Page last updated: 2024-10-29

isoproterenol and Injury, Myocardial Reperfusion

isoproterenol has been researched along with Injury, Myocardial Reperfusion in 88 studies

Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.

Research Excerpts

ExcerptRelevanceReference
"After administration of isoproterenol under Ca(2+) loading, fatal VA frequently occurred in the vehicle (9 of 10 animals, 90%) and diltiazem (8 of 10, 80%) groups, and K201 significantly suppressed the incidences of arrhythmia and mortality (2 of 10, 20%)."7.79Protective effect of K201 on isoproterenol-induced and ischemic-reperfusion-induced ventricular arrhythmias in the rat: comparison with diltiazem. ( Inoue, T; Kaneko, N; Matsuda, R; Nishino, S; Oda, K; Otani, N, 2013)
"Aspirin was more effective than L-arginine in prolonging prothrombin time."5.37Protective effect of L-arginine in experimentally induced myocardial ischemia: comparison with aspirin. ( Abdel Maksoud, SM; El-Maraghy, SA; Gad, MZ; Saleh, AI, 2011)
"On the basis of preliminary studies and references of relevant literature about Sheng-Mai-San for myocardial ischemia, we chose three representative components (ginsenoside Rb1 (G), ruscogenin (R) and schisandrin (S)) for the optimization design studies."3.88A Strategy for Optimizing the Combination of Active Components Based on Chinese Medicinal Formula Sheng-Mai-San for Myocardial Ischemia. ( Chu, C; Fan, XX; Kou, JP; Li, F; Yu, BY; Zhang, Y, 2018)
"After administration of isoproterenol under Ca(2+) loading, fatal VA frequently occurred in the vehicle (9 of 10 animals, 90%) and diltiazem (8 of 10, 80%) groups, and K201 significantly suppressed the incidences of arrhythmia and mortality (2 of 10, 20%)."3.79Protective effect of K201 on isoproterenol-induced and ischemic-reperfusion-induced ventricular arrhythmias in the rat: comparison with diltiazem. ( Inoue, T; Kaneko, N; Matsuda, R; Nishino, S; Oda, K; Otani, N, 2013)
" were screened with mice model of acute myocardial hypoxia induced by isoproterenol and pituitrin, eight compounds, i."3.77Anti-hypoxia activity and related components of Rhodobryum giganteum par. ( Cai, Y; Chen, R; Lu, X; Lu, Y; Wei, Q, 2011)
" We investigated the effects of cinaciguat on myocardial infarction induced by isoproterenol in rats."3.75Pharmacological activation of soluble guanylate cyclase protects the heart against ischemic injury. ( Barnucz, E; Hirschberg, K; Karck, M; Korkmaz, S; Loganathan, S; Neugebauer, P; Páli, S; Radovits, T; Seidel, B; Szabó, G; Veres, G; Zöllner, S, 2009)
"These results indicate that (1) Both IPC and beta-PC elicit protection against apoptosis and necrosis, (2) activation of p38 MAPK is not a trigger of preconditioning against apoptosis and necrosis and (3) activation of p38 MAPK during reperfusion increases necrosis only if ischaemia is used to precondition hearts, but not with pharmacologic preconditioning with isoproterenol."3.73Inhibition of myocardial apoptosis by ischaemic and beta-adrenergic preconditioning is dependent on p38 MAPK. ( Hartley, S; Lochner, A; Marais, E; Moolman, JA; Van Wyk, J, 2006)
"The effects of SMP-300, an orally active, potent, and selective Na+/H+ exchange inhibitor, were evaluated and compared with those of nifedipine, propranolol, and nicorandil on three experimental angina models and on myocardial infarction in rats."3.71Effect of an orally active Na+/H+ exchange inhibitor, SMP-300, on experimental angina and myocardial infarction models in rats. ( Matsui, K; Ohashi, N; Sasabe, M; Yamamoto, S, 2002)
