isoproterenol has been researched along with Insulin Sensitivity in 65 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We measured in vivo their metabolic parameters, fasting glucose level, area under the curve (AUC) for glucose level time profile, insulin level time profile, insulin sensitivity index, and chromium distribution." | 7.85 | Isoproterenol exacerbates hyperglycemia and modulates chromium distribution in mice fed with a high fat diet. ( Chang, GR; Chen, WK; Hou, PH; Mao, FC, 2017) |
| " This work investigated the protective effect of pioglitazone on myocardial infarction (MI) in non-diabetic and diabetic rats, focusing on its role on advanced glycated endproducts (AGEs) and cardiac apoptotic machinery." | 7.83 | Cardioprotective effect of pioglitazone in diabetic and non-diabetic rats subjected to acute myocardial infarction involves suppression of AGE-RAGE axis and inhibition of apoptosis. ( Farag, NE; Khodeer, DM; Moustafa, YM; Zaitone, SA, 2016) |
| "We have previously shown that pentoxifylline (PTX) protects from vascular complications associated with insulin resistance (IR)." | 7.80 | Pentoxifylline alleviates cardiac ischemia and dysfunction following experimental angina in insulin resistance. ( Azhar, A; El-Bassossy, HM, 2014) |
| "Insulin resistance was induced by HFrHFD feeding for 16 weeks." | 5.62 | Propranolol and low-dose isoproterenol ameliorate insulin resistance, enhance β-arrestin2 signaling, and reduce cardiac remodeling in high-fructose, high-fat diet-fed mice: Comparative study with metformin. ( Ahmed, HMS; Ibrahim, IAAE; Ibrahim, WS; Mahmoud, AAA; Mahmoud, MF, 2021) |
| " We measured in vivo their metabolic parameters, fasting glucose level, area under the curve (AUC) for glucose level time profile, insulin level time profile, insulin sensitivity index, and chromium distribution." | 3.85 | Isoproterenol exacerbates hyperglycemia and modulates chromium distribution in mice fed with a high fat diet. ( Chang, GR; Chen, WK; Hou, PH; Mao, FC, 2017) |
| "Beta-adrenergic receptor agonist, isoproterenol, and an adenylate cyclase activator, forskolin, at a single dose significantly reduced insulin resistance consistent with a decrease in total and phospho-p53 levels in insulin and non-insulin metabolic target tissues." | 3.83 | Obesity-induced p53 activation in insulin-dependent and independent tissues is inhibited by beta-adrenergic agonist in diet-induced obese rats. ( Cheraghpour, M; Ghorbani, A; Homayounfar, R; Jeddi-Tehrani, M; Pourvali, K; Soltani, SR; Zand, H, 2016) |
| " This work investigated the protective effect of pioglitazone on myocardial infarction (MI) in non-diabetic and diabetic rats, focusing on its role on advanced glycated endproducts (AGEs) and cardiac apoptotic machinery." | 3.83 | Cardioprotective effect of pioglitazone in diabetic and non-diabetic rats subjected to acute myocardial infarction involves suppression of AGE-RAGE axis and inhibition of apoptosis. ( Farag, NE; Khodeer, DM; Moustafa, YM; Zaitone, SA, 2016) |
| "We have previously shown that pentoxifylline (PTX) protects from vascular complications associated with insulin resistance (IR)." | 3.80 | Pentoxifylline alleviates cardiac ischemia and dysfunction following experimental angina in insulin resistance. ( Azhar, A; El-Bassossy, HM, 2014) |
| "Curcumin, an active component derived from dietary spice turmeric (Curcuma longa), has been demonstrated antihyperglycemic, antiinflammatory and hypocholesterolemic activities in obesity and diabetes." | 3.78 | Curcumin attenuates lipolysis stimulated by tumor necrosis factor-α or isoproterenol in 3T3-L1 adipocytes. ( Kong, PR; Li, Y; Li, YX; Wu, JF; Xie, XY, 2012) |
