isoproterenol has been researched along with Obesity in 193 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Impaired leptin signalling in obesity is increasingly implicated in cardiovascular pathophysiology." | 7.73 | Leptin repletion restores depressed {beta}-adrenergic contractility in ob/ob mice independently of cardiac hypertrophy. ( Barouch, LA; Berkowitz, DE; Emala, CW; Gonzalez, DR; Hare, JM; Khan, SA; Lee, K; Minhas, KM; O'Donnell, CP; Phan, AC; Raju, SV; Saliaris, AP; Skaf, MW; Tejani, AD, 2005) |
| "The adenosine receptors were studied by using the adenosine antagonist 1,3-[3H]dipropyl-8-cyclopentylxanthine." | 5.28 | Attenuated adenosine-sensitivity and decreased adenosine-receptor number in adipocyte plasma membranes in human obesity. ( Hreniuk, SP; Kaartinen, JM; LaNoue, KF; Martin, LF; Ohisalo, JJ; Ranta, S, 1991) |
| "Adenosine is a local hormone or a retaliatory metabolite that executes its effect via a plasma membrane receptor, the R-site." | 5.27 | Attenuated adenosine R-site effect in adipocytes in obesity. ( Huhtaniemi, IT; Ohisalo, JJ; Ranta, S, 1986) |
| "Obesity is characterised by increased triacylglycerol storage in adipose tissue." | 5.13 | Effect of beta-adrenergic stimulation on whole-body and abdominal subcutaneous adipose tissue lipolysis in lean and obese men. ( Blaak, EE; Frayn, KN; Goossens, GH; Jocken, JW; Pakbiers, MT; Saris, WH; Stegen, J; van Baak, M; van Hees, AM, 2008) |
| "Beta-adrenergic receptor agonist, isoproterenol, and an adenylate cyclase activator, forskolin, at a single dose significantly reduced insulin resistance consistent with a decrease in total and phospho-p53 levels in insulin and non-insulin metabolic target tissues." | 3.83 | Obesity-induced p53 activation in insulin-dependent and independent tissues is inhibited by beta-adrenergic agonist in diet-induced obese rats. ( Cheraghpour, M; Ghorbani, A; Homayounfar, R; Jeddi-Tehrani, M; Pourvali, K; Soltani, SR; Zand, H, 2016) |
| "Curcumin, an active component derived from dietary spice turmeric (Curcuma longa), has been demonstrated antihyperglycemic, antiinflammatory and hypocholesterolemic activities in obesity and diabetes." | 3.78 | Curcumin attenuates lipolysis stimulated by tumor necrosis factor-α or isoproterenol in 3T3-L1 adipocytes. ( Kong, PR; Li, Y; Li, YX; Wu, JF; Xie, XY, 2012) |
| "In the search for potent and selective human beta3-adrenergic receptor (AR) agonists as potential drugs for the treatment of obesity and noninsulin-dependent (type II) diabetes, we prepared a novel series of phenoxypropanolamine derivatives containing the thiourea moiety and evaluated their biological activities at human beta3-, beta2-, and beta1-ARs." | 3.75 | Discovery of novel thiourea derivatives as potent and selective beta3-adrenergic receptor agonists. ( Hayakawa, M; Kawazoe, S; Maruyama, T; Matsui, T; Ohta, M; Onda, K; Seki, N; Suzuki, T; Takasu, T, 2009) |
| "Obesity is accompanied by impaired fasting glycerol release, lower HSL protein expression, and serine phosphorylation." | 3.74 | Hormone-sensitive lipase serine phosphorylation and glycerol exchange across skeletal muscle in lean and obese subjects: effect of beta-adrenergic stimulation. ( Blaak, EE; Goossens, GH; Jocken, JW; Kiens, B; Roepstorff, C; Saris, WH; van Baak, M; van der Baan, P, 2008) |
| "Impaired leptin signalling in obesity is increasingly implicated in cardiovascular pathophysiology." | 3.73 | Leptin repletion restores depressed {beta}-adrenergic contractility in ob/ob mice independently of cardiac hypertrophy. ( Barouch, LA; Berkowitz, DE; Emala, CW; Gonzalez, DR; Hare, JM; Khan, SA; Lee, K; Minhas, KM; O'Donnell, CP; Phan, AC; Raju, SV; Saliaris, AP; Skaf, MW; Tejani, AD, 2005) |
| " This study tested the hypothesis that an increased training volume was required to attenuate obesity-related reductions in isolated heart responsiveness to isoproterenol." | 3.73 | A comparison of two exercise training programs on cardiac responsiveness to beta-stimulation in obesity. ( Carroll, JF; Thaden, JJ; Wright, AM, 2005) |
| "Obesity-related decreases in responsiveness of the isolated heart to isoproterenol are not associated with alterations in beta-receptor density and affinity." | 3.71 | beta-Adrenoceptor density and adenylyl cyclase activity in obese rabbit hearts. ( Carroll, JF; Kyser, CK; Martin, MM, 2002) |
| " Basal lipolysis, maximal lipolytic responses to isoprenaline (beta-AR agonist), dobutamine and procaterol (beta1- and beta2-AR agonists, respectively) as well as maximal antilipolytic effects of epinephrine or UK-14304 (alpha2-AR agonist) were similar before and after weight reduction." | 3.70 | Regional and gender variations in adipose tissue lipolysis in response to weight loss. ( Alméras, N; Després, JP; Imbeault, P; Lacaille, M; Langin, D; Mauriège, P; Tremblay, A, 1999) |
| " Obesity enhanced the heart rate response to beta-adrenergic stimulation by isoproterenol in the LD, but not CO group." | 3.70 | Composition of dietary fat affects blood pressure and insulin responses to dietary obesity in the dog. ( Borne, AT; Monteiro, MP; Truett, AA; West, DB, 1998) |
| "To determine whether obesity alters responsiveness to vasoactive drugs, we compared the cardiovascular effects of angiotensin, phenylephrine and isoproterenol in unanesthetized age-matched control and obese Oscai rats." | 3.68 | Renovascular beta adrenergic hypersensitivity and hyperinsulinemia in rats with dietary-induced obesity. ( Buñag, RD; Krizsan, D; Tomita, T, 1990) |
| "Adenylate cyclase activity and its modulation by guanine nucleotides and isoproterenol were assessed in adipocyte membranes of mice with mutations causing different genetic obesity syndromes." | 3.67 | Effect of the genetic background and specific mutation on adenylate cyclase activity in obesity syndromes. ( Bégin-Heick, N; Coleman, DL, 1988) |
| "To analyze B-cell mechanisms in obesity, we measured the relationship (slope of potentiation) between glucose levels and acute insulin responses (AIR) to isoproterenol or arginine in nondiabetic subjects ranging from lean to markedly obese." | 3.67 | Relationship of islet function to insulin action in human obesity. ( Beard, JC; Halter, JB; Porte, D; Wallum, BJ; Ward, WK, 1987) |
| "To examine the possibility that the decrease of hyperinsulinemia and blood pressure in obesity associated with physical training is mediated via adaptations in the adrenergic nervous system, a pure beta-adrenergic agonist (isoproterenol) or an alpha-adrenergic antagonist (phentolamine) was infused before and during an oral glucose tolerance test before and after physical training." | 3.66 | Effects of physical training on adrenergic sensitivity in obesity. ( Björntorp, P; Feurle, GE; Krotkiewski, M; Mandroukas, K; Morgan, L; Sjöström, L; Smith, U; von Schenck, H; William-Olsson, T, 1983) |
| " However, in lean men, the dose-response relationship between isoproterenol and glycerol was shifted towards the left (P < 0." | 2.73 | Dissociation between adipose nitric oxide synthase expression and tissue metabolism. ( Adams, F; Boschmann, M; Engeli, S; Franke, G; Gorzelniak, K; Janke, J; Jordan, J; Luft, FC, 2007) |
| "Obesity is associated with a blunted beta-adrenoceptor-mediated lipolysis and fat oxidation." | 2.73 | Association of a beta-2 adrenoceptor (ADRB2) gene variant with a blunted in vivo lipolysis and fat oxidation. ( Arner, P; Blaak, EE; Jocken, JW; Saris, WH; Schiffelers, S; van Baak, MA, 2007) |
| "The isoproterenol-induced increase in EGC was higher after the training." | 2.71 | Dynamic strength training improves insulin sensitivity and functional balance between adrenergic alpha 2A and beta pathways in subcutaneous adipose tissue of obese subjects. ( Berlan, M; Hejnova, J; Klimcakova, E; Lafontan, M; Langin, D; Majercik, M; Moro, C; Polak, J; Stich, V; Viguerie, N, 2005) |
