isoproterenol has been researched along with Pheochromocytoma in 29 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Six amine, amino acid and peptide derivatives derived from 1,3-dipropyl-8-(p-carboxymethylphenyl)xanthine, a functionalized congener of 1,3-dipropyl-8-phenylxanthine, have been investigated as antagonists at A2 adenosine receptors stimulatory to adenylate cyclase in membranes from rat pheochromocytoma PC 12 cells and human platelets and at A1 adenosine receptors inhibitory to adenylate cyclase from rat fat cells." | 7.67 | Functionalized congeners of 1,3-dipropyl-8-phenylxanthine: potent antagonists for adenosine receptors that modulate membrane adenylate cyclase in pheochromocytoma cells, platelets and fat cells. ( Daly, JW; Jacobson, KA; Kirk, KL; Ukena, D, 1986) |
| "Plasma catecholamines and hemodynamics were examined in response to intravenous glucagon, yohimbine, and trimethaphan in 11 patients with pseudopheochromocytoma and a comparison group of nine normotensive and five hypertensive volunteers." | 3.74 | Sympathoadrenal function in patients with paroxysmal hypertension: pseudopheochromocytoma. ( Bentho, O; Eisenhofer, G; Geraci, MF; Goldstein, DS; Holmes, C; Pacak, K; Pechnik, S; Saleem, A; Sharabi, Y, 2007) |
| "Six amine, amino acid and peptide derivatives derived from 1,3-dipropyl-8-(p-carboxymethylphenyl)xanthine, a functionalized congener of 1,3-dipropyl-8-phenylxanthine, have been investigated as antagonists at A2 adenosine receptors stimulatory to adenylate cyclase in membranes from rat pheochromocytoma PC 12 cells and human platelets and at A1 adenosine receptors inhibitory to adenylate cyclase from rat fat cells." | 3.67 | Functionalized congeners of 1,3-dipropyl-8-phenylxanthine: potent antagonists for adenosine receptors that modulate membrane adenylate cyclase in pheochromocytoma cells, platelets and fat cells. ( Daly, JW; Jacobson, KA; Kirk, KL; Ukena, D, 1986) |
| "Metanephrines were adsorbed from plasma onto a cation-exchange column and eluted with ammoniacal methanol." | 1.29 | Determination of metanephrines in plasma by liquid chromatography with electrochemical detection. ( Armando, I; Eisenhofer, G; Goldstein, DS; Keiser, HR; Kopin, IJ; Lenders, JW, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (79.31) | 18.7374 |
| 1990's | 5 (17.24) | 18.2507 |
| 2000's | 1 (3.45) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| RIDDELL, DH | 1 |
| SCHULL, LG | 1 |
| FRIST, TF | 1 |
| BAKER, TD | 1 |
| DEBLASI, S | 1 |
| MOREY, ER | 1 |
| KENNY, AD | 1 |
| Sharabi, Y | 1 |
| Goldstein, DS | 2 |
| Bentho, O | 1 |
| Saleem, A | 1 |
| Pechnik, S | 1 |
| Geraci, MF | 1 |
| Holmes, C | 1 |
| Pacak, K | 1 |
| Eisenhofer, G | 2 |
| Snavely, MD | 2 |
| Motulsky, HJ | 1 |
| Moustafa, E | 1 |
| Mahan, LC | 1 |
| Insel, PA | 2 |
| Tsujimoto, G | 1 |
| Manger, WM | 1 |
| Hoffman, BB | 2 |
| Cases, A | 1 |
| Bono, M | 1 |
| Gaya, J | 1 |
| Jimenez, W | 1 |
| Calls, J | 1 |
| Esforzado, N | 1 |
| Rivera, F | 1 |
| Revert, L | 1 |
| Radó, J | 1 |
| Arányi, J | 1 |
| Deák, G | 1 |
| Rétai, G | 1 |
| Lenders, JW | 1 |
| Armando, I | 1 |
| Keiser, HR | 1 |
| Kopin, IJ | 1 |
| Sondergaard, SB | 1 |
| Knudsen, JH | 1 |
| Christensen, NJ | 1 |
| Lubbe, WF | 1 |
| Greenacre, JK | 1 |
| Conolly, ME | 1 |
| Carranza, MC | 1 |
| Simón, MA | 1 |
| Torres, A | 1 |
| Calle, C | 1 |
| Prokocimer, PG | 1 |
| Maze, M | 1 |
| Vickery, RG | 1 |
| Lönnroth, P | 1 |
| Wesslau, C | 1 |
| Stenström, G | 1 |
