isoproterenol has been researched along with Urinary Bladder, Overactive in 7 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Urinary Bladder, Overactive: Symptom of overactive detrusor muscle of the URINARY BLADDER that contracts with abnormally high frequency and urgency. Overactive bladder is characterized by the frequent feeling of needing to urinate during the day, during the night, or both. URINARY INCONTINENCE may or may not be present.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These compounds have been identified as potent and selective human beta(3)-AR agonists with improved oral bioavailability compared to the previous series." | 1.35 | Discovery of highly potent and selective biphenylacylsulfonamide-based beta3-adrenergic receptor agonists and evaluation of physical properties as potential overactive bladder therapies: part 5. ( Araki, T; Hamada, K; Hamashima, H; Hattori, K; Imamura, E; Imanishi, M; Ishikawa, H; Itou, S; Matsui, S; Matsumura, Y; Nakajima, Y; Nakano, K; Sakurai, M; Takamura, F; Toda, S; Tomishima, Y; Ueshima, K; Unami, N; Washizuka, K; Yamamoto, N; Yamamoto, T, 2009) |
| "L-carnitine treatment restored the hyporesponsiveness of isoprenaline and the hyperresponsiveness of adenosine-elicited relaxation." | 1.35 | L-carnitine treatment partially restores urinary bladder function of streptozotocin diabetic rats. ( Gur, S; Irat, AM, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hattori, K | 1 |
| Toda, S | 1 |
| Imanishi, M | 1 |
| Itou, S | 1 |
| Nakajima, Y | 1 |
| Washizuka, K | 1 |
| Araki, T | 1 |
| Hamashima, H | 1 |
| Tomishima, Y | 1 |
| Sakurai, M | 1 |
| Matsui, S | 1 |
| Imamura, E | 1 |
| Ueshima, K | 1 |
| Yamamoto, T | 1 |
| Yamamoto, N | 1 |
| Ishikawa, H | 1 |
| Nakano, K | 1 |
| Unami, N | 1 |
| Hamada, K | 1 |
| Matsumura, Y | 1 |
| Takamura, F | 1 |
| Michel, MC | 2 |
| Gur, S | 1 |
| Irat, AM | 1 |
| Otsuka, A | 1 |
| Shinbo, H | 1 |
| Hasebe, K | 1 |
| Matsumoto, R | 1 |
| Ozono, S | 1 |
| Sand, C | 1 |
| Maruyama, I | 1 |
| Goi, Y | 1 |
| Tatemichi, S | 1 |
| Maruyama, K | 1 |
| Hoyano, Y | 1 |
| Yamazaki, Y | 1 |
| Kusama, H | 1 |
| Svalø, J | 1 |
| Nordling, J | 1 |
| Bouchelouche, K | 1 |
| Andersson, KE | 1 |
| Korstanje, C | 1 |
| Bouchelouche, P | 1 |
7 other studies available for isoproterenol and Urinary Bladder, Overactive
| Article | Year |
|---|---|
Discovery of highly potent and selective biphenylacylsulfonamide-based beta3-adrenergic receptor agonists and evaluation of physical properties as potential overactive bladder therapies: part 5.
Topics: Adrenergic beta-3 Receptor Agonists; Animals; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Drug Di | 2009 |
Do β-adrenoceptor agonists induce homologous or heterologous desensitization in rat urinary bladder?
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; | 2014 |
L-carnitine treatment partially restores urinary bladder function of streptozotocin diabetic rats.
Topics: Adenosine; Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Autonomic Nervous System; Bloo | 2008 |
Effects of a novel beta(3)-adrenoceptor agonist, AJ-9677, on relaxation of the detrusor muscle: an in vitro study.
Topics: Acetates; Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Animals; Dioxoles; Female; Human | 2008 |
Effect of pre-contraction on β-adrenoceptor-mediated relaxation of rat urinary bladder.
Topics: Adrenergic beta-Agonists; Animals; Bradykinin; Carbachol; Colforsin; Dose-Response Relationship, Dru | 2009 |
Bladder selectivity of the novel β₃-agonist ritobegron (KUC-7483) explored by in vitro and in vivo studies in the rat.
Topics: Acetates; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-3 Receptor Antagonists; Adrenergic be | 2012 |
The novel β3-adrenoceptor agonist mirabegron reduces carbachol-induced contractile activity in detrusor tissue from patients with bladder outflow obstruction with or without detrusor overactivity.
Topics: Acetanilides; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Aged; Aged, 80 and over | 2013 |