | 1 |
| Wang, JF | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT02138695] | 3,100 participants (Anticipated) | Observational | 2014-05-31 | Recruiting | |||
| Metabolic Signalling in Muscle- and Adipose Tissue Following Insulin Withdrawal and Growth Hormone Injection in Type I Diabetes Mellitus, a Clinical Experimental Study.[NCT02077348] | 9 participants (Actual) | Interventional | 2014-05-31 | Completed | |||
| The Role of ATGL and G0/G1 Switch Gene Complex in Lipopolysaccaride (LPS) Induced Ketosis - a Controlled, Randomised, Clinical Experimental Study[NCT02157155] | 9 participants (Actual) | Interventional | 2014-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for isoproterenol and Ventricular Dysfunction, Left
| Article | Year |
|---|---|
Morphological and functional characteristics of models of experimental myocardial injury induced by isoproterenol.
Topics: Animals; Disease Models, Animal; Heart Conduction System; Humans; Isoproterenol; Myocardial Contract | 2012 |
Cellular and molecular therapeutic targets for treatment of contractile dysfunction after cardioplegic arrest.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cardioplegic Solutions; Cells, Cultured; Heart Arrest, I | 1999 |
Adrenergic overload and apoptosis in heart failure: implications for therapy.
Topics: Adrenergic beta-Agonists; Animals; Animals, Newborn; Apoptosis; Gene Expression Regulation; Heart Fa | 2000 |
1 trial available for isoproterenol and Ventricular Dysfunction, Left
| Article | Year |
|---|---|
Blunted rate-dependent left atrial pressure response during isoproterenol infusion in atrial fibrillation patients with impaired left ventricular diastolic function: a comparison to pacing.
Topics: Atrial Fibrillation; Atrial Pressure; Cardiac Pacing, Artificial; Cardiotonic Agents; Catheter Ablat | 2015 |
84 other studies available for isoproterenol and Ventricular Dysfunction, Left
| Article | Year |
|---|---|
Deletion of Microfibrillar-Associated Protein 4 Attenuates Left Ventricular Remodeling and Dysfunction in Heart Failure.
Topics: Adrenergic beta-Agonists; Animals; Aorta; Biomechanical Phenomena; Cardiomegaly; Carrier Proteins; C | 2020 |
Xanthohumol attenuates isoprenaline-induced cardiac hypertrophy and fibrosis through regulating PTEN/AKT/mTOR pathway.
Topics: Animals; Disease Models, Animal; Fibrosis; Flavonoids; Hypertrophy, Left Ventricular; Isoproterenol; | 2021 |
Chronic cannabidiol treatment reduces the carbachol-induced coronary constriction and left ventricular cardiomyocyte width of the isolated hypertensive rat heart.
Topics: Adrenergic beta-Agonists; Animals; Antihypertensive Agents; Cannabidiol; Carbachol; Cell Size; Coron | 2021 |
Gαi-biased apelin analog protects against isoproterenol-induced myocardial dysfunction in rats.
Topics: Adenylyl Cyclases; Animals; Apelin; Apelin Receptors; Calcium-Binding Proteins; Cells, Cultured; Cyc | 2021 |
Impact of etiology on force and kinetics of left ventricular end-stage failing human myocardium.
Topics: Biomarkers; Data Analysis; Disease Susceptibility; Female; Heart Failure; Heart Failure, Diastolic; | 2021 |
Haplo-insufficiency of Bcl2-associated athanogene 3 in mice results in progressive left ventricular dysfunction, β-adrenergic insensitivity, and increased apoptosis.
Topics: Adaptor Proteins, Signal Transducing; Adrenergic Agents; Animals; Apoptosis; Apoptosis Regulatory Pr | 2018 |
Effect of LCZ696, a dual angiotensin receptor neprilysin inhibitor, on isoproterenol-induced cardiac hypertrophy, fibrosis, and hemodynamic change in rats.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Disease Models, Anima | 2019 |
Limited Impact of β-Adrenergic Receptor Activation on Left Ventricular Diastolic Function in Rat Models of Hypertensive Heart Disease.
