isoproterenol has been researched along with Muscle Relaxation in 622 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In previous reports, we have documented decreased in vitro airway smooth muscle responses to isoproterenol (ISO) in fresh postmortem trachea and bronchus from subjects with fatal asthma." | 7.68 | A comparison of beta-adrenergic receptors and in vitro relaxant responses to isoproterenol in asthmatic airway smooth muscle. ( Bai, TR; Barnes, PJ; Mak, JC, 1992) |
| "The facilitating effect of nifedipine on isoproterenol induced airway smooth muscle relaxation was studied in guinea pig tracheas." | 7.67 | Facilitation of isoproterenol induced airway smooth muscle relaxation by nifedipine. ( Elguindi, AS; Smith, JK; Speir, WA, 1985) |
| "Substance P was added to methacholine precontracted bronchial rings with and without epithelium." | 5.37 | Carbon dioxide enhances substance P-induced epithelium-dependent bronchial smooth muscle relaxation in Sprague-Dawley rats. ( Choudhury, P; El Mays, TY; Green, FH; Hollenberg, MD; Saifeddine, M, 2011) |
| "To examine the role of contractile agonist-induced activation of protein kinase C (PKC) in functional antagonism of airway smooth muscle contraction by beta-adrenoceptor agonists, we examined the effects of the specific PKC-inhibitor GF 109203X (2-[1-(3-dimethylaminopropyl)-1H-indol-3-yl]-3-(1H-indol-3-yl) maleimide) on isoprenaline-induced relaxation of bovine tracheal smooth muscle contracted by various concentrations of methacholine and histamine." | 3.73 | Potentiation of beta-adrenoceptor function in bovine tracheal smooth muscle by inhibition of protein kinase C. ( Boterman, M; Elzinga, CR; Eppens, PB; Meurs, H; Wagemakers, D; Zaagsma, J, 2005) |
| " The aim of this study was to elucidate the effects of milrinone, a PDE III inhibitor, on d-tubocurarine (dTc)-induced muscle relaxation in vitro and then to compare its effects with those of other activators of the adenylate cyclase (AC) system (aminophylline, a non-selective PDE inhibitor; forskolin, a direct AC activator; and isoproterenol, a beta-adrenoceptor agonist)." | 3.70 | Milrinone, a phosphodiesterase III inhibitor, antagonizes the neuromuscular blocking effect of a non-depolarizing muscle relaxant in vitro. ( Aimono, M; Fujimura, N; Iwasaki, H; Nakayama, Y; Namiki, A; Narimatsu, E, 1999) |
| "), as well as (+/-)-propranolol, produced a dose-dependent bradycardia response and a temporary pressor action in urethane-anaesthetized normotensive Wistar rats." | 3.69 | Capsinolol: the first beta-adrenoceptor blocker with an associated calcitonin gene-related peptide releasing activity in the heart. ( Chen, IJ; Lin, YT; Lo, YC; Sheu, SH; Yeh, JL, 1996) |
| "Intraperitoneal injection of endotoxin resulted in bronchial hyperreactivity to histamine in guinea pigs." | 3.69 | Effect of Apafant on bronchial hyperresponsiveness and down-regulation of beta-adrenoceptors induced by endotoxin in guinea pigs. ( Hayakawa, T; Kamei, C; Kishida, H; Mihara, T; Nakayama, Y; Sugimoto, Y, 1997) |
| " The involvement of cyclic AMP-dependent protein kinase (PKA) and cyclic GMP-dependent protein kinase (PKC) in the effects of cyclic AMP-elevating agents on vascular smooth muscle relaxation, cyclic nucleotide dependent-protein kinase activities and ATP-induced calcium signalling ([Ca2+]i was studied in rat aorta." | 3.69 | Involvement of cyclic nucleotide-dependent protein kinases in cyclic AMP-mediated vasorelaxation. ( Eckly-Michel, A; Lugnier, C; Martin, V, 1997) |
| "The purpose of this study was to examine and compare pulmonary vascular smooth muscle relaxation by clinically used agents as related to cGMP mediation (sodium nitroprusside, nitroglycerin) and cAMP mediation (isoproterenol, prostaglandin E1 (PGE1), and amrinone) in isolated rat pulmonary arterial rings." | 3.69 | Pulmonary vascular smooth muscle relaxation by cGMP- versus cAMP-mediated mechanisms. ( Banerjee, A; Fullerton, DA; Hahn, AR; Harken, AH, 1994) |
| "The influence of deuterium oxide (D2O) on calcium-dependent vascular smooth muscle contraction was investigated." | 3.68 | Deuterium oxide reduces agonist and depolarization-induced contraction of rat aortic rings. ( Liepins, A; McWilliam, TM; Rankin, AJ, 1990) |
| " In addition, smooth muscle contraction in response to potassium ions (voltage-dependent) or prostaglandin F2 alpha (receptor-dependent) and relaxation in response to isoproterenol (cyclic adenosine monophosphate-mediated) or sodium nitroprusside (cyclic guanosine monophosphate-mediated) was unaltered after exposure to cardioplegic solution or hypothermia." | 3.68 | Crystalloid cardioplegia and hypothermia do not impair endothelium-dependent relaxation or damage vascular smooth muscle of epicardial coronary arteries. ( Evora, PR; Pearson, PJ; Schaff, HV, 1992) |
| " We wondered if prolonged infusion of isoproterenol or PGE1 would cause desensitization of smooth muscle relaxation and used the dorsal hand-vein compliance technique to investigate this question." | 3.68 | Desensitization of beta-adrenoceptor- and prostaglandin E1 receptor-mediated human vascular smooth muscle relaxation. ( Blaschke, TF; Hoffman, BB; Vincent, J, 1992) |
| "The molecular pharmacology of a new putative long-acting bronchodilator TA 2005 (8-hydroxy-5-[(1R)-1-hydroxy-2-[N-[(1R)-2-(p-methoxy-phenyl)- 1-methylethyl]amino]ethyl]carbostyril hydrochloride) has been compared with that of the reference compounds isoprenaline and salbutamol in both methacholine (3 x 10(-6) M) precontracted guinea pig tracheal smooth muscle relaxation and in bovine trapezium muscle binding experiments." | 3.68 | Atypical molecular pharmacology of a new long-acting beta 2-adrenoceptor agonist, TA 2005. ( Bast, A; Donnell, D; Voss, HP, 1992) |
| "In previous reports, we have documented decreased in vitro airway smooth muscle responses to isoproterenol (ISO) in fresh postmortem trachea and bronchus from subjects with fatal asthma." | 3.68 | A comparison of beta-adrenergic receptors and in vitro relaxant responses to isoproterenol in asthmatic airway smooth muscle. ( Bai, TR; Barnes, PJ; Mak, JC, 1992) |
| "The facilitating effect of nifedipine on isoproterenol induced airway smooth muscle relaxation was studied in guinea pig tracheas." | 3.67 | Facilitation of isoproterenol induced airway smooth muscle relaxation by nifedipine. ( Elguindi, AS; Smith, JK; Speir, WA, 1985) |
| " The autoradiographic distribution of alpha 1-adrenoceptors was investigated in non-diseased and asthmatic human lung by use of [3H]-prazosin (H-PZ)." | 3.67 | Alpha 1-adrenoceptor function and autoradiographic distribution in human asthmatic lung. ( Goldie, RG; Paterson, JW; Rigby, PJ; Spina, D, 1989) |
| " Eicosatetraynoic acid (50 microM), nordihydroguairetic acid (50 microM) and QUIN (10 microM) do not exert significant inhibitory effects at the level of smooth muscle relaxation mechanisms as isoproterenol-induced relaxation was resistant to inhibition by these agents." | 3.66 | Endothelium-dependent relaxation of rabbit aorta. II. Inhibition of relaxation stimulated by methacholine and A23187 with antagonists of arachidonic acid metabolism. ( Peach, MJ; Singer, HA, 1983) |
| "Asthma affects millions of people worldwide and its prevalence is increasing." | 1.62 | Ginger metabolites and metabolite-inspired synthetic products modulate intracellular calcium and relax airway smooth muscle. ( Emala, CW; Luković, E; Perez-Zoghbi, JF; Sang, S; Zhang, Y; Zhu, Y, 2021) |
| "Quercetin is a naturally derived PDE4-selective inhibitor found in fruits, vegetables, and tea." | 1.39 | Quercetin acutely relaxes airway smooth muscle and potentiates β-agonist-induced relaxation via dual phosphodiesterase inhibition of PLCβ and PDE4. ( Emala, CW; Townsend, EA, 2013) |
| "Glycine treatment during tachykinin- and acetylcholine-induced contractions significantly decreased the maintenance of muscle force compared to control." | 1.37 | Novel expression of a functional glycine receptor chloride channel that attenuates contraction in airway smooth muscle. ( Emala, CW; Gallos, G; Xu, D; Yim, PD; Zhang, Y, 2011) |
| "Substance P was added to methacholine precontracted bronchial rings with and without epithelium." | 1.37 | Carbon dioxide enhances substance P-induced epithelium-dependent bronchial smooth muscle relaxation in Sprague-Dawley rats. ( Choudhury, P; El Mays, TY; Green, FH; Hollenberg, MD; Saifeddine, M, 2011) |
| "(-)-Isoproterenol was less potent and efficient in relaxing detrusor from cav-1 KO (-logEC(50)M, 7." | 1.35 | Catecholamines relax detrusor through beta 2-adrenoceptors in mouse and beta 3-adrenoceptors in man. ( Eichhorn, B; Grimm, MO; Kaumann, AJ; Ravens, U; Wirth, MP; Wuest, M, 2009) |
| "L-carnitine treatment restored the hyporesponsiveness of isoprenaline and the hyperresponsiveness of adenosine-elicited relaxation." | 1.35 | L-carnitine treatment partially restores urinary bladder function of streptozotocin diabetic rats. ( Gur, S; Irat, AM, 2008) |
| "An association between chronic renal failure (CRF) and gastroesophageal reflux (GER) is well known." | 1.34 | Effect of chronic renal failure on foregut smooth muscle reactivity: an experimental study. ( Tugay, M; Utkan, T; Yazir, Y; Yildiz, F, 2007) |
| " The dose-response curve to isoproterenol in naive sphincters or sphincters pre-treated with atropine indicated that muscarinic blockade decreased the EC(50) rather than potentiated maximal beta-adrenergic relaxation." | 1.32 | Muscarinic blockers potentiate beta-adrenergic relaxation of bovine iris sphincter. ( Barilan, A; Geyer, O; Nachman-Rubinstein, R; Oron, Y, 2003) |
| "Methimazole (0." | 1.31 | Effect of hypothyroidism on beta-adrenoceptor-mediated relaxation in the rat thoracic aortae. A time-dependent study. ( Ampong, B; Honda, H; Kogo, H, 2002) |
| "Ulcerative colitis is characterized by dysfunctional motility." | 1.31 | Studies on the expression and function of beta-3-adrenoceptors in the colon of rats with acetic acid-induced colitis. ( Hussein, SM; Khan, I; Oriowo, M, 2002) |
| "Diltiazem was the most potent airway relaxant, and amrinone was less potent in these experiments." | 1.31 | Comparative effect of amrinone, aminophylline and diltiazem on rat airway smooth muscle. ( Kiyota, T; Matsuda, F; Sadohara, T; Sugahara, K; Sugita, M; Terasaki, H, 2000) |
| " Bronchial rings were incubated with normal or immune serum (100 microl ml(-1) for 2 h) and dose-response curves to TDI (0." | 1.31 | Serum-mediated relaxant response to toluene diisocyanate (TDI) in isolated guinea-pig bronchi. ( Boschetto, P; Chitano, P; De Marzo, N; Fabbri, LM; Faggian, D; Jovine, L; Mapp, CE; Plebani, M, 2001) |
| "Levosimendan has been reported to increase cardiac Ca(2+) sensitivity, thereby not enhancing intracellular Ca(2+) or diastolic tension." | 1.31 | Beneficial effects of the Ca(2+) sensitizer levosimendan in human myocardium. ( Brixius, K; Reicke, S; Schwinger, RH, 2002) |
| "In S-ketoprofen-pretreated rats, the relaxant effect of MEN 11420 was significant at 2 but not at 1 ml of distension, and that of isoprenaline was reduced by 50% at both 1 and 2 ml." | 1.30 | Bladder distension and activation of the efferent function of sensory fibres: similarities with the effect of capsaicin. ( Criscuoli, M; Dion, S; Giuliani, S; Lecci, A; Maggi, CA; Santicioli, P; Tramontana, M, 1998) |
| "Siguazodan was 100 fold more active than rolipram in pig tissues indicating the type III isoenzyme may be of greater functional significance in this tissue." | 1.29 | Comparison of the effects of selective inhibitors of phosphodiesterase types III and IV in airway smooth muscle with differing beta-adrenoceptor subtypes. ( Karlsson, JA; Raeburn, D; Tomkinson, A, 1993) |
| "Pretreatment with verapamil (1 or 10 microM), nifedipine (0." | 1.29 | The effects of phorbol 12,13-diacetate on responses of guinea-pig isolated trachea to methylxanthines, isoprenaline and ryanodine. ( Cortijo, J; Morcillo, EJ; Sanz, CM; Small, RC; Villagrasa, V, 1994) |
| "1 ml), and dose-response curves to levcromakalim (a KATP channel opener) or isoproterenol were constructed." | 1.29 | Role of potassium channels in hypoxic relaxation of porcine bronchi in vitro. ( Croxton, TL; Fernandes, LB; Hirshman, CA; Lindeman, KS, 1994) |
| "Hyperthyroidism was induced by feeding rats for 28 days with 5 mg/kg L-thyroxine (T4)-containing rat chow." | 1.29 | The influence of hyperthyroidism on beta-adrenoceptor-mediated relaxation of isolated small mesenteric arteries. ( Pfaffendorf, M; van Zwieten, PA; Winkler Prins, EA; Zwaveling, J, 1996) |
| "In methylene blue-treated rings isoproterenol- and forskolin-induced relaxation were prevented in both endothelium-intact and -denuded rings, but the inhibitory effect of methylene blue were significantly more in rings with endothelium than in those without." | 1.29 | beta-Adrenoceptor activates endothelium-dependent release of nitric oxide in rat aorta. ( Daniel, EE; Kwan, CY; Zheng, XF, 1995) |
| "Pretreatment with BRL 37344 induced a marked desensitization of the distal colon and fundic strips but not the aorta and carotid artery to isoprenaline." | 1.29 | Different atypical beta-adrenoceptors mediate isoprenaline-induced relaxation in vascular and non-vascular smooth muscles. ( Oriowo, MA, 1995) |
| "Pretreatment with nicorandil 3 x 10(-7) and 3 x 10(-6) M potentiated the relaxation induced by ISO." | 1.29 | Potentiating effect of nicorandil, an antianginal agent, on relaxation induced by isoproterenol in isolated rat aorta: involvement of cyclic GMP-inhibitable cyclic AMP phosphodiesterase. ( Inoue, M; Morikawa, M; Satake, N; Shibata, S; Zhou, Q, 1995) |
| "Cromakalim (BRL 34915) is a potassium channel opener with therapeutic potential as a bronchodilator in asthma." | 1.28 | The relaxant effects of cromakalim (BRL 34915) on human isolated airway smooth muscle. ( Cortijo, J; Morcillo, E; Paris, F; Pedrós, C; Perpiñá, M; Sarriá, B, 1992) |
| "It is not clear whether regression of cardiac hypertrophy normalizes cardiac contractility." | 1.28 | Effect of enalapril on the inotropic response to isoproterenol in renal hypertensive rats. ( Fontán, M; Gómez Llambí, H; Mazzadi, A; Taquini, CM, 1992) |
| "Milrinone was more potent as a vasorelaxant in coronary arteries relative to cerebral or renal arteries regardless of the mode of contraction; amrinone was coronary selective with K+ contraction only." | 1.28 | Differential vasorelaxant effects of milrinone and amrinone on contractile responses of canine coronary, cerebral, and renal arteries. ( Alousi, AA; Evans, DB; Grant, AM; Harris, AL; Silver, PJ, 1989) |
| "2." | 1.28 | Dicentrine, a natural vascular alpha 1-adrenoceptor antagonist, isolated from Lindera megaphylla. ( Chen, CC; Huang, TF; Huang, YL; Ko, FN; Teng, CM; Yu, SM, 1991) |
| " In tissues precontracted with methacholine, 11-([[2-(diethylamino)methyl]-1-piperidinyl]acetyl)5,11- dihydro-6H-pyrido[2,3-6][1,4]benzodiazepine-6-one (AF-DX 116), a selective M2 antagonist, shifted dose-response curves to both isoproterenol and forskolin significantly to the left." | 1.28 | M2 muscarinic receptors inhibit isoproterenol-induced relaxation of canine airway smooth muscle. ( Fernandes, LB; Fryer, AD; Hirshman, CA, 1992) |
| " N-Nitro-L-arginine (NOLA) (5 x 10(-5) to 10(-4) M), an inhibitor of NO synthase, and haemoglobin (10(-5) M), which reduces bioavailability of NO, both reduced the amplitude of nerve-mediated relaxations to less than 50%, without affecting the ability of the muscle to relax." | 1.28 | Evidence that nitric oxide participates in non-adrenergic inhibitory transmission to intestinal muscle in the guinea-pig. ( Furness, JB; Murphy, R; Shuttleworth, CW, 1991) |
| " Acute and chronic administration of Chlo (45 mg kg-1, i." | 1.28 | Mode of inhibitory actions of acute and chronic chloroquine administration on the electrically stimulated mouse diaphragm in vitro. ( Okwuasaba, FK; Otubu, JA; Udoh, FV, 1990) |
| " It is concluded that chronic administration of isoproterenol to guinea pigs caused marked changes in beta adrenoceptor function in the lung tissue." | 1.28 | Chronic isoproterenol administration causes altered beta adrenoceptor-Gs-coupling in guinea pig lung. ( Abrahamsson, T; Nerme, V; Vauquelin, G, 1990) |
| "Charybdotoxin (ChTX) is a potent blocker of the high-conductance Ca(++)-activated K+ channel in smooth muscle and produces a concentration-dependent contraction of guinea pig trachea." | 1.28 | Selective inhibition of relaxation of guinea-pig trachea by charybdotoxin, a potent Ca(++)-activated K+ channel inhibitor. ( Charette, L; Garcia, ML; Jones, TR; Kaczorowski, GJ, 1990) |
| "Bradykinin (BK) did not increase cyclic AMP production in cultured rat duodenum smooth muscle cells." | 1.28 | Mechanism of the relaxant response of the rat duodenum to bradykinin. ( Feres, T; Funari, CC; Paiva, AC; Paiva, TB, 1992) |
| " Compound MV 8612 (8 and 16 microM) and MV 8610 (12 and 24 microM) caused a graded rightward displacement of BK dose-response curves in the isolated guinea pig trachea (dose ratio 2- to 4-fold)." | 1.28 | Effect of compounds from Mandevilla velutina on bradykinin-mediated contractile and relaxant responses of the isolated guinea pig trachea. ( Calixto, JB; Cruz, AB; Medeiros, YS; Yunes, RA, 1992) |
| " The two events generally paralleled one another when analyzed in terms of dose-response and time-response relationships." | 1.27 | Role of cyclic AMP in adrenergically-induced tracheal muscle relaxation. ( Lau, YS; Lum, BK, 1983) |
| " Photoinactivation of beta-adrenoceptors caused a considerable parallel shift in the dose-response curve of isoprenaline." | 1.27 | Relationship between intrinsic activity of beta-adrenoceptor agonist and amount of spare receptors in guinea pig taenia caecum. ( Koike, K; Takayanagi, I, 1983) |
| "Verapamil was found to produce considerable tracheal smooth muscle relaxation from a threshold concentration of 2 X 10(-7) M and with maximum effect at 10(-3) M." | 1.27 | The potential bronchodilator action of verapamil. ( Cade, JF; Clegg, EA; Moulds, RF; Pain, MC; Rubinfeld, AR; Santamaria, JD, 1984) |
| "Pretreatment with indomethacin (8." | 1.27 | Bronchodilator-mediated relaxation of normal and ovalbumin-sensitized guinea-pig airways: lack of correlation with lung adenylate cyclase activation. ( Burka, JF; Saad, MH, 1984) |
| "When verapamil was used to relax EFS and matched methacholine contractions, cervical trachealis was completely relaxed whereas thoracic trachealis relaxed to 15% of induced tone." | 1.27 | Regional differences in relaxation of electric field-stimulated canine airway smooth muscle by verapamil, isoproterenol and prostaglandin E2. ( Abel, PW; Moore, DH; Puckett, AM; Rinard, GA; Walter, JB, 1986) |
| " Apamin inhibited the transmural nerve stimulation-induced relaxation and shifted the dose-response curve for VIP to the right." | 1.27 | Similarities between the relaxations induced by vasoactive intestinal peptide and by stimulation of the non-adrenergic non-cholinergic neurons in the rat stomach. ( Kamata, K; Kasuya, Y; Sakamoto, A, 1988) |
| "Propranolol was a competitive antagonist of selected TMQ analogues in guinea pig trachea and atria, thus confirming the beta-adrenoceptor actions of these drugs." | 1.27 | Pharmacological evaluation of the beta-adrenoceptor agonist and thromboxane antagonist properties of N-substituted trimetoquinol analogues. ( Adejare, A; Fedyna, JS; Feller, DR; Miller, DD, 1987) |
| "(+)-Clenbuterol was at least 1,000 times less potent in this respect." | 1.27 | Steric aspects of agonism and antagonism at beta-adrenoceptors: experiments with the enantiomers of clenbuterol. ( Waldeck, B; Widmark, E, 1985) |
| "Isoproterenol was able to relax these forskolin-treated, PGE1-contracted muscles with no further increase in cyclic AMP levels." | 1.27 | Effects of prostaglandin E1, isoproterenol and forskolin on cyclic AMP levels and tension in rabbit aortic rings. ( Diamond, J; Vegesna, RV, 1986) |