| "Obesity is an important risk factor for diabetes mellitus (DM) which is a major global health problem." | 1.72 | Effects of Isoprenaline on ventricular myocyte shortening and Ca ( Howarth, FC; Qureshi, MA; Sultan, A, 2022) |
| "Obesity is characterized by a blunted lipolytic response in abdominal subcutaneous adipose tissue (SAT) and low circulating vitamin D levels." | 1.51 | Vitamin D release across abdominal adipose tissue in lean and obese men: The effect of ß-adrenergic stimulation. ( Blaak, EE; Goossens, GH; Jocken, JWE; Pramono, A, 2019) |
| "The metabolic syndrome is associated with prolonged stress and hyperactivity of the sympathetic nervous system and afflicted subjects are prone to develop cardiovascular disease." | 1.43 | The Role of Reactive Oxygen Species in β-Adrenergic Signaling in Cardiomyocytes from Mice with the Metabolic Syndrome. ( Andersson, DC; Fauconnier, J; Jardemark, K; Katz, A; Lanner, JT; Llano-Diez, M; Sinclair, J; Westerblad, H; Yamada, T; Zhang, SJ; Zong, M, 2016) |
| "Obesity was caused by high-fat diet for 12 weeks in rats." | 1.43 | Reduced lipolysis response to adipose afferent reflex involved in impaired activation of adrenoceptor-cAMP-PKA-hormone sensitive lipase pathway in obesity. ( Chen, Q; Ding, L; Kang, YM; Li, YH; Ren, XS; Zhang, F; Zhao, MX; Zhu, GQ, 2016) |
| "Obesity is a worldwide pandemic associated with high incidence of cardiovascular disease." | 1.43 | Saturated high-fat diet-induced obesity increases adenylate cyclase of myocardial β-adrenergic system and does not compromise cardiac function. ( Adorni, CS; Cicogna, AC; da Silva, DC; de Campos, DH; de Deus, AF; de Oliveira, SM; de Tomasi, LC; Okoshi, K; Padovani, CR; Sant'Ana, PG; Vileigas, DF, 2016) |
| "The obesity was not accompanied by changes in protein expression of G protein subunit alpha (Gsα) and βA receptors (β1AR and β2AR)." | 1.42 | Cardiac Dysfunction Induced by Obesity Is Not Related to β-Adrenergic System Impairment at the Receptor-Signalling Pathway. ( Cicogna, AC; de Campos, DH; de Tomasi, LC; Ferron, AJ; Jacobsen, BB; Leopoldo, AS; Lima-Leopoldo, AP; Luvizotto, Rde A; Sant'Ana, PG, 2015) |
| "Obesity is an important risk factor for atrial fibrillation (AF)." | 1.38 | Adipocytes modulate the electrophysiology of atrial myocytes: implications in obesity-induced atrial fibrillation. ( Chen, JH; Chen, SA; Chen, YC; Chen, YJ; Lin, YK, 2012) |
| "Gliclazide or saline was given q12 h for 48 h to rats received isoprenaline." | 1.38 | Blockers of sulfonylureas receptor 1 subunits may lead to cardiac protection against isoprenaline-induced injury in obese rats. ( Bao, Y; Shuyuan, L; Sun, X; Yang, W; Yerong, Y, 2012) |
| "Obesity is a common and rapidly growing health problem today." | 1.35 | Human mesenteric adipose tissue plays unique role versus subcutaneous and omental fat in obesity related diabetes. ( Abrams, GA; Aprahamian, CJ; Chen, M; Clements, RH; Harmon, CM; Yang, YK, 2008) |
| "Hyperinsulinemia in obesity has been attributed to insulin oversecretion by pancreatic beta-cells." | 1.33 | The dual effect of isoproterenol on insulin release is suppressed in pancreatic islets from hypothalamic obese rats. ( da Rocha, DN; de Freitas Mathias, PC; Grassiolli, S; Gravena, C; Marçal, AC; Puzzi, MA; Scomparin, DX, 2006) |
| "Octopamine treatment resulted in a 19% decrease in body weight gain, when compared to the 177 g gained by controls during the same period." | 1.32 | Moderate weight-lowering effect of octopamine treatment in obese Zucker rats. ( Bour, S; Carpéné, C; Prévot, D; Visentin, V, 2003) |
| "Glycerol release was measured and used as lipolytic index." | 1.31 | Influence of heredity for obesity on adipocyte lipolysis in lean and obese subjects. ( Hellström, L; Reynisdottir, S, 2000) |
| "Childhood obesity is associated with several abnormalities of the GH axis, including decreased spontaneous secretion, decreased response to exogenous secretagogues, and altered pulsatile pattern of secretion." | 1.31 | Effects of growth hormone treatment in obese prepubertal boys. ( Danielsson, P; Elimam, A; Kamel, A; Marcus, C; Norgren, S, 2000) |
| "This obesity is also characterised by alterations of the beta-adrenergic signaling pathway." | 1.31 | Impaired beta-adrenergic signaling pathway in white adipocytes of suckling fa/fa Zucker rats: a defect in receptor coupling. ( Adli, H; Bazin, R; Diot-Dupuy, F; Ferré, P; Mory, G; Wiel, M, 2001) |
| " Contractile responsiveness in the IH was determined using a modified Langendorff preparation to evaluate the dose-response relationship between isoproterenol and 1) peak developed pressure/g of left ventricular wet weight and 2) maximal rate of pressure development (+dP/dt/P)." | 1.30 | Reduced cardiac contractile responsiveness to isoproterenol in obese rabbits. ( Carroll, JF; Cockrell, K; Hester, RL; Jones, AE; Mizelle, HL; Reinhart, GA, 1997) |
| "Glycerol release was measured and used as a lipolytic index." | 1.30 | Lipolytic catecholamine resistance linked to alpha 2-adrenoceptor sensitivity--a metabolic predictor of weight loss in obese subjects. ( Hagström-Toft, E; Hellström, L; Reynisdottir, S; Rössner, S, 1997) |
| "Leptin is an adipocyte hormone involved in the regulation of energy homeostasis." | 1.30 | Leptin impairs metabolic actions of insulin in isolated rat adipocytes. ( Ertl, J; Gerl, M; Müller, G; Preibisch, G, 1997) |
| " Analysis of dose-response curves for different beta-agonists revealed that (i) both the basal and the maximally stimulated activity of AC were 2-fold lower in fa/fa rats than in Fa/fa rats; (ii) BRL37344 and CGP12177 (beta 3 agonists) were less potent in fa/fa than in Fa/fa rats (Kact." | 1.29 | Early alterations in the brown adipose tissue adenylate cyclase system of pre-obese Zucker rat fa/fa pups: decreased G-proteins and beta 3-adrenoceptor activities. ( Bazin, R; Charon, C; Diot-Dupuy, F; Emorine, LJ; Krief, S; Strosberg, AD, 1995) |
| "The adenosine receptors were studied by using the adenosine antagonist 1,3-[3H]dipropyl-8-cyclopentylxanthine." | 1.28 | Attenuated adenosine-sensitivity and decreased adenosine-receptor number in adipocyte plasma membranes in human obesity. ( Hreniuk, SP; Kaartinen, JM; LaNoue, KF; Martin, LF; Ohisalo, JJ; Ranta, S, 1991) |
| " The dose-response relationships of the alpha 2- and beta-selective agents clonidine and isoproterenol were not appreciably changed by caloric restriction." | 1.27 | Adrenergic regulation of lipolysis in abdominal adipocytes of obese subjects during caloric restriction: reversal of catecholamine action caused by relief of endogenous inhibition. ( Fischer, B; Kather, H; Schlierf, G; Wieland, E; Wirth, A, 1985) |
| "Adenosine is a local hormone or a retaliatory metabolite that executes its effect via a plasma membrane receptor, the R-site." | 1.27 | Attenuated adenosine R-site effect in adipocytes in obesity. ( Huhtaniemi, IT; Ohisalo, JJ; Ranta, S, 1986) |
| "Starvation was associated with an approx." | 1.27 | Antilipolytic effects of N6-phenylisopropyladenosine and prostaglandin E2 in fat-cells of obese volunteers before and during energy restriction. ( Fischer, B; Kather, H; Schlierf, G; Wieland, E, 1985) |
| "Obesity is a circumstance characterized in the dog fat cell by a modification of the balance between alpha-2 and beta receptors." | 1.26 | Alpha-2 adrenergic antilipolytic effect in dog fat cells: incidence of obesity and adipose tissue localization. ( Berlan, M; Carpene, C; Dang-Tran, L; Lafontan, M, 1982) |