Topics: Adrenergic beta-Agonists; Animals; Diastole; Disease Models, Animal; Echocardiography, Doppler, Puls | 2018 |
Contrasting Effects of Inhibition of Phosphodiesterase 3 and 5 on Cardiac Function and Interstitial Fibrosis in Rats With Isoproterenol-Induced Cardiac Dysfunction.
Topics: Animals; Arrhythmias, Cardiac; Collagen Type I; Collagen Type III; Disease Models, Animal; Fibrosis; | 2019 |
Characterization of Myocardial Microstructure and Function in an Experimental Model of Isolated Subendocardial Damage.
Topics: Animals; Biopsy, Needle; Disease Models, Animal; Echocardiography; Endocardium; Fibrosis; Germany; H | 2019 |
Telomere length and adrenergic-induced left ventricular dilatation and systolic chamber dysfunction in rats.
Topics: Adrenergic beta-Agonists; Animals; Cardiomyopathy, Dilated; Heart Ventricles; Isoproterenol; Male; R | 2013 |
Gestational hypertension and the developmental origins of cardiac hypertrophy and diastolic dysfunction.
Topics: Adrenergic beta-Agonists; Animals; Atrial Natriuretic Factor; Cardiomegaly; Female; Fibrosis; GATA T | 2014 |
Chronic treatment with metformin suppresses toll-like receptor 4 signaling and attenuates left ventricular dysfunction following myocardial infarction.
Topics: AMP-Activated Protein Kinases; Animals; Hemodynamics; Interleukin-6; Isoproterenol; Male; Metformin; | 2014 |
Interleukin-1β blockade improves left ventricular systolic/diastolic function and restores contractility reserve in severe ischemic cardiomyopathy in the mouse.
Topics: Animals; Antibodies, Monoclonal; Disease Models, Animal; Echocardiography; Interleukin-1beta; Isopro | 2014 |
SERCA-2a is involved in the right ventricular function following myocardial infarction in rats.
Topics: Animals; Disease Models, Animal; Gene Expression Regulation; Heart Failure; Isometric Contraction; I | 2015 |
Ablation of androgen receptor gene triggers right ventricular outflow tract ventricular tachycardia.
Topics: Action Potentials; Adenosine; Animals; Caffeine; Calcium; Flecainide; Gene Knockdown Techniques; Gen | 2015 |
Inhibition of Galectin-3 Pathway Prevents Isoproterenol-Induced Left Ventricular Dysfunction and Fibrosis in Mice.
Topics: Animals; Disease Models, Animal; Echocardiography; Fibrosis; Galectin 3; Gene Expression Regulation; | 2016 |
Cardiac Dysfunction in the BACHD Mouse Model of Huntington's Disease.
Topics: Adrenergic beta-Agonists; Aging; Animals; Apoptosis; Cardiomegaly; Disease Models, Animal; Fibrosis; | 2016 |
Inhibition of RhoA/Rho kinase by ibuprofen exerts cardioprotective effect on isoproterenol induced myocardial infarction in rats.
Topics: Animals; Antioxidants; Cardiotonic Agents; Electrocardiography; Gene Expression Regulation, Enzymolo | 2016 |
Sex-Specific Effects of Adrenergic-Induced Left Ventricular Remodeling in Spontaneously Hypertensive Rats.
Topics: Adrenergic Agents; Animals; Cells, Cultured; Disease Models, Animal; Female; Isoproterenol; Male; My | 2017 |
North American ginseng (Panax quinquefolius) suppresses β-adrenergic-dependent signalling, hypertrophy, and cardiac dysfunction.
Topics: Adrenergic beta-Agonists; Animals; Cardiomegaly; Dose-Response Relationship, Drug; Isoproterenol; Ma | 2016 |
Protective effects of low-dose rosuvastatin on isoproterenol-induced chronic heart failure in rats by regulation of DDAH-ADMA-NO pathway.