| "Isoproterenol treatment of K+-contracted tissues led to relaxation that was slow and incomplete, and it had very little effect on calmodulin-stimulated phosphodiesterase activity." | 1.27 | Effects of isoproterenol on active force and Ca2+ X calmodulin-sensitive phosphodiesterase activity in porcine coronary artery. ( Miller, JR; Wells, JN, 1987) |
| " This effect was evident by a decrease of the maximal response of the dose-response curves to isoprenaline, whereas the EC50 values did not change." | 1.27 | Dual effects of Haemophilus influenzae on guinea pig tracheal beta-adrenergic receptor function: involvement of oxygen-centered radicals from pulmonary macrophages. ( Engels, F; Nijkamp, FP; Oosting, RS, 1987) |
| "We tested the hypothesis that maximal bronchoconstriction in humans in vivo is limited by the maximal contractility of airway smooth muscle by comparison of complete in vivo and in vitro dose-response curves to methacholine in 10 nonasthmatic subjects who were scheduled for thoracotomy because of malignancies." | 1.27 | Comparison of maximal bronchoconstriction in vivo and airway smooth muscle responses in vitro in nonasthmatic humans. ( de Jongste, JC; Kerrebijn, KF; Mons, H; Sterk, PJ; Timmers, MC; Willems, LN, 1988) |
| "Prazosin was 300 times more active than rauwolscine in inhibiting NA-induced contractions." | 1.27 | Comparison of the responses to drugs acting on adrenoreceptors and muscarinic receptors in human isolated corpus cavernosum and cavernous artery. ( Andersson, KE; Hedlund, H, 1985) |
| " For each agent tested in this study, dose-response curves were established." | 1.27 | Micturition in the unanesthetized rat: spinal vs. peripheral pharmacology of the adrenergic system. ( Durant, PA; Lucas, PC; Yaksh, TL, 1988) |
| " The dose-response curves for drugs were constructed 8 weeks after treatment with STZ." | 1.27 | Changes in sensitivity of the rat stomach fundus to various drugs in streptozotocin-induced diabetic rats. ( Kamata, K; Kasuya, Y; Sakamoto, A, 1988) |
| "Isoproterenol was applied to one set of tracheal and parenchymal strips, and one of the purine derivatives to the other to produce cumulative concentration-effect relationships." | 1.27 | Inhibitory effects of selected purine derivatives on guinea pig pulmonary tissues. ( Deason, RD; Flory, W; O'Malley, NA; Venugopalan, CS, 1986) |
| " Propranolol also shifted the dose-response curves to the right, but was apparently more potent in preparations with basal tone than in tissues where high tone was induced by carbachol or K+." | 1.27 | Noradrenergic and non-noradrenergic relaxation at basal and high tone levels in the guinea-pig tracheal smooth muscle. ( Abe, M; Furukawa, T, 1986) |
| "(+)-Pindolol was less potent as antagonist of the relaxant effects of (-)-noradrenaline on trachea than against those of (-)-adrenaline, (-)-isoprenaline and (+/-)-salbutamol." | 1.27 | Stimulant and blocking effects of optical isomers of pindolol on the sinoatrial node and trachea of guinea pig. Role of beta-adrenoceptor subtypes in the dissociation between blockade and stimulation. ( Kaumann, AJ; Lemoine, H; Walter, M, 1984) |
| " No long-lasting effect of the alpha-adrenergic blocker was apparent since the response to norepinephrine was not altered following a 1-hour washout of phentolamine after the isoproterenol dose-response curve." | 1.27 | Phentolamine and rat aortic smooth muscle responsiveness to potassium chloride, isoproterenol and norepinephrine. ( Katovich, MJ; Soltis, EE, 1985) |
| " Construction of dose-response curves, however, revealed antagonism of all three parameters by propranolol and different sensitivities of the parameters to isoprenaline." | 1.26 | The beta-adrenoceptors responsible for a direct relaxation of the uncontracted nictitating membrane of the anaesthetized cat. ( Broadley, KJ, 1977) |
| "Proxyphylline was excreted in urine both an unchanged compound (12." | 1.26 | Human metabolism of 7-substituted theophyllines: N3-demethylation and lack of oxidation of proxyphylline. ( Garcia, I; Segura, J; Tarrus, E, 1981) |
| "Clenbuterol was a potent partial beta adrenoceptor agonist in both tissues based on the following observations: 1." | 1.26 | Analysis of the beta 1 and beta 2 adrenoceptor interactions of the partial agonist, clenbuterol (NAB365), in the rat jugular vein and atria. ( Bemis, KG; Cohen, ML; Wiley, KS, 1982) |
| "5 Indomethacin treatment reversed the isoprenaline desensitization induced by chronic treatment (0." | 1.26 | Tolerance of guinea-pig airway muscle preparations to relaxant agonists induced by chronic exposure to isoprenaline in vivo. ( Brink, C, 1981) |
| " Dose-response curves to the relaxant effects of isoprenaline, salbutamol, adrenaline and noradrenaline were determined on the partially contracted smooth muscles of the cat nictitating membrane following alpha-adrenoreceptor blockade in order to test the hypothesis of a causal relationship between the inhibition of neuronal uptake and denervation supersensitivity." | 1.26 | Denervation and beta-adrenoreceptors of the cat nictitating membrane. ( Nickerson, M; Varma, DR, 1981) |
| " The dose-response curve to dopamine was shifted to the right by droperidol in concentrations above 3 X 10(-5) M." | 1.26 | Antagonism by droperidol of dopamine-induced relaxation in isolated dog arteries. ( Hatano, Y; Toda, N, 1979) |
| "Trapidil could inhibit these effects of 5-HT or phenylephrine." | 1.26 | Analysis of relaxant effects of trapidil in isolated dog coronary artery. ( Fukai, R; Higuchi, M; Hirata, A; Kondoh, G; Sakanashi, M; Yoshikawa, Y, 1980) |
| " The dose-response curves for isoprenaline were shifted to the right on treatment with practolol." | 1.26 | Distribution and characterization of the adrenoceptors in dog coronary arteries. ( Morishita, H, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 215 (34.57) | 18.7374 |
| 1990's | 257 (41.32) | 18.2507 |
| 2000's | 109 (17.52) | 29.6817 |
| 2010's | 35 (5.63) | 24.3611 |
| 2020's | 6 (0.96) | 2.80 |
| Authors | Studies |
|---|---|
| Jen, T | 2 |
| Frazee, JS | 2 |
| Schwartz, MS | 2 |
| Kaiser, C | 2 |
| Erhard, KF | 1 |
| Adejare, A | 2 |
| Nie, JY | 1 |
| Hebel, D | 1 |
| Brackett, LE | 1 |
| Choi, O | 1 |
| Gusovsky, F | 1 |
| Padgett, WL | 1 |
| Daly, JW | 1 |
| Creveling, CR | 1 |
| Kirk, KL | 1 |
| Tanaka, N | 1 |
| Tamai, T | 1 |
| Mukaiyama, H | 1 |
| Hirabayashi, A | 1 |
| Muranaka, H | 1 |
| Akahane, S | 3 |
| Miyata, H | 3 |
| Akahane, M | 7 |
| Luković, E | 1 |
| Perez-Zoghbi, JF | 1 |
| Zhang, Y | 6 |
| Zhu, Y | 1 |
| Sang, S | 1 |
| Emala, CW | 5 |
| Gebski, EB | 1 |
| Parikh, V | 1 |
| Lam, H | 1 |
| Kim, N | 1 |
| Bochkov, YA | 1 |
| Cao, G | 1 |
| Panettieri, RA | 3 |
| Kurten, R | 1 |
| Gern, J | 1 |
| An, SS | 3 |
| Koziol-White, CJ | 2 |
| Obara, K | 4 |
| Shigematsu, M | 1 |
| Takahasi, H | 1 |
| Iiboshi, Y | 1 |
| Yoshioka, K | 2 |
| Kasuya, Y | 6 |
| Tanaka, Y | 9 |
| Yamaki, F | 5 |
| Koike, A | 1 |
| Kono, H | 1 |
| Zhang, X | 1 |
| Dellabianca, A | 1 |
| Beretta, C | 1 |
| Faniglione, M | 1 |
| De Angelis, S | 1 |
| Colucci, M | 1 |
| Cervio, M | 1 |
| Tonini, S | 1 |
| Candura, SM | 1 |
| Nayak, AP | 1 |
| Lim, JM | 1 |
| Arbel, E | 1 |
| Wang, R | 1 |
| Villalba, DR | 1 |
| Nguyen, TL | 1 |
| Schaible, N | 1 |
| Krishnan, R | 1 |
| Tang, DD | 1 |
| Penn, RB | 3 |
| Chino, D | 1 |
| Sone, T | 1 |
| Yamazaki, K | 1 |
| Tsuruoka, Y | 1 |
| Yamagishi, R | 1 |
| Shiina, S | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| To Explore the Effect of beta3-adrenoceptor Agonist on Patients With Overactive Bladder and Develop Its Urinary Biomarker[NCT04693897] | 400 participants (Anticipated) | Observational [Patient Registry] | 2021-03-01 | Not yet recruiting | |||
| A Randomized, Controlled,14-Treatment Day, Multicenter Study to Determine the Optimal Efficacious and Safe Dose of CHF 4226 in a Metered Dose Inhaler in Treating Patients With Chronic Obstructive Pulmonary Disease[NCT00605891] | Phase 2 | 278 participants (Actual) | Interventional | 2006-10-31 | Completed | ||
| Evaluation of the Effect of 2 Weeks Treatment With CHF 4226 pMDI 2µg and 4µg, Given Once Daily in the Morning, on 24-Hour FEV1 in Patients With COPD[NCT00640484] | Phase 2 | 57 participants (Actual) | Interventional | 2008-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for isoproterenol and Muscle Relaxation
| Article | Year |
|---|---|
Smooth muscle physiology and effect of bladder and urethra muscle length/tension on response to stimulation. Part I. Review.
Topics: Action Potentials; Animals; Cats; Dogs; Electric Stimulation; Guinea Pigs; Isoproterenol; Male; Memb | 1980 |
[Reactivity of cerebrovascular smooth muscle to drugs (author's transl)].
Topics: Acetylcholine; Animals; Cats; Cattle; Cerebral Arteries; Dogs; Dopamine; Histamine; Humans; In Vitro | 1979 |
1 trial available for isoproterenol and Muscle Relaxation
| Article | Year |
|---|---|
The effect of vasoactive intestinal polypeptide on the lower esophageal sphincter in achalasia.
Topics: Adolescent; Adult; Esophageal Achalasia; Esophagogastric Junction; Female; Humans; Isoproterenol; Ma | 1992 |
619 other studies available for isoproterenol and Muscle Relaxation
| Article | Year |
|---|---|
Adrenerigic agents. 7.1 Synthesis and beta-adrenergic agonist activity of several 2-pyridylethanolamines.
Topics: Adrenergic beta-Agonists; Animals; Ethanolamines; Guinea Pigs; Heart Rate; In Vitro Techniques; Musc | 1977 |
Adrenergic agents. 8.1 Synthesis and beta-adrenergic agonist activity of some 3-tert-butylamino-2-(substituted phenyl)-1-propanols.
Topics: Adrenergic beta-Agonists; Animals; Guinea Pigs; Heart Rate; In Vitro Techniques; Muscle Relaxation; | 1977 |
Effect of fluorine substitution on the adrenergic properties of 3-(tert-butylamino)-1-(3,4-dihydroxyphenoxy)-2-propanol.
Topics: Adrenergic beta-Agonists; Animals; Cell Membrane; Cerebral Cortex; Chemical Phenomena; Chemistry; Cy | 1991 |
Discovery of novel N-phenylglycine derivatives as potent and selective beta(3)-adrenoceptor agonists for the treatment of frequent urination and urinary incontinence.
Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Female; Ferrets; Glycine; Heart Rate; In Vitro Te | 2001 |
Ginger metabolites and metabolite-inspired synthetic products modulate intracellular calcium and relax airway smooth muscle.
Topics: Animals; Asthma; Bronchoconstriction; Calcium; Cyclic Nucleotide Phosphodiesterases, Type 4; Humans; | 2021 |
Rhinovirus C15 Attenuates Relaxation and cAMP Production in Human Airways and Smooth Muscle.
Topics: Adult; Child; Colforsin; Enterovirus Infections; Formoterol Fumarate; Humans; Isoproterenol; Lung; M | 2023 |
Pharmacological properties of β-adrenoceptors mediating rat superior mesenteric artery relaxation and the effects of chemical sympathetic denervation.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Isoproterenol; Male; Mesenteric Arte | 2020 |
Effects of Catecholamine Metabolites on Beta-Adrenoceptor-Mediated Relaxation of Smooth Muscle: Evaluation in Mouse and Guinea-Pig Trachea and Rat Aorta.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Aorta; Carbachol; Guinea Pigs; Isopr | 2020 |
A PPAR-α agonist protects the non-adrenergic, non-cholinergic inhibitory system of guinea pig trachea from the effect of inhaled ammonium persulphate: a pilot study.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Ammonium Sulfate; Animals; Electric Stimulatio | 2020 |
Cooperativity between β-agonists and c-Abl inhibitors in regulating airway smooth muscle relaxation.
Topics: Actin Cytoskeleton; Adrenergic beta-Agonists; Animals; Antineoplastic Agents; Benzamides; Drug Syner | 2021 |
Pharmacological identification of β-adrenoceptor subtypes mediating isoprenaline-induced relaxation of guinea pig colonic longitudinal smooth muscle.
Topics: Adrenergic beta-Agonists; Animals; Colon; Guinea Pigs; Isoproterenol; Male; Muscle Relaxation; Muscl | 2018 |
Connexin 43 Plays a Role in Pulmonary Vascular Reactivity in Mice.
Topics: Animals; Connexin 43; Endothelin-1; Female; Gap Junctions; Genotype; Hypertension, Pulmonary; Isopro | 2018 |
HCN as a Mediator of Urinary Homeostasis: Age-Associated Changes in Expression and Function in Adrenergic Detrusor Relaxation.
Topics: Adrenergic beta-Agonists; Animals; Female; Hyperpolarization-Activated Cyclic Nucleotide-Gated Chann | 2019 |
Quercetin acutely relaxes airway smooth muscle and potentiates β-agonist-induced relaxation via dual phosphodiesterase inhibition of PLCβ and PDE4.
Topics: Acetylcholine; Adrenergic beta-Agonists; Airway Resistance; Animals; Antioxidants; Blotting, Western | 2013 |
Do β-adrenoceptor agonists induce homologous or heterologous desensitization in rat urinary bladder?
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; | 2014 |
Mucosa of murine detrusor impairs β2 -adrenoceptor-mediated relaxation.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Agonists; Aminophenols; Animals; | 2015 |
Chloride channel blockade relaxes airway smooth muscle and potentiates relaxation by β-agonists.
Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Asthma; Cell Membrane; Chloride Channels; Chloride | 2014 |
β-Agonist-mediated relaxation of airway smooth muscle is protein kinase A-dependent.
Topics: Adrenergic beta-Agonists; Cell Line; Cyclic AMP-Dependent Protein Kinases; Guanine Nucleotide Exchan | 2014 |
Pyocyanin inhibits both nitric oxide-dependent and -independent relaxation in porcine coronary arteries.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Coronary Vessels; Cyclic AMP; Cyclic GMP | 2015 |
Relaxant effect of superimposed length oscillation on sensitized airway smooth muscle.
Topics: Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Fe | 2015 |
β-Adrenoceptor-Mediated Relaxation of Carbachol-Pre-Contracted Mouse Detrusor.
Topics: Aminophenols; Animals; Carbachol; Cholinergic Agonists; Colforsin; Homozygote; Imidazoles; Isoproter | 2015 |
Functional and molecular evidence for Kv7 channel subtypes in human detrusor from patients with and without bladder outflow obstruction.
Topics: Aged; Colforsin; Female; Gene Expression Regulation; Humans; Isoproterenol; KCNQ Potassium Channels; | 2015 |
The soluble guanylate cyclase stimulator riociguat and the soluble guanylate cyclase activator cinaciguat exert no direct effects on contractility and relaxation of cardiac myocytes from normal rats.
Topics: Animals; Benzoates; Calcium; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergis | 2015 |
Targeting integrin α5β1 ameliorates severe airway hyperresponsiveness in experimental asthma.
Topics: Animals; Asthma; Cell Adhesion; Cell Line; Chymases; Disease Models, Animal; Humans; Integrin alpha5 | 2017 |
Superimposed pressure oscillations: An alternative to treat airway hyperresponsiveness in an acute sensitized airways mouse model.
Topics: Acetylcholine; Acute Disease; Animals; Bronchodilator Agents; Disease Models, Animal; Female; Isopro | 2017 |
The endothelin receptor antagonist CPU0213 is more effective than aminoguanidine to attenuate isoproterenol-induced vascular abnormality by suppressing overexpression of NADPH oxidase [correction of oxidas], ETA, ETB, and MMP9 in the vasculature.
Topics: Animals; Aorta, Thoracic; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Guan | 2008 |
Beta-adrenergic relaxation of mouse urinary bladder smooth muscle in the absence of large-conductance Ca2+-activated K+ channel.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Re | 2008 |
Activation of endogenous GABAA channels on airway smooth muscle potentiates isoproterenol-mediated relaxation.
Topics: Acetylcholine; Adenosine Triphosphatases; Adrenergic beta-Agonists; Animals; Bronchoconstriction; Do | 2008 |
Catecholamines relax detrusor through beta 2-adrenoceptors in mouse and beta 3-adrenoceptors in man.
Topics: Aged; Animals; Catecholamines; Caveolin 1; DNA Primers; Epinephrine; Female; Humans; Isoproterenol; | 2009 |
L-carnitine treatment partially restores urinary bladder function of streptozotocin diabetic rats.
Topics: Adenosine; Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Autonomic Nervous System; Bloo | 2008 |
Prophylactic role of oral L-arginine on histological and contractile changes in a rat chronic bladder injury model.
Topics: Administration, Oral; Adrenergic beta-Agonists; Animals; Arginine; Carbachol; Cholinergic Agonists; | 2008 |
Potent bronchodilation and reduced stiffness by relaxant stimuli under dynamic conditions.
Topics: Analysis of Variance; Animals; Bronchoconstriction; Carbachol; Electric Stimulation; Isoproterenol; | 2009 |
Specific adrenergic responses of smooth muscles in the vascular wall of guinea pig pulmonary arteries during ovalbumin sensitization.
Topics: Adrenergic beta-Agonists; Animals; Guinea Pigs; In Vitro Techniques; Isoproterenol; Isotonic Solutio | 2008 |
Effects of a novel beta(3)-adrenoceptor agonist, AJ-9677, on relaxation of the detrusor muscle: an in vitro study.
Topics: Acetates; Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Animals; Dioxoles; Female; Human | 2008 |
Thromboxane prostanoid receptor activation impairs endothelial nitric oxide-dependent vasorelaxations: the role of Rho kinase.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bronchodilator Agents; | 2009 |
Effect of pre-contraction on β-adrenoceptor-mediated relaxation of rat urinary bladder.
Topics: Adrenergic beta-Agonists; Animals; Bradykinin; Carbachol; Colforsin; Dose-Response Relationship, Dru | 2009 |
Esophageal and gastric smooth muscle activity after carbon dioxide pneumoperitoneum.
Topics: Abdomen; Animals; Carbachol; Carbon Dioxide; Esophagus; Isoproterenol; Laparotomy; Muscle Contractio | 2010 |
Alteration of airway responsiveness mediated by receptors in ovalbumin-induced asthmatic E3 rats.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchodilator Agents; Dose-Response Relationship, Drug; | 2009 |
β-Adrenoceptor-mediated differences in transverse and longitudinal strips from the rat detrusor.
Topics: Adrenergic beta-Agonists; Animals; Female; Isoproterenol; Male; Muscle Contraction; Muscle Relaxatio | 2011 |
Pre-treatment with α-hederin increases β-adrenoceptor mediated relaxation of airway smooth muscle.
Topics: Adrenergic beta-Agonists; Animals; Bronchodilator Agents; Cattle; Drug Synergism; Hedera; Histamine; | 2011 |
Epac as a novel effector of airway smooth muscle relaxation.
Topics: Animals; Cell Adhesion Molecules; Cells, Cultured; Cyclic AMP; Guanine Nucleotide Exchange Factors; | 2011 |
Design, synthesis and in vitro evaluation of (R)-4-(2-(tert-butylamino)-1-hydroxyethyl)-2-(hydroxymethyl)phenyl hydrogen phenylboronate: a novel salbutamol derivative with high intrinsic efficacy on the β2 adrenoceptor.
Topics: Adrenergic beta-2 Receptor Agonists; Albuterol; Animals; Binding Sites; Computer Simulation; Drug De | 2010 |
Novel expression of a functional glycine receptor chloride channel that attenuates contraction in airway smooth muscle.
Topics: Acetylcholine; Animals; Cells, Cultured; Cesium; Chlorides; Electrophysiology; Glycine; Guinea Pigs; | 2011 |
[Establishment of isolated rabbit airway smooth muscles responsiveness model for the pharmacodynamic study of anti-rhinoviruses drugs].
Topics: Acetylcholine; Animals; Antiviral Agents; Cytopathogenic Effect, Viral; HeLa Cells; Humans; Isoprote | 2010 |
Effect of bitter tastants on human bronchi.
Topics: Bronchi; Bronchoconstriction; Dose-Response Relationship, Drug; Humans; Isoproterenol; Methacholine | 2011 |
Bronchodilator activity of bitter tastants in human tissue.
Topics: Animals; Bronchi; Bronchodilator Agents; Chloroquine; Dose-Response Relationship, Drug; Guinea Pigs; | 2011 |
Carbon dioxide enhances substance P-induced epithelium-dependent bronchial smooth muscle relaxation in Sprague-Dawley rats.
Topics: Animals; Bronchi; Calcium; Carbon Dioxide; Drug Synergism; Epithelium; Hydrogen-Ion Concentration; H | 2011 |
Muscarinic receptor subtypes and signalling involved in the attenuation of isoprenaline-induced rat urinary bladder relaxation.
Topics: Adrenergic beta-Agonists; Animals; Carbachol; Isoproterenol; Male; Muscarinic Agonists; Muscarinic A | 2011 |
Effects of marmin, a compound isolated from Aegle marmelos Correa, on contraction of the guinea pig-isolated trachea.
