isoproterenol has been researched along with Reperfusion Injury in 26 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rolipram failed to increase perfusate cAMP alone but dramatically increased perfusate cAMP above ISO alone." | 5.29 | Reversal of pulmonary capillary ischemia-reperfusion injury by rolipram, a cAMP phosphodiesterase inhibitor. ( Barnard, JW; Prasad, VR; Seibert, AF; Smart, DA; Strada, SJ; Taylor, AE; Thompson, WJ, 1994) |
| "Consecutive treatment of normal heart with a high dose of isoproterenol and adenosine (Iso/Ade treatment), confers strong protection against ischaemia/reperfusion injury." | 3.80 | Clinically-relevant consecutive treatment with isoproterenol and adenosine protects the failing heart against ischaemia and reperfusion. ( Bryant, SM; Dudley, DJ; Halestrap, AP; James, AF; Khaliulin, I; Suleiman, MS, 2014) |
| " At the end of treatment period, MI was induced by administering isoproterenol (ISO) or by subjecting heart to ischemia reperfusion injury (IRI)." | 3.75 | Role of Sida cordifolia L. leaves on biochemical and antioxidant profile during myocardial injury. ( Asdaq, SM; Kubavat, JB, 2009) |
| "Carvedilol, a selective alpha(1) and non-selective beta-adrenoceptor antagonist and antioxidant, has been shown to provide significant cardiac protection in animal models of myocardial ischemia." | 3.70 | Comparison of bisoprolol and carvedilol cardioprotection in a rabbit ischemia and reperfusion model. ( Chen, J; Christopher, TA; Gao, F; Gu, J; Lopez, BL; Lysko, P; Ma, XL; Ohlstein, EH; Ruffolo, RR; Yue, TL, 2000) |
| "Before ischemia/reperfusion, pial arterioles vasoconstricted to hypocapnia (-17 +/- 2%) and norepinephrine (-35 +/- 4%) and vasodilated to CO2 (37 +/- 7%) and isoproterenol (25 +/- 2%)." | 3.68 | Cerebral vasoconstriction in response to hypocapnia is maintained after ischemia/reperfusion injury in newborn pigs. ( Armstead, WM; Leffler, CW; Lowery-Smith, L; Mirro, R; Shibata, M; Zuckerman, SL, 1992) |
| "A review of the factors that oppose pulmonary edema formation (alveolar flooding) when capillary pressure is elevated are presented for a normal capillary endothelial barrier and for damaged endothelium associated with ischemia/reperfusion in rabbit, rat, and dog lungs." | 2.38 | Pulmonary edema: ischemia reperfusion endothelial injury and its reversal by c-AMP. ( Taylor, AE, 1991) |
| "Isoproterenol caused an increase in the level of cyclic AMP (rho;moles/10(5) myocytes) in the control (from 2." | 1.32 | Effects of triiodothyronine pretreatment on beta-adrenergic responses in stunned cardiac myocytes. ( Gandhi, A; He, YQ; Tse, J; Weiss, HR; Yan, L, 2003) |
| " Ws on chronic administration markedly augmented antioxidants (GSH, GSHPx, SOD, CAT) while Vit E did not stimulate the synthesis of endogenous antioxidants compared to sham." | 1.32 | Cardioprotection from ischemia and reperfusion injury by Withania somnifera: a hemodynamic, biochemical and histopathological assessment. ( Arya, DS; Bansal, P; Dinda, A; Gupta, SK; Joshi, S; Mohanty, I; Saxena, A; Talwar, KK, 2004) |