Topics: Amidohydrolases; Animals; Biomarkers; Cardiotonic Agents; Disease Models, Animal; Fibrosis; Heart Fa | 2017 |
Early treatment with isoflurane attenuates left ventricular dysfunction and improves survival in experimental Takotsubo.
Topics: Adrenergic beta-Agonists; Anesthetics, Inhalation; Animals; Cardiac Output; Echocardiography; Isoflu | 2017 |
Low STAT3 expression sensitizes to toxic effects of β-adrenergic receptor stimulation in peripartum cardiomyopathy.
Topics: Adrenergic beta-1 Receptor Agonists; Adult; Animals; Blood Glucose; Cardiomyopathies; Dobutamine; Fe | 2017 |
Effect of preischemic beta-adrenoceptor stimulation on postischemic contractile dysfunction.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Female; Hemodynamics; Hyperte | 2009 |
Dilated cardiomyopathy in transgenic mice expressing HIV Tat.
Topics: Adrenergic beta-Agonists; Age Factors; Animals; Blood Pressure; Bradycardia; Cardiomyopathy, Dilated | 2009 |
ECHO parameters of diastolic dysfunction.
Topics: Animals; Cardiotonic Agents; Diastole; Echocardiography, Transesophageal; Female; Heart; Isoproteren | 2008 |
Beta1-adrenergic receptors stimulate cardiac contractility and CaMKII activation in vivo and enhance cardiac dysfunction following myocardial infarction.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-Agonists; Animals; Apoptosis; Calcium-Calmoduli | 2009 |
Gene expression profiling: classification of mice with left ventricle systolic dysfunction using microarray analysis.
Topics: Animals; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Isoprotereno | 2010 |
Lamina-associated polypeptide 2alpha loss impairs heart function and stress response in mice.
Topics: Adrenergic beta-Agonists; Animals; Blotting, Western; DNA-Binding Proteins; Dystrophin; Echocardiogr | 2010 |
Curcumin protects rat myocardium against isoproterenol-induced ischemic injury: attenuation of ventricular dysfunction through increased expression of Hsp27 along with strengthening antioxidant defense system.
Topics: Animals; Antioxidants; Blood Pressure; Catalase; Creatine Kinase, MB Form; Curcumin; Glutathione; He | 2010 |
Alterations of L-type calcium current and cardiac function in CaMKII{delta} knockout mice.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blotting, Western; Body Weight; Calcium; Calcium Ch | 2010 |
Effects of cardiac overexpression of type 6 adenylyl cyclase affects on the response to chronic pressure overload.
Topics: Adenylyl Cyclases; Analysis of Variance; Animals; Apoptosis; Colforsin; Echocardiography; Heart; Hea | 2010 |
Effects of captopril and telmisartan on matrix metalloproteinase-2 and -9 expressions and development of left ventricular fibrosis induced by isoprenaline in rats.
Topics: Animals; Benzimidazoles; Benzoates; Captopril; Drug Therapy, Combination; Fibrosis; Gene Expression | 2010 |
Metabolic actions could confound advantageous effects of combined angiotensin II receptor and neprilysin inhibition.
Topics: Adipocytes; Adrenergic beta-Agonists; Aminobutyrates; Angiotensin Receptor Antagonists; Atrial Natri | 2011 |
A single bout of exercise promotes sustained left ventricular function improvement after isoproterenol-induced injury in mice.
Topics: Animals; Echocardiography, Doppler; Female; Heart; Heart Injuries; Isoproterenol; Male; Mice; Mice, | 2011 |
Combined atorvastatin and coenzyme Q10 improve the left ventricular function in isoproterenol-induced heart failure in rat.
Topics: Animals; Atorvastatin; Body Weight; Drug Interactions; Heart Failure; Hemodynamics; Heptanoic Acids; | 2011 |
β-Adrenergic receptors desensitization is not involved in exercise-induced cardiac fatigue: NADPH oxidase-induced oxidative stress as a new trigger.
