Compounds > isoproterenol
Page last updated: 2024-10-29

isoproterenol and Necrosis

isoproterenol has been researched along with Necrosis in 333 studies

Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"The current study enumerates the beneficial role of sciadopitysin (SDN) against isoproternol (ISO)-induced myocardial infarction (MI) in rats."7.96Protective Effect of Sciadopitysin against Isoproternol-Induced Myocardial Infarction in Rats. ( Cai, Y; Li, Y, 2020)
"Isoproterenol (ISO) induced oxidative stress and inflammation is involved in the pathogenesis of myocardial necrosis."7.96Erdosteine salvages cardiac necrosis: Novel effect through modulation of MAPK and Nrf-2/HO-1 pathway. ( Arya, DS; Bhatia, J; Malik, S; Mutneja, E; Ray, R; Sahu, AK; Verma, VK, 2020)
"The aim of the current study was to investigate the protective role of wild garlic or TVL on isoproterenol (ISO)-induced myocardial necrosis in rats."7.91Protective role of wild garlic on isoproterenol-induced myocardial necrosis in wistar rats. ( Mackraj, I; Moodley, K; Murugesan, S; Pandiyan, A; Saravanakumar, L, 2019)
" The present study was intended to appraise the nutraceutical inherent of HPLC standardized Spinacia oleracea methanolic leaf extract (SoLE) in isoproterenol (ISO) induced male albino Wistar rats via activation of pro-inflammatory signaling pathway that drives myocardial necrosis."7.85Nutraceutical inherent of Spinacia oleracea Linn. methanolic leaf extract ameliorates isoproterenol induced myocardial necrosis in male albino Wistar rats via mitigating inflammation. ( Jolapuram, U; Kodidhela, LD; Vutharadhi, S, 2017)
"This study aimed to evaluate the antithrombotic, anti-inflammatory and anti-cardiac remodeling properties of eugenol in isoproterenol-induced myocardial infarction in rats."7.83Anti-inflammatory, Antithrombotic and Cardiac Remodeling Preventive Effects of Eugenol in Isoproterenol-Induced Myocardial Infarction in Wistar Rat. ( Allouche, N; Derbali, F; Ellefi, H; Gammoudi, A; Gharsallah, N; Hajji, R; Kadri, A; Khabbabi, G; Mnafgui, K, 2016)
"Combined effects of vincristine and quercetin in the regulation of isoproterenol (ISO)-induced cardiac necrosis have been evaluated in rats."7.81Combined Effects of Vincristine and Quercetin in Reducing Isoproterenol-Induced Cardiac Necrosis in Rats. ( Kar, A; Panda, S, 2015)
"This study investigated the protective effect of vincristine (VCR) on isoproterenol (ISO)-induced cardiac necrosis (CN) in rats."7.80Cardioprotective effect of vincristine on isoproterenol-induced myocardial necrosis in rats. ( Kar, A; Panda, S; Ramamurthy, V, 2014)
"Our study concluded that ritonavir, a nonspecific GLUT inhibitors showed complete protection in catecholamine induced myocardial necrosis."7.79Cardioprotective effect of ritonavir, an antiviral drug, in isoproterenol induced myocardial necrosis: a new therapeutic implication. ( Banerjee, SK; Bulani, Y; Gupta, P; Kanwal, A; Khatua, TN; Kuncha, M; Putcha, UK; Sojitra, B, 2013)
" In the present study, we evaluated the effects of metformin on cardiac function, hemodynamic parameters, and histopathological changes in isoproterenol-induced myocardial infarction (MI)."7.78Acute treatment with metformin improves cardiac function following isoproterenol induced myocardial infarction in rats. ( Garjani, A; Khorrami, A; Maleki-Dizaji, N; Soraya, H, 2012)
" Roxb (SR) extract on heart weight, plasma lipid profile, plasma marker enzymes, lipid peroxidation, endogenous enzymatic and non-enzymatic antioxidants and membrane bound ATPases against isoproterenol (IP) induced myocardial necrosis (MN) in rats."7.77Cardioprotective effect of Sida rhomboidea. Roxb extract against isoproterenol induced myocardial necrosis in rats. ( Devkar, RV; Jadeja, RN; Karn, SS; Padate, GS; Patel, DK; Ramachandran, AV; Salunke, SP; Shah, JD; Thounaojam, MC, 2011)
"The present study was designed to investigate whether Khamira Abresham Hakim Arshad Wala (KAHAW), a preparation of Unani System of Medicine, is able to attenuate the isoproterenol (ISO)-induced myocardial necrosis on the basis of its effects on hemodynamic, antioxidant, histopathological and ultrastructural parameters."7.76Cardioprotective effect of 'Khamira Abresham Hakim Arshad Wala' a unani formulation in isoproterenol-induced myocardial necrosis in rats. ( Arora, S; Arya, DS; Goyal, S; Joshi, S; Mittal, R; Siddiqui, KM; Siddiqui, MK, 2010)
") juice (PJ) on heart weight, infarct size, plasma marker enzymes of cardiac damage, lipid peroxidation, endogenous enzymatic and non-enzymatic antioxidants, cardiac ATPases and histopathology of isoproterenol (IP)-induced cardiac necrosis (CN) in rats."7.76Pomegranate (Punica granatum L.) juice supplementation attenuates isoproterenol-induced cardiac necrosis in rats. ( Devkar, RV; Jadeja, RN; Patel, DK; Ramachandran, AV; Thounaojam, MC, 2010)
"In our investigation,we used short-time model of myocardial infarction of rats induced by high dose of isoproterenol (ISP)."7.74Troponin T and histological characteristics of rat myocardial infarction induced by isoproterenol. ( Hasić, S; Jadrić, R; Kiseljaković, E; Mornjaković, Z; Winterhalter-Jadrić, M, 2007)
"In the present study, chronic treatment of atorvastatin was evaluated on isoproterenol-induced myocardial infarction."7.73Effect of atorvastatin treatment on isoproterenol-induced myocardial infarction in rats. ( Balaraman, R; Bothara, SB; Majithiya, JB; Trivedi, CJ, 2006)
" Cardiac lesions induced by isoproterenol (ISO) are characterized by myocardial necrosis and exudative infiltration."7.72Effect of D-003 on isoproterenol-induced myocardial necrosis in rats. ( Arruzazabala, ML; Carbajal, D; González, J; Más, R; Mendoza, S; Molina, V; Noa, M, 2003)
"Arjunolic acid, a new triterpene and a potent principle from the bark of Terminalia arjuna, has been shown to provide significant cardiac protection in isoproterenol induced myocardial necrosis in rats."7.71Experimental myocardial necrosis in rats: role of arjunolic acid on platelet aggregation, coagulation and antioxidant status. ( Arutselvan, N; Balakrishna, K; Kumar, DA; Manikandan, P; Manohar, BM; Puvanakrishnan, R; Sumitra, M, 2001)
"Myocardial infarction (MI) was produced in rats with 85, 200 and 300 mg/kg of isoproterenol (ISO) administered subcutaneously (sc) twice at an interval of 24 h."7.71Cardioprotective potential of ocimum sanctum in isoproterenol induced myocardial infarction in rats. ( Arya, DS; Gupta, SK; Joshi, S; Kishore, K; Sharma, M, 2001)
"A novel tetrapeptide derivative Boc-Lys(Boc)-Arg-Asp-Ser(tbu)-OtBu (PEP1261) has been tested in vivo in isoproterenol (ISO) hydrochloride (HCl)-induced myocardial necrosis in rats."7.71Antioxidant potential of a novel tetrapeptide derivative in isoproterenol-induced myocardial necrosis in rats. ( Arutselvan, N; Gayathri, C; Kumar, DA; Manikandan, P; Manohar, BM; Puvanakrishnan, R; Sumitra, M, 2002)
"This study demonstrates that isoproterenol-induced myocardial necrosis resulted in progressive hemodynamic dysfunction of the left ventricle which most closely correlated with alterations in LV geometry."7.70Effect of left ventricular sphericity on the evolution of ventricular dysfunction in rats with diffuse isoproterenol-induced myocardial necrosis. ( Pfeffer, JM; Pfeffer, MA; Teerlink, JR, 1998)
"Isoproterenol hydrochloride (ISO), a beta adrenergic agonist, is known to cause ischemic necrosis in rats."7.70Effect of a novel tetrapeptide derivative in a model of isoproterenol induced myocardial necrosis. ( Jayakumar, R; Jayasundar, S; Malarvannan, P; Puvanakrishnan, R; Ramesh, CV, 1998)
"This study was carried out to evaluate whether curcumin, a potent antioxidant, had any specific role in the synthesis and degradation of collagen in rat heart with myocardial necrosis, induced by isoproterenol."7.70Curcumin treatment modulates collagen metabolism in isoproterenol induced myocardial necrosis in rats. ( Anand, S; Nirmala, C; Puvanakrishnan, R, 1999)
"Treatment of rats with the beta-adrenergic agonist isoproterenol results in cardiac hypertrophy, myocyte necrosis, and interstitial cell fibrosis."7.67Isoproterenol-induced myocardial fibrosis in relation to myocyte necrosis. ( Benjamin, IJ; Cho, K; Clark, WA; Jalil, JE; Tan, LB; Weber, KT, 1989)
"Isoproterenol produces myocardial necrosis in rats."7.67Protection against isoproterenol-induced myocardial necrosis in rats by 6-mercaptopurine and 6-thioguanine or by irradiation. ( Balazs, T; Joseph, X, 1989)
"Administration of a single high dose or multiple low doses of isoproterenol (ISO) to rats induces myocardial necrosis and cardiac hypertrophy."7.67Quantification of myocardial necrosis and cardiac hypertrophy in isoproterenol-treated rats. ( Brinkman, CJ; Knufman, NM; van der Laarse, A; Vliegen, HW, 1987)
"Isoproterenol-induced myocardial necrosis was examined in male mice with alloxan-induced and genetically transmitted diabetes."7.67Influence of the diabetic state on isoproterenol-induced cardiac necrosis. ( el-Hage, AN; Ferrans, VJ; Herman, EH; Jordan, AW, 1985)
"The new calcium antagonist anipamil (1,7-bis-(3-methoxyphenyl)-3-methylaza-7-cyano-nonadecane) exhibited a pronounced protective effect against isoprenaline-induced myocardial necrosis in rats."7.67Protective effect of the new calcium antagonist anipamil against isoprenaline-induced cardionecrosis in rats. ( Ciplea, AG; Heimann, W; Kirchengast, M; Kretzschmar, R; Safer, A, 1988)
"Large doses of isoproterenol, which produced macroscopically visible myocardial necrosis, induced the synthesis and accumulation of a 71,000 dalton protein (SP71) in the heart, aorta, and salivary gland of adult male rats."7.67Isoproterenol induced myocardial necrosis is associated with stress protein synthesis in rat heart and thoracic aorta. ( White, FP; White, SR, 1986)
"Prophylactic effects of sulfinpyrazone (100 mg/Kg), aspirin (5 mg/Kg, 50 mg/Kg), and propranolol (2 mg/Kg, 10 mg/Kg) on myocardial necrosis and hypertrophy induced by isoproterenol were examined."7.66Effects of sulfinpyrazone, aspirin and propranolol on the isoproterenol-induced myocardial necrosis. ( Hashimoto, H; Ogawa, K, 1981)
"Myocardial necrosis was induced in male Wistar rats by isoproterenol as described by Rona et al."7.66Hypoxic tolerance of rats with isoproterenol-induced myocardial necrosis. ( Bhatia, B; Datta, K; Nijhawan, R, 1980)
"Changes in myocardial zinc level was followed up over a period of 5 days after producing myocardial necrosis in albino rats by subcutaneous injection of isoproterenol, 85 mg/kg body weight."7.66A temporal profile of myocardial zinc changes after isoproterenol induced cardiac necrosis. ( Ahmad, MS; Hasan, MZ; Jamil, SA; Kumar, S; Mathew, BM; Seth, TD, 1978)
"Male and female, arteriosclerotic and non-arteriosclerotic rats were treated with the anti-lipemic agent, clofibrate, for 8 days and then subjected to an acute myocardial infarction by injecting them with two large doses of isoproterenol spaced 24 hours apart."7.66Protective effects of clofibrate on isoproterenol-induced myocardial infarction in arteriosclerotic and non-arteriosclerotic rats. ( Greenberg, BP; Wexler, BC, 1978)
"The changes in myocardial copper were studied over a period of five days after producing myocardial necrosis in albino rats by subcutaneous injection of isoproterenol."7.66A temporal profile of changes in myocardial copper after isoproterenol induced cardiac necrosis. ( Ahmad, M; Jamil, SA; Kumar, S; Mahdi, SQ; Mathew, BM; Seth, TD, 1978)
"Trapidil increases the isoprenalin-induced necrosis of the myocardium in the rat."7.65[Modification of the isoprenaline-induced myocardial necrosis using trapidil]. ( Lampe, D; Lange, B; Mai, I, 1976)
"Isoproterenol (ISO), a drug which causes an increased strength of myocardial contraction when administered to animals in mug/kg doses, causes myocardial necrosis when given mg/kg doses."7.65Calcium as mediator of isoproterenol-induced myocardial necrosis. ( Bloom, S; Davis, DL, 1972)
"Heart failure is a disease predominantly caused by an energy metabolic disorder in cardiomyocytes."5.42Modulation of fatty acid metabolism is involved in the alleviation of isoproterenol-induced rat heart failure by fenofibrate. ( Cheng, X; Li, P; Luo, S; Pan, C, 2015)
"Myocardial infarction was produced in rats with 65, 85, 120 and 200mg/kg of ISO administered subcutaneously (sc) twice at an interval of 24h."5.35Cardioprotective activity of Ginkgo biloba Phytosomes in isoproterenol-induced myocardial necrosis in rats: a biochemical and histoarchitectural evaluation. ( Naik, SR; Panda, VS, 2008)
"Isoproterenol caused an increase in myocardial oxidative stress in control rats, as evidenced by an increase in myocardial TBARS level, reduction in FRAP and myocardial SOD, catalase and GPx activity, along with focal necrosis of cardiac muscle fibres on light microscopy."5.33Dietary palm olein oil augments cardiac antioxidant enzymes and protects against isoproterenol-induced myocardial necrosis in rats. ( Dinda, AK; Maulik, SK; Narang, D; Sood, S; Thomas, M, 2005)
"When celiprolol was administered half an hour before isoprenaline, the extent of necrosis caused by catecholamine was reduced."5.28[Effect of celiprolol on isoprenaline-induced myocardial necrosis]. ( Bednarík, B; Cerný, E; Foukal, T; Lupínek, Z; Mitova, M, 1990)
"The necrosis was confirmed by ECG changes, increased serum activities of AspAT, AlAT, GPT and LDH, and by histological examination."5.26A temporal profile of changes in myocardial manganese after isoprenaline induced cardiac necrosis in albino rats. ( Ahmad, M; Hasan, MZ; Jameel, SA; Kumar, S; Mathew, BM; Seth, TD, 1979)
"Propranolol pretreatment decreased the accumulation of radioactivity in a dose-dependent fashion."5.26Quantitation of isoproterenol-induced myocardial necrosis with 3H-tetracycline. ( Athari-Nejad, A; Holcslaw, TL; Ryan, CF, 1979)
" These studies disclosed the unique nature of isoproterenol in producing 'infarct-like' myocardial necrosis."4.77Catecholamine cardiotoxicity. ( Rona, G, 1985)
"The current study enumerates the beneficial role of sciadopitysin (SDN) against isoproternol (ISO)-induced myocardial infarction (MI) in rats."3.96Protective Effect of Sciadopitysin against Isoproternol-Induced Myocardial Infarction in Rats. ( Cai, Y; Li, Y, 2020)
"Isoproterenol (ISO) induced oxidative stress and inflammation is involved in the pathogenesis of myocardial necrosis."3.96Erdosteine salvages cardiac necrosis: Novel effect through modulation of MAPK and Nrf-2/HO-1 pathway. ( Arya, DS; Bhatia, J; Malik, S; Mutneja, E; Ray, R; Sahu, AK; Verma, VK, 2020)
" The present study was intended to appraise the nutraceutical inherent of HPLC standardized Spinacia oleracea methanolic leaf extract (SoLE) in isoproterenol (ISO) induced male albino Wistar rats via activation of pro-inflammatory signaling pathway that drives myocardial necrosis."3.85Nutraceutical inherent of Spinacia oleracea Linn. methanolic leaf extract ameliorates isoproterenol induced myocardial necrosis in male albino Wistar rats via mitigating inflammation. ( Jolapuram, U; Kodidhela, LD; Vutharadhi, S, 2017)
" The current study evaluated the consequence of AP in isoproterenol (ISO)-induced oxidative stress and myocardial infarction during β-adrenergic receptor stimulus in rats by persistent hemodynamic, biochemical and histopathological changes."3.83Apigenin Attenuates β-Receptor-Stimulated Myocardial Injury Via Safeguarding Cardiac Functions and Escalation of Antioxidant Defence System. ( Buwa, CC; Goyal, SN; Mahajan, UB; Patil, CR, 2016)
"This study aimed to evaluate the antithrombotic, anti-inflammatory and anti-cardiac remodeling properties of eugenol in isoproterenol-induced myocardial infarction in rats."3.83Anti-inflammatory, Antithrombotic and Cardiac Remodeling Preventive Effects of Eugenol in Isoproterenol-Induced Myocardial Infarction in Wistar Rat. ( Allouche, N; Derbali, F; Ellefi, H; Gammoudi, A; Gharsallah, N; Hajji, R; Kadri, A; Khabbabi, G; Mnafgui, K, 2016)
"Combined effects of vincristine and quercetin in the regulation of isoproterenol (ISO)-induced cardiac necrosis have been evaluated in rats."3.81Combined Effects of Vincristine and Quercetin in Reducing Isoproterenol-Induced Cardiac Necrosis in Rats. ( Kar, A; Panda, S, 2015)
"Recent evidence has shown that, in heart failure (HF), clinically relevant concentrations of angiotensin-(1-7) [Ang-(1-7)] counteracts angiotensin II induced cardiac depression and produces positive inotropic effects in both left ventricle (LV) and myocytes."3.81Modulation of cardiac L-type Ca2+ current by angiotensin-(1-7): normal versus heart failure. ( Cheng, CP; Cheng, HJ; Ferrario, CM; Li, T; Zhou, P, 2015)
"The present study was carried out to evaluate the protective effect of different statins on isoproterenol (ISO) induced myocardial necrosis."3.81Comparative evaluation of HMG CoA reductase inhibitors in experimentally-induced myocardial necrosis: Biochemical, morphological and histological studies. ( Gandhi, HP; Patel, SS; Rathod, SP; Trivedi, JI; Variya, BC, 2015)
"Our study concluded that ritonavir, a nonspecific GLUT inhibitors showed complete protection in catecholamine induced myocardial necrosis."3.79Cardioprotective effect of ritonavir, an antiviral drug, in isoproterenol induced myocardial necrosis: a new therapeutic implication. ( Banerjee, SK; Bulani, Y; Gupta, P; Kanwal, A; Khatua, TN; Kuncha, M; Putcha, UK; Sojitra, B, 2013)
" In the present study, we evaluated the effects of metformin on cardiac function, hemodynamic parameters, and histopathological changes in isoproterenol-induced myocardial infarction (MI)."3.78Acute treatment with metformin improves cardiac function following isoproterenol induced myocardial infarction in rats. ( Garjani, A; Khorrami, A; Maleki-Dizaji, N; Soraya, H, 2012)
"Oral administration of matrine (200, 100 and 50 mg/kg) significantly attenuated isoproterenol-induced cardiac necrosis and left ventricular dysfunction."3.78Regulation of endothelial nitric oxide synthase and asymmetric dimethylarginine by matrine attenuates isoproterenol-induced acute myocardial injury in rats. ( Dai, G; Deng, N; Guo, Y; Li, X; Wang, X; Wu, Y; Xu, Q; Zheng, P, 2012)
"The present study was designed to investigate whether Khamira Abresham Hakim Arshad Wala (KAHAW), a preparation of Unani System of Medicine, is able to attenuate the isoproterenol (ISO)-induced myocardial necrosis on the basis of its effects on hemodynamic, antioxidant, histopathological and ultrastructural parameters."3.76Cardioprotective effect of 'Khamira Abresham Hakim Arshad Wala' a unani formulation in isoproterenol-induced myocardial necrosis in rats. ( Arora, S; Arya, DS; Goyal, S; Joshi, S; Mittal, R; Siddiqui, KM; Siddiqui, MK, 2010)
") juice (PJ) on heart weight, infarct size, plasma marker enzymes of cardiac damage, lipid peroxidation, endogenous enzymatic and non-enzymatic antioxidants, cardiac ATPases and histopathology of isoproterenol (IP)-induced cardiac necrosis (CN) in rats."3.76Pomegranate (Punica granatum L.) juice supplementation attenuates isoproterenol-induced cardiac necrosis in rats. ( Devkar, RV; Jadeja, RN; Patel, DK; Ramachandran, AV; Thounaojam, MC, 2010)