| "Rolipram failed to increase perfusate cAMP alone but dramatically increased perfusate cAMP above ISO alone." | 1.29 | Reversal of pulmonary capillary ischemia-reperfusion injury by rolipram, a cAMP phosphodiesterase inhibitor. ( Barnard, JW; Prasad, VR; Seibert, AF; Smart, DA; Strada, SJ; Taylor, AE; Thompson, WJ, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (30.77) | 18.2507 |
| 2000's | 11 (42.31) | 29.6817 |
| 2010's | 7 (26.92) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, GG | 1 |
| Cai, HQ | 1 |
| Li, YH | 1 |
| Sui, YB | 1 |
| Zhang, JS | 1 |
| Chang, JR | 1 |
| Ning, M | 1 |
| Wu, Y | 1 |
| Tang, CS | 1 |
| Qi, YF | 1 |
| Yin, XH | 1 |
| Mahmud, H | 1 |
| Candido, WM | 1 |
| van Genne, L | 1 |
| Vreeswijk-Baudoin, I | 1 |
| Yu, H | 1 |
| van de Sluis, B | 1 |
| van Deursen, J | 1 |
| van Gilst, WH | 1 |
| Silljé, HH | 1 |
| de Boer, RA | 1 |
| Shrestha, A | 1 |
| Krishnamurthy, PT | 1 |
| Thomas, P | 1 |
| Hammock, BD | 1 |
| Hwang, SH | 1 |
| Khaliulin, I | 1 |
| Halestrap, AP | 1 |
| Bryant, SM | 1 |
| Dudley, DJ | 1 |
| James, AF | 1 |
| Suleiman, MS | 1 |
| Matus, M | 1 |
| Kucerova, D | 1 |
| Kruzliak, P | 1 |
| Adameova, A | 1 |
| Doka, G | 1 |
| Turcekova, K | 1 |
| Kmecova, J | 1 |
| Kyselovic, J | 1 |
| Krenek, P | 1 |
| Kirchhefer, U | 1 |
| Mueller, FU | 1 |
| Boknik, P | 1 |
| Klimas, J | 1 |
| Zheng, XZ | 1 |
| Zhou, JL | 1 |
| Ye, J | 1 |
| Guo, PP | 1 |
| Lin, CS | 1 |
| Kubavat, JB | 1 |
| Asdaq, SM | 1 |
| Petric, S | 1 |
| Clasen, L | 1 |
| van Wessel, C | 1 |
| Geduldig, N | 1 |
| Ding, Z | 1 |
| Schullenberg, M | 1 |
| Mersmann, J | 1 |
| Zacharowski, K | 1 |
| Aller, MI | 1 |
| Schmidt, KG | 1 |
| Donner, BC | 1 |
| Chen, J | 2 |
| Petranka, J | 1 |
| Yamamura, K | 1 |
| London, RE | 1 |
| Steenbergen, C | 1 |
| Murphy, E | 1 |
| Tse, J | 1 |
| Gandhi, A | 1 |
| Yan, L | 1 |
| He, YQ | 1 |
| Weiss, HR | 1 |
| Mundiña-Weilenmann, C | 1 |
| Said, M | 1 |
| Vittone, L | 1 |
| Ferrero, P | 1 |
| Mattiazzi, A | 1 |
| Ben-Abraham, R | 1 |
| Shapira, I | 1 |
| Szold, A | 1 |
| Weinbroum, AA | 1 |
| Ralay Ranaivo, H | 1 |
| Diebolt, M | 1 |
| Andriantsitohaina, R | 1 |
| Gupta, SK | 1 |
| Mohanty, I | 1 |
| Talwar, KK | 1 |
| Dinda, A | 1 |
| Joshi, S | 1 |
| Bansal, P | 1 |
| Saxena, A | 1 |
| Arya, DS | 1 |
| Takashima, S | 1 |
| Schlidt, SA | 1 |
| Koukoulis, G | 1 |
| Sevala, M | 1 |
| Egan, TM | 3 |
| Barnard, JW | 2 |
| Seibert, AF | 3 |
| Prasad, VR | 1 |
| Smart, DA | 1 |
| Strada, SJ | 1 |
| Taylor, AE | 4 |
| Thompson, WJ | 2 |
| Khimenko, PL | 1 |
| Moore, TM | 1 |
| Wilson, PS | 1 |
| Jones, DR | 2 |
| Hoffmann, SC | 2 |
| Sellars, M | 1 |
| Kocić, I | 1 |
| Otani, H | 1 |
| Yamamura, T | 1 |
| Nakao, Y | 1 |
| Hattori, R | 1 |
| Kawaguchi, H | 1 |
| Osako, M | 1 |
| Imamura, H | 1 |
| Gao, F | 1 |
| Lopez, BL | 1 |
| Christopher, TA | 1 |