Topics: Acetophenones; Animals; Heart Failure; Heart Ventricles; Isoproterenol; Lipid Peroxidation; Male; My | 2011 |
Terminalia arjuna enhances baroreflex sensitivity and myocardial function in isoproterenol-induced chronic heart failure rats.
Topics: Animals; Antioxidants; Baroreflex; Chronic Disease; Cytokines; Disease Models, Animal; Fatty Acids, | 2012 |
Protective effect of Emblica officinalis (amla) on isoproterenol-induced cardiotoxicity in rats.
Topics: Analysis of Variance; Animals; Antioxidants; Biomarkers; Blood Pressure; Cardiotonic Agents; Cardiot | 2012 |
Velocity vector imaging fails to quantify regional myocardial dysfunction in a mouse model of isoprenaline-induced cardiotoxicity.
Topics: Algorithms; Animals; Disease Models, Animal; Echocardiography; Elasticity Imaging Techniques; Humans | 2012 |
Effect of ginsenoside Rh1 on myocardial injury and heart function in isoproterenol-induced cardiotoxicity in rats.
Topics: Animals; Blood Pressure; Cardiotonic Agents; Creatine Kinase; Disease Models, Animal; Ginsenosides; | 2012 |
Interleukin-10 treatment attenuates pressure overload-induced hypertrophic remodeling and improves heart function via signal transducers and activators of transcription 3-dependent inhibition of nuclear factor-κB.
Topics: Animals; Cardiomegaly; Disease Models, Animal; Disease Susceptibility; Fibrosis; Interleukin-10; Iso | 2012 |
Myocardial contractile dysfunction induced by ovariectomy requires AT1 receptor activation in female rats.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Estrogens; Female; In Vitro Techniques; Isoproterenol; M | 2012 |
Chronic treatment of enbrel in rats with isoproterenol-induced congestive heart failure limits left ventricular dysfunction and remodeling.
Topics: Animals; Body Weight; Echocardiography; Etanercept; Heart Failure; Immunoglobulin G; Interleukin-1; | 2002 |
Mechanisms of diastolic intraventricular regional pressure differences and flow in the inflow and outflow tracts.
Topics: Animals; Coronary Disease; Diastole; Dogs; Echocardiography, Doppler; Female; Isoproterenol; Male; V | 2002 |
Overexpression of Na+/Ca2+ exchanger gene attenuates postinfarction myocardial dysfunction.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Disease Models, Animal; Disease Progression; Electrocard | 2002 |
Polymorphism in gene coding for ACE determines different development of myocardial fibrosis in rats.
Topics: Animals; Cardiomegaly; Cell Division; Female; Fibrosis; Genotype; Heart; Isoproterenol; Male; Matrix | 2004 |
Diabetes increases formation of advanced glycation end products on Sarco(endo)plasmic reticulum Ca2+-ATPase.
Topics: Animals; Calcium-Transporting ATPases; Diabetes Mellitus, Experimental; Glycation End Products, Adva | 2004 |
Furosemide and the progression of left ventricular dysfunction in experimental heart failure.
Topics: Adrenergic beta-Agonists; Aldosterone; Animals; Biomarkers; Disease Models, Animal; Disease Progress | 2004 |
Role of myocardial neuronal nitric oxide synthase-derived nitric oxide in beta-adrenergic hyporesponsiveness after myocardial infarction-induced heart failure in rat.
Topics: Adrenergic beta-Agonists; Animals; Autocrine Communication; Caveolin 3; Caveolins; Dobutamine; Enzym | 2004 |
Effect of isoproterenol on the cardiac troponin I degradation and release during early TNFalpha-induced ventricular dysfunction in isolated rabbit heart.
Topics: Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; France; Heart Injuries; Hum | 2004 |
Impact of beta-myosin heavy chain expression on cardiac function during stress.
Topics: Animals; Body Weight; Cardiac Output, Low; Cardiomegaly; Cardiotonic Agents; Chronic Disease; Dobuta | 2004 |
Selective cerebral overexpression of growth hormone alters cardiac function, morphology, energy metabolism and catecholamines in transgenic mice.
