Page last updated: 2024-10-29

isoproterenol and Malignant Melanoma

isoproterenol has been researched along with Malignant Melanoma in 6 studies

Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.

Research Excerpts

ExcerptRelevanceReference
" Using pharmacological approaches, evaluation of Ki-67 expression by flow cytometry and luciferase-based cAMP assay, we found that treatment with isoproterenol, a β-AR agonist, increased cAMP levels in B16F10 melanoma cells without affecting cell proliferation."4.12Crosstalk between β2- and α2-Adrenergic Receptors in the Regulation of B16F10 Melanoma Cell Proliferation. ( Ambrosio, C; Ascione, B; Grò, MC; Maccari, S; Marano, G; Matarrese, P; Molinari, P; Stati, T; Vezzi, V; Vona, R, 2022)
"Different pharmacologic drugs (isadrin, obsidan, phentolamine) changing adrenergic processes are shown to have different effect on the growth and development of lung metastases."3.67[Changes in the metastasis of experimental tumors and in the antimetastatic effect of cytostatics in their pharmacological action on adrenergic processes]. ( Balitskiĭ, KP; Riabukha, VN; Smelkova, MI; Veksler, IG, 1984)
"3 mM) moderately increased the tyrosinase activity of cultured human melanoma cells, while another beta-adrenoceptor agonist, terbutaline (1-3 mM) and a catechol compound, dopac (0."3.67Stimulation of tyrosinase by dihydroxy phenyl derivatives. ( Karg, E; Rorsman, H; Rosengren, E, 1989)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19904 (66.67)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Matarrese, P1
Maccari, S1
Ascione, B1
Vona, R1
Vezzi, V1
Stati, T1
Grò, MC1
Marano, G1
Ambrosio, C1
Molinari, P1
Blagoeva, PM1
Balansky, RM1
Veksler, IG1
Riabukha, VN1
Smelkova, MI1
Balitskiĭ, KP1
Nilius, B1
Böhm, T1
Wohlrab, W1
Karg, E2
Johansson, LH1
Hindemith-Augustsson, A1
Rosengren, E2
Rorsman, H2

Other Studies

6 other studies available for isoproterenol and Malignant Melanoma

ArticleYear
Crosstalk between β2- and α2-Adrenergic Receptors in the Regulation of B16F10 Melanoma Cell Proliferation.
    International journal of molecular sciences, 2022, Apr-22, Volume: 23, Issue:9

    Topics: Adrenergic beta-Agonists; Cell Line, Tumor; Cell Proliferation; Humans; Isoproterenol; Melanoma; Pro

2022
Effect of theophyllin and isoproterenol on cAMP level in melanotic and amelanotic hamster melanomas.
    Tumori, 1983, Oct-31, Volume: 69, Issue:5

    Topics: Animals; Cell Differentiation; Cricetinae; Cyclic AMP; Isoproterenol; Male; Melanoma; Mesocricetus;

1983
[Changes in the metastasis of experimental tumors and in the antimetastatic effect of cytostatics in their pharmacological action on adrenergic processes].
    Eksperimental'naia onkologiia, 1984, Volume: 6, Issue:6

    Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Drug Evaluation, Preclinical; Drug Therapy, Combin

1984
Properties of a potassium-selective ion channel in human melanoma cells.
    Pflugers Archiv : European journal of physiology, 1990, Volume: 417, Issue:3

    Topics: alpha-MSH; Cyclic AMP; Electric Conductivity; Electrophysiology; Humans; Isoproterenol; Melanoma; Po

1990
Adenylate cyclase activity in homogenates of human melanoma cells. Effect of alpha-MSH and isoprenaline.
    Acta dermato-venereologica, 1989, Volume: 69, Issue:4

    Topics: Adenylyl Cyclases; Cells, Cultured; Cyclic AMP; Guanosine Triphosphate; Humans; Isoproterenol; Melan

1989
Stimulation of tyrosinase by dihydroxy phenyl derivatives.
    Acta dermato-venereologica, 1989, Volume: 69, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Catechol Oxidase; Cell Line; Enzyme Activation; Humans; Isoprotereno

1989