" A significant reversal of cardiac failure was attained in anaesthetised dogs subjected to propranolol induced cardiac insufficiency."3.68Cardiotonic activity of the water soluble forskolin derivative 8,13-epoxy-6 beta-(piperidinoacetoxy)- 1 alpha, 7 beta, 9 alpha-trihydroxy-labd- 14en-11-one. ( Ghate, AV; Linz, W; Rajagopalan, R; Schoelkens, BA; Subbarayan, P, 1993)
"Isoprenaline-induced cardiac hypertrophy can deteriorate to heart failure, which is a leading cause of mortality."1.62Vasonatrin peptide, a synthetic natriuretic peptide, attenuates myocardial injury and oxidative stress in isoprenaline-induced cardiomyocyte hypertrophy. ( Chang, P; Chen, W; Wang, J; Wang, X; Yu, J; Zhang, J; Zhang, X; Zhu, X, 2021)
"Pretreatment with baicalein significantly reversed these alterations induced by ISO administration."1.43Baicalein protects isoproterenol induced myocardial ischemic injury in male Wistar rats by mitigating oxidative stress and inflammation. ( Bodduluru, LN; Dahiya, V; Kasala, ER; Kumar, M; Lahkar, M, 2016)
"Isoproterenol (ISO) has been reported to inhibit high mobility group box 1 (HMGB1) protein release via heme oxygenase-1 (HO-1) induction in lipopolysaccharide (LPS)-activated RAW 264."1.40Isoproterenol‑mediated heme oxygenase‑1 induction inhibits high mobility group box 1 protein release and protects against rat myocardial ischemia/reperfusion injury in vivo. ( Fu, W; Hu, X; Jiang, H; Wang, J; Xie, J; Zhou, X, 2014)
"Intrauterine inflammation is a major contributor to preterm birth and has adverse effects on preterm neonatal cardiovascular physiology."1.40Exposure to intrauterine inflammation leads to impaired function and altered structure in the preterm heart of fetal sheep. ( Barton, SK; Bensley, JG; Black, MJ; De Matteo, R; Gill, AW; Harding, R; Kim, MY; Kluckow, M; Lingwood, BE; Moss, TJ; Parkington, HC; Polglase, GR; Tare, M, 2014)
"Aspirin was more effective than L-arginine in prolonging prothrombin time."1.37Protective effect of L-arginine in experimentally induced myocardial ischemia: comparison with aspirin. ( Abdel Maksoud, SM; El-Maraghy, SA; Gad, MZ; Saleh, AI, 2011)
"Pre-treatment with isoproterenol, adenosine, and the consecutive isoproterenol/adenosine treatment was also combined with the PKC inhibitor chelerythrine."1.36Consecutive pharmacological activation of PKA and PKC mimics the potent cardioprotection of temperature preconditioning. ( Halestrap, AP; Khaliulin, I; Parker, JE, 2010)
"Pretreatment with rutin daily for a period of 42 days to isoproterenol induced cardio toxic rats prevented the changes in the activities of these enzymes."1.36Preventive effects of rutin on lysosomal enzymes in isoproterenol induced cardio toxic rats: biochemical, histological and in vitro evidences. ( Priya, S; Stanely Mainzen Prince, P, 2010)
"Melatonin has potent cardioprotective properties."1.35Melatonin receptor-mediated protection against myocardial ischaemia/reperfusion injury: role of its anti-adrenergic actions. ( Genade, S; Genis, A; Huisamen, B; Lochner, A; Ytrehus, K, 2008)
