isoproterenol has been researched along with Left Ventricular Hypertrophy in 108 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A previous study by our group demonstrated a protective role of the neuropeptide secretoneurin (SN) in DL‑isoproterenol hydrochloride (ISO)‑induced cardiac hypertrophy in mice." | 7.96 | iTRAQ‑based quantitative proteomics analysis of the potential application of secretoneurin gene therapy for cardiac hypertrophy induced by DL‑isoproterenol hydrochloride in mice. ( Chen, H; Jiang, W; Liu, X; Wu, M; Yu, C; Zhang, J, 2020) |
| " This study evaluated whether LCZ696 affects left ventricular hypertrophy, fibrosis, and hemodynamics in isoproterenol (ISO)-treated rats compared with valsartan alone." | 7.91 | Effect of LCZ696, a dual angiotensin receptor neprilysin inhibitor, on isoproterenol-induced cardiac hypertrophy, fibrosis, and hemodynamic change in rats. ( Akagi, S; Ito, H; Kondo, M; Miura, D; Miyoshi, T; Nakamura, K; Ohno, Y; Saito, Y; Yoshida, M, 2019) |
| " Furthermore, the effects of 2-ME on blood pressure and cardiovascular remodeling in the constricted aorta (CA) rat model and on isoproterenol-induced (ISO) cardiac hypertrophy and fibrosis were examined." | 7.91 | 2-Methoxyestradiol Attenuates Angiotensin II-Induced Hypertension, Cardiovascular Remodeling, and Renal Injury. ( Bastacky, SI; Jackson, EK; Salah, E; Tofovic, SP, 2019) |
| "Low-dose rosuvastatin exerted cardioprotective effects on isoproterenol-induced heart failure in rats by modulating DDAH-ADMA-NO pathway, and it may present the new therapeutic value in ameliorating chronic heart failure." | 7.85 | Protective effects of low-dose rosuvastatin on isoproterenol-induced chronic heart failure in rats by regulation of DDAH-ADMA-NO pathway. ( Ma, P; Wang, Y; Xiong, A; Xu, Q; Xu, Y; Zhou, R, 2017) |
| "We aimed to understand the genetic control of cardiac remodeling using an isoproterenol-induced heart failure model in mice, which allowed control of confounding factors in an experimental setting." | 7.83 | Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model. ( Avetisyan, R; Gong, KW; Lusis, AJ; Rau, C; Ren, S; Romay, MC; Stolin, G; Wang, JJ; Wang, Y, 2016) |
| "Gene expression of heparanase, matrix metalloproteinases (MMP)-2 and MMP-9 were examined in ventricles after chronic treatment with isoproterenol (ISO) induced cardiac hypertrophy in rats." | 7.73 | Induction of heparanase gene expression in ventricular myocardium of rats with isoproterenol-induced cardiac hypertrophy. ( Hara, Y; Hashizume, K; Ito, R; Kizaki, K; Mutoh, K; Okada, M; Yoshioka, K, 2005) |
| "This study investigated whether long-term administration of isoproterenol (ISO) induces differential expression of angiotensin-converting enzyme (ACE) in lung, plasma, and left ventricle (LV) during development of left ventricular hypertrophy (LVH) and myocardial fibrosis." | 7.71 | Isoproterenol and angiotensin I-converting enzyme in lung, left ventricle, and plasma during myocardial hypertrophy and fibrosis. ( Chiong, M; Díaz-Araya, G; Ebensperger, R; Irarrázaval, P; Jalil, JE; Lavandero, S; Muñoz, D; Ocaranza, MP; Riveros, JP; Sabat, S, 2002) |
| "Left ventricular hypertrophy due to chronic mechanical systolic pressure overload is not characterized by a deficiency of LV cNOS and cyclic GMP levels." | 7.70 | Chronic L-arginine treatment increases cardiac cyclic guanosine 5'-monophosphate in rats with aortic stenosis: effects on left ventricular mass and beta-adrenergic contractile reserve. ( Bartunek, J; Dempsey, S; Ito, N; Lorell, BH; Rohrbach, S; Tajima, M; Weinberg, EO, 1998) |
| "To evaluate whether the enalaprilat, angiotensin I enzyme conversion inhibitor, could prevent the left ventricular hypertrophy (LVH) induced by isoproterenol." | 7.69 | [Enalaprilat in the prevention of left ventricular hypertrophy induced by isoproterenol]. ( Costa, EA; Ferreira Filho, C; Ferreira, C; Ferreira, M; Luna Filho, B; Murad, N; Póvoa, R, 1997) |
| "We evaluated whether verapamil (VERA) has a protective effect on left ventricular hypertrophy (LVH) induced by Isoproterenol (ISO) in rat." | 7.69 | [Effect of verapamil on left ventricular hypertrophy induced by isoproterenol]. ( Bombig, MT; Brandão, A; Costa, A; Costa, EA; Ferreira, C; Leite, DA; Luna Filho, B; Murad, N; Póvoa, R, 1996) |
| "Treatment with manidipine hydrochloride (once a day at 3 mg/kg) began 1 day before minipump implantation and continued until the end of the experiments (each group; n = 6)." | 5.30 | Effect of manidipine hydrochloride, a calcium antagonist, on isoproterenol-induced left ventricular hypertrophy. ( Akioka, K; Hanatani, A; Iwao, H; Kim, S; Omura, T; Takeuchi, K; Teragaki, M; Toda, I; Yoshikawa, J; Yoshiyama, M, 1998) |
| "Isoproterenol (ISO) was used to induce left ventricular hypertrophy in rats." | 4.31 | Effects of berberine hydrochloride on left ventricular structure and function in rats with myocardial hypertrophy. ( Kou, T; Luo, H; Shen, Y; Su, Y; Yin, L, 2023) |
| "A previous study by our group demonstrated a protective role of the neuropeptide secretoneurin (SN) in DL‑isoproterenol hydrochloride (ISO)‑induced cardiac hypertrophy in mice." | 3.96 | iTRAQ‑based quantitative proteomics analysis of the potential application of secretoneurin gene therapy for cardiac hypertrophy induced by DL‑isoproterenol hydrochloride in mice. ( Chen, H; Jiang, W; Liu, X; Wu, M; Yu, C; Zhang, J, 2020) |
| " This study evaluated whether LCZ696 affects left ventricular hypertrophy, fibrosis, and hemodynamics in isoproterenol (ISO)-treated rats compared with valsartan alone." | 3.91 | Effect of LCZ696, a dual angiotensin receptor neprilysin inhibitor, on isoproterenol-induced cardiac hypertrophy, fibrosis, and hemodynamic change in rats. ( Akagi, S; Ito, H; Kondo, M; Miura, D; Miyoshi, T; Nakamura, K; Ohno, Y; Saito, Y; Yoshida, M, 2019) |
| " Furthermore, the effects of 2-ME on blood pressure and cardiovascular remodeling in the constricted aorta (CA) rat model and on isoproterenol-induced (ISO) cardiac hypertrophy and fibrosis were examined." | 3.91 | 2-Methoxyestradiol Attenuates Angiotensin II-Induced Hypertension, Cardiovascular Remodeling, and Renal Injury. ( Bastacky, SI; Jackson, EK; Salah, E; Tofovic, SP, 2019) |
