isoproterenol has been researched along with Interstitial Cell Tumor in 8 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Loss of gonadotropin receptors in murine Leydig tumor cells and of beta-adrenergic receptors in rat glioma C6 cells occurred following exposure of the cells to human chorionic gonadotropin and isoproterenol, respectively." | 3.67 | Down-regulation of gonadotropin and beta-adrenergic receptors by hormones and cyclic AMP. ( Fishman, PH; Rebois, RV; Zaremba, T, 1985) |
| "The AC of the Leydig cell tumors exhibited a much greater response to PGE1 than the AC in normal interstitial tissue (5-fold and 2-fold stimulation, respectively)." | 1.27 | A transplantable rat Leydig cell tumor--2. Adenylyl cyclase activation by prostaglandin E1, isoproterenol and glucagon. ( Attramadal, H; Erichsen, A; Hansson, V; Jahnsen, T, 1984) |
| "hCG, isoproterenol and PGE1 were able to stimulate testosterone production in vitro." | 1.27 | A transplantable rat Leydig cell tumor--5. Cellular localization of beta-adrenergic and prostaglandin receptors and their effects on testosterone production. ( Erichsen, A; Golf, S; Hansson, V; Levy, FO, 1988) |
| "In conclusion, cAMP production in Leydig cell tumors is stimulated by both PGE1 and isoproterenol." | 1.27 | A transplantable rat Leydig cell tumor--3. Isoproterenol and prostaglandin E1 (PGE1) responsive adenylyl cyclase (AC). Regulatory effects of nucleotides and magnesium. ( Attramadal, H; Erichsen, AA; Hansson, V; Jahnsen, T, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dix, CJ | 1 |
| Habberfield, AD | 1 |
| Cooke, BA | 1 |
| Erichsen, A | 2 |
| Jahnsen, T | 2 |
| Attramadal, H | 2 |
| Hansson, V | 3 |
| Hafez, MM | 1 |
| Ascoli, M | 2 |
| Pereira, ME | 1 |
| Segaloff, DL | 1 |
| Levy, FO | 1 |
| Golf, S | 1 |
| Fishman, PH | 2 |
| Rebois, RV | 2 |
| Zaremba, T | 1 |
| Erichsen, AA | 1 |
8 other studies available for isoproterenol and Interstitial Cell Tumor
| Article | Year |
|---|---|
Characterization of the homologous and heterologous desensitization of rat Leydig-tumour-cell adenylate cyclase.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Bucladesine; Centrifugation, Density Gradient; Cholera Toxi | 1984 |
A transplantable rat Leydig cell tumor--2. Adenylyl cyclase activation by prostaglandin E1, isoproterenol and glucagon.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Dose-Response Relationship, Drug; Enzyme Activation; Glucag | 1984 |
Epidermal growth factor desensitizes the gonadotropin-responsive adenylyl cyclase in membranes isolated from MA-10 Leydig tumor cells and luteinized rat ovaries.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cell Membrane; Cell-Free System; Chorionic Gonad | 1990 |
Inhibition of gonadotropin-responsive adenylate cyclase in MA-10 Leydig tumor cells by epidermal growth factor.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Chorionic Gona | 1988 |
A transplantable rat Leydig cell tumor--5. Cellular localization of beta-adrenergic and prostaglandin receptors and their effects on testosterone production.
Topics: Alprostadil; Animals; Chorionic Gonadotropin; Dinoprostone; Iodocyanopindolol; Isoproterenol; Leydig | 1988 |
Down-regulation of gonadotropin and beta-adrenergic receptors by hormones and cyclic AMP.
Topics: Animals; Bucladesine; Cell Line; Cholera Toxin; Chorionic Gonadotropin; Cyclic AMP; Glioma; Isoprote | 1985 |
Gonadotropin-mediated desensitization in a murine Leydig tumor cell line does not alter the regulatory and catalytic components of adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Bucladesine; Cell Line; Cholera Toxin; Chorionic Gonadotropin; Cyclic AM | 1986 |
A transplantable rat Leydig cell tumor--3. Isoproterenol and prostaglandin E1 (PGE1) responsive adenylyl cyclase (AC). Regulatory effects of nucleotides and magnesium.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Alprostadil; Animals; Cell Line; Guanosine Triphosphate; | 1986 |