isoproterenol has been researched along with Torsade de Pointes in 37 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The efficacy of isoproterenol for torsade de pointes (TdP) was evaluated in 60 dogs." | 7.68 | The efficacy of isoproterenol on quinidine induced torsade de pointes. ( Bando, S; Hamai, K; Ikefuji, H; Ito, S; Nishikado, A; Shinohara, A; Yamamoto, H; Yamamoto, K, 1991) |
| "The efficacy of isoproterenol, MgSO4 and verapamil for torsade de pointes was evaluated in 60 dogs." | 7.68 | [Efficacy of isoproterenol, magnesium sulfate and verapamil for torsade de pointes]. ( Bando, S; Hamai, K; Nishikado, A; Shinohara, A; Yamamoto, H; Yamamoto, K, 1991) |
| "Torsade de pointes is a form of polymorphic ventricular tachycardia that differs from other forms of ventricular tachycardia in its morphology, precipitating factors, and therapeutic approach." | 5.40 | The use of isoproterenol and phenytoin to reverse torsade de pointes. ( Camporesi, EM; Karlnoski, R; Mangar, D; Omar, HR; Sprenker, C, 2014) |
| "The possible occurrence of torsade de pointes in astemizole overdose, and the long elimination time of astemizole and hydroxylated metabolites, makes it necessary to maintain ECG monitoring until QT interval has returned to normal." | 5.29 | Prolonged QT interval and torsade de pointes following astemizole overdose. ( Danel, V; Dixmerias, F; Saviuc, P, 1993) |
| " We describe a severe case of refractory TdP in the setting of methadone, cocaine, hypokalemia and hypomagnesemia." | 3.91 | Severe Torsades de Pointes with acquired QT prolongation. ( Narang, A; Ozcan, C, 2019) |
| " Here, we present a case of cryptogenic underlying congenital long QT syndrome (cLQTS) successfully treated with isoproterenol, a drug contraindicated in most congenital forms of this condition." | 3.88 | Recurrent Torsades with Refractory QT Prolongation in a 54-Year-Old Man. ( Bunin, J; Guess, J; Hubel, K; Madigan, CG; Wiggins, A, 2018) |
| "The EMw was calculated as differences between the QT interval and QLVP(end) in FEAB dogs during atrial pacing, treatment with isoprenaline or atropine, body temperature changes and induction of Torsade de Pointes (TdP) in an LQT1 model." | 3.76 | The Electro-Mechanical window: a risk marker for Torsade de Pointes in a canine model of drug induced arrhythmias. ( Gallacher, DJ; Loenders, B; Somers, Y; Towart, R; van der Linde, HJ; Van Deuren, B, 2010) |
| "This study examines the effects of nicorandil, a K(+) channel opener, on transmural dispersion of repolarization (TDR) and induction of torsade de pointes (TdP) under conditions mimicking the LQT1, LQT2, and LQT3 forms of the congenital long-QT syndrome (LQTS)." | 3.70 | Effects of a K(+) channel opener to reduce transmural dispersion of repolarization and prevent torsade de pointes in LQT1, LQT2, and LQT3 models of the long-QT syndrome. ( Antzelevitch, C; Shimizu, W, 2000) |
| "The efficacy of isoproterenol, MgSO4 and verapamil for torsade de pointes was evaluated in 60 dogs." | 3.68 | [Efficacy of isoproterenol, magnesium sulfate and verapamil for torsade de pointes]. ( Bando, S; Hamai, K; Nishikado, A; Shinohara, A; Yamamoto, H; Yamamoto, K, 1991) |
| "Lidocaine was ineffective or had deleterious effects in 15 patients where electrical cardioversion required repeated use with an average of 5 times/patient." | 2.38 | Torsade de pointe. Report of 18 cases. ( Araoya, M; Chalak, W; Rifaat, M; Taha, A, 1993) |
| " In the present study, we evaluated the influences of epinephrine and isoproterenol on the onset of TdP each time D0870 was given to 6 anesthetized open-chest dogs at a dosage of 20 mg/kg, 5 times every 40 minutes, by the simultaneous measurements of surface electrocardiogram and epicardial monophasic action potential (MAP)." | 1.31 | Influences of catecholamines on the sudden death induced in dogs by an antifungal agent, D0870. ( Aldridge, A; Duffy, PA; Harada, T; Matsunaga, T; Mitsui, T; Murano, H; Shibutani, Y, 2000) |