Topics: Aegle; Animals; Calcium Chloride; Coumarins; Guinea Pigs; Histamine; In Vitro Techniques; Isoprotere | 2011 |
Influence of influenza A infection on capsaicin-induced responses in murine airways.
Topics: Animals; Biphenyl Compounds; Bronchoalveolar Lavage Fluid; Capsaicin; Carbachol; Cyclooxygenase Inhi | 2012 |
Relaxant and contractile responses of detrusor muscle strips obtained from bladder outlet-obstructed rats treated with doxazosin enantiomers.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Agonists; Animals; Carbachol; Cholinergic A | 2011 |
Loss of adenosine A2B receptor mediated relaxant responses in the aged female rat bladder; effects of dietary phytoestrogens.
Topics: Adenosine-5'-(N-ethylcarboxamide); Adrenergic beta-Agonists; Aging; Animals; Carbachol; Diet; Estrog | 2012 |
Smooth muscle pharmacology in the isolated virgin and pregnant rat uterus and cervix.
Topics: Actins; Adrenergic beta-Agonists; Animals; Carbachol; Cervix Uteri; Cholinergic Agonists; Colforsin; | 2012 |
Isometric responses of isolated intrapulmonary bronchioles from cats with and without adult heartworm infection.
Topics: Acetylcholine; Animals; Bronchioles; Bronchodilator Agents; Cat Diseases; Cats; Dirofilaria immitis; | 2012 |
Bladder selectivity of the novel β₃-agonist ritobegron (KUC-7483) explored by in vitro and in vivo studies in the rat.
Topics: Acetates; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-3 Receptor Antagonists; Adrenergic be | 2012 |
TAS2R activation promotes airway smooth muscle relaxation despite β(2)-adrenergic receptor tachyphylaxis.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Chloroquine; Humans; In Vitro Techniques; Isoprotereno | 2012 |
Comparative study of the quercetin, ascorbic acid, glutathione and superoxide dismutase for nitric oxide protecting effects in mouse gastric fundus.
Topics: Aminoquinolines; Animals; Antioxidants; Ascorbic Acid; Ditiocarb; Female; Gastric Fundus; Glutathion | 2013 |
A putative role for S-nitrosoglutathione as the source of nitric oxide in photorelaxation of the mouse gastric fundus.
Topics: Acetylcysteine; Animals; Cysteine; Diamide; Enzyme Inhibitors; Ethacrynic Acid; Female; Gastric Fund | 2002 |
Muscarinic M2 receptors in acetylcholine-isoproterenol functional antagonism in human isolated bronchus.
Topics: Acetylcholine; Bronchi; Colforsin; Cyclic AMP; Humans; In Vitro Techniques; Isoproterenol; Lung Neop | 2002 |
Uncoupling protein-1: involvement in a novel pathway for beta-adrenergic, cAMP-mediated intestinal relaxation.
Topics: Adrenergic beta-Agonists; Animals; Animals, Outbred Strains; Carrier Proteins; Cyclic AMP; Electric | 2002 |
Effect of hypothyroidism on beta-adrenoceptor-mediated relaxation in the rat thoracic aortae. A time-dependent study.
Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Antithyroid Agents; Aorta, Thoracic; Endothelium, | 2002 |
Effects of direct and indirect activation of G protein of adenylyl cyclase on the subsequent response to beta-adrenergic receptor agonists in human trachealis.
Topics: Adrenergic beta-Agonists; Aged; Aged, 80 and over; Bronchoconstrictor Agents; Cholera Toxin; Enzyme | 2002 |
Inhibitory effect of beta3-adrenoceptor agonist in lower esophageal sphincter smooth muscle: in vitro studies.
Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aminophe | 2003 |
Functional development of the rat urinary bladder after pre- or postpubertal castration.
Topics: Adenosine Triphosphate; Animals; Carbachol; Dose-Response Relationship, Drug; Female; In Vitro Techn | 2003 |
5-HT7 receptor-mediated relaxation of the oviduct in nonpregnant proestrus pigs.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Binding, Competitive; Cyclic AMP; Dose-Response Relati | 2003 |
Evidence for the primary role for 4-aminopyridine-sensitive K(v) channels in beta(3)-adrenoceptor-mediated, cyclic AMP-independent relaxations of guinea-pig gastrointestinal smooth muscles.
Topics: 4-Aminopyridine; Adrenergic Agonists; Animals; Catecholamines; Cyclic AMP; Epinephrine; Ethanolamine | 2003 |
Exercise restores beta-adrenergic vasorelaxation in aged rat carotid arteries.
Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Blotting, Western; Body Weight; Brimonidine Tartra | 2003 |
Muscarinic blockers potentiate beta-adrenergic relaxation of bovine iris sphincter.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Cattle; Dose-Response Relationship, Drug; Drug Synergi | 2003 |
Augmentation of rat urinary bladder relaxation mediated by beta1-adrenoceptors in experimental diabetes.
Topics: Adrenergic beta-Agonists; Animals; Colforsin; Diabetes Mellitus, Experimental; In Vitro Techniques; | 2003 |
Role of nitric oxide in beta3-adrenoceptor activation on basal tone of internal anal sphincter.
Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-3 Receptor Antagonists; Adrenergic beta-Agonist | 2003 |
Isoprenaline and aminophylline relax bronchial smooth muscle by cAMP-induced stimulation of large-conductance Ca2+-activated K+ channels.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aminophylline; Animals; Bronchi; Bronchodilator Agents; In V | 2003 |
Functional response of bladder strips from streptozotocin diabetic rats depends on bladder mass.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Diabetes Mellitus, Experimental; Elect | 2003 |
Role of beta-adrenoceptor subtypes in mediating relaxation of the pig bladder trigonal muscle in vitro.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Dose-Response Relationshi | 2003 |
Evaluation of beta3-adrenoceptor-mediated relaxation in intact and endotoxin-treated equine digital veins.
Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-3 Receptor Antagonists; Animals; Dose-Response | 2003 |
Functional characterization of beta-adrenoceptor subtypes in the canine and rat lower urinary tract.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Dioxoles; Dobutamine; Dogs; Female; | 2003 |
Function of beta1-adrenoceptors and mRNA expression of beta1- and beta2-adrenoceptors in guinea-pig esophagus.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Esophagus; Guinea Pigs; In Vitro Tec | 2003 |
Age-related smooth muscle reactivity changes in the rat bladder: an in vitro study.
Topics: Adenosine Triphosphate; Aging; Animals; Carbachol; Dose-Response Relationship, Drug; In Vitro Techni | 2003 |
The influence of epithelium on the responsiveness of guinea-pig trachea to -adrenergic agonist and antagonist.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Asthma; Dose-Response Relationship, | 2003 |
Enhanced myosin phosphatase and Ca(2+)-uptake mediate adrenergic relaxation of airway smooth muscle.
Topics: Adrenergic beta-Agonists; Animals; Bronchi; Bronchodilator Agents; Calcium; Calcium-Transporting ATP | 2004 |
Endothelin-1 limits vascular smooth muscle beta-adrenergic receptor sensitivity by a PKC-dependent pathway.
Topics: Alkaloids; Animals; Aorta, Thoracic; Benzophenanthridines; Colforsin; Cyclosporine; Endothelin Recep | 2003 |
The effects of selective phosphodiesterase III and V inhibitors on adrenergic and non-adrenergic, non-cholinergic relaxation responses of guinea-pig pulmonary arteries.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine; Animals; Argini | 2003 |
Effects of ouabain on human bronchial muscle in vitro.
Topics: Acetylcholine; Bronchi; Calcium; Calcium Channel Blockers; Colforsin; Cromakalim; Histamine; Humans; | 2003 |
The functional role of beta-adrenoceptor subtypes in mediating relaxation of pig urethral smooth muscle.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Ethanolamines; Female; Im | 2003 |
MaxiK channel mediates beta2-adrenoceptor-activated relaxation to isoprenaline through cAMP-dependent and -independent mechanisms in guinea-pig tracheal smooth muscle.
Topics: Adrenergic beta-Agonists; Animals; Cyclic AMP; Female; GTP-Binding Protein alpha Subunits, Gs; Guine | 2003 |
Beta1-adrenoceptor-mediated relaxation with isoprenaline and the role of MaxiK channels in guinea-pig esophageal smooth muscle.
Topics: Adrenergic beta-Agonists; Animals; Esophagus; Female; Guinea Pigs; Isoproterenol; Large-Conductance | 2004 |
Daidzein and 17 beta-estradiol enhance nitric oxide synthase activity associated with an increase in calmodulin and a decrease in caveolin-1.
Topics: Acetylcholine; Animals; Aorta; Body Weight; Calmodulin; Caveolin 1; Caveolins; Cyclic GMP; Drug Syne | 2004 |
The effect of the indomethacin on phosphodiesterase inhibitors mediated responses in isolated trachea preparations.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Guinea Pigs; Histamine; In Vitro Techniques; Indom | 2004 |
Beta3-adrenoceptors: relaxant function and mRNA detection in smooth muscle cells isolated from the human colon.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Colon; Gastrointestinal Motility; Humans; Imi | 2004 |
Evidence showing that beta-adrenoceptor subtype responsible for the relaxation induced by isoprenaline is principally beta 2 but not beta 1 in guinea-pig tracheal smooth muscle.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Animals; Female; Guinea Pi | 2004 |
Does cyclic AMP mediate rat urinary bladder relaxation by isoproterenol?
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenine; Adenylyl Cyclase Inhibitors; Adrenergic beta | 2005 |
The M2 muscarinic receptor mediates contraction through indirect mechanisms in mouse urinary bladder.
Topics: Adrenergic beta-Agonists; Animals; Binding, Competitive; Colforsin; Dinoprost; Diphenylacetic Acids; | 2005 |
Evidence for the presence of beta-3-adrenoceptors mediating relaxation in the human oviduct.
Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-3 Receptor Antagonists; Adult; Dose-Response Re | 2005 |
Beta-adrenoceptor-mediated vascular relaxation in spontaneously hypertensive rats.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Dose-Response Relat | 2005 |
Functional changes in adenylyl cyclases and associated decreases in relaxation responses in mesenteric arteries from diabetic rats.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Blood Glucose; Body Weight; Colforsin; Cyclic | 2005 |
Potentiation of beta-adrenoceptor function in bovine tracheal smooth muscle by inhibition of protein kinase C.
Topics: Adrenergic beta-Agonists; Animals; Cattle; Colforsin; Dose-Response Relationship, Drug; Drug Synergi | 2005 |
Lack of inotropic effect of nitric oxide on the rat myocardium.
Topics: Adrenergic beta-Agonists; Animals; Hypoxia; In Vitro Techniques; Isoproterenol; Male; Muscle Contrac | 2005 |
Involvement of cyclic AMP-dependent and -independent mechanisms in the relaxation of rat detrusor muscle via beta-adrenoceptors.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Adrenergic beta-Agonists; Animals; Benzocycloheptenes; Clenbut | 2005 |
Relaxant effects of beta-adrenergic agonists on porcine and human detrusor muscle.
Topics: Adrenergic beta-Agonists; Aged; Albuterol; Animals; Dioxoles; Dose-Response Relationship, Drug; Epin | 2005 |
Overexpression of junctin causes adaptive changes in cardiac myocyte Ca(2+) signaling.
Topics: Adaptation, Physiological; Animals; Calcium Signaling; Calcium-Binding Proteins; Calcium-Transportin | 2006 |
Protein kinase C potentiates homologous desensitization of the beta2-adrenoceptor in bovine tracheal smooth muscle.
Topics: Adrenergic beta-Agonists; Animals; Cattle; Dose-Response Relationship, Drug; Fenoterol; In Vitro Tec | 2006 |
Benzisothiazoles and beta-adrenoceptors: synthesis and pharmacological investigation of novel propanolamine and oxypropanolamine derivatives in isolated rat tissues.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-3 Re | 2005 |
Airway smooth muscle relaxation results from a reduction in the frequency of Ca2+ oscillations induced by a cAMP-mediated inhibition of the IP3 receptor.
Topics: Animals; Calcium Channels; Calcium Signaling; Cyclic AMP; Inositol 1,4,5-Trisphosphate Receptors; Is | 2006 |
Effects of gender, age and hypertension on beta-adrenergic receptor function in rat urinary bladder.
Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Age Factors; Animals; Ethanolamines; | 2006 |
Effects of 138-355, a beta3-adrenoceptor selective agonist, on relaxation of the human detrusor muscle in vitro.
Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albutero | 2006 |
Purinergic nerves mediate the non-nitrergic relaxation of the human ileum in response to electrical field stimulation.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Electric Stimulation; Enteric Nervous System; Enzy | 2006 |
Mechanisms of relaxant action of a crude hexane extract of Gnaphalium liebmannii in guinea pig tracheal smooth muscle.
Topics: Aminophylline; Animals; Bronchodilator Agents; Colforsin; Dose-Response Relationship, Drug; Gnaphali | 2007 |
[Involvement of adenylyn cyclase signaling mechanisms in relaxing effect of relaxin and insulin on the rat uterus, trachea and human myometrium].
Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Female; Humans; Insulin; Isoproterenol; Muscle Contraction; | 2006 |
Studies on the mechanisms underlying beta-adrenoceptor-mediated relaxation of rat abdominal aorta.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Aorta, Abdominal; Cyclic AMP; In Vit | 2006 |
Relaxation of human detrusor muscle by selective beta-2 and beta-3 agonists and endogenous catecholamines.
Topics: Adrenergic beta-Agonists; Aged; Catecholamines; Clenbuterol; Dose-Response Relationship, Drug; Ethan | 2007 |
Effect of chronic renal failure on foregut smooth muscle reactivity: an experimental study.
Topics: Adrenergic beta-Agonists; Animals; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug | 2007 |
Role of beta-3-adrenoceptor in catecholamine-induced relaxations in gastric fundus from control and diabetic rats.
Topics: Animals; Catecholamines; Diabetes Mellitus, Experimental; Ethanolamines; Fenoterol; Gastric Fundus; | 2007 |
Serotonin responsiveness through 5-HT2A and 5-HT4 receptors is differentially regulated in hypertrophic and failing rat cardiac ventricle.
Topics: Animals; Echocardiography; Gene Expression Regulation; Heart Failure; Heart Ventricles; Humans; Hype | 2007 |
The small heat shock-related protein, HSP20, is a cAMP-dependent protein kinase substrate that is involved in airway smooth muscle relaxation.
Topics: Animals; Cattle; Colforsin; Cyclic AMP-Dependent Protein Kinases; HSP20 Heat-Shock Proteins; Isoprot | 2008 |
In vitro sensitivity of mouse esophagus to agonists in different pH medium values.
Topics: Acetylcholine; Adrenergic beta-Agonists; Analysis of Variance; Animals; Carbachol; Cholinergic Agoni | 2007 |
Heme oxygenase-1 induction depletes heme and attenuates pulmonary artery relaxation and guanylate cyclase activation by nitric oxide.
Topics: Acridines; Adrenergic beta-Agonists; Animals; Blotting, Western; Cattle; Cobalt; Enzyme Activation; | 2008 |
Relaxations to beta-adrenoceptor subtype selective agonists in wild-type and NOS-3-KO mouse mesenteric arteries.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Recep | 2008 |
O2-sensitivity of beta adrenergic responsiveness in isolated bovine and porcine coronary arteries.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cattle; Coronary Vessels; Dose-Response Relationship, | 1984 |
Stimulant and blocking effects of optical isomers of pindolol on the sinoatrial node and trachea of guinea pig. Role of beta-adrenoceptor subtypes in the dissociation between blockade and stimulation.
Topics: Animals; Bupranolol; Cimetidine; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Isoproterenol | 1984 |
Effects of isoprenaline on the contraction-relaxation cycle in the cat trachea.
Topics: Acetylcholine; Animals; Caffeine; Calcium; Cats; Cyclic AMP; Female; In Vitro Techniques; Isoprotere | 1984 |
Alteration of cytoplasmic ionized calcium levels in smooth muscle by vasodilators in the ferret.
Topics: Aequorin; Animals; Calcium; Carnivora; Cyclic AMP; Cytoplasm; Female; Ferrets; In Vitro Techniques; | 1984 |
Peripheral vascular smooth muscle relaxation in normotensive and hypertensive rats.
Topics: Adenosine; Animals; Desoxycorticosterone; Hypertension; Isoproterenol; Male; Mesenteric Arteries; Mu | 1980 |
The potentiating effect of an alpha-adrenergic blocking agent (E-643) on the action of bronchodilators.
Topics: Adrenergic alpha-Antagonists; Animals; Bronchodilator Agents; Cyclic AMP; Cyclic GMP; Drug Synergism | 1980 |
Alpha- and beta-adrenoceptor blockade by labetalol in human isolated arteries and veins.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Arteries; Ethanolamines; Guinea | 1980 |
Tachyphylaxis to beta-adrenoceptor agonists in human bronchial smooth muscle: studies in vitro.
Topics: Adrenergic beta-Agonists; Airway Resistance; Bronchi; Cyclic AMP; Drug Interactions; Humans; In Vitr | 1980 |
The oil immersion technique for studying the disposition of drugs inducing relaxation; influence of U-0521 and hydrocortisone on the disposition of isoprenaline.
Topics: Animals; Dogs; Dose-Response Relationship, Drug; Hydrocortisone; In Vitro Techniques; Isoproterenol; | 1980 |
Impairment of pharmacological modulation of airways smooth muscle by a respiratory pathogen.
Topics: Airway Resistance; Animals; Bacterial Vaccines; Carbachol; Dimaprit; Haemophilus; Histamine; Isoprot | 1981 |
Demonstration of both beta 1- and beta 2-adrenoceptors mediating relaxation of isolated ring preparations of rat pulmonary artery.
Topics: Adrenergic beta-Agonists; Animals; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Mus | 1981 |
On the ability of domperidone to selectively inhibit catecholamine-induced relaxation of circular smooth muscle of guinea-pig stomach.
Topics: Animals; Catecholamines; Domperidone; Dopamine; Guinea Pigs; In Vitro Techniques; Isoproterenol; Mal | 1982 |
Bordetella pertussis-induced impairment of relaxation of rat trachea to isoprenaline and histamine and its reversal with hydrocortisone.
Topics: Animals; Carbachol; Histamine; Histamine H2 Antagonists; Hydrocortisone; Isoproterenol; Male; Muscle | 1982 |
Denervation and beta-adrenoreceptors of the cat nictitating membrane.
Topics: Adrenergic beta-Antagonists; Albuterol; Animals; Cats; Epinephrine; Female; In Vitro Techniques; Iso | 1981 |
[Studies on the blood pressure of beta-adrenoceptor blocking drugs, particularly in relation to the mechanism of the pressor action induced by beta-adrenoceptor blocking drugs in rats (author's transl)].
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Female; Guinea Pigs; Heart Atria; Heart Rate; | 1982 |
Effect of drug-induced tone on the ability of histamine H2 receptor agonists to relax guinea-pig tracheal chain.
Topics: Animals; Dimaprit; Guanidines; Guinea Pigs; Imidazoles; Impromidine; In Vitro Techniques; Isoprotere | 1982 |
Relaxation of cat trachea by beta-adrenoceptor agonists can be mediated by both beta1- and beta2-adrenoceptors and potentiated by inhibitors of extraneuronal uptake.
Topics: Adrenergic beta-Agonists; Airway Resistance; Animals; Atenolol; Cats; Drug Synergism; Female; In Vit | 1983 |
Role of cyclic AMP in adrenergically-induced tracheal muscle relaxation.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Airway Resistance; | 1983 |
Relationship between intrinsic activity of beta-adrenoceptor agonist and amount of spare receptors in guinea pig taenia caecum.
Topics: Adrenergic beta-Agonists; Affinity Labels; Animals; Carteolol; Cecum; Cyclic AMP; Dose-Response Rela | 1983 |
The role of myosin light chain kinase phosphorylation in beta-adrenergic relaxation of tracheal smooth muscle.
Topics: Adrenergic beta-Agonists; Animals; Carbachol; Cattle; Cyclic AMP; In Vitro Techniques; Isoproterenol | 1983 |
[Sequence of steroid enhancement of relaxation of the guinea pig tracheal muscle by beta-adrenergic stimulants].
Topics: Adrenergic beta-Agonists; Animals; Drug Synergism; Glucocorticoids; Guinea Pigs; In Vitro Techniques | 1983 |
Relaxation of cat tracheobronchial and pulmonary arterial smooth muscle by vasoactive intestinal peptide: lack of influence by peptidase inhibitors.
Topics: Airway Resistance; Animals; Bethanechol Compounds; Bronchi; Cats; Female; In Vitro Techniques; Isopr | 1984 |
Desensitization of smooth muscle and mast cell beta-adrenoceptors in the airways of the guinea pig.
Topics: Adrenergic alpha-Agonists; Albuterol; Animals; Clenbuterol; Dose-Response Relationship, Drug; Fenote | 1984 |
Synthesis of a novel series of (aryloxy)propanolamines: new selective beta 2-blocking agents.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Guinea Pigs; Heart Rate; Isoproterenol; Muscle | 1984 |
Effect of dopamine on dog distal colon in-vitro.
Topics: Animals; Colon; Dogs; Dopamine; Dose-Response Relationship, Drug; Epinephrine; In Vitro Techniques; | 1984 |
Is there any evidence of beta 1-adrenoceptors mediating relaxation of guinea-pig lung parenchyma?
Topics: Adrenergic beta-Antagonists; Animals; Ethanolamines; Guinea Pigs; In Vitro Techniques; Isoproterenol | 1984 |
Synthesis and beta-adrenergic blocking activity of new aliphatic and alicyclic oxime ethers.
Topics: Adrenergic beta-Antagonists; Animals; Ethers; Guinea Pigs; Heart Rate; Indicators and Reagents; Isop | 1984 |
Characterization of beta-adrenoceptors mediating relaxation of the guinea-pig ileum.
Topics: Albuterol; Animals; Electric Stimulation; Female; Guinea Pigs; Heart; Ileum; In Vitro Techniques; Is | 1984 |
Cyclic AMP-dependent and -independent effects of beta-adrenergic stimulation on the contraction-relaxation cycle of spontaneously beating rat atria.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Calcium; Cyclic AMP; Heart Atria; Io | 1982 |
Parathyroid hormone (PTH) fragments relax the guinea-pig trachea in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Female; Guinea Pigs; Hydrogen Peroxide; Imidazoles; In Vitro T | 1983 |
Effects of formoterol (BD 40A), a beta-adrenoceptor stimulant, on isolated guinea-pig lung parenchymal strips and antigen-induced SRS-A release in rats.