| "Low-dose rosuvastatin exerted cardioprotective effects on isoproterenol-induced heart failure in rats by modulating DDAH-ADMA-NO pathway, and it may present the new therapeutic value in ameliorating chronic heart failure." | 3.85 | Protective effects of low-dose rosuvastatin on isoproterenol-induced chronic heart failure in rats by regulation of DDAH-ADMA-NO pathway. ( Ma, P; Wang, Y; Xiong, A; Xu, Q; Xu, Y; Zhou, R, 2017) |
| "We aimed to understand the genetic control of cardiac remodeling using an isoproterenol-induced heart failure model in mice, which allowed control of confounding factors in an experimental setting." | 3.83 | Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model. ( Avetisyan, R; Gong, KW; Lusis, AJ; Rau, C; Ren, S; Romay, MC; Stolin, G; Wang, JJ; Wang, Y, 2016) |
| "To elucidate the expression and identify the functional changes of 2 pore domain potassium channel TREK-1 during cardiac hypertrophy in rats, left ventricular hypertrophy was induced by subcutaneous injection with isoproterenol." | 3.79 | An increased TREK-1-like potassium current in ventricular myocytes during rat cardiac hypertrophy. ( Feng, N; Li, P; Peng, Y; Wang, L; Wang, W; Wang, X; Yuan, H; Zhang, M, 2013) |
| "By mimicking sympathetic stimulation in vivo, we previously reported that mice globally lacking serotonin 5-HT(2B) receptors did not develop isoproterenol-induced left ventricular hypertrophy." | 3.75 | Serotonin and angiotensin receptors in cardiac fibroblasts coregulate adrenergic-dependent cardiac hypertrophy. ( Blaxall, BC; Bonnin, P; Callebert, J; Debbabi, H; Doly, S; Jaffré, F; Launay, JM; Maroteaux, L; Mettauer, B; Monassier, L; Setola, V, 2009) |
| "The aim of the present study was performed to determine whether a novel histone deacetylase (HDAC) inhibitor, N-(2-aminophenyl)-4-{[benzyl(2-hydroxyethyl)amino]methyl} benzamide (K-183), prevents a reversible cardiac hypertrophy induced by isoproterenol and improves left ventricular (LV) dysfunction in rats." | 3.74 | Effects of a novel histone deacetylase inhibitor, N-(2-aminophenyl) benzamide, on a reversible hypertrophy induced by isoproterenol in in situ rat hearts. ( Kitagawa, Y; Nakajima-Takenaka, C; Shimizu, J; Takaki, M; Tamura, Y; Taniguchi, S; Uesato, S, 2007) |
| "Gene expression of heparanase, matrix metalloproteinases (MMP)-2 and MMP-9 were examined in ventricles after chronic treatment with isoproterenol (ISO) induced cardiac hypertrophy in rats." | 3.73 | Induction of heparanase gene expression in ventricular myocardium of rats with isoproterenol-induced cardiac hypertrophy. ( Hara, Y; Hashizume, K; Ito, R; Kizaki, K; Mutoh, K; Okada, M; Yoshioka, K, 2005) |
| "This study investigated whether long-term administration of isoproterenol (ISO) induces differential expression of angiotensin-converting enzyme (ACE) in lung, plasma, and left ventricle (LV) during development of left ventricular hypertrophy (LVH) and myocardial fibrosis." | 3.71 | Isoproterenol and angiotensin I-converting enzyme in lung, left ventricle, and plasma during myocardial hypertrophy and fibrosis. ( Chiong, M; Díaz-Araya, G; Ebensperger, R; Irarrázaval, P; Jalil, JE; Lavandero, S; Muñoz, D; Ocaranza, MP; Riveros, JP; Sabat, S, 2002) |
| "To determine whether there are differences in cardiac beta-adrenoceptor responsiveness, isoprenaline affinity constants and fractional beta-adrenoceptor occupancy-response relationships for isoprenaline in the early stages of established hypertension, we studied the effects of bromoacetylalprenololmenthane (BAAM) and ([3,5-diamino-6-chloro-N-(1[N-beta-(2-hydroxyl-3-alpha-naphthoxypropy lamino)ethylcarbamoyl]-1-methylethyl)-pyrazine-2-carboxamide (ICI 147 798), slowly reversible beta-adrenoceptor antagonists, on the isoprenaline responses of the left ventricular papillary muscle and the left and right atria of 6-month-old Wistar Kyoto rats (WKY) and spontaneously hypertensive rats (SHR)." | 3.70 | Affinity constants and beta-adrenoceptor reserves for isoprenaline on cardiac tissue from normotensive and hypertensive rats. ( Barnett, CW; Doggrell, SA; Petcu, EB, 1998) |
| "We tested the hypothesis that changes in phosphorylation of the sarcoplasmic reticulum (SR) protein, phospholamban (PIB) and myofibrillar proteins troponin I (TnI) and C protein are responsible for the decreased relaxant response to isoproterenol in cardiac hypertrophy and failure induced by ascending aortic banding in rats." | 3.70 | Altered phosphorylation of sarcoplasmic reticulum contributes to the diminished contractile response to isoproterenol in hypertrophied rat hearts. ( Belu-John, Y; Morgan, JP; Silverman, M; Strömer, H; Szymanska, G, 1999) |
| "Left ventricular hypertrophy due to chronic mechanical systolic pressure overload is not characterized by a deficiency of LV cNOS and cyclic GMP levels." | 3.70 | Chronic L-arginine treatment increases cardiac cyclic guanosine 5'-monophosphate in rats with aortic stenosis: effects on left ventricular mass and beta-adrenergic contractile reserve. ( Bartunek, J; Dempsey, S; Ito, N; Lorell, BH; Rohrbach, S; Tajima, M; Weinberg, EO, 1998) |
| "The aim of the current study was to determine if lowering myocardial cyclic GMP by guanylate cyclase inhibition would add independently to the positive inotropic effects caused by raising cyclic AMP and if these effects are modified in left ventricular hypertrophy (LVH) produced by aortic valve plication." | 3.70 | Positive inotropy due to lowering cyclic GMP is also mediated by increases in cyclic AMP in control and hypertrophic hearts. ( Leone, RJ; Naim, KL; Rabindranauth, P; Scholz, PM; Tse, J; Weiss, HR, 1998) |
| "We recently demonstrated that rapid ventricular pacing caused cardiac failure (Failure) in dogs with aortic stenosis-induced left ventricular hypertrophy (Hypertrophy) and isoproterenol caused no significant increases in function, O2 consumption and intracellular cyclic AMP level in the failing hypertrophied hearts." | 3.70 | Down regulation of myocardial beta1-adrenoceptor signal transduction system in pacing-induced failure in dogs with aortic stenosis-induced left ventricular hypertrophy. ( He, YQ; Huang, MW; Leone, RJ; Scholz, PM; Tse, J; Weiss, HR, 2000) |