" In integral animal experiments: acute myocardium ischemia model rats established by subcutaneous injection of isoprenaline were used, they were administered with MDG-1 in dosage of 10, 20 and 40 mg/kg respectively, and controlled with propranolol."1.34[Protective effect of Ophiopogonis polysaccharide MDG-1 on experimental myocardial ischemic rats]. ( Feng, Y; Xu, DS; Zheng, Q, 2007)
"In isoproterenol-treated female versus male hearts, there was also more endothelial NO synthase (eNOS) associated with cardiomyocyte caveolin-3, and more neuronal NOS (nNOS) translocation to caveolin-3 during ischemia/reperfusion."1.33Hypercontractile female hearts exhibit increased S-nitrosylation of the L-type Ca2+ channel alpha1 subunit and reduced ischemia/reperfusion injury. ( Bers, DM; Ginsburg, KS; Murphy, E; Picht, E; Steenbergen, C; Sun, J, 2006)
"The present study was designed to investigate the effects of chronic administration of the alcoholic extract of Terminalia arjuna (TAAE) bark on isoproterenol induced myocardial injury."1.32Cardioprotective effect of the alcoholic extract of Terminalia arjuna bark in an in vivo model of myocardial ischemic reperfusion injury. ( Bai, BR; Devaraj, SN; Gauthaman, K; Karthikeyan, K; Sathish, KS, 2003)
"Ischemia-induced ventricular arrhythmias were mostly reduced."1.31Reduction of infarct size by selective stimulation of prostaglandin EP(3)receptors in the reperfused ischemic pig heart. ( Hohlfeld, T; Meyer-Kirchrath, J; Schrör, K; Vogel, YC, 2000)
"Ventricular arrhythmias were evaluated as ventricular premature beats (VPBs), tachycardiac (VT) episodes and the incidences of VT and ventricular fibrillation (VF) during occlusion and following reperfusion."1.31Noradrenaline, infused locally, reduces arrhythmia severity during coronary artery occlusion in anaesthetised dogs. ( Parratt, JR; Végh, A, 2002)
" To determine the role of beta adrenergic stimulation before ischemia, a dose-response study was undertaken with isoprotelenol and milrinone at 37 degrees C."1.30Is the use of catecholamine before ischemic arrest safe? Effect of catecholamine on rat heart ischemia/reperfusion injury. ( Newling, R; Shimada, Y; Yamamoto, F; Yamamoto, H, 1999)
"To induce normotensive cardiac hypertrophy, male Wistar rats received injections of isoprenaline (5 mg/kg s."1.29[Recovery of healthy and hypertrophic hearts after global ischemia and graduated reperfusion]. ( Isselhard, W; Minor, T; Sturz, J, 1993)
"The incidence of arrhythmias observed upon restoration of control flow was increased by ISO when the action of endogenous adenosine was blocked with DPCPX."1.29Endogenous adenosine reduces depression of cardiac function induced by beta-adrenergic stimulation during low flow perfusion. ( Dobson, JG; Fenton, RA; Galeckas, KJ, 1995)
"When isoproterenol was added during ischemia, glucose uptake increased, glycogen decreased, and lactate release increased."1.29Metabolic fate of glucose in reversible low-flow ischemia of the isolated working rat heart. ( Bolukoglu, H; Carmical, SG; Chen, TM; Goodwin, GW; Guthrie, PH; Taegtmeyer, H, 1996)
"With regard to arrhythmias, arrhythmia score was remarkedly increased by all of 3 factors and various combinations except beta-Ago + Leu."1.29Orthogonal analysis of aggravating effects of alpha-, beta-agonists and leukocytes on reperfusion-induced arrhythmias and ventricular fibrillation in Langendorff's rat heart. ( An, LF; Dai, DZ; Huang, DY; Sun, RY, 1996)