Topics: Adrenergic beta-Agonists; Airway Resistance; Albuterol; Anaphylaxis; Animals; Cromolyn Sodium; Ethan | 1984 |
Differentiation of functional adrenoceptors in human and guinea pig airways.
Topics: Anaphylaxis; Animals; Bronchi; Corticosterone; Guinea Pigs; Histamine Release; Humans; Immunization; | 1984 |
[Parathyroid hormone fragments relax guinea pig trachea in vitro].
Topics: 1-Methyl-3-isobutylxanthine; Animals; Female; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; | 1984 |
Effect of norepinephrine and isoproterenol on in vitro detrusor muscle contractility and cyclic AMP content.
Topics: Animals; Cyclic AMP; Dogs; Female; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Mus | 1980 |
Effect of Bordetella pertussis vaccination in mice and the isolated tracheal response to isoprenaline.
Topics: Animals; Asthma; Bordetella pertussis; Carbachol; Histamine; Injections, Intraperitoneal; Isoprotere | 1980 |
Relaxation of vascular smooth muscle by isoproterenol, dibutyryl-cyclic AMP and theophylline.
Topics: Animals; Arteries; Bucladesine; Cats; Dogs; Female; In Vitro Techniques; Isoproterenol; Male; Muscle | 1981 |
Coupling of beta-adrenoreceptors in rat uterine smooth muscle.
Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Dihydroalprenolol; Female; Guanylyl Imidodiphosphate; Isopro | 1981 |
Alpha- and beta-adrenergically mediated responses in isolated lung strips of guinea pigs.
Topics: Animals; Cocaine; Guinea Pigs; In Vitro Techniques; Isoproterenol; Lung; Muscle Contraction; Muscle | 1981 |
Tolerance of guinea-pig airway muscle preparations to relaxant agonists induced by chronic exposure to isoprenaline in vivo.
Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Female; Guinea Pigs; Histamine; In Vitro | 1981 |
Effect of isoprenaline on dopamine receptors in the rabbit isolated renal artery.
Topics: Animals; Aorta; Dopamine; Haloperidol; Isoproterenol; Muscle Relaxation; Muscle, Smooth, Vascular; P | 1981 |
Age-related decrease of in vitro isoproterenol-induced cyclic AMP accumulation in rat aorta.
Topics: Aging; Animals; Aorta, Thoracic; Arteries; Cyclic AMP; DNA; Isoproterenol; Male; Muscle Relaxation; | 1982 |
Beta-receptors during aging in respiratory tissues.
Topics: Aging; Animals; Benzyl Alcohols; Bronchi; Female; Guinea Pigs; Histamine; Isoproterenol; Muscle Rela | 1982 |
Temperature dependence if beta-receptor mediated relaxation in rabbit intestine.
Topics: Animals; Cyclic AMP; Dihydroalprenolol; Female; In Vitro Techniques; Intestines; Isoproterenol; Male | 1982 |
Mechanisms of relaxation induced by activation of beta-adrenoceptors in smooth muscle cells of the guinea-pig mesenteric artery.
Topics: Animals; Caffeine; Calcium; Cyclic AMP; Female; Guinea Pigs; In Vitro Techniques; Isoproterenol; Mal | 1982 |
Analysis of the beta 1 and beta 2 adrenoceptor interactions of the partial agonist, clenbuterol (NAB365), in the rat jugular vein and atria.
Topics: Animals; Clenbuterol; Ethanolamines; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Jugular | 1982 |
Effects of beta-adrenergic stimulation on calcium movements in rabbit aortic smooth muscle: relationship with cyclic AMP.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Aorta; Biological Transport; Bucladesine; C | 1982 |
Trimetaquinol relaxes bovine pulmonary arteries in vitro through a non-beta-adrenergic mechanism.
Topics: Animals; Cattle; Isoproterenol; Isoquinolines; Muscle Contraction; Muscle Relaxation; Muscle, Smooth | 1981 |
Desensitization of beta-adrenoreceptors in guinea-pig trachea: a prostaglandin mediated phenomenon.
Topics: Animals; Drug Resistance; Guinea Pigs; Humans; Indomethacin; Isoproterenol; Male; Muscle Relaxation; | 1982 |
Effect of steroids on beta-adrenoceptor-mediated relaxation of pig bronchus.
Topics: Airway Resistance; Animals; Bronchi; Catecholamines; Estradiol; Fenoterol; In Vitro Techniques; Isop | 1983 |
Potentiation of the effects of sodium nitroprusside and of isoproterenol by selective phosphodiesterase inhibitors.
Topics: Animals; Calmodulin; Cattle; Chromatography, DEAE-Cellulose; Coronary Vessels; Cyclic AMP; Cyclic GM | 1983 |
Desensitization of beta-adrenoceptor in guinea pig trachea: a link with the prostaglandin system.
Topics: Animals; Bronchi; Dinoprostone; Guinea Pigs; Humans; Indomethacin; Isoproterenol; Male; Muscle Contr | 1983 |
Regional variation in beta adrenergic receptors in dog trachea: correlation of receptor density and in vitro relaxation.
Topics: Animals; Dinoprostone; Dogs; Iodocyanopindolol; Isoproterenol; Kinetics; Muscle Contraction; Muscle | 1983 |
Classification of beta-adrenoceptors in isolated bronchus of the pig.
Topics: Animals; Atenolol; Bronchi; Catechols; Drug Interactions; Epinephrine; In Vitro Techniques; Isoprote | 1983 |
Supersensitivity in the isolated urethra of the rat following "chemical sympathectomy".
Topics: Animals; Drug Hypersensitivity; Hydroxydopamines; In Vitro Techniques; Isoproterenol; Male; Muscle C | 1983 |
Comparison of the effects of forskolin and isoproterenol on cyclic AMP levels and tension in bovine coronary artery.
Topics: Animals; Cattle; Colforsin; Cyclic AMP; Diterpenes; Isoproterenol; Muscle Contraction; Muscle Relaxa | 1983 |
Hydrocortisone and isoproterenol effects on trachealis cAMP and relaxation.
Topics: Analysis of Variance; Animals; Cyclic AMP; Cyclic GMP; Dogs; Hydrocortisone; In Vitro Techniques; Is | 1983 |
Beta-adrenoceptor heterogeneity in guinea-pig airways: comparison of functional and receptor labelling studies.
Topics: Animals; Binding, Competitive; Bronchi; Dihydroalprenolol; Guinea Pigs; In Vitro Techniques; Iodocya | 1983 |
Hyperreactive airway smooth muscle responsiveness after inhalation of toluene diisocyanate vapors.
Topics: Animals; Carbachol; Cyanates; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Is | 1984 |
Effects of cinepazide on the purinergic responses in the dog cerebral artery.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cerebral Arteries; Cyclic AMP; Dogs; Drug Interactions; | 1984 |
Mouse uterine muscle as a model for studying beta 2-adrenoreceptor mediated relaxation.
Topics: Animals; Clonidine; Epinephrine; Estrus; Female; In Vitro Techniques; Isoproterenol; Mice; Models, B | 1984 |
The potential bronchodilator action of verapamil.
Topics: Animals; Barium; Barium Compounds; Bronchi; Chlorides; Dinoprost; Dose-Response Relationship, Drug; | 1984 |
Coronary artery reactivity in deoxycorticosterone acetate hypertensive rats.
Topics: Acetylcholine; Adenosine; Animals; Arteries; Coronary Vessels; Desoxycorticosterone; Epoprostenol; H | 1984 |
Endothelium-dependent relaxation of rabbit aorta. II. Inhibition of relaxation stimulated by methacholine and A23187 with antagonists of arachidonic acid metabolism.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Anti-Bacterial Agents; Aorta, Thoracic; Arachidonic Acid; | 1983 |
Bronchodilator-mediated relaxation of normal and ovalbumin-sensitized guinea-pig airways: lack of correlation with lung adenylate cyclase activation.
Topics: Adenylyl Cyclases; Animals; Bronchodilator Agents; Colforsin; Cyclooxygenase Inhibitors; Dinoproston | 1984 |
Effect of vasoactive intestinal peptide on vagally mediated tracheal pouch relaxation.
Topics: Animals; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Contrac | 1984 |
Influence of pH on the responses of guinea-pig isolated trachea to sympathomimetic amines.
Topics: Animals; Epinephrine; Female; Guinea Pigs; Hydrogen-Ion Concentration; In Vitro Techniques; Isoprote | 1984 |
[A study on the mechanism of the potentiating effects of glucocorticoids on the relaxing activity of isoproterenol in guinea-pig tracheal smooth muscle].
Topics: Animals; Bronchi; Cycloheximide; Dexamethasone; Drug Synergism; Guinea Pigs; In Vitro Techniques; Is | 1983 |
Comparison of vasoactive intestinal peptide and isoproterenol relaxant effects in isolated cat airways.
Topics: Animals; Bronchi; Cats; Dose-Response Relationship, Drug; Female; Indomethacin; Isoproterenol; Male; | 1984 |
Higher sensitivity of cerebral arteries isolated from premature and newborn baboons to adrenergic and cholinergic stimulation.
Topics: Acetylcholine; Aging; Animals; Animals, Newborn; Cerebral Arteries; Female; Gestational Age; In Vitr | 1984 |
The relaxing effect of caerulein on isolated human internal anal sphincter.
Topics: Acetylcholine; Anal Canal; Atropine; Ceruletide; Humans; In Vitro Techniques; Isoproterenol; Muscle | 1983 |
Relaxant action of VIP on cat pulmonary artery: comparison with acetylcholine, isoproterenol, and PGE1.
Topics: Acetylcholine; Animals; Cats; Female; Gastrointestinal Hormones; Isoproterenol; Male; Muscle Contrac | 1983 |
Human metabolism of 7-substituted theophyllines: N3-demethylation and lack of oxidation of proxyphylline.
Topics: Aminophylline; Animals; Biotransformation; Dealkylation; Guinea Pigs; Humans; In Vitro Techniques; I | 1981 |
Equine influenza virus enhances responsiveness of guinea-pig tracheal muscle to isoprenaline.
Topics: Animals; Carbachol; Drug Interactions; Guinea Pigs; In Vitro Techniques; Influenza A virus; Isoprote | 1982 |
Characterization of the rat basilar artery in vitro.
Topics: Animals; Basilar Artery; Cerebrovascular Circulation; Isoproterenol; Male; Muscle Contraction; Muscl | 1982 |
Effects of Freund's complete adjuvant and ovalbumin sensitization on the pharmacological reactivity of isolated guinea-pig trachea.
Topics: Animals; Carbachol; Freund's Adjuvant; Guinea Pigs; Histamine; Immunization; In Vitro Techniques; Is | 1982 |
[Relaxing effect of isoprenaline on the contracture of the guinea-pig taenia coli].
Topics: Animals; Colon; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Ions; Isoprotere | 1982 |
Analysis of relaxant effects of trapidil in isolated dog coronary artery.
Topics: Acetylcholine; Animals; Coronary Vessels; Dogs; Drug Interactions; Female; In Vitro Techniques; Isop | 1980 |
Relative contracting and relaxing potencies of a series of prostaglandins on isolated canine mesenteric artery strips.
Topics: Animals; Biological Assay; Dogs; Isoproterenol; Mesenteric Arteries; Muscle Contraction; Muscle Rela | 1981 |
Influence of tracheal contraction on relaxant effects in vitro of theophylline and isoprenaline.
Topics: Airway Resistance; Animals; Carbachol; Drug Interactions; Female; Guinea Pigs; Hydrogen-Ion Concentr | 1981 |
Effect of inotropic interventions on rate of change of ventricular diastolic dimensions.
Topics: Animals; Blood Pressure; Diastole; Dogs; Heart Ventricles; Isoproterenol; Muscle Relaxation; Myocard | 1981 |
[Bronchodilator actions of diltiazem in vitro and in vivo (author's transl)].
Topics: Animals; Benzazepines; Bronchi; Bronchodilator Agents; Calcium; Cats; Diltiazem; Dogs; Female; Guine | 1981 |
Quantitization of Ca spike frequency in a single sucrose gap and mechanical relaxation induced by Ca antagonists, isoproterenol and papaverine.
Topics: Action Potentials; Calcium; Calcium Channel Blockers; Humans; In Vitro Techniques; Isoproterenol; Ma | 1981 |
Cardiac glycosides and bronchomotor tone: effects of ouabain on tracheal smooth muscle contractility.
Topics: Airway Resistance; Animals; Bronchi; Cardiac Glycosides; Guinea Pigs; Histamine; In Vitro Techniques | 1981 |
Evidence against purinergic inhibitory nerves in the vagal pathway to the opossum lower esophageal sphincter.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Electric Stimulation; Electrophys | 1980 |
Effect of cholecystokinin and the octapeptide of cholecystokinin on the feline sphincter of Oddi and gallbladder. Mechanisms of action.
Topics: Ampulla of Vater; Animals; Cats; Cholecystokinin; Female; Gallbladder; Isoproterenol; Male; Muscle C | 1980 |
Signal transduction pathway involved in beta 3-adrenoceptor-mediated relaxation in guinea pig taenia caecum.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Butoxamine; Cecum; Culture Techniques; Cycl | 1995 |
Relaxant mechanisms of cyclic AMP-increasing agents in porcine coronary artery.
Topics: 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adr | 1994 |
The effects of toluene diisocyanate and of capsaicin on human bronchial smooth muscle in vitro.
Topics: Acetylcholine; Aged; Bronchi; Capsaicin; Female; Humans; In Vitro Techniques; Isoproterenol; Isotoni | 1994 |
Tachykinin NK3 receptor mediates NANC hyperpolarization and relaxation via nitric oxide release in the circular muscle of the guinea-pig colon.
Topics: Animals; Apamin; Arginine; Atropine; Colon; Dose-Response Relationship, Drug; Guanethidine; Guinea P | 1994 |
Modulation of nitric oxide-dependent relaxation of pig tracheal smooth muscle by inhibitors of guanylyl cyclase and calcium activated potassium channels.
Topics: Aminoquinolines; Animals; Calcium; Charybdotoxin; Electric Stimulation; Guanylate Cyclase; Isoproter | 1995 |
Inhibition of pituitary adenylate cyclase activating polypeptide induced relaxation of guinea-pig tracheal smooth muscle by charybdotoxin.
Topics: Animals; Charybdotoxin; Colforsin; Guinea Pigs; In Vitro Techniques; Isometric Contraction; Isoprote | 1995 |
Possible mechanisms of beta-adrenoceptor-mediated relaxation induced by noradrenaline in guinea pig taenia caecum.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Bupranolol; Cecum; Cyclic AMP; Guine | 1995 |
Pharmacological analysis of the interaction between purinoceptor agonists and antagonists in the guinea-pig taenia caecum.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cecum; Dipyridamole; Do | 1995 |
The involvement of ATP-sensitive potassium channels in beta-adrenoceptor-mediated vasorelaxation in the rat isolated mesenteric arterial bed.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; B | 1995 |
No evidence for a role of muscarinic M2 receptors in functional antagonism in bovine trachea.
Topics: Animals; Bronchoconstrictor Agents; Cattle; Dose-Response Relationship, Drug; Gallamine Triethiodide | 1995 |
Involvement of K+ channels in the relaxant responses to various agonists in estrogen primed rat uterus.
Topics: Animals; Benzopyrans; Calcium; Cromakalim; Dose-Response Relationship, Drug; Epinephrine; Estrogens; | 1995 |
Mechanism of protein kinase C potentiation of airway beta-adrenergic relaxation.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Analysis of Variance; Animals; Culture Techniques; Enzyme Ac | 1995 |
Evaluation of the relaxant effects of SCA40, a novel charybdotoxin-sensitive potassium channel opener, in guinea-pig isolated trachealis.
Topics: Animals; Carbachol; Charybdotoxin; Glyburide; Guinea Pigs; Imidazoles; In Vitro Techniques; Isoprote | 1993 |
Calcitonin gene-related peptide relaxes porcine coronary arteries via cyclic AMP-dependent mechanisms, but not activation of ATP-sensitive potassium channels.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Benzopyrans; Calcitonin Gene-Related P | 1993 |
Effect of an inhibitor of nitric oxide synthase on neural relaxation of human bronchi.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bronchi; Chymotrypsin; Dose-Response Relationship, Dr | 1993 |
Isoprenaline induces endothelium-independent relaxation and accumulation of cyclic nucleotides in the rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; In Vitro Tec | 1994 |
Potentiating effect of nicorandil, an antianginal agent, on relaxation induced by isoproterenol in isolated rat aorta: involvement of cyclic GMP-inhibitable cyclic AMP phosphodiesterase.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Angina Pectoris; Animals; Aorta; Cyclic AMP; Cyclic GMP; Drug S | 1995 |
5-HT-induced neurogenic relaxations of the guinea-pig proximal colon: investigation into the role of ATP and VIP in addition to nitric oxide.
Topics: Adenosine Triphosphate; Animals; Apamin; Colon; Female; Guinea Pigs; In Vitro Techniques; Isoprotere | 1995 |
The ontogeny of bladder function in the fetal calf.
Topics: Adenosine Triphosphate; Animals; Atropine; Bethanechol; Body Weight; Cattle; Electric Stimulation; F | 1995 |
Binding of A1 adenosine receptor ligand [3H]8-cyclopentyl-1,3-dipropylxanthine in coronary smooth muscle.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Binding, Competitive; Coronary Vessels; Cyclic AMP; GTP-B | 1995 |
Involvement of beta 3-adrenoceptor in the relaxation response in guinea pig taenia caecum.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Binding, Competitive; Butoxamine; Cecum; Dose-Respon | 1994 |
Endothelium-dependent contraction of canine coronary artery is enhanced after 24 hours of preservation with University of Wisconsin solution.
Topics: Acetylcholine; Adenosine; Adenosine Diphosphate; Allopurinol; Animals; Coronary Vessels; Dinoprost; | 1995 |
Screening of cattle urine samples for the presence of beta-agonists with a functional test: some preliminary results.
Topics: Adrenergic beta-Agonists; Animals; Cattle; Chromatography, Ion Exchange; Clenbuterol; Guinea Pigs; I | 1994 |
In vivo and in vitro influence of human recombinant hemoglobin on esophageal function.
Topics: Animals; Deglutition; Electric Stimulation; Esophagogastric Junction; Esophagus; Hemoglobins; Humans | 1995 |
Mechanisms of cyclic nucleotide-induced relaxation in canine tracheal smooth muscle.
Topics: Adenylyl Cyclases; Animals; Calcium Channels; Calcium-Transporting ATPases; Carbachol; Colforsin; Cy | 1995 |
Comparative studies on the ontogeny and autonomic responses of the fetal calf bladder at different stages of development: involvement of nitric oxide on field stimulated relaxation.
Topics: Adenosine Triphosphate; Animals; Arginine; Bethanechol; Bethanechol Compounds; Cattle; Electric Stim | 1994 |
Pulmonary vascular smooth muscle relaxation by cGMP- versus cAMP-mediated mechanisms.
Topics: Alprostadil; Amrinone; Analysis of Variance; Animals; Cyclic AMP; Cyclic GMP; Dose-Response Relation | 1994 |
Beta 1- and beta 2-adrenoceptor antagonist activities of ICI-215001, a putative beta 3-adrenoceptor agonist.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agon | 1994 |
The endothelium of the rat renal artery plays an obligatory role in A2 adenosine receptor-mediated relaxation induced by 5'-N-ethylcarboxamidoadenosine and N6-cyclopentyladenosine.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arginine; Endothelium, Vascular; Glyburide; I | 1994 |
Postnatal development of vascular beta-adrenoceptor-mediated responses and the increase in the adrenaline content of the adrenal gland have a parallel time course.
Topics: Adrenal Glands; Animals; Animals, Newborn; Colforsin; Dogs; Epinephrine; Female; Isoproterenol; Male | 1994 |
Inhibitory effect of sodium nitroprusside on the relaxing action of isoproterenol in isolated rat urinary bladder.
Topics: Animals; Cyclic GMP; Dobutamine; Electric Stimulation; In Vitro Techniques; Isoproterenol; Male; Met | 1994 |
[Effects of methylflavonolamine hydrochloride on tension and cAMP of isolated guinea pig trachea].
Topics: Aminophylline; Animals; Calcium Channel Blockers; Cyclic AMP; Dose-Response Relationship, Drug; Drug | 1994 |
[Effects of puerarin on cat vascular smooth muscle in vitro].
Topics: Animals; Cats; Dose-Response Relationship, Drug; Female; Femoral Vein; Isoflavones; Isoproterenol; M | 1994 |
Impaired endothelium-dependent relaxation after coronary reperfusion injury: evidence for G-protein dysfunction.
Topics: Acetylcholine; Adenosine Diphosphate; Aluminum Chloride; Aluminum Compounds; Animals; Calcimycin; Ca | 1994 |
The effects of phorbol 12,13-diacetate on responses of guinea-pig isolated trachea to methylxanthines, isoprenaline and ryanodine.
Topics: Animals; Caffeine; Calcium Chloride; Cold Temperature; Drug Interactions; Female; Guinea Pigs; Hista | 1994 |
Effects of muscarinic M2 and M3 receptor stimulation and antagonism on responses to isoprenaline of guinea-pig trachea in vitro.
Topics: Animals; Diamines; Dioxolanes; Guinea Pigs; Histamine; In Vitro Techniques; Isometric Contraction; I | 1994 |
Norepinephrine-induced relaxations in rat aorta mediated by endothelial beta adrenoceptors. Impairment by ageing and hypertension.
Topics: Aging; Animals; Aorta; Arginine; Endothelium, Vascular; Hypertension; In Vitro Techniques; Isoproter | 1994 |
Characterization of cyclic AMP accumulation in cultured human corpus cavernosum smooth muscle cells.
Topics: Alprostadil; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergis | 1994 |
Pilocarpine-induced relaxation of rat tail artery by a non-cholinergic mechanism and in the absence of an intact endothelium.