| " One group, 5-6 months of age, was divided into three subgroups: the control, group I, was fed usual laboratory chow; group II was subjected to dietary restriction (3 months); group III was fed the usual diet with chronic administration of insulin (1." | 1.26 | Alpha-adrenergic responses in rabbit white fat cells: the influence of obesity and food restriction. ( Lafontan, M, 1981) |
| " 2 Blood pressure and heart rate recordings made before dosing was started showed the streptozotocin-treated animals to have a significantly reduced heart rate and increased pulse pressure as compared with controls." | 1.26 | Effect of experimental diabetes, food deprivation and genetic obesity on the sensitivity of pithed rats to autonomic agents. ( Foy, JM; Lucas, PD, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 55 (28.50) | 18.7374 |
| 1990's | 57 (29.53) | 18.2507 |
| 2000's | 49 (25.39) | 29.6817 |
| 2010's | 24 (12.44) | 24.3611 |
| 2020's | 8 (4.15) | 2.80 |
| Authors | Studies |
|---|---|
| Bloom, JD | 1 |
| Dutia, MD | 1 |
| Johnson, BD | 1 |
| Wissner, A | 1 |
| Burns, MG | 1 |
| Largis, EE | 1 |
| Dolan, JA | 1 |
| Claus, TH | 1 |
| Maruyama, T | 1 |
| Seki, N | 1 |
| Onda, K | 1 |
| Suzuki, T | 1 |
| Kawazoe, S | 1 |
| Hayakawa, M | 1 |
| Matsui, T | 1 |
| Takasu, T | 1 |
| Ohta, M | 1 |
| Kim, SO | 1 |
| Sakchaisri, K | 1 |
| Asami, Y | 1 |
| Ryoo, IJ | 1 |
| Choo, SJ | 1 |
| Yoo, ID | 1 |
| Soung, NK | 1 |
| Kim, YS | 1 |
| Jang, JH | 1 |
| Kim, BY | 1 |
| Ahn, JS | 1 |
| Limberg, JK | 1 |
| Johansson, RE | 1 |
| Carter, KJ | 1 |
| Peltonen, GL | 1 |
| Harrell, JW | 1 |
| Kellawan, JM | 1 |
| Eldridge, MW | 1 |
| Sebranek, JJ | 1 |
| Walker, BJ | 1 |
| Schrage, WG | 1 |
| Rydén, M | 2 |
| Andersson, DP | 1 |
| Kotopouli, MI | 1 |
| Stenberg, E | 1 |
| Näslund, E | 1 |
| Thorell, A | 1 |
| Sørensen, TIA | 1 |
| Arner, P | 12 |
| Sultan, A | 1 |
| Qureshi, MA | 1 |
| Howarth, FC | 1 |
| McElhanon, KE | 1 |
| Huff, TC | 1 |
| Hirenallur-Shanthappa, D | 1 |
| Miller, RA | 1 |
| Christoforou, N | 1 |
| Pramono, A | 1 |
| Jocken, JWE | 1 |
| Goossens, GH | 5 |
| Blaak, EE | 13 |
| Higashida, K | 1 |
| Takeuchi, N | 1 |
| Inoue, S | 2 |
| Hashimoto, T | 1 |
| Nakai, N | 1 |
| Ziqubu, K | 1 |
| Muller, CJF | 1 |
| Dludla, PV | 1 |
| Mthembu, SXH | 1 |
| Obonye, N | 1 |
| Louw, J | 1 |
| Kappo, AP | 1 |
| Silvestri, S | 1 |
| Orlando, P | 1 |
| Tiano, L | 1 |
| Mazibuko-Mbeje, SE | 1 |
| Rogal, J | 1 |
| Binder, C | 1 |
| Kromidas, E | 1 |
| Roosz, J | 1 |
| Probst, C | 1 |
| Schneider, S | 1 |
| Schenke-Layland, K | 1 |
| Loskill, P | 1 |
| Chang, SH | 1 |
| Jang, J | 1 |
| Oh, S | 1 |
| Yoon, JH | 1 |
| Jo, DG | 1 |
| Yun, UJ | 1 |
| Park, KW | 1 |
| Bussey, CT | 1 |
| Thaung, HPA | 1 |
| Hughes, G | 1 |
| Bahn, A | 1 |
| Lamberts, RR | 1 |
| Drareni, K | 1 |
| Ballaire, R | 1 |
| Barilla, S | 1 |
| Mathew, MJ | 1 |
| Toubal, A | 1 |
| Fan, R | 1 |
| Liang, N | 1 |
| Chollet, C | 1 |
| Huang, Z | 1 |
| Kondili, M | 1 |
| Foufelle, F | 1 |
| Soprani, A | 1 |
| Roussel, R | 1 |
| Gautier, JF | 1 |
| Alzaid, F | 1 |
| Treuter, E | 1 |
| Venteclef, N | 2 |
| Boqué, N | 1 |
| de la Iglesia, R | 1 |
| de la Garza, AL | 1 |
| Milagro, FI | 1 |
| Olivares, M | 1 |
| Bañuelos, O | 1 |
| Soria, AC | 1 |
| Rodríguez-Sánchez, S | 1 |
| Martínez, JA | 3 |
| Campión, J | 2 |
| Avila, PR | 1 |
| Marques, SO | 1 |
| Luciano, TF | 1 |
| Vitto, MF | 1 |
| Engelmann, J | 1 |
| Souza, DR | 1 |
| Pereira, SV | 1 |
| Pinho, RA | 1 |
| Lira, FS | 1 |
| De Souza, CT | 1 |
| Geng, B | 1 |
| Cai, B | 1 |
| Liao, F | 1 |
| Zheng, Y | 1 |
| Zeng, Q | 1 |
| Fan, X | 1 |
| Gong, Y | 1 |
| Yang, J | 1 |
| Cui, QH | 1 |
| Tang, C | 1 |
| Xu, GH | 1 |
| Bae, J | 1 |
| Ricciardi, CJ | 1 |
| Esposito, D | 1 |
| Komarnytsky, S | 1 |
| Hu, P | 1 |
| Curry, BJ | 1 |
| Brown, PL | 1 |
| Gao, Z | 1 |
| Biggerstaff, JP | 1 |
| Chen, J | 1 |
| Zhao, L | 1 |
| Ferron, AJ | 1 |
| Jacobsen, BB | 1 |
| Sant'Ana, PG | 2 |
| de Campos, DH | 2 |
| de Tomasi, LC | 2 |
| Luvizotto, Rde A | 1 |
| Cicogna, AC | 2 |
| Leopoldo, AS | 1 |
| Lima-Leopoldo, AP | 1 |
| Goto, T | 1 |
| Naknukool, S | 1 |
| Yoshitake, R | 1 |
| Hanafusa, Y | 1 |
| Tokiwa, S | 1 |
| Li, Y | 2 |
| Sakamoto, T | 1 |
| Nitta, T | 1 |
| Kim, M | 1 |
| Takahashi, N | 1 |
| Yu, R | 1 |
| Daiyasu, H | 1 |
| Seno, S | 1 |
| Matsuda, H | 1 |
| Kawada, T | 1 |
| Zand, H | 1 |
| Homayounfar, R | 1 |
| Cheraghpour, M | 1 |
| Jeddi-Tehrani, M | 1 |
| Ghorbani, A | 1 |
| Pourvali, K | 1 |
| Soltani, SR | 1 |
| Vileigas, DF | 1 |
| de Deus, AF | 1 |
| da Silva, DC | 1 |
| Adorni, CS | 1 |
| de Oliveira, SM | 1 |
| Okoshi, K | 1 |
| Padovani, CR | 1 |
| Ding, L | 1 |
| Zhang, F | 1 |
| Zhao, MX | 1 |
| Ren, XS | 1 |
| Chen, Q | 1 |
| Li, YH | 1 |
| Kang, YM | 1 |
| Zhu, GQ | 1 |
| Llano-Diez, M | 1 |
| Sinclair, J | 1 |
| Yamada, T | 1 |
| Zong, M | 1 |
| Fauconnier, J | 1 |
| Zhang, SJ | 1 |
| Katz, A | 1 |
| Jardemark, K | 1 |
| Westerblad, H | 1 |
| Andersson, DC | 1 |
| Lanner, JT | 1 |
| Guénantin, AC | 1 |
| Briand, N | 1 |
| Capel, E | 1 |
| Dumont, F | 1 |
| Morichon, R | 1 |
| Provost, C | 1 |
| Stillitano, F | 1 |
| Jeziorowska, D | 1 |
| Siffroi, JP | 1 |
| Hajjar, RJ | 1 |
| Fève, B | 1 |
| Hulot, JS | 1 |
| Collas, P | 1 |
| Capeau, J | 1 |
| Vigouroux, C | 1 |
| Yang, YK | 1 |
| Chen, M | 1 |
| Clements, RH | 1 |
| Abrams, GA | 1 |
| Aprahamian, CJ | 1 |
| Harmon, CM | 1 |
| Moro, C | 3 |
| Pasarica, M | 1 |
| Elkind-Hirsch, K | 1 |
| Redman, LM | 1 |
| Getty-Kaushik, L | 1 |
| Viereck, JC | 1 |
| Goodman, JM | 1 |
| Guo, Z | 1 |
| LeBrasseur, NK | 1 |
| Richard, AM | 1 |
| Flanagan, JN | 1 |
| Yaney, GC | 1 |
| Hamilton, JA | 1 |
| Tornheim, K | 1 |
| Mulumba, M | 1 |
| Jossart, C | 1 |
| Granata, R | 1 |
| Gallo, D | 1 |
| Escher, E | 1 |
| Ghigo, E | 1 |
| Servant, MJ | 1 |
| Marleau, S | 1 |
| Ong, H | 1 |
| Wedellová, Z | 1 |
| Dietrich, J | 1 |
| Siklová-Vítková, M | 1 |
| Kološtová, K | 1 |
| Kováčiková, M | 1 |
| Dušková, M | 1 |
| Brož, J | 1 |
| Vedral, T | 1 |
| Stich, V | 8 |
| Polák, J | 2 |
| Hickner, RC | 2 |
| Kemeny, G | 1 |
| Clark, PD | 1 |
| Galvin, VB | 1 |
| McIver, KL | 1 |
| Evans, CA | 1 |
| Carper, MJ | 1 |
| Garry, JP | 1 |
| Bizzarri, A | 1 |
| Essers, Y | 1 |
| Cleutjens, JP | 1 |
| Konings, E | 1 |
| Jocken, JW | 5 |
| Cajlakovic, M | 1 |
| Ribitsch, V | 1 |
| Clément, K | 1 |
| Oliver, P | 1 |
| Caimari, A | 1 |
| Díaz-Rúa, R | 1 |
| Palou, A | 1 |
| Bao, Y | 1 |
| Sun, X | 1 |
| Yerong, Y | 1 |
| Shuyuan, L | 1 |
| Yang, W | 1 |
| Lin, YK | 1 |
| Chen, YC | 1 |
| Chen, JH | 1 |
| Chen, SA | 1 |
| Chen, YJ | 1 |
| Xie, XY | 1 |
| Kong, PR | 1 |
| Wu, JF | 1 |
| Li, YX | 1 |
| Harant, I | 3 |
| Marion-Latard, F | 1 |
| Crampes, F | 4 |
| de Glisezinski, I | 4 |
| Berlan, M | 10 |
| Rivière, D | 4 |
| Hauner, H | 1 |
| Röhrig, K | 1 |
| Siffert, W | 1 |
| Barakat, H | 1 |
| Privette, J | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Metabolic Signalling in Muscle- and Adipose Tissue Following Insulin Withdrawal and Growth Hormone Injection in Type I Diabetes Mellitus, a Clinical Experimental Study.[NCT02077348] | 9 participants (Actual) | Interventional | 2014-05-31 | Completed | |||
| Regulation of Lipolysis by Insulin in Skeletal Muscle and Adipose Tissue in Type 2 Diabetes[NCT01680133] | 20 participants (Actual) | Observational | 2007-06-30 | Completed | |||
| Effect of Aerobic Exercise Associated With Abdominal Laser Therapy in Lipolytic Activity, Profile and Inflammatory Markers[NCT03462537] | 36 participants (Actual) | Interventional | 2016-11-20 | Terminated | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for isoproterenol and Obesity
| Article | Year |
|---|---|
Advances in medicine.