| "The possible occurrence of torsade de pointes in astemizole overdose, and the long elimination time of astemizole and hydroxylated metabolites, makes it necessary to maintain ECG monitoring until QT interval has returned to normal." | 1.29 | Prolonged QT interval and torsade de pointes following astemizole overdose. ( Danel, V; Dixmerias, F; Saviuc, P, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 19 (51.35) | 18.2507 |
| 2000's | 11 (29.73) | 29.6817 |
| 2010's | 6 (16.22) | 24.3611 |
| 2020's | 1 (2.70) | 2.80 |
| Authors | Studies |
|---|---|
| Jackson, GG | 1 |
| Lopez, CR | 1 |
| Bermudez, ES | 1 |
| Hill, NE | 1 |
| Roden, DM | 1 |
| Ely, EW | 1 |
| Stollings, JL | 1 |
| Guess, J | 1 |
| Hubel, K | 1 |
| Wiggins, A | 1 |
| Madigan, CG | 1 |
| Bunin, J | 1 |
| Omar, HR | 1 |
| Sprenker, C | 1 |
| Karlnoski, R | 1 |
| Mangar, D | 1 |
| Camporesi, EM | 1 |
| Narang, A | 1 |
| Ozcan, C | 1 |
| Beyer, A | 1 |
| Ganti, B | 1 |
| Majkrzak, A | 1 |
| Theyyunni, N | 1 |
| Takaya, T | 1 |
| Okamoto, M | 1 |
| Yodoi, K | 1 |
| Hata, K | 1 |
| Kijima, Y | 1 |
| Nakajima, H | 1 |
| Nishikawa, Y | 1 |
| Kita, T | 1 |
| Ito, M | 1 |
| Seo, T | 1 |
| Kawashima, S | 1 |
| van der Linde, HJ | 1 |
| Van Deuren, B | 1 |
| Somers, Y | 1 |
| Loenders, B | 1 |
| Towart, R | 2 |
| Gallacher, DJ | 2 |
| Komarlu, R | 1 |
| Beerman, L | 1 |
| Freeman, D | 1 |
| Arora, G | 1 |
| Nakagawa, M | 1 |
| Ooie, T | 1 |
| Ou, B | 1 |
| Ichinose, M | 1 |
| Takahashi, N | 1 |
| Hara, M | 1 |
| Yonemochi, H | 1 |
| Saikawa, T | 1 |
| Liu, T | 1 |
| Choi, BR | 1 |
| Drici, MD | 1 |
| Salama, G | 1 |
| Antoons, G | 1 |
| Volders, PG | 2 |
| Stankovicova, T | 1 |
| Bito, V | 1 |
| Stengl, M | 1 |
| Vos, MA | 2 |
| Sipido, KR | 1 |
| Suto, F | 1 |
| Zhu, W | 1 |
| Chan, A | 1 |
| Gross, GJ | 1 |
| Van de Water, A | 1 |
| van der Linde, H | 1 |
| Hermans, AN | 1 |
| Lu, HR | 1 |
| Fabritz, L | 1 |
| Verduyn, SC | 1 |
| Gorgels, AP | 2 |
| van der Zande, J | 1 |
| Leunissen, JD | 1 |
| Wellens, HJ | 1 |
| Kawade, M | 1 |
| Ohe, T | 3 |
| Kamiya, T | 1 |
| Chalak, W | 1 |
| Taha, A | 1 |
| Araoya, M | 1 |
| Rifaat, M | 1 |
| Mei, KZ | 1 |
| Sun, AH | 1 |
| Li, BJ | 1 |
| Saviuc, P | 1 |
| Danel, V | 1 |
| Dixmerias, F | 1 |
| Morrison, Y | 1 |
| Thompson, DF | 1 |
| Laub, GW | 1 |
| Muralidharan, S | 1 |
| Janeira, L | 1 |
| Moore, RA | 1 |
| Clancy, R | 1 |
| Adkins, MS | 1 |
| Fernandez, J | 1 |
| Anderson, WA | 1 |
| McGrath, LB | 1 |
| Shimizu, W | 4 |
| Antzelevitch, C | 3 |
| Kantoch, MJ | 1 |
| Qurashi, MM | 1 |
| Bulbul, ZR | 1 |
| Watanabe, O | 1 |
| Okumura, T | 1 |
| Takeda, H | 1 |
| Nakamura, W | 1 |
| Segawa, K | 1 |
| Ito, H | 1 |
| Yoshimoto, N | 1 |
| Liu, YB | 1 |
| Chen, WJ | 1 |
| Lee, YT | 1 |
| Matsunaga, T | 1 |
| Harada, T | 1 |
| Mitsui, T | 1 |
| Murano, H | 1 |
| Duffy, PA | 1 |
| Aldridge, A | 1 |
| Shibutani, Y | 1 |
| Khan, IA | 1 |
| Stroh, JA | 1 |
| Kurita, T | 2 |
| Emori, T | 1 |
| Shimomura, K | 2 |
| Inoue, H | 1 |
| Sugimoto, T | 1 |
| Ebihara, Y | 1 |
| Nakamura, Y | 1 |
| Sakurada, H | 1 |
| Tejima, T | 1 |
| Hiyoshi, Y | 1 |
| Motomiya, T | 1 |
| Hiraoka, M | 1 |
| Yamamoto, H | 2 |
| Bando, S | 2 |
| Nishikado, A | 2 |
| Shinohara, A | 2 |
| Hamai, K | 2 |
| Yamamoto, K | 2 |
| Ikefuji, H | 1 |
| Ito, S | 1 |
| Aihara, N | 1 |
| Kamakura, S | 1 |
| Matsuhisa, M | 1 |
3 reviews available for isoproterenol and Torsade de Pointes
| Article | Year |
|---|---|
Torsade de pointe. Report of 18 cases.