Topics: Acetylcholine; Action Potentials; Animals; Arteries; Autonomic Nervous System; Benzopyrans; Cromakal | 1994 |
Dissociation between bronchial hyperreactivity in vivo and reduced beta-adrenoceptor sensitivity in vitro in allergen-challenged guinea pigs.
Topics: Allergens; Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage F | 1994 |
Atypical beta-adrenoceptor- (beta 3-adrenoceptor) mediated relaxation of canine isolated bronchial smooth muscle.
Topics: Acetylcholine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Bronchi; C | 1993 |
Investigations into factors determining the duration of action of the beta 2-adrenoceptor agonist, salmeterol.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Electric Stimulation; Gui | 1993 |
Beta-adrenoceptor agonist mediated relaxation of rat isolated resistance arteries: a role for the endothelium and nitric oxide.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Arginine; Colforsin; Cyclic AMP; Dobutamine; Endotheli | 1993 |
Interaction of iberiotoxin with beta-adrenoceptor agonists and sodium nitroprusside on guinea pig trachea.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Drug Interactions; Guinea Pigs; In Vitro Techniques; I | 1993 |
Ca(++)-independent relaxation mediated by beta adrenoceptor in Ca(++)-independent contraction of uterine smooth muscle.
Topics: Adrenergic beta-Antagonists; Animals; Bucladesine; Calcium; Colforsin; Cyclic AMP; Egtazic Acid; Fem | 1993 |
The effectiveness of beta-adrenoceptor stimulation and the contribution of beta 1-adrenoceptors increase from the proximal to the distal part of the canine saphenous vein.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Colforsin; Dobutamine; Dog | 1993 |
Beta-adrenoceptor desensitization by/clenbuterol in rat uterus.
Topics: Adrenergic beta-Antagonists; Animals; Clenbuterol; Colforsin; Cyclic AMP; Estradiol; Female; In Vitr | 1993 |
The beta-adrenoceptors mediating relaxation of rat oesophageal muscularis mucosae are predominantly of the beta 3-, but also of the beta 2-subtype.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Esophagus; Ethanolamines; In Vitro T | 1993 |
Gamma-interferon modifies guinea pig airway functions in vitro.
Topics: Animals; Arginine; Carbachol; Cycloheximide; Guinea Pigs; In Vitro Techniques; Indomethacin; Interfe | 1994 |
Role of potassium channels in hypoxic relaxation of porcine bronchi in vitro.
Topics: Animals; Benzopyrans; Bronchi; Bronchodilator Agents; Carbachol; Cromakalim; Dose-Response Relations | 1994 |
The nicardipine-isoprenaline interaction in human and guinea-pig isolated airways.
Topics: Adenosine; Animals; Bronchi; Colforsin; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pig | 1994 |
Post-receptor pathway of the ATP-induced relaxation in smooth muscle of the mouse vas deferens.
Topics: Adenosine Triphosphate; Animals; Calcium; Cyclic AMP; Cytosol; In Vitro Techniques; Isoproterenol; M | 1993 |
Role of Ca(2+)-calmodulin dependent phospholamban phosphorylation on the relaxant effect of beta-adrenergic agonists.
Topics: Analysis of Variance; Animals; Calcium; Calcium-Binding Proteins; Calmodulin; Cyclic AMP; Densitomet | 1993 |
Influence of albumin on isoprenaline and propranolol effects on isolated rat uterus.
Topics: Animals; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Isoproterenol; Kinetics; Mus | 1993 |
CD-832, a new dihydropyridine derivative with both nitrate-like and Ca2+ channel antagonist vasodilator activities.
Topics: Animals; Aorta, Thoracic; Brain Chemistry; Calcium Channel Blockers; Cyclic AMP; Cyclic GMP; In Vitr | 1993 |
Muscarinic M2 receptors do not participate in the functional antagonism between methacholine and isoprenaline in guinea pig tracheal smooth muscle.
Topics: Animals; Gallamine Triethiodide; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Methach | 1993 |
Cardiovascular effects of SCA40, a novel potassium channel opener, in rats.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Cardiotonic Agents; Cardiovascular System; Dose-Response R | 1993 |
Involvement of the L-arginine: nitric oxide pathway in nonadrenergic noncholinergic relaxation of the cat gastric fundus.
Topics: Adrenergic Fibers; Animals; Arginine; Cats; Cholinergic Fibers; Electric Stimulation; Female; Gastri | 1993 |
Vaccine-derived Pasteurella haemolytica alter the responses of ovine pulmonary artery and vein to drugs acting on adenylate cyclase.
Topics: Animals; Bacterial Vaccines; Calcium; Endothelium, Vascular; In Vitro Techniques; Isometric Contract | 1993 |
Organ culture with proinflammatory cytokines reproduces impairment of the beta-adrenoceptor-mediated relaxation in tracheas of a guinea pig antigen model.
Topics: Animals; Carbachol; Cytokines; Female; Guinea Pigs; Interleukin-1; Interleukin-2; Isoproterenol; Mus | 1993 |
Activation of distinct cAMP- and cGMP-dependent pathways by relaxant agents in isolated gastric muscle cells.
Topics: Aminoquinolines; Animals; Arginine; Cell Separation; Colon; Cyclic AMP; Cyclic GMP; Digestive System | 1993 |
Effect of NG-monomethyl-L-arginine on the beta-adrenoceptor-mediated relaxation of rat mesenteric resistance arteries.
Topics: Animals; Arginine; In Vitro Techniques; Isoproterenol; Male; Mesenteric Arteries; Muscle Relaxation; | 1993 |
Inhibition of IP3 and IP3-dependent Ca2+ mobilization by cyclic nucleotides in isolated gastric muscle cells.
Topics: Animals; Calcium; Calcium Radioisotopes; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; G | 1993 |
Sensitization decreases relaxation in human isolated airways.
Topics: Asthma; Benzopyrans; Bronchi; Bucladesine; Carbachol; Colforsin; Cromakalim; Dose-Response Relations | 1993 |
Porcine diaphragmatic arteries. An in vitro comparative study.
Topics: Animals; Arginine Vasopressin; Arteries; Diaphragm; Endothelium, Vascular; In Vitro Techniques; Isop | 1993 |
Acetylcholine-induced endothelium-independent relaxations in monkey isolated superior and inferior caval veins.
Topics: Acetylcholine; Animals; Arginine; Aspirin; Calcimycin; Dinoprost; Endothelium, Vascular; Female; Gly | 1993 |
Comparison of the effects of selective inhibitors of phosphodiesterase types III and IV in airway smooth muscle with differing beta-adrenoceptor subtypes.
Topics: Albuterol; Animals; Bronchi; Cattle; Dose-Response Relationship, Drug; Guanidines; Guinea Pigs; In V | 1993 |
Comparative effects of activation of soluble and particulate guanylyl cyclase on cyclic GMP elevation and relaxation of bovine tracheal smooth muscle.
Topics: Animals; Atrial Natriuretic Factor; Cattle; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Histam | 1995 |
Indigo carmine inhibits endothelium-dependent and -independent vasodilation.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Calcimycin; Dose-Response Relationship, Drug; Endothelium, | 1996 |
Simultaneous measurement of intracellular calcium and tension in vascular smooth muscle: validation of the everted ring preparation.
Topics: Animals; Calcium; Coronary Vessels; Dinoprost; Endothelium, Vascular; Fluorometry; Fura-2; Isoproter | 1995 |
Functional evidence for the presence of beta 3-adrenoceptors in the guinea pig common bile duct and colon.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Bile Ducts; Colon; Female; Guinea P | 1995 |
Possible roles of nitric oxide and vasoactive intestinal polypeptide on relaxation induced by isoprenaline in isolated muscle strips of the mouse gastric fundus.
Topics: Adrenergic beta-Agonists; Animals; Arginine; Enzyme Inhibitors; Female; Gastric Fundus; In Vitro Tec | 1995 |
Effects of hydrogen peroxide on isolated trachealis muscle of horses.
Topics: Acetylcholine; Animals; Atropine; Dose-Response Relationship, Drug; Electric Stimulation; Horses; Hy | 1995 |
Relaxant actions of isoprenaline on guinea-pig isolated tracheal smooth muscle.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Female; Guin | 1995 |
Different atypical beta-adrenoceptors mediate isoprenaline-induced relaxation in vascular and non-vascular smooth muscles.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Ethanolamines; Female; In Vitro Tech | 1995 |
Mechanism of cytokine-induced modulation of beta-adrenoceptor responsiveness in airway smooth muscle.
Topics: Acetylcholine; Adenylate Cyclase Toxin; Animals; Cell Membrane; Colforsin; Cytokines; Diamines; Dino | 1996 |
beta-Adrenergic relaxation in mesenteric resistance arteries of spontaneously hypertensive and Wistar-Kyoto rats: the role of precontraction and intracellular Ca2+.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Calcium; Colforsin; Isoproterenol; Mal | 1996 |
Magnesium is essential in mechanisms of pulmonary vasomotor control.
Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Cyclic AMP; Cyclic GMP; Dose-Response Relationship | 1996 |
Effect of cyclosporin A on isolated rabbit bladder and urethral smooth muscle.
Topics: Acetylcholine; Animals; Clonidine; Cyclosporine; Dose-Response Relationship, Drug; Female; In Vitro | 1996 |
beta-Adrenoceptor activates endothelium-dependent release of nitric oxide in rat aorta.
Topics: Adrenergic beta-Agonists; Animals; Aorta, Thoracic; Arginine; Colforsin; Endothelium, Vascular; Fema | 1995 |
Functional evidence of atypical beta 3-adrenoceptors in the human colon using the beta 3-selective adrenoceptor antagonist, SR 59230A.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aged; Colon; Female; Humans; In Vitro Techniq | 1996 |
Characterization of muscarinic receptor and beta-adrenoceptor interactions in guinea-pig oesophageal muscularis mucosae.
Topics: Alkylation; Animals; Esophagus; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Male; Mu | 1995 |
Inhibition by zinc protoporphyrin-IX of vasoactive intestinal peptide-induced relaxations of guinea pig isolated trachea.
Topics: Animals; Dose-Response Relationship, Drug; Guinea Pigs; Immunohistochemistry; Isoproterenol; Male; M | 1996 |
Pharmacological study of atypical beta-adrenoceptors in rat esophageal smooth muscle.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Anta | 1996 |
Inhibition of cAMP-mediated relaxation of rabbit tracheal smooth muscle by neuropeptide Y.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Animals; Colforsin; Cyclic AMP; Isometric Con | 1996 |
Smooth muscle relaxant effects of tetrazepam on isolated guinea-pig and rat trachealis.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Calcium Channel Blockers; Carbacho | 1996 |
Effects of SCA40 on human bronchi and on guinea pig main bronchi in vitro. Comparison with cromakalim.
Topics: Acetylcholine; Animals; Benzopyrans; Bronchi; Bronchodilator Agents; Capsaicin; Charybdotoxin; Croma | 1996 |
Capsinolol: the first beta-adrenoceptor blocker with an associated calcitonin gene-related peptide releasing activity in the heart.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Anta | 1996 |
Mechanisms of impaired beta-adrenoceptor-induced airway relaxation by interleukin-1beta in vivo in the rat.
Topics: Animals; Autoradiography; Bronchi; Colforsin; Cyclic AMP; GTP-Binding Proteins; Interleukin-1; Isopr | 1996 |
Isolated, electrically-stimulated airway preparations--their use in determining beta-adrenoceptor agonist activity.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Animals; Bronchi; Cats; Drug Evaluati | 1996 |
Effects of cyclic GMP elevation on isoprenaline-induced increase in cyclic AMP and relaxation in rat aortic smooth muscle: role of phosphodiesterase 3.
Topics: Adrenergic beta-Agonists; Allopurinol; Animals; Aorta, Thoracic; Cells, Cultured; Colforsin; Cyclic | 1996 |
The inhibitory effects of iberiotoxin and 4-aminopyridine on the relaxation induced by beta 1- and beta 2-adrenoceptor activation in rat aortic rings.
Topics: 4-Aminopyridine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Analysis of Variance; Animal | 1996 |
The influence of hyperthyroidism on beta-adrenoceptor-mediated relaxation of isolated small mesenteric arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-Agonists; Adren | 1996 |
Beta 3-adrenoceptors mediating relaxation of the oesophageal tunica muscularis mucosae and distal colon in the rat: comparative pharmacology and their desensitization by BRL 37344.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Colon; Dose-Response Relationship, D | 1996 |
Influence of adrenodemedullation on beta 2- and beta 3-adrenoceptors mediating relaxation of oesophageal smooth muscle of spontaneously hypertensive rats.
Topics: Adrenal Medulla; Adrenalectomy; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Esop | 1996 |
Kinetic studies of desensitization and resensitization of the relaxation response to beta-2 adrenoceptor agonists in isolated guinea pig trachea.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Albuterol; Animals; Carbachol; Guinea | 1997 |
Heterogeneity of glyceryl trinitrate response in isolated bovine coronary arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bradykinin; Cattle; Cor | 1996 |
The effect of the protein phosphatases inhibitor cantharidin on beta-adrenoceptor-mediated vasorelaxation.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Cantharidin; Cattle; Cells, Cultured | 1997 |
Comparative studies on beta-adrenolytic potencies of some new phenoxyaminopropanol derivatives and celiprolol.
Topics: 1-Propanol; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Celi | 1997 |
Functional and molecular evidence for beta 1-, beta 2- and beta 3- adrenoceptors in human colon.
Topics: Adrenergic beta-Agonists; Carbachol; Colon; Humans; In Vitro Techniques; Isoproterenol; Muscle Contr | 1997 |
Chelerythrine, a protein kinase C inhibitor, interacts with cyclic nucleotide phosphodiesterases.
Topics: Adrenergic beta-Agonists; Alkaloids; Animals; Aorta; Benzophenanthridines; Cardiotonic Agents; Cattl | 1997 |
Inhibitory effects of ethanolic extracts of Boussingaultia gracilis on the spasmogen-induced contractions of the rat isolated gastric fundus.
Topics: Adrenergic beta-Agonists; Animals; Ethanol; Gastric Fundus; In Vitro Techniques; Isometric Contracti | 1997 |
Effects of putative K+ channel blockers on beta-adrenoceptor-mediated vasorelaxation of rat mesenteric artery.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Barium; Benzopyrans; Calcium; Charybdotox | 1997 |
Potentiation of the relaxing action of isoproterenol by forskolin in rabbit aortic rings: the involvement of beta 2-adrenoceptors.
Topics: Adenylyl Cyclases; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Animals; Aorta, Th | 1997 |
Ectopic expression of phospholamban in fast-twitch skeletal muscle alters sarcoplasmic reticulum Ca2+ transport and muscle relaxation.
Topics: Adrenergic beta-Agonists; Animals; Biological Transport; Blotting, Western; Calcium; Calcium-Binding | 1997 |
Phospholamban ablation enhances relaxation in the murine soleus.
Topics: Adenosine Triphosphatases; Animals; Calcium Channels; Calcium-Binding Proteins; Calcium-Transporting | 1997 |
Effect of Apafant on bronchial hyperresponsiveness and down-regulation of beta-adrenoceptors induced by endotoxin in guinea pigs.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Azepines; Binding Sites; Bronchial H | 1997 |
Beta(3)-adrenoceptors mediate smooth muscle relaxation in the rat lower oesophageal sphincter.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carbachol; Esophagogastric Junction; | 1997 |
Gallbladder relaxation in patients with pigment and cholesterol stones.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cholelithiasis; Cholesterol; Colforsin; Cyclic AMP; Cyclic G | 1997 |
Characterization of nerve-induced relaxation of gastrointestinal sphincteric smooth muscle in a South American opossum (Didelphis albiventris).
Topics: Animals; Atropine; Electric Stimulation; Esophagogastric Junction; Female; Guanethidine; In Vitro Te | 1997 |
Involvement of cyclic nucleotide-dependent protein kinases in cyclic AMP-mediated vasorelaxation.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Aorta; Calcium; Cardiotonic Agents; Cycli | 1997 |
Contraction and relaxation responses of femoral artery and aorta to norepinephrine in young rats.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agon | 1996 |
Inhibitory effects of Gs on desensitization of beta-adrenergic receptors in tracheal smooth muscle.
Topics: Adrenergic beta-Agonists; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protei | 1997 |
Lysophosphatidic acid enhances contractility of isolated airway smooth muscle.
Topics: Adrenergic beta-Agonists; Animals; Cats; Dose-Response Relationship, Drug; Endothelium; In Vitro Tec | 1997 |
Effects of SCA40 on bovine trachealis muscle and on cyclic nucleotide phosphodiesterases.
Topics: Animals; Bronchodilator Agents; Cattle; Cromakalim; Dose-Response Relationship, Drug; Electrophysiol | 1997 |
Changes in isoprenaline-induced endothelium-dependent and -independent relaxations of aorta in long-term STZ-diabetic rats: reversal effect of dietary vitamin E.
Topics: Animals; Aorta, Thoracic; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Isoproterenol | 1997 |
KATP channels contribute to beta- and adenosine receptor-mediated pulmonary vasorelaxation.
Topics: Acetylcholine; Adenosine; Adenylyl Cyclases; Animals; ATP-Binding Cassette Transporters; Colforsin; | 1997 |
Antenatal betamethasone therapy augments isoproterenol and prostaglandin E2-mediated relaxation of preterm ovine pulmonary veins.
Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Betamethasone; Cardiotonic Agents; Dinoprostone; Femal | 1997 |
G-protein-coupled receptor agonists augment adenylyl cyclase activity induced by forskolin in human corpus cavernosum smooth muscle cells.
Topics: Adenylyl Cyclases; Alprostadil; Carbachol; Cells, Cultured; Colforsin; Drug Interactions; Enzyme Act | 1997 |
Effect of Ca2+-channel blockers on isoprenaline-induced desensitization in rat trachea.
Topics: Animals; Calcium Channel Blockers; Carbachol; In Vitro Techniques; Isoproterenol; Male; Muscle Contr | 1997 |
Nonadrenergic-noncholinergic relaxations of isolated circular muscle from South American opossum esophagogastric junction: is nitric oxide the inhibitory mediator?
Topics: Adrenergic beta-Agonists; Animals; Autonomic Nervous System; Enzyme Inhibitors; Esophagogastric Junc | 1997 |
Effects of apafant on PAF-induced downregulation of beta-adrenoceptors in guinea pigs.
Topics: Adrenergic beta-Agonists; Animals; Azepines; Binding, Competitive; Bronchi; Down-Regulation; Guinea | 1997 |
Effect of different ozone concentrations on the neurogenic contraction and relaxation of guinea pig airways.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adrenergic Fibers; Animals; Atropine; Bronchi | 1997 |
Comparative study of effects of isoproterenol and vasoactive intestinal polypeptide on voltage-dependent Ca2+ and Ca(2+)-activated K+ currents in porcine tracheal smooth muscle cells.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Calcium Channels; Electrophysiology; Isoproterenol; Memb | 1998 |
Beta-adrenoceptor-mediated relaxation inhibited by tetrapentylammonium ions in rat mesenteric artery.
Topics: Adrenergic beta-Agonists; Animals; Fenoterol; Glyburide; In Vitro Techniques; Isoproterenol; Male; M | 1998 |
The effect of chronic treatment with trandolapril on cyclic AMP-and cyclic GMP-dependent relaxations in aortic segments of rats with chronic heart failure.
Topics: Acetylcholine; Adrenergic beta-Agonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihype | 1998 |
Effects of fenspiride on human bronchial cyclic nucleotide phosphodiesterase isoenzymes: functional and biochemical study.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Bronchi; Bronchodilator Agents; Dose-Response Relationship, Dru | 1998 |
Relaxant effects of NKH477, a new water-soluble forskolin derivative, on guinea-pig tracheal smooth muscle: the role of Ca2+-activated K+ channels.
Topics: Animals; Bronchodilator Agents; Calcium; Colforsin; Cyclic AMP; Guinea Pigs; Histamine; In Vitro Tec | 1998 |
The beta2- and beta3-adrenoceptor-mediated relaxation induced by isoprenaline and salbutamol in guinea pig taenia caecum.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Albuterol; Animals; Cecum; Dose-Respo | 1997 |
Developmental change in isoproterenol-mediated relaxation of pulmonary veins of fetal and newborn lambs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8-Bromo Cyclic Adenosine Monopho | 1998 |
Inhibitory effect of zinc protoporphyrin IX on lower esophageal sphincter smooth muscle relaxation by vasoactive intestinal polypeptide and other receptor agonists.
Topics: Animals; Bethanechol; Carbon Monoxide; Colforsin; Esophagogastric Junction; Heme Oxygenase (Decycliz | 1998 |
Mechanism of gallbladder relaxation in the cat: role of norepinephrine.
Topics: Animals; Cats; Electric Stimulation; Female; Gallbladder; In Vitro Techniques; Isoproterenol; Male; | 1998 |
Expression of beta3-adrenoceptors in rat detrusor smooth muscle.
Topics: Animals; Epinephrine; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; N | 1998 |
Bladder distension and activation of the efferent function of sensory fibres: similarities with the effect of capsaicin.
Topics: Adrenergic beta-Agonists; Animals; Capsaicin; Cyclooxygenase Inhibitors; Drug Interactions; Isoprote | 1998 |
Functional activity of antibodies at the bovine beta2-adrenoceptor.
Topics: Adrenergic beta-Agonists; Amino Acid Sequence; Animals; Antibodies; Binding, Competitive; Cattle; Fe | 1998 |
M2 muscarinic receptors inhibit forskolin- but not isoproterenol-mediated relaxation in bovine tracheal smooth muscle.
Topics: Animals; Cattle; Colforsin; Cyclic AMP; Diphenylacetic Acids; Histamine; In Vitro Techniques; Isopro | 1998 |
Beta3-adrenergic relaxation of bovine iris sphincter.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Bupranolol; Cattle; Colfo | 1998 |
Effect of age on in vitro magnesium modulation of vascular reactivity in the rat aorta.
Topics: Acetylcholine; Aging; Animals; Aorta; Calcium Chloride; Dose-Response Relationship, Drug; Endotheliu | 1998 |
Influence of gender on control of arterial tone in experimental hypertension.