| " To investigate whether inotropic responsiveness is associated with alterations in beta-adrenergic receptors in spontaneously hypertensive rats (SHR), we studied left ventricular myocardial contractile responses to isoproterenol and beta-adrenergic receptor density and affinity in age-matched rats (18 to 24 months), including SHR without heart failure, SHR with evidence of heart failure, and normotensive control Wistar-Kyoto rats (WKY)." | 3.69 | Modulation of left and right ventricular beta-adrenergic receptors from spontaneously hypertensive rats with left ventricular hypertrophy and failure. ( Atkins, FL; Bing, OH; Brooks, WW; Conrad, CH; DiMauro, PG; Robinson, KG, 1995) |
| "To analyze the adrenergic responses and to compare them between hypertensive patients with and without left ventricular hypertrophy (LVH), left ventricular (LV) fractional shortening (FS) and end-systolic wall stress (ESS) were measured by echocardiography and the inotropic response to the infusion of isoproterenol (0." | 3.69 | Decreased adrenergic response in hypertensive patients without left ventricular hypertrophy. ( Fujieda, K; Iida, K; Sugishita, Y; Yukisada, K, 1994) |
| "We evaluated whether verapamil (VERA) has a protective effect on left ventricular hypertrophy (LVH) induced by Isoproterenol (ISO) in rat." | 3.69 | [Effect of verapamil on left ventricular hypertrophy induced by isoproterenol]. ( Bombig, MT; Brandão, A; Costa, A; Costa, EA; Ferreira, C; Leite, DA; Luna Filho, B; Murad, N; Póvoa, R, 1996) |
| "To evaluate whether the enalaprilat, angiotensin I enzyme conversion inhibitor, could prevent the left ventricular hypertrophy (LVH) induced by isoproterenol." | 3.69 | [Enalaprilat in the prevention of left ventricular hypertrophy induced by isoproterenol]. ( Costa, EA; Ferreira Filho, C; Ferreira, C; Ferreira, M; Luna Filho, B; Murad, N; Póvoa, R, 1997) |
| "Hypertension affects about 5% of western populations and in the majority of cases it is of unknown aetiology." | 2.41 | Experimental studies on myocardial stretch and ventricular arrhythmia in hypertrophied and non-hypertrophied hearts. ( Dalton, GR; Evans, SJ; Levi, AJ, 2000) |
| "However, it failed to affect left ventricular hypertrophy and even aggravated the impaired positive and negative lusitropic effects elicited by isoprenaline and carbachol, respectively." | 1.62 | Chronic cannabidiol treatment reduces the carbachol-induced coronary constriction and left ventricular cardiomyocyte width of the isolated hypertensive rat heart. ( Gajo, B; Harasim-Symbor, E; Kasacka, I; Malinowska, B; Pędzińska-Betiuk, A; Schlicker, E; Toczek, M; Weresa, J, 2021) |
| "Pretreatment with zingerone (vanillyl acetone) revealed preventive effects on tachycardia, LVH, ECG, and all the above mentioned biochemical parameters evaluated in isoproterenol induced myocardial infarcted rats." | 1.42 | A biochemical and 2, 3, 5-triphenyl tetrazolium chloride staining study on the preventive effects of zingerone (vanillyl acetone) in experimentally induced myocardial infarcted rats. ( Hemalatha, KL; Stanely Mainzen Prince, P, 2015) |
| "There were no group differences in left ventricular hypertrophy, apoptosis, and fibrosis." | 1.39 | Adenylyl cyclase 6 deletion increases mortality during sustained β-adrenergic receptor stimulation. ( Gao, MH; Guo, T; Hammond, HK; Lai, NC; Lee, P; McCulloch, AD; Tang, R; Tang, T; Wright, AT, 2013) |
| "Enalapril treatment significantly prevented hypertrophy, apoptosis, and CaMKII activity." | 1.38 | Early apoptosis in different models of cardiac hypertrophy induced by high renin-angiotensin system activity involves CaMKII. ( Mattiazzi, A; Palomeque, J; Velez Rueda, JO, 2012) |
| "Whereas ISO/PE induced left ventricular hypertrophy (LVH) with increased posterior wall thickness to a similar extent in all groups, it increased septum thickness only in Het-KI and Het-KO." | 1.38 | Adrenergic stress reveals septal hypertrophy and proteasome impairment in heterozygous Mybpc3-targeted knock-in mice. ( Carrier, L; Eschenhagen, T; Geertz, B; Mearini, G; Schlossarek, S; Schuermann, F, 2012) |
| "The ventricular remodeling of mice were induced by subcutaneous injection of ISO with the dosage of 2 mg/kg daily for 7 d and the rats with L-Thy intraperitoneally with the dosage of 0." | 1.36 | [Effect of Chrysanthemum indicum on ventricular remodeling in rats]. ( Chen, CX; Gao, JP; Gu, WL; Lv, J; Wan, Y; Wu, Q, 2010) |
| "Current research in left ventricular hypertrophy (LVH) has largely focused on its progression and therapeutic mechanisms to prevent or slow its development." | 1.35 | Proteasome inhibition promotes regression of left ventricular hypertrophy. ( Baldwin, AS; Moss, NC; Selzman, CH; Stansfield, WE; Tang, RH; Willis, MS, 2008) |
| "Isoproterenol treatment for 1 week resulted in 36% and 44% (P<0." | 1.33 | Chronic beta-adrenoceptor stimulation and cardiac hypertrophy with no induction of circulating renin. ( Krieger, JE; Oliveira, EM, 2005) |
| "Left ventricular hypertrophy was induced by a 50% constriction of suprarenal abdominal aorta for 6 weeks." | 1.33 | Cardiac hypertrophy diminished the effects of isoproterenol on delayed rectifier potassium current in rat heart. ( Mani, H; Matsubara, H; Sakatani, T; Shiraishi, H; Shirayama, T; Yamamoto, T, 2006) |
| "Severity of left ventricular hypertrophy (LVH) correlates with elevated plasma levels of neuropeptide Y (NPY) in hypertension." | 1.33 | Modulation of contractile function through neuropeptide Y receptors during development of cardiomyocyte hypertrophy. ( Allen, AR; Bell, D; Dickson, P; Kelso, EJ; McDermott, BJ; Zhao, Y, 2006) |
| "Infarct-induced heart failure is usually associated with cardiac hypertrophy and decreased -adrenergic responsiveness." | 1.32 | Impaired beta-adrenergic response and decreased L-type calcium current of hypertrophied left ventricular myocytes in postinfarction heart failure. ( Chedid, NG; Díaz G, LE; Masuda, MO; Quintero H, CC; Saraiva, RM, 2003) |
| "Chronic treatment of renovascular hypertension with captopril can restore normal responsiveness of I(Ca,L) to (+/-)-isoproterenol in cardiac myocytes." | 1.31 | Effects of captopril treatment of renovascular hypertension on beta-adrenergic modulation of L-type Ca(2+) current. ( Kowey, PR; Liu, T; Marinchak, RA; Rials, SJ; Wu, Y; Xu, X, 2000) |
| "Left ventricular hypertrophy was induced in guinea-pigs by constriction of the thoracic aorta." | 1.31 | The action of isoprenaline on the electrophysiological properties of hypertrophied left ventricular myocytes. ( Cooklin, M; Fry, CH; Sheridan, DJ; Wallis, W, 2001) |