Research

Studies (88)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.14)18.7374
1990's25 (28.41)18.2507
2000's33 (37.50)29.6817
2010's25 (28.41)24.3611
2020's4 (4.55)2.80

Authors

AuthorsStudies
Fan, CL1
Yao, ZH1
Ye, MN1
Fu, LL1
Zhu, GN1
Dai, Y1
Yao, XS1
Fan, S1
Zhao, H1
Liu, Y1
Zhang, P1
Wang, Y1
Xu, Y1
Gu, K1
Zhang, T1
Yu, J2
Qi, W1
Li, Y1
Zhang, Y3
Shen, J1
Wu, JM1
Hu, GM1
Li, MZ1
Cong, WW1
Feng, YN1
Wang, SX1
Li, ZJ1
Xu, M1
Dong, ED1
Zhang, YY1
Xiao, H1
Chang, P1
Zhang, X1
Chen, W1
Zhang, J1
Wang, J2
Wang, X1
Zhu, X1
Lewis, M1
Szobi, A1
Balaska, D1
Khaliulin, I2
Adameova, A1
Griffiths, E1
Orchard, CH1
Suleiman, MS1
Li, F1
Fan, XX1
Chu, C1
Kou, JP1
Yu, BY1
Li, G1
Yang, J1
Yang, C1
Zhu, M1
Jin, Y1
McNutt, MA1
Yin, Y1
Menezes-Rodrigues, FS1
Errante, PR1
Tavares, JGP1
Ferraz, RRN1
Gomes, WJ1
Taha, MO1
Scorza, CA1
Scorza, FA1
Caricati-Neto, A1
Fan, Q1
Chen, M2
Zuo, L1
Shang, X2
Huang, MZ1
Ciccarelli, M1
Raake, P1
Brinks, H1
Chuprun, KJ1
Dorn, GW1
Koch, WJ4
Gao, E4
Huang, ZM1
Fonseca, FV1
Hayashi, H1
Hoffman, NE1
Chuprun, JK2
Tian, X1
Tilley, DG1
Madesh, M1
Lefer, DJ1
Stamler, JS1
Pan, X1
Liu, J1
Nguyen, T1
Liu, C1
Sun, J3
Teng, Y1
Fergusson, MM1
Rovira, II1
Allen, M1
Springer, DA1
Aponte, AM1
Gucek, M1
Balaban, RS1
Murphy, E5
Finkel, T1
Hu, X1
Fu, W1
Xie, J1
Zhou, X1
Jiang, H1
Tare, M2
Bensley, JG1
Moss, TJ1
Lingwood, BE1
Kim, MY1
Barton, SK1
Kluckow, M1
Gill, AW1
De Matteo, R1
Harding, R1
Black, MJ1
Parkington, HC2
Polglase, GR1
Willis, BC1
Salazar-Cantú, A1
Silva-Platas, C1
Fernández-Sada, E1
Villegas, CA1
Rios-Argaiz, E1
González-Serrano, P1
Sánchez, LA1
Guerrero-Beltrán, CE1
García, N1
Torre-Amione, G1
García-Rivas, GJ1
Altamirano, J1
Zheng, YY1
Zhang, HH1
Yan, XX1
Qi, TY1
Zhang, LE1
Luo, DL1
Zhao, C1
Meng, F1
Geng, L1
Zhao, X1
Zhou, H1
Qin, S1
Kumar, M1
Kasala, ER1
Bodduluru, LN1
Dahiya, V1
Lahkar, M1
See Hoe, LE1
Schilling, JM1
Busija, AR1
Haushalter, KJ1
Ozberk, V1
Keshwani, MM1
Roth, DM1
Toit, ED1
Headrick, JP1
Patel, HH1
Peart, JN1
Smith, SB1
Xu, Z1
Novitskaya, T1
Zhang, B1
Chepurko, E1
Pu, XA1
Wheeler, DG1
Ziolo, M1
Gumina, RJ1
Li, L1
Li, J1
Drum, BM1
Chen, Y1
Yin, H1
Guo, X1
Luckey, SW1
Gilbert, ML1
McKnight, GS1
Scott, JD1
Santana, LF1
Liu, Q1
Genade, S1
Genis, A1
Ytrehus, K1
Huisamen, B1
Lochner, A3
Ross, JL1
Howlett, SE1
Asai, M1
Tsukamoto, O1
Minamino, T1
Asanuma, H1
Fujita, M1
Asano, Y1
Takahama, H1
Sasaki, H1
Higo, S1
Asakura, M1
Takashima, S1
Hori, M1
Kitakaze, M1
Yuan, J1
Wu, J1
Han, ZG1
Srivastava, G1
Mehta, JL1
Granata, R1
Trovato, L1
Gallo, MP1
Destefanis, S1
Settanni, F1
Scarlatti, F1
Brero, A1
Ramella, R1
Volante, M1
Isgaard, J1
Levi, R1
Papotti, M1
Alloatti, G1
Ghigo, E1
Maier, T1
Schreckenberg, R1
Schlüter, KD1
Ma, Y1
Cheng, WT1
Wu, S1
Wong, TM2
Korkmaz, S1
Radovits, T1
Barnucz, E1
Hirschberg, K1
Neugebauer, P1
Loganathan, S1
Veres, G1
Páli, S1
Seidel, B1
Zöllner, S1
Karck, M1
Szabó, G1
Ferreira, AJ1
Castro, CH1
Guatimosim, S1
Almeida, PW1
Gomes, ER1
Dias-Peixoto, MF1