Topics: Acute Kidney Injury; Asthma; Blindness; Catecholamines; Contraceptives, Oral; Coronary Disease; Guan | 1968 |
[Diagnosis and treatment of pulmonary artery embolism].
Topics: Age Factors; Angiography; Anticoagulants; Carbon Dioxide; Electrocardiography; Extracorporeal Circul | 1971 |
12 trials available for isoproterenol and Obesity
| Article | Year |
|---|---|
Aerobic exercise training improves atrial natriuretic peptide and catecholamine-mediated lipolysis in obese women with polycystic ovary syndrome.
Topics: Adult; Atrial Natriuretic Factor; Body Mass Index; Catecholamines; Exercise; Exercise Therapy; Femal | 2009 |
Influences of AT1 receptor blockade on tissue metabolism in obese men.
Topics: Adipose Tissue; Adult; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Cross-Over Studi | 2006 |
Dynamic strength training improves insulin sensitivity and functional balance between adrenergic alpha 2A and beta pathways in subcutaneous adipose tissue of obese subjects.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Recept | 2005 |
Association of a beta-2 adrenoceptor (ADRB2) gene variant with a blunted in vivo lipolysis and fat oxidation.
Topics: Adipose Tissue; Adrenergic beta-Agonists; Adult; Anthropometry; Energy Metabolism; Female; Genetic V | 2007 |
Dissociation between adipose nitric oxide synthase expression and tissue metabolism.
Topics: Adipose Tissue; Adrenergic beta-Agonists; Adult; Body Weight; Enzyme Inhibitors; Gene Expression Reg | 2007 |
Effect of beta-adrenergic stimulation on whole-body and abdominal subcutaneous adipose tissue lipolysis in lean and obese men.
Topics: Adipose Tissue; Adrenergic beta-Agonists; Adult; Body Composition; Body Mass Index; Fasting; Fatty A | 2008 |
Impaired endothelium-dependent vasodilation in overweight and obese adult humans is not limited to muscarinic receptor agonists.
Topics: Acetylcholine; Adult; Aged; Body Mass Index; Bradykinin; Dose-Response Relationship, Drug; Endotheli | 2008 |
Pima Indian males have lower beta-adrenergic sensitivity than Caucasian males.
Topics: Adrenergic beta-Agonists; Adult; Arizona; Cardiotonic Agents; Female; Humans; Indians, North America | 1998 |
Regional differences in adrenoceptor binding and fat cell lipolysis in obese, postmenopausal women.
Topics: Adipocytes; Adipose Tissue; Adrenergic beta-Agonists; Aged; Cell Size; Female; Humans; Isoproterenol | 1998 |
In situ lipolytic responses to isoproterenol and physiological stressors are similar in obese Pima Indians and Caucasians.
Topics: Adrenergic beta-Agonists; Arizona; Exercise; Humans; Indians, North American; Isoproterenol; Linear | 1998 |
Synergism between insulin and low concentrations of isoproterenol in the stimulation of leptin release by cultured human adipose tissue.
Topics: Adipocytes; Adrenergic beta-Antagonists; Adult; Catecholamines; Dexamethasone; Drug Synergism; Femal | 2000 |
The effect of exercise training on beta-adrenergic stimulation of fat metabolism in obese men.
Topics: Adrenergic beta-Agonists; Adult; Body Composition; Energy Metabolism; Exercise; Glycerol; Humans; Is | 2001 |
179 other studies available for isoproterenol and Obesity
| Article | Year |
|---|---|
Disodium (R,R)-5-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]-amino] propyl]-1,3-benzodioxole-2,2-dicarboxylate (CL 316,243). A potent beta-adrenergic agonist virtually specific for beta 3 receptors. A promising antidiabetic and antiobesity agent.
Topics: Adipose Tissue; Adrenergic beta-Agonists; Animals; Diabetes Mellitus, Type 2; Hypoglycemic Agents; L | 1992 |
Discovery of novel thiourea derivatives as potent and selective beta3-adrenergic receptor agonists.
Topics: Adrenergic Agonists; Adrenergic beta-3 Receptor Antagonists; Animals; Diabetes Mellitus, Type 2; Hum | 2009 |
Illudins C2 and C3 stimulate lipolysis in 3T3-L1 adipocytes and suppress adipogenesis in 3T3-L1 preadipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; CCAAT-Enhancer-Binding Protein-alpha; CCAAT-Enhance | 2014 |
Preserved β-adrenergic-mediated vasodilation in skeletal muscle of young adults with obesity despite shifts in cyclooxygenase and nitric oxide synthase.
Topics: Adrenergic beta-Agonists; Adult; Blood Vessels; Cyclooxygenase Inhibitors; Female; Humans; Isoproter | 2022 |
Lipolysis defect in people with obesity who undergo metabolic surgery.
Topics: Bariatric Surgery; Body Mass Index; Body Weight; Catecholamines; Cross-Sectional Studies; Gastric By | 2022 |
Effects of Isoprenaline on ventricular myocyte shortening and Ca
Topics: Animals; Caffeine; Diabetes Mellitus; Diabetes Mellitus, Type 2; Isoproterenol; Myocytes, Cardiac; O | 2022 |
Increased circulating progranulin is not sufficient to induce cardiac dysfunction or supraventricular arrhythmia.
Topics: Animals; Atrial Fibrillation; Electrocardiography; Heart Rate; Isoproterenol; Mice; Obesity; Progran | 2023 |
Vitamin D release across abdominal adipose tissue in lean and obese men: The effect of ß-adrenergic stimulation.
Topics: Abdominal Fat; Adrenergic beta-Agonists; Adult; Dihydroxycholecalciferols; Humans; Infusions, Intrav | 2019 |
Iron deficiency attenuates catecholamine‑stimulated lipolysis via downregulation of lipolysis‑related proteins and glucose utilization in 3T3‑L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Catecholamines; Deferoxamine; Down-Regulation; Glucose; Iron; Iro | 2020 |
Impact of Isoorientin on Metabolic Activity and Lipid Accumulation in Differentiated Adipocytes.
Topics: 3T3-L1 Cells; Adenosine Triphosphate; Adipocytes; AMP-Activated Protein Kinase Kinases; Animals; Dio | 2020 |
WAT-on-a-chip integrating human mature white adipocytes for mechanistic research and pharmaceutical applications.
Topics: Adipocytes, White; Adipose Tissue, White; Adrenergic beta-Agonists; Animals; Biological Transport; C | 2020 |
Nrf2 induces Ucp1 expression in adipocytes in response to β3-AR stimulation and enhances oxygen consumption in high-fat diet-fed obese mice.
Topics: Adipocytes; Adipose Tissue, Brown; Animals; Cell Line; Diet, High-Fat; Dioxoles; Energy Metabolism; | 2021 |
Cardiac β-adrenergic responsiveness of obese Zucker rats: The role of AMPK.
Topics: Adrenergic beta-Agonists; AMP-Activated Protein Kinases; Animals; Heart; Isoproterenol; Male; Myocar | 2018 |
GPS2 Deficiency Triggers Maladaptive White Adipose Tissue Expansion in Obesity via HIF1A Activation.
Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue, White; Animals; Blotting, Western; Body Temperature; Calor | 2018 |
Prevention of diet-induced obesity by apple polyphenols in Wistar rats through regulation of adipocyte gene expression and DNA methylation patterns.
Topics: Adipocytes; Animals; Anti-Obesity Agents; Aquaporins; Diet; Diet, High-Fat; DNA Methylation; Gene Ex | 2013 |
Resveratrol and fish oil reduce catecholamine-induced mortality in obese rats: role of oxidative stress in the myocardium and aorta.
Topics: Animals; Antioxidants; Aorta; Catecholamines; Dietary Fats; Dietary Supplements; Fish Oils; Isoprote | 2013 |
Increase or decrease hydrogen sulfide exert opposite lipolysis, but reduce global insulin resistance in high fatty diet induced obese mice.
Topics: Adipocytes; Alkynes; Animals; Blood Glucose; Carrier Proteins; Cystathionine gamma-Lyase; Cysteine; | 2013 |
Activation of pattern recognition receptors in brown adipocytes induces inflammation and suppresses uncoupling protein 1 expression and mitochondrial respiration.
Topics: Adipocytes; Adipose Tissue, Brown; Animals; Cell Line; Cytokines; Diet, High-Fat; Electron Transport | 2014 |
Cardiac Dysfunction Induced by Obesity Is Not Related to β-Adrenergic System Impairment at the Receptor-Signalling Pathway.
Topics: Adiposity; Adrenergic beta-Agonists; Animals; Blood Pressure; Blotting, Western; Calcium; Diet, High | 2015 |
Proinflammatory cytokine interleukin-1β suppresses cold-induced thermogenesis in adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue, White; Adrenergic beta-Agonists; Animals; Cell Line; Cold | 2016 |
Obesity-induced p53 activation in insulin-dependent and independent tissues is inhibited by beta-adrenergic agonist in diet-induced obese rats.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Blotting, Western; Colforsin; Cyclic AMP; Insu | 2016 |
Saturated high-fat diet-induced obesity increases adenylate cyclase of myocardial β-adrenergic system and does not compromise cardiac function.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Arrhythmias, Cardiac; Autopsy; Diet, High-Fat; | 2016 |
Reduced lipolysis response to adipose afferent reflex involved in impaired activation of adrenoceptor-cAMP-PKA-hormone sensitive lipase pathway in obesity.