Topics: Acetylcholine; Adenosine Diphosphate; Adrenergic beta-Agonists; Animals; Apamin; Blood Pressure; Cal | 1998 |
Atypical adrenoceptor-mediated relaxation of canine pulmonary artery through a cAMP-dependent pathway.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Cyclic AMP; Dioxoles; Dog | 1998 |
Possible beta 3-adrenoceptor-mediated relaxation of the human detrusor.
Topics: Adrenergic Antagonists; Adrenergic beta-Agonists; Adult; Aged; Bupranolol; Dobutamine; Dose-Response | 1998 |
Role of myosin heavy chain composition in kinetics of force development and relaxation in rat myocardium.
Topics: Adrenergic beta-Agonists; Animals; Calcium Signaling; Chelating Agents; Female; Half-Life; In Vitro | 1998 |
Relaxation of isolated human myometrial muscle by beta2-adrenergic receptors but not beta1-adrenergic receptors.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Female; Humans; Imidazoles; In Vitro Techniqu | 1998 |
Myorelaxant activity of 2-t-butyl-4-methoxyphenol (BHA) in guinea pig gastric fundus.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1998 |
Comparison of functional antagonism between isoproterenol and M2 muscarinic receptors in guinea pig ileum and trachea.
Topics: Animals; Colforsin; Diphenylacetic Acids; Guinea Pigs; Histamine; Ileum; Isoproterenol; Muscle Relax | 1999 |
Pertussis toxin increases isoproterenol induced relaxation in field-stimulated ileum.
Topics: Animals; Colforsin; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Histamine; | 1999 |
Functional and molecular biological evidence for a possible beta3-adrenoceptor in the human detrusor muscle.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonis | 1999 |
Differential regulation of inotropy and lusitropy in overexpressed Gsalpha myocytes through cAMP and Ca2+ channel pathways.
Topics: Animals; Calcium; Calcium Channels; Calcium-Binding Proteins; Cells, Cultured; Colforsin; Cyclic AMP | 1999 |
Functional characterization of beta-adrenoceptors mediating relaxation in sheep gallbladder.
Topics: Adrenergic beta-Agonists; Animals; Ethanolamines; Female; Gallbladder; In Vitro Techniques; Isoprote | 1999 |
Atypical beta-adrenoceptors mediating relaxation in the human colon: functional evidence for beta3-rather than beta4-adrenoceptors.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Colon; Ethano | 1999 |
Control of mesenteric arterial tone in vitro in humans and rats.
Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Calcimycin; Calcium; Cromakalim; Diclofenac; Endot | 1999 |
N-Type Ca(2+) channels trigger release of excitatory and inhibitory neurotransmitter from nerve endings in canine bronchi.
Topics: Acetylcholine; Agatoxins; Animals; Bronchi; Calcium Channel Blockers; Calcium Channels; Calcium Chan | 1999 |
Characterization of beta-adrenoceptor mediated smooth muscle relaxation and the detection of mRNA for beta1-, beta2- and beta3-adrenoceptors in rat ileum.
Topics: Adenylate Cyclase Toxin; Animals; Colforsin; Dioxoles; Dose-Response Relationship, Drug; Ethanolamin | 1999 |
[The effect of epithelium on inhibition of histamine-induced contraction of guinea-pig isolated trachea by potassium channel opener Rp 52891].
Topics: Aminophylline; Animals; Bronchodilator Agents; Epithelium; Female; Guinea Pigs; In Vitro Techniques; | 1997 |
Pharmacological characterization of beta-adrenoceptors mediating relaxation of the rat urinary bladder in vitro.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carbachol; In Vitro Techniques; Isop | 1999 |
Beta-adrenoceptor reserve in human lung: a comparison between airway smooth muscle and mast cells.
Topics: Analysis of Variance; Bronchodilator Agents; Female; Histamine Release; Humans; Isoproterenol; Lung; | 1999 |
The potentiating effect of genistein on the relaxation induced by isoproterenol in rat aortic rings.
Topics: Adrenergic beta-Agonists; Animals; Aorta; Benzoflavones; Bucladesine; Colforsin; Dose-Response Relat | 1999 |
Compliance, hysteresis, and collapsibility of human small airways.
Topics: Adult; Aged; Biomechanical Phenomena; Bronchi; Bronchoconstrictor Agents; Bronchodilator Agents; Com | 1999 |
Effects of propranolol and L-NAME on beta-adrenoceptor-mediated relaxation in rat carotid artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic beta-Agonists; Animal | 1999 |
Effect of pre-exposure to vasoconstrictors on isoprenaline-induced relaxation in rat aorta: involvement of inducible nitric oxide synthase.
Topics: Animals; Aorta; Blotting, Western; Cardiotonic Agents; In Vitro Techniques; Isoproterenol; Male; Mus | 1999 |
Alpha1-adrenoceptor antagonist effect of (+/-)-dobutamine in rat isolated gastric artery preparation.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-A | 1999 |
Influence of increase in osmotic pressure with sucrose on relaxation and cyclonucleotides levels in isolated rat aorta.
Topics: Adrenergic beta-Agonists; Animals; Aorta, Thoracic; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response | 1999 |
Nicotinic acetylcholine receptor blocking effect of guanethidine in the rat gastric fundus.
Topics: Animals; Electric Stimulation; Gastric Fundus; Guanethidine; Hexamethonium; In Vitro Techniques; Iso | 1999 |
Pharmacological analysis of atypical beta-adrenoceptors in the guinea pig gastric fundus using the beta(3)-adrenoceptor antagonist bupranolol.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Bupranolol; Butoxamine; Ca | 1999 |
beta-adrenergic relaxation of rabbit tracheal smooth muscle: a receptor deficit that improves with corticosteroid administration.
Topics: Acetylcholine; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents; | 2000 |
The relaxant activity of the methanolic extract of Acanthus montanus on intestinal smooth muscles.
Topics: Animals; Colon; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Intestines; Isopro | 1999 |
[Pharmacological analysis of atypical beta-adrenoceptors in the guinea pig gastrointestinal tissue systems].
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Bupranolol; Digestive System; Duoden | 1999 |
Milrinone, a phosphodiesterase III inhibitor, antagonizes the neuromuscular blocking effect of a non-depolarizing muscle relaxant in vitro.
Topics: Adrenergic beta-Agonists; Aminophylline; Animals; Colforsin; Diaphragm; Drug Interactions; Electric | 1999 |
Genistein potentiates the relaxation induced by beta1- and beta2-adrenoceptor activation in rat aortic rings.
Topics: Adrenergic beta-Agonists; Animals; Aorta; Dose-Response Relationship, Drug; Drug Synergism; Enzyme I | 2000 |
Beta 1-, beta 2- and atypical beta-adrenoceptor-mediated relaxation in rat isolated aorta.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Ani | 2000 |
Investigation of the interaction between nitric oxide and vasoactive intestinal polypeptide in the guinea-pig gastric fundus.
Topics: Adenine; Adrenergic beta-Agonists; Animals; Atrial Natriuretic Factor; Carbachol; Colforsin; Cyclic | 2000 |
Studies on muscarinic M2 receptors in smooth muscle.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cecum; Guinea Pigs; Histamine; In Vi | 1999 |
The effect of long-term streptozotocin-induced diabetes on contractile and relaxation responses of coronary arteries: selective attenuation of CGRP-induced relaxations.
Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Calcitonin Gene-Related Peptide; Coronary Vessels; | 2000 |
Effects of ovarian hormones on beta-adrenergic receptor-mediated relaxation in the female rabbit bladder.
Topics: Adrenergic beta-Agonists; Animals; Carbachol; Dobutamine; Estrogens; Female; Isoproterenol; Muscle R | 2000 |
Beta-adrenoceptor agonists in bronchial asthma: role of k+-channel opening in mediating their bronchodilator effects.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Anta | 1993 |
Relaxant effects of aflatoxins on isolated guinea pig trachea.
Topics: Aflatoxins; Animals; Bronchodilator Agents; Carbachol; Carcinogens; Cyclic AMP; Guinea Pigs; In Vitr | 2000 |
Comparative effect of amrinone, aminophylline and diltiazem on rat airway smooth muscle.
Topics: Acetylcholine; Adrenergic beta-Agonists; Aminophylline; Amrinone; Animals; Bronchodilator Agents; Ca | 2000 |
The P(2)-purinoceptor antagonist suramin is a competitive antagonist at vasoactive intestinal peptide receptors in the rat gastric fundus.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Binding, Competitive; Drug Interactions; | 2000 |
Functional assessment of beta adrenoceptor subtypes in human colonic circular and longitudinal (taenia coli) smooth muscle.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aged; Colon; Female; Humans; Imidazoles; Isop | 2000 |
Influence of heme oxygenase inhibitors on the basal tissue enzymatic activity and smooth muscle relaxation of internal anal sphincter.
Topics: Anal Canal; Animals; Deuteroporphyrins; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); In Vitro Te | 2000 |
Partial agonist activity of carteolol on atypical beta-adrenoceptors in the guinea pig duodenum.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Bupranolol; Carteolol; Dose-Response | 2000 |
Characterization of beta-adrenoceptor subtypes in the ferret urinary bladder in vitro and in vivo.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anesthesia; Animals; Blood Pressure; Dioxoles | 2000 |
Regional differences in signalling transduction pathways among smooth muscle cells from rabbit colon.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Calcium Signaling; Colon; Cyclic AMP; Cyclic GMP; Isopro | 2000 |
Relaxant effects of isoproterenol and selective beta3-adrenoceptor agonists on normal, low compliant and hyperreflexic human bladders.
Topics: Adrenergic beta-Agonists; Female; Humans; In Vitro Techniques; Isoproterenol; Male; Middle Aged; Mus | 2001 |
Relaxant effects of Hydrastis canadensis L. and its major alkaloids on guinea pig isolated trachea.
Topics: Alkaloids; Animals; Benzylisoquinolines; Berberine; Bronchodilator Agents; Complementary Therapies; | 2000 |
Pharmacological profile of T-1032, a novel specific phosphodiesterase type 5 inhibitor, in isolated rat aorta and rabbit corpus cavernosum.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aorta, Thoracic; Arginine; Cyclic Nucleotide Phosphodi | 2001 |
The influence of chronic inhibition of nitric oxide synthesis on contractile and relaxant properties of rat carotid and mesenteric arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-Agonists; Adren | 2000 |
Effect of protease-activated receptor (PAR)-1, -2 and -4-activating peptides, thrombin and trypsin in rat isolated airways.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bronchi; Bronchodilator Agents; Cyclooxygenase Inhibitors; Dos | 2000 |
beta(1)-Adrenoceptors compensate for beta(3)-adrenoceptors in ileum from beta(3)-adrenoceptor knock-out mice.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Dioxoles; Genotype; Ileum; In Vitro | 2001 |
Activity of N-(phenethyl)phenylethanolamines at beta(1) and beta(2) adrenoceptors: structural modifications can result in selectivity for either subtype.
Topics: Adrenergic beta-Agonists; Animals; Atrial Function, Right; Ethanolamines; Guinea Pigs; Isoproterenol | 2001 |
[Effect of taurine on the microvessel exchange function and adrenergic response of veins and arteries in the cat skeletal muscle].
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Arteries; Calcium; Capillary Permeabil | 2001 |
Functional properties of atypical beta-adrenoceptors on the guinea pig duodenum.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Alprenolol; Animals; Bupranolol; C | 2001 |
Further evidence that (+/-)-carteolol-induced relaxation is mediated by beta2-adrenoceptors but not by beta3-adrenoceptors in the guinea pig taenia caecum.
Topics: Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-3 Receptor Antagonists; Adrenergic beta-Anta | 2000 |
Vascular insulin/insulin-like growth factor-1 resistance in female obese Zucker rats.
Topics: Animals; Aorta; Cholera Toxin; Deoxyglucose; Drug Resistance; Endothelium, Vascular; Female; GTP-Bin | 2001 |
Relaxation of activated airway smooth muscle: relative potency of isoproterenol vs. tidal stretch.
Topics: Animals; Bronchial Spasm; Bronchodilator Agents; Cattle; Dose-Response Relationship, Drug; In Vitro | 2001 |
Serum-mediated relaxant response to toluene diisocyanate (TDI) in isolated guinea-pig bronchi.
Topics: Albumins; Analysis of Variance; Animals; Blood Proteins; Bronchi; Capsaicin; Culture Techniques; Dos | 2001 |
EP2 receptors mediate airway relaxation to substance P, ATP, and PGE2.
Topics: Acetylcholine; Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Dinoprostone; Isoprotereno | 2001 |
Chronic ethanol consumption impairs adrenoceptor- and purinoceptor-mediated relaxations of isolated rat detrusor smooth muscle.
Topics: Adenosine; Alcohol Drinking; Animals; Carbachol; Dose-Response Relationship, Drug; Ethanol; Isoprote | 2001 |
Protein kinase A-dependent and -independent effects of isoproterenol in rat isolated mesenteric artery: interactions with levcromakalim.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Algorithms; Animals; ATP-Binding Cassette Tra | 2001 |
Involvement of nitric oxide in non-adrenergic non-cholinergic relaxation and action of vasoactive intestinal polypeptide in circular muscle strips of the rat gastric fundus.
Topics: Adenylyl Cyclase Inhibitors; Animals; Electric Stimulation; Female; Gastric Fundus; Guanylate Cyclas | 2001 |
Association between IL-1beta/TNF-alpha-induced glucocorticoid-sensitive changes in multiple gene expression and altered responsiveness in airway smooth muscle.
Topics: Acetylcholine; Animals; Asthma; Dexamethasone; Gene Expression Profiling; Gene Expression Regulation | 2001 |
Beneficial effects of the Ca(2+) sensitizer levosimendan in human myocardium.
Topics: Calcium; Cardiotonic Agents; Cyclic AMP; Fluorescent Dyes; Fura-2; Heart; Heart Failure; Heart Trans | 2002 |
The role of beta(3)-adrenoceptors in mediating relaxation of porcine detrusor muscle.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Binding, Competitive; Dos | 2002 |
Studies on the expression and function of beta-3-adrenoceptors in the colon of rats with acetic acid-induced colitis.
Topics: Acetic Acid; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Colitis, Ulcerative; Co | 2002 |
Characterization of beta-adrenoceptor subtype in bladder smooth muscle in cynomolgus monkey.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anesthesia; Animals; Female; Isoproterenol; M | 2002 |
Estrogen levels influence beta-3-adrenoceptor-mediated relaxation of the female rat detrusor muscle.
Topics: Adrenergic beta-Agonists; Animals; Estrogens; Female; Isoproterenol; Muscle Relaxation; Ovariectomy; | 2002 |
Relaxation of heart muscle by catecholamines and by dibutyryl cyclic adenosine 3',5'-monophosphate. Similarity of beta-adrenoceptors mediating contractile and relaxant effects of catecholamines in kitten pipillary muscle.
Topics: Adrenergic beta-Antagonists; Animals; Anura; Bucladesine; Catecholamines; Cats; Drug Interactions; I | 1977 |
Specific enhancement of norepinephrine-induced contraction in rat veins after beta adrenergic antagonists.
Topics: Adrenergic beta-Antagonists; Animals; Drug Interactions; Electric Stimulation; In Vitro Techniques; | 1977 |
Analysis of hypotensive mechanisms of pindolol, a beta-adrenoceptor blocking drugs in rats.
Topics: Adrenergic beta-Antagonists; Anesthesia, Intravenous; Animals; Antihypertensive Agents; Blood Pressu | 1977 |
Beta-Adrenoceptor studies. 4. Influence of albumin on in vitro beta-adrenoceptor blocking and antiarrhythmic properties of propranolol, pindolol, practolol and metoprolol.
Topics: Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Guinea Pigs; Heart | 1977 |
Relaxation of depolarized guinea pig taenia caecum induced by some antispasmodics.
Topics: Animals; Benactyzine; Bucladesine; Calcium; Cecum; Cyclic AMP; Guinea Pigs; In Vitro Techniques; Iso | 1978 |
Cyclic AMP-independent relaxation of depolarized rat ileal smooth muscle by isoproterenol.
Topics: Adrenergic beta-Antagonists; Animals; Bucladesine; Calcium; Cyclic AMP; Female; Ileum; In Vitro Tech | 1978 |
Beta-adrenoceptor blockade by atenolol, metoprolol and propranolol in the anaesthetized cat.
Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Atenolol; Cats; Female; Heart Rate; Hemodynamics; | 1979 |
The beta-adrenoceptors responsible for a direct relaxation of the uncontracted nictitating membrane of the anaesthetized cat.
Topics: Albuterol; Animals; Blood Pressure; Cats; Dose-Response Relationship, Drug; Female; Heart Rate; Isop | 1977 |
Role of cyclic AMP in adrenergically induced tracheal smooth muscle relaxation.
Topics: Albuterol; Animals; Cattle; Cyclic AMP; Epinephrine; In Vitro Techniques; Isoproterenol; Muscle Cont | 1977 |
Effects of isoproterenol, theophylline and carbachol on cyclic nucleotide levels and relaxation of bovine tracheal smooth muscle.
Topics: Animals; Atropine; Carbachol; Cattle; Dose-Response Relationship, Drug; Isoproterenol; Muscle Relaxa | 1977 |
Relaxant effects of dopamine and isoprenaline on canine isolated coronary arteries--relationship to cyclic AMP production [proceedings].
Topics: Animals; Coronary Vessels; Cyclic AMP; Dogs; Dopamine; In Vitro Techniques; Isoproterenol; Muscle Co | 1978 |
Effects of isoprenaline on the time course of the cyclic AMP level in rat uterus.
Topics: Adenosine; Animals; Catechols; Corticosterone; Cyclic AMP; Dipyridamole; Female; Guanosine Triphosph | 1978 |
The beta-adrenergic responses in isolated splenic capsule area of several species of animals.
Topics: Animals; Cats; Dogs; Dose-Response Relationship, Drug; Epinephrine; Guinea Pigs; In Vitro Techniques | 1979 |
Effect of ACTH on the relaxation of guinea pig trachea with various bronchodilators.
Topics: Adrenocorticotropic Hormone; Airway Resistance; Albuterol; Aminophylline; Animals; Bronchodilator Ag | 1978 |
Cyclic AMP in the rat jugular vein: relationship to vascular relaxation.
Topics: Animals; Cyclic AMP; Isoproterenol; Jugular Veins; Male; Muscle Contraction; Muscle Relaxation; Musc | 1979 |
[The beta-adrenergic effects and cyclic AMP in the sphincter pupillae of the albino rabbit (author's transl)].
Topics: Animals; Cyclic AMP; In Vitro Techniques; Isoproterenol; Muscle Relaxation; Muscles; Propranolol; Pu | 1979 |
Prostacyclin increases cAMP in coronary arteries.
Topics: Adenosine; Animals; Arteries; Cattle; Coronary Vessels; Cyclic AMP; Dose-Response Relationship, Drug | 1979 |
Role of intracellular Ca2+ sequestration in beta-adrenergic relaxation of a smooth muscle.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Calcium; Cyclic AMP; Isoproterenol; Muscle | 1979 |
Mechanism of beta-adrenergic relaxation of smooth muscle.
Topics: Animals; Biological Transport, Active; Bufo marinus; Calcium; Cyclic AMP; Isoproterenol; Muscle Cont | 1979 |
Relaxant action of histamine on rabbit trachea: possible existence of third histamine receptor subtype.
Topics: Airway Resistance; Animals; Histamine; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscl | 1979 |
Specific antagonism by metoclopramide of dopamine-induced relaxation on isolated rabbit mesenteric arteries contracted with prostaglandin F2alpha.
Topics: Animals; Dopamine; Dopamine Antagonists; Female; In Vitro Techniques; Isoproterenol; Male; Mesenteri | 1979 |
Potassium-induced relaxations of the guinea-pig taenia coli.
Topics: Animals; Colon; Guanethidine; In Vitro Techniques; Isoproterenol; Male; Mice; Muscle Contraction; Mu | 1979 |
Distribution and characterization of the adrenoceptors in dog coronary arteries.
Topics: Animals; Coronary Vessels; Dogs; Epinephrine; Female; Isoproterenol; Male; Muscle Relaxation; Muscle | 1979 |
Antagonism by droperidol of dopamine-induced relaxation in isolated dog arteries.
Topics: Animals; Coronary Vessels; Dogs; Dopamine; Dopamine Antagonists; Droperidol; Drug Interactions; Fema | 1979 |
Pharmacological evaluation of the lung strip of neonatal swine.
Topics: Animals; Animals, Newborn; Carbachol; Female; Histamine; Indomethacin; Isoproterenol; Lung; Male; Mu | 1979 |
Effects of prostaglandin E1 on isolated dog renal artery.
Topics: Animals; Diltiazem; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Isoproteren | 1979 |
Isoprenaline relaxation in vascular smooth muscle of aged rats. Effect of flunarizine.
Topics: Aging; Animals; Blood Vessels; Drug Interactions; In Vitro Techniques; Isoproterenol; Muscle Contrac | 1977 |
Modification of the antispasmodic actions of isoproterenol and papaverine by removal of external Na in the isolated rat rectum.
Topics: Animals; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Sm | 1977 |
[Contraction-relaxation properties of experimental denervated and immobilized muscle: comparison with dystrophic muscle (author's transl)].
Topics: Action Potentials; Animals; Caffeine; Dantrolene; Humans; Immobilization; In Vitro Techniques; Isopr | 1978 |
A comparison of responses of guinea-pig isolated trachea to six prostaglandins.
Topics: Acetylcholine; Animals; Dose-Response Relationship, Drug; Guinea Pigs; Isoproterenol; Muscle Contrac | 1978 |
Influence of ageing on the isoprenaline relaxation of aortae from normal and hypertensive rats.
Topics: Aging; Animals; Aorta, Thoracic; Blood Pressure; Hypertension; In Vitro Techniques; Isoproterenol; M | 1978 |
Alternative mechanisms for the potentiation of the relaxation evoked by isoprenaline in aortae from young and aged rats.
Topics: Aging; Animals; Aorta, Thoracic; Blood Vessels; Cinnarizine; Drug Synergism; Isoproterenol; Muscle C | 1979 |
Activity and energy turnover in airway smooth muscle: influence of acetylcholine and isoprenaline.