| "The intake of a high-fat diet by rats induced a significant increase in body weight, adiposity and insulin resistance markers as well as a decrease in faecal corticosterone levels compared with standard diet-fed rats." | 3.75 | Ascorbic acid oral treatment modifies lipolytic response and behavioural activity but not glucocorticoid metabolism in cafeteria diet-fed rats. ( Campion, J; Garcia-Diaz, DF; Martinez, JA; Milagro, FI; Paternain, L; Solomon, A, 2009) |
| " Insulin resistance was induced by treating cardiac myocytes with isoproterenol, a beta-adrenergic receptor agonist." | 3.74 | Insulin resistance affects the cytoprotective effect of insulin in cardiomyocytes through an impairment of MAPK phosphatase-1 expression. ( Crispo, S; Marrone, C; Monti, MG; Morisco, C; Sadoshima, J; Trimarco, B; Trimarco, V, 2007) |
| " Administration of the beta-adrenergic agonist isoproterenol during the period of insulin resistance (days 26-40 after primary immunization), largely restored fat cell responsiveness to insulin, and eliminated the appearance of fasting hyperglycemia." | 3.67 | Desensitization of the insulin receptor by antireceptor antibodies in vivo is blocked by treatment of mice with beta-adrenergic agonists. ( Cohen, IR; Elias, D; Rapoport, M; Shechter, Y, 1988) |
| "To analyze B-cell mechanisms in obesity, we measured the relationship (slope of potentiation) between glucose levels and acute insulin responses (AIR) to isoproterenol or arginine in nondiabetic subjects ranging from lean to markedly obese." | 3.67 | Relationship of islet function to insulin action in human obesity. ( Beard, JC; Halter, JB; Porte, D; Wallum, BJ; Ward, WK, 1987) |
| "The isoproterenol-induced increase in EGC was higher after the training." | 2.71 | Dynamic strength training improves insulin sensitivity and functional balance between adrenergic alpha 2A and beta pathways in subcutaneous adipose tissue of obese subjects. ( Berlan, M; Hejnova, J; Klimcakova, E; Lafontan, M; Langin, D; Majercik, M; Moro, C; Polak, J; Stich, V; Viguerie, N, 2005) |
| "Insulin resistance was induced by HFrHFD feeding for 16 weeks." | 1.62 | Propranolol and low-dose isoproterenol ameliorate insulin resistance, enhance β-arrestin2 signaling, and reduce cardiac remodeling in high-fructose, high-fat diet-fed mice: Comparative study with metformin. ( Ahmed, HMS; Ibrahim, IAAE; Ibrahim, WS; Mahmoud, AAA; Mahmoud, MF, 2021) |
| "Insulin resistance is a condition in which cells are defective in response to the actions of insulin in tissue glucose uptake." | 1.43 | Sustained βAR Stimulation Mediates Cardiac Insulin Resistance in a PKA-Dependent Manner. ( Denkaew, T; Mangmool, S; Nishida, M; Parichatikanond, W; Phosri, S; Pinthong, D; Shimauchi, T, 2016) |
| " Dose-response curves were created between the concentration of isoproterenol or insulin and the amount of glycerol released." | 1.43 | Influence of adipocyte size and adipose depot on the in vitro lipolytic activity and insulin sensitivity of adipose tissue in dairy cows at the end of the dry period. ( Claeys, E; De Koster, J; Fievez, V; Hermans, K; Hostens, M; Hulpio, L; Opsomer, G; Van den Broeck, W; Van Eetvelde, M, 2016) |
| "Insulin resistance is a powerful predictor of cardiovascular disease; however, the mechanistic link remains unclear." | 1.43 | Pressor recovery after acute stress is impaired in high fructose-fed Lean Zucker rats. ( D'Angelo, G; Fulton, DJ; Mintz, JD; Stepp, DW; Thompson, JA, 2016) |
