isoproterenol has been researched along with Takotsubo Cardiomyopathy in 20 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Takotsubo Cardiomyopathy: A transient left ventricular apical dysfunction or ballooning accompanied by electrocardiographic (ECG) T wave inversions. This abnormality is associated with high levels of CATECHOLAMINES, either administered or endogenously secreted from a tumor or during extreme stress.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cardiac fibrosis is an essential structural remodeling associated with HF; therefore, preventing cardiac fibrosis is crucial to decelerating the progression of HF." | 5.91 | Sodium houttuyfonate against cardiac fibrosis attenuates isoproterenol-induced heart failure by binding to MMP2 and p38. ( Adu-Amankwaah, J; An, K; Cui, J; Lin, L; Song, N; Sun, H; Tan, R; Wang, M; You, Q; Yuan, J, 2023) |
| "Isoflurane treatment was started at 0, 10, 30 (early treatment) or 120 (late treatment) minutes after isoprenaline injection." | 5.46 | Early treatment with isoflurane attenuates left ventricular dysfunction and improves survival in experimental Takotsubo. ( Ali, A; Alkhoury, J; Omerovic, E; Oras, J; Redfors, B; Ricksten, SE; Seeman-Lodding, H, 2017) |
| "Cardiac fibrosis is an essential structural remodeling associated with HF; therefore, preventing cardiac fibrosis is crucial to decelerating the progression of HF." | 1.91 | Sodium houttuyfonate against cardiac fibrosis attenuates isoproterenol-induced heart failure by binding to MMP2 and p38. ( Adu-Amankwaah, J; An, K; Cui, J; Lin, L; Song, N; Sun, H; Tan, R; Wang, M; You, Q; Yuan, J, 2023) |
| "Isoflurane treatment was started at 0, 10, 30 (early treatment) or 120 (late treatment) minutes after isoprenaline injection." | 1.46 | Early treatment with isoflurane attenuates left ventricular dysfunction and improves survival in experimental Takotsubo. ( Ali, A; Alkhoury, J; Omerovic, E; Oras, J; Redfors, B; Ricksten, SE; Seeman-Lodding, H, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 12 (60.00) | 24.3611 |
| 2020's | 8 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tan, R | 1 |
| You, Q | 1 |
| Cui, J | 1 |
| Wang, M | 1 |
| Song, N | 1 |
| An, K | 1 |
| Lin, L | 1 |
| Adu-Amankwaah, J | 1 |
| Yuan, J | 1 |
| Sun, H | 1 |
| Wu, W | 1 |
| Lu, Q | 1 |
| Ma, S | 1 |
| Du, JC | 1 |
| Huynh, K | 1 |
| Duong, T | 1 |
| Pang, ZD | 1 |
| Donner, D | 1 |
| Meikle, PJ | 1 |
| Deng, XL | 1 |
| Du, XJ | 1 |
| Horowitz, JD | 1 |
| Surikow, SY | 1 |
| Madias, JE | 2 |
| Kołodzińska, A | 2 |
| Czarzasta, K | 2 |
| Szczepankiewicz, B | 2 |
| Budnik, M | 2 |
| Główczyńska, R | 2 |
| Fojt, A | 2 |
| Ilczuk, T | 2 |
| Krasuski, K | 2 |
| Borodzicz, S | 1 |
| Cudnoch-Jędrzejewska, A | 2 |
| Górnicka, B | 2 |
| Opolski, G | 2 |
| Ali, A | 4 |
| Redfors, B | 7 |
| Lundgren, J | 3 |
| Alkhoury, J | 3 |
| Oras, J | 4 |
| Gan, LM | 3 |
| Omerovic, E | 7 |
| Qi, C | 2 |
| Liu, X | 2 |
| Xiong, T | 1 |
| Wang, D | 2 |
| Folta, M | 1 |
| Arcari, L | 1 |
| Limite, LR | 1 |
| Autore, C | 1 |
| Volpe, M | 1 |
| Musumeci, MB | 1 |
| Angelini, P | 1 |
| Gamero, MT | 1 |
| Shao, Y | 4 |
| Li, X | 1 |
| Wikström, J | 1 |
| Lyon, AR | 2 |
| Oldfors, A | 1 |
| Land, S | 1 |
| Niederer, SA | 1 |
| Louch, WE | 1 |
| Røe, ÅT | 1 |
| Aronsen, JM | 1 |
| Stuckey, DJ | 1 |
| Sikkel, MB | 1 |
| Tranter, MH | 1 |
| Harding, SE | 1 |
| Smith, NP | 1 |
| Nakao, M | 1 |
| Kawaai, S | 1 |
| Nakamura, D | 1 |
| Tsunoda, A | 1 |
| Sihlbom, C | 1 |
| Thorsell, A | 1 |
| Seeman-Lodding, H | 2 |
| Ricksten, SE | 2 |
| Ståhlman, M | 1 |
| Täng, MS | 1 |
| Miljanovic, A | 1 |
| Möllmann, H | 2 |
| Troidl, C | 2 |
| Szardien, S | 2 |
| Hamm, C | 2 |
| Nef, H | 2 |
| Borén, J | 2 |
| Scharin Täng, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pathogenesis of Acute Stress Induced (Tako-tsubo) Cardiomyopathy: Energy Shut-Down or Intense Inflammation? The TERRIFIC Study[NCT02897739] | 77 participants (Actual) | Observational [Patient Registry] | 2015-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
20 other studies available for isoproterenol and Takotsubo Cardiomyopathy
| Article | Year |
|---|---|
Sodium houttuyfonate against cardiac fibrosis attenuates isoproterenol-induced heart failure by binding to MMP2 and p38.