Topics: Animals; Brain; Catecholamines; Cattle; Dopamine; Echocardiography; Energy Metabolism; Female; Glial | 2005 |
Aldosterone receptor blockade prevents the transition to cardiac pump dysfunction induced by beta-adrenoreceptor activation.
Topics: Adrenergic beta-Agonists; Animals; Collagen; Echocardiography; Heart; Hypertension; Hypertrophy, Lef | 2005 |
Cardiac transgenic matrix metalloproteinase-2 expression directly induces impaired contractility.
Topics: Actin Cytoskeleton; Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Calcium; Colforsin; Ele | 2006 |
Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase.
Topics: Adipocytes; Adipose Tissue; Adipose Tissue, Brown; Animals; Blood Glucose; Carboxylic Ester Hydrolas | 2006 |
Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase.
Topics: Adipocytes; Adipose Tissue; Adipose Tissue, Brown; Animals; Blood Glucose; Carboxylic Ester Hydrolas | 2006 |
Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase.
Topics: Adipocytes; Adipose Tissue; Adipose Tissue, Brown; Animals; Blood Glucose; Carboxylic Ester Hydrolas | 2006 |
Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase.
Topics: Adipocytes; Adipose Tissue; Adipose Tissue, Brown; Animals; Blood Glucose; Carboxylic Ester Hydrolas | 2006 |
Enhanced isoproterenol-induced cardiac hypertrophy in transgenic rats with low brain angiotensinogen.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Angiotensinogen; Animals; Animals, Geneticall | 2006 |
Death, cardiac dysfunction, and arrhythmias are increased by calmodulin kinase II in calcineurin cardiomyopathy.
Topics: Amino Acid Sequence; Animals; Animals, Newborn; Apoptosis; Arrhythmias, Cardiac; Benzylamines; Calci | 2006 |
Magnesium attenuates isoproterenol-induced acute cardiac dysfunction and beta-adrenergic desensitization.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Dogs; Female; Heart Diseases; Isoproterenol; Magnesium; Ma | 2007 |
Enhanced beta-adrenergic response in rat papillary muscle by inhibition of inducible nitric oxide synthase after myocardial infarction.
Topics: Adrenergic beta-Agonists; Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Isoprotereno | 2007 |
Effects of a novel histone deacetylase inhibitor, N-(2-aminophenyl) benzamide, on a reversible hypertrophy induced by isoproterenol in in situ rat hearts.
Topics: Analysis of Variance; Animals; Benzamides; Cardiac Catheterization; Cardiac Output; Cardiomegaly; Co | 2007 |
Temporal changes in myocardial adrenergic regulation with the progression to pump dysfunction after chronic beta-adrenoreceptor activation in rats.
Topics: Adrenergic beta-Agonists; Animals; Disease Models, Animal; Heart Ventricles; Isoproterenol; Male; My | 2007 |
Susceptibility to systolic dysfunction in the myocardium from chronically infarcted spontaneously hypertensive rats.
Topics: Animals; Apoptosis; Cardiotonic Agents; Coronary Vessels; Disease Models, Animal; Hypertension; Isop | 2008 |
Inducible nitric oxide synthase attenuates adrenergic signaling in alcohol fed rats.
Topics: Administration, Oral; Adrenergic beta-Agonists; Animals; Blotting, Western; Caloric Restriction; Ele | 2007 |
Ethanol extract from Epimedium brevicornum attenuates left ventricular dysfunction and cardiac remodeling through down-regulating matrix metalloproteinase-2 and -9 activity and myocardial apoptosis in rats with congestive heart failure.
Topics: Animals; Apoptosis; Chromatography, High Pressure Liquid; Cytokines; Down-Regulation; Epimedium; Eth | 2008 |
Effects of diesel exhaust particles on left ventricular function in isoproterenol-induced myocardial injury and healthy rats.