| Gu, J | 1 |
| Lysko, P | 1 |
| Ruffolo, RR | 1 |
| Ohlstein, EH | 1 |
| Ma, XL | 1 |
| Yue, TL | 1 |
| Bleiweis, MS | 1 |
| Paik, HC | 1 |
| Ciriaco, P | 1 |
| Taylor, A | 1 |
| Wilborn, WH | 1 |
| Barnard, J | 1 |
| Haynes, J | 2 |
| Adkins, WK | 1 |
| May, S | 1 |
| Mirro, R | 1 |
| Lowery-Smith, L | 1 |
| Armstead, WM | 1 |
| Shibata, M | 1 |
| Zuckerman, SL | 1 |
| Leffler, CW | 1 |
1 review available for isoproterenol and Reperfusion Injury
| Article | Year |
|---|---|
Pulmonary edema: ischemia reperfusion endothelial injury and its reversal by c-AMP.
Topics: Animals; Antioxidants; Capillary Resistance; Colforsin; Cyclic AMP; Dogs; Endothelium; Free Radicals | 1991 |
25 other studies available for isoproterenol and Reperfusion Injury
| Article | Year |
|---|---|
Ghrelin protects heart against ERS-induced injury and apoptosis by activating AMP-activated protein kinase.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Cardiotonic Agents; Cells, Cultured; Endoplasmic | 2013 |
Cardiac function and architecture are maintained in a model of cardiorestricted overexpression of the prorenin-renin receptor.
Topics: Animals; Blood Pressure; Blotting, Western; Cardiomegaly; Creatine Kinase; Echocardiography; Gene Ex | 2014 |
Soluble epoxide hydrolase inhibitor, t-TUCB, protects against myocardial ischaemic injury in rats.
Topics: Animals; Antioxidants; Benzoates; Biomarkers; Cardiotonic Agents; Epoxide Hydrolases; Heart; Heart C | 2014 |
Clinically-relevant consecutive treatment with isoproterenol and adenosine protects the failing heart against ischaemia and reperfusion.
Topics: Adenosine; Animals; Glycogen; Heart Failure; Hemodynamics; In Vitro Techniques; Isoproterenol; Male; | 2014 |
Upregulation of SERCA2a following short-term ACE inhibition (by enalaprilat) alters contractile performance and arrhythmogenicity of healthy myocardium in rat.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arrhythmias, Cardiac; Blotting, Western; Calcium | 2015 |
Cardioprotective effect of novel sulphonamides-1,3,5-triazine conjugates against ischaemic-reperfusion injury via selective inhibition of MMP-9.
Topics: Animals; Antioxidants; Cardiotonic Agents; Heart; Inhibitory Concentration 50; Isoproterenol; Male; | 2016 |
Role of Sida cordifolia L. leaves on biochemical and antioxidant profile during myocardial injury.
Topics: Animals; Antioxidants; Catalase; Creatine Kinase, MB Form; Heart; Isoproterenol; L-Lactate Dehydroge | 2009 |
In vivo electrophysiological characterization of TASK-1 deficient mice.
Topics: Adrenergic beta-Agonists; Anesthetics; Animals; Atrial Function; Baroreflex; Electric Stimulation; E | 2012 |
Gender differences in sarcoplasmic reticulum calcium loading after isoproterenol.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Egtazic Acid; Female; Isoproterenol; Male; Myocytes, Car | 2003 |
Effects of triiodothyronine pretreatment on beta-adrenergic responses in stunned cardiac myocytes.