"This study investigates the cardioprotective activity of a combined treatment of Ginkgo biloba phytosomes (GBP) and Ocimum sanctum extract (Os) in isoproterenol (ISO)-induced myocardial necrosis in rats."3.75Evaluation of cardioprotective activity of Ginkgo biloba and Ocimum sanctum in rodents. ( N, SR; Panda, VS, 2009)
" The possible pharmacodynamic interaction between CCBs (verapamil, amlodipine and diltiazem) and BQ/BQT was studied on isoproterenol (ISO)-induced myocardial necrosis in mice."3.75Influence of betel quid on effect of calcium channel blockers on isoprenaline induced myocardial necrosis in mice. ( Asad, M; Asdaq, SM; Kumar, V, 2009)
"In our investigation,we used short-time model of myocardial infarction of rats induced by high dose of isoproterenol (ISP)."3.74Troponin T and histological characteristics of rat myocardial infarction induced by isoproterenol. ( Hasić, S; Jadrić, R; Kiseljaković, E; Mornjaković, Z; Winterhalter-Jadrić, M, 2007)
" Similarly, adult beta1KOmdx males were more prone to isoproterenol-induced heart failure and death compared with control groups."3.74Combined deficiency of dystrophin and beta1 integrin in the cardiac myocyte causes myocardial dysfunction, fibrosis and calcification. ( Chu, AL; Chun, J; Elsherif, L; Huang, MS; Kaufman, SJ; Li, RY; Mekany, MA; Ross, RS; Shai, SY; Yang, Y, 2008)
"In this study, we employed rat model of acute myocardial necrosis induced by isoproterenol (ISO) to study the possible roles of corin, the protease uniquely distributing in myocardium to convert pro-brain natriuretic peptide (proBNP) to BNP, and neutral endopeptidase (NEP), the major enzyme to degrade BNP, in changing the levels of BNP."3.73Changes in production and metabolism of brain natriuretic peptide in rats with myocardial necrosis. ( Cai, DY; Geng, B; Jiang, HF; Jiang, W; Pan, CS; Qi, YF; Tang, CS, 2005)
"These results indicate that (1) Both IPC and beta-PC elicit protection against apoptosis and necrosis, (2) activation of p38 MAPK is not a trigger of preconditioning against apoptosis and necrosis and (3) activation of p38 MAPK during reperfusion increases necrosis only if ischaemia is used to precondition hearts, but not with pharmacologic preconditioning with isoproterenol."3.73Inhibition of myocardial apoptosis by ischaemic and beta-adrenergic preconditioning is dependent on p38 MAPK. ( Hartley, S; Lochner, A; Marais, E; Moolman, JA; Van Wyk, J, 2006)
"In the present study, chronic treatment of atorvastatin was evaluated on isoproterenol-induced myocardial infarction."3.73Effect of atorvastatin treatment on isoproterenol-induced myocardial infarction in rats. ( Balaraman, R; Bothara, SB; Majithiya, JB; Trivedi, CJ, 2006)
" Cardiac lesions induced by isoproterenol (ISO) are characterized by myocardial necrosis and exudative infiltration."3.72Effect of D-003 on isoproterenol-induced myocardial necrosis in rats. ( Arruzazabala, ML; Carbajal, D; González, J; Más, R; Mendoza, S; Molina, V; Noa, M, 2003)
"Myocardial ischemia and necrosis were induced in rats by isoproterenol (2 mg."3.72[Cardioprotective effect and influence on NOS expression of Montelukast sodium in rats]. ( Chen, S; Jin, G; Men, Q; Shan, J; Xu, L; Zhang, M, 2003)
"Isoproterenol could induce myocardial necrosis and apoptosis, TXLC could alleviate the myocardial injury through preventing myocardial cell necrosis and apoptosis."3.71[Experimental study of protective effect of tongxinluo capsule on isoproterenol induced myocardial injury in rats]. ( Liu, L; Wang, JR; Zhao, MZ, 2001)
"Arjunolic acid, a new triterpene and a potent principle from the bark of Terminalia arjuna, has been shown to provide significant cardiac protection in isoproterenol induced myocardial necrosis in rats."3.71Experimental myocardial necrosis in rats: role of arjunolic acid on platelet aggregation, coagulation and antioxidant status. ( Arutselvan, N; Balakrishna, K; Kumar, DA; Manikandan, P; Manohar, BM; Puvanakrishnan, R; Sumitra, M, 2001)
"Myocardial infarction (MI) was produced in rats with 85, 200 and 300 mg/kg of isoproterenol (ISO) administered subcutaneously (sc) twice at an interval of 24 h."3.71Cardioprotective potential of ocimum sanctum in isoproterenol induced myocardial infarction in rats. ( Arya, DS; Gupta, SK; Joshi, S; Kishore, K; Sharma, M, 2001)
"This study demonstrates that isoproterenol-induced myocardial necrosis resulted in progressive hemodynamic dysfunction of the left ventricle which most closely correlated with alterations in LV geometry."3.70Effect of left ventricular sphericity on the evolution of ventricular dysfunction in rats with diffuse isoproterenol-induced myocardial necrosis. ( Pfeffer, JM; Pfeffer, MA; Teerlink, JR, 1998)
"Isoproterenol hydrochloride (ISO), a beta adrenergic agonist, is known to cause ischemic necrosis in rats."3.70Effect of a novel tetrapeptide derivative in a model of isoproterenol induced myocardial necrosis. ( Jayakumar, R; Jayasundar, S; Malarvannan, P; Puvanakrishnan, R; Ramesh, CV, 1998)
"This study was carried out to evaluate whether curcumin, a potent antioxidant, had any specific role in the synthesis and degradation of collagen in rat heart with myocardial necrosis, induced by isoproterenol."3.70Curcumin treatment modulates collagen metabolism in isoproterenol induced myocardial necrosis in rats. ( Anand, S; Nirmala, C; Puvanakrishnan, R, 1999)
"Hepatic necrosis produced by carbon tetrachloride (0."3.68Potentiation of carbon tetrachloride hepatotoxicity by phenylpropanolamine. ( Harbison, RD; James, RC; Roberts, SM; Seng, JE, 1991)
"Treatment of rats with the beta-adrenergic agonist isoproterenol results in cardiac hypertrophy, myocyte necrosis, and interstitial cell fibrosis."3.67Isoproterenol-induced myocardial fibrosis in relation to myocyte necrosis. ( Benjamin, IJ; Cho, K; Clark, WA; Jalil, JE; Tan, LB; Weber, KT, 1989)
"Isoproterenol produces myocardial necrosis in rats."3.67Protection against isoproterenol-induced myocardial necrosis in rats by 6-mercaptopurine and 6-thioguanine or by irradiation. ( Balazs, T; Joseph, X, 1989)
"Administration of a single high dose or multiple low doses of isoproterenol (ISO) to rats induces myocardial necrosis and cardiac hypertrophy."3.67Quantification of myocardial necrosis and cardiac hypertrophy in isoproterenol-treated rats. ( Brinkman, CJ; Knufman, NM; van der Laarse, A; Vliegen, HW, 1987)
"Isoproterenol-induced myocardial necrosis was examined in male mice with alloxan-induced and genetically transmitted diabetes."3.67Influence of the diabetic state on isoproterenol-induced cardiac necrosis. ( el-Hage, AN; Ferrans, VJ; Herman, EH; Jordan, AW, 1985)
"The new calcium antagonist anipamil (1,7-bis-(3-methoxyphenyl)-3-methylaza-7-cyano-nonadecane) exhibited a pronounced protective effect against isoprenaline-induced myocardial necrosis in rats."3.67Protective effect of the new calcium antagonist anipamil against isoprenaline-induced cardionecrosis in rats. ( Ciplea, AG; Heimann, W; Kirchengast, M; Kretzschmar, R; Safer, A, 1988)
"Effect of UM-272, a dimethyl propranolol has been studied in experimental myocardial necrosis induced by isoproterenol (ISP, 85 mg/kg, SC X 2 days) in rats."3.67Alterations in isoproterenol-induced cardiac metabolic changes by a quaternary analog of propranolol, UM-272. ( Gupta, M; Gupta, MP; Manchanda, SC; Seth, SD; Srivastava, LM, 1985)
" Distribution of [45Ca]CaCl2 in the mitochondria and reticulum (SR) of heart and brain mitochondria and changes of Ca-binding proteins in these organelles under NC influence have been studied in the myocardium before and after isoproterenol-induced necrosis."3.67Neurohormonal regulation of calcium in the cell. ( Alexanian, SS; Galoyan, AA; Kevorkian, GA; Muradian, MS; Voskanian, LH, 1988)
"The role of thrombocytes in the production of isoproterenol-induced cardiac necrosis was investigated in rats rendered thrombocytopenic (A) as well as in rats treated with a prostacyclin analogue (B)."3.67Essential contribution of thrombocytes to the occurrence of catecholamine-induced cardiac necroses. ( Kammermeier, H; Ober, M, 1985)
"Prophylactic effects of sulfinpyrazone (100 mg/Kg), aspirin (5 mg/Kg, 50 mg/Kg), and propranolol (2 mg/Kg, 10 mg/Kg) on myocardial necrosis and hypertrophy induced by isoproterenol were examined."3.66Effects of sulfinpyrazone, aspirin and propranolol on the isoproterenol-induced myocardial necrosis. ( Hashimoto, H; Ogawa, K, 1981)
"Isoproterenol-induced (5 mg/kg) disseminated necrosis of the rabbit myocardium led to a decrease in the efficiency of calcium pump of sarcoplasmic reticulum fragments."3.66[Effect of disseminated myocardial necrosis on ATPase activity, Ca2+ transport, and lipid peroxidation in cardiac mitochondrial and microsomal membranes]. ( Amarantova, GG; Chernysheva, GV; Kuz'mina, IL; Stoĭda, LV, 1980)
"Male and female, normotensive, Sprague-Dawley (S-D) rats, and spontaneously hypertensive rats (SHR) were subjected to acute and massive myocardial infarction with isoproterenol."3.66Hormonal and metabolic changes during acute myocardial infarction in normotensive vs hypertensive rats. ( McMurtry, JP; Wexler, BC, 1983)
"Induction of myocardial necrosis by isoproterenol produces resistance to the necrogenic effects of subsequent doses of the drug."3.66Determinants of resistance to the cardiotoxicity of isoproterenol in rats. ( Balazs, T; Bloom, S; Joseph, X; Pledger, G, 1983)
"Myocardial necrosis was produced in rats by injection of isoproterenol (80 mg per kg body weight)."3.66Changes of lipid peroxides and alpha-tocopherol in rats with experimentally induced myocardial necrosis. ( Higuchi, Y, 1982)
" Isoproterenol-induced necrosis of the heart muscle leads to a significant increase in the urea incorporated (15)N."3.66[Urea synthesis in the myocardium]. ( Minkovskiĭ, EB; Pisarenko, SI; Studneva, IM, 1980)
" Isoproterenol-induced necrosis of the heart muscle leads to a decrease in both glutamine and alanine ability to bind ammonia (20--40 and 30--45%, respectively)."3.66[Neutralization of ammonia in cardiac muscle]. ( Minkovskiĭ, EB; Pisarenko, OI; Studneva, IM, 1980)
"Myocardial necrosis was induced in male Wistar rats by isoproterenol as described by Rona et al."3.66Hypoxic tolerance of rats with isoproterenol-induced myocardial necrosis. ( Bhatia, B; Datta, K; Nijhawan, R, 1980)
"The effect of phenelzine on isoproterenol-induced myocardial necrosis was studied in rats."3.66Effect of phenelzine, a monoamine oxidase inhibitor, on isoproterenol-induced myocardial damage. ( Joshi, KC; Singh, KP; Somani, KC; Tariq, M, 1980)
"Cardiac hypertrophy was induced in rabbits by injecting either thyroxine or isoprenaline or by surgically constricting the abdominal aorta."3.66The relationship between fibrosis and lactate dehydrogenase isoenzymes in the experimental hypertrophic heart of rabbits. ( Cameron, AJ; Revis, NW, 1978)
"Changes in myocardial zinc level was followed up over a period of 5 days after producing myocardial necrosis in albino rats by subcutaneous injection of isoproterenol, 85 mg/kg body weight."3.66A temporal profile of myocardial zinc changes after isoproterenol induced cardiac necrosis. ( Ahmad, MS; Hasan, MZ; Jamil, SA; Kumar, S; Mathew, BM; Seth, TD, 1978)
"Male and female, arteriosclerotic and non-arteriosclerotic rats were treated with the anti-lipemic agent, clofibrate, for 8 days and then subjected to an acute myocardial infarction by injecting them with two large doses of isoproterenol spaced 24 hours apart."3.66Protective effects of clofibrate on isoproterenol-induced myocardial infarction in arteriosclerotic and non-arteriosclerotic rats. ( Greenberg, BP; Wexler, BC, 1978)
" Hyaluronidase, insulin, potassium chloride, and isoproterenol increased myocardial tissue damage whereas heparin and prednisolone administration resulted in decreased myocardial tissue damage after induced myocardial infarction in rats."3.66Effects of pharmacological intervention on infarct size following induced myocardial infarction in rats. ( Barletta, MA; Lau Cam, C; Lynch, VD; Staab, R, 1978)
"The changes in myocardial copper were studied over a period of five days after producing myocardial necrosis in albino rats by subcutaneous injection of isoproterenol."3.66A temporal profile of changes in myocardial copper after isoproterenol induced cardiac necrosis. ( Ahmad, M; Jamil, SA; Kumar, S; Mahdi, SQ; Mathew, BM; Seth, TD, 1978)
"Trapidil increases the isoprenalin-induced necrosis of the myocardium in the rat."3.65[Modification of the isoprenaline-induced myocardial necrosis using trapidil]. ( Lampe, D; Lange, B; Mai, I, 1976)
" The relative amounts of various polyunsaturated fatty acids in cardiac lipids influence markedly the development of myocardial necrosis and mortality following overstimulation with isoproterenol."3.65The role of myocardial membrane lipids in the development of cardiac necrosis. ( Gudbjarnason, S; Hallgrimsson, J, 1976)
"Resistance to isoproterenol-induced cardiac necrosis (IPRO) was compared in rats exposed to two types of hypoxia (i."3.65Experimental cardiac necrosis in hypobaric and anemic hypoxia. ( McGrath, JJ; Ostádal, B; Procházka, J; Rychterova, V; Wachtlova, M, 1975)
" Therefore, the myocardial metabolism was studied at different environmental temperatures in albino rats with isoproterenol-induced infarct-like myocardial necrosis."3.65Myocardial metabolism at different environmental temperatures in experimental myocardial necrosis. ( Ahmad, M; Tajuddin, M; Tariq, M, 1975)
"Isoproterenol (ISO), a drug which causes an increased strength of myocardial contraction when administered to animals in mug/kg doses, causes myocardial necrosis when given mg/kg doses."3.65Calcium as mediator of isoproterenol-induced myocardial necrosis. ( Bloom, S; Davis, DL, 1972)
" The ß-adrenergic agonist isoproterenol hydrochloride is used for its cardiac effects in a variety of different dosing regimens with high doses causing acute cardiomyocyte necrosis."1.62Type 2 MI induced by a single high dose of isoproterenol in C57BL/6J mice triggers a persistent adaptive immune response against the heart. ( Baxan, N; Bedard, O; Benson, L; Boyle, JJ; Branca, J; Forte, E; Harding, SE; Hasham, MG; Ng, FS; Panahi, M; Rosenthal, N; Sattler, S, 2021)
"Heart failure is a disease predominantly caused by an energy metabolic disorder in cardiomyocytes."1.42Modulation of fatty acid metabolism is involved in the alleviation of isoproterenol-induced rat heart failure by fenofibrate. ( Cheng, X; Li, P; Luo, S; Pan, C, 2015)
"Rats treated with isoproterenol (ISO, 85 mg/kg, sc, twice at an interval of 24 h) showed a significant increase in heart rate, mean arterial blood pressure, pressure rate index, ST elevation on ECG, and a significant increase in the levels of cardiac marker enzymes- lactate dehydrogenase, and creatine kinase in serum and a significant reduction in superoxide dismutase, and catalase and increase in thiobarbituric acid reactive substance activity in heart tissue."1.39Intravenous human umbilical cord blood improves electrophysiological and metabolic properties in ISO induced myocardial necrosis in rats. ( Kasturet, S; Mohan, M; Rokade, R, 2013)
"Myocardial infarction was produced in rats with 65, 85, 120 and 200mg/kg of ISO administered subcutaneously (sc) twice at an interval of 24h."1.35Cardioprotective activity of Ginkgo biloba Phytosomes in isoproterenol-induced myocardial necrosis in rats: a biochemical and histoarchitectural evaluation. ( Naik, SR; Panda, VS, 2008)
" All agents were also toxic to the soleus muscle (range 0."1.33Relative toxicity of cardiotonic agents: some induce more cardiac and skeletal myocyte apoptosis and necrosis in vivo than others. ( Burniston, JG; Clark, WA; Ellison, GM; Goldspink, DF; Tan, LB, 2005)
" Ws on chronic administration markedly augmented antioxidants (GSH, GSHPx, SOD, CAT) while Vit E did not stimulate the synthesis of endogenous antioxidants compared to sham."1.32Cardioprotection from ischemia and reperfusion injury by Withania somnifera: a hemodynamic, biochemical and histopathological assessment. ( Arya, DS; Bansal, P; Dinda, A; Gupta, SK; Joshi, S; Mohanty, I; Saxena, A; Talwar, KK, 2004)
" This toxic damage was initiated at lower doses of isoprenaline than in the myocardium (1 vs."1.31Characterisation of isoprenaline myotoxicity on slow-twitch skeletal versus cardiac muscle. ( Burniston, JG; Clark, WA; Colyer, J; Goldspink, DF; Ng, Y; Tan, LB, 2002)
"The resulting necrosis is believed to result, at least in part, from the leakage of lysosomal enzymes into the cytoplasm."1.29Isoproterenol-induced redistribution of endosomes in cardiac myocytes. ( Gruenberg, J; Marjomäki, V; Ritamäki, V, 1994)
"When celiprolol was administered half an hour before isoprenaline, the extent of necrosis caused by catecholamine was reduced."1.28[Effect of celiprolol on isoprenaline-induced myocardial necrosis]. ( Bednarík, B; Cerný, E; Foukal, T; Lupínek, Z; Mitova, M, 1990)
"Isoproterenol is known to cause severe myocardial lesions when given in toxic doses to adult homoiotherms."1.27Ultrastructure of isoproterenol-induced myocardial damage in chick embryos. ( Dusek, J; Ostádal, B, 1985)
"Isoproterenol (ISO) was injected in 5 mg/kg i."1.27Cardioprotective effect of prostacyclin and 7-oxo-PGI2 in rats against chronic isoproterenol damage. ( Körmöczy, PS; Kovács, G; Mikus, E; Tardos, L; Vértesi, C, 1987)
"Experimental myocardial infarction has been induced in rats by isoprenaline pretreatment and progress of the lesions has been observed histologically at intervals over a period of 6 weeks."1.26Abnormal electrocardiographic activity revealed by isolated rat heart preparations at various times after experimental myocardial infarction. ( Hicks, R; Sahyoun, HA, 1981)
"The necrosis was confirmed by ECG changes, increased serum activities of AspAT, AlAT, GPT and LDH, and by histological examination."1.26A temporal profile of changes in myocardial manganese after isoprenaline induced cardiac necrosis in albino rats. ( Ahmad, M; Hasan, MZ; Jameel, SA; Kumar, S; Mathew, BM; Seth, TD, 1979)
"The effect of inhibiting isoprenaline-induced intracellular calcium accumulation on the degree of damage produced in the rat myocardium by this amine has been investigated by simultaneously dosing rats with the calcium antagonistic drug D600."1.26The effect of a calcium antagonist (D600) on isoprenaline-induced myocardial necrosis in the rat. ( Powell, T; Rowles, PM; Steen, E; Woolf, N, 1979)
"Propranolol pretreatment decreased the accumulation of radioactivity in a dose-dependent fashion."1.26Quantitation of isoproterenol-induced myocardial necrosis with 3H-tetracycline. ( Athari-Nejad, A; Holcslaw, TL; Ryan, CF, 1979)
"Pretreatment with propranolol and pargyline protected against ISO-induced necrosis and myocardial hypertrophy, but did not influence the ISO-induced depletion of NE stores."1.25Alterations in norepinephrine pattern in the damaged myocardium in the rat. ( Bhagat, B; Dhalla, NS; Sullivan, JM, 1975)
"Trichlorofluoromethane (FC 11) provoked arrhythmia in all three animal species, dichlorodifluoromethane (FC 12) in monkeys and rats but not in mice, and difluoroethane (FC 152a) only in rats."1.25Toxicity of aerosol propellants in the respiratory and circulatory systems. VI. Influence of cardiac and pulmonary vascular lesions in the rat. ( Aviado, DM; Doherty, RE, 1975)