Alves, MN1
Fagundes-Moura, CR1
Rentzsch, B1
Gava, E1
Almeida, AP1
Guimarães, AM1
Kitten, GT1
Reudelhuber, T1
Bader, M1
Santos, RA1
Parker, JE1
Halestrap, AP1
Cai, Y1
Lu, Y1
Chen, R1
Wei, Q1
Lu, X1
Stanely Mainzen Prince, P1
Priya, S1
Saleh, AI1
Abdel Maksoud, SM1
El-Maraghy, SA1
Gad, MZ1
Gayathri, V1
Ananthi, S1
Chandronitha, C1
Ramakrishnan, G1
Lakshmisundaram, R1
Sundaram, RL1
Vasanthi, HR1
Salie, R1
Moolman, JA2
Miller, SL1
Wallace, EM1
Sutherland, AE1
Yawno, T1
Coleman, HA1
Jenkin, G1
Otani, N1
Matsuda, R1
Oda, K1
Nishino, S1
Inoue, T1
Kaneko, N1
Cross, HR1
Steenbergen, C4
Karthikeyan, K1
Bai, BR1
Gauthaman, K1
Sathish, KS1
Devaraj, SN1
Eigel, BN1
Gursahani, H1
Hadley, RW1
Boucher, M2
Nim, S1
de Montigny, C1
Rousseau, G1
Imahashi, K2
London, RE1
Saini, HK2
Dhalla, NS3
Elimban, V1
Benter, IF1
Francis, I1
Khan, I1
Cojocel, C1
Juggi, JS1
Yousif, MH1
Canatan, H1
Alshawaf, EH1
Akhtar, S1
Pott, C1
Goldhaber, JI1
Philipson, KD1
Picht, E1
Ginsburg, KS1
Bers, DM1
Mohanty, I1
Arya, DS1
Gupta, SK1
Hartley, S1
Van Wyk, J1
Marais, E1
Hu, A1
Jiao, X1
Sharifi-Azad, S1
Grunwald, Z1
Ma, XL1
Sun, JZ1
Wölkart, G1
Kaber, G1
Kojda, G1
Brunner, F1
Dvorak, L1
Pirk, J1
Cerny, S1
Kovar, J1
Gauthaman, KK1
Saleem, MT1
Thanislas, PT1
Prabhu, VV1
Krishnamoorthy, KK1
Devaraj, NS1
Somasundaram, JS1
Yu, QJ1
Si, R1
Zhou, N1
Zhang, HF1
Guo, WY1
Wang, HC1
Gao, F1
Zheng, Q1
Feng, Y1
Xu, DS1
DeGeorge, BR1
Vinge, LE1
Martini, JS1
Raake, PW1
Harris, DM1
Kim, GW1
Soltys, S1
Eckhart, AD1
Asimakis, GK1
Inners-McBride, K1
Conti, VR1
Yang, CJ1
van den Ende, R1
Batink, HD1
Michel, MC1
van Zwieten, PA1
Evora, PR1
Pearson, PJ2
Schaff, HV2
Fullerton, DA1
Mitchell, MB1
McIntyre, RC1
Brown, JM1
Meng, X2
Campbell, DN1
Grover, FL1
Iwase, T1
Murakami, T1
Tomita, T1
Miki, S1
Nagai, K1
Sasayama, S1
Minor, T1
Isselhard, W1
Sturz, J1
Rajagopalan, R1
Ghate, AV1
Subbarayan, P1
Linz, W1
Schoelkens, BA1
Fenton, RA1
Galeckas, KJ1
Dobson, JG1
Bolukoglu, H1
Goodwin, GW1
Guthrie, PH1
Carmical, SG1
Chen, TM1
Taegtmeyer, H1
Nasa, Y1
Yabe, K1
Takeo, S1
Dorman, BH1
Hebbar, L1
Hinton, RB1
Roy, RC1
Spinale, FG2
Dupuis, JY1
Li, K1
Calderone, A1
Gosselin, H1
Yang, XP1
Anand-Srivastava, MB1
Teijeira, J1
Rouleau, JL1
D'Alonzo, AJ1
Zhu, JL1
Darbenzio, RB1
Dorso, CR1
Grover, GJ1
Cain, BS1
Meldrum, DR1
Pulido, EJ1
Banerjee, A1
Harken, AH1
Shimada, Y2
Yamamoto, F3
Yamamoto, H3
Oka, T1
Dai, DZ1
An, LF1
Huang, DY1
Sun, RY1
Persad, S1
Panagia, V1
Tejero-Taldo, MI1
Caffrey, JL1
Mallet, RT1
Piper, RD1
Li, FY1
Myers, ML1
Sibbald, WJ1
Newling, R1
Wildhirt, SM1
Weismueller, S1
Schulze, C1
Conrad, N1
Kornberg, A1
Reichart, B1
Hohlfeld, T1
Meyer-Kirchrath, J1
Vogel, YC1
Schrör, K1
Li, HY1
Bian, JS1
Kwan, YW1
Yamamoto, S1
Matsui, K1
Sasabe, M1
Ohashi, N1
Li, XF1
Yang, Y1
Gao, LR1
Qi, YF1
Li, ZQ1
Tang, CS1
Végh, A1
Parratt, JR1
Komai, H1
Tanaka, K1
Ichikawa, H1
Shibata, T1
Koide, A1
Ohashi, T1
Nakashima, N1
Kawashima, Y1
White, FC1
Boss, G1
Vanhoutte, PM1
Chess-Williams, R1
Coker, SJ1

