Page last updated: 2024-10-29

isoproterenol and Insulinoma

isoproterenol has been researched along with Insulinoma in 5 studies

Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.

Insulinoma: A benign tumor of the PANCREATIC BETA CELLS. Insulinoma secretes excess INSULIN resulting in HYPOGLYCEMIA.

Research Excerpts

ExcerptRelevanceReference
"Neuropeptide Y (NPY) has been shown to inhibit insulin secretion from the islets of Langerhans."5.30Inhibition of glucose stimulated insulin secretion by neuropeptide Y is mediated via the Y1 receptor and inhibition of adenylyl cyclase in RIN 5AH rat insulinoma cells. ( Bloom, SR; Ghatei, MA; Hurley, JD; Karlsen, AE; Kulkarni, RN; Morgan, DG; Smith, DM; Wang, RM; Wang, ZL, 1998)
" Amylin significantly reduced insulin secretion in rat insulinoma cell lines (Rin m5F cells) that were stimulated by either isoproterenol and forskolin, but it did not affect insulin secretion stimulated by isobutyl-methylxanthine (IBMX) or dibutyryl cyclic-adenosine monophosphate (db-cAMP)."3.68The effects of amylin on insulin secretion from Rin m5F cells and glycogen synthesis and lipogenesis in rat primary cultured hepatocytes. ( Abe, S; Ishizuka, J; Murakami, M; Satoh, Y; Shintani, S; Suzuki, K; Suzuki, S; Thompson, JC; Toyota, T, 1992)
"The response of insulinoma tissue to glucose, alpha-ketoisocaproate, and the modifiers of insulin release, tolbutamide, isoproterenol, and acetylcholine, was studied."3.67Pharmacological modifications of insulin release in vitro from fuel-responsive transplantable insulinomas. ( Ferguson, DC; Hoenig, M; Matschinsky, FM, 1984)
"Neuropeptide Y (NPY) has been shown to inhibit insulin secretion from the islets of Langerhans."1.30Inhibition of glucose stimulated insulin secretion by neuropeptide Y is mediated via the Y1 receptor and inhibition of adenylyl cyclase in RIN 5AH rat insulinoma cells. ( Bloom, SR; Ghatei, MA; Hurley, JD; Karlsen, AE; Kulkarni, RN; Morgan, DG; Smith, DM; Wang, RM; Wang, ZL, 1998)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's3 (60.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hoenig, M1
Ferguson, DC1
Matschinsky, FM1
Vea, H1
Trovik, TS1
Sager, G1
Birkeland, K1
Revhaug, A1
Sundsfjord, J1
Jorde, R1
Morgan, DG1
Kulkarni, RN1
Hurley, JD1
Wang, ZL1
Wang, RM1
Ghatei, MA1
Karlsen, AE1
Bloom, SR1
Smith, DM1
Suzuki, S1
Murakami, M1
Abe, S1
Satoh, Y1
Shintani, S1
Ishizuka, J1
Suzuki, K1
Thompson, JC1
Toyota, T1
Pasmantier, R1
Danoff, A1
Fleischer, N1
Schubart, UK1

Other Studies

5 other studies available for isoproterenol and Insulinoma

ArticleYear
Pharmacological modifications of insulin release in vitro from fuel-responsive transplantable insulinomas.
    Endocrinology, 1984, Volume: 115, Issue:4

    Topics: Acetylcholine; Adenoma, Islet Cell; Animals; Blood Glucose; Glucagon; Glucose; Insulin; Insulinoma;

1984
Return of beta-adrenergic sensitivity in a patient with insulinoma after removal of the tumour.
    Diabetic medicine : a journal of the British Diabetic Association, 1997, Volume: 14, Issue:11

    Topics: Adrenergic beta-Agonists; Adult; Blood Glucose; Epinephrine; Glucagon; Human Growth Hormone; Humans;

1997
Inhibition of glucose stimulated insulin secretion by neuropeptide Y is mediated via the Y1 receptor and inhibition of adenylyl cyclase in RIN 5AH rat insulinoma cells.
    Diabetologia, 1998, Volume: 41, Issue:12

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Blotting, Northern; Cyclic AMP; Glucagon; G

1998
The effects of amylin on insulin secretion from Rin m5F cells and glycogen synthesis and lipogenesis in rat primary cultured hepatocytes.
    Diabetes research and clinical practice, 1992, Volume: 15, Issue:1

    Topics: Acetates; Amyloid; Animals; Arginine; Blood Glucose; Cell Line; Cells, Cultured; Colforsin; Cyclic A

1992
P19, a hormonally regulated phosphoprotein of peptide hormone-producing cells: secretagogue-induced phosphorylation in AtT-20 mouse pituitary tumor cells and in rat and hamster insulinoma cells.
    Endocrinology, 1986, Volume: 119, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenoma, Islet Cell; Adrenocort

1986