| "Obesity increases preeclampsia risk, and maternal dyslipidemia may result from exaggerated adipocyte lipolysis." | 1.40 | In preeclampsia, maternal third trimester subcutaneous adipocyte lipolysis is more resistant to suppression by insulin than in healthy pregnancy. ( Forrest, R; Freeman, DJ; Huda, SS; Jordan, F; Paterson, N; Sattar, N, 2014) |
| "One of the common complications of type 2 diabetes mellitus (DM2) are cardiovascular diseases and dysfunctions of the reproductive system, indicating the urgency of developing new approaches to their correction." | 1.40 | [The influence of two-month treatment with bromocryptine on activity of the adenylyl cyclase signaling system in the myocardium and testes of rats with type 2 diabetes mellitus]. ( Bondareva, VM; Derkach, KV; Moyseyuk, IV; Shpakov, AO, 2014) |
| "Insulin sensitivity was determined (hyperinsulinaemic euglycaemic clamp) prior to and 72 h following each intervention." | 1.36 | Short-term sprint interval training increases insulin sensitivity in healthy adults but does not affect the thermogenic response to beta-adrenergic stimulation. ( Bell, C; Johnson, TK; Kuzma, JN; Lonac, MC; Richards, JC; Schweder, MM; Voyles, WF, 2010) |
| " The dose-response relationship between insulin and inhibition of ISO-stimulated lipolysis showed that insulin sensitivity was increased and responsiveness unaltered in S and D compared to C adipocytes for incubations with both uncontrolled and controlled adenosine concentrations." | 1.28 | Antilipolytic action of insulin in adipocytes from starved and diabetic rats during adenosine-controlled incubations. ( Bosman, J; Koopmans, SJ; Krans, HM; Radder, JK; Sips, HC, 1989) |
| " This change occurs in parallel with a moderate rightward shift in the insulin dose-response curve." | 1.27 | Isoproterenol reduces insulin stimulation of hexose uptake by rat adipocytes via a postinsulin binding alteration. ( Arsenis, G; Livingston, JN, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (21.54) | 18.7374 |
| 1990's | 8 (12.31) | 18.2507 |
| 2000's | 16 (24.62) | 29.6817 |
| 2010's | 24 (36.92) | 24.3611 |
| 2020's | 3 (4.62) | 2.80 |
| Authors | Studies |
|---|---|
| Ibrahim, WS | 1 |
| Ahmed, HMS | 1 |
| Mahmoud, AAA | 1 |
| Mahmoud, MF | 1 |
| Ibrahim, IAAE | 1 |
| Du, X | 1 |
| Liu, M | 1 |
| Tai, W | 1 |
| Yu, H | 1 |
| Hao, X | 1 |
| Loor, JJ | 1 |
| Jiang, Q | 1 |
| Fang, Z | 1 |
| Gao, X | 1 |
| Fan, M | 1 |
| Gao, W | 1 |
| Lei, L | 1 |
| Song, Y | 1 |
| Wang, Z | 1 |
| Zhang, C | 1 |
| Liu, G | 1 |
| Li, X | 1 |
| Trinh, MD | 1 |
| Plihalova, A | 1 |
| Gojda, J | 1 |
| Westlake, K | 1 |
| Spicka, J | 1 |
| Lattova, Z | 1 |
| Pretl, M | 1 |
| Polak, J | 2 |
| Chang, GR | 1 |
| Chen, WK | 1 |
| Hou, PH | 1 |
| Mao, FC | 1 |
| Chechi, K | 1 |
| Voisine, P | 1 |
| Mathieu, P | 1 |
| Laplante, M | 1 |
| Bonnet, S | 1 |
| Picard, F | 1 |
| Joubert, P | 1 |
| Richard, D | 1 |
| Geng, B | 1 |
| Cai, B | 1 |
| Liao, F | 1 |
| Zheng, Y | 1 |
| Zeng, Q | 1 |
| Fan, X | 1 |
| Gong, Y | 1 |
| Yang, J | 1 |
| Cui, QH | 1 |
| Tang, C | 1 |
| Xu, GH | 1 |
| Huda, SS | 1 |
| Forrest, R | 1 |
| Paterson, N | 1 |
| Jordan, F | 1 |
| Sattar, N | 1 |
| Freeman, DJ | 1 |
| Higa, TS | 1 |
| Spinola, AV | 1 |
| Fonseca-Alaniz, MH | 1 |
| Evangelista, FS | 1 |
| Azhar, A | 1 |
| El-Bassossy, HM | 2 |
| Furuhashi, M | 1 |
| Mita, T | 1 |
| Moniwa, N | 1 |
| Hoshina, K | 1 |
| Ishimura, S | 1 |
| Fuseya, T | 1 |
| Watanabe, Y | 1 |
| Yoshida, H | 1 |
| Shimamoto, K | 1 |
| Miura, T | 1 |
| Watson, ML | 1 |
| Derkach, KV | 1 |
| Bondareva, VM | 1 |
| Moyseyuk, IV | 1 |
| Shpakov, AO | 1 |
| Mangmool, S | 1 |
| Denkaew, T | 1 |
| Phosri, S | 1 |
| Pinthong, D | 1 |
| Parichatikanond, W | 1 |
| Shimauchi, T | 1 |
| Nishida, M | 1 |
| De Koster, J | 1 |
| Van den Broeck, W | 1 |
| Hulpio, L | 1 |