Topics: Adipocytes; Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dietary Fats; Isoproterenol; | 2016 |
The Role of Reactive Oxygen Species in β-Adrenergic Signaling in Cardiomyocytes from Mice with the Metabolic Syndrome.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Cardiomyopathies; Diet, High-Fat; Electric Stimulation; | 2016 |
Functional Human Beige Adipocytes From Induced Pluripotent Stem Cells.
Topics: Adipocytes, Beige; Adipogenesis; Adipose Tissue; Adrenergic beta-Agonists; Animals; Cell Transplanta | 2017 |
Human mesenteric adipose tissue plays unique role versus subcutaneous and omental fat in obesity related diabetes.
Topics: Adiponectin; CD36 Antigens; Diabetes Mellitus, Type 2; Fatty Acids; Gene Expression Regulation; Glyc | 2008 |
Mice deficient in phosphofructokinase-M have greatly decreased fat stores.
Topics: Adipocytes; Adipose Tissue; Animals; Body Weight; Female; Glycerophosphates; Glycolysis; Insulin; In | 2010 |
GPR103b functions in the peripheral regulation of adipogenesis.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Adult; Animals; Cell Differentiation; Cells, Cultured; Gene | 2010 |
Adiponectin inhibits spontaneous and catecholamine-induced lipolysis in human adipocytes of non-obese subjects through AMPK-dependent mechanisms.
Topics: Adipocytes; Adiponectin; AMP-Activated Protein Kinases; Humans; Isoproterenol; Lipolysis; Male; Midd | 2011 |
In vivo nitric oxide suppression of lipolysis in subcutaneous abdominal adipose tissue is greater in obese than lean women.
Topics: Adult; Fasting; Fatty Acids, Nonesterified; Female; Humans; Isoproterenol; Lipolysis; Microdialysis; | 2012 |
Increased adipose tissue oxygen tension in obese compared with lean men is accompanied by insulin resistance, impaired adipose tissue capillarization, and inflammation.
Topics: Adipose Tissue; Angiotensin II; Humans; Hyperoxia; Inflammation; Insulin Resistance; Isoproterenol; | 2011 |
Cold exposure down-regulates adiponutrin/PNPLA3 mRNA expression and affects its nutritional regulation in adipose tissues of lean and obese Zucker rats.
Topics: Adipocytes; Adipose Tissue; Animal Nutrition Sciences; Animals; Blood Glucose; Body Weight; Cells, C | 2012 |
Blockers of sulfonylureas receptor 1 subunits may lead to cardiac protection against isoprenaline-induced injury in obese rats.
Topics: Animals; ATP-Binding Cassette Transporters; Cell Size; Gene Expression Regulation; Gliclazide; Heart | 2012 |
Adipocytes modulate the electrophysiology of atrial myocytes: implications in obesity-induced atrial fibrillation.
Topics: Action Potentials; Adipocytes; Animals; Atrial Fibrillation; Heart Atria; Isoproterenol; Male; Myocy | 2012 |
Curcumin attenuates lipolysis stimulated by tumor necrosis factor-α or isoproterenol in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Carrier Proteins; Curcuma; Curcumin; Diabetes Mellitus, Type 2; D | 2012 |
Effect of a long-duration physical exercise on fat cell lipolytic responsiveness to adrenergic agents and insulin in obese men.
Topics: Abdomen; Adipocytes; Adrenergic Agonists; Adult; Brimonidine Tartrate; Epinephrine; Exercise; Humans | 2002 |
Effects of the G-protein beta3 subunit 825T allele on adipogenesis and lipolysis in cultured human preadipocytes and adipocytes.
Topics: Adipocytes; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Alleles; Body Mass Index; Catecholami | 2002 |
Differences in the lipolytic function of adipose tissue preparations from Black American and Caucasian women.
Topics: Adipocytes; Adipose Tissue; Adrenergic beta-Agonists; Adult; Black People; Female; Humans; Isoproter | 2002 |
Cardiovascular vagosympathetic activity in rats with ventromedial hypothalamic obesity.
Topics: Animals; Atropine; Blood Glucose; Blood Pressure; Body Weight; Cardiovascular System; Epinephrine; F | 2003 |
Lipolytic and nutritive blood flow response to beta-adrenoceptor stimulation in situ in subcutaneous abdominal adipose tissue in obese men.
Topics: Abdominal Wall; Adipocytes; Adipose Tissue; Adrenergic beta-Agonists; Albuterol; Dobutamine; Dose-Re | 2003 |
Pinpoint fat relief?
Topics: Aminophylline; Cardiotonic Agents; Humans; Injections, Subcutaneous; Isoproterenol; Obesity; United | 2003 |
Isolated heart responsiveness to beta-simulation after exercise training in obesity.
Topics: Adrenergic beta-Agonists; Animals; Disease Models, Animal; Exercise Therapy; Female; Humans; Isoprot | 2003 |
SIGNIFICANCE OF THE DYNAMIC PRESSURE-VOLUME CURVE IN SUBJECTS WITH AND WITHOUT OBSTRUCTIVE RESPIRATORY DISEASE.
Topics: Biomedical Research; Bronchodilator Agents; Carcinoma, Bronchogenic; Humans; Isoproterenol; Kymograp | 1963 |
[Effects of catecholamines on human preadipocyte proliferation and differentiation].
Topics: Adipocytes; Catecholamines; Cell Differentiation; Cell Proliferation; Epinephrine; Humans; Isoproter | 2003 |
Regulation of lipolysis and lipoprotein lipase after weight loss in obese, postmenopausal women.
Topics: Adipocytes; Adipose Tissue; Adrenergic beta-Agonists; Aged; Body Composition; Cholesterol, HDL; Ener | 2004 |
Moderate weight-lowering effect of octopamine treatment in obese Zucker rats.
Topics: Adipocytes; Animals; Blood Glucose; Body Weight; Fatty Acids, Nonesterified; Food Deprivation; Gluco | 2003 |
Ketoconazole, an antifungal agent, protects against adiposity induced by a cafeteria diet.
Topics: Adipocytes; Adipose Tissue; Analysis of Variance; Animals; Antifungal Agents; Body Composition; Eati | 2004 |
Isoproterenol decreases leptin release from rat and human adipose tissue through posttranscriptional mechanisms.
Topics: Adipose Tissue; Adrenergic beta-Agonists; Animals; Blotting, Northern; Cycloheximide; Isoproterenol; | 2005 |
A comparison of two exercise training programs on cardiac responsiveness to beta-stimulation in obesity.
Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Body Composition; Dose-Response Relationship, Dru | 2005 |
Leptin repletion restores depressed {beta}-adrenergic contractility in ob/ob mice independently of cardiac hypertrophy.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Age Factors; Animals; Blotting, Western; Calcium; Cardi | 2005 |
Training enhances ANP lipid-mobilizing action in adipose tissue of overweight men.
Topics: Adipose Tissue; Adrenergic beta-Agonists; Adult; Atrial Natriuretic Factor; Exercise; France; Humans | 2005 |
Adipocyte lipases and defect of lipolysis in human obesity.
Topics: Adipocytes; Adipose Tissue; Adult; Female; Gene Expression Regulation, Enzymologic; Humans; Isoprote | 2005 |
Effects of dexamethasone on primarily cultured newly differentiated rat adipocytes from different adipose tissue regions.
Topics: Adipocytes; Adipose Tissue; Animals; Anti-Inflammatory Agents; Cell Differentiation; Cells, Cultured | 1993 |
Lipolysis in intraabdominal adipose tissues of obese women and men.
Topics: Abdomen; Adipocytes; Adipose Tissue; Body Composition; Body Constitution; Body Mass Index; Body Weig | 1993 |
Acute regulation of plasma leptin by isoprenaline in lean and obese fasted subjects.
Topics: Adrenergic beta-Agonists; Adult; Body Mass Index; Fasting; Glycerol; Humans; Isoproterenol; Leptin; | 2006 |
Reduced PDE4 expression and activity contributes to enhanced catecholamine-induced cAMP accumulation in adipocytes from FOXC2 transgenic mice.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipocytes; Adipose Tissue; Adrenergic beta-Agonists; Animals; | 2006 |
The dual effect of isoproterenol on insulin release is suppressed in pancreatic islets from hypothalamic obese rats.
Topics: Animals; Animals, Newborn; Blood Glucose; Hyperinsulinism; In Vitro Techniques; Insulin; Insulin Sec | 2006 |
Effects of histamine on triglyceride breakdown in mouse adipocytes.
Topics: Adipocytes; Adrenergic beta-Agonists; Amine Oxidase (Copper-Containing); Animals; Carcinogens; Hista | 2007 |
An evaluation of mesotherapy solutions for inducing lipolysis and treating cellulite.
Topics: Adipocytes; Adipose Tissue; Aminophylline; Cells, Cultured; Drug Evaluation, Preclinical; Glycerol; | 2008 |
Exercise training decreases in vitro stimulated lipolysis in a visceral (mesenteric) but not in the retroperitoneal fat depot of high-fat-fed rats.
Topics: Adipocytes; Adrenergic beta-Agonists; Animals; Biomarkers; Body Composition; Carrier Proteins; Cells | 2008 |
Hormone-sensitive lipase serine phosphorylation and glycerol exchange across skeletal muscle in lean and obese subjects: effect of beta-adrenergic stimulation.