Topics: Adrenergic beta-Agonists; Animals; Cyclic AMP; Disease Models, Animal; Heart Ventricles; Isoproteren | 2003 |
Phospholamban phosphorylation in ischemia-reperfused heart. Effect of pacing during ischemia and response to a beta-adrenergic challenge.
Topics: Adrenergic beta-Agonists; Animals; Calcium-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Is | 2003 |
Attenuation of liver ischemia-reperfusion-induced atrial dysfunction by external pacing but not by isoproterenol.
Topics: Animals; Heart Atria; In Vitro Techniques; Isoproterenol; Liver; Male; Myocardial Contraction; Pacem | 2004 |
Wine polyphenols induce hypotension, and decrease cardiac reactivity and infarct size in rats: involvement of nitric oxide.
Topics: Administration, Oral; Aldehydes; Animals; Blood Pressure; Blotting, Western; Carbachol; Coronary Cir | 2004 |
Cardioprotection from ischemia and reperfusion injury by Withania somnifera: a hemodynamic, biochemical and histopathological assessment.
Topics: Animals; Blood Pressure; Catalase; Creatine Kinase; Female; Glutathione; Glutathione Peroxidase; Hea | 2004 |
Isoproterenol reduces ischemia-reperfusion lung injury despite beta-blockade.
Topics: Adrenergic beta-Antagonists; Animals; Cyclic AMP; Isoproterenol; Lung; Male; Rats; Rats, Sprague-Daw | 2005 |
Reversal of pulmonary capillary ischemia-reperfusion injury by rolipram, a cAMP phosphodiesterase inhibitor.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adenylyl Cyclases; Animals; Capillary Permeability; Co | 1994 |
Role of calmodulin and myosin light-chain kinase in lung ischemia-reperfusion injury.
Topics: Adrenergic beta-Agonists; Animals; Calcimycin; Calcium; Calmodulin; In Vitro Techniques; Ischemia; I | 1996 |
Reduced ischemia-reperfusion injury with isoproterenol in non-heart-beating donor lungs.
Topics: Adenine Nucleotides; Adrenergic beta-Agonists; Animals; Capillary Permeability; Cell Survival; Cycli | 1997 |
Preconditioning prevents the negative inotropic action of phenylephrine in rat isolated stunned papillary muscle.
Topics: Adrenergic alpha-Antagonists; Animals; Cardiotonic Agents; Clonidine; Dioxanes; Female; Ischemic Pre | 1999 |
Insulin-like growth factor-I improves recovery of cardiac performance during reperfusion in isolated rat heart by a wortmannin-sensitive mechanism.
Topics: Androstadienes; Animals; Creatine Kinase; Dose-Response Relationship, Drug; Energy Metabolism; Enzym | 2000 |
Comparison of bisoprolol and carvedilol cardioprotection in a rabbit ischemia and reperfusion model.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Antioxidants; Bisoprolol; Carbazoles | 2000 |
Maintenance of cAMP in non-heart-beating donor lungs reduces ischemia-reperfusion injury.
Topics: Adenine Nucleotides; Adrenergic beta-Agonists; Animals; Blood Pressure; Cadaver; Capillary Permeabil | 2001 |
Reversal of increased microvascular permeability associated with ischemia-reperfusion: role of cAMP.
Topics: Animals; Bucladesine; Capillary Permeability; Colforsin; Cyclic AMP; In Vitro Techniques; Isoprotere | 1992 |
Compounds that increase cAMP prevent ischemia-reperfusion pulmonary capillary injury.
Topics: Animals; Bucladesine; Capillaries; Capillary Permeability; Colforsin; Cyclic AMP; Endothelium, Vascu | 1992 |
Cerebral vasoconstriction in response to hypocapnia is maintained after ischemia/reperfusion injury in newborn pigs.
Topics: Animals; Animals, Newborn; Arterioles; Brain Ischemia; Cerebrovascular Circulation; Dose-Response Re | 1992 |