| "In conclusion, left ventricular hypertrophy in young essential hypertensives is associated to a reduced beta2-adrenoceptor density and function, probably as a compensating mechanism of the hypertrophied myocardiocyte secondary to the increased sympathetic outflow." | 1.31 | Beta-adrenergic receptor density and function in left ventricular hypertrophy in young essential hypertensives. ( Azqueta, M; Calls, J; Cases, A; Esforzado, N; Jimenez, W; Lario, S; Paré, JC; Rivera-Fillat, F, 2000) |
| "The transition from compensated left ventricular hypertrophy (LVH) to heart failure is associated with alterations in the myocardial interstitium." | 1.31 | Reduction in myocardial collagen cross-linking parallels left ventricular dilatation in rat models of systolic chamber dysfunction. ( Chung, ES; Lancaster, EJ; Mela, T; Meyer, TE; Norton, GR; Sprott, S; Tsotetsi, OJ; Woodiwiss, AJ, 2001) |
| "TGR rats showed left ventricular hypertrophy (54%), higher blood pressures (76 mmHg), and elevated plasma renin activity (seven-fold) compared to controls (P < 0." | 1.31 | Myocardial adrenergic dysfunction in rats with transgenic, human renin-dependent hypertension. ( Bartel, S; Bohlender, J; Günther, J; Hempel, P; Hildenbrand, U; Krause, EG; Luft, FC; Schlegel, WP; Wagner, KD, 2001) |
| "Treatment with manidipine hydrochloride (once a day at 3 mg/kg) began 1 day before minipump implantation and continued until the end of the experiments (each group; n = 6)." | 1.30 | Effect of manidipine hydrochloride, a calcium antagonist, on isoproterenol-induced left ventricular hypertrophy. ( Akioka, K; Hanatani, A; Iwao, H; Kim, S; Omura, T; Takeuchi, K; Teragaki, M; Toda, I; Yoshikawa, J; Yoshiyama, M, 1998) |
| "Left ventricular hypertrophy was defined as an inter-ventricular thickness or posterior wall thickness > or = 13 mm." | 1.29 | Pathophysiologic significance of left ventricular hypertrophy in dilated cardiomyopathy. ( el Sersi, M; Fujieda, K; Iida, K; Iwasaki, Y; Kawano, S; Masumi, T; Sugishita, Y; Tabei, F; Yamaguchi, I, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 22 (20.37) | 18.2507 |
| 2000's | 50 (46.30) | 29.6817 |
| 2010's | 31 (28.70) | 24.3611 |
| 2020's | 5 (4.63) | 2.80 |
| Authors | Studies |
|---|---|
| Kou, T | 1 |
| Luo, H | 1 |
| Shen, Y | 1 |
| Su, Y | 1 |
| Yin, L | 1 |
| Chen, H | 1 |
| Wu, M | 1 |
| Jiang, W | 1 |
| Liu, X | 1 |
| Zhang, J | 2 |
| Yu, C | 1 |
| Sun, TL | 1 |
| Li, WQ | 1 |
| Tong, XL | 1 |
| Liu, XY | 1 |
| Zhou, WH | 1 |
| Pędzińska-Betiuk, A | 1 |
| Weresa, J | 1 |
| Schlicker, E | 1 |
| Harasim-Symbor, E | 1 |
| Toczek, M | 1 |
| Kasacka, I | 1 |
| Gajo, B | 1 |
| Malinowska, B | 1 |
| Garrott, K | 1 |
| Dyavanapalli, J | 1 |
| Cauley, E | 1 |
| Dwyer, MK | 1 |
| Kuzmiak-Glancy, S | 1 |
| Wang, X | 2 |
| Mendelowitz, D | 1 |
| Kay, MW | 1 |
| Ahmad, A | 3 |
| Sattar, M | 1 |
| Khan, SA | 3 |
| Abdullah, NA | 3 |
| Johns, EJ | 3 |
| Afzal, S | 1 |
| Miyoshi, T | 2 |
| Nakamura, K | 2 |
| Miura, D | 2 |
| Yoshida, M | 1 |
| Saito, Y | 1 |
| Akagi, S | 1 |
| Ohno, Y | 1 |
| Kondo, M | 1 |
| Ito, H | 3 |
| Ali, SS | 1 |
| Mohamed, SFA | 1 |
| Rozalei, NH | 1 |
| Boon, YW | 1 |
| Zainalabidin, S | 1 |
| Salah, E | 1 |
| Bastacky, SI | 1 |
| Jackson, EK | 1 |
| Tofovic, SP | 1 |
| Aluja, D | 1 |
| Inserte, J | 1 |
| Penela, P | 1 |
| Ramos, P | 1 |
| Ribas, C | 1 |
| Iñiguez, MÁ | 1 |
| Mayor, F | 1 |
| Garcia-Dorado, D | 1 |
| Zou, J | 1 |
| Ma, W | 1 |
| Littlejohn, R | 1 |
| Li, J | 2 |
| Stansfield, BK | 1 |
| Kim, IM | 1 |
| Liu, J | 1 |
| Zhou, J | 1 |
| Weintraub, NL | 1 |
| Su, H | 1 |
| Hu, H | 1 |
| Jiang, M | 2 |
| Cao, Y | 1 |
| Zhang, Z | 1 |
| Jiang, B | 1 |
| Tian, F | 1 |
| Feng, J | 1 |
| Dou, Y | 1 |
| Gorospe, M | 1 |
| Zheng, M | 1 |
| Zheng, L | 1 |
| Yang, Z | 1 |
| Wang, W | 2 |
| Tang, T | 1 |
| Lai, NC | 1 |
| Wright, AT | 1 |
| Gao, MH | 1 |
| Lee, P | 1 |
| Guo, T | 1 |
| Tang, R | 1 |
| McCulloch, AD | 1 |
| Hammond, HK | 1 |
| Yang, J | 2 |
| Wang, HX | 1 |
| Zhang, YJ | 1 |
| Yang, YH | 1 |
| Lu, ML | 1 |
| Li, ST | 1 |
| Zhang, SP | 1 |
| Li, G | 1 |
| Aflaki, M | 1 |
| Qi, XY | 1 |
| Xiao, L | 1 |
| Ordog, B | 1 |
| Tadevosyan, A | 1 |
| Luo, X | 1 |
| Maguy, A | 1 |
| Shi, Y | 1 |
| Tardif, JC | 1 |
| Nattel, S | 1 |
| Sattar, MA | 2 |
| Rathore, HA | 2 |
| Abdulla, MH | 2 |
| Kaur, G | 1 |
| Hemalatha, KL | 1 |
| Stanely Mainzen Prince, P | 1 |
| Jacobs, G | 1 |
| Oosterlinck, W | 1 |
| Dresselaers, T | 1 |
| Geenens, R | 1 |
| Kerselaers, S | 1 |
| Himmelreich, U | 1 |
| Herijgers, P | 1 |
| Vennekens, R | 1 |
| Al-Rasheed, NM | 2 |
| Bassiouni, YA | 1 |
| Hasan, IH | 1 |
| Al-Amin, MA | 1 |
| Al-Ajmi, HN | 1 |
| Mohamad, RA | 1 |
| Azam, M | 1 |
| Wang, JJ | 1 |
| Rau, C | 1 |
| Avetisyan, R | 1 |
| Ren, S | 1 |
| Romay, MC | 1 |
| Stolin, G | 1 |
| Gong, KW | 1 |
| Wang, Y | 3 |
| Lusis, AJ | 1 |
| Zhou, R | 1 |
| Ma, P | 1 |
| Xiong, A | 1 |
| Xu, Y | 1 |
| Xu, Q | 1 |
| Koch, SE | 1 |
| Mann, A | 1 |
| Jones, S | 1 |
| Robbins, N | 1 |
| Alkhattabi, A | 1 |
| Worley, MC | 1 |
| Gao, X | 1 |
| Lasko-Roiniotis, VM | 1 |
| Karani, R | 1 |
| Fulford, L | 1 |
| Nieman, M | 1 |
| Lorenz, JN | 1 |
| Rubinstein, J | 1 |
| Zarrinpashneh, E | 1 |
| Beauloye, C | 1 |
| Ginion, A | 1 |
| Pouleur, AC | 1 |
| Havaux, X | 1 |
| Hue, L | 1 |
| Viollet, B | 1 |
| Vanoverschelde, JL | 1 |
| Bertrand, L | 1 |
| Jaffré, F | 1 |
| Bonnin, P | 1 |
| Callebert, J | 1 |
| Debbabi, H | 1 |
| Setola, V | 1 |
| Doly, S | 1 |
| Monassier, L | 1 |
| Mettauer, B | 1 |
| Blaxall, BC | 1 |
| Launay, JM | 1 |
| Maroteaux, L | 1 |
| Bhuiyan, MS | 2 |
| Shioda, N | 2 |
| Shibuya, M | 1 |
| Iwabuchi, Y | 1 |
| Fukunaga, K | 2 |
| Hibuse, T | 1 |
| Maeda, N | 1 |
| Nakatsuji, H | 1 |
| Tochino, Y | 1 |
| Fujita, K | 1 |
| Kihara, S | 1 |
| Funahashi, T | 1 |
| Shimomura, I | 1 |
| Mikusová, A | 1 |
| Králová, E | 2 |
| Tylková, L | 1 |
| Novotová, M | 1 |
| Stankovicová, T | 2 |
| Heather, LC | 1 |
| Catchpole, AF | 1 |
| Stuckey, DJ | 1 |
| Cole, MA | 1 |
| Carr, CA | 1 |
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2 reviews available for isoproterenol and Left Ventricular Hypertrophy
| Article | Year |
|---|---|
Experimental studies on myocardial stretch and ventricular arrhythmia in hypertrophied and non-hypertrophied hearts.