Topics: Acetylcholine; Animals; Dogs; Drug Interactions; Energy Metabolism; Female; In Vitro Techniques; Iso | 1977 |
A possible role of decreased relaxation mediated by beta-adrenoceptors in bladder outlet obstruction by benign prostatic hyperplasia.
Topics: Adult; Aged; Aged, 80 and over; Colforsin; Dihydroalprenolol; Humans; In Vitro Techniques; Isometric | 1992 |
[Functional evaluation of possible cytokine receptors on airway smooth muscle: modification of airway smooth muscle responses by cytokines].
Topics: Animals; Carbachol; Guinea Pigs; In Vitro Techniques; Interferon-gamma; Interleukin-2; Isoproterenol | 1992 |
Neurally mediated relaxation of opossum internal anal sphincter: influence of superoxide anion generator and the scavenger.
Topics: Anal Canal; Animals; Atrial Natriuretic Factor; Hydroquinones; In Vitro Techniques; Isoproterenol; M | 1992 |
Changes in responsiveness of the aorta to vasorelaxant agents in genetically diabetic rats: a study in WBN/Kob rats.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Colforsin; Cromakalim; Diabetes Mellitus, Experimental; Endot | 1992 |
A comparison of beta-adrenergic receptors and in vitro relaxant responses to isoproterenol in asthmatic airway smooth muscle.
Topics: Asthma; Autoradiography; Binding, Competitive; Bronchi; Humans; Isoproterenol; Muscle Relaxation; Mu | 1992 |
Agonist-related differences in the relationship between cAMP content and protein kinase activity in canine trachealis.
Topics: Animals; Colforsin; Cyclic AMP; Dogs; Drug Interactions; Female; Isoproterenol; Male; Muscle Relaxat | 1992 |
[Membrane mechanisms of the relaxing effect of cyclic adenosine monophosphate in myometrial smooth muscle fibers].
Topics: Animals; Biological Transport; Calcium; Cations, Divalent; Cell Membrane; Colforsin; Cyclic AMP; Fem | 1992 |
Mechanism of the relaxant response of the rat duodenum to bradykinin.
Topics: Animals; Bradykinin; Calcium; Cells, Cultured; Cyclic AMP; Duodenum; Female; In Vitro Techniques; Is | 1992 |
BK1 and BK2 bradykinin receptors in the rat duodenum smooth muscle.
Topics: Animals; Apamin; Bradykinin; Cells, Cultured; Cyclic AMP; Duodenum; Female; Isoproterenol; Male; Mus | 1992 |
Novel signal transduction pathway mediating endothelium-dependent beta-adrenoceptor vasorelaxation in rat thoracic aorta.
Topics: Albuterol; Animals; Aorta, Thoracic; Arginine; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium, Vascu | 1992 |
Regional difference in functional roles of cAMP and cGMP in lower urinary tract smooth muscle contractility.
Topics: Animals; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Isop | 1992 |
Dissociation of magnitude of relaxation from cyclic AMP levels in rabbit urinary bladder smooth muscles.
Topics: Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; In Vitro Techniques; Isoproterenol | 1992 |
Mediation of contraction and relaxation by alpha- and beta-adrenoceptors in the ureterovesical junction of the sheep.
Topics: Adrenergic alpha-Agonists; Animals; Butoxamine; Isoproterenol; Male; Muscle Contraction; Muscle Rela | 1992 |
Mode of relaxing action of FK336, a new antianginal agent, in rabbit aorta.
Topics: Acetylcholine; Animals; Aorta; Calcium; Guanylate Cyclase; In Vitro Techniques; Inosine Monophosphat | 1992 |
Resistance of beta 2-adrenoceptor-mediated responses of lung strips to desensitization by long-term agonist exposure--comparison with atrial beta 1-adrenoceptor-mediated responses.
Topics: Adrenergic beta-Agonists; Animals; Carbachol; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniq | 1992 |
Relaxation of soman-induced contracture of airway smooth muscle in vitro.
Topics: Acetylcholine; Adrenergic beta-Agonists; Albuterol; Animals; Colforsin; Dogs; Dose-Response Relation | 1992 |
Atypical molecular pharmacology of a new long-acting beta 2-adrenoceptor agonist, TA 2005.
Topics: Adrenergic beta-Agonists; Amphetamines; Animals; Binding, Competitive; Bronchodilator Agents; Cattle | 1992 |
Atypical molecular pharmacology of a new long-acting beta 2-adrenoceptor agonist, TA 2005.
Topics: Adrenergic beta-Agonists; Amphetamines; Animals; Binding, Competitive; Bronchodilator Agents; Cattle | 1992 |
Atypical molecular pharmacology of a new long-acting beta 2-adrenoceptor agonist, TA 2005.
Topics: Adrenergic beta-Agonists; Amphetamines; Animals; Binding, Competitive; Bronchodilator Agents; Cattle | 1992 |
Atypical molecular pharmacology of a new long-acting beta 2-adrenoceptor agonist, TA 2005.
Topics: Adrenergic beta-Agonists; Amphetamines; Animals; Binding, Competitive; Bronchodilator Agents; Cattle | 1992 |
Inhibition of nitrovasodilator- and acetylcholine-induced relaxation and cyclic GMP accumulation by the cytochrome P-450 substrate, 7-ethoxyresorufin.
Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Aorta; Biotransformation; Cyclic GMP; Cytochrome P | 1992 |
Antagonists of nitric oxide synthesis inhibit nerve-mediated relaxations of longitudinal muscle in guinea pig ileum.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Guinea Pigs; Ileum; Isoproterenol; Male; Muscle Relax | 1992 |
Desensitization of beta-adrenoceptor- and prostaglandin E1 receptor-mediated human vascular smooth muscle relaxation.
Topics: Alprostadil; Dose-Response Relationship, Drug; Hand; Humans; Isoproterenol; Muscle Relaxation; Muscl | 1992 |
Role of potassium channels in bronchodilator responses in human airways.
Topics: Adolescent; Adult; Apamin; Benzopyrans; Bronchi; Bronchodilator Agents; Charybdotoxin; Child; Cromak | 1992 |
Effect of compounds from Mandevilla velutina on bradykinin-mediated contractile and relaxant responses of the isolated guinea pig trachea.
Topics: Animals; Bradykinin; Carbachol; Dinoprost; Epithelial Cells; Epithelium; Female; Guinea Pigs; Histam | 1992 |
Tracheal relaxation induced by potassium channel opening drugs: its antagonism by adrenergic neurone blocking agents.
Topics: Adrenergic Antagonists; Animals; Benzopyrans; Cromakalim; Dose-Response Relationship, Drug; Female; | 1992 |
Kinetics of relaxation responses to vasorelaxants in isolated rabbit aorta.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta, Thoracic; Dose-Response Relationship, | 1992 |
Crystalloid cardioplegia and hypothermia do not impair endothelium-dependent relaxation or damage vascular smooth muscle of epicardial coronary arteries.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Cardioplegic Solutions; Coronary Vessels; Dogs; Dose- | 1992 |
The relaxant effects of cromakalim (BRL 34915) on human isolated airway smooth muscle.
Topics: Acetylcholine; Benzopyrans; Bronchi; Bronchodilator Agents; Cromakalim; Drug Interactions; Histamine | 1992 |
Effect of Rb+ on cromakalim-induced relaxation and ion fluxes in guinea pig trachea.
Topics: Albuterol; Animals; Benzopyrans; Bronchodilator Agents; Cromakalim; Guinea Pigs; In Vitro Techniques | 1992 |
Nitric oxide is involved in 5-HT-induced relaxations of the guinea-pig colon ascendens in vitro.
Topics: Animals; Arginine; Colon; Female; Guinea Pigs; Hemoglobins; In Vitro Techniques; Isoproterenol; Male | 1992 |
Evidence that epithelium-dependent relaxation of vascular smooth muscle detected by co-axial bioassays is not attributable to hypoxia.
Topics: Animals; Aorta; Benzopyrans; Biological Assay; Biological Factors; Cromakalim; Epithelium; Glyburide | 1992 |
Effect of enalapril on the inotropic response to isoproterenol in renal hypertensive rats.
Topics: Animals; Body Weight; Cardiomegaly; Enalapril; Hypertension, Renovascular; Isoproterenol; Male; Musc | 1992 |
Effect of induced hypercholesterolemia in rabbits on functional responses of isolated large proximal and small distal coronary arteries.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Cholesterol, Dietary; Coconut Oil; Coronary Vessels; | 1992 |
M2 muscarinic receptors inhibit isoproterenol-induced relaxation of canine airway smooth muscle.
Topics: Animals; Dogs; Drug Interactions; Isoproterenol; Methacholine Chloride; Muscle Relaxation; Muscle, S | 1992 |
Effects of metabolic inhibitors on endothelium-dependent and endothelium-independent vasodilatation of rat and rabbit aorta.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Animals; Antimetabolites; Aorta, Thoracic; Bu | 1991 |
Hydrogen peroxide reduces beta-adrenoceptor function in the rat small intestine.
Topics: Animals; Bucladesine; Colforsin; Duodenum; Hydrogen Peroxide; Ileum; Intestine, Small; Isoproterenol | 1991 |
Evidence that nitric oxide participates in non-adrenergic inhibitory transmission to intestinal muscle in the guinea-pig.
Topics: Animals; Arginine; Autonomic Nervous System; Cecum; Colon; Electric Stimulation; Female; Guanethidin | 1991 |
Adrenaline-induced tracheal relaxation ex vivo is depressed following aerosol antigen challenge of sensitized guinea-pigs.
Topics: Aerosols; Anaphylaxis; Animals; Antigens; Epinephrine; Guinea Pigs; Heart; Heart Rate; In Vitro Tech | 1991 |
Inhibition of muscle cell relaxation by somatostatin: tissue-specific, cAMP-dependent, pertussis toxin-sensitive.
Topics: Adenosine Triphosphate; Adenylate Cyclase Toxin; Animals; Bucladesine; Cells, Cultured; Cyclic AMP; | 1991 |
Alpha- and beta-adrenoceptors in the sheep urinary bladder.
Topics: Adrenergic beta-Antagonists; Animals; Butoxamine; Isoproterenol; Male; Muscle Contraction; Muscle Re | 1991 |
Characterization of catecholamine-mediated relaxations in rat isolated gastric fundus: evidence for an atypical beta-adrenoceptor.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Catecholamines; Ethanolamines; Gastric | 1991 |
Relationship between cyclic guanosine monophosphate accumulation and relaxation of canine trachealis induced by nitrovasodilators.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Cyclic GMP; Dogs; Drug Synergism; Female; Guanylate Cy | 1991 |
Dicentrine, a natural vascular alpha 1-adrenoceptor antagonist, isolated from Lindera megaphylla.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Aporphines; Carbachol; Female; Guinea Pigs; | 1991 |
Salmeterol, a novel, long-acting beta 2-adrenoceptor agonist: characterization of pharmacological activity in vitro and in vivo.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Bronchodilator Agents; Dinoprost; Electric Stimulation | 1991 |
Tracheal relaxing effects and beta 2-selectivity of TA-2005, a newly developed bronchodilating agent, in isolated guinea pig tissues.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Amphetamines; Animals; Bronchodila | 1991 |
Tracheal relaxing effects and beta 2-selectivity of TA-2005, a newly developed bronchodilating agent, in isolated guinea pig tissues.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Amphetamines; Animals; Bronchodila | 1991 |
Tracheal relaxing effects and beta 2-selectivity of TA-2005, a newly developed bronchodilating agent, in isolated guinea pig tissues.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Amphetamines; Animals; Bronchodila | 1991 |
Tracheal relaxing effects and beta 2-selectivity of TA-2005, a newly developed bronchodilating agent, in isolated guinea pig tissues.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Amphetamines; Animals; Bronchodila | 1991 |
Beta-adrenoceptor profile of ractopamine HCl in isolated smooth and cardiac muscle tissues of rat and guinea-pig.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Female; Guinea Pigs; Heart; In Vitro Techniques; Isopr | 1991 |
Effects of pimobendan, a cardiotonic and vasodilating agent with phosphodiesterase inhibiting properties, on isolated arteries and veins of rats.
Topics: 1-Methyl-3-isobutylxanthine; Aminophylline; Animals; Arteries; Cardiotonic Agents; Colforsin; Drug I | 1990 |
Selective inhibition of relaxation of guinea-pig trachea by charybdotoxin, a potent Ca(++)-activated K+ channel inhibitor.
Topics: Aminophylline; Animals; Benzopyrans; Calcium; Carbachol; Charybdotoxin; Cromakalim; Dose-Response Re | 1990 |
Leukotriene receptor antagonism and augmentation of beta-receptor-mediated events by LY171883.
Topics: 1-Methyl-3-isobutylxanthine; Acetophenones; Adrenergic beta-Agonists; Animals; Bronchodilator Agents | 1990 |
Effects of cyclic AMP-affecting agents on contractile reactivity of isolated mesenteric and renal resistance arteries of the rat.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Arteries; Buclades | 1990 |
Deuterium oxide reduces agonist and depolarization-induced contraction of rat aortic rings.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1990 |
Relaxation response of isolated canine veins to agents that act on the adenylate cyclase-cyclic AMP system: further investigation.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Adrenergic alpha-Agonists; Animals; Colforsin; Cycli | 1990 |
Decreased beta-adrenoceptor-mediated vasodilation in aorta from aged rats: possible involvement of a stimulatory GTP-binding protein.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Aging; Animals; Aorta; Clenbuterol; Colforsin; Cycli | 1991 |
Effects of phosphodiesterase inhibitors on vasoactive intestinal peptide-induced relaxation of isolated guinea-pig trachea.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; Dinoprostone; Guinea Pigs; In Vitro Tec | 1991 |
Guinea-pig isolated trachealis: the effects of charybdotoxin on mechanical activity, membrane potential changes and the activity of plasmalemmal K(+)-channels.
Topics: Adrenergic beta-Agonists; Animals; Benzopyrans; Calcium; Cell Membrane; Charybdotoxin; Cromakalim; G | 1991 |
Inhibition of thrombin-induced endothelium-dependent relaxation after coronary ischemia in the dog: possible role of the coagulation cascade.
Topics: 4-Hydroxycoumarins; Acetylcholine; Amino Acid Chloromethyl Ketones; Animals; Blood Coagulation; Calc | 1991 |
Protein kinase C and phospholipase C in adenosine receptor-mediated relaxation in coronary artery.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Alkaloids; Animals; Coronary Vessel | 1991 |
In vitro responses of airway smooth muscle from horses with recurrent airway obstruction.
Topics: Acetylcholine; Airway Obstruction; Animals; Bronchi; Electric Stimulation; Horse Diseases; Horses; I | 1991 |
In vivo functional implications of isoproterenol-mediated relaxation of isolated human iris sphincter.
Topics: Aged; Aged, 80 and over; Carbachol; Ciliary Body; Humans; Iris; Isoproterenol; Muscle Relaxation; Pu | 1991 |
Ontogeny of responses of rabbit aorta to atrial natriuretic factor and isoproterenol.
Topics: Aging; Animals; Atrial Natriuretic Factor; Drug Interactions; Isoproterenol; Muscle Contraction; Mus | 1991 |
Role of cyclic nucleotide phosphodiesterase isozymes in intact canine trachealis.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine; Animals; Cyclic | 1991 |
Neutrophil-derived oxidants modify CCK-OP-stimulated guinea pig gallbladder contraction in vitro.
Topics: Animals; Calcitonin Gene-Related Peptide; Carbachol; Chloramines; Gallbladder; Glutathione; Guinea P | 1991 |
Angiotensin II generation in the rat vena cava: stimulation of local synthesis by beta-adrenoceptor activation.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Captopril; Female; Guinea Pigs; Heart Atria | 1991 |
Synergistic actions of nitrovasodilators and isoprenaline on rat aortic smooth muscle.
Topics: Adenylyl Cyclases; Animals; Aorta; Dose-Response Relationship, Drug; Drug Synergism; In Vitro Techni | 1991 |
Mechanical responses to catecholamines in the longitudinal muscle of guinea-pig gastric fundus.
Topics: Animals; Catecholamines; Dinoprostone; Epinephrine; Female; Gastric Fundus; Guinea Pigs; In Vitro Te | 1991 |
Isoproterenol activation of prostaglandin production in guinea-pig airway muscle preparations from immature and mature animals.
Topics: Aging; Animals; Bronchi; Dinoprost; Dinoprostone; Enzyme Activation; Guinea Pigs; Histamine; Isoprot | 1991 |
Stereoselectivity in beta-adrenomimetic and beta-adrenolytic actions of carteolol, a beta-adrenoceptor blocker with intrinsic sympathomimetic action in guinea-pig taenia caecum.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carteolol; Cecum; Guinea Pigs; In Vi | 1990 |
[Effect of a new selective alpha 2 adrenergic blocker, midaglizole, on isolated airway smooth muscle].
Topics: Adrenergic alpha-Antagonists; Animals; Bronchi; Dose-Response Relationship, Drug; Drug Synergism; Gu | 1990 |
The effects of (+/-)-, (+)- and (-)-celiprolol and bromoacetylalprenololmentane at the beta-adrenoceptors of rat isolated cardiovascular preparations.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Celiprolol; Electric Stimulation; Ethanolamines; H | 1990 |
A beta adrenoceptor with atypical characteristics is involved in the relaxation of the rat small intestine.
Topics: Adipose Tissue; Adrenergic beta-Antagonists; Animals; Ethanolamines; In Vitro Techniques; Intestine, | 1990 |
Effects of some autonomic drugs and neuropeptides on the mechanical activity of longitudinal and circular muscle strips isolated from the carp intestinal bulb (Cyprinus carpio).
Topics: Animals; Autonomic Agents; Carps; Epinephrine; Female; In Vitro Techniques; Intestines; Isoprotereno | 1990 |
The actions of some beta-receptor agonists and xanthines on isolated muscle strips from the human oesophago-gastric junction.
Topics: Adenosine; Adrenergic beta-Agonists; Adult; Aged; Dobutamine; Dose-Response Relationship, Drug; Esop | 1990 |
[Responses of muscle strips from the internal anal sphincter in Hirschsprung's disease to drugs and electrical field stimulation].
Topics: Anal Canal; Animals; Child, Preschool; Dogs; Electric Stimulation; Female; Hirschsprung Disease; Hum | 1990 |
Ryanodine reveals multiple contractile and relaxant mechanisms in vascular smooth muscle: simultaneous measurements of mechanical activity and of cytoplasmic free Ca2+ level with fura-2.
Topics: Animals; Caffeine; Calcium; Cytoplasm; Dinoprost; Egtazic Acid; Fura-2; Isoproterenol; Male; Muscle | 1990 |
Age-related changes in relaxant response of vascular smooth muscles to atrial natriuretic peptide.
Topics: Acetylcholine; Aging; Animals; Aorta; Atrial Natriuretic Factor; Body Weight; Dose-Response Relation | 1990 |
Identification of neurotransmitters by selective protection of postjunctional receptors.
Topics: Adenosine Triphosphate; Animals; Bucladesine; Colforsin; Electric Stimulation; Ethylmaleimide; Guine | 1990 |
Deficiency of beta-adrenoceptor-mediated relaxation in suncus trachea.
Topics: Animals; Colforsin; Dihydroalprenolol; Eulipotyphla; Guinea Pigs; In Vitro Techniques; Isoproterenol | 1990 |
Effects of a new cardiotonic agent 1,2-dihydro-6-methyl-2-oxo-5-[imidazo (1,2-a) pyridin-6-yl]-3-pyridine carbonitrile hydrochloride monohydrate (E-1020) on contractile force and cyclic AMP metabolism in canine ventricular muscle.
Topics: Amrinone; Animals; Bupranolol; Carbachol; Cardiotonic Agents; Cyclic AMP; Dogs; Female; Heart; Heart | 1990 |
Activation of cyclic AMP-dependent protein kinase during canine lower esophageal sphincter relaxation.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cardiotonic Agents; Dogs; Electric Stimulation; Enzyme | 1990 |
Chronic isoproterenol administration causes altered beta adrenoceptor-Gs-coupling in guinea pig lung.
Topics: Animals; Binding, Competitive; Dihydroalprenolol; Guanosine Triphosphate; Guinea Pigs; Isoproterenol | 1990 |
Beta 1-adrenoceptors mediate smooth muscle relaxation in mouse isolated trachea.
Topics: Animals; Atenolol; Betaxolol; Cocaine; Desoxycorticosterone; In Vitro Techniques; Isoproterenol; Mal | 1990 |
Age-related differences in cyclic AMP metabolism and their consequences on relaxation induced by isoproterenol and phosphodiesterase inhibitors in rat isolated aorta.
Topics: Adenylyl Cyclases; Aging; Animals; Aorta, Thoracic; Cyclic AMP; Isoproterenol; Male; Muscle Relaxati | 1990 |
Epithelium, contractile tone, and responses to relaxing agonists in canine bronchi.
Topics: Acetylcholine; Animals; Bronchi; Colforsin; Cyclic AMP; Cyclic GMP; Dogs; Epithelium; Female; In Vit | 1990 |
L-NG-nitro arginine inhibits non-adrenergic, non-cholinergic relaxations of guinea-pig isolated tracheal smooth muscle.
Topics: Acetylcholine; Animals; Arginine; Autonomic Nervous System; Chymotrypsin; Electric Stimulation; Guin | 1990 |
Enzymatic modulation of vasoactive intestinal peptide and nonadrenergic noncholinergic inhibitory responses in guinea pig tracheae.
Topics: Animals; Autonomic Nervous System; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation | 1990 |
Mode of inhibitory actions of acute and chronic chloroquine administration on the electrically stimulated mouse diaphragm in vitro.
Topics: Animals; Caffeine; Calcium; Chloroquine; Dantrolene; Diaphragm; Electric Stimulation; Female; In Vit | 1990 |
[Pharmacological experiments in aged rat urinary bladder. I. The responses to acetylcholine, norepinephrine and isoproterenol].
Topics: Acetylcholine; Age Factors; Animals; Female; In Vitro Techniques; Isoproterenol; Muscle Contraction; | 1990 |
Abnormalities in airway smooth muscle in fatal asthma.