| Claeys, E | 1 |
| Van Eetvelde, M | 1 |
| Hermans, K | 1 |
| Hostens, M | 1 |
| Fievez, V | 1 |
| Opsomer, G | 1 |
| Zand, H | 1 |
| Homayounfar, R | 1 |
| Cheraghpour, M | 1 |
| Jeddi-Tehrani, M | 1 |
| Ghorbani, A | 1 |
| Pourvali, K | 1 |
| Soltani, SR | 1 |
| Khodeer, DM | 1 |
| Zaitone, SA | 1 |
| Farag, NE | 1 |
| Moustafa, YM | 1 |
| Thompson, JA | 1 |
| D'Angelo, G | 1 |
| Mintz, JD | 1 |
| Fulton, DJ | 1 |
| Stepp, DW | 1 |
| Guénantin, AC | 1 |
| Briand, N | 1 |
| Capel, E | 1 |
| Dumont, F | 1 |
| Morichon, R | 1 |
| Provost, C | 1 |
| Stillitano, F | 1 |
| Jeziorowska, D | 1 |
| Siffroi, JP | 1 |
| Hajjar, RJ | 1 |
| Fève, B | 1 |
| Hulot, JS | 1 |
| Collas, P | 1 |
| Capeau, J | 1 |
| Vigouroux, C | 1 |
| Garcia-Diaz, DF | 1 |
| Campion, J | 1 |
| Milagro, FI | 1 |
| Paternain, L | 1 |
| Solomon, A | 1 |
| Martinez, JA | 1 |
| Lessard, SJ | 1 |
| Rivas, DA | 1 |
| Chen, ZP | 1 |
| van Denderen, BJ | 1 |
| Watt, MJ | 1 |
| Koch, LG | 1 |
| Britton, SL | 1 |
| Kemp, BE | 1 |
| Hawley, JA | 1 |
| Fried, SK | 2 |
| Tittelbach, T | 1 |
| Blumenthal, J | 1 |
| Sreenivasan, U | 1 |
| Robey, L | 1 |
| Yi, J | 1 |
| Khan, S | 1 |
| Hollender, C | 1 |
| Ryan, AS | 1 |
| Goldberg, AP | 1 |
| Selenscig, D | 1 |
| Rossi, A | 1 |
| Chicco, A | 1 |
| Lombardo, YB | 1 |
| Teixeira, D | 1 |
| Pestana, D | 1 |
| Faria, A | 1 |
| Calhau, C | 1 |
| Azevedo, I | 1 |
| Monteiro, R | 1 |
| Richards, JC | 1 |
| Johnson, TK | 1 |
| Kuzma, JN | 1 |
| Lonac, MC | 1 |
| Schweder, MM | 1 |
| Voyles, WF | 1 |
| Bell, C | 1 |
| Muscogiuri, G | 1 |
| Kamat, A | 1 |
| Balas, B | 1 |
| Giaccari, A | 1 |
| Defronzo, RA | 1 |
| Musi, N | 1 |
| Katz, MS | 1 |
| Goossens, GH | 1 |
| Bizzarri, A | 1 |
| Venteclef, N | 1 |
| Essers, Y | 1 |
| Cleutjens, JP | 1 |
| Konings, E | 1 |
| Jocken, JW | 1 |
| Cajlakovic, M | 1 |
| Ribitsch, V | 1 |
| Clément, K | 1 |
| Blaak, EE | 1 |
| Oliver, P | 1 |
| Caimari, A | 1 |
| Díaz-Rúa, R | 1 |
| Palou, A | 1 |
| Shimizu, I | 1 |
| Yoshida, Y | 1 |
| Katsuno, T | 1 |
| Tateno, K | 1 |
| Okada, S | 1 |
| Moriya, J | 1 |
| Yokoyama, M | 1 |
| Nojima, A | 1 |
| Ito, T | 1 |
| Zechner, R | 1 |
| Komuro, I | 1 |
| Kobayashi, Y | 1 |
| Minamino, T | 1 |
| Xie, XY | 1 |
| Kong, PR | 1 |
| Wu, JF | 1 |
| Li, Y | 1 |
| Li, YX | 1 |
| Fasshauer, M | 3 |
| Klein, J | 3 |
| Lossner, U | 3 |
| Paschke, R | 3 |
| Valensi, P | 1 |
| Doaré, L | 1 |
| Perret, G | 1 |
| Germack, R | 1 |
| Pariès, J | 1 |
| Mesangeau, D | 1 |
| Morisco, C | 2 |
| Condorelli, G | 2 |
| Trimarco, V | 2 |
| Bellis, A | 1 |
| Marrone, C | 2 |
| Sadoshima, J | 2 |
| Trimarco, B | 2 |
| Tian, R | 1 |
| Boiko, J | 1 |
| Jaquet, D | 1 |
| Chevenne, D | 1 |
| Rigal, O | 1 |
| Czernichow, P | 1 |
| Lévy-Marchal, C | 1 |
| Moro, C | 1 |
| Klimcakova, E | 1 |
| Hejnova, J | 1 |
| Majercik, M | 1 |
| Viguerie, N | 1 |
| Langin, D | 2 |
| Lafontan, M | 1 |
| Stich, V | 1 |
| Berlan, M | 1 |
| Leibel, RL | 1 |
| Edens, NK | 1 |
| Kral, JG | 1 |
| Crispo, S | 1 |
| Monti, MG | 1 |
| Kirsch, DM | 2 |
| Bachmann, W | 1 |
| Häring, HU | 3 |
| Beard, JC | 2 |
| Halter, JB | 2 |
| Best, JD | 1 |
| Pfeifer, MA | 1 |
| Porte, D | 2 |
| Baumgarten, M | 1 |
| Deufel, T | 1 |
| Rinninger, F | 1 |
| Kemmler, W | 1 |
| Reynisdottir, S | 2 |
| Ellerfeldt, K | 1 |
| Wahrenberg, H | 1 |
| Lithell, H | 1 |
| Arner, P | 2 |
| Hellström, L | 1 |
| Rössner, S | 1 |
| Ciaraldi, TP | 1 |
| Morales, AJ | 1 |
| Hickman, MG | 1 |
| Odom-Ford, R | 1 |
| Olefsky, JM | 1 |
| Yen, SS | 1 |
| Stenbit, AE | 1 |
| Tsao, TS | 1 |
| Li, J | 1 |
| Burcelin, R | 1 |
| Geenen, DL | 1 |
| Factor, SM | 1 |
| Houseknecht, K | 1 |
| Katz, EB | 1 |
| Charron, MJ | 1 |