Topics: Animals; Arrhythmias, Cardiac; Calcium; Calcium Channel Blockers; Cardiotonic Agents; Death, Sudden, | 2000 |
Old and new tools to dissect calcineurin's role in pressure-overload cardiac hypertrophy.
Topics: A Kinase Anchor Proteins; Adaptor Proteins, Signal Transducing; Adrenergic beta-Agonists; Animals; A | 2002 |
1 trial available for isoproterenol and Left Ventricular Hypertrophy
| Article | Year |
|---|---|
Impaired force-frequency relations in patients with hypertensive left ventricular hypertrophy. A possible physiological marker of the transition from physiological to pathological hypertrophy.
Topics: Adrenergic beta-Agonists; Adult; Biomarkers; Cardiac Pacing, Artificial; Epinephrine; Exercise; Hear | 1999 |
105 other studies available for isoproterenol and Left Ventricular Hypertrophy
| Article | Year |
|---|---|
Effects of berberine hydrochloride on left ventricular structure and function in rats with myocardial hypertrophy.
Topics: Animals; Berberine; Humans; Hypertrophy, Left Ventricular; Isoproterenol; Rats; Transforming Growth | 2023 |
iTRAQ‑based quantitative proteomics analysis of the potential application of secretoneurin gene therapy for cardiac hypertrophy induced by DL‑isoproterenol hydrochloride in mice.
Topics: Animals; Blotting, Western; Cardiomegaly; Echocardiography; Genetic Therapy; Hemodynamics; Hypertrop | 2020 |
Xanthohumol attenuates isoprenaline-induced cardiac hypertrophy and fibrosis through regulating PTEN/AKT/mTOR pathway.
Topics: Animals; Disease Models, Animal; Fibrosis; Flavonoids; Hypertrophy, Left Ventricular; Isoproterenol; | 2021 |
Chronic cannabidiol treatment reduces the carbachol-induced coronary constriction and left ventricular cardiomyocyte width of the isolated hypertensive rat heart.
Topics: Adrenergic beta-Agonists; Animals; Antihypertensive Agents; Cannabidiol; Carbachol; Cell Size; Coron | 2021 |
Chronic activation of hypothalamic oxytocin neurons improves cardiac function during left ventricular hypertrophy-induced heart failure.
Topics: Animals; Heart; Heart Failure; Hypertrophy, Left Ventricular; Isoproterenol; Male; Myocardial Contra | 2017 |
INCREASED OXIDATIVE STRESS AND DOWN REGULATION OF ENDOTHELIAL NITRIC OXIDE SYNTHASE (ENOS) IN THE KIDNEY ATTEN- UATE THE RESPONSIVENESS OF (XlB ADRENERGIC RECEPTORS IN THE KIDNEY OF RATS WITH LEFT VENTRICULAR HYPERTROPHY.
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Caffeine; Disease Models, Animal; Dose-Response Relat | 2017 |
Effect of LCZ696, a dual angiotensin receptor neprilysin inhibitor, on isoproterenol-induced cardiac hypertrophy, fibrosis, and hemodynamic change in rats.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Disease Models, Anima | 2019 |
Anti-fibrotic Actions of Roselle Extract in Rat Model of Myocardial Infarction.
Topics: Animals; Atrial Natriuretic Factor; Cardiovascular Agents; Collagen Type I; Collagen Type III; Disea | 2019 |
2-Methoxyestradiol Attenuates Angiotensin II-Induced Hypertension, Cardiovascular Remodeling, and Renal Injury.
Topics: 2-Methoxyestradiol; Angiotensin II; Animals; Blood Pressure; Fibrosis; Glomerular Filtration Rate; H | 2019 |
Calpains mediate isoproterenol-induced hypertrophy through modulation of GRK2.
Topics: Animals; Calpain; Carbamates; Disease Models, Animal; G-Protein-Coupled Receptor Kinase 2; Hypertrop | 2019 |
Transient inhibition of neddylation at neonatal stage evokes reversible cardiomyopathy and predisposes the heart to isoproterenol-induced heart failure.
Topics: Animals; Animals, Newborn; Cell Proliferation; Cells, Cultured; Cyclopentanes; Disease Models, Anima | 2019 |
HuR regulates phospholamban expression in isoproterenol-induced cardiac remodelling.
Topics: Animals; Calcium Signaling; Calcium-Binding Proteins; Cell Line; Disease Models, Animal; ELAV-Like P | 2020 |
Adenylyl cyclase 6 deletion increases mortality during sustained β-adrenergic receptor stimulation.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Connexin 43; Cyclic AMP; Gene Deletion; Hypert | 2013 |
Astragaloside IV attenuates inflammatory cytokines by inhibiting TLR4/NF-кB signaling pathway in isoproterenol-induced myocardial hypertrophy.
Topics: Animals; Anti-Inflammatory Agents; Cardiotonic Agents; Cells, Cultured; Hypertrophy, Left Ventricula | 2013 |
Exchange protein directly activated by cAMP mediates slow delayed-rectifier current remodeling by sustained β-adrenergic activation in guinea pig hearts.
Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Calcineurin; Calcium; Cells, Cultured; Colfors | 2014 |
Functional contribution of α1D-adrenoceptors in the renal vasculature of left ventricular hypertrophy induced with isoprenaline and caffeine in Wistar-Kyoto rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Arterial Pressure; Caffeine; Hemodynamics; Hypertr | 2014 |
A biochemical and 2, 3, 5-triphenyl tetrazolium chloride staining study on the preventive effects of zingerone (vanillyl acetone) in experimentally induced myocardial infarcted rats.