Research

Studies (333)

TimeframeStudies, this research(%)All Research%
pre-1990249 (74.77)18.7374
1990's17 (5.11)18.2507
2000's34 (10.21)29.6817
2010's29 (8.71)24.3611
2020's4 (1.20)2.80

Authors

AuthorsStudies
Cai, Y1
Li, Y1
Mutneja, E1
Verma, VK1
Malik, S1
Sahu, AK1
Ray, R2
Bhatia, J2
Arya, DS8
Forte, E1
Panahi, M1
Baxan, N1
Ng, FS1
Boyle, JJ1
Branca, J1
Bedard, O1
Hasham, MG1
Benson, L1
Harding, SE1
Rosenthal, N1
Sattler, S1
Asdaq, SMB1
Challa, O1
Alamri, AS1
Alsanie, WF1
Alhomrani, M1
Almutiri, AH1
Alshammari, MS1
Khwaja, S1
Mahmood, T1
Siddiqui, HH1
Murugesan, S1
Pandiyan, A1
Saravanakumar, L1
Moodley, K1
Mackraj, I1
Soraya, H1
Khorrami, A1
Garjani, A2
Maleki-Dizaji, N1
Gupta, P1
Kanwal, A1
Putcha, UK1
Bulani, Y1
Sojitra, B1
Khatua, TN1
Kuncha, M1
Banerjee, SK1
Mohan, M1
Rokade, R1
Kasturet, S1
Ojha, SK1
Sharma, C1
Golechha, MJ1
Kumari, S3
Al-Yahya, MA1
Mothana, RA1
Al-Said, MS1
El-Tahir, KE1
Al-Sohaibani, M1
Rafatullah, S1
Panda, S3
Kar, A3
Ramamurthy, V1
Lee, GJ1
Yan, L1
Vatner, DE1
Vatner, SF1
Zhou, P1
Cheng, CP1
Li, T1
Ferrario, CM1
Cheng, HJ1
Variya, BC1
Patel, SS1
Trivedi, JI1
Gandhi, HP2
Rathod, SP1
Buwa, CC1
Mahajan, UB1
Patil, CR1
Goyal, SN1
Mnafgui, K1
Hajji, R1
Derbali, F1
Gammoudi, A1
Khabbabi, G1
Ellefi, H1
Allouche, N1
Kadri, A1
Gharsallah, N1
Li, P1
Luo, S1
Pan, C1
Cheng, X1
Vutharadhi, S1
Jolapuram, U1
Kodidhela, LD1
Ning, BB1
Zhang, Y1
Wu, DD1
Cui, JG1
Liu, L2
Wang, PW1
Wang, WJ1
Zhu, WL1
Chen, Y1
Zhang, T1
Panda, VS2
Naik, SR2
Goyal, S1
Siddiqui, MK1
Siddiqui, KM1
Arora, S1
Mittal, R2
Joshi, S3
Engle, SK1
Jordan, WH1
Pritt, ML1
Chiang, AY1
Davis, MA1
Zimmermann, JL1
Rudmann, DG1
Heinz-Taheny, KM1
Irizarry, AR1
Yamamoto, Y1
Mendel, D1
Schultze, AE1
Cornwell, PD1
Watson, DE2
N, SR1
Minomo, H1
Torikai, Y1
Furukawa, T1
Uchino, H1
Kadokura, H1
Nakama, K1
Maeda, H1
Kamenosono, T1
Sukamoto, T1
Fukuzaki, K1
Nagata, R1
Kumar, V1
Asdaq, SM1
Asad, M1
Tanwar, V1
Sachdeva, J1
Kishore, K2
Nag, TC1
Thounaojam, MC2
Jadeja, RN2
Karn, SS1
Shah, JD1
Patel, DK3
Salunke, SP1
Padate, GS1
Devkar, RV3
Ramachandran, AV3
Wang, W1
Zhang, H1
Gao, H1
Kubo, H1
Berretta, RM1
Chen, X1
Houser, SR1
Shahbaz, AU1
Zhao, T1
Zhao, W1
Johnson, PL1
Ahokas, RA1
Bhattacharya, SK1
Sun, Y1
Gerling, IC1
Weber, KT2
Gayathri, V1
Ananthi, S1
Chandronitha, C1
Ramakrishnan, G1
Lakshmisundaram, R1
Sundaram, RL1
Vasanthi, HR1
Haleagrahara, N1
Julian, V1
Chakravarthi, S1
Ojha, S1
Golechha, M1
Banerjee, T1
Sharma, N1
Desai, SN1
Li, X1
Wang, X1
Guo, Y1
Deng, N1
Zheng, P1
Xu, Q1
Wu, Y1
Dai, G1
Mini, S1
Rajamohan, T1
Ng, Y1
Goldspink, DF3
Burniston, JG3
Clark, WA5
Colyer, J1
Tan, LB5
Zhao, MZ1
Wang, JR1
Carbajal, D1
Noa, M2
Molina, V1
Arruzazabala, ML1
Más, R2
Mendoza, S1
González, J1
CHAPPEL, CI3
RONA, G10
GAUDRY, R1
ANSHELEVICH, IuV1
AMELIN, AZ1
MELZOBS, MIa1
KORB, G1
TOTOVIC, V1
PRIORESCHI, P1
ROSENMANN, E2
GAZENFIELD, E1
LAUFER, A5
DAVIES, AM4
KAHN, DS5
ZBINDEN, G2
BAGDON, RE1
FERRANS, VJ3
HIBBS, RG2
BLACK, WC1
WEILBAECHER, DG1
GOYER, RA1
YIN, MW1
BOWDEN, DH1
ROSENBLUM, I2
WOHL, A2
STEIN, AA2
WEXLER, BC10
KITTINGER, GW2
SELYE, H1
VEILLEUX, R1
GRASSO, S1
Chen, S1
Jin, G1
Shan, J1
Zhang, M1
Men, Q1
Xu, L1
Ellison, GM2
Gupta, SK3
Mohanty, I1
Talwar, KK2
Dinda, A1
Bansal, P1
Saxena, A1
Suchalatha, S1
Shyamala Devi, CS1
Li, Z1
Tran, TT1
Ma, JY1
O'Young, G1
Kapoun, AM1
Chakravarty, S1
Dugar, S1
Schreiner, G1
Protter, AA1
Sood, S2
Narang, D2
Dinda, AK2
Maulik, SK3
Jiang, W1
Cai, DY1
Pan, CS1
Qi, YF1
Jiang, HF1
Geng, B1
Tang, CS1
Thomas, M1
Moolman, JA1
Hartley, S1
Van Wyk, J1
Marais, E1
Lochner, A1
Trivedi, CJ1
Balaraman, R1
Majithiya, JB1
Bothara, SB1
Chauhan, GM1
Yogeeta, SK1
Gnanapragasam, A1
Senthilkumar, S1
Subhashini, R1
Devaki, T1
Saeed, SA2
Ahmed, S2
Ansari, MN1
Bhandari, U1
Pillai, KK1
Berna, MJ1
Zhen, Y1
Hale, JE1
Ackermann, BL1
Hasić, S1
Jadrić, R1
Kiseljaković, E1
Mornjaković, Z1
Winterhalter-Jadrić, M1
Norton, GR1
Veliotes, DG1
Osadchii, O1
Woodiwiss, AJ1
Thomas, DP1
Elsherif, L1
Huang, MS1
Shai, SY1
Yang, Y1
Li, RY1
Chun, J1
Mekany, MA1
Chu, AL1
Kaufman, SJ1
Ross, RS1
Gál, G2
Leszkovszky, G1
Lendvai, J1
Judd, JT5
Pearl, W1
Balazs, T5
Titus, EO1
Mel'nik, VI1
Glebov, RN1
Hashimoto, H1
Ogawa, K1
Milei, J2
Vazquez, A1
Bolomo, NJ1
Drózdz, M1
Piwowarczyk, B1
Olczyk, K1
Wieczorek, M1
Wróblewska-Adamek, I1
Schulze, W2
Will-Shahab, L1
Chernysheva, GV1
Stoĭda, LV1
Amarantova, GG1
Kuz'mina, IL1
Bloksma, N1
Kuper, CF1
Hofhuis, FM1
Willers, JM1
Jasmin, G2
Proschek, L1
Asha Devi, S2
Seth, SD5
Gupta, MP3
Gupta, M2
Manchanda, SC4
Fleckenstein, A9
Frey, M1
Fleckenstein-Grün, G1
Boutet, M4
Turcotte, H2
Bazin, M2
Bourque, L1
Fein, FS1
Factor, SM1
Cho, S1
Miller-Green, B1
Carroll, DW1
Sonnenblick, EH1
Ostadal, B9
Pelouch, V3
Leder, O11
Parizková, J3
Faltová, E9
Mráz, M2
Spátová, M1
Zmbova, B1
Stojanova, D2
Stakic, D1
Tadzer, I1
Bogdanova, V1
McMurtry, JP1
Hüttner, I1
Joseph, X2
Bloom, S4
Pledger, G1
Woolf, N5
Davies, MJ2
Jacobs, RL1
Koppes, GM1
Higuchi, Y1
Mitova, M5
Bednarík, B4
Singal, PK1
Dhillon, KS1
Beamish, RE1
Dhalla, NS4
Sahyoun, HA1
Hicks, R1
Latte, S1
Genovese, A1
De Alfieri, W1
Polverino, W1
Cacciapuoti, AA1
Romano, M1
Chiariello, M1
Abri, O1
Hecht, A3
Ostrowski, J1
Pisarenko, SI1
Minkovskiĭ, EB2
Studneva, IM2
Pisarenko, OI1
Kapiĭ, LP1
Godfraind, T4
Khouri, G1
Sturbois, X4
Todd, GL4
Cullan, GE1
Cullan, GM1
Bhatia, B1
Datta, K1
Nijhawan, R1
Singh, KP1
Joshi, KC1
Somani, KC1
Tariq, M2
Ahmad, M4
Mathew, BM4
Kumar, S4
Seth, TD4
Hasan, MZ3
Mahdi, SQ2
Sharov, VG1
Jennings, RB1
Hawkins, HK1
Boor, PJ1
Marjomäki, V1
Ritamäki, V1
Gruenberg, J1
Pack, RJ1
Alley, MR1
Dallimore, JA1
Lapwood, KR1
Burgess, C1
Crane, J1
Teerlink, JR2
Pfeffer, JM2
Pfeffer, MA2
Pazin-Hricková, E1
Kovácsová, B1
Seginko, J1
Csabáková, L1
Herrera, M1
Magraner, J1
Ishido, S1
Yokoyama, M1
Kitazawa, S1
Maeda, S1
Ramesh, CV1
Malarvannan, P1
Jayakumar, R1
Jayasundar, S1
Puvanakrishnan, R5
Nirmala, C2
Anand, S1
Beranek, JT1
Sumitra, M2
Manikandan, P2
Kumar, DA2
Arutselvan, N2
Balakrishna, K1
Manohar, BM2
Sharma, M1
Singh, U2
Gayathri, C1
Strubelt, O3
Siegers, CP2
Bhagat, B1
Sullivan, JM1
Janke, J6
Hein, B2
Sigel, H2
Maroko, PR2
Braunwald, E2
Trickey, RJ2
Rosen, D2
Williams, R1
Shaw, MJ1
Collins, P2
Billings, CG2
Barer, GR1
Daly, JJ1
Jolly, A1
Yates, JC1
Revis, NW1
Cameron, AJ1
Ciplea, AG4
Bock, PR2
Severson, JA1
Fell, RD1
Griffith, DR1
Kapoor, NK1
Dhawan, S1
Nityanand, S1
Doherty, RE1
Aviado, DM1
Eliot, RS4
Clayton, FC3
Pieper, GM3
Pinka, J1
Jameel, SA1
Steen, E2
Powell, T1
Rowles, PM2
Saxena, KK2
Gupta, B2
Srivastava, VK1
Kulshrestha, VK2
Prasad, DN2
Ryan, CF1
Athari-Nejad, A1
Holcslaw, TL1
Klingenberg, HG1
Porta, S1
Egger, G1
Sadjak, A1
Geschwinder, I1
Núñez, RG1
Rapaport, M1
Ahmad, MS1
Jamil, SA2
Gopinath, C1
Thuring, J1
Zayed, I1
Matilla, A1
González-Campora, R1
Carrascal, E1
Galera, H1
Greenberg, BP2
Kung, HF1
Blau, M1
Barletta, MA1
Staab, R1
Lau Cam, C1
Lynch, VD1
Lanovaia, NI1
Lampe, D2
Mai, I2
Trickey, R1
Long, P1
Miller, AL1
Slezák, J3
Tribulová, N3
Rychter, Z2
Hoffmann, A1
Sierra-Callejas, JL1
Lange, B1
Braselmann, H1
Sajkiewicz, K2
Osswald, U1
Bausdorf, B1
Ramm, C1
Gudbjarnason, S2
Hallgrimsson, J1
Döring, HJ5
Gudeska, S1
Glavas, E1
Nikodijević, B1
McGrath, JJ4
Martin, LG2
Procházka, J2
Wachtlova, M1
Rychterova, V4
Tajuddin, M1
Kjekshus, JK1
Oskarsdóttir, G1
Kanke, J1
Joseph, T1
Mehta, HJ1
Adler, CP1
Benjamin, IJ2
Maulik, MG1
Roberts, SM1
Harbison, RD1
Seng, JE1
James, RC1
Hanton, G1
Longeart, L1
Lodola, A1
Edelsteinová, S1
Jezová, D1
Inczinger, F7
Vértesi, C2
Knopf, E1
Körmöczy, PS2
Lupínek, Z2
Cerný, E2
Foukal, T1
Jalil, JE1
Cho, K1
Vracko, R3
Thorning, D3
Frederickson, RG3
Li, C1
Wang, F1
Wang, LJ1
Li, CK1
Pérez-Cao, A1
Gil-Loyzaga, P1
Merchán-Pérez, A1
Tamargo, J1
Dusek, J5
Knufman, NM1
van der Laarse, A1
Vliegen, HW1
Brinkman, CJ1
el-Hage, AN1
Herman, EH1
Jordan, AW1
Kretzschmar, R1
Heimann, W1
Kirchengast, M1
Safer, A1
Middleton, KM1
Henderson, AH1
Lewis, MJ1
Srivastava, LM1
Barrett, RJ1
Harleman, JH1
Joseph, EC1
Richter, KD1
Mikus, E1
Tardos, L1
Kovács, G1
Cunningham, D2
Galoyan, AA1
Kevorkian, GA1
Voskanian, LH1
Alexanian, SS1
Muradian, MS1
White, FP1
White, SR1
Li, ZH1
Devecka, V1
Dostál, J1
Bózner, A7
Baroldi, G1
Pavlenko, VS1
Slepushkin, VD1
Zoloev, GK1
Titov, MI1
Okerberg, CV1
Van Vleet, JF1
Meng, XZ1
Yu, WH1
Su, Y1
Kammermeier, H1
Ober, M1
Yarom, R1
Tsuboi, T2
Ishikawa, K2
Osawa, Y2
Yoshida, K2
Shimizu, M2
Turek, Z3
Kalus, M2
Poupa, O6
Stanton, HC1
Jelínková, M2
Pilný, J2
Deyl, Z3
Vrzalová, Z1
Masáreová, E4
Pfitzer, P1
Knieriem, HJ1
Dietrich, H1
Herbertz, G1
Leonteva, TA1
Semenova, LA1
Guy, CR1
Chiche, P1
Berkman, M1
Favre, M1
Gouin, B1
Tabet, J1
Iskushev, VS1
Lifshits, RI1
Slobodin, VB1
Earl, FL1
Bierbower, GW1
Weinberger, MA1
Breining, H1
Leszkovszky, GP1
Dorigotti, L1
Gaetani, M1
Glässer, AH1
Turolla, E1
Vedeneeva, ZI1
Martorana, PA1
Moe, RA1
Brown, LL1
Gryglewski, RJ1
Kulig, A2
Kostka-Trabka, E2
Willen, D1
Lukaciková, E1
Davis, D1
Morin, Y1
Côté, G1
Otte, JB1
Lambotte, L1
Squifflet, JP1
Moriau, M1
Kestens, PJ1
Csáky, L2
Szabó, J2
Szegi, J1
Libby, P1
Maramaa, SIa1
Khaage, SA1
Lehr, D2
Seelig, MS1
Osborne, BE1
Dent, NJ1
Varley, KG1
Albrecht, I1
Parízková, F1
Pilný, F1
Lutmer, RF1
Bramante, PO1
Nirdlinger, EL1
Magnusson, G1
Hansson, E1
Blanárik, P1
Baláz, V1
Arora, RB1
Basu, AK1
Kapoor, SC1
Taneja, V1
Coppi, G1
Bonardi, G1
Sapsford, RN1
Blackstone, EH1
Kirklin, JW1
Karp, RB1
Kouchoukos, NT1
Pacifico, AD1
Roe, CR1
Bradley, EL1
Rakusan, K1
Aschenbrenner, V1
Mĕstan, J1
Selve, H1
Csapó, Z1
Kozlovský, J1
Brown, ML2
Pachinger, O1
Cagánová, A1
Davis, DL1
Leon, AS2
White, FC1
Bloor, CM2
Saviano, MA1
Gryglewski, R1
Kowalczykowa, J1
Swies, J1
Meltzer, Y1
Guschwan, A1
Griminger, P1
Walsh, JJ1
Burch, GE1
Bajusz, E1
Reindell, A1
Pitt, B1
Smrz, M1
Janiec, W1
Wolański, A1
Pasiewicz, J1
Souhrada, J1
Bullard, RW1
Farber, E1
Baserga, R1
Moudgil, LR1
Krofta, K1
Wenzel, DG2
Stark, LG1
Kennedy, JH1
Alousi, M1
Homi, J1
Scriabine, A1
Stebbins, RB1
Gazenfeld, E1
Chau, RY1
Kako, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Scheme of Primary Prevention of Infection by COVID-19, in Workers: Phase II Controlled Clinical Trial, to be Carried Out in Medellín-Antioquia[NCT04420260]152 participants (Actual)Interventional2021-03-18Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

11 reviews available for isoproterenol and Necrosis

ArticleYear
EXPERIMENTAL CARDIAC NECROSIS.
    Biochemical clinics, 1963, Volume: 2

    Topics: Chlorides; Desoxycorticosterone; Dihydrotachysterol; Heart; Humans; Hypokalemia; Isoproterenol; Magn

1963
STUDIES ON INFARCT-LIKE MYOCARDIAL NECROSIS PRODUCED BY ISOPROTERENOL: A REVIEW.
    Revue canadienne de biologie, 1963, Volume: 22

    Topics: Desoxycorticosterone; Dogs; Epinephrine; Heart Diseases; Hyperthyroidism; Hypokalemia; Isoproterenol

1963
A molecular biologic approach to cardiac toxicology.
    Advances in experimental medicine and biology, 1983, Volume: 161

    Topics: Acrylamides; Animals; Calcium; Cnidarian Venoms; Coronary Disease; Doxorubicin; Egtazic Acid; Electr

1983
Influence of environmental stress on pathogenesis of sudden cardiac death.
    Federation proceedings, 1977, Volume: 36, Issue:5