| Abbasi, F | 1 |
| McLaughlin, T | 1 |
| Lamendola, C | 1 |
| Reaven, GM | 1 |
| Ohkura, K | 1 |
| Hori, H | 1 |
| Kawabe, J | 1 |
| Aizawa, Y | 1 |
| Takehara, N | 1 |
| Hasebe, N | 1 |
| Kikuchi, K | 1 |
| Walsh, MF | 1 |
| Ali, SS | 1 |
| Sowers, JR | 1 |
| Monzon, JR | 1 |
| Basile, R | 1 |
| Heneghan, S | 1 |
| Udupi, V | 1 |
| Green, A | 1 |
| García-Sáinz, JA | 1 |
| Alcántara-Hernández, R | 1 |
| Robles-Flores, M | 1 |
| Torres-Márquez, ME | 1 |
| Massillon, D | 1 |
| Annabi, B | 1 |
| Van de Werve, G | 1 |
| Eckel, J | 2 |
| Asskamp, B | 1 |
| Reinauer, H | 2 |
| Petersen, S | 1 |
| Russ, M | 1 |
| Koopmans, SJ | 1 |
| Sips, HC | 1 |
| Bosman, J | 1 |
| Radder, JK | 1 |
| Krans, HM | 1 |
| Arsenis, G | 1 |
| Livingston, JN | 1 |
| Obermaier, B | 2 |
| Ermel, B | 2 |
| Kirsch, D | 2 |
| Mushack, J | 1 |
| Rattenhuber, E | 1 |
| Biemer, E | 1 |
| Machicao, F | 2 |
| Elias, D | 1 |
| Rapoport, M | 1 |
| Cohen, IR | 1 |
| Shechter, Y | 1 |
| Ward, WK | 1 |
| Wallum, BJ | 1 |
| Panacek, EA | 1 |
| Sherman, B | 1 |
| Häring, H | 1 |
| Simpson, IB | 1 |
| Karnieli, E | 1 |
| Hissin, PJ | 1 |
| Smith, U | 1 |
| Cushman, SW | 1 |
| Kahn, CR | 1 |
| Neville, DM | 1 |
| Roth, J | 1 |
| Bégin-Heck, N | 1 |
| Bourassa, M | 1 |
| Heick, HM | 1 |
| Abramson, EA | 1 |
| Arky, RA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Allopurinol in the Treatment of Patients With Diabetes Mellitus and Multivessel Coronary Artery Disease Treated by Either PCI or CABG: Pilot Study[NCT03700645] | Phase 4 | 100 participants (Anticipated) | Interventional | 2018-12-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for isoproterenol and Insulin Sensitivity
| Article | Year |
|---|---|
In situ lipolytic regulation in subjects born small for gestational age.
Topics: Abdomen; Adipose Tissue; Adrenergic beta-Agonists; Adult; Case-Control Studies; Chi-Square Distribut | 2005 |
Dynamic strength training improves insulin sensitivity and functional balance between adrenergic alpha 2A and beta pathways in subcutaneous adipose tissue of obese subjects.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Recept | 2005 |
Insulin regulation of plasma free fatty acid concentrations is abnormal in healthy subjects with muscle insulin resistance.
Topics: Adrenergic beta-Agonists; Blood Pressure; Fatty Acids, Nonesterified; Female; Humans; Insulin; Insul | 2000 |
62 other studies available for isoproterenol and Insulin Sensitivity
| Article | Year |
|---|---|
Propranolol and low-dose isoproterenol ameliorate insulin resistance, enhance β-arrestin2 signaling, and reduce cardiac remodeling in high-fructose, high-fat diet-fed mice: Comparative study with metformin.
Topics: Animals; beta-Arrestin 2; Blood Glucose; Diet, High-Fat; Fructose; Glucose; Heart; Insulin; Insulin | 2021 |
Tumor necrosis factor-α promotes lipolysis and reduces insulin sensitivity by activating nuclear factor kappa B and c-Jun N-terminal kinase in primary bovine adipocytes.
Topics: Adipocytes; Animals; Caspase 3; Cattle; Cattle Diseases; Female; Glycerol; Insulin Resistance; Insul | 2022 |
Obstructive sleep apnoea increases lipolysis and deteriorates glucose homeostasis in patients with type 2 diabetes mellitus.
Topics: Adipose Tissue; Aged; Diabetes Mellitus, Type 2; Epinephrine; Female; Glucose; Homeostasis; Humans; | 2021 |
Isoproterenol exacerbates hyperglycemia and modulates chromium distribution in mice fed with a high fat diet.
Topics: Animals; Blood Glucose; Body Weight; Chromium; Creatinine; Diet, High-Fat; Disease Progression; Ener | 2017 |
Functional characterization of the Ucp1-associated oxidative phenotype of human epicardial adipose tissue.