Reviews

2 reviews available for isoproterenol and Injury, Myocardial Reperfusion

ArticleYear
Currying the heart: curcumin and cardioprotection.
    Journal of cardiovascular pharmacology and therapeutics, 2009, Volume: 14, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Antibiotics, Antineoplastic; Cardiovascular Agents; Curcumin; Dox

2009
Cellular and molecular therapeutic targets for treatment of contractile dysfunction after cardioplegic arrest.
    The Annals of thoracic surgery, 1999, Volume: 68, Issue:5

    Topics: Adenosine; Adenosine Triphosphate; Animals; Cardioplegic Solutions; Cells, Cultured; Heart Arrest, I

1999

Trials

1 trial available for isoproterenol and Injury, Myocardial Reperfusion

ArticleYear
The role of leukocyte depleting filters in heart transplantation: early outcomes in prospective, randomized clinical trial.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2006, Volume: 30, Issue:4

    Topics: Adult; Biomarkers; Cardiac Pacing, Artificial; Cardiopulmonary Bypass; Chi-Square Distribution; Crea

2006

Other Studies

85 other studies available for isoproterenol and Injury, Myocardial Reperfusion

ArticleYear
Fuziline alleviates isoproterenol-induced myocardial injury by inhibiting ROS-triggered endoplasmic reticulum stress via PERK/eIF2α/ATF4/Chop pathway.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:2

    Topics: Aconitum; Activating Transcription Factor 4; Adrenergic beta-Agonists; Alkaloids; Animals; Apoptosis

2020
Isoproterenol Triggers ROS/P53/S100-A9 Positive Feedback to Aggravate Myocardial Damage Associated with Complement Activation.
    Chemical research in toxicology, 2020, 10-19, Volume: 33, Issue:10