    Topics: Adenosine Triphosphate; Animals; Catecholamines; Coronary Circulation; Coronary Disease; Death, Sudd

1977
Magnesium deficiency cardiomyopathy.
    The American journal of cardiovascular pathology, 1988, Volume: 2, Issue:1

    Topics: Animals; Cardiomyopathies; Coronary Vessels; Humans; Isoproterenol; Magnesium Deficiency; Myocardial

1988
Catecholamine cardiotoxicity.
    Journal of molecular and cellular cardiology, 1985, Volume: 17, Issue:4

    Topics: Animals; Calcium; Cardiomyopathies; Catecholamines; Cell Membrane Permeability; Coronary Circulation

1985
Experimental catecholamine-induced myocardial necrosis. I. Morphology, quantification and regional distribution of acute contraction band lesions.
    Journal of molecular and cellular cardiology, 1985, Volume: 17, Issue:4

    Topics: Animals; Cardiomyopathies; Catecholamines; Constriction, Pathologic; Dogs; Hemodynamics; Isoproteren

1985
The pathophysiologic vulnerability of the subendocardium of the left ventricle.
    Advances in cardiology, 1973, Volume: 9

    Topics: Arrhythmias, Cardiac; Capillaries; Cardiomegaly; Coronary Disease; Coronary Vessels; Endocardium; He

1973
Toxic agents and cardiomyopathies.
    Cardiovascular clinics, 1972, Volume: 4, Issue:1

    Topics: Alcoholism; Animals; Autopsy; Cardiomyopathies; Cobalt; Disease Models, Animal; Drug-Related Side Ef

1972
Reduction of infarct size following coronary occlusion.
    Circulation research, 1974, Volume: 35 Suppl 3

    Topics: Anaerobiosis; Animals; Assisted Circulation; Coronary Vessels; Creatine Kinase; Electrocardiography;

1974
The pluricausal cardiopathies.
    Annals of the New York Academy of Sciences, 1969, Jan-31, Volume: 156, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Antimalarials; Calcinosis; Cardiac Glycosides; Deficiency Diseases;

1969

Trials

1 trial available for isoproterenol and Necrosis

ArticleYear
Coronary perfusion versus cold ischemic arrest during aortic valve surgery. A randomized study.
    Circulation, 1974, Volume: 49, Issue:6

    Topics: Adult; Aged; Aortic Valve; Arrhythmias, Cardiac; Cardiac Catheterization; Cardiac Output; Creatine K

1974

Other Studies

321 other studies available for isoproterenol and Necrosis

ArticleYear
Protective Effect of Sciadopitysin against Isoproternol-Induced Myocardial Infarction in Rats.
    Pharmacology, 2020, Volume: 105, Issue:5-6

    Topics: Animals; Biflavonoids; Cardiotonic Agents; Heart; Isoproterenol; Male; Myocardial Infarction; Myocar

2020
Erdosteine salvages cardiac necrosis: Novel effect through modulation of MAPK and Nrf-2/HO-1 pathway.
    Journal of biochemical and molecular toxicology, 2020, Volume: 34, Issue:12

    Topics: Animals; Biomarkers; Cardiomyopathies; Cytokines; Dose-Response Relationship, Drug; Heme Oxygenase (

2020
Type 2 MI induced by a single high dose of isoproterenol in C57BL/6J mice triggers a persistent adaptive immune response against the heart.
    Journal of cellular and molecular medicine, 2021, Volume: 25, Issue:1

    Topics: Adaptive Immunity; Adoptive Transfer; Animals; Dendritic Cells; Disease Models, Animal; Female; Fibr

2021
Cytoprotective Potential of Aged Garlic Extract (AGE) and Its Active Constituent, S-allyl-l-cysteine, in Presence of Carvedilol during Isoproterenol-Induced Myocardial Disturbance and Metabolic Derangements in Rats.
    Molecules (Basel, Switzerland), 2021, May-27, Volume: 26, Issue:11

    Topics: Animals; Antioxidants; Carvedilol; Catalase; Creatine Kinase, MB Form; Cysteine; Female; Garlic; Hea

2021
Effect of ethanolic extract of Cyperus rotundus L. against isoprenaline induced cardiotoxicity.
    Indian journal of experimental biology, 2016, Volume: 54, Issue:10

    Topics: Adrenergic beta-1 Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarker

2016
Protective role of wild garlic on isoproterenol-induced myocardial necrosis in wistar rats.
    Journal of ethnopharmacology, 2019, Jun-12, Volume: 237

    Topics: Amaryllidaceae; Animals; Cardiotonic Agents; Caspases; fas Receptor; Heart Rate; Isoproterenol; Male

2019
Acute treatment with metformin improves cardiac function following isoproterenol induced myocardial infarction in rats.
    Pharmacological reports : PR, 2012, Volume: 64, Issue:6

    Topics: Administration, Oral; Animals; Arterial Pressure; Cardiotonic Agents; Disease Models, Animal; Dose-R

2012
Cardioprotective effect of ritonavir, an antiviral drug, in isoproterenol induced myocardial necrosis: a new therapeutic implication.
    Journal of translational medicine, 2013, Mar-26, Volume: 11

    Topics: Animals; Antioxidants; Body Weight; Cardiomyopathies; Cardiotonic Agents; Glucose Transporter Type 4

2013
Intravenous human umbilical cord blood improves electrophysiological and metabolic properties in ISO induced myocardial necrosis in rats.
    Indian journal of experimental biology, 2013, Volume: 51, Issue:3

    Topics: Animals; Antioxidants; Blood Pressure; Cardiotoxins; Creatine Kinase; Dose-Response Relationship, Dr

2013
Licorice treatment prevents oxidative stress, restores cardiac function, and salvages myocardium in rat model of myocardial injury.
    Toxicology and industrial health, 2015, Volume: 31, Issue:2

    Topics: Animals; Glycyrrhiza; Heart; Hemodynamics; Isoproterenol; Lipid Peroxidation; Male; Myocardial Infar

2015
Citrus medica "Otroj": attenuates oxidative stress and cardiac dysrhythmia in isoproterenol-induced cardiomyopathy in rats.
    Nutrients, 2013, Oct-28, Volume: 5, Issue:11

    Topics: Animals; Antioxidants; Biomarkers; Biphenyl Compounds; Cardiomyopathies; Citrus; Female; Flavonoids;

2013
Cardioprotective effect of vincristine on isoproterenol-induced myocardial necrosis in rats.
    European journal of pharmacology, 2014, Jan-15, Volume: 723

    Topics: Adenosine Triphosphatases; Animals; Cardiotonic Agents; Catalase; Glutathione; Glutathione Peroxidas

2014
Combined Effects of Vincristine and Quercetin in Reducing Isoproterenol-Induced Cardiac Necrosis in Rats.
    Cardiovascular toxicology, 2015, Volume: 15, Issue:4

    Topics: Animals; Antioxidants; Biomarkers; Cardiomyopathies; Cytoprotection; Disease Models, Animal; Drug Th

2015
Mst1 inhibition rescues β1-adrenergic cardiomyopathy by reducing myocyte necrosis and non-myocyte apoptosis rather than myocyte apoptosis.
    Basic research in cardiology, 2015, Volume: 110, Issue:2

    Topics: Adrenergic beta-1 Receptor Agonists; Animals; Blotting, Western; Cardiomyopathies; Disease Models, A

2015
Modulation of cardiac L-type Ca2+ current by angiotensin-(1-7): normal versus heart failure.
    Therapeutic advances in cardiovascular disease, 2015, Volume: 9, Issue:6

    Topics: Angiotensin I; Animals; Bradykinin; Calcium Channels, L-Type; Calcium Signaling; Cardiotonic Agents;

2015
Comparative evaluation of HMG CoA reductase inhibitors in experimentally-induced myocardial necrosis: Biochemical, morphological and histological studies.
    European journal of pharmacology, 2015, Oct-05, Volume: 764

    Topics: Adenosine Triphosphatases; Animals; Atorvastatin; Blood Glucose; Cardiotonic Agents; Catalase; Chole

2015
Apigenin Attenuates β-Receptor-Stimulated Myocardial Injury Via Safeguarding Cardiac Functions and Escalation of Antioxidant Defence System.
    Cardiovascular toxicology, 2016, Volume: 16, Issue:3

    Topics: Animals; Antioxidants; Apigenin; Biomarkers; Catalase; Creatine Kinase, MB Form; Cytoprotection; Dis

2016
Anti-inflammatory, Antithrombotic and Cardiac Remodeling Preventive Effects of Eugenol in Isoproterenol-Induced Myocardial Infarction in Wistar Rat.
    Cardiovascular toxicology, 2016, Volume: 16, Issue:4

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents; Antioxidants; Biomarker

2016
Modulation of fatty acid metabolism is involved in the alleviation of isoproterenol-induced rat heart failure by fenofibrate.
    Molecular medicine reports, 2015, Volume: 12, Issue:6

    Topics: Animals; Cells, Cultured; Energy Metabolism; Fatty Acids; Fenofibrate; Heart Failure; Hypolipidemic

2015
Nutraceutical inherent of Spinacia oleracea Linn. methanolic leaf extract ameliorates isoproterenol induced myocardial necrosis in male albino Wistar rats via mitigating inflammation.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 85

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Cardiomyopathies; Chromatography, High Pressure Liquid

2017
Luteolin-7-diglucuronide attenuates isoproterenol-induced myocardial injury and fibrosis in mice.
    Acta pharmacologica Sinica, 2017, Volume: 38, Issue:3

    Topics: Animals; Antioxidants; Cardiomyopathies; Cardiotonic Agents; Extracellular Matrix Proteins; Fibrosis

2017
Cardioprotective activity of Ginkgo biloba Phytosomes in isoproterenol-induced myocardial necrosis in rats: a biochemical and histoarchitectural evaluation.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2008, Volume: 60, Issue:4-5

    Topics: Adrenergic beta-Agonists; Animals; Ginkgo biloba; Heart; Isoproterenol; Myocardial Infarction; Myoca

2008
Cardioprotective effect of 'Khamira Abresham Hakim Arshad Wala' a unani formulation in isoproterenol-induced myocardial necrosis in rats.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2010, Volume: 62, Issue:1

    Topics: Animals; Cardiotonic Agents; Catalase; Creatine Kinase, MB Form; Glutathione; Heart; Hemodynamics; I

2010
Qualification of cardiac troponin I concentration in mouse serum using isoproterenol and implementation in pharmacology studies to accelerate drug development.
    Toxicologic pathology, 2009, Volume: 37, Issue:5

    Topics: Animals; Aspartate Aminotransferases; Biomarkers; Cardiotonic Agents; Creatine Kinase; Dose-Response

2009
Evaluation of cardioprotective activity of Ginkgo biloba and Ocimum sanctum in rodents.
    Alternative medicine review : a journal of clinical therapeutic, 2009, Volume: 14, Issue:2

    Topics: Animals; Antioxidants; Cardiotonic Agents; Dose-Response Relationship, Drug; Ginkgo biloba; Isoprote

2009
Characteristics of troponins as myocardial damage biomarkers in cynomolgus monkeys.
    The Journal of toxicological sciences, 2009, Volume: 34, Issue:6

    Topics: Animals; Biomarkers; Cardiomyopathies; Isoproterenol; Macaca fascicularis; Male; Myocardium; Necrosi

2009
Influence of betel quid on effect of calcium channel blockers on isoprenaline induced myocardial necrosis in mice.
    Indian journal of experimental biology, 2009, Volume: 47, Issue:9

    Topics: Animals; Areca; Body Weight; Calcium; Calcium Channel Blockers; Isoproterenol; L-Lactate Dehydrogena

2009
Dose-dependent actions of curcumin in experimentally induced myocardial necrosis: a biochemical, histopathological, and electron microscopic evidence.
    Cell biochemistry and function, 2010, Volume: 28, Issue:1

    Topics: Administration, Oral; Animals; Creatine Kinase; Curcumin; Disease Models, Animal; Dose-Response Rela

2010
Cardioprotective effect of Sida rhomboidea. Roxb extract against isoproterenol induced myocardial necrosis in rats.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2011, Volume: 63, Issue:4

    Topics: Animals; Cardiotonic Agents; Heart; Isoproterenol; Lipid Peroxidation; Lipids; Male; Malvaceae; Myoc

2011
{beta}1-Adrenergic receptor activation induces mouse cardiac myocyte death through both L-type calcium channel-dependent and -independent pathways.
    American journal of physiology. Heart and circulatory physiology, 2010, Volume: 299, Issue:2

    Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists;

2010
Pomegranate (Punica granatum L.) juice supplementation attenuates isoproterenol-induced cardiac necrosis in rats.
    Cardiovascular toxicology, 2010, Volume: 10, Issue:3

    Topics: Adenosine Triphosphatases; Adrenergic beta-Agonists; Animals; Antioxidants; Beverages; Creatine Kina

2010
Calcium and zinc dyshomeostasis during isoproterenol-induced acute stressor state.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 300, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Antioxidants; Calcium; Capillary Per

2011
Cardioprotective effect of Nerium oleander flower against isoproterenol-induced myocardial oxidative stress in experimental rats.
    Journal of cardiovascular pharmacology and therapeutics, 2011, Volume: 16, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Biomarkers; Cardiotonic Agents; Dose-Response Relationship, Drug;

2011
N-acetylcysteine offers cardioprotection by decreasing cardiac lipid hydroperoxides and 8-isoprostane level in isoproterenol-induced cardiotoxicity in rats.
    Cardiovascular toxicology, 2011, Volume: 11, Issue:4

    Topics: Acetylcysteine; Animals; Body Weight; Cardiotonic Agents; Creatine Kinase, MB Form; Dinoprost; Drug

2011
Protective effect of Emblica officinalis (amla) on isoproterenol-induced cardiotoxicity in rats.
    Toxicology and industrial health, 2012, Volume: 28, Issue:5

    Topics: Analysis of Variance; Animals; Antioxidants; Biomarkers; Blood Pressure; Cardiotonic Agents; Cardiot

2012
Combined effects of quercetin and atenolol in reducing isoproterenol-induced cardiotoxicity in rats: possible mediation through scavenging free radicals.
    Cardiovascular toxicology, 2012, Volume: 12, Issue:3

    Topics: Administration, Oral; Adrenergic beta-Agonists; Animals; Antihypertensive Agents; Atenolol; Cardioto

2012
Cardio protective effect of Coriandrum sativum L. on isoproterenol induced myocardial necrosis in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2012, Volume: 50, Issue:9

    Topics: Animals; Cardiotonic Agents; Heart; Isoproterenol; Male; Necrosis; Plant Extracts; Rats; Rats, Wista

2012
Regulation of endothelial nitric oxide synthase and asymmetric dimethylarginine by matrine attenuates isoproterenol-induced acute myocardial injury in rats.
    The Journal of pharmacy and pharmacology, 2012, Volume: 64, Issue:8

    Topics: Alkaloids; Amidohydrolases; Animals; Arginine; Catechol O-Methyltransferase; Glycogen Synthase Kinas

2012
Cardioprotective effect of coconut kernel protein in isoproterenol administered rats.
    Indian journal of biochemistry & biophysics, 2002, Volume: 39, Issue:3

    Topics: Adenosine Triphosphate; Animals; Arginine; Aspartate Aminotransferase, Cytoplasmic; Body Weight; Car

2002
Characterisation of isoprenaline myotoxicity on slow-twitch skeletal versus cardiac muscle.
    International journal of cardiology, 2002, Volume: 86, Issue:2-3

    Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Isoproterenol

2002
[Experimental study of protective effect of tongxinluo capsule on isoproterenol induced myocardial injury in rats].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2001, Volume: 21, Issue:1

    Topics: Animals; Apoptosis; Capsules; Cardiomyopathies; Drug Combinations; Drugs, Chinese Herbal; Isoprotere

2001
Effect of D-003 on isoproterenol-induced myocardial necrosis in rats.
    Journal of medicinal food, 2003,Spring, Volume: 6, Issue:1

    Topics: Animals; Aspirin; Disease Models, Animal; Fatty Acids; Isoproterenol; Male; Myocardial Infarction; M

2003
The influence of adrenal cortical steroids on cardiac necrosis produced by isoproterenol.
    Acta endocrinologica, 1959, Volume: 32

    Topics: Adrenal Cortex Hormones; Heart; Heart Diseases; Humans; Isoproterenol; Necrosis; Sympathomimetics

1959
[Experimental induction of necroses in the myocardium with isadrine (isopropylnoradrenalin)].
    Kardiologiia, 1963, Volume: 3

    Topics: Isoproterenol; Myocardial Infarction; Myocardium; Necrosis

1963
[ON LATE CHANGES IN THE RAT MYOCARDIUM AFTER EXPERIMENTAL CORONARY INSUFFICIENCY].
    Frankfurter Zeitschrift fur Pathologie, 1963, Nov-18, Volume: 73

    Topics: Coronary Disease; Eosinophilia; Fluorescence; Isoproterenol; Leukocyte Disorders; Myocardium; Necros

1963
ISOPROTERENOL INDUCED MYOCARDIAL LESIONS IN THE IMMUNIZED AND NON-IMMUNIZED RAT. 1. HISTOPATHOLOGICAL LESIONS IN NORMAL RATS.
    Pathologia et microbiologia, 1964, Volume: 27

    Topics: Antibodies; Heart; Hypokalemia; Immunization; Isoproterenol; Necrosis; Pathology; Pharmacology; Pota

1964
ISOPROTERENOL-INDUCED HEART NECROSIS, AN EXPERIMENTAL MODEL FOR THE STUDY OF ANGINA PECTORIS AND MYOCARDIAL INFARCT.
    Revue canadienne de biologie, 1963, Volume: 22

    Topics: Angina Pectoris; Aspartate Aminotransferases; Heart; Isocarboxazid; Isoproterenol; L-Lactate Dehydro

1963
ISOPROTERENOL-INDUCED MYOCARDIAL NECROSIS. A HISTOCHEMICAL AND ELECTRON MICROSCOPIC STUDY.
    American heart journal, 1964, Volume: 68

    Topics: Coronary Disease; Electron Transport Complex IV; Electrons; Fluorescence; Glycogen; Heart Diseases;

1964
TAURINE EXCRETION FOLLOWING DRUG-INDUCED MUSCLE NECROSIS AND X-IRRADIATION.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 116

    Topics: Diaphragm; Heart Diseases; Isoproterenol; Muscular Diseases; Necrosis; Radiation Injuries; Radiation

1964
STUDIES IN CARDIAC NECROSIS. I. PRODUCTION OF CARDIAC LESIONS WITH SYMPATHOMIMETIC AMINES.
    Toxicology and applied pharmacology, 1965, Volume: 7

    Topics: Amphetamine; Amphetamines; Animals; Cats; Cricetinae; Dogs; Ephedrine; Epinephrine; Heart Diseases;

1965
STUDIES IN CARDIAC NECROSIS. II. CARDIOVASCULAR EFFECTS OF SYMPATHOMIMETIC AMINES PRODUCING CARDIAC LESIONS.
    Toxicology and applied pharmacology, 1965, Volume: 7

    Topics: Blood Flow Velocity; Cats; Ephedrine; Heart; Heart Diseases; Heart Function Tests; Heart Rate; Isopr

1965
STEROIDS PRODUCED IN VITRO BY ADRENAL GLANDS OF NORMAL AND ARTERIOSCLEROTIC RATS DURING AND AFTER DRUG-INDUCED MYOCARDIAL NECROSIS.
    Circulation research, 1965, Volume: 16

    Topics: Adrenal Cortex Hormones; Adrenal Glands; Aldosterone; Arteriosclerosis; Heart Failure; In Vitro Tech

1965
Protection, by coronary ligature, against isoproterenol-induced myocardial necroses.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1960, Volume: 104

    Topics: Coronary Vessels; Heart; Isoproterenol; Ligation; Myocardial Infarction; Myocardium; Necrosis; Sympa

1960
[Cardioprotective effect and influence on NOS expression of Montelukast sodium in rats].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2003, Volume: 38, Issue:11

    Topics: Acetates; Animals; Cardiotonic Agents; Cyclopropanes; Female; Isoproterenol; Leukotriene Antagonists

2003
Catecholamine-induced apoptosis and necrosis in cardiac and skeletal myocytes of the rat in vivo: the same or separate death pathways?
    Experimental physiology, 2004, Volume: 89, Issue:4