Topics: Animals; Cardiomyopathies; Fibrosis; Heart Failure; Isoproterenol; Matrix Metalloproteinase 2; Mice; | 2023 |
Mitochondrial damage in a Takotsubo syndrome-like mouse model mediated by activation of β-adrenoceptor-Hippo signaling pathway.
Topics: Animals; Disease Models, Animal; Female; Hippo Signaling Pathway; Isoproterenol; Mice; Reactive Oxyg | 2023 |
Understanding Takotsubo syndrome: first evaluate your mouse model.
Topics: Animals; Disease Models, Animal; Isoproterenol; Mice; Reproducibility of Results; Takotsubo Cardiomy | 2023 |
Further refining of the murine model of intraperitoneal injection of isoproterenol-induced takotsubo syndrome.
Topics: Animals; Disease Models, Animal; Humans; Injections, Intraperitoneal; Isoproterenol; Mice; Takotsubo | 2023 |
Isoprenaline induced Takotsubo syndrome: Histopathological analyses of female rat hearts.
Topics: Animals; Echocardiography; Female; Humans; Isoproterenol; Male; Myocytes, Cardiac; Rats; Rats, Sprag | 2022 |
The importance of heart rate in isoprenaline-induced takotsubo-like cardiac dysfunction in rats.
Topics: Animals; Canada; Female; Heart Rate; Isoproterenol; Rats; Rats, Sprague-Dawley; Takotsubo Cardiomyop | 2020 |
Tempol prevents isoprenaline-induced takotsubo syndrome via the reactive oxygen species/mitochondrial/anti-apoptosis /p38 MAPK pathway.
Topics: Adrenergic beta-Agonists; Animals; Apoptosis; Cell Line; Cyclic N-Oxides; Free Radical Scavengers; I | 2020 |
Is modulation (desensitization) of the beta-adrenergic receptors a cause or an epiphenomenon of takotsubo syndrome?
Topics: Humans; Isoproterenol; Phosphorylation; Receptors, Adrenergic, beta; Takotsubo Cardiomyopathy | 2021 |
Toll-like receptor expression and apoptosis morphological patterns in female rat hearts with takotsubo syndrome induced by isoprenaline.
Topics: Animals; Apoptosis; Cells, Cultured; Female; Gene Expression; Heart; Isoproterenol; Myocytes, Cardia | 2018 |
[A unique case of secondary takotsubo syndrome].
Topics: Aged, 80 and over; Coronary Artery Disease; Electrocardiography; Humans; Isoproterenol; Italy; Male; | 2018 |
Effects of pretreatment with cardiostimulants and beta-blockers on isoprenaline-induced takotsubo-like cardiac dysfunction in rats.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cardiotonic Agents; Dose-Response Re | 2019 |
What can we learn from animal models of Takotsubo syndrome?
Topics: Adrenergic beta-Antagonists; Animals; Isoproterenol; Models, Animal; Rats; Takotsubo Cardiomyopathy | 2019 |
The cardioprotective effects of icariin on the isoprenaline-induced takotsubo-like rat model: Involvement of reactive oxygen species and the TLR4/NF-κB signaling pathway.
Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Echocardiography; Fibrosis; Flavonoids; Humans; | 2019 |
Contrast echocardiography reveals apparently normal coronary perfusion in a rat model of stress-induced (Takotsubo) cardiomyopathy.
Topics: Animals; Contrast Media; Coronary Circulation; Disease Models, Animal; Echocardiography; Image Proce | 2014 |
Computational modeling of Takotsubo cardiomyopathy: effect of spatially varying β-adrenergic stimulation in the rat left ventricle.
Topics: Adrenergic beta-Agonists; Animals; Calcium Signaling; Computer Simulation; Disease Models, Animal; H | 2014 |
Takotsubo cardiomyopathy during electrophysiological study with isoproterenol.
Topics: Aged; Cardiac Pacing, Artificial; Electrocardiography; Female; Humans; Isoproterenol; Takotsubo Card | 2016 |
Anaesthetic-induced cardioprotection in an experimental model of the Takotsubo syndrome - isoflurane vs. propofol.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Disease Models, Animal; Echocardiography | 2017 |
Early treatment with isoflurane attenuates left ventricular dysfunction and improves survival in experimental Takotsubo.
Topics: Adrenergic beta-Agonists; Anesthetics, Inhalation; Animals; Cardiac Output; Echocardiography; Isoflu | 2017 |
A mouse model reveals an important role for catecholamine-induced lipotoxicity in the pathogenesis of stress-induced cardiomyopathy.
Topics: Animals; Apolipoproteins B; Biopsy; Disease Models, Animal; Gene Expression Regulation; Humans; Isop | 2013 |
Novel rat model reveals important roles of β-adrenoreceptors in stress-induced cardiomyopathy.
Topics: Adrenergic beta-Agonists; Animals; Biopsy; Disease Models, Animal; Dose-Response Relationship, Drug; | 2013 |