Topics: Adipocytes, Brown; Adipose Tissue; Adipose Tissue, Brown; Aged; Biopsy; Body Mass Index; Female; Gen | 2017 |
Increase or decrease hydrogen sulfide exert opposite lipolysis, but reduce global insulin resistance in high fatty diet induced obese mice.
Topics: Adipocytes; Alkynes; Animals; Blood Glucose; Carrier Proteins; Cystathionine gamma-Lyase; Cysteine; | 2013 |
In preeclampsia, maternal third trimester subcutaneous adipocyte lipolysis is more resistant to suppression by insulin than in healthy pregnancy.
Topics: Adipocytes; Adult; Biopsy; Case-Control Studies; Female; Humans; Insulin; Insulin Resistance; Intra- | 2014 |
Remodeling of white adipose tissue metabolism by physical training prevents insulin resistance.
Topics: Adipocytes; Adiponectin; Adipose Tissue, White; Adiposity; Animals; Fatty Acids, Nonesterified; Gluc | 2014 |
Pentoxifylline alleviates cardiac ischemia and dysfunction following experimental angina in insulin resistance.
Topics: Adiponectin; Administration, Oral; Angina Pectoris; Animals; Diet; Disease Models, Animal; Electroca | 2014 |
Angiotensin II receptor blockers decrease serum concentration of fatty acid-binding protein 4 in patients with hypertension.
Topics: 3T3 Cells; Adrenergic beta-Agonists; Amlodipine; Angiotensin II Type 2 Receptor Blockers; Animals; A | 2015 |
Xanthine oxidase inhibition alleviates the cardiac complications of insulin resistance: effect on low grade inflammation and the angiotensin system.
Topics: Administration, Oral; Allopurinol; Angiotensin II; Animals; Diet, High-Fat; Electrocardiography; Enz | 2015 |
[The influence of two-month treatment with bromocryptine on activity of the adenylyl cyclase signaling system in the myocardium and testes of rats with type 2 diabetes mellitus].
Topics: Adenylyl Cyclases; Administration, Oral; Animals; Blood Glucose; Bromocriptine; Diabetes Mellitus, E | 2014 |
Sustained βAR Stimulation Mediates Cardiac Insulin Resistance in a PKA-Dependent Manner.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cyclic AMP-Dependent Protein Kinases | 2016 |
Influence of adipocyte size and adipose depot on the in vitro lipolytic activity and insulin sensitivity of adipose tissue in dairy cows at the end of the dry period.
Topics: Adipocytes; Adipose Tissue; Adrenergic beta-Agonists; Animals; Body Composition; Cattle; Cells, Cult | 2016 |
Obesity-induced p53 activation in insulin-dependent and independent tissues is inhibited by beta-adrenergic agonist in diet-induced obese rats.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Blotting, Western; Colforsin; Cyclic AMP; Insu | 2016 |
Cardioprotective effect of pioglitazone in diabetic and non-diabetic rats subjected to acute myocardial infarction involves suppression of AGE-RAGE axis and inhibition of apoptosis.
Topics: Adrenergic beta-Agonists; Animals; Apoptosis; Cardiotonic Agents; Diabetes Mellitus, Type 2; Diabeti | 2016 |
Pressor recovery after acute stress is impaired in high fructose-fed Lean Zucker rats.
Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Dietary Carbohydrates; Fructose; Hindlimb; Insuli | 2016 |
Functional Human Beige Adipocytes From Induced Pluripotent Stem Cells.
Topics: Adipocytes, Beige; Adipogenesis; Adipose Tissue; Adrenergic beta-Agonists; Animals; Cell Transplanta | 2017 |
Ascorbic acid oral treatment modifies lipolytic response and behavioural activity but not glucocorticoid metabolism in cafeteria diet-fed rats.
Topics: Adipocytes; Adiposity; Administration, Oral; Animals; Antioxidants; Ascorbic Acid; Biomarkers; Body | 2009 |
Impaired skeletal muscle beta-adrenergic activation and lipolysis are associated with whole-body insulin resistance in rats bred for low intrinsic exercise capacity.
Topics: Adrenergic beta-Agonists; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Exercise; Gene | 2009 |
Resistance to the antilipolytic effect of insulin in adipocytes of African-American compared to Caucasian postmenopausal women.
Topics: Abdominal Fat; Adipocytes; Adult; Aged; Black or African American; Buttocks; Fatty Acids, Nonesterif | 2010 |
Increased leptin storage with altered leptin secretion from adipocytes of rats with sucrose-induced dyslipidemia and insulin resistance: effect of dietary fish oil.
Topics: Adipocytes; Adipose Tissue, White; Adrenergic beta-Agonists; Animals; Body Weight; Cell Count; Cell | 2010 |
Modulation of adipocyte biology by δ(9)-tetrahydrocannabinol.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Adiponectin; Animals; Cannabis; Dronabinol; Insulin; Insulin | 2010 |
Short-term sprint interval training increases insulin sensitivity in healthy adults but does not affect the thermogenic response to beta-adrenergic stimulation.