    Topics: Animals; Apoptosis; Catecholamines; Heart Ventricles; Isoproterenol; Male; Muscle Fibers, Skeletal;

2004
Cardioprotection from ischemia and reperfusion injury by Withania somnifera: a hemodynamic, biochemical and histopathological assessment.
    Molecular and cellular biochemistry, 2004, Volume: 260, Issue:1-2

    Topics: Animals; Blood Pressure; Catalase; Creatine Kinase; Female; Glutathione; Glutathione Peroxidase; Hea

2004
Protective effect of Terminalia chebula against experimental myocardial injury induced by isoproterenol.
    Indian journal of experimental biology, 2004, Volume: 42, Issue:2

    Topics: Adrenergic beta-Agonists; Alanine Transaminase; Animals; Aspartate Aminotransferases; Fruit; Heart;

2004
p38 alpha mitogen-activated protein kinase inhibition improves cardiac function and reduces myocardial damage in isoproterenol-induced acute myocardial injury in rats.
    Journal of cardiovascular pharmacology, 2004, Volume: 44, Issue:4

    Topics: Acute Disease; Animals; Blood Pressure; Body Weight; Cardiotonic Agents; Gene Expression; Injections

2004
Chronic oral administration of Ocimum sanctum Linn. augments cardiac endogenous antioxidants and prevents isoproterenol-induced myocardial necrosis in rats.
    The Journal of pharmacy and pharmacology, 2005, Volume: 57, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Antioxidants; Catalase; Female; Glutathione; Glutathione Peroxida

2005
Changes in production and metabolism of brain natriuretic peptide in rats with myocardial necrosis.
    European journal of pharmacology, 2005, Jan-10, Volume: 507, Issue:1-3

    Topics: Animals; Isoproterenol; Male; Myocardium; Natriuretic Peptide, Brain; Necrosis; Pyridines; Rats; Rat

2005
Dietary palm olein oil augments cardiac antioxidant enzymes and protects against isoproterenol-induced myocardial necrosis in rats.
    The Journal of pharmacy and pharmacology, 2005, Volume: 57, Issue:11

    Topics: Animals; Catalase; Diet; Dietary Fats, Unsaturated; Female; Glutathione Peroxidase; Heart; Isoproter

2005
Relative toxicity of cardiotonic agents: some induce more cardiac and skeletal myocyte apoptosis and necrosis in vivo than others.
    Cardiovascular toxicology, 2005,Fall, Volume: 5, Issue:4

    Topics: Animals; Apoptosis; Cardiotonic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; He

2005
Inhibition of myocardial apoptosis by ischaemic and beta-adrenergic preconditioning is dependent on p38 MAPK.
    Cardiovascular drugs and therapy, 2006, Volume: 20, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Anisomycin; Apoptosis; Enzyme Activators; Imidazoles; In Vitro Te

2006
Effect of atorvastatin treatment on isoproterenol-induced myocardial infarction in rats.
    Pharmacology, 2006, Volume: 77, Issue:1

    Topics: Adenosine Triphosphatases; Animals; Atorvastatin; Body Weight; Catalase; Glutathione; Heart; Heptano

2006
Cardioprotective activity of A.V. Circulo in isoproterenol-induced myocardial necrosis.
    Journal of herbal pharmacotherapy, 2005, Volume: 5, Issue:4

    Topics: Administration, Oral; Animals; Cardiotonic Agents; Female; Isoproterenol; Male; Myocardial Infarctio

2005
Synergistic salubrious effect of ferulic acid and ascorbic acid on membrane-bound phosphatases and lysosomal hydrolases during experimental myocardial infarction in rats.
    Life sciences, 2006, Dec-23, Volume: 80, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Ascorbic Acid; Cardiotonic Agents; C

2006
Anti-ischemic effects of nimesulide, a cyclooxygenase-2 inhibitor on the ischemic model of rabbit induced by isoproterenol.
    Archives of pharmacal research, 2006, Volume: 29, Issue:11

    Topics: Adrenergic beta-Agonists; Animals; Coronary Circulation; Creatine Kinase; Cyclooxygenase 2 Inhibitor

2006
Ethanolic Zingiber officinale R. extract pretreatment alleviates isoproterenol-induced oxidative myocardial necrosis in rats.
    Indian journal of experimental biology, 2006, Volume: 44, Issue:11

    Topics: Animals; Antioxidants; Biomarkers; Ethanol; Female; Isoproterenol; Lipid Peroxidation; Male; Myocard

2006
Strategic use of immunoprecipitation and LC/MS/MS for trace-level protein quantification: myosin light chain 1, a biomarker of cardiac necrosis.
    Analytical chemistry, 2007, Jun-01, Volume: 79, Issue:11

    Topics: Amino Acid Sequence; Animals; Biomarkers; Chromatography, Liquid; Heart Diseases; Immunoprecipitatio

2007
Troponin T and histological characteristics of rat myocardial infarction induced by isoproterenol.
    Bosnian journal of basic medical sciences, 2007, Volume: 7, Issue:3

    Topics: Animals; Body Weight; Cardiotonic Agents; Creatine Kinase; Heart; Isoproterenol; Male; Myocardial In

2007
Susceptibility to systolic dysfunction in the myocardium from chronically infarcted spontaneously hypertensive rats.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:1

    Topics: Animals; Apoptosis; Cardiotonic Agents; Coronary Vessels; Disease Models, Animal; Hypertension; Isop

2008
Combined deficiency of dystrophin and beta1 integrin in the cardiac myocyte causes myocardial dysfunction, fibrosis and calcification.
    Circulation research, 2008, May-09, Volume: 102, Issue:9

    Topics: Adrenergic beta-Agonists; Animals; Calcinosis; Calcium-Binding Proteins; Cardiomyopathies; Cell Adhe

2008
New aspects of cyclooxygenase-2 inhibition in myocardial infarction and ischaemia.
    Research communications in molecular pathology and pharmacology, 2005, Volume: 117-118

    Topics: Adrenergic beta-Agonists; Animals; Cardiotonic Agents; Creatine Kinase; Cyclooxygenase 2; Cyclooxyge

2005
Quantitative evaluation of morphologic changes in experimentally induced myocardial necrosis.
    Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1966, Volume: 14, Issue:6

    Topics: Animals; Guanethidine; Heart Diseases; Iproniazid; Isoproterenol; Male; Monoamine Oxidase Inhibitors

1966
Responses to drug-induced myocardial necrosis in rats with various degrees of arteriosclerosis.
    Circulation research, 1967, Volume: 20, Issue:1

    Topics: Adrenal Glands; Animals; Arteriosclerosis; Blood Circulation; Cardiomyopathies; Cholesterol; Coronar

1967
Survival of stressed rats following experimental cardiac necrosis.
    Experientia, 1967, Feb-15, Volume: 23, Issue:2

    Topics: Animals; Dietary Fats; Heart Diseases; Isoproterenol; Male; Necrosis; Physical Exertion; Rats; Stres

1967
[Dynamics of the change in Na, K-ATPase activity during the development of isoproterenol-induced myocardial necrosis in rats].
    Biulleten' eksperimental'noi biologii i meditsiny, 1984, Volume: 98, Issue:8

    Topics: Adenosine Triphosphatases; Animals; Ca(2+) Mg(2+)-ATPase; Heart; Isoproterenol; Ligands; Myocardium;

1984
Effects of sulfinpyrazone, aspirin and propranolol on the isoproterenol-induced myocardial necrosis.
    Japanese heart journal, 1981, Volume: 22, Issue:4

    Topics: Animals; Aspirin; Body Weight; Creatine Kinase; Cyclic AMP; Heart; Isoproterenol; Male; Myocardial I

1981
An overall review on prenylamine mechanisms of action in experimental models of myocardial damage.
    Cardiology, 1982, Volume: 69, Issue:4

    Topics: Angina Pectoris; Animals; Calcium; Cebus; Disease Models, Animal; Electrocardiography; Female; Heart

1982
Leukocyte collagenolytic activity in normal and hydrazinophthalazine-treated rats during isoprenaline-induced cardiomyopathy.
    Experimental pathology, 1983, Volume: 23, Issue:4

    Topics: Animals; Cardiomyopathies; Cathepsins; Collagen; Hydralazine; Isoproterenol; Leukocytes; Macrophages

1983
[Behavior of adenylate cyclase in ischemic and necrotic myocardial tissue].
    Acta histochemica. Supplementband, 1984, Volume: 30

    Topics: Adenylyl Cyclases; Animals; Coronary Disease; Disease Models, Animal; Histocytochemistry; Isoprotere

1984
[Effect of disseminated myocardial necrosis on ATPase activity, Ca2+ transport, and lipid peroxidation in cardiac mitochondrial and microsomal membranes].
    Biulleten' eksperimental'noi biologii i meditsiny, 1980, Volume: 89, Issue:5

    Topics: Adenosine Triphosphatases; Animals; Calcium; Cardiomyopathies; Dinitrophenols; Isoproterenol; Lipid

1980
Role of vasoactive amines in the antitumor activity of endotoxin.
    Immunopharmacology, 1984, Volume: 7, Issue:3-4

    Topics: Animals; Cell Division; Endotoxins; Epinephrine; Female; Glycoproteins; Growth Inhibitors; Isoproter

1984
Calcium and myocardial cell injury. An appraisal in the cardiomyopathic hamster.
    Canadian journal of physiology and pharmacology, 1984, Volume: 62, Issue:7

    Topics: Animals; Calcium; Calcium Channel Blockers; Cardiomyopathies; Cricetinae; Female; Isoproterenol; Mal

1984
Depletion of myocardial potassium as a function of age and experimental necrosis.
    Indian journal of experimental biology, 1984, Volume: 22, Issue:3

    Topics: Aging; Animals; Female; Isoproterenol; Myocardial Infarction; Myocardium; Necrosis; Potassium; Rats;

1984
Oxyfedrine and propranolol. A comparative experimental approach to protect myocardium against isoprenaline-induced myocardial necrosis.
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:6

    Topics: Animals; Cardiomyopathies; Female; Glycolysis; Isoproterenol; Male; Myocardium; Necrosis; Oxyfedrine

1984
Consequences of uncontrolled calcium entry and its prevention with calcium antagonists.
    European heart journal, 1983, Volume: 4 Suppl H

    Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Cardiomyopathies; Isoproterenol;

1983
An ultrastructural study of endocardial endothelium alterations in catecholamine-induced infarct-like necrosis.
    Revue canadienne de biologie experimentale, 1983, Volume: 42, Issue:1

    Topics: Animals; Endocardium; Endothelium; Isoproterenol; Male; Microscopy, Electron; Microscopy, Electron,

1983
Catecholamine-induced myocardial necrosis in experimental diabetes mellitus.
    Archives of pathology & laboratory medicine, 1983, Volume: 107, Issue:9

    Topics: Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Female; Isoproterenol; M

1983
Adenylate cyclase activity and localization in necrotic and non-necrotic areas of rat myocardium after injection of high doses of isoproterenol.
    Biomedica biochimica acta, 1984, Volume: 43, Issue:1

    Topics: Adenylyl Cyclases; Animals; Cardiomyopathies; Histocytochemistry; Isoproterenol; Male; Myocardium; N

1984
[Demonstration of myocardian necrosis using histochemical and histophysical methods].
    Acta histochemica. Supplementband, 1981, Volume: 24

    Topics: Animals; Calcinosis; Calcitonin; Heart; Histological Techniques; Isoproterenol; Myocardium; Necrosis

1981
Growth, food intake, motor activity and experimental cardiac necrosis in early malnourished male rats.
    Annals of nutrition & metabolism, 1982, Volume: 26, Issue:2

    Topics: Aging; Animals; Cardiomyopathies; Diet; Growth; Isoproterenol; Male; Motor Activity; Myocardium; Nec

1982
Detection of acute myocardial infarction in spontaneously hypertensive rats by 99mTc-pyrrolidino methyl tetracycline.
    European journal of nuclear medicine, 1983, Volume: 8, Issue:1

    Topics: Animals; Disease Models, Animal; Female; Hypertension; Isoproterenol; Male; Myocardial Infarction; M

1983
Hormonal and metabolic changes during acute myocardial infarction in normotensive vs hypertensive rats.
    British journal of experimental pathology, 1983, Volume: 64, Issue:2

    Topics: Animals; Body Weight; Bromocriptine; Electrocardiography; Female; Heart Rate; Hormones; Hypertension

1983
Reperfusion injury. A possible link between catecholamine-induced and ischemic myocardial alterations.
    Advances in myocardiology, 1983, Volume: 4

    Topics: Animals; Catecholamines; Cell Membrane Permeability; Coronary Circulation; Coronary Disease; Horsera

1983
Determinants of resistance to the cardiotoxicity of isoproterenol in rats.
    Toxicology and applied pharmacology, 1983, Jun-30, Volume: 69, Issue:2

    Topics: Animals; Cardiomyopathies; Drug Resistance; Drug Tolerance; Isoproterenol; Male; Necrosis; Rats; Rat

1983
Morphological variants of acute myocardial necrosis and their relationship to coronary artery thrombosis.
    Acta medica Scandinavica. Supplementum, 1980, Volume: 642

    Topics: Animals; Arteriosclerosis; Coronary Disease; Coronary Vessels; Fibrinogen; Humans; Isoproterenol; My

1980
Biochemical basis of the protective effect of propranolol pretreatment in experimental myocardial necrosis.
    Indian journal of experimental biology, 1982, Volume: 20, Issue:1

    Topics: Animals; Female; Glycogen; Heart; Isoproterenol; Male; Myocardium; Necrosis; Propranolol; Rats; Rats

1982
Myocardial necrosis associated with isoproterenol abuse: a ten-year follow-up.
    Texas medicine, 1982, Volume: 78, Issue:8

    Topics: Adult; Cardiomyopathies; Female; Follow-Up Studies; Humans; Isoproterenol; Necrosis; Substance-Relat

1982
Changes of lipid peroxides and alpha-tocopherol in rats with experimentally induced myocardial necrosis.
    Acta medica Okayama, 1982, Volume: 36, Issue:2

    Topics: Animals; Cholesterol; Heart; Hypertension; Isoproterenol; Lipid Peroxides; Liver; Male; Myocardium;

1982
Junctional complexes in regenerating endocardium.
    Journal of ultrastructure research, 1982, Volume: 79, Issue:2

    Topics: Animals; Cell Membrane; Cytoskeleton; Desmosomes; Endocardium; Intercellular Junctions; Isoprotereno

1982
[Effect of late administration of adenosintriphosphate on rat myocardium affected by isoprenaline-induced changes (author's transl)].
    Casopis lekaru ceskych, 1981, Apr-02, Volume: 120, Issue:13

    Topics: Adenosine Triphosphate; Animals; Heart; Isoproterenol; Male; Myocardium; Necrosis; Rats

1981
Protective effect of zinc against catecholamine-induced myocardial changes electrocardiographic and ultrastructural studies.
    Laboratory investigation; a journal of technical methods and pathology, 1981, Volume: 44, Issue:5

    Topics: Animals; Heart; Heart Rate; Isoproterenol; Male; Microscopy, Electron; Myocardial Contraction; Myoca

1981
Abnormal electrocardiographic activity revealed by isolated rat heart preparations at various times after experimental myocardial infarction.
    Cardiovascular research, 1981, Volume: 15, Issue:3

    Topics: Animals; Electrocardiography; In Vitro Techniques; Isoproterenol; Male; Myocardial Infarction; Myoca

1981
[Determination of tissue creatine phosphokinase as a direct enzymatic method for evaluation of the area of necrosis in rats with isoproterenol-induced infarctions].
    Minerva cardioangiologica, 1981, Volume: 29, Issue:11

    Topics: Animals; Creatine Kinase; Isoproterenol; Myocardial Infarction; Myocardium; Necrosis; Rats; Rats, In

1981
The influence of long-term application of isoproterenol on the results of temporary ischemia of the rat heart muscle.
    Experimental pathology, 1981, Volume: 20, Issue:3

    Topics: Adaptation, Physiological; Animals; Coronary Disease; Female; Isoproterenol; Myocardium; Necrosis; O

1981
[Vitamin E (tocopherol) levels in the blood serum and myocardium of rats with myocardial micronecrosis caused by stimulation with isoprenaline].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1980, Jan-14, Volume: 35, Issue:2

    Topics: Animals; Cardiomyopathies; Isoproterenol; Male; Muscular Atrophy; Myocardium; Necrosis; Rats; Stimul

1980
[Urea synthesis in the myocardium].
    Biulleten' eksperimental'noi biologii i meditsiny, 1980, Volume: 89, Issue:2

    Topics: Amino Acids; Ammonia; Animals; Heart; In Vitro Techniques; Isoproterenol; Male; Myocardium; Necrosis

1980
[Neutralization of ammonia in cardiac muscle].
    Biulleten' eksperimental'noi biologii i meditsiny, 1980, Volume: 89, Issue:3

    Topics: Alanine; Ammonia; Animals; Aspartic Acid; Cardiomyopathies; Glutamates; Glutamine; Isoproterenol; Ma

1980
[Histometric characteristics of capillary-glio-neurocytic relationships of cervicothoracic (stellate) ganglia of cats during experimental isadrine-induced myocardial necrosis].
    Biulleten' eksperimental'noi biologii i meditsiny, 1980, Volume: 89, Issue:5

    Topics: Animals; Capillaries; Cardiomyopathies; Cats; Isoproterenol; Necrosis; Neuroglia; Stellate Ganglion

1980
The action of flunarizine and lidoflazine on isoprenaline induced cardiac lesions.
    Archives internationales de pharmacodynamie et de therapie, 1980, Volume: 244, Issue:2

    Topics: Animals; Cinnarizine; Drug Antagonism; Female; Flunarizine; Heart; Isoproterenol; Lidoflazine; Myoca

1980
Isoproterenol-induced myocardial necrosis and membrane permeability alterations in the isolated perfused rabbit heart.
    Experimental and molecular pathology, 1980, Volume: 33, Issue:1

    Topics: Animals; Cell Membrane Permeability; Heart; Heart Rate; Horseradish Peroxidase; Isoproterenol; Male;

1980
Hypoxic tolerance of rats with isoproterenol-induced myocardial necrosis.
    Advances in myocardiology, 1980, Volume: 2

    Topics: Adrenalectomy; Animals; Atmosphere Exposure Chambers; Heart; Hydrocortisone; Hypoxia; Isoproterenol;

1980
Effect of phenelzine, a monoamine oxidase inhibitor, on isoproterenol-induced myocardial damage.
    Advances in myocardiology, 1980, Volume: 2

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Heart; Isoproterenol; Male; Myocardial I

1980
Effect of extent of myocardial damage on the behavior of myocardial zinc in albino rats.
    Advances in myocardiology, 1980, Volume: 2

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Heart; Isoproterenol; L-Lactate Dehydrog

1980
[Comparative study using colloidal lanthanum of defects in cardiomyocyte membrane permeability in deep ischemia and in isoproterenol exposure].
    Arkhiv patologii, 1980, Volume: 42, Issue:10

    Topics: Animals; Cell Membrane Permeability; Colloids; Coronary Disease; Dogs; Isoproterenol; Lanthanum; Mic

1980
Studies of hypotension and cardiac flow in isoproterenol-induced myocardial necrosis.
    Experimental and molecular pathology, 1981, Volume: 34, Issue:1

    Topics: Animals; Calcium; Cardiomyopathies; Coronary Circulation; Heart; Hypotension; Isoproterenol; Male; M

1981
Isoproterenol-induced redistribution of endosomes in cardiac myocytes.
    European journal of cell biology, 1994, Volume: 65, Issue:1

    Topics: Animals; Cells, Cultured; Endosomes; Frozen Sections; Heart; Hydrogen-Ion Concentration; Immunohisto

1994
The myocardial effects of fenoterol, isoprenaline and salbutamol in normoxic and hypoxic sheep.
    International journal of experimental pathology, 1994, Volume: 75, Issue:5

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Female; Fenoterol; Heart; Heart Rate; Hypokalemia; Hyp

1994
Progressive ventricular remodeling in response to diffuse isoproterenol-induced myocardial necrosis in rats.
    Circulation research, 1994, Volume: 75, Issue:1

    Topics: Animals; Blood Pressure; Blood Volume; Diastole; Heart; Hemodynamics; Isoproterenol; Male; Myocardiu