Topics: Adenosine Triphosphatases; Animals; Biomarkers; Coloring Agents; Disease Models, Animal; Electrocard | 2015 |
Enhanced β-adrenergic cardiac reserve in Trpm4⁻/⁻ mice with ischaemic heart failure.
Topics: Adrenergic beta-Agonists; Animals; Electrocardiography; Heart Failure; Hypertrophy, Left Ventricular | 2015 |
Vitamin D attenuates pro-inflammatory TNF-α cytokine expression by inhibiting NF-кB/p65 signaling in hypertrophied rat hearts.
Topics: Animals; Body Weight; Cardiotonic Agents; Cholecalciferol; Hypertrophy, Left Ventricular; I-kappa B | 2015 |
Up Regulation of cystathione γ lyase and Hydrogen Sulphide in the Myocardium Inhibits the Progression of Isoproterenol-Caffeine Induced Left Ventricular Hypertrophy in Wistar Kyoto Rats.
Topics: Animals; Caffeine; Cystathionine gamma-Lyase; Gene Expression Regulation, Enzymologic; Hydrogen Sulf | 2016 |
Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model.
Topics: Animals; Disease Models, Animal; Echocardiography; Galectin 3; Gene Expression Regulation; Heart Fai | 2016 |
Protective effects of low-dose rosuvastatin on isoproterenol-induced chronic heart failure in rats by regulation of DDAH-ADMA-NO pathway.
Topics: Amidohydrolases; Animals; Biomarkers; Cardiotonic Agents; Disease Models, Animal; Fibrosis; Heart Fa | 2017 |
Transient receptor potential vanilloid 2 function regulates cardiac hypertrophy via stretch-induced activation.
Topics: Adrenergic beta-Agonists; Angiotensin II; Animals; Aorta; Calcium Channels; Constriction, Pathologic | 2017 |
AMPKalpha2 counteracts the development of cardiac hypertrophy induced by isoproterenol.
Topics: AMP-Activated Protein Kinases; Animals; Hypertrophy, Left Ventricular; Isoproterenol; Mice; Mice, Kn | 2008 |
Serotonin and angiotensin receptors in cardiac fibroblasts coregulate adrenergic-dependent cardiac hypertrophy.
Topics: Adult; Angiotensin II; Animals; Cells, Cultured; Cytokines; ErbB Receptors; Female; Fibroblasts; Hea | 2009 |
Activation of endothelial nitric oxide synthase by a vanadium compound ameliorates pressure overload-induced cardiac injury in ovariectomized rats.
Topics: Animals; Blood Pressure; Calcium-Binding Proteins; Cardiotonic Agents; Disease Models, Animal; Dose- | 2009 |
The heart requires glycerol as an energy substrate through aquaporin 7, a glycerol facilitator.
Topics: Adenosine Triphosphate; Animals; Aquaglyceroporins; Aquaporins; Cardiotonic Agents; Energy Metabolis | 2009 |
Myocardial remodelling induced by repeated low doses of isoproterenol.
Topics: Animals; Cardiotonic Agents; Drug Administration Schedule; Hemodynamics; Hypertrophy, Left Ventricul | 2009 |
Isoproterenol induces in vivo functional and metabolic abnormalities: similar to those found in the infarcted rat heart.
Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Disease Models, Animal; Fatty Acid Transport Prot | 2009 |
Myoglobin-deficient mice activate a distinct cardiac gene expression program in response to isoproterenol-induced hypertrophy.
Topics: Adaptation, Physiological; Animals; Cluster Analysis; Disease Models, Animal; Gene Expression Profil | 2010 |
Impact of aldosterone receptor blockade on the deleterious cardiac effects of adrenergic activation in hypertensive rats.
Topics: Adrenergic beta-Agonists; Animals; Apoptosis; Blood Pressure; Cardiomyopathy, Dilated; Hypertension; | 2010 |
Effects of cardiac overexpression of type 6 adenylyl cyclase affects on the response to chronic pressure overload.
Topics: Adenylyl Cyclases; Analysis of Variance; Animals; Apoptosis; Colforsin; Echocardiography; Heart; Hea | 2010 |
Effects of polydatin on attenuating ventricular remodeling in isoproterenol-induced mouse and pressure-overload rat models.
Topics: Aldosterone; Angiotensin II; Animals; Aorta, Abdominal; Blood Pressure; Cardiovascular Agents; Colla | 2010 |
Oligomerized grape seed proanthocyanidins ameliorates isoproterenol-induced cardiac remodeling in rats: role of oxidative stress.
Topics: Animals; Antioxidants; Cardiotonic Agents; Cyclooxygenase 2; Disease Models, Animal; Grape Seed Extr | 2011 |
[Effect of Chrysanthemum indicum on ventricular remodeling in rats].
Topics: Aldosterone; Angiotensin II; Animals; Chrysanthemum; Disease Models, Animal; Drugs, Chinese Herbal; | 2010 |
Adrenergic stress reveals septal hypertrophy and proteasome impairment in heterozygous Mybpc3-targeted knock-in mice.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Alleles; Animals; Cardiomyopathy, Hypertrophic; | 2012 |
NHE-1 blockade reversed changes in calcium transient in myocardial slices from isoproterenol-induced hypertrophied rat left ventricle.
Topics: Animals; Calcium; Cells, Cultured; Guanidines; Hypertrophy, Left Ventricular; Isoproterenol; Male; M | 2012 |
Early apoptosis in different models of cardiac hypertrophy induced by high renin-angiotensin system activity involves CaMKII.
Topics: Aldosterone; Animals; Apoptosis; Blood Pressure; Calcium; Calcium-Calmodulin-Dependent Protein Kinas | 2012 |
Granulocyte colony-stimulating factor improves early remodeling in isoproterenol-induced cardiac injury in rats.
Topics: Animals; Collagen; Dilatation, Pathologic; Disease Models, Animal; Echocardiography; Fibrosis; Granu | 2012 |
Prion protein as a mediator of neurocardiosympathetic interactions.
Topics: Analysis of Variance; Animals; Blotting, Western; Brain; Brain Chemistry; Echocardiography; Hypertro | 2012 |
Increased passive stiffness of cardiomyocytes in the transverse direction and residual actin and myosin cross-bridge formation in hypertrophied rat hearts induced by chronic β-adrenergic stimulation.
Topics: Actins; Adrenergic beta-Agonists; Animals; Cardiomegaly; Cells, Cultured; Diacetyl; Disease Models, | 2013 |
An increased TREK-1-like potassium current in ventricular myocytes during rat cardiac hypertrophy.
Topics: Animals; Benzofurans; Blotting, Western; CHO Cells; Cricetinae; Cricetulus; Disease Models, Animal; | 2013 |
Isoproterenol and angiotensin I-converting enzyme in lung, left ventricle, and plasma during myocardial hypertrophy and fibrosis.
Topics: Animals; Cardiotonic Agents; Fibrosis; Hemodynamics; Hypertrophy, Left Ventricular; Isoproterenol; L | 2002 |
Beta-adrenergic activation initiates chamber dilatation in concentric hypertrophy.
Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Body Weight; Collagen; Dilatation, Pathologic; Di | 2003 |
Cardiomegaly induced by pressure overload in newborn rats is accompanied by altered expression of the long isoform of G(s)alpha protein and deranged signaling of adenylyl cyclase.
Topics: Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Cardiomegaly; Cardiotonic Agents; Colforsin; Fl | 2003 |
Impaired beta-adrenergic response and decreased L-type calcium current of hypertrophied left ventricular myocytes in postinfarction heart failure.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Calcium Channels, L-Type; Colforsin; Disease M | 2003 |
Changes in the Ca2+-activated K+ channels of the coronary artery during left ventricular hypertrophy.
Topics: Animals; Cells, Cultured; Coronary Vessels; Electric Conductivity; Hypertrophy, Left Ventricular; Is | 2003 |
Beta-adrenergic stimulation induces cardiac ankyrin repeat protein expression: involvement of protein kinase A and calmodulin-dependent kinase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenergic beta-Agonists; Animals; Blotting, Northern | 2003 |
Cardiomyocyte-specific overexpression of nitric oxide synthase 3 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction.
Topics: Adrenergic beta-Agonists; Animals; Enzyme Induction; Fibrosis; Humans; Hypertrophy; Hypertrophy, Lef | 2004 |
Re: Regulation of protein kinase C isozyme and calcineurin expression in isoproterenol-induced cardiac hypertrophy.
Topics: Animals; Calcineurin; Hypertrophy, Left Ventricular; Isoenzymes; Isoproterenol; Protein Kinase C; Ra | 2004 |
A phosphodiesterase inhibitor promotes the premature development of adverse cardiac remodelling mediated by beta-adrenergic activation in hypertension.
Topics: Adrenergic beta-Agonists; Animals; Collagen; Dilatation, Pathologic; Drug Therapy, Combination; Echo | 2004 |
Down-regulation of Na+ pump alpha 2 isoform in isoprenaline-induced cardiac hypertrophy in rat: evidence for increased receptor binding affinity but reduced inotropic potency of digoxin.
Topics: Animals; Digoxin; Disease Models, Animal; Down-Regulation; Hypertrophy, Left Ventricular; Isoprotere | 2005 |
Aldosterone receptor blockade prevents the transition to cardiac pump dysfunction induced by beta-adrenoreceptor activation.
Topics: Adrenergic beta-Agonists; Animals; Collagen; Echocardiography; Heart; Hypertension; Hypertrophy, Lef | 2005 |
Improved myocardial beta-adrenergic responsiveness and signaling with exercise training in hypertension.
Topics: Adrenergic beta-Agonists; Animals; beta-Adrenergic Receptor Kinases; Blood Pressure; Calcium Channel | 2005 |
Chronic beta-adrenoceptor stimulation and cardiac hypertrophy with no induction of circulating renin.
Topics: Adrenergic beta-Agonists; Animals; Atrial Natriuretic Factor; Cardiac Output; Gene Expression Regula | 2005 |
Mechanisms of preserved baseline cardiac systolic function in rats with adrenergic inotropic downregulation.
Topics: Adrenergic beta-Agonists; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Re | 2005 |
Lack of inducible NO synthase reduces oxidative stress and enhances cardiac response to isoproterenol in mice with deoxycorticosterone acetate-salt hypertension.
Topics: Aldehydes; Animals; Blood Pressure; Cardiotonic Agents; Desoxycorticosterone; Heart; Hypertension; H | 2005 |
Induction of heparanase gene expression in ventricular myocardium of rats with isoproterenol-induced cardiac hypertrophy.
Topics: Animals; Blotting, Northern; Cardiomegaly; Disease Models, Animal; Drug Administration Schedule; Enz | 2005 |
Heart failure reduces both the effects and interaction between cyclic GMP and cyclic AMP.
Topics: Animals; Cardiac Output, Low; Cardiotonic Agents; Coronary Circulation; Coronary Vessels; Cyclic AMP | 2006 |
Enhanced acidotic myocardial Ca2+ responsiveness with training in hypertension.
Topics: Acidosis; Animals; Blood Pressure; Calcium; Female; Heart Rate; Hypertrophy, Left Ventricular; Isopr | 2006 |
Enhanced isoproterenol-induced cardiac hypertrophy in transgenic rats with low brain angiotensinogen.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Angiotensinogen; Animals; Animals, Geneticall | 2006 |
Cardiac hypertrophy diminished the effects of isoproterenol on delayed rectifier potassium current in rat heart.
Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Adrenergic beta-Agonists; Animals; Calcium Channels, | 2006 |
Temporal patterns of electrical remodeling in canine ventricular hypertrophy: focus on IKs downregulation and blunted beta-adrenergic activation.
Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Blotting, Western; Chromans; Dogs; Down-Reg | 2006 |
Modulation of contractile function through neuropeptide Y receptors during development of cardiomyocyte hypertrophy.
Topics: Animals; Arginine; Calcium; Cardiotonic Agents; Cell Differentiation; Cell Separation; Cell Size; El | 2006 |
Death, cardiac dysfunction, and arrhythmias are increased by calmodulin kinase II in calcineurin cardiomyopathy.
Topics: Amino Acid Sequence; Animals; Animals, Newborn; Apoptosis; Arrhythmias, Cardiac; Benzylamines; Calci | 2006 |
Site specific differential activation of ras/raf/ERK signaling in rabbit isoproterenol-induced left ventricular hypertrophy.
Topics: Adrenergic beta-Agonists; Animals; Cerebral Arteries; Cyclic AMP-Dependent Protein Kinases; Enzyme A | 2006 |
Effects of a novel histone deacetylase inhibitor, N-(2-aminophenyl) benzamide, on a reversible hypertrophy induced by isoproterenol in in situ rat hearts.
Topics: Analysis of Variance; Animals; Benzamides; Cardiac Catheterization; Cardiac Output; Cardiomegaly; Co | 2007 |
Ovariectomy augments pressure overload-induced hypertrophy associated with changes in Akt and nitric oxide synthase signaling pathways in female rats.
Topics: Animals; Aorta, Abdominal; Aortic Valve Stenosis; Blood Pressure; Body Weight; Caveolin 3; Dystrophi | 2007 |
Serotonin responsiveness through 5-HT2A and 5-HT4 receptors is differentially regulated in hypertrophic and failing rat cardiac ventricle.
Topics: Animals; Echocardiography; Gene Expression Regulation; Heart Failure; Heart Ventricles; Humans; Hype | 2007 |
Proteasome inhibition promotes regression of left ventricular hypertrophy.
Topics: Animals; Blotting, Western; Body Weight; Cardiotonic Agents; Cell Nucleus; Disease Progression; Echo | 2008 |
Electrocardiography in two models of isoproterenol-induced left ventricular remodeling.
Topics: Action Potentials; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Electrocardiog | 2008 |
Isoproterenol-induced hypertrophied rat hearts: does short-term treatment correspond to long-term treatment?
Topics: Animals; Blood Pressure; Blotting, Western; Cardiac Volume; Cardiotonic Agents; Disease Models, Anim | 2008 |
[Left ventricular hypertrophy: its prevention with enalapril].
Topics: Analysis of Variance; Animals; Drug Evaluation, Preclinical; Enalapril; Hypertrophy, Left Ventricula | 1995 |
Cardiac hypertrophy induced by alpha- and beta-adrenergic receptor stimulation.