Topics: Adrenergic beta-Agonists; Adult; Blood Pressure; Body Mass Index; Glycerol; Humans; Isoproterenol; K | 2008 |
Short-term beta-adrenergic regulation of leptin, adiponectin and interleukin-6 secretion in vivo in lean and obese subjects.
Topics: Adiponectin; Adrenergic beta-Agonists; Adult; Case-Control Studies; Forearm; Humans; Interleukin-6; | 2008 |
Cyclic nucleotides in diabetes mellitus and obesity.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Animals; Cyclic AMP; Cyclic GMP; Diabetes Melli | 1980 |
Thyroid hormone regulation of the catecholamine effects in human adipose tissue.
Topics: Adipose Tissue; Cyclic AMP; Humans; Hyperthyroidism; Isoproterenol; Lipolysis; Norepinephrine; Obesi | 1981 |
Impairment of hormone-stimulated cardiac adenylate cyclase activity in the genetically obese (fa/fa) Zucker rat.
Topics: Adenylyl Cyclases; Age Factors; Animals; Disease Models, Animal; Enzyme Activation; Food Deprivation | 1981 |
Alpha-adrenergic responses in rabbit white fat cells: the influence of obesity and food restriction.
Topics: Adipose Tissue; Adrenocorticotropic Hormone; Animals; Diet, Reducing; Epinephrine; In Vitro Techniqu | 1981 |
Alpha-2 adrenergic antilipolytic effect in dog fat cells: incidence of obesity and adipose tissue localization.
Topics: Adipose Tissue; Animals; Clonidine; Dogs; Epinephrine; Isoproterenol; Lipolysis; Obesity; Prazosin; | 1982 |
Abnormal brown adipose composition and beta-adrenoceptor binding in obese Zucker rats.
Topics: Adipose Tissue, Brown; Animals; Body Weight; Dihydroalprenolol; Epinephrine; Isoproterenol; Lipolysi | 1982 |
[Comparative study of adrenaline-induced lipolysis of human deltoid and trochanter adipose tissue].
Topics: Adipose Tissue; Adult; Aged; Anthropometry; Epinephrine; Female; Humans; Isoproterenol; Lipolysis; M | 1983 |
The cardiac inotropic response to secretin is lower in genetically obese (fa/fa) than in lean (fa/?) Zucker rats.
Topics: Adenylyl Cyclases; Animals; Dose-Response Relationship, Drug; Enzyme Activation; Isoproterenol; Male | 1983 |
Central activation and peripheral function of sympatho-adrenal and cardiovascular systems in the Zucker rat.
Topics: Adrenal Glands; Animals; Blood Pressure; Cardiovascular System; Dihydroalprenolol; Electric Stimulat | 1984 |
Effects of physical training on adrenergic sensitivity in obesity.
Topics: Adult; Blood Glucose; Blood Pressure; C-Peptide; Female; Glucose Tolerance Test; Heart Rate; Humans; | 1983 |
Influence of obesity on the antilipolytic effect of insulin in isolated human fat cells obtained before and after glucose ingestion.
Topics: Adipose Tissue; Adult; Dose-Response Relationship, Drug; Female; Glucose; Glycerol; Humans; Insulin; | 1984 |
The interaction of guanine nucleotides with the adenylate cyclase complex in white adipocyte membranes of lean and obese (ob/ob) mice.
Topics: Adenylyl Cyclases; Adenylyl Imidodiphosphate; Adipose Tissue; Animals; Enzyme Activation; Guanine Nu | 1984 |
Hyperinsulinemia in rats with hypothalamic obesity: effects of autonomic drugs and glucose.
Topics: Animals; Atropine; Epinephrine; Female; Glucose; Hyperinsulinism; Isoproterenol; Obesity; Phentolami | 1983 |
Effects of a very-low-calorie diet on adrenergic responsiveness in human adipose tissue.
Topics: Adipose Tissue; Adult; Clonidine; Diet, Reducing; Female; Humans; Isoproterenol; Lipolysis; Middle A | 1984 |
Isoproterenol-stimulated C-peptide and insulin secretion in diabetic and nonobese normal subjects: decreased hepatic extraction of endogenous insulin in diabetes.
Topics: Adult; Aged; C-Peptide; Diabetes Mellitus; Humans; Insulin; Insulin Secretion; Isoproterenol; Kineti | 1980 |
Regional blood flow in genetically--obese rats during nonshivering thermogenesis.
Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Body Temperature Regulation; Coronary Circulation; F | 1982 |
Membrane fluidity and adenylate cyclase activity in genetically obese mice.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Cell Membrane; Isoproterenol; Kinetics; Membrane Fluidit | 1980 |
Beta-adrenergic responsiveness of adenylate cyclase in human adipocyte plasma membranes in obesity and after massive weight reduction.
Topics: Adenylyl Cyclases; Adipose Tissue; Adult; Analysis of Variance; Cell Fractionation; Cell Membrane; F | 1995 |
Acute cold-induced suppression of ob (obese) gene expression in white adipose tissue of mice: mediation by the sympathetic system.
Topics: Adipose Tissue; Adipose Tissue, Brown; Adrenergic beta-Agonists; Animals; Base Sequence; Body Weight | 1995 |
Beta 3-adrenergic activation of adenylyl cyclase in mouse white adipocytes: modulation by GTP and effect of obesity.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipocytes; Adipose Tissue; Adrenergic beta-Agonists; Al | 1995 |
Beta-adrenergically mediated thermogenic and heart rate responses: effect of obesity and weight loss.
Topics: Adult; Body Temperature Regulation; Energy Metabolism; Heart Rate; Humans; Isoproterenol; Male; Nore | 1995 |
Beta-adrenergic stimulation and abdominal subcutaneous fat blood flow in lean, obese, and reduced-obese subjects.
Topics: Abdominal Muscles; Adipose Tissue; Adult; Atenolol; Body Composition; Diet; Humans; Injections, Intr | 1995 |
Beta-adrenergic stimulation of energy expenditure and forearm skeletal muscle metabolism in lean and obese men.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Atenolol; Body Temperature Regulation; | 1994 |
beta-Adrenergic stimulation of skeletal muscle metabolism in relation to weight reduction in obese men.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Atenolol; Body Composition; Fatty Acid | 1994 |
Multiple lipolysis defects in the insulin resistance (metabolic) syndrome.
Topics: Adipose Tissue; Aged; Clonidine; Dose-Response Relationship, Drug; Humans; Insulin Resistance; Isopr | 1994 |
In vitro lipid synthesis in human adipose tissue from three abdominal sites.
Topics: Abdomen; Adipose Tissue; Adult; Diglycerides; Female; Humans; Isoproterenol; Lipids; Lipolysis; Male | 1993 |
Early alterations in the brown adipose tissue adenylate cyclase system of pre-obese Zucker rat fa/fa pups: decreased G-proteins and beta 3-adrenoceptor activities.
Topics: Adenylyl Cyclases; Adipose Tissue, Brown; Adrenergic beta-Antagonists; Animals; Animals, Suckling; B | 1995 |
Regulation of lipolysis in fat cells of obese women during long-term hypocaloric diet.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adipocytes; Adrenergic beta-Agonists; Adult; Brimonidine Tar | 1996 |
Adipocyte lipolysis in normal weight subjects with obesity among first-degree relatives.
Topics: Adipocytes; Adrenergic beta-Agonists; Adult; Body Mass Index; Bucladesine; Clonidine; Colforsin; Dia | 1996 |
In vivo increase in beta-adrenergic lipolytic response in subcutaneous adipose tissue of obese subjects submitted to a hypocaloric diet.
Topics: Adipose Tissue; Adrenergic beta-Agonists; Adult; Diet, Reducing; Dobutamine; Energy Intake; Female; | 1997 |
Transgenic mice overexpressing the beta 1-adrenergic receptor in adipose tissue are resistant to obesity.
Topics: Adenylyl Cyclases; Adipose Tissue; Adipose Tissue, Brown; Adrenergic beta-1 Receptor Agonists; Adren | 1997 |
Adipose tissue lipolysis and hormone-sensitive lipase expression during very-low-calorie diet in obese female identical twins.
Topics: Adipose Tissue; Adrenergic Agents; Adrenergic beta-Agonists; Adult; Diet, Reducing; Energy Intake; E | 1997 |
Leptin impairs metabolic actions of insulin in isolated rat adipocytes.
Topics: Adipocytes; Adipose Tissue; Animals; Biological Transport; Cells, Cultured; Cloning, Molecular; Cycl | 1997 |
Lipolytic catecholamine resistance linked to alpha 2-adrenoceptor sensitivity--a metabolic predictor of weight loss in obese subjects.
Topics: Adenosine Deaminase; Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adult; Bio | 1997 |
Cellular insulin resistance in adipocytes from obese polycystic ovary syndrome subjects involves adenosine modulation of insulin sensitivity.
Topics: Adenosine; Adipocytes; Adrenergic beta-Agonists; Adult; Female; Follicle Stimulating Hormone; Glucos | 1997 |
Decreased white fat cell thermogenesis in obese individuals.
Topics: Adipocytes; Body Temperature Regulation; Calorimetry; Cells, Cultured; Fatty Acids, Nonesterified; F | 1997 |
Angiotensinogen gene expression in adipose tissue: analysis of obese models and hormonal and nutritional control.
Topics: 3T3 Cells; Adipocytes; Adipose Tissue; Adrenergic beta-Agonists; Adult; Analysis of Variance; Angiot | 1997 |
More marked stimulation by lithium than insulin of the glycogenic pathway in rat skeletal muscle.