1994
[The effect of the antioxidant, butylhydroxyanisole on experimental myocardial necrosis in rats. Morphologic study].
    Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti, 1994, Volume: 43, Issue:3

    Topics: Animals; Butylated Hydroxyanisole; Heart; Isoproterenol; Male; Myocardium; Necrosis; Rats; Rats, Wis

1994
Effect of policosanol on isoprenaline-induced myocardial necrosis in rats.
    The Journal of pharmacy and pharmacology, 1994, Volume: 46, Issue:4

    Topics: Administration, Oral; Animals; Aspirin; Fatty Alcohols; Glycosaminoglycans; Heart; Isoproterenol; Ma

1994
DNA resynthesis and binucleated metamorphosis in cardiac muscle cells after isoproterenol-induced injury: bromodeoxyuridine immunohistochemistry.
    The American journal of cardiovascular pathology, 1995, Volume: 5, Issue:1

    Topics: Animals; Bromodeoxyuridine; Cardiomyopathies; Cardiotonic Agents; Cell Nucleus; DNA; Immunohistochem

1995
Effect of left ventricular sphericity on the evolution of ventricular dysfunction in rats with diffuse isoproterenol-induced myocardial necrosis.
    Journal of cardiac failure, 1998, Volume: 4, Issue:1

    Topics: Adrenergic beta-Agonists; Analysis of Variance; Animals; Cardiac Output; Cardiomyopathies; Disease M

1998
Effect of a novel tetrapeptide derivative in a model of isoproterenol induced myocardial necrosis.
    Molecular and cellular biochemistry, 1998, Volume: 187, Issue:1-2

    Topics: Adrenergic beta-Agonists; Animals; Aspirin; Body Weight; Creatine Kinase; Disease Models, Animal; Fe

1998
Collagen profile in isoproterenol induced myocardial necrosis in rats.
    Indian journal of experimental biology, 1998, Volume: 36, Issue:8

    Topics: Animals; Collagen; Female; Heart; Isoproterenol; Myocardium; Necrosis; Rats; Rats, Wistar

1998
Curcumin treatment modulates collagen metabolism in isoproterenol induced myocardial necrosis in rats.
    Molecular and cellular biochemistry, 1999, Volume: 197, Issue:1-2

    Topics: Animals; Body Weight; Cell Division; Collagen; Curcumin; DNA; DNA Replication; Female; Heart; Hydrox

1999
Cardiomyocyte apoptosis contributes to the development of catacholamine cardiomyopathy.
    Clinica chimica acta; international journal of clinical chemistry, 2001, Volume: 308, Issue:1-2

    Topics: Animals; Apoptosis; Biomarkers; Cardiomyopathies; Isoproterenol; Macrophages; Myocardium; Necrosis;

2001
Experimental myocardial necrosis in rats: role of arjunolic acid on platelet aggregation, coagulation and antioxidant status.
    Molecular and cellular biochemistry, 2001, Volume: 224, Issue:1-2

    Topics: Animals; Antioxidants; Aspirin; Blood Coagulation; Electrocardiography; Female; Humans; Hydrogen Per

2001
Cardioprotective potential of ocimum sanctum in isoproterenol induced myocardial infarction in rats.
    Molecular and cellular biochemistry, 2001, Volume: 225, Issue:1-

    Topics: Animals; Cardiotonic Agents; Cell Membrane; Dose-Response Relationship, Drug; Female; Glutathione; H

2001
Effect of diabetes mellitus on hemodynamic and cardiometabolic correlates in experimental myocardial infarction.
    Advances in experimental medicine and biology, 2001, Volume: 498

    Topics: Analysis of Variance; Animals; Body Weight; Diabetes Mellitus, Experimental; Disease Models, Animal;

2001
Antioxidant potential of a novel tetrapeptide derivative in isoproterenol-induced myocardial necrosis in rats.
    Pharmacology, 2002, Volume: 65, Issue:2

    Topics: Animals; Antioxidants; Electrocardiography; Female; Heart; Isoproterenol; Lipid Peroxides; Myocardiu

2002
Role of cardiovascular and ionic changes in pathogenesis and prevention of isoprenaline-induced cardiac necrosis.
    Recent advances in studies on cardiac structure and metabolism, 1975, Volume: 6

    Topics: Animals; Blood Pressure; Carbon Dioxide; Cardiomyopathies; Heart Rate; Hydrogen-Ion Concentration; I

1975
Alterations in norepinephrine pattern in the damaged myocardium in the rat.
    Recent advances in studies on cardiac structure and metabolism, 1975, Volume: 6

    Topics: Animals; Cardiomegaly; Cardiomyopathies; Isoproterenol; Male; Monoamine Oxidase; Myocardium; Necrosi

1975
Prevention of myocardial Ca overload and necrotization by Mg and K salts or acidosis.
    Recent advances in studies on cardiac structure and metabolism, 1975, Volume: 6

    Topics: Adenosine Triphosphate; Animals; Calcium; Cardiomyopathies; Dose-Response Relationship, Drug; Hydrog

1975
Effects of metabolic and pharmacologic interventions on myocardial infarct size following coronary occlusion.
    Acta medica Scandinavica. Supplementum, 1976, Volume: 587

    Topics: Acute Disease; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Assisted Circulation

1976
Quantification of changes in enzyme activity induced by drug action.
    The Histochemical journal, 1976, Volume: 8, Issue:4

    Topics: Animals; Formazans; Histocytochemistry; Isoproterenol; Male; Myocardium; Necrosis; Rats; Staining an

1976
Exeriences with isoprenaline induced myocardial necrosis in the rat.
    The Journal of pathology, 1976, Volume: 120, Issue:2

    Topics: Animals; Cats; Heart Diseases; Isoproterenol; Male; Myocardium; Necrosis; Rats; Staining and Labelin

1976
Quantitation of isoprenaline-induced changes in the ventricular myocardium.
    Cardiovascular research, 1975, Volume: 9, Issue:6

    Topics: Animals; Body Weight; Cardiomegaly; Collagen; Dose-Response Relationship, Drug; Heart; Heart Ventric

1975
Induction of necrosis and failure in the isolated perfused rat heart with oxidized isoproterenol.
    Journal of molecular and cellular cardiology, 1975, Volume: 7, Issue:11

    Topics: Animals; Cardiomegaly; Drug Stability; Heart; Heart Diseases; Isoproterenol; Male; Microscopy, Elect

1975
The relationship between fibrosis and lactate dehydrogenase isoenzymes in the experimental hypertrophic heart of rabbits.
    Cardiovascular research, 1978, Volume: 12, Issue:6

    Topics: Animals; Aortic Coarctation; Cardiomegaly; Collagen; Hydroxyproline; Isoenzymes; Isoproterenol; L-La

1978
[Qualitative and quantitative histoenzymatic study on isoproterenol induced myocardial necroses in rats (author's transl)].
    Arzneimittel-Forschung, 1976, Volume: 26, Issue:5

    Topics: Animals; Cardiomyopathies; Disease Models, Animal; Electron Transport Complex IV; Isoproterenol; Mal

1976
[Cardioprotection by oral application of the calcium antagonist fendiline. Prevention of isoproterenol-induced myocardial necroses in rats (author's transl)].
    Arzneimittel-Forschung, 1976, Volume: 26, Issue:10

    Topics: Animals; Calcium; Cardiomyopathies; Electron Transport Complex IV; Isoproterenol; Male; Myocardium;

1976
Adrenocortical function in response to myocardial necrosis in exercise-trained rats.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1978, Volume: 44, Issue:1

    Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aldosterone; Animals; Body Weight; Cardiomyopathies; Co

1978
Isoproterenol induced myocardial necrosis & biogenic amine levels in rats.
    Indian journal of experimental biology, 1979, Volume: 17, Issue:3

    Topics: Animals; Catecholamines; Cyclic AMP; Isoproterenol; Male; Myocardium; Necrosis; Rats

1979
Toxicity of aerosol propellants in the respiratory and circulatory systems. VI. Influence of cardiac and pulmonary vascular lesions in the rat.
    Toxicology, 1975, Volume: 3, Issue:2

    Topics: Adrenal Glands; Adrenalectomy; Adrenergic beta-Antagonists; Aerosol Propellants; Aerosols; Animals;

1975
[How isoproterenol-induced changes in the myocardium of rats are affected by adenosinetriphosphate (author's transl)].
    Casopis lekaru ceskych, 1979, Jan-26, Volume: 118, Issue:4

    Topics: Adenosine Triphosphate; Animals; Drug Interactions; Heart; Isoproterenol; Myocardium; Necrosis; Rats

1979
A temporal profile of changes in myocardial manganese after isoprenaline induced cardiac necrosis in albino rats.
    Archivum immunologiae et therapiae experimentalis, 1979, Volume: 27, Issue:3

    Topics: Animals; Aspartate Aminotransferases; Disease Models, Animal; Electrocardiography; Isoproterenol; L-

1979
The effect of a calcium antagonist (D600) on isoprenaline-induced myocardial necrosis in the rat.
    British journal of experimental pathology, 1979, Volume: 60, Issue:3

    Topics: Animals; Calcium; Cardiomyopathies; Gallopamil; Isoproterenol; Male; Myocardium; Necrosis; Rats; Ver

1979
On significance of plasma fibrinogen level to assess severity of myocardial damage--an experimental study.
    Indian journal of experimental biology, 1979, Volume: 17, Issue:6

    Topics: Animals; Cardiomyopathies; Female; Fibrinogen; Isoproterenol; Male; Myocardial Infarction; Myocardiu

1979
Quantitation of isoproterenol-induced myocardial necrosis with 3H-tetracycline.
    Research communications in chemical pathology and pharmacology, 1979, Volume: 25, Issue:3

    Topics: Animals; Cardiomyopathies; Dose-Response Relationship, Drug; Isoproterenol; Male; Myocardium; Necros

1979
An experimental investigation to correlate changes in plasma fibrinolytic activity with isoprenaline induced myocardial damage.
    Journal of postgraduate medicine, 1979, Volume: 25, Issue:3

    Topics: Animals; Blood Coagulation Tests; Cardiomyopathies; Female; Fibrinolysis; Heart; Isoproterenol; Male

1979
The prevention by creatinol O-phosphate of myocardial lesions evoked by isoprenaline.
    Archives internationales de pharmacodynamie et de therapie, 1979, Volume: 237, Issue:2

    Topics: Animals; Cardiomyopathies; Creatine; Female; Ions; Isoproterenol; Myocardium; Necrosis; Rats; Time F

1979
An analysis of the reduction by creatinol O-phosphate of the myocardial lesions evoked by isoprenaline in the rat.
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:9a

    Topics: Animals; Cardiomyopathies; Coronary Circulation; Creatine; Isoproterenol; Male; Microcirculation; My

1979
[Permant isoproterenol application from an intraperitoneal depot capsule--effects on the heart].
    Experimentelle Pathologie, 1977, Volume: 14, Issue:5

    Topics: Animals; Aspartate Aminotransferases; Delayed-Action Preparations; Drug Implants; Female; Heart; Hea

1977
Pathogenesis of isoproterenol-induced myocardial lesions: its reation to human 'coagulative myocytolysis'.
    Cardiology, 1978, Volume: 63, Issue:3

    Topics: Animals; Autoradiography; Histocytochemistry; Humans; Isoproterenol; Microscopy, Electron; Myocardia

1978
A temporal profile of myocardial zinc changes after isoproterenol induced cardiac necrosis.
    Japanese circulation journal, 1978, Volume: 42, Issue:3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Electrocardiography; Heart; Isoprotereno

1978
Isoprenaline-induced myocardial necrosis in dogs.
    British journal of experimental pathology, 1978, Volume: 59, Issue:2

    Topics: Animals; Dogs; Electrocardiography; Enzymes; Female; Heart Diseases; Isoproterenol; Male; Myocardium

1978
[Myocardial lesions caused by catecholamines (isoproterenol). Study with optical and electronic microscopy].
    Revista espanola de cardiologia, 1978, Volume: 31, Issue:1 Pt 2

    Topics: Animals; Humans; Isoproterenol; Microscopy, Electron; Mitochondria, Heart; Myocardial Infarction; Ne

1978
Protective effects of clofibrate on isoproterenol-induced myocardial infarction in arteriosclerotic and non-arteriosclerotic rats.
    Atherosclerosis, 1978, Volume: 29, Issue:3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Glucose; Blood Urea Nitrogen; Clof

1978
Subcutaneous isoproterenol: a convenient rat model for early detection of myocardial necrosis.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1978, Volume: 19, Issue:8

    Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Radiation; Isoproterenol; Myocardial In

1978
Experimental catecholamine-induced acute myocardial necrosis.
    Advances in cardiology, 1978, Volume: 25

    Topics: Acute Disease; Animals; Catecholamines; Dogs; Heart; Hemodynamics; Infusions, Parenteral; Isoprotere

1978
Effects of pharmacological intervention on infarct size following induced myocardial infarction in rats.
    Journal of pharmaceutical sciences, 1978, Volume: 67, Issue:11

    Topics: Animals; Creatine Kinase; Hyaluronoglucosaminidase; Insulin; Isoproterenol; Male; Myocardial Infarct

1978
A temporal profile of changes in myocardial copper after isoproterenol induced cardiac necrosis.
    Japanese circulation journal, 1978, Volume: 42, Issue:6

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cardiomyopathies; Copper; Electrocardiog

1978
[Prevention of the myocardial damaging effect of isadrin by curantil].
    Biulleten' eksperimental'noi biologii i meditsiny, 1978, Volume: 86, Issue:11

    Topics: Animals; Coronary Disease; Dipyridamole; Electrocardiography; Female; Isoproterenol; Male; Myocardia

1978
[Adaptation of the rat myocardium to long-time application of small doses of isoproterenol (author's transl)].
    Experimentelle Pathologie, 1978, Volume: 16, Issue:1-6

    Topics: Adaptation, Physiological; Animals; Drug Administration Schedule; Heart; Isoproterenol; Male; Myocar

1978
[Modification of isoprenaline-induced myocardial necrosis in the rat by means of pre-treatment with cerutil and piracetam].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1976, Aug-01, Volume: 31, Issue:15

    Topics: Animals; Coronary Disease; Disease Models, Animal; Glycolates; Heart; Isoproterenol; Male; Meclofeno

1976
[Microscopic quantification of myocardial necroses in experimental cardiology].
    Acta histochemica. Supplementband, 1976, Volume: 16

    Topics: Animals; Calcitonin; Dose-Response Relationship, Drug; Gallopamil; Histological Techniques; Isoprote

1976
The effect of anti-lipolytic agents on isoprenaline-induced myocardial necrosis in the rat.
    British journal of experimental pathology, 1977, Volume: 58, Issue:4

    Topics: Animals; Fatty Acids, Nonesterified; Fever; Heart Diseases; Isoproterenol; Male; Myocardium; Necrosi

1977
[Quantitative evaluation of histochemical examinations of the protective effect of KMg-aspartate upon necroses of the myocardium experimentally induced by isoproterenol (author's transl)].
    Bratislavske lekarske listy, 1976, Volume: 65, Issue:3

    Topics: Animals; Aspartic Acid; Cardiomyopathies; Disease Models, Animal; Dogs; Isoproterenol; Magnesium; Ne

1976
The action of isoproterenol on the chick embryo heart.
    Journal of molecular and cellular cardiology, 1976, Volume: 8, Issue:7

    Topics: Age Factors; Animals; Body Weight; Chick Embryo; Coronary Vessels; Heart; Heart Defects, Congenital;

1976
On the pathogenesis of cardiac necroses induced by theophylline and caffeine.
    Acta pharmacologica et toxicologica, 1976, Volume: 39, Issue:3

    Topics: Animals; Blood Pressure; Caffeine; Calcium; Gallopamil; Heart; Heart Rate; Isoproterenol; Male; Myoc

1976
[Modification of the isoprenaline-induced myocardial necrosis using trapidil].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1976, Sep-15, Volume: 31, Issue:18

    Topics: Animals; Cardiomyopathies; Disease Models, Animal; Isoproterenol; Male; Myocardial Infarction; Necro

1976
Isoprenaline-induced changes in regional myocardial perfusion in the pathogenesis of myocardial necrosis.
    British journal of experimental pathology, 1976, Volume: 57, Issue:6

    Topics: Animals; Coronary Circulation; Dose-Response Relationship, Drug; Isoproterenol; Male; Myocardial Inf

1976
Chemical and morphological studies of rat myocardium after application of a necrogenic dose of isoproterenol.
    Experimentelle Pathologie, 1976, Volume: 12, Issue:6

    Topics: Animals; Isoproterenol; Male; Myocardium; Necrosis; Potassium; Rats; Sodium; Time Factors

1976
Influencing heart necroses caused by application of isoproterenol, potassium orotat.
    Scripta medica, 1976, Volume: 49, Issue:6-7

    Topics: Animals; Female; Heart Diseases; Isoproterenol; Male; Necrosis; Orotic Acid; Rats

1976
The role of myocardial membrane lipids in the development of cardiac necrosis.
    Acta medica Scandinavica. Supplementum, 1976, Volume: 587

    Topics: Adenosine Triphosphate; Age Factors; Animals; Arachidonic Acids; Dietary Fats; Energy Metabolism; Fa

1976
[Key-role of intracellular calcium overload in acute necrosis of the myocardium. Cardioprotection with verapamil].
    Minerva medica, 1975, May-23, Volume: 66, Issue:38

    Topics: Adenosine Triphosphate; Animals; Calcium; Catecholamines; Dihydrotachysterol; Fludrocortisone; Heart

1975
Isoprenaline-induced cardiac necroses in normotensive and in spontaneously hypertensive rats.
    Acta medica Iugoslavica, 1975, Volume: 29, Issue:3

    Topics: Animals; Disease Models, Animal; Electrocardiography; Female; Heart Diseases; Hypertension; Isoprote

1975
Effects of hormonal pretreatment of cardiac necrosis in the Japanese quail.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1975, Volume: 149, Issue:2

    Topics: Animals; Castration; Coturnix; Estradiol; Female; Hematocrit; Isoproterenol; Male; Myocardial Infarc

1975
Morphological changes after simultaneous administration of isoproterenol (ISO) and K+,MG2+-Aspartate (KMg-ASP) as a physiological Ca2+ antagonist.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:6

    Topics: Animals; Aspartic Acid; Calcium; Dogs; Extracellular Space; Glycogen; Histocytochemistry; Isoprotere

1975
Experimental cardiac necrosis in hypobaric and anemic hypoxia.
    Journal of applied physiology, 1975, Volume: 39, Issue:2

    Topics: Anemia, Hypochromic; Animals; Atmosphere Exposure Chambers; Hemoglobins; Hypoxia; Injections, Subcut

1975
[Influencing myocardial necroses induced by isoproterenol, the physiologic antagonist of calcium, in experiments (author's transl)].
    Bratislavske lekarske listy, 1975, Volume: 64, Issue:4

    Topics: Animals; Aspartic Acid; Calcium; Dogs; Isoproterenol; Male; Myocardial Infarction; Myocardium; Necro

1975
Restriction of isoproterenol-induced myocardial Ca uptake and necrotization in rats by a new Ca-antagonistic compound (ethyl-4-(3,4,5-trimethoxycinnamoyl) piperazinyl acetate (Vascordil)).
    Recent advances in studies on cardiac structure and metabolism, 1975, Volume: 6

    Topics: Animals; Biological Transport; Calcium; Cardiomyopathies; Cinnamates; Dose-Response Relationship, Dr

1975
Myocardial metabolism at different environmental temperatures in experimental myocardial necrosis.
    Recent advances in studies on cardiac structure and metabolism, 1975, Volume: 6

    Topics: Adrenal Glands; Alanine Transaminase; Animals; Ascorbic Acid; Aspartate Aminotransferases; Cardiomyo

1975
Role of free fatty acids in catecholamine-induced cardiac necrosis.
    Recent advances in studies on cardiac structure and metabolism, 1975, Volume: 6

    Topics: Animals; Blood Pressure; Creatine Kinase; Fatty Acids, Nonesterified; Female; Heart Rate; Isoprotere

1975
Changes in fatty acid composition of cardiac lipids accompanying myocardial necrosis.
    Recent advances in studies on cardiac structure and metabolism, 1975, Volume: 6

    Topics: Animals; Cardiomyopathies; Cod Liver Oil; Fatty Acids; Fatty Acids, Unsaturated; Isoproterenol; Lipi