Topics: Acetylcholine; Adult; Asthma; Cholinergic Fibers; Electric Stimulation; Female; Histamine; Humans; I | 1990 |
Effect of coenzyme Q10, a quinone derivative, on guinea pig lung and tracheal tissue.
Topics: Albuterol; Animals; Coenzymes; Dinoprost; Dinoprostone; Guinea Pigs; Histamine Release; In Vitro Tec | 1985 |
Pulmonary anti-anaphylactic activity of clenbuterol tested on actively and passively sensitized guinea-pigs.
Topics: Acetylcholine; Anaphylaxis; Animals; Bronchi; Clenbuterol; Ethanolamines; Female; Guinea Pigs; Hista | 1985 |
The relaxant action of nicorandil in guinea-pig isolated trachealis.
Topics: Aminophylline; Animals; Dose-Response Relationship, Drug; Female; Guinea Pigs; In Vitro Techniques; | 1986 |
Endothelium-independent linkage of parathyroid hormone receptors of rat vascular tissue with increased adenosine 3',5'-monophosphate and relaxation of vascular smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Aorta, Thoracic; Cells, Cultured; Colforsin | 1986 |
Age-related decrease in beta adrenergic receptor-mediated vascular smooth muscle relaxation.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Acetylcholine; Aging; B | 1986 |
Tetrodotoxin-resistant relaxation to transmural nerve stimulation in canine saphenous veins: a possible neural origin.
Topics: Animals; Ascorbic Acid; Catalase; Dogs; Electric Stimulation; In Vitro Techniques; Ion Channels; Iso | 1986 |
Parathyroid hormone-induced changes in cyclic nucleotide levels during relaxation of the rabbit [correction of rat] aorta.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aorta, Thoracic; Colforsin; Cyclic AMP; Cyclic GMP; In Vitro T | 1987 |
Beta-adrenergic relaxation of smooth muscle: differences between cells and tissues.
Topics: Adrenergic beta-Agonists; Animals; Bufo marinus; In Vitro Techniques; Ion Channels; Isoproterenol; M | 1987 |
ANP relaxes bovine tracheal smooth muscle and increases cGMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Atrial Natriuretic Factor; Carbachol; Cattle; Cyclic AMP; Cycl | 1989 |
Differential vasorelaxant effects of milrinone and amrinone on contractile responses of canine coronary, cerebral, and renal arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amrinone; Animals; Cerebral Arte | 1989 |
Role of phosphoinositide metabolism in functional antagonism of airway smooth muscle contraction by beta-adrenoceptor agonists.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Adrenergic beta-Agonists; Anim | 1989 |
Mast cell tryptase and chymase reverse airway smooth muscle relaxation induced by vasoactive intestinal peptide in the ferret.
Topics: Animals; Chymases; Dogs; Ferrets; Isoproterenol; Male; Mast Cells; Mast-Cell Sarcoma; Muscle Contrac | 1989 |
Comparison of relaxation induced by glyceryl trinitrate, isosorbide dinitrate, and sodium nitroprusside in bovine airways.
Topics: Animals; Carbachol; Cattle; Dose-Response Relationship, Drug; Ferricyanides; In Vitro Techniques; Is | 1989 |
Selective inhibition of endothelium-dependent relaxation by gold-containing compounds.
Topics: Animals; Auranofin; Calcimycin; Endothelium, Vascular; Gold; In Vitro Techniques; Isoproterenol; Mal | 1989 |
Effect of hydrogen peroxide on guinea-pig tracheal smooth muscle in vitro: role of cyclo-oxygenase and airway epithelium.
Topics: Animals; Catalase; Epithelium; Free Radicals; Guinea Pigs; Histamine; Hydrogen Peroxide; In Vitro Te | 1989 |
Relaxation of human peripheral airway smooth muscle in vitro does not correlate with severity of chronic airflow limitation in vivo.
Topics: Adult; Aged; Bronchi; Chronic Disease; Colforsin; Female; Forced Expiratory Volume; Humans; Isoprote | 1989 |
Role of cyclic AMP-dependent protein kinase in the diminished beta adrenergic responsiveness of vascular smooth muscle with increasing age.
Topics: Aging; Animals; Aorta; Colforsin; Cyclic AMP; In Vitro Techniques; Isoproterenol; Male; Mesenteric A | 1989 |
Involvement of endothelial cells in relaxation and contraction responses of the aorta to isoproterenol in naive and streptozotocin-induced diabetic rats.
Topics: Animals; Aorta; Colforsin; Diabetes Mellitus, Experimental; Drug Interactions; Endothelium, Vascular | 1989 |
Alpha 1-adrenoceptor function and autoradiographic distribution in human asthmatic lung.
Topics: Adult; Asthma; Autoradiography; Bronchi; Carbachol; Humans; In Vitro Techniques; Iodine Radioisotope | 1989 |
Contractile force and intracellular Ca2+ during relaxation of canine tracheal smooth muscle.
Topics: Acetylcholine; Aequorin; Animals; Calcium; Carbachol; Colforsin; Dogs; In Vitro Techniques; Indicato | 1989 |
Ethanol-induced bronchodilatation in TEA-treated canine tracheal smooth muscle is mediated by a beta-adrenoceptor-dependent mechanism.
Topics: Action Potentials; Animals; Cells, Cultured; Dogs; Ethanol; Female; Isoproterenol; Male; Muscle Rela | 1989 |
Analysis of the relaxant effects of AH 21-132 in guinea-pig isolated trachealis.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Acetylcholine; Animals; Female; Guinea Pigs; Histamine; | 1989 |
In vitro pharmacological properties of a series of isoprenaline derivatives.
Topics: Animals; Aorta, Thoracic; Binding, Competitive; Catecholamines; Dihydroalprenolol; Dobutamine; Dogs; | 1989 |
[Functional roles of cyclic AMP and cyclic GMP on rabbit urinary bladder and urethral smooth muscle contraction].
Topics: Animals; Cyclic AMP; Cyclic GMP; Female; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscl | 1989 |
Effects of diabetes and diuresis on contraction and relaxation mechanisms in rat urinary bladder.
Topics: Aminophylline; Animals; Bethanechol; Bethanechol Compounds; Choline O-Acetyltransferase; Diabetes Me | 1989 |
A comparison of the properties of prenalterol and corwin at beta 1- and beta 2-adrenoreceptors in vitro.
Topics: Adrenergic beta-Agonists; Animals; Cats; Dogs; Guinea Pigs; In Vitro Techniques; Isoproterenol; Musc | 1989 |
Desensitization of beta-adrenergic receptor-mediated vascular smooth muscle relaxation.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Catecholamines; Cyclic AMP; Epinephrine; In Vitro Techniques; | 1985 |
Adrenergic and VIP-ergic relaxatory mechanisms of the feline extrahepatic biliary tree.
Topics: Animals; Bile Ducts; Biomechanical Phenomena; Cats; Immunohistochemistry; Injections, Intra-Arterial | 1989 |
Contrast effects of isoproterenol and ouabain on left ventricular diastolic relaxation dysfunction in isolated, blood-perfused rabbit hearts.
Topics: Animals; Coronary Circulation; Diastole; In Vitro Techniques; Isoproterenol; Lactates; Male; Muscle | 1989 |
The effect of relaxants working through different transduction mechanisms on the tonic contraction produced in rat aorta by 4 beta-phorbol dibutyrate.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Colforsin; Cromakalim; In Vitro Techniques; Isoproterenol; Ma | 1989 |
Effects of experimental diabetes on the responsiveness of rat aorta.
Topics: Animals; Aorta, Thoracic; Body Water; Diabetes Mellitus, Experimental; In Vitro Techniques; Isoprote | 1989 |
Isoproterenol- and salbutamol-induced relaxation of acetylcholine- and histamine-induced contraction of equine trachealis muscle in vitro.
Topics: Acetylcholine; Albuterol; Analysis of Variance; Animals; Culture Techniques; Histamine; Horses; Isop | 1989 |
Epithelium- and mucosa-dependent relaxation and contraction of normal equine trachealis muscle in vitro.
Topics: Acetylcholine; Animals; Culture Techniques; Electric Stimulation; Epithelium; Horses; Isometric Cont | 1989 |
Catecholamines abolish vagal but not acetylcholine tone in the intact cat trachea.
Topics: Acetylcholine; Animals; Cats; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; | 1987 |
Role of platelet-activating factor (PAF) in the bronchopulmonary alterations and beta-adrenoceptor function induced by endotoxin.
Topics: Animals; Biological Assay; Endotoxins; Guinea Pigs; Histamine; Isoproterenol; Lung; Male; Muscle Con | 1988 |
Effect of Na-K adenosinetriphosphatase activity on relaxation of canine tracheal smooth muscle.
Topics: Animals; Calcium Channel Blockers; Colforsin; Dinoprostone; Dogs; In Vitro Techniques; Isoproterenol | 1988 |
Inhibition of the low km cyclic AMP phosphodiesterase in intact canine trachealis by SK&F 94836: mechanical and biochemical responses.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Bronchi; Cyclic GMP; Dogs; Dose-Response Relationship, | 1988 |
Effect of paf-acether on isoprenaline-induced relaxation in isolated tracheal segments of rats and guinea pigs.
Topics: Animals; Carbachol; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscl | 1988 |
Beta-adrenoceptor desensitization in guinea-pig isolated trachea.
Topics: Animals; Autoradiography; Carbachol; Female; Fenoterol; Guinea Pigs; Hydrocortisone; In Vitro Techni | 1988 |
Similarities between the relaxations induced by vasoactive intestinal peptide and by stimulation of the non-adrenergic non-cholinergic neurons in the rat stomach.
Topics: Animals; Apamin; Autonomic Nervous System; Chymotrypsin; Cyclic AMP; Electric Stimulation; In Vitro | 1988 |
The effect of parasympathetic decentralization on the feline urinary bladder.
Topics: Animals; Bethanechol; Bethanechol Compounds; Cats; Dose-Response Relationship, Drug; In Vitro Techni | 1985 |
Physiological approach of beta receptor coupling to adenylate cyclase in rat airways: ontogenical modification and functional antagonism.
Topics: Adenylyl Cyclases; Age Factors; Airway Resistance; Animals; Colforsin; Diterpenes; Dose-Response Rel | 1985 |
A beta-adrenoceptor blocking agent, befunolol as a partial agonist in isolated organs.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Guinea Pigs; Heart; Heart Rate; In V | 1985 |
[Anaphylaxis inhibits beta-adrenergic relaxation of guinea-pig tracheal smooth muscle].
Topics: Adrenergic beta-Agonists; Anaphylaxis; Animals; Guinea Pigs; In Vitro Techniques; Isoproterenol; Mal | 1985 |
Some actions of sodium nitroprusside and glyceryl trinitrate on guinea-pig isolated trachealis muscle.
Topics: Aminophylline; Animals; Ethacrynic Acid; Female; Ferricyanides; Guinea Pigs; In Vitro Techniques; Is | 1985 |
Animal model for the study of internal anal sphincter activity.
Topics: Adaptation, Physiological; Anal Canal; Animals; Female; Isoproterenol; Male; Models, Biological; Mus | 1985 |
Beta agonist-induced desensitization in pig bronchus.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Airway Resistance; Animals; Bronchi; Colforsi | 1986 |
Pharmacological studies on the intrinsic sympathomimetic activity of the beta-adrenoceptor antagonist mepindolol.
Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Heart; Hemodynamics; In Vitro Techniques; Isoprote | 1986 |
Pharmacological evaluation of the beta-adrenoceptor agonist and thromboxane antagonist properties of N-substituted trimetoquinol analogues.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic beta-Agonists; Animal | 1987 |
The guinea-pig trachea O-methylating system is more effective in modulating beta 2- than beta 1-adrenoceptor-mediated responses to isoprenaline.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Guinea Pigs; In Vitro Techniques; Isoproterenol; Met | 1988 |
Vasoactive intestinal polypeptide as possible mediator of relaxation in the rat gastric fundus.
Topics: Animals; Electric Stimulation; Female; Gastric Fundus; In Vitro Techniques; Isoproterenol; Male; Mus | 1988 |
Some pharmacological properties of the circular smooth muscle layer of the rat vas deferens.
Topics: Animals; Binding, Competitive; Cocaine; Corticosterone; In Vitro Techniques; Isoproterenol; Male; Me | 1988 |
Comparison of atriopeptins II and III, VIP and beta 2-adrenoceptor-evoked relaxations of the two layers of smooth muscle in the rat portal vein.
Topics: Animals; Atrial Natriuretic Factor; Atropine; Female; Isoproterenol; Methoxamine; Methylene Blue; Mu | 1987 |
Effect of vasoactive intestinal polypeptide (VIP) on cyclic AMP level and relaxation in rat isolated aorta.
Topics: Animals; Aorta; Cyclic AMP; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle Relaxatio | 1985 |
Inhibitory effect of methacholine on drug-induced relaxation, cyclic AMP accumulation, and cyclic AMP-dependent protein kinase activation in canine tracheal smooth muscle.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Cyclic AMP; Dinoprostone; Diterpenes; Do | 1985 |
Steric aspects of agonism and antagonism at beta-adrenoceptors: experiments with the enantiomers of clenbuterol.
Topics: Animals; Carbachol; Clenbuterol; Ethanolamines; Guinea Pigs; Heart Ventricles; In Vitro Techniques; | 1985 |
Changes in cyclic AMP and cyclic GMP levels in the contraction-relaxation cycle of isolated smooth muscle cells from guinea-pig taenia caeci.
Topics: Animals; Caffeine; Colon; Cyclic AMP; Cyclic GMP; Guinea Pigs; In Vitro Techniques; Isoproterenol; M | 1985 |
Calcitonin gene-related peptide stimulates cyclic AMP formation in rat aortic smooth muscle cells.
Topics: Animals; Atrial Natriuretic Factor; Calcimycin; Calcitonin Gene-Related Peptide; Cells, Cultured; Cy | 1985 |
Some effects of orthovanadate on smooth muscle cells of guinea-pig taenia caeci.
Topics: Animals; Carbachol; Cecum; Electrophysiology; Guinea Pigs; In Vitro Techniques; Isoproterenol; Muscl | 1985 |
[Effect of isoprenaline and the barium ion on the relaxation of the smooth muscle of the guinea pig trachea].
Topics: Animals; Barium; Colforsin; Cyclic AMP; Guinea Pigs; In Vitro Techniques; Ions; Isoproterenol; Muscl | 1985 |
The influence of Bordetella pertussis and its constituents on the beta-adrenergic receptor in the guinea pig respiratory system.
Topics: Animals; Carbachol; Endotoxins; Epinephrine; Guinea Pigs; Isoproterenol; Lung; Male; Muscle Contract | 1986 |
Apamin distinguishes two types of relaxation mediated by enteric nerves in the guinea-pig gastrointestinal tract.
Topics: Adenosine Diphosphate; Animals; Apamin; Bee Venoms; Colon; Digestive System; Dogs; Female; Ileum; In | 1986 |
Responses of isolated dog blood vessels to glucagon.
Topics: Animals; Bucladesine; Coronary Vessels; Cyclic AMP; Dogs; Endothelium; Female; Glucagon; In Vitro Te | 1986 |
Effects of prostaglandin E1, isoproterenol and forskolin on cyclic AMP levels and tension in rabbit aortic rings.
Topics: Alprostadil; Animals; Colforsin; Cyclic AMP; In Vitro Techniques; Isoproterenol; Muscle Relaxation; | 1986 |
Experimental model of anaphylaxis-induced beta-adrenergic blockade in the airways.
Topics: Alprostadil; Aminophylline; Anaphylaxis; Animals; Colforsin; Guinea Pigs; In Vitro Techniques; Isopr | 1986 |
Enhanced relaxation response of canine coronary artery to isoproterenol and salbutamol after removal of endothelial cells.
Topics: Acetylcholine; Albuterol; Animals; Coronary Vessels; Dogs; Endothelium; In Vitro Techniques; Isoprot | 1986 |
Lower esophageal sphincter relaxation is associated with increased cyclic nucleotide content.
Topics: Animals; Atrial Natriuretic Factor; Cyclic AMP; Cyclic GMP; Dopamine; Electric Stimulation; Esophagu | 1986 |
Different types of relationship between beta-adrenergic relaxation and activation of cyclic AMP-dependent protein kinase in canine saphenous and portal veins.
Topics: Animals; Bucladesine; Colforsin; Cyclic AMP; Dogs; In Vitro Techniques; Isoproterenol; Muscle Relaxa | 1986 |
Decline in beta adrenergic receptor-mediated vascular relaxation with aging in man.
Topics: Adult; Aged; Aging; Cyclic AMP; Humans; Isoproterenol; Male; Middle Aged; Muscle Relaxation; Muscle, | 1986 |
The time course of changes in force and cyclic AMP levels produced by isoproterenol and forskolin in isolated rabbit detrusor muscle.
Topics: Animals; Colforsin; Cyclic AMP; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle Relax | 1987 |
Effects of isoproterenol on active force and Ca2+ X calmodulin-sensitive phosphodiesterase activity in porcine coronary artery.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Coronary Vessels; In Vitro Techniques; Isoproterenol; | 1987 |
Dual effects of Haemophilus influenzae on guinea pig tracheal beta-adrenergic receptor function: involvement of oxygen-centered radicals from pulmonary macrophages.
Topics: Animals; Free Radicals; Guinea Pigs; Haemophilus influenzae; Hydroxides; Hydroxyl Radical; Isoproter | 1987 |
Comparison of maximal bronchoconstriction in vivo and airway smooth muscle responses in vitro in nonasthmatic humans.
Topics: Adult; Aged; Asthma; Bronchi; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Humans; | 1988 |
Influence of endothelium on drug-induced relaxation of the rabbit aorta.
Topics: Animals; Aorta, Thoracic; Endothelium; Female; In Vitro Techniques; Isometric Contraction; Isoproter | 1986 |
The role of hyperpolarization in the relaxation of smooth muscle of monkey coronary artery.
Topics: Action Potentials; Animals; Coronary Vessels; Endothelium; Female; Haplorhini; In Vitro Techniques; | 1986 |
Comparison of the responses to drugs acting on adrenoreceptors and muscarinic receptors in human isolated corpus cavernosum and cavernous artery.
Topics: Acetylcholine; Aged; Carbachol; Clonidine; Electric Stimulation; Ethanolamines; Humans; In Vitro Tec | 1985 |
Relaxant actions of viprostol and prostaglandin E2 on tracheal muscle and their effects on calcium influx.
Topics: Animals; Calcium; Calcium Chloride; Carbachol; Dinoprostone; Guinea Pigs; Isoproterenol; Macaca fasc | 1988 |
Micturition in the unanesthetized rat: spinal vs. peripheral pharmacology of the adrenergic system.
Topics: Animals; Isoproterenol; Methoxamine; Muscle Contraction; Muscle Relaxation; Norepinephrine; Peripher | 1988 |
Antagonism of relaxation to isoproterenol caused by agonist interactions.
Topics: Acetylcholine; Animals; Dogs; Drug Interactions; Female; Histamine; In Vitro Techniques; Isoproteren | 1988 |
Changes in sensitivity of the rat stomach fundus to various drugs in streptozotocin-induced diabetic rats.
Topics: Acetylcholine; Animals; Diabetes Mellitus, Experimental; In Vitro Techniques; Isoproterenol; Male; M | 1988 |
Age-dependent changes in the response of isolated beagle coronary arteries to transmural electrical stimulation and catecholamines.
Topics: Acetylcholine; Aging; Animals; Catecholamines; Coronary Circulation; Coronary Vessels; Dinoprost; Do | 1986 |
Differential effects of methacholine and leukotriene D4 on cyclic nucleotide content and isoproterenol-induced relaxation in the opossum trachea.
Topics: Airway Resistance; Animals; Female; In Vitro Techniques; Isoproterenol; Male; Methacholine Chloride; | 1986 |
Regional differences in relaxation of electric field-stimulated canine airway smooth muscle by verapamil, isoproterenol and prostaglandin E2.
Topics: Animals; Dinoprostone; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Female; Isoprot | 1986 |
Potentiation of isoproterenol-induced relaxation of isolated trachea by aminophylline: modulation by desensitization.
Topics: Aminophylline; Animals; Drug Synergism; Drug Tolerance; Female; Guinea Pigs; Isoproterenol; Male; Mu | 1987 |
Comparison of VIP and beta 2-adrenoceptor-induced relaxations in the circular and longitudinal smooth muscle layers of the rat portal vein.
Topics: Albuterol; Animals; Apamin; Female; Isoproterenol; Methoxamine; Muscle Contraction; Muscle Relaxatio | 1987 |
Pharmacological characterization of the effects of verapamil and nifedipine on isolated guinea-pig lung parenchymal strip.
Topics: Acetylcholine; Animals; Calcium; Calcium Chloride; Guinea Pigs; Histamine; In Vitro Techniques; Isop | 1986 |
Inhibitory effects of selected purine derivatives on guinea pig pulmonary tissues.
Topics: Adenine Nucleotides; Adenosine; Animals; Cricetinae; Dose-Response Relationship, Drug; Female; Hista | 1986 |
Cerebral vascular responsiveness in deoxycorticosterone acetate-salt hypertensive rats.
Topics: Animals; Basilar Artery; Blood Pressure; Calcium; Cerebrovascular Circulation; Desoxycorticosterone; | 1987 |
Noradrenergic and non-noradrenergic relaxation at basal and high tone levels in the guinea-pig tracheal smooth muscle.
Topics: Animals; Carbachol; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Isometric Contra | 1986 |
Facilitation of isoproterenol induced airway smooth muscle relaxation by nifedipine.
Topics: Animals; Drug Synergism; Guinea Pigs; In Vitro Techniques; Isoproterenol; Kinetics; Male; Muscle Con | 1985 |
Phentolamine and rat aortic smooth muscle responsiveness to potassium chloride, isoproterenol and norepinephrine.
Topics: Animals; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nore | 1985 |
Streptozocin-induced diabetes affects rat urinary bladder response to autonomic agents.
Topics: Acetylcholine; Animals; Autonomic Agents; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Do | 1985 |
Effects of two venotropic drugs on inactivation and O-methylation of catecholamines in an isolated canine vein.
Topics: Animals; Anticoagulants; Catechol O-Methyltransferase Inhibitors; Catecholamines; Dogs; Electric Sti | 1985 |