Topics: Adult; Body Temperature Regulation; Dose-Response Relationship, Drug; Exercise; Female; Humans; Insu | 2010 |
β-Adrenergic Responsive Induction of Insulin Resistance in Liver of Aging Rats.
Topics: Adrenergic beta-Agonists; Aging; Animals; Glucose; Insulin; Insulin Resistance; Insulin Secretion; I | 2011 |
Increased adipose tissue oxygen tension in obese compared with lean men is accompanied by insulin resistance, impaired adipose tissue capillarization, and inflammation.
Topics: Adipose Tissue; Angiotensin II; Humans; Hyperoxia; Inflammation; Insulin Resistance; Isoproterenol; | 2011 |
Cold exposure down-regulates adiponutrin/PNPLA3 mRNA expression and affects its nutritional regulation in adipose tissues of lean and obese Zucker rats.
Topics: Adipocytes; Adipose Tissue; Animal Nutrition Sciences; Animals; Blood Glucose; Body Weight; Cells, C | 2012 |
p53-induced adipose tissue inflammation is critically involved in the development of insulin resistance in heart failure.
Topics: Adipose Tissue; Animals; Cell Line; Heart Failure; Humans; Inflammation; Insulin Resistance; Isoprot | 2012 |
Curcumin attenuates lipolysis stimulated by tumor necrosis factor-α or isoproterenol in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Carrier Proteins; Curcuma; Curcumin; Diabetes Mellitus, Type 2; D | 2012 |
Negative regulation of adipose-expressed galectin-12 by isoproterenol, tumor necrosis factor alpha, insulin and dexamethasone.
Topics: Adenylyl Cyclases; Adipocytes; Adrenergic beta-Agonists; Animals; Antineoplastic Agents; Cell Cycle | 2002 |
Isoproterenol is a positive regulator of the suppressor of cytokine signaling-3 gene expression in 3T3-L1 adipocytes.
Topics: 3T3 Cells; Adenylyl Cyclases; Adipocytes; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Ani | 2002 |
Cardiovascular vagosympathetic activity in rats with ventromedial hypothalamic obesity.
Topics: Animals; Atropine; Blood Glucose; Blood Pressure; Body Weight; Cardiovascular System; Epinephrine; F | 2003 |
Interleukin (IL)-6 mRNA expression is stimulated by insulin, isoproterenol, tumour necrosis factor alpha, growth hormone, and IL-6 in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adenylyl Cyclases; Adipocytes; Adrenergic beta-Agonists; Animals; Bucladesine; Cholera | 2003 |
Akt mediates the cross-talk between beta-adrenergic and insulin receptors in neonatal cardiomyocytes.
Topics: Adrenergic beta-Agonists; Amino Acid Substitution; Animals; Animals, Newborn; Cells, Cultured; Cycli | 2005 |
Another role for the celebrity: Akt and insulin resistance.
Topics: Adrenergic beta-Agonists; Animals; Deoxyglucose; Enzyme Activation; Humans; Insulin Resistance; Isop | 2005 |
Lipolysis in intraabdominal adipose tissues of obese women and men.
Topics: Abdomen; Adipocytes; Adipose Tissue; Body Composition; Body Constitution; Body Mass Index; Body Weig | 1993 |
Insulin resistance affects the cytoprotective effect of insulin in cardiomyocytes through an impairment of MAPK phosphatase-1 expression.
Topics: Adrenergic beta-Agonists; Animals; Apoptosis; Caspase 3; Cell Hypoxia; Cells, Cultured; Dual Specifi | 2007 |
Ciglitazone reverses cAMP-induced post-insulin receptor resistance in rat adipocytes in vitro.
Topics: 3-O-Methylglucose; Adipose Tissue; Animals; Biological Transport; Cyclic AMP; Insulin; Insulin Resis | 1984 |
Dexamethasone-induced insulin resistance enhances B cell responsiveness to glucose level in normal men.
Topics: Adaptation, Physiological; Adult; Blood Glucose; Dexamethasone; Humans; Hyperglycemia; Hyperinsulini | 1984 |
Catecholamine-induced insulin resistance of glucose transport in isolated rat adipocytes.
Topics: Adenosine Triphosphate; Adipose Tissue; Animals; Biological Transport; Glucose; In Vitro Techniques; | 1983 |
Multiple lipolysis defects in the insulin resistance (metabolic) syndrome.
Topics: Adipose Tissue; Aged; Clonidine; Dose-Response Relationship, Drug; Humans; Insulin Resistance; Isopr | 1994 |
Regulation of lipolysis in fat cells of obese women during long-term hypocaloric diet.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adipocytes; Adrenergic beta-Agonists; Adult; Brimonidine Tar | 1996 |
Cellular insulin resistance in adipocytes from obese polycystic ovary syndrome subjects involves adenosine modulation of insulin sensitivity.