| Tisell, LE | 1 |
| Smith, U | 1 |
| Ziegler, MG | 1 |
| Ratge, D | 1 |
| Wisser, H | 1 |
| Ukena, D | 1 |
| Daly, JW | 1 |
| Kirk, KL | 1 |
| Jacobson, KA | 1 |
| Sterz, H | 1 |
| Cohen, J | 1 |
| Sapira, JD | 1 |
| Klaniecki, T | 1 |
| Ratkin, G | 1 |
| Deptalla, H | 1 |
| Wiegershausen, B | 1 |
| Lydtin, H | 1 |
| Warndorff, JA | 1 |
| Loggie, JM | 1 |
| Van Maanen, EF | 1 |
| von Egidy, H | 1 |
| Fujino, T | 1 |
| Mashiba, H | 1 |
| Lurvey, A | 1 |
| Yussin, A | 1 |
| DeQuattro, V | 1 |
| Prichard, BN | 1 |
| Ross, EJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pheochromocytoma Randomised Study Comparing Adrenoreceptor Inhibiting Agents for Preoperative Treatment[NCT01379898] | Phase 4 | 134 participants (Actual) | Interventional | 2011-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for isoproterenol and Pheochromocytoma
| Article | Year |
|---|---|
Clinical usefulness of the beta-adrenergic antagonists.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Angina Pectoris; Antihypertensive Agents; Anx | 1978 |
[Beta-receptor-blocking agents and their current clinical significance].
Topics: Adrenal Gland Neoplasms; Amino Alcohols; Angina Pectoris; Anilides; Arrhythmias, Cardiac; Blood Pres | 1968 |
[Beta-receptor-blocking agents and anesthesia].
Topics: Adrenal Gland Neoplasms; Anesthesia; Angina Pectoris; Arrhythmias, Cardiac; Asthma; Cardiomyopathy, | 1969 |
The autonomic nervous system and some aspects of the use of autonomic drugs in children. II.
Topics: Adrenergic beta-Antagonists; Aortic Valve Stenosis; Asthma; Autonomic Agents; Bronchitis; Cardiomyop | 1972 |
[Catecholamine cardiopathy].
Topics: Adrenal Gland Neoplasms; Adult; Animals; Catecholamines; Cerebrovascular Disorders; Electrocardiogra | 1972 |
24 other studies available for isoproterenol and Pheochromocytoma
| Article | Year |
|---|---|
Experience with pheochromocytoma in 21 patients: use of dichloroisoproterenol hydrochloride for cardiac arrhythmia.
Topics: Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Dibucaine; Heart Conducti | 1963 |
[THE USE OF DICHLOROISOPROTERENOL, A "BETA" ADRENOLYTIC DRUG, IN 2 CASES OF PHEOCHROMOCYTOMA].
Topics: Adrenergic Antagonists; Arrhythmias, Cardiac; Blood Circulation; Blood Pressure; Blood Pressure Dete | 1964 |
EFFECTS OF CATECHOLAMINES ON URINARY CALCIUM AND PHOSPHORUS IN INTACT AND PARATHYROIDECTOMIZED RATS.
Topics: Calcium; Calcium, Dietary; Catecholamines; Creatine; Creatinine; Epinephrine; Hypoparathyroidism; Is | 1964 |
Sympathoadrenal function in patients with paroxysmal hypertension: pseudopheochromocytoma.
Topics: Adrenal Glands; Adult; Baroreflex; Blood Pressure Monitoring, Ambulatory; Epinephrine; Female; Gluca | 2007 |
beta-Adrenergic receptor subtypes in the rat renal cortex. Selective regulation of beta 1-adrenergic receptors by pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Animals; Binding, Competitive; Epinephrine; Hydroxydopamines; Iodocyanopind | 1982 |
Desensitization of beta-adrenergic receptors by pheochromocytoma.
Topics: Adipose Tissue; Adrenal Gland Neoplasms; Animals; Body Weight; Cell Membrane; Cyclic AMP; Energy Int | 1984 |
Reversible decrease of surface beta 2-adrenoceptor number and response in lymphocytes of patients with pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Adrenergic beta-Antagonists; Adult; Aged; Case-Control Studies; Catecholami | 1995 |
[Pseudophaeochromocytoma (hypertensive crisis as a result of beta receptor hypersensitivity?)].