Topics: Androstadienes; Animals; Biological Transport; Cytochalasin B; Dantrolene; Deoxyglucose; Glucose; Gl | 1997 |
Noradrenaline-induced lipolysis in isolated mesenteric, omental and subcutaneous adipocytes from obese subjects.
Topics: Adipocytes; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adult; Dobutamine; Dose-Response Re | 1997 |
In vitro lipolytic effect of leptin on mouse adipocytes: evidence for a possible autocrine/paracrine role of leptin.
Topics: Adipocytes; Animals; Carrier Proteins; Dobutamine; Epinephrine; Female; Glycerol; In Vitro Technique | 1997 |
Reduced cardiac contractile responsiveness to isoproterenol in obese rabbits.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Isoprotereno | 1997 |
Composition of dietary fat affects blood pressure and insulin responses to dietary obesity in the dog.
Topics: Adrenergic beta-Agonists; Animals; Blood Glucose; Blood Pressure; Body Composition; Chlorisondamine; | 1998 |
An exploratory investigation of the morphology and biochemistry of cellulite.
Topics: Abdomen; Adipose Tissue; Adrenergic beta-Agonists; Adult; Biopsy; Ethanol; Female; Humans; Isoproter | 1998 |
Hormone-sensitive lipase expression and activity in relation to lipolysis in human fat cells.
Topics: Adipocytes; Adult; Cell Size; Female; Genetic Variation; Humans; Immunochemistry; In Vitro Technique | 1998 |
The putative role of the hormone-sensitive lipase gene in the pathogenesis of Type II diabetes mellitus and abdominal obesity.
Topics: Abdomen; Adipose Tissue; Adrenergic beta-Agonists; Aged; Alleles; Body Constitution; Diabetes Mellit | 1998 |
Is visceral adiposity a significant correlate of subcutaneous adipose cell lipolysis in men?
Topics: Abdomen; Adenosine Deaminase; Adipocytes; Adipose Tissue; Adrenergic beta-Agonists; Adult; Body Cons | 1999 |
Endurance training increases the beta-adrenergic lipolytic response in subcutaneous adipose tissue in obese subjects.
Topics: Adipose Tissue; Adrenergic beta-Agonists; Adult; Exercise; Fatty Acids, Nonesterified; Glucose Toler | 1999 |
Substrate utilization and thermogenic responses to beta-adrenergic stimulation in obese subjects with NIDDM.
Topics: Adrenergic beta-Agonists; Blood Glucose; Body Composition; Body Temperature Regulation; Diabetes Mel | 1999 |
Regional and gender variations in adipose tissue lipolysis in response to weight loss.
Topics: Adenosine Deaminase; Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adult; Dob | 1999 |
Microdialysis assessment of local adipose tissue lipolysis during beta-adrenergic stimulation in upper-body-obese subjects with type II diabetes.
Topics: Adipose Tissue; Adrenergic beta-Agonists; Blood Glucose; Diabetes Mellitus, Type 2; Energy Metabolis | 1999 |
Hormonal control of plasminogen activator inhibitor-1 gene expression and production in human adipose tissue: stimulation by glucocorticoids and inhibition by catecholamines.
Topics: Adipose Tissue; Adrenergic beta-Agonists; Catecholamines; Cyclic AMP; Dexamethasone; Dose-Response R | 1999 |
Chronic infusion of norepinephrine into the VMH of normal rats induces the obese glucose-intolerant state.
Topics: Adipose Tissue; Animals; Carbohydrate Metabolism; Endocrine Glands; Female; Glucose Intolerance; Hor | 2000 |
Influence of heredity for obesity on adipocyte lipolysis in lean and obese subjects.
Topics: Adipocytes; Adult; Blood Glucose; Blood Pressure; Body Mass Index; Bucladesine; Cholesterol, HDL; Co | 2000 |
beta-adrenoceptor-stimulated lipolysis of subcutaneous abdominal adipocytes as a determinant of fat oxidation in obese men.
Topics: Abdomen; Adipocytes; Adipose Tissue; Adrenergic beta-Agonists; Adult; Bucladesine; Cells, Cultured; | 2000 |
Effects of growth hormone treatment in obese prepubertal boys.
Topics: Adipocytes; Adipose Tissue; Blood Glucose; Body Composition; Child; Glucose Tolerance Test; Homeosta | 2000 |
No difference in the lipolytic response to beta-adrenoceptor stimulation in situ but a delayed increase in adipose tissue blood flow in moderately obese compared with lean men in the postexercise period.
Topics: Adipose Tissue; Adult; Exercise; Fatty Acids, Nonesterified; Glycerol; Heart Rate; Humans; Hydralazi | 2000 |
[Hemodynamic consequences of endogenous hyperinsulinism in obese rats with lesions of the ventromedial hypothalamus].
Topics: Adrenergic Agonists; Adrenergic beta-Agonists; Animals; Atropine; Baroreflex; Blood Pressure; Bradyc | 2000 |
In situ metabolic and hemodynamic response to dexfenfluramine in white adipose tissue of rats.
Topics: Adipose Tissue; Adrenergic beta-Agonists; Animals; Dexfenfluramine; Glycolysis; Isoproterenol; Lacti | 2001 |
The lipid-mobilizing effect of atrial natriuretic peptide is unrelated to sympathetic nervous system activation or obesity in young men.
Topics: Adipocytes; Adrenergic beta-Antagonists; Adult; Analysis of Variance; Atrial Natriuretic Factor; Bio | 2001 |
Vascular insulin/insulin-like growth factor-1 resistance in female obese Zucker rats.
Topics: Animals; Aorta; Cholera Toxin; Deoxyglucose; Drug Resistance; Endothelium, Vascular; Female; GTP-Bin | 2001 |
The effects of insulin and beta-adrenergic stimulation on glucose transport, glut 4 and PKB activation in the myocardium of lean and obese non-insulin dependent diabetes mellitus rats.
Topics: Adrenergic beta-Agonists; Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mell | 2001 |
Impaired beta-adrenergic signaling pathway in white adipocytes of suckling fa/fa Zucker rats: a defect in receptor coupling.
Topics: Adenylyl Cyclases; Adipocytes; Animals; Animals, Newborn; Blotting, Western; Catecholamines; Colfors | 2001 |
Increased lipolysis in adipose tissue and lipid mobilization to natriuretic peptides during low-calorie diet in obese women.
Topics: Adipocytes; Adipose Tissue; Adult; Cyclic GMP; Diet, Reducing; Female; Humans; Infusions, Intravenou | 2002 |
Effects of alpha- and beta-adrenergic stimulation on free magnesium concentrations in platelets from healthy and obese individuals.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adult; Blood Platelets; Clonidine; Epinephrine; | 2001 |
beta-Adrenoceptor density and adenylyl cyclase activity in obese rabbit hearts.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Blood Pressure; Female; Heart; Heart Rate; Hea | 2002 |
Catechol effect on the lysosomal enzymes in the adipose tissues of obese and obese-diabetic monkeys.
Topics: Acetylglucosaminidase; Adipose Tissue; Animals; beta-Galactosidase; Diabetes Mellitus; Glycoside Hyd | 1979 |
Effect of experimental diabetes, food deprivation and genetic obesity on the sensitivity of pithed rats to autonomic agents.
Topics: Acetylcholine; Animals; Autonomic Agents; Blood Glucose; Diabetes Mellitus, Experimental; Fatty Acid | 1976 |
The control of fatty acid metabolism in adult diabetes.
Topics: Adipose Tissue; Adult; Cyclic AMP; Diabetes Mellitus; Drug Synergism; Epinephrine; Fatty Acids; Glyc | 1975 |
Catecholamine receptor sensitivity and the regulation of lipolysis in adult diabetes.
Topics: Adipose Tissue; Cyclic AMP; Diabetes Mellitus; Epinephrine; Fatty Acids; Humans; Insulin; Isoprotere | 1976 |
Metabolism of mono- and diacylglycerols in subcutaneous adipose tissue of obese and normal-weight subjects.
Topics: Adipose Tissue; Adult; Aged; Cyclic AMP; Fatty Acids, Nonesterified; Female; Glycerol; Humans; Isopr | 1976 |
Spontaneous and experimental human obesity: effects of diet and adipose cell size on lipolysis and lipogenesis.
Topics: Adipose Tissue; Adult; Bucladesine; Diet; Female; Glycerol; Humans; Isoproterenol; Lipid Metabolism; | 1977 |
Influence of genetic obesity in mice on the lipolytic response of isolated adipocytes to isoproterenol and ACTH-(1-24).
Topics: Adipose Tissue; Adrenocorticotropic Hormone; Animals; Cell Count; Glucagon; Glycerol; Isoproterenol; | 1978 |
Relationship between lipolysis and calcium in epididymal adipose tissue of obese-hyperglycaemic mice.
Topics: Adenosine Triphosphate; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Bucladesine; Calcium; | 1979 |
Free fatty acid release from human adipose tissue in relation to obesity -- effect of isoprenaline.
Topics: Adipose Tissue; Body Weight; Fatty Acids, Nonesterified; Humans; Isoproterenol; Lipid Mobilization; | 1979 |
[Fatty acid release from human adipose tissue in relation to obesity - effect of isoprenaline (author's transl)].
Topics: Abdomen; Adipose Tissue; Adult; Fatty Acids; Female; Glycerol; Humans; Isoproterenol; Male; Middle A | 1977 |
Adipose tissue lipolysis after long-term overfeeding in identical twins.
Topics: Abdomen; Adipose Tissue; Adult; Epinephrine; Exercise; Humans; Hyperphagia; Isoproterenol; Life Styl | 1992 |
Regulation of cardiac adenylate cyclase activity in rodent models of obesity.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Binding, Competitive; Disease Models, Animal; | 1992 |
Somatostatin and growth hormone-releasing factor release from Zucker rat hypothalamic tissue.