Topics: Air Pollutants; Animals; Disease Models, Animal; Drug Synergism; Electrocardiography; Heart; Intubat | 2008 |
Downstream defects in beta-adrenergic signaling and relation to myocyte contractility after cardioplegic arrest.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1998 |
Low-dose aspirin improves in vivo hemodynamics in conscious, chronically infarcted rats.
Topics: Adrenergic beta-Agonists; Animals; Aspirin; Drug Administration Schedule; Heart Rate; Hemodynamics; | 1998 |
Effect of left ventricular sphericity on the evolution of ventricular dysfunction in rats with diffuse isoproterenol-induced myocardial necrosis.
Topics: Adrenergic beta-Agonists; Analysis of Variance; Animals; Cardiac Output; Cardiomyopathies; Disease M | 1998 |
Myocyte recovery after mechanical circulatory support in humans with end-stage heart failure.
Topics: Adrenergic beta-Agonists; Adult; Aged; Cells, Cultured; Coronary Circulation; Electric Stimulation; | 1998 |
Overexpression of alpha1B-adrenergic receptor induces left ventricular dysfunction in the absence of hypertrophy.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Blood Pressure; Calcium; Cardiomegaly; Cells, Cult | 1998 |
Isoproterenol induced cardiovascular hypersensitiviy in nonpheochromocytoma patients with paroxysmal hyperadrenergic symptoms.
Topics: Adrenergic beta-Agonists; Adult; Case-Control Studies; Catecholamines; Female; Heart; Hemodynamics; | 1999 |
Lipocortin-1 preserves myocardial responsiveness to beta-adrenergic stimulation in rat papillary muscle.
Topics: Adrenergic beta-Agonists; Animals; Annexin A1; In Vitro Techniques; Interferon-gamma; Isoproterenol; | 1999 |
An inhibitor of poly (ADP-ribose) synthetase activity reduces contractile dysfunction and preserves high energy phosphate levels during reperfusion of the ischaemic rat heart.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Cardiotonic Agents; Diastole; Enzyme Inhibitors; He | 1999 |
Impaired lusitropy-frequency in the aging mouse: role of Ca(2+)-handling proteins and effects of isoproterenol.
Topics: Adrenergic beta-Agonists; Aging; Animals; Blood Pressure; Calcium-Binding Proteins; Calcium-Transpor | 1999 |
Altered cardiac collagen and associated changes in diastolic function of infarcted rat hearts.
Topics: Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal | 2000 |
beta-adrenergic blockade in developing heart failure: effects on myocardial inflammatory cytokines, nitric oxide, and remodeling.
Topics: Adrenergic beta-Antagonists; Animals; Cytokines; Gene Expression; Interleukin-1; Interleukin-6; Isop | 2000 |
Dyssynchronous Ca(2+) sparks in myocytes from infarcted hearts.
Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Calcium; Calcium Channels, L-Type; Calcium Sig | 2000 |
Inotropic stimulation induces cardiac dysfunction in transgenic mice expressing a troponin T (I79N) mutation linked to familial hypertrophic cardiomyopathy.
Topics: Animals; Blood Pressure; Calcium; Cardiomyopathy, Hypertrophic; Cardiotonic Agents; Cells, Cultured; | 2001 |
Reduction in myocardial collagen cross-linking parallels left ventricular dilatation in rat models of systolic chamber dysfunction.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Abdominal; Body Weight; Captopril; Collage | 2001 |
Arrhythmogenesis and contractile dysfunction in heart failure: Roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Caffeine; Calc | 2001 |
Effects of angiotensin converting enzyme inhibitor and angiotensin II type 1 receptor blocker on cardiac dysfunction induced by isoproterenol in dogs.
Topics: Adrenergic beta-Agonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting E | 2001 |
Mechanical alternans and restitution in failing SHHF rat left ventricles.
Topics: Action Potentials; Animals; Calcium; Heart Failure; Heart Rate; Hypertension; Isoproterenol; Male; R | 2002 |