Topics: Adult; Aged; Aged, 80 and over; Cardiac Pacing, Artificial; Causality; Combined Modality Therapy; El | 1993 |
Isoproterenol treatment of torsades de pointes.
Topics: Humans; Isoproterenol; Risk Factors; Torsades de Pointes | 1993 |
Long QT syndrome: diagnosis and management.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Cardiac Pacing, Artificial; Cardi | 2002 |
34 other studies available for isoproterenol and Torsade de Pointes
| Article | Year |
|---|---|
Loperamide Induced Recurrent Torsades de Pointes: A Case Report.
Topics: Adult; Analgesics, Opioid; DNA-Binding Proteins; Electrocardiography; Heart Arrest; Humans; Isoprote | 2022 |
Recurrent Torsades with Refractory QT Prolongation in a 54-Year-Old Man.
Topics: Cardiotonic Agents; Electrocardiography; Humans; Isoproterenol; KCNQ1 Potassium Channel; Long QT Syn | 2018 |
The use of isoproterenol and phenytoin to reverse torsade de pointes.
Topics: Adult; Antipsychotic Agents; Cardiotonic Agents; Drug Therapy, Combination; Electrocardiography; Eme | 2014 |
Severe Torsades de Pointes with acquired QT prolongation.
Topics: Administration, Intravenous; Anti-Arrhythmia Agents; Benzodiazepines; Chest Pain; Cocaine; Echocardi | 2019 |
A Perfect Storm: Tyrosine Kinase Inhibitor-Associated Polymorphic Ventricular Tachycardia.
Topics: Adenine; Amiodarone; Anti-Arrhythmia Agents; Antineoplastic Agents; Cardiotonic Agents; Electric Cou | 2017 |
Torsades de Pointes with QT prolongation related to donepezil use.
Topics: Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Colitis; Donepezil; Electrocardiogr | 2009 |
The Electro-Mechanical window: a risk marker for Torsade de Pointes in a canine model of drug induced arrhythmias.
Topics: Adrenergic beta-Agonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Body Temp | 2010 |
Fetal and neonatal presentation of long QT syndrome.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Electrocardiography; ERG1 Potassium Channel; Et | 2012 |
Gender differences in autonomic modulation of ventricular repolarization in humans.
Topics: Adult; Atropine; Autonomic Nervous System; Disease Susceptibility; Electrophysiologic Techniques, Ca | 2005 |
Sex modulates the arrhythmogenic substrate in prepubertal rabbit hearts with Long QT 2.
Topics: Action Potentials; Analysis of Variance; Animals; Anti-Arrhythmia Agents; Disease Models, Animal; Fe | 2005 |
Window Ca2+ current and its modulation by Ca2+ release in hypertrophied cardiac myocytes from dogs with chronic atrioventricular block.
Topics: Adrenergic beta-Agonists; Animals; Buffers; Calcium; Calcium Channels, L-Type; Cardiomegaly; Chronic | 2007 |
IKr and IKs remodeling differentially affects QT interval prolongation and dynamic adaptation to heart rate acceleration in bradycardic rabbits.
Topics: Adaptation, Physiological; Adrenergic beta-Agonists; Animals; Bradycardia; Down-Regulation; Heart Bl | 2007 |
In vivo mechanisms precipitating torsades de pointes in a canine model of drug-induced long-QT1 syndrome.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Calcium; Chromans; Disease Models, Animal; Dogs; | 2007 |
Drug-induced torsades de pointes--a form of mechano-electric feedback?