Topics: Adrenal Gland Neoplasms; Adrenergic beta-Antagonists; Catecholamines; Drug Hypersensitivity; Humans; | 1993 |
Determination of metanephrines in plasma by liquid chromatography with electrochemical detection.
Topics: Adrenal Gland Neoplasms; Chromatography, High Pressure Liquid; Epinephrine; Humans; Isoproterenol; M | 1993 |
Regulation of cAMP in a lymphocyte preparation isolated from peripheral venous blood in human subjects: the significance of residual thrombocytes, noradrenaline and prostaglandins.
Topics: Adrenergic beta-Agonists; Aged; Analysis of Variance; Biomarkers; Blood Platelets; Cells, Cultured; | 1998 |
Desensitization of the beta-adrenoceptor of lymphocytes from normal subjects and patients with phaeochromocytoma: studies in vivo.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adrenal Gland Neoplasms; Albuterol; Cyclic AMP; Humans; In Vitr | 1978 |
Chronic and endogenous regulation of insulin receptors by catecholamines in adipocytes from patients with a phaeochromocytoma.
Topics: Adipose Tissue; Adrenal Gland Neoplasms; Adult; Female; Glycerol; Humans; Insulin; Isoproterenol; Ma | 1990 |
Mechanism for desensitization of beta-adrenergic receptor-stimulated lipolysis in adipocytes from rats harboring pheochromocytoma.
Topics: Adipose Tissue; Adrenal Gland Neoplasms; Animals; Cyclic AMP; Isoproterenol; Kinetics; Lipolysis; Ph | 1988 |
Reduced insulin binding to human fat cells following beta-adrenergic stimulation--experimental evidence and studies in patients with a phaeochromocytoma.
Topics: Adipose Tissue; Adrenal Gland Neoplasms; Adrenergic beta-Antagonists; Adult; Aged; Catecholamines; F | 1985 |
Subtype-selective down-regulation of rat renal cortical alpha- and beta-adrenergic receptors by catecholamines.
Topics: Animals; Epinephrine; Isoproterenol; Kidney Cortex; Kinetics; Male; Membranes; Norepinephrine; Pheoc | 1985 |
Alpha- and beta-adrenergic receptor activity in circulating blood cells of patients with phaeochromocytoma: effects of adrenalectomy.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Blood Platelets; Cyclic AMP; Dihydroalprenolol; Epine | 1986 |
Functionalized congeners of 1,3-dipropyl-8-phenylxanthine: potent antagonists for adenosine receptors that modulate membrane adenylate cyclase in pheochromocytoma cells, platelets and fat cells.
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenal Gland Neoplasms; Animals; Blood Platelets; Cell Line; Cyc | 1986 |
[Clinical studies with a new beta receptor blocking agent from the indole series (LB 46)].
Topics: Adolescent; Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Asthma; Atrial Fibrillation; Atrial | 1970 |
Role of endocrine factors in the pathogenesis of cardiac hypertrophy.
Topics: Acromegaly; Animals; Body Weight; Cardiomegaly; Catecholamines; Disease Models, Animal; Growth Hormo | 1974 |
"Non-pheochromocytoma".
Topics: Adrenal Gland Neoplasms; Adult; Arteriovenous Fistula; Asthma; Celiac Disease; Child, Preschool; Dia | 1970 |
The response of the sweat glands to -adrenergic stimulation.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Dermatitis, Atopic; | 1972 |
[What is assured in treatment with beta receptor blockaders?].
Topics: Acetanilides; Adrenergic beta-Antagonists; Alprenolol; Amino Alcohols; Cresols; Heart Diseases; Huma | 1972 |
Pseudopheochromocytoma after self-administered isoproterenol.
Topics: Adult; Epinephrine; Female; Humans; Isoproterenol; Norepinephrine; Pheochromocytoma; Substance-Relat | 1973 |
Use of propranolol in conjunction with alpha receptor blocking drugs in pheochromocytoma.
Topics: Blood Pressure; Epinephrine; Humans; Isoproterenol; Norepinephrine; Phenoxybenzamine; Pheochromocyto | 1966 |