isoproterenol has been researched along with Ocular Hypertension in 5 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Ocular Hypertension: A condition in which the intraocular pressure is elevated above normal and which may lead to glaucoma.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intraocular pressure was measured by pneumatonometry." | 1.30 | Repeated topical administration of fenoterol in rabbit reverses its initial ocular hypotensive effect and decreases sensitivity of adenylyl cyclase in ciliary processes to stimulatory agents. ( Cepelík, J; Hynie, S, 1997) |
| "Intraocular pressure was measured in ocular hypertonic rabbits which were induced by infusing 20% NaCl or 5% glucose solution." | 1.30 | Ocular hypotensive and vasodilative effects of two beta-adrenergic blockers with intrinsic sympathomimetic activity. ( Chen, IJ; Hong, SJ; Wu, KY, 1998) |
| " The dosage forms were tested on intraocular hypertensive-induced rabbits." | 1.29 | Poly(epsilon-caprolactone) nanocapsules in carteolol ophthalmic delivery. ( Hoffman, M; Maincent, P; Marchal-Heussler, L; Sirbat, D, 1993) |
| "Detomidine was found to be a partial agonist producing about 43% of maximum inhibition obtained by medetomidine." | 1.28 | Ocular hypotensive effects of medetomidine and its analogs. ( Elko, EE; Jin, Y; Wilson, S; Yorio, T, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pech, B | 1 |
| Chetoni, P | 1 |
| Saettone, MF | 1 |
| Duval, O | 1 |
| Benoit, JP | 1 |
| Marchal-Heussler, L | 1 |
| Sirbat, D | 1 |
| Hoffman, M | 1 |
| Maincent, P | 1 |
| Cepelík, J | 1 |
| Hynie, S | 1 |
| Hong, SJ | 1 |
| Wu, KY | 1 |
| Chen, IJ | 1 |
| Jin, Y | 1 |
| Wilson, S | 1 |
| Elko, EE | 1 |
| Yorio, T | 1 |
5 other studies available for isoproterenol and Ocular Hypertension
| Article | Year |
|---|---|
Preliminary evaluation of a series of amphiphilic timolol prodrugs: possible evidence for transscleral absorption.
Topics: Absorption; Animals; Cell Membrane Permeability; Cornea; Disease Models, Animal; Esters; Evaluation | 1993 |
Poly(epsilon-caprolactone) nanocapsules in carteolol ophthalmic delivery.
Topics: Animals; Blood Pressure; Capsules; Carteolol; Chemical Phenomena; Chemistry, Physical; Heart Rate; H | 1993 |
Repeated topical administration of fenoterol in rabbit reverses its initial ocular hypotensive effect and decreases sensitivity of adenylyl cyclase in ciliary processes to stimulatory agents.
Topics: Adenylyl Cyclases; Administration, Topical; Adrenergic beta-Agonists; Animals; Ciliary Body; Colfors | 1997 |
Ocular hypotensive and vasodilative effects of two beta-adrenergic blockers with intrinsic sympathomimetic activity.
Topics: Adrenergic beta-Antagonists; Animals; Aorta; Butanones; Cell Line; Ciliary Body; Cyclic AMP; Eugenol | 1998 |
Ocular hypotensive effects of medetomidine and its analogs.
Topics: Adenylyl Cyclase Inhibitors; Adrenergic alpha-Agonists; Animals; Cats; Ciliary Body; Dose-Response R | 1991 |