Topics: Aging; Animals; Growth Hormone-Releasing Hormone; Hypothalamus, Middle; In Vitro Techniques; Iodine | 1992 |
Alterations in G-protein expression, Gi function and stimulatory receptor-mediated regulation of adipocyte adenylyl cyclase in a model of insulin-resistant diabetes with obesity.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Cell Membrane; Cells, Cultured; Colforsin; Diabetes Mell | 1992 |
Modulation by protein kinase C of the hormonal responsiveness of hepatocytes from lean (Fa/fa?) and obese (fa/fa) Zucker rats.
Topics: Animals; Enzyme Activation; Insulin Resistance; Isoenzymes; Isoproterenol; Liver; Obesity; Phenyleph | 1992 |
Regional differences in adrenoreceptor status of adipose tissue in adults and prepubertal children.
Topics: Adipose Tissue; Adult; Aging; Analysis of Variance; Child; Female; Humans; In Vitro Techniques; Isop | 1991 |
Attenuated adenosine-sensitivity and decreased adenosine-receptor number in adipocyte plasma membranes in human obesity.
Topics: Adenosine; Adenylyl Cyclases; Adipose Tissue; Body Weight; Cell Membrane; Colforsin; Cyclic AMP; Enz | 1991 |
Regional variation in adipose tissue lipolysis in lean and obese men.
Topics: Adipose Tissue; Adult; Body Composition; Clonidine; Epinephrine; Humans; Isoproterenol; Lipolysis; M | 1991 |
Alterations in G-protein expression and the hormonal regulation of adenylate cyclase in the adipocytes of obese (fa/fa) Zucker rats.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Cell Membrane; Cells, Cultured; Glucagon; GTP-Binding Pr | 1991 |
Winner of the 1988 NAASO Young Investigator Award. Regulation of fat cell adenylate cyclase in young Zucker (fa/fa) rats: alterations in GTP sensitivity of adenosine A1 mediated inhibition.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adipose Tissue; Animals; Awards and Prize | 1990 |
Abdominal fat cell lipolysis, body fat distribution, and metabolic variables in premenopausal women.
Topics: Abdominal Muscles; Adipose Tissue; Adult; Epinephrine; Fasting; Female; Humans; Insulin; Isoproteren | 1990 |
Alterations in beta-adrenergic sensitivity and platelet alpha 2-adrenoceptors in obese women: effect of exercise and caloric restriction.
Topics: Adult; Blood Platelets; Energy Intake; Female; Heart Rate; Humans; Isoproterenol; Middle Aged; Norep | 1990 |
Regional changes in adrenergic receptor status during hypocaloric intake do not predict changes in adipocyte size or body shape.
Topics: Abdomen; Adipose Tissue; Adult; Anthropometry; Biopsy, Needle; Body Mass Index; Buttocks; Clonidine; | 1990 |
Renovascular beta adrenergic hypersensitivity and hyperinsulinemia in rats with dietary-induced obesity.
Topics: Angiotensins; Animals; Blood Pressure; Dietary Fats; Hypertension; Insulin; Isoproterenol; Male; Obe | 1990 |
Nonreceptor-mediated responses of adenylate cyclase in membranes from liver, muscle, and white and brown adipose tissue of obese (fa/fa) and lean (Fa/) Zucker rats.
Topics: Adenylyl Cyclases; Adipose Tissue; Adipose Tissue, Brown; Animals; Body Weight; Colforsin; Cyclic AM | 1990 |
Metabolism of adipose tissue in intraabdominal depots in severely obese men and women.
Topics: Abdomen; Adipose Tissue; Adult; Fatty Acids, Nonesterified; Female; Humans; Isoproterenol; Lipolysis | 1990 |
Lipolysis in isolated epididymal adipocytes from genetically obese Zucker rat treated with 3,5,3'-L-triiodothyronine.
Topics: Adipose Tissue; Animals; Epididymis; Epinephrine; Glycerol; Isoproterenol; Lipolysis; Male; Obesity; | 1990 |
Evidence for abnormal prostaglandin synthesis in obese Zucker rat adipose cell cultures.
Topics: Adenosine Deaminase; Adipose Tissue; Animals; Bucladesine; Cell Differentiation; Cells, Cultured; Di | 1989 |
Lipid mobilization by obese and lean pigs infused with the beta-adrenergic agonist isoproterenol.
Topics: Animals; Food Deprivation; Infusions, Intravenous; Isoproterenol; Lipid Mobilization; Male; Obesity; | 1989 |
Adrenergic regulation of lipolysis in abdominal adipocytes of obese subjects during caloric restriction: reversal of catecholamine action caused by relief of endogenous inhibition.
Topics: Adenosine; Adipose Tissue; Adolescent; Adrenergic Agonists; Adult; Aged; Catecholamines; Cells, Cult | 1985 |
Glutamine metabolism in isolated incubated adipocytes of the rat.
Topics: Adipose Tissue; Alanine; Ammonia; Animals; Glucose; Glutamates; Glutamic Acid; Glutaminase; Glutamin | 1988 |
Alterations in membrane function, organization and composition in the obese ob/ob mouse.
Topics: 5'-Nucleotidase; Adipose Tissue; Animals; Calcium; Cell Membrane; Cyclic AMP; Fluorescence Polarizat | 1985 |
Attenuated adenosine R-site effect in adipocytes in obesity.
Topics: Adenosine; Adipose Tissue; Body Weight; Cyclic AMP; Humans; Isoproterenol; Lipolysis; Obesity; Pheny | 1986 |
Visceral obesity and diabetes.
Topics: Adipose Tissue; Adult; Anthropometry; Blood Glucose; Diabetes Mellitus; Female; Glucose Tolerance Te | 1988 |
[Reduced sensitivity of the heart ventricle of obese Zucker rats to isoprenaline].
Topics: Action Potentials; Animals; Heart; Heart Ventricles; Isoproterenol; Myocardial Contraction; Obesity; | 1988 |
Effect of the genetic background and specific mutation on adenylate cyclase activity in obesity syndromes.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Cell Membrane; Diabetes Mellitus, Experimental; Enzyme A | 1988 |
The regulation of adenylate cyclase in liver membranes of lean and obese mice.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Enzyme Activation | 1988 |
Relationship of islet function to insulin action in human obesity.
Topics: Adult; Arginine; Blood Glucose; Female; Humans; Insulin; Insulin Resistance; Islets of Langerhans; I | 1987 |
Antilipolytic action of insulin in abdominal adipocytes of obese subjects before and during energy restriction. Influence of adenosine deaminase.
Topics: Abdomen; Adenosine Deaminase; Adipose Tissue; Adult; Clonidine; Dinoprostone; Dose-Response Relation | 1987 |
Site- and sex-related differences in adrenoreceptor status of human adipose tissue.
Topics: Abdomen; Adipose Tissue; Body Height; Body Weight; Buttocks; Female; Humans; Isoproterenol; Male; No | 1987 |
Antilipolytic effects of N6-phenylisopropyladenosine and prostaglandin E2 in fat-cells of obese volunteers before and during energy restriction.
Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Adult; Dinoprostone; Female; Glycerol; Humans; In Vi | 1985 |
No inotropic action of enkephalins or enkephalin derivatives on electrically-stimulated atria isolated from lean and obese rats.
Topics: Animals; Atrial Function; Carbachol; Electric Stimulation; Enkephalin, Leucine; Enkephalin, Leucine- | 1985 |
An analysis of the lipolysis in vitro of obese-hyperglycaemic and diabetic mice.
Topics: Adenine Nucleotides; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Blood Glucose; Cyclic AMP | 1969 |
Lipolysis and adenosine 3',5'-cyclic monophosphate in adipose tissue of the New Zealand obese mouse.
Topics: Adipose Tissue; Age Factors; Animals; Body Weight; Cyclic AMP; Glycerol; Isoproterenol; Lipid Metabo | 1973 |
Triglyceride storage disease: a disorder of lipolysis in adipose tissue in two patients.
Topics: Adipose Tissue; Adult; Biopsy; Cyclic AMP; Fasting; Fatty Acids; Female; Glycerol; Humans; In Vitro | 1973 |
Insulin-receptor interaction in the obese-hyperglycemic mouse. A model of insulin resistance.
Topics: Animals; Cell Fractionation; Cell Membrane; Electrophoresis, Disc; Genetics; Glucagon; Growth Hormon | 1973 |
[Six years' experience with a musculoplastic technic].
Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists | 1971 |
Cyclic adenosine monophosphate in human adipose tissue.
Topics: Acetanilides; Adenylyl Cyclases; Adipose Tissue; Adrenal Glands; Adrenergic beta-Antagonists; Amino | 1972 |
Studies of immunoreactive insulin secretion in NZO mice in vivo.
Topics: Aminophylline; Animals; Antigens; Arginine; Diabetes Mellitus; Disease Models, Animal; Fasting; Gluc | 1974 |
Cardiotoxicity of isoproterenol in experimental animals. Influence of stress, obesity, and repeated dosing.
Topics: Animals; Dietary Carbohydrates; Dietary Fats; Dogs; Dose-Response Relationship, Drug; Heart; Heart D | 1972 |
The glucose receptor. A defective mechanism in diabetes mellitus distinct from the beta adrenergic receptor.
Topics: Blood Glucose; Diabetes Mellitus; Glucose; Humans; Insulin; Isoproterenol; Obesity; Propranolol; Rec | 1973 |
Life-threatening asthma.
Topics: Acid-Base Equilibrium; Age Factors; Aged; Anti-Bacterial Agents; Asthma; Blood Gas Analysis; Broncho | 1968 |