1975
Key role of Ca in the production of noncoronarogenic myocardial necroses.
    Recent advances in studies on cardiac structure and metabolism, 1975, Volume: 6

    Topics: Adenosine Triphosphate; Animals; Calcium; Cardiomyopathies; Heart; Humans; Isoproterenol; Muscles; N

1975
Isoproterenol-induced necrotic lesions of embryonic heart tissue.
    Recent advances in studies on cardiac structure and metabolism, 1975, Volume: 6

    Topics: Animals; Chick Embryo; Gestational Age; Heart; Isoproterenol; Myocardium; Necrosis

1975
Cardiotoxicity of intravenous isoproterenol in rats.
    The Indian journal of medical research, 1975, Volume: 63, Issue:1

    Topics: Adrenal Medulla; Animals; Female; Heart; Infusions, Parenteral; Isoproterenol; Male; Myocardium; Nec

1975
[Myocardial DNA and cell count following isoproterenol-induced myocardial necrosis in the rat].
    Verhandlungen der Deutschen Gesellschaft fur Pathologie, 1975, Volume: 59

    Topics: Animals; Cardiomyopathies; Cell Count; DNA; Female; Heart; Isoproterenol; Myocardium; Necrosis; Rats

1975
[Isoproterenol-induced changes of autoradiographic 45 Ca-distribution in the myocardium. Inhibition by Ca-antagonists].
    Verhandlungen der Anatomischen Gesellschaft, 1975, Volume: 69

    Topics: Animals; Autoradiography; Calcium; Calcium Radioisotopes; Cardiomyopathies; Heart; Isoproterenol; My

1975
beta Adrenergic receptor desensitisation may serve a cardioprotective role.
    Cardiovascular research, 1992, Volume: 26, Issue:6

    Topics: Adrenergic beta-Antagonists; Animals; Heart; Heart Diseases; Hypothyroidism; Infusion Pumps; Injecti

1992
Isoproterenol fails to produce myocardial necrosis in streptozotocin-induced diabetic rats.
    Indian journal of experimental biology, 1991, Volume: 29, Issue:9

    Topics: Animals; Diabetes Mellitus, Experimental; Heart; Isoproterenol; Male; Myocardium; Necrosis; Rats; Ra

1991
Potentiation of carbon tetrachloride hepatotoxicity by phenylpropanolamine.
    Toxicology and applied pharmacology, 1991, Volume: 111, Issue:2

    Topics: Animals; Body Temperature; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Clonidine;

1991
Cardiotoxicity of hydralazine and minoxidil in the rat. Influence of age.
    Research communications in chemical pathology and pharmacology, 1991, Volume: 71, Issue:2

    Topics: Aging; Animals; Blood Pressure; Heart Diseases; Heart Rate; Hydralazine; Isoproterenol; Minoxidil; M

1991
[Distribution of fatty acids in the myocardium in rabbits during the development of isoprenaline necrosis].
    Ceskoslovenska fysiologie, 1990, Volume: 39, Issue:6

    Topics: Animals; Fatty Acids; Heart; Isoproterenol; Myocardium; Necrosis; Rabbits

1990
Effect of nitroglycerin and a nitroglycerin-like substance in isoprenaline (ISO) necrosis and hypoxia.
    Acta physiologica Hungarica, 1990, Volume: 75 Suppl

    Topics: Animals; Hypoxia; Isoproterenol; Molsidomine; Necrosis; Nitroglycerin; Rats

1990
[Effect of celiprolol on isoprenaline-induced myocardial necrosis].
    Casopis lekaru ceskych, 1990, Apr-06, Volume: 129, Issue:14

    Topics: Animals; Celiprolol; Heart; Humans; Isoproterenol; Male; Myocardium; Necrosis; Propanolamines; Rats;

1990
Isoproterenol-induced myocardial fibrosis in relation to myocyte necrosis.
    Circulation research, 1989, Volume: 65, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Autoradiography; Cardiomegaly; DNA; DNA Replication; Fibrosis; Hear

1989
Connective tissue cells in healing rat myocardium. A study of cell reactions in rhythmically contracting environment.
    The American journal of pathology, 1989, Volume: 134, Issue:5

    Topics: Animals; Connective Tissue; Coronary Disease; Female; Freezing; Heart; Isoproterenol; Male; Myocardi

1989
Increased sarcolemmal membrane permeability of cardiac muscle cells in rats fed grains cultivated in a Keshan disease endemic area: a study with horseradish peroxidase as a tracer.
    Experimental and molecular pathology, 1989, Volume: 50, Issue:3

    Topics: Animals; Cardiomyopathy, Dilated; Cell Membrane Permeability; Diet; Edible Grain; Horseradish Peroxi

1989
Protection against isoproterenol-induced myocardial necrosis in rats by 6-mercaptopurine and 6-thioguanine or by irradiation.
    Research communications in chemical pathology and pharmacology, 1989, Volume: 63, Issue:3

    Topics: Allopurinol; Animals; Heart Diseases; Isoproterenol; Leukocytes; Leukopenia; Male; Mercaptopurine; M

1989
A morphometrical method to estimate isoproterenol-induced infarct size in the rat.
    Methods and findings in experimental and clinical pharmacology, 1989, Volume: 11, Issue:5

    Topics: Animals; Female; Isoproterenol; Myocardial Infarction; Myocardium; Necrosis; Nitroblue Tetrazolium;

1989
Ultrastructure of isoproterenol-induced myocardial damage in chick embryos.
    Physiologia Bohemoslovaca, 1985, Volume: 34, Issue:4

    Topics: Animals; Chick Embryo; Heart; Isoproterenol; Microscopy, Electron; Myocardium; Necrosis; Time Factor

1985
Increase and regression of the protective effect of high altitude acclimatization on the isoprenaline-induced necrotic lesions in the rat myocardium.
    Physiologia Bohemoslovaca, 1987, Volume: 36, Issue:1

    Topics: Acclimatization; Adipose Tissue; Altitude; Animals; Body Weight; Drug Resistance; Eating; Heart; Hyp

1987
Quantification of myocardial necrosis and cardiac hypertrophy in isoproterenol-treated rats.
    Research communications in chemical pathology and pharmacology, 1987, Volume: 57, Issue:1

    Topics: Animals; Aspartate Aminotransferases; Cardiomegaly; Cardiomyopathies; Creatine Kinase; DNA; Isoprote

1987
Influence of the diabetic state on isoproterenol-induced cardiac necrosis.
    Journal of molecular and cellular cardiology, 1985, Volume: 17, Issue:4

    Topics: Animals; Cardiomyopathies; Cyclic AMP; Diabetes Mellitus, Experimental; Heart; Insulin; Isoprotereno

1985
Protective effect of the new calcium antagonist anipamil against isoprenaline-induced cardionecrosis in rats.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:2

    Topics: Acid Phosphatase; Animals; Calcium Channel Blockers; Cardiomyopathies; Glucosephosphate Dehydrogenas

1988
Catecholamine-induced necrosis and hypertrophy. Hemodynamic factors.
    Advances in myocardiology, 1985, Volume: 6

    Topics: Animals; Blood Pressure; Cardiomegaly; Catecholamines; Dobutamine; Dopamine; Heart Rate; Heart Ventr

1985
Alterations in isoproterenol-induced cardiac metabolic changes by a quaternary analog of propranolol, UM-272.
    Acta cardiologica, 1985, Volume: 40, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Creatine Kinase; Dose-Response Relationship, Drug; Energy Metabolis

1985
The evaluation of HBDH and LDH isoenzymes in cardiac cell necrosis of the rat.
    Journal of applied toxicology : JAT, 1988, Volume: 8, Issue:4

    Topics: Animals; Female; Heart; Humans; Hydroxybutyrate Dehydrogenase; Isoenzymes; Isoproterenol; L-Lactate

1988
Heart lactate dehydrogenase isoenzymes as a function of age, exercise and experimental necrosis.
    Indian journal of experimental biology, 1988, Volume: 26, Issue:8

    Topics: Aging; Animals; Isoenzymes; Isoproterenol; L-Lactate Dehydrogenase; Myocardium; Necrosis; Physical C

1988
The protective effect of Allium sativum and crataegus on isoprenaline-induced tissue necroses in rats.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:11

    Topics: Acid Phosphatase; Animals; Garlic; Glucosephosphate Dehydrogenase; Histocytochemistry; Isoproterenol

1988
Cardioprotective effect of prostacyclin and 7-oxo-PGI2 in rats against chronic isoproterenol damage.
    Prostaglandins, 1987, Volume: 33, Issue:4

    Topics: Animals; Epoprostenol; Heart; Isoproterenol; Male; Myocardial Infarction; Myocardium; Necrosis; Rats

1987
Basal lamina of rat myocardium. Its fate after death of cardiac myocytes.
    Laboratory investigation; a journal of technical methods and pathology, 1988, Volume: 58, Issue:1

    Topics: Animals; Basement Membrane; Cell Survival; Cicatrix; Coronary Disease; Freezing; Isoproterenol; Myoc

1988
Myocyte reactions at the borders of injured and healing rat myocardium.
    Laboratory investigation; a journal of technical methods and pathology, 1988, Volume: 59, Issue:1

    Topics: Animals; Basement Membrane; Coronary Disease; Female; Freezing; Heart; Isoproterenol; Male; Microsco

1988
Neurohormonal regulation of calcium in the cell.
    Neurochemical research, 1988, Volume: 13, Issue:5

    Topics: Animals; Brain; Calcium; Hypothalamic Hormones; Isoproterenol; Mitochondria, Heart; Molecular Weight

1988
The effect of cordarone on isoproterenol-induced damage to the myocardium in rats.
    Experimental pathology, 1986, Volume: 29, Issue:4

    Topics: Amiodarone; Animals; Benzofurans; Cardiomyopathies; Isoproterenol; Male; Necrosis; Rats; Rats, Inbre

1986
Isoproterenol induced myocardial necrosis is associated with stress protein synthesis in rat heart and thoracic aorta.
    Cardiovascular research, 1986, Volume: 20, Issue:7

    Topics: Animals; Aorta, Thoracic; Heart; Heat-Shock Proteins; Isoproterenol; Male; Myocardium; Necrosis; Rat

1986
Sodium nitrite protects against isoproterenol-induced myocardial necrosis.
    Journal of molecular and cellular cardiology, 1986, Volume: 18, Issue:10

    Topics: Animals; Drug Interactions; Female; Heart; Isoproterenol; Male; Myocardium; Necrosis; Nitrites; Rats

1986
[Changes in the population of mitochondria in a model of myocardial cell damage].
    Bratislavske lekarske listy, 1987, Volume: 87, Issue:1

    Topics: Animals; Coronary Disease; Female; Isoproterenol; Mitochondria, Heart; Myocardium; Necrosis; Pregnan

1987
[Effect of enkephalins on the course of experimental izadrin-induced myocardial necrosis in the rabbit].
    Kardiologiia, 1985, Volume: 25, Issue:12

    Topics: Animals; Cardiomyopathies; Creatine Kinase; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Isoe

1985
Myocardial ultrastructural alterations in ducklings with isoproterenol-induced cardiotoxicosis.
    American journal of veterinary research, 1986, Volume: 47, Issue:2

    Topics: Animals; Cardiomyopathies; Ducks; Isoproterenol; Male; Microscopy, Electron; Myocardium; Necrosis

1986
[Prophylactic effect of coenzyme Q10 on isoproterenol-induced myocardial necrosis in rats].
    Zhonghua xin xue guan bing za zhi, 1985, Volume: 13, Issue:1

    Topics: Animals; Cardiomyopathies; Coenzymes; Female; Isoproterenol; Male; Mitochondria, Heart; Myocardium;

1985
Essential contribution of thrombocytes to the occurrence of catecholamine-induced cardiac necroses.
    Journal of molecular and cellular cardiology, 1985, Volume: 17, Issue:4

    Topics: Animals; Blood Platelets; Cardiomyopathies; Catecholamines; Female; Isoproterenol; Microcirculation;

1985
Effect of repeated isoproterenol administration in young rats. A histological and serological study.
    Pathologia et microbiologia, 1970, Volume: 36, Issue:2

    Topics: Animals; Autoantibodies; Electron Transport Complex IV; Female; Fibroblasts; Heart; Hemagglutination

1970
Acute myocardial histopathology in normal and arteriosclerotic rats during isoproterenol-induced infarction.
    British journal of experimental pathology, 1970, Volume: 51, Issue:6

    Topics: Acidosis; Animals; Arteriosclerosis; Female; Hypoxia; Isoproterenol; Male; Myocardial Infarction; My

1970
Biochemical changes of myocardial necrosis induced by isoproterenol and protective effects of beta-blocker and anti-inflammatory drugs.
    Chemical & pharmaceutical bulletin, 1974, Volume: 22, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents; Blood Pressure; Heart Diseases; Hear

1974
The effect of isoprenaline pretreatment on the size of acute myocardial necrosis induced by the same drug.
    Physiologia Bohemoslovaca, 1966, Volume: 15, Issue:4

    Topics: Animals; Drug Tolerance; Heart; Isoproterenol; Male; Necrosis; Rats

1966
Estimation of grossly detectable isoproterenol-induced myocardiopathies in rats using the ridit transformation.
    Toxicology and applied pharmacology, 1966, Volume: 9, Issue:2

    Topics: Animals; Cardiomegaly; Cardiomyopathies; Female; Isoproterenol; Necrosis; Organ Size; Rats; Statisti

1966
Myocardial connective tissue metabolism in response to injury. Histological and chemical studies of mucopolysaccharide and collagen in rat hearts after isoproterenol-induced infaraction.
    Circulation research, 1969, Volume: 25, Issue:2

    Topics: Animals; Arteriosclerosis; Cicatrix; Collagen; Connective Tissue; Female; Glycosaminoglycans; Hexosa

1969
Myocardial connective tissue metabolism in response to injury. II. Investigation of the mucopolysaccharides involved in isoproterenol-induced necrosis and repair in rat hearts.
    Circulation research, 1970, Volume: 26, Issue:1

    Topics: Amino Sugars; Animals; Chondroitin; Cicatrix; Connective Tissue; Edema; Glycoproteins; Glycosaminogl

1970
Shift in the lactate dehydrogenase isoenzyme spectrum in isoproterenol-induced acute experimental cardiac necrosis in the rat.
    Physiologia Bohemoslovaca, 1970, Volume: 19, Issue:3

    Topics: Animals; Electrophoresis; Female; Heart Diseases; Isoenzymes; Isoproterenol; L-Lactate Dehydrogenase

1970
Effect of age, body weight and body fat on experimental myocardial necrosis.
    Physiologia Bohemoslovaca, 1970, Volume: 19, Issue:4

    Topics: Adipose Tissue; Age Factors; Analysis of Variance; Animals; Body Weight; Heart Diseases; Isoproteren

1970
Experimental cardiomegalies and "cardiomegalies" in free-living animals.
    Annals of the New York Academy of Sciences, 1969, Jan-31, Volume: 156, Issue:1

    Topics: Animals; Birds; Body Weight; Cardiomegaly; Coronary Vessels; Fishes; Heart; Heart Diseases; Isoprote

1969
Effect of necrogenic doses of isoproterenol on the heart of the tench (Tinca tinca--osteoichthyes), the frog (Rana temporaria--anura) and the pigeon (Columba livia--aves).
    Physiologia Bohemoslovaca, 1971, Volume: 20, Issue:6

    Topics: Animals; Anura; Coloring Agents; Columbidae; Coronary Vessels; Endoplasmic Reticulum; Fishes; Heart

1971
Extrafocal changes in experimental myocardial necroses of rats.
    Physiologia Bohemoslovaca, 1971, Volume: 20, Issue:6

    Topics: Animals; Coronary Vessels; Heart; Histological Techniques; Isoproterenol; Ligation; Male; Microscopy

1971
Comparison of histological findings in subendocardial layer of rat myocardium after ligature of coronary artery and isoproterenol administration.
    Physiologia Bohemoslovaca, 1971, Volume: 20, Issue:6

    Topics: Animals; Coronary Vessels; Heart; Histological Techniques; Isoproterenol; Ligation; Microscopy, Pola

1971
[Influencing of the isoprenaline necrosis of the myocardium by ATP-Spofa administration].
    Ceskoslovenska patologie, 1971, Volume: 7, Issue:2

    Topics: Adenosine Triphosphate; Animals; Cardiomegaly; Disease Models, Animal; Female; Heart; Isoproterenol;

1971
[Cardiac hypertrophy induced by isoproterenol (morphometric, electron-microscopic, autoradiographic, cytophotometric and biochemical findings)].
    Virchows Archiv. B, Cell pathology, 1972, Volume: 12, Issue:1

    Topics: Animals; Autoradiography; Cardiomegaly; Cell Nucleus; Chromatin; DNA; Edema; Glycogen; Histocytochem

1972
Comparative morphological study of some experimental models of myocardial hypertrophy.
    Cor et vasa, 1971, Volume: 13, Issue:4

    Topics: Animals; Aortic Valve Stenosis; Cardiomegaly; Disease Models, Animal; Isoproterenol; Male; Mice; Myo

1971
Proceedings: Changes in myocardial ultrastructure and autoradiographic 45Ca distribution during isoproterenol-induced cardiac necrotization--prevention by Ca-antagonistic compounds.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:Suppl

    Topics: Adrenal Cortex Hormones; Animals; Autoradiography; Calcium; Calcium Radioisotopes; Dihydrotachystero

1974
Myosin aggregation in cardiac necroses induced by isoproterenol in rats.
    Physiologia Bohemoslovaca, 1970, Volume: 19, Issue:1

    Topics: Adenosine Triphosphate; Animals; Chromatography; Electrophoresis; Heart Diseases; Isoproterenol; Mus

1970
[Hemorrhagic necrosis of the digestive tract and heart failure].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1969, Jun-14, Volume: 45, Issue:28

    Topics: Aged; Aorta; Arteriosclerosis; Digestive System; Gastrointestinal Hemorrhage; Heart Failure; Humans;

1969
[The effect of L-aspartic acid in isoproterenol necrosis of cardiac muscle].
    Kardiologiia, 1972, Volume: 12, Issue:12

    Topics: Alanine Transaminase; Amino Acids; Animals; Aspartate Aminotransferases; Aspartic Acid; Heart Diseas

1972
The cardiotoxic effects of pressurized aerosol isoproterenol in the dog.
    Toxicology and applied pharmacology, 1973, Volume: 26, Issue:3

    Topics: Adrenocorticotropic Hormone; Aerosols; Animals; Arrhythmias, Cardiac; Dogs; Electrocardiography; Fem

1973
[The importance of adrenergic beta-receptors for the cardiotoxic action of sympathomimetic amines].
    Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1965, Volume: 13, Issue:3

    Topics: Animals; Bronchodilator Agents; Epinephrine; Ethanolamines; Heart; Heart Diseases; In Vitro Techniqu

1965
Observations on isoprenaline-induced myocardial necroses.
    The Journal of pharmacy and pharmacology, 1967, Volume: 19, Issue:4

    Topics: Animals; Guanethidine; Heart Diseases; Iproniazid; Isoproterenol; Male; Monoamine Oxidase Inhibitors

1967
Competitive antagonism of isoprenaline-induced cardiac necroses by beta-adrenoreceptor blocking agents.
    The Journal of pharmacy and pharmacology, 1969, Volume: 21, Issue:3

    Topics: Animals; Biological Assay; Ethanolamines; Heart Diseases; Injections, Subcutaneous; Isoproterenol; M

1969
[The role of alpha- and beta-receptors in the origin of experimental myocardial necrosis].
    Biulleten' eksperimental'noi biologii i meditsiny, 1967, Volume: 63, Issue:10

    Topics: Animals; Epinephrine; Heart; Isoproterenol; Male; Myocarditis; Necrosis; Norepinephrine; Rats; Senso

1967
The role of cyclic AMP in isoprenaline-induced cardiac necroses in the rat.
    The Journal of pharmacy and pharmacology, 1971, Volume: 23, Issue:3

    Topics: Adenine Nucleotides; Animals; Cyclic AMP; Heart Diseases; Isoproterenol; Male; Myocardium; Necrosis;

1971
Pharmacological studies on heart muscle lesions induced by isoproterenol.
    Annals of the New York Academy of Sciences, 1969, Jan-31, Volume: 156, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amides; Animals; Antihypertensive Agents;