Topics: Animals; Disease Models, Animal; Female; Glucosephosphate Dehydrogenase; Hemodynamics; Hypertrophy, | 1995 |
Modulation of left and right ventricular beta-adrenergic receptors from spontaneously hypertensive rats with left ventricular hypertrophy and failure.
Topics: Animals; Biochemical Phenomena; Biochemistry; Colforsin; Heart Failure; Heart Ventricles; Hypertensi | 1995 |
Effects of isoprenaline on force of contraction, cAMP content, and phosphorylation of regulatory proteins in hearts from chronic beta-adrenergic-stimulated rats.
Topics: Adenosine Triphosphatases; Animals; Calcium-Binding Proteins; Carrier Proteins; Cyclic AMP; Hypertro | 1995 |
Neurohumoral factors during transition from left ventricular hypertrophy to failure in Dahl salt-sensitive rats.
Topics: Animals; Atrial Natriuretic Factor; Calcium; Heart Failure; Hypertrophy, Left Ventricular; Isoproter | 1995 |
Decreased adrenergic response in hypertensive patients without left ventricular hypertrophy.
Topics: Adult; Analysis of Variance; Echocardiography; Female; Hemodynamics; Humans; Hypertension; Hypertrop | 1994 |
Beta adrenergic and muscarinic receptors in compensatory cardiac hypertrophy of the adult rat.
Topics: Adenylyl Cyclases; Animals; Aortic Valve Stenosis; Body Weight; Carbachol; Cyclic AMP; Hypertrophy, | 1993 |
Inhibition of nitric oxide synthesis reduces coronary blood flow response but does not increase cardiac contractile response to beta-adrenergic stimulation in normal dogs.
Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Coronary Circulation; Dogs; Female; Heart Rate; He | 1996 |
Pathophysiologic significance of left ventricular hypertrophy in dilated cardiomyopathy.
Topics: Adult; Aged; Cardiomyopathy, Dilated; Cardiotonic Agents; Catecholamines; Female; Humans; Hypertroph | 1996 |
[Effect of verapamil on left ventricular hypertrophy induced by isoproterenol].
Topics: Animals; Calcium Channel Blockers; Cardiotonic Agents; Collagen; Heart Ventricles; Hypertrophy, Left | 1996 |
[The expression of nucleolar organizer regions in left ventricular hypertrophy].
Topics: Analysis of Variance; Animals; Cardiotonic Agents; Hypertrophy, Left Ventricular; Isoproterenol; Mal | 1997 |
[Left ventricular hypertrophy--its reversion speeded up by enalaprilat].
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiotonic Agents; Drug Evaluation, Preclinical; | 1997 |
Progression of left ventricular hypertrophy does not change the sarcoplasmic reticulum calcium store in the spontaneously hypertensive rat heart.
Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Body Weight; Calcium; Dose-Response Relationship, | 1997 |
Effects of chronic angiotensin-converting enzyme inhibition on left ventricular and myocyte structure and function during recovery from chronic rapid pacing.
Topics: Adrenergic beta-Agonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiac Pacing, Artific | 1997 |
Affinity constants and beta-adrenoceptor reserves for isoprenaline on cardiac tissue from normotensive and hypertensive rats.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alprenolol; Animals; Female; Heart; Heart Atr | 1998 |
[Enalaprilat in the prevention of left ventricular hypertrophy induced by isoproterenol].
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Enalaprilat; Hypertrophy, Left Ventricular; Isopr | 1997 |
Effect of manidipine hydrochloride, a calcium antagonist, on isoproterenol-induced left ventricular hypertrophy.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Blotting, Northern; Body Weight; Calcium Channel | 1998 |
Chronic L-arginine treatment increases cardiac cyclic guanosine 5'-monophosphate in rats with aortic stenosis: effects on left ventricular mass and beta-adrenergic contractile reserve.
Topics: Adrenergic beta-Agonists; Animals; Aortic Valve Stenosis; Arginine; Blood Pressure; Calcium; Case-Co | 1998 |
beta-adrenergic stimulation causes cardiocyte apoptosis: influence of tachycardia and hypertrophy.
Topics: Adrenergic beta-Agonists; Animals; Aorta, Abdominal; Apoptosis; Cardiac Pacing, Artificial; Constric | 1998 |
Positive inotropy due to lowering cyclic GMP is also mediated by increases in cyclic AMP in control and hypertrophic hearts.
Topics: Animals; Cardiotonic Agents; Cyclic AMP; Cyclic GMP; Dogs; Enzyme Inhibitors; Guanylate Cyclase; Hea | 1998 |
Effects of captopril treatment of renovascular hypertension on beta-adrenergic modulation of L-type Ca(2+) current.
Topics: Animals; Calcium Channels; Captopril; Colforsin; Dose-Response Relationship, Drug; Drug Interactions | 2000 |
Adenoviral gene transfer of SERCA2a improves left-ventricular function in aortic-banded rats in transition to heart failure.
Topics: Adenoviridae; Adrenergic beta-Agonists; Animals; Aorta; beta-Galactosidase; Calcium; Calcium-Transpo | 2000 |
Altered phosphorylation of sarcoplasmic reticulum contributes to the diminished contractile response to isoproterenol in hypertrophied rat hearts.
Topics: Animals; Blotting, Western; Calcium; Cardiomegaly; Cardiotonic Agents; Electrophoresis, Polyacrylami | 1999 |
Beta-adrenergic receptor density and function in left ventricular hypertrophy in young essential hypertensives.
Topics: Adrenergic beta-Agonists; Adult; Blood Pressure; Catecholamines; Cyclic AMP; Echocardiography; Femal | 2000 |
Effects of beta-adrenoceptor stimulation on pacing-induced failure of dog hypertrophic hearts.
Topics: Adrenergic beta-Agonists; Animals; Aortic Valve Stenosis; Blood Pressure; Body Weight; Cardiac Pacin | 2000 |
Down regulation of myocardial beta1-adrenoceptor signal transduction system in pacing-induced failure in dogs with aortic stenosis-induced left ventricular hypertrophy.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Adrenergic beta-Agonists; Analysis of Varian | 2000 |
[A comparative study of cardiac function in transgenic hypertensive rats, in spontaneously hypertensive rats and in normotensive rats].
Topics: Adrenergic beta-Agonists; Angiotensinogen; Animals; Animals, Genetically Modified; Atrial Natriureti | 2000 |
Altered beta-adrenergic signal transduction in nonfailing hypertrophied myocytes from Dahl salt-sensitive rats.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Calcium; Calcium Chan | 2000 |
Differential alterations in cardiac adrenergic signaling in chronic hypoxia or norepinephrine infusion.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cholera Toxin; Chroni | 2001 |
Reduction in myocardial collagen cross-linking parallels left ventricular dilatation in rat models of systolic chamber dysfunction.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Abdominal; Body Weight; Captopril; Collage | 2001 |
Myocardial adrenergic dysfunction in rats with transgenic, human renin-dependent hypertension.
Topics: Adrenergic beta-Agonists; Angiotensinogen; Animals; Animals, Genetically Modified; Blood Pressure; C | 2001 |
The action of isoprenaline on the electrophysiological properties of hypertrophied left ventricular myocytes.
Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Anti-Arrhythmia Agents; Calcium Channels, L-Ty | 2001 |
Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Caveolin 3; Caveolins; Heart; Hypertrophy, Left Ventricu | 2002 |