Topics: Action Potentials; Animals; Disease Models, Animal; Dogs; Electrocardiography; Feedback, Physiologic | 2007 |
The effect of flunarizine and ryanodine on acquired torsades de pointes arrhythmias in the intact canine heart.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Calcium Channels; Disease Models, Animal; Dogs; | 1995 |
Provocative testing and drug response in a patient with the long QT syndrome.
Topics: Adolescent; Drug Therapy, Combination; Electrocardiography; Epinephrine; Female; Humans; Isoproteren | 1995 |
[Classification and treatment of torsades de pointes (TdP): a report of 11 cases].
Topics: Aged; Female; Heart Block; Humans; Hypokalemia; Isoproterenol; Long QT Syndrome; Magnesium Sulfate; | 1993 |
Prolonged QT interval and torsade de pointes following astemizole overdose.
Topics: Adult; Astemizole; Drug Overdose; Electrocardiography; Female; Gastric Lavage; Half-Life; Humans; Is | 1993 |
Refractory postoperative torsades de pointes syndrome successfully treated with isoproterenol.
Topics: Atrial Fibrillation; Coronary Artery Bypass; Female; Humans; Internal Mammary-Coronary Artery Anasto | 1993 |
Cellular basis for the ECG features of the LQT1 form of the long-QT syndrome: effects of beta-adrenergic agonists and antagonists and sodium channel blockers on transmural dispersion of repolarization and torsade de pointes.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Disease Models, Animal; Dogs; Dose-R | 1998 |
A newborn with a complex congenital heart disease, atrioventricular block, and torsade de pointes ventricular tachycardia.
Topics: Cisapride; Electrocardiography; Female; Heart Block; Heart Defects, Congenital; Humans; Infant, Newb | 1998 |
Nicorandil, a potassium channel opener, abolished torsades de pointes in a patient with complete atrioventricular block.
Topics: Aged; Anesthetics, Local; Anti-Arrhythmia Agents; Bradycardia; Cardiotonic Agents; Electrocardiograp | 1999 |
Differential response of transmural dispersion of repolarization and torsade de pointes to beta-adrenergic agonists and antagonists in three models of the long QT syndrome.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Electrocardiography; Humans; Ion Cha | 1999 |
Apparent ventricular bigeminy in the congenital long QT syndrome: what is the mechanism?
Topics: Action Potentials; Adrenergic beta-Agonists; Adult; Diagnosis, Differential; Electrocardiography; Fe | 2000 |
Influences of catecholamines on the sudden death induced in dogs by an antifungal agent, D0870.
Topics: Action Potentials; Animals; Antifungal Agents; Catecholamines; Death, Sudden, Cardiac; Dogs; Electro | 2000 |
Effects of a K(+) channel opener to reduce transmural dispersion of repolarization and prevent torsade de pointes in LQT1, LQT2, and LQT3 models of the long-QT syndrome.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Cardiotonic Agents; Chromans; Cnidarian Venoms; | 2000 |
Labored breathing in an elderly woman with hypertension.
Topics: Aged; Aged, 80 and over; Bradycardia; Cardiac Complexes, Premature; Dyspnea; Electrocardiography; Fe | 1992 |
Induction of TU abnormalities in patients with torsades de pointes.
Topics: Action Potentials; Adolescent; Aged; Disopyramide; Electrocardiography; Female; Heart Conduction Sys | 1992 |
Torsades de pointes and ventricular fibrillation in a canine model of quinidine-induced QT prolongation.
Topics: Animals; Bretylium Tosylate; Cardiac Pacing, Artificial; Dogs; Female; Heart Conduction System; Isop | 1992 |
[Torsade de pointes].
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Electrocardiography | 1991 |
Association of humps on monophasic action potentials and ST-T alternans in a patient with Romano-Ward syndrome.
Topics: Action Potentials; Adult; Cardiac Pacing, Artificial; Electrocardiography; Electrophysiology; Female | 1991 |
The efficacy of isoproterenol on quinidine induced torsade de pointes.
Topics: Animals; Dogs; Electrocardiography; Electrophysiology; Isoproterenol; Quinidine; Torsades de Pointes | 1991 |
[Efficacy of isoproterenol, magnesium sulfate and verapamil for torsade de pointes].
Topics: Animals; Dogs; Drug Evaluation, Preclinical; Electrocardiography; Isoproterenol; Magnesium Sulfate; | 1991 |
Electrocardiographic and electrophysiologic studies in patients with torsades de pointe--role of monophasic action potentials.
Topics: Action Potentials; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Bradycardia; | 1990 |