1969
Factors influencing the production of cardiomyopathies by methoxamine and metaraminol.
    Annals of the New York Academy of Sciences, 1969, Jan-31, Volume: 156, Issue:1

    Topics: Adrenalectomy; Adrenergic beta-Antagonists; Animals; Aortic Aneurysm; Blood Pressure; Diet; Edema; F

1969
Fire ant allergy.
    Southern medical journal, 1972, Volume: 65, Issue:3

    Topics: Anaphylaxis; Ants; Child; Emergency Medical Tags; Epinephrine; Female; Histamine H1 Antagonists; Hum

1972
Myocardial necroses produced by intravenous infusion of isoprenaline into rats.
    The Journal of pharmacy and pharmacology, 1971, Volume: 23, Issue:12

    Topics: Alanine Transaminase; Animals; Heart Diseases; Infusions, Parenteral; Injections, Intraperitoneal; I

1971
Progressive electrocardiographic changes in male and female arteriosclerotic and non-arteriosclerotic rats during the course of isoproterenol-induced myocardial infarction.
    Cardiovascular research, 1974, Volume: 8, Issue:4

    Topics: Animals; Arteriosclerosis; Breeding; Electrocardiography; Female; Heart; Heart Rate; Isoproterenol;

1974
Effect of glucose in isoproterenol-induced necrotic heart under anoxic perfusion.
    Japanese journal of pharmacology, 1974, Volume: 24, Issue:5

    Topics: Adenosine Triphosphate; Animals; Glucose; Glycogen; Heart; Heart Diseases; Hypoxia; Isoproterenol; L

1974
[Dynamic follow-up study of the influence of K and Mg asparaginate (Cardilan Spofa) on the development of isoprenaline-induced myocardial necroses in the electron microscopy picture].
    Ceskoslovenska patologie, 1974, Volume: 10, Issue:4

    Topics: Animals; Asparagine; Cardiomyopathies; Disease Models, Animal; Heart; Isoproterenol; Magnesium; Micr

1974
Myocardial fiber necrosis due to intracellular Ca overload-a new principle in cardiac pathophysiology.
    Recent advances in studies on cardiac structure and metabolism, 1974, Volume: 4

    Topics: Ammonium Chloride; Animals; Biological Transport; Calcitonin; Calcium; Cardiomyopathies; Dihydrotach

1974
Isoproterenol myocytolysis and myocardial calcium.
    Recent advances in studies on cardiac structure and metabolism, 1974, Volume: 4

    Topics: Animals; Biological Transport; Calcium; Cardiomyopathies; Dose-Response Relationship, Drug; Isoprote

1974
Successful orthotopic transplantation of the canine liver after prolonged preservation by initial perfusion and cold storage.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1973, Volume: 5, Issue:4

    Topics: Animals; Antifibrinolytic Agents; Azathioprine; Catheterization; Dogs; Graft Rejection; Hemorrhagic

1973
Immunofluorescent studies in isoproterenol-induced myocardial necrosis in rats.
    Experientia, 1974, Apr-15, Volume: 30, Issue:4

    Topics: Animals; Antibodies; Disease Models, Animal; Fluorescent Antibody Technique; Injections, Subcutaneou

1974
[The mechanism of decrease in the cardiotoxic effect of isoprenaline with repeated use].
    Kardiologiia, 1972, Volume: 12, Issue:9

    Topics: Alanine Transaminase; Animals; Drug Tolerance; Heart; Isoproterenol; Male; Myocarditis; Necrosis; Ra

1972
[Effect of K and Mg asparaginate on the structure of isoprenaline-induced myocardial necrosis in the rabbit].
    Ceskoslovenska patologie, 1972, Volume: 8, Issue:4

    Topics: Animals; Asparagine; Heart; Heart Diseases; Isoproterenol; Magnesium; Male; Microscopy, Electron; Ne

1972
Healing of myocardial necrosis caused by sympathomimetic amines.
    Recent advances in studies on cardiac structure and metabolism, 1972, Volume: 1

    Topics: Animals; Calcium; Epinephrine; Heart; Heart Diseases; Isoproterenol; Magnesium; Male; Myocardium; Ne

1972
Myocardial loss of functional magnesium. II. In cardiomyopathies of diverse etiology.
    Recent advances in studies on cardiac structure and metabolism, 1972, Volume: 1

    Topics: Adult; Age Factors; Aging; Animals; Calcium; Cricetinae; Heart; Heart Diseases; Heart Failure; Human

1972
Cardiotoxicity of isoproterenol in experimental animals. Influence of stress, obesity, and repeated dosing.
    Recent advances in studies on cardiac structure and metabolism, 1972, Volume: 1

    Topics: Animals; Dietary Carbohydrates; Dietary Fats; Dogs; Dose-Response Relationship, Drug; Heart; Heart D

1972
Electrocardiography and blood chemistry in the detection of myocardial lesions in dogs.
    Food and cosmetics toxicology, 1973, Volume: 11, Issue:2

    Topics: Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Blood Circulation; Creatine Kinase; Crea

1973
Excitation-contraction coupling in heart. XII. Subcellular calcium transport in isoproterenol-induced myocardial necrosis.
    Experimental and molecular pathology, 1973, Volume: 19, Issue:1

    Topics: Animals; Calcium; Heart Diseases; Hydrogen-Ion Concentration; Isoproterenol; Microsomes; Mitochondri

1973
[Various factors influencing the development of experimental myocardial necrosis].
    Ceskoslovenska fysiologie, 1973, Volume: 22, Issue:1

    Topics: Animals; Cardiomyopathies; Disease Models, Animal; Isoproterenol; Lipid Metabolism; Necrosis; Rats

1973
Changes in myocardial thiamine in arteriosclerotic and non-arteriosclerotic rats subjected to isoprenaline induced myocardial infarction.
    British journal of experimental pathology, 1973, Volume: 54, Issue:5

    Topics: Adrenal Glands; Animals; Arteriosclerosis; Breeding; Female; Isoproterenol; Kidney; Male; Myocardial

1973
Calorigenic effects of isoproterenol during production of myocardial necrosis in the rat.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1973, Oct-01, Volume: 144, Issue:1

    Topics: Animals; Heart Diseases; Isoproterenol; Male; Metabolism; Motor Activity; Muscle Contraction; Myocar

1973
Myocardial necrosis in the rat: a comparison between isoprenaline, orciprenaline, salbutamol and terbutaline.
    Cardiology, 1973, Volume: 58, Issue:3

    Topics: Albuterol; Animals; Cardiomyopathies; Female; Heart; Isoproterenol; Male; Metaproterenol; Myocardium

1973
[Influence of species specificity and age on sensitivity of myocardium following administration of isoprenaline].
    Ceskoslovenska patologie, 1973, Volume: 9, Issue:4

    Topics: Age Factors; Animals; Guinea Pigs; Heart; Isoproterenol; Necrosis; Rabbits; Rats; Species Specificit

1973
[Myocardial changes in intermittently acidified rats following isoprenaline].
    Ceskoslovenska patologie, 1973, Volume: 9, Issue:4

    Topics: Acid-Base Equilibrium; Ammonium Chloride; Animals; Heart; Isoproterenol; Male; Mitochondria; Myocard

1973
Effectiveness of heart muscle extract in myocardial necrosis.
    Indian journal of experimental biology, 1973, Volume: 11, Issue:2

    Topics: Animals; Heart Diseases; Isoproterenol; Male; Myocardium; Necrosis; Rats; Tissue Extracts

1973
Quantitative biochemical changes in rats following isoproterenol-induced myocardial infarction.
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:11

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Blood Proteins; Bl

1973
Ultrastructural changes in isoproterenol-induced atrial necrosis.
    Recent advances in studies on cardiac structure and metabolism, 1973, Volume: 2

    Topics: Animals; Cardiomyopathies; Desoxycorticosterone; Disease Models, Animal; Isoproterenol; Male; Micros

1973
Myocardial glycoprotein changes with isoproterenol-induced necrosis and repair in the rat.
    The American journal of physiology, 1974, Volume: 226, Issue:3

    Topics: Animals; Aspartate Aminotransferases; Glycoproteins; Isoproterenol; Myocardial Infarction; Myocardiu

1974
[Myocardial necrosis induced with isoproterenol in rat heart].
    Acta pharmaceutica Hungarica, 1974, Volume: 44, Issue:1

    Topics: Animals; Carbon Radioisotopes; Heart; Hypoxia; Isoproterenol; Myocardial Infarction; Myocardium; Nec

1974
Simultaneous determination of the capacity of the vascular bed and capillary blood flow in the normal myocardium of the rat and in two types of experimental necrosis.
    Cardiologia, 1968, Volume: 52, Issue:3

    Topics: Animals; Blood Volume; Capillaries; Coronary Vessels; Heart Diseases; Hemostasis; Isoproterenol; Nec

1968
Experimental granulomatous myocarditis: genesis and immunological aspects.
    Annals of the New York Academy of Sciences, 1969, Jan-31, Volume: 156, Issue:1

    Topics: Aged; Animals; Antibody Formation; Antigens; Child, Preschool; Cricetinae; Culture Techniques; Femal

1969
Early alterations of the cardiac muscle cells in isoproterenol-induced necrosis.
    Archives of pathology, 1972, Volume: 93, Issue:4

    Topics: Animals; Heart; Heart Diseases; Isoproterenol; Male; Microscopy, Electron; Mitochondria; Muscles; My

1972
[Effect of Cardilan infusion on the arrhythmic and lethal dose of g-strophantin in a model of experimental isoprenaline necrosis].
    Ceskoslovenska farmacie, 1972, Volume: 21, Issue:4

    Topics: Animals; Arrhythmias, Cardiac; Asparagine; Disease Models, Animal; Heart; Heart Rate; Injections, In

1972
Microscopic evaluation of experimentally induced cardiac necrosis in thiamine-deficient and control rats.
    American journal of veterinary research, 1972, Volume: 33, Issue:8

    Topics: Animals; Heart Diseases; Injections, Subcutaneous; Isoproterenol; Male; Necrosis; Rats; Rats, Inbred

1972
[Prevention of isoproterenol-induced myocardial necroses by lowering of the plasma calcium level with calcitonin].
    Pflugers Archiv : European journal of physiology, 1972, Volume: 332

    Topics: Animals; Calcitonin; Calcium; Drug Interactions; Heart; Heart Diseases; Isoproterenol; Necrosis; Rat

1972
[Effect of Cardilan-Spofa on the experimental isoprenaline necrosis of the myocardium in the rabbit].
    Ceskoslovenska farmacie, 1972, Volume: 21, Issue:6

    Topics: Animals; Asparagine; Heart Diseases; Isoproterenol; Lipid Metabolism; Magnesium; Myocardium; Necrosi

1972
[Myocardial lesions induced by isoprenaline and their prevention by cinnarizine].
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 199, Issue:1

    Topics: Animals; Cinnamates; Female; Inflammation; Injections, Subcutaneous; Isoproterenol; Myocardium; Necr

1972
Calcium as mediator of isoproterenol-induced myocardial necrosis.
    The American journal of pathology, 1972, Volume: 69, Issue:3

    Topics: Animals; Calcium; Heart; Injections, Intraperitoneal; Isoproterenol; Myocardial Infarction; Myocardi

1972
Reduced myocardial fibrosis after dimethylsulfoxide (DMSO) treatment of isoproterenol-induced myocardial necrosis in rats.
    The American journal of the medical sciences, 1971, Volume: 261, Issue:1

    Topics: Animals; Dimethyl Sulfoxide; Heart Diseases; Hexosamines; Hydroxyproline; Ischemia; Isoproterenol; M

1971
An experimental model of micronecrosis in the myocardium in rats.
    Acta medica Polona, 1971, Volume: 12, Issue:3

    Topics: Animals; Disease Models, Animal; Heart Diseases; Injections, Intraperitoneal; Isoproterenol; Myocard

1971
Effect of isoproterenol on rat plasma creatine phosphokinase activity.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 194, Issue:1

    Topics: Animals; Creatine Kinase; Isoenzymes; Isoproterenol; Male; Muscles; Myocardial Infarction; Myocardiu

1971
Time course of resistance to experimental cardiac necrosis in thiamine-deficient rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1971, Volume: 138, Issue:3

    Topics: Animals; Body Weight; Heart; Heart Diseases; Isoproterenol; Male; Necrosis; Rats; Thiamine Deficienc

1971
[Intracellular overloading with calcium as a decisive causative factor in the pathogenesis of noncoronary myocardial necroses].
    Verhandlungen der Deutschen Gesellschaft fur Kreislaufforschung, 1971, Volume: 37

    Topics: Animals; Calcium; Isoproterenol; Myocardial Infarction; Myocardium; Necrosis; Rats

1971
Myocardial resistance to isoprenaline in rats: variations with time.
    The Journal of pathology, 1971, Volume: 105, Issue:4

    Topics: Animals; Body Weight; Coronary Vessels; Drug Resistance; Heart; Injections, Subcutaneous; Isoprotere

1971
Acute myocardial anoxia. Anatomical changes and their possible relation to immunological processes.
    Cardiology, 1971, Volume: 56, Issue:1

    Topics: Animals; Antibodies; Autoimmune Diseases; Humans; Hypoxia; Isoproterenol; Lymphocytes; Microscopy, E

1971
Experimental studies on the healing of cardiac necrosis.
    Annals of the New York Academy of Sciences, 1969, Jan-31, Volume: 156, Issue:1

    Topics: Animals; Connective Tissue; Female; Isoproterenol; Ligation; Male; Myocardial Infarction; Myocardium

1969
Isoproterenol-induced cardiac necrosis.
    Annals of the New York Academy of Sciences, 1969, Jan-31, Volume: 156, Issue:1

    Topics: Animals; Desoxycorticosterone; Diet; Dogs; Drug Synergism; Female; Heart Diseases; Humans; Isoproter

1969
Histochemical and electron microscopical studies on the cardiac necroses produced by sympathomimetic agents.
    Annals of the New York Academy of Sciences, 1969, Jan-31, Volume: 156, Issue:1

    Topics: Animals; Carbohydrates; Epinephrine; Glycogen; Heart Diseases; Histocytochemistry; Isoproterenol; Ly

1969
Tissue electrolyte alteration in disseminated myocardial necrosis.
    Annals of the New York Academy of Sciences, 1969, Jan-31, Volume: 156, Issue:1

    Topics: Animals; Calcium; Electrolytes; Heart Diseases; Isoproterenol; Kidney; Magnesium; Myocardium; Necros

1969
Experimental "metabolic" cardiopathies and their relationship to human heart diseases. Concluding remarks.
    Annals of the New York Academy of Sciences, 1969, Jan-31, Volume: 156, Issue:1

    Topics: Animals; Cardiomyopathies; Heart Diseases; Heart Failure; Humans; Ischemia; Isoproterenol; Myocardia

1969
[Protective effect of organic Ca antagonists (iproveratril, D 600, prenylamine) against isoproterenol-induced myocardial necrosis].
    Pflugers Archiv : European journal of physiology, 1969, Volume: 312, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Calcium; Heart; Heart Diseases; Isoproterenol; Necrosis; Nitriles;

1969
Myocardial resistance. A study of its development against toxic doses of isoproterenol.
    Archives of pathology, 1970, Volume: 89, Issue:1

    Topics: Animals; Female; Heart; Isoproterenol; Kidney; Male; Myocardium; Necrosis; Rats

1970
The effects of dimethylsulfoxide (DMSO) on the healing of experimental myocardial necrosis.
    American heart journal, 1970, Volume: 79, Issue:3

    Topics: Animals; Dimethyl Sulfoxide; Disease Models, Animal; Isoproterenol; Male; Myocardial Infarction; Myo

1970
Physical activity, body fat and experimental cardiac necrosis.
    The British journal of nutrition, 1970, Volume: 24, Issue:1

    Topics: Adipose Tissue; Adrenal Glands; Animals; Body Temperature; Body Weight; Heart; Heart Diseases; Isopr

1970
LDH isoenzyme spectrum in the myocardium of rats after repeated doses of isoproterenol.
    Experientia, 1970, May-15, Volume: 26, Issue:5

    Topics: Anemia; Animals; Heart; Heart Diseases; Hypoxia; Isoenzymes; Isoproterenol; L-Lactate Dehydrogenase;

1970
Uptake and metabolism of noradrenaline--14C in rats after provoking damage to the heart muscle with isoprenaline.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 188, Issue:1

    Topics: Animals; Body Weight; Carbon Isotopes; Heart; Heart Diseases; In Vitro Techniques; Isoproterenol; Ki

1970
Tissue buffering capacity: its role in the prevention of isoproterenol induced necrosis.
    Life sciences. Pt. 1: Physiology and pharmacology, 1971, May-15, Volume: 10, Issue:10

    Topics: Animals; Buffers; Heart Diseases; Hydrochloric Acid; Hydrogen-Ion Concentration; Isoproterenol; Male

1971
[Fluorescence microscopic and enzyme histochemical findings in toxically induced heart muscle necrosis].
    Gegenbaurs morphologisches Jahrbuch, 1967, Volume: 111, Issue:1

    Topics: Animals; Coronary Disease; Cytoplasmic Granules; Diagnosis, Differential; Heart; Histocytochemistry;

1967
Isoproterenol-induced acute experimental cardiac necrosis in the turtle (Testudo Horsfieldi).
    American heart journal, 1968, Volume: 76, Issue:5

    Topics: Animals; Coronary Disease; Coronary Vessels; Heart; Isoproterenol; Myocardium; Necrosis; Turtles

1968
Differential effects of hydroxyurea on survival of proliferating cells in vivo.
    Cancer research, 1969, Volume: 29, Issue:1

    Topics: Animals; Cell Biology; Depression, Chemical; DNA; Epithelial Cells; Folic Acid; Hydroxyurea; Intesti

1969
Temperature and experimental acute cardiac necrosis.
    Canadian journal of physiology and pharmacology, 1969, Volume: 47, Issue:3

    Topics: Animals; Body Temperature Regulation; Cardiomyopathies; Crowding; Environment; Isoproterenol; Male;

1969
Possible protective action of antialdosterone compounds in myocardial necrosis in rats.
    British journal of pharmacology, 1969, Volume: 35, Issue:3

    Topics: Animals; Cardiomyopathies; Isoproterenol; Mineralocorticoid Receptor Antagonists; Necrosis; Rats; Sp

1969
Acute cardiac infarct like necrosis in high altitude adapted rats.
    Physiologia bohemoslovenica, 1965, Volume: 14, Issue:6

    Topics: Acclimatization; Altitude; Animals; Heart; Isoproterenol; Male; Myocardial Infarction; Myocardium; N

1965
Effect of nicotine on cardiac necrosis induced by isoproterenol.
    American heart journal, 1966, Volume: 71, Issue:3

    Topics: Animals; Female; Heart; Isoproterenol; Necrosis; Nicotine; Rats

1966
The protective effect of hyperbaric oxygenation upon isoproterenol-induced myocardial necrosis in Syrian hamsters.
    Medicina thoracalis, 1966, Volume: 23, Issue:3

    Topics: Animals; Cricetinae; Female; Heart Diseases; Hyperbaric Oxygenation; Isoproterenol; Male; Necrosis

1966
Protection of rats from isoproterenol induced myocardial necrosis by trolnitrate phosphate (Metamine).
    Experientia, 1966, Feb-15, Volume: 22, Issue:2

    Topics: Animals; Cardiomyopathies; Drug Antagonism; Isoproterenol; Necrosis; Nitrates; Rats; Vasodilator Age

1966
Isoproterenol induced myocardial lesions in the immunized and non-immunized rat. II. Histopathological lesions after specific immunization.
    Immunology, 1966, Volume: 10, Issue:2

    Topics: Animals; Autoantibodies; Heart; Hemagglutination Tests; Isoproterenol; Myocardium; Necrosis; Rabbits

1966
Dose-time effect of isoproterenol on aspartate amino-transferase and necrosis of the rat heart.
    Toxicology and applied pharmacology, 1966, Volume: 8, Issue:3

    Topics: Animals; Aspartate Aminotransferases; Cardiomyopathies; Isoproterenol; Male; Myocardium; Necrosis; R

1966
The effect of a beta adrenergic blocking agent on chemical changes in isoproterenol-induced myocardial necrosis.
    Canadian journal of physiology and pharmacology, 1966, Volume: 44, Issue:4

    Topics: Adenine Nucleotides; Animals; Body Weight; Cholesterol; Creatine; Glycogen; Heart; Isoproterenol; La

1966