Topics: Adenosine; Adipocytes; Adrenergic beta-Agonists; Adult; Female; Follicle Stimulating Hormone; Glucos | 1997 |
GLUT4 heterozygous knockout mice develop muscle insulin resistance and diabetes.
Topics: Animals; Blood Glucose; Blood Pressure; Deoxyglucose; Diabetes Mellitus, Type 2; Glucose Transporter | 1997 |
Analyses of insulin-potentiating fragments of human growth hormone by computative simulation; essential unit for insulin-involved biological responses.
Topics: Adipocytes; Adipose Tissue; Animals; Computer Simulation; Dose-Response Relationship, Drug; Electrop | 2000 |
Glucose modifies the cross-talk between insulin and the beta-adrenergic signalling system in vascular smooth muscle cells.
Topics: Animals; Cells, Cultured; Chromans; Glucose; Insulin; Insulin Receptor Substrate Proteins; Insulin R | 2000 |
Vascular insulin/insulin-like growth factor-1 resistance in female obese Zucker rats.
Topics: Animals; Aorta; Cholera Toxin; Deoxyglucose; Drug Resistance; Endothelium, Vascular; Female; GTP-Bin | 2001 |
Lipolysis in adipocytes isolated from deep and superficial subcutaneous adipose tissue.
Topics: Adipocytes; Adipose Tissue; Adult; Aged; Blotting, Western; Collagenases; Female; Glycerol; Humans; | 2002 |
Modulation by protein kinase C of the hormonal responsiveness of hepatocytes from lean (Fa/fa?) and obese (fa/fa) Zucker rats.
Topics: Animals; Enzyme Activation; Insulin Resistance; Isoenzymes; Isoproterenol; Liver; Obesity; Phenyleph | 1992 |
Induction of insulin resistance in primary cultured adult cardiac myocytes.
Topics: Animals; Biological Transport; Bucladesine; Cells, Cultured; Cyclic AMP; Cycloheximide; Cytochalasin | 1991 |
Inverse regulation of glucose transporter Glut4 and G-protein Gs mRNA expression in cardiac myocytes from insulin resistant rats.
Topics: Animals; Blotting, Northern; Diabetes Mellitus, Experimental; GTP-Binding Proteins; Insulin Resistan | 1991 |
Antilipolytic action of insulin in adipocytes from starved and diabetic rats during adenosine-controlled incubations.
Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Animals; Diabetes Mellitus, Experimental; Insulin; I | 1989 |
Isoproterenol reduces insulin stimulation of hexose uptake by rat adipocytes via a postinsulin binding alteration.
Topics: Adipose Tissue; Animals; Biological Transport; Cyclic AMP; Deoxy Sugars; Deoxyglucose; Epididymis; H | 1986 |
Catecholamines and tumour promoting phorbolesters inhibit insulin receptor kinase and induce insulin resistance in isolated human adipocytes.
Topics: 3-O-Methylglucose; Adenosine Triphosphate; Adipose Tissue; Biological Transport; Humans; Insulin; In | 1987 |
Desensitization of the insulin receptor by antireceptor antibodies in vivo is blocked by treatment of mice with beta-adrenergic agonists.
Topics: Adipose Tissue; Aminophylline; Animals; Fasting; Hyperglycemia; Immunoglobulin Idiotypes; Insulin; I | 1988 |
Relationship of islet function to insulin action in human obesity.
Topics: Adult; Arginine; Blood Glucose; Female; Humans; Insulin; Insulin Resistance; Islets of Langerhans; I | 1987 |
Lactic acidosis and insulin resistance associated with epinephrine in a patient with noninsulin-dependent diabetes mellitus.
Topics: Acidosis, Lactic; Adult; Diabetes Mellitus, Type 2; Epinephrine; Humans; Insulin Resistance; Isoprot | 1988 |
Decreased tyrosine kinase activity of insulin receptor isolated from rat adipocytes rendered insulin-resistant by catecholamine treatment in vitro.
Topics: Adenosine Triphosphate; Adipose Tissue; Animals; In Vitro Techniques; Insulin; Insulin Resistance; I | 1986 |
Mechanism of insulin's stimulatory action on glucose transport in the isolated rat adipose cell.
Topics: Adipose Tissue; Animals; Biological Transport, Active; Carrier Proteins; Cell Compartmentation; Cell | 1985 |
Insulin-receptor interaction in the obese-hyperglycemic mouse. A model of insulin resistance.
Topics: Animals; Cell Fractionation; Cell Membrane; Electrophoresis, Disc; Genetics; Glucagon; Growth Hormon | 1973 |
The effect of oxytetracycline on insulin resistance in obese mice.
Topics: Animals; Blood Glucose; Cell Membrane; Diet; Glucose Tolerance Test; Insulin; Insulin Resistance; Is | 1974 |
Role of beta-adrenergic receptors in counterregulation to insulin-induced hypoglycemia.
Topics: Animals; Blood Glucose; Epinephrine; Fatty Acids, Nonesterified; Glucose; Glycerol; Humans; Hypoglyc | 1968 |