    Topics: Animals; Calgranulin B; Cells, Cultured; Isoproterenol; Male; Myocardial Contraction; Myocardial Rep

2020
Membrane nanotubes facilitate the propagation of inflammatory injury in the heart upon overactivation of the β-adrenergic receptor.
    Cell death & disease, 2020, 11-07, Volume: 11, Issue:11

    Topics: Adrenergic beta-Agonists; Animals; Animals, Newborn; Cell Membrane; Fibroblasts; Heart; Inflammation

2020
Vasonatrin peptide, a synthetic natriuretic peptide, attenuates myocardial injury and oxidative stress in isoprenaline-induced cardiomyocyte hypertrophy.
    Peptides, 2021, Volume: 137

    Topics: Animals; Animals, Newborn; Atrial Natriuretic Factor; Cardiomegaly; Cardiotonic Agents; Cyclic GMP;

2021
Consecutive Isoproterenol and Adenosine Treatment Confers Marked Protection against Reperfusion Injury in Adult but Not in Immature Heart: A Role for Glycogen.
    International journal of molecular sciences, 2018, Feb-07, Volume: 19, Issue:2

    Topics: Adenosine; Age Factors; Animals; Biomarkers; Cardiotonic Agents; Glycogen; Heart; Hemodynamics; Isch

2018
A Strategy for Optimizing the Combination of Active Components Based on Chinese Medicinal Formula Sheng-Mai-San for Myocardial Ischemia.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 45, Issue:4

    Topics: Animals; Creatine Kinase, MB Form; Cyclooctanes; Disease Models, Animal; Drug Combinations; Drugs, C

2018
PTENα regulates mitophagy and maintains mitochondrial quality control.
    Autophagy, 2018, Volume: 14, Issue:10

    Topics: Animals; Autophagy; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cardiomegaly; Gene Deletion; HEK293 C

2018
Pharmacological modulation of b-adrenoceptors as a new cardioprotective strategy for therapy of myocardial dysfunction induced by ischemia and reperfusion.
    Acta cirurgica brasileira, 2019, Volume: 34, Issue:5

    Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Agonists; Animals; Atenolol; Biomarkers; Blo

2019
Myocardial Ablation of G Protein-Coupled Receptor Kinase 2 (GRK2) Decreases Ischemia/Reperfusion Injury through an Anti-Intrinsic Apoptotic Pathway.
    PloS one, 2013, Volume: 8, Issue:6

    Topics: Animals; Apoptosis; bcl-X Protein; Cytochromes c; G-Protein-Coupled Receptor Kinase 2; Hemodynamics;

2013
Convergence of G protein-coupled receptor and S-nitrosylation signaling determines the outcome to cardiac ischemic injury.
    Science signaling, 2013, Oct-29, Volume: 6, Issue:299

    Topics: Adrenergic beta-Agonists; Animals; Blotting, Western; Cells, Cultured; G-Protein-Coupled Receptor Ki

2013
The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter.
    Nature cell biology, 2013, Volume: 15, Issue:12

    Topics: Animals; Apoptosis; Calcium; Calcium Channels; Cardiotonic Agents; Cells, Cultured; Exercise Toleran

2013
Isoproterenol‑mediated heme oxygenase‑1 induction inhibits high mobility group box 1 protein release and protects against rat myocardial ischemia/reperfusion injury in vivo.
    Molecular medicine reports, 2014, Volume: 9, Issue:5

    Topics: Adrenergic beta-Agonists; Animals; Creatine Kinase; Disease Models, Animal; Heme Oxygenase-1; Hemody

2014
Exposure to intrauterine inflammation leads to impaired function and altered structure in the preterm heart of fetal sheep.
    Clinical science (London, England : 1979), 2014, Volume: 127, Issue:9

    Topics: Adrenergic beta-Agonists; Animals; Female; Fetal Heart; Gene Expression Regulation, Developmental; H

2014
Impaired oxidative metabolism and calcium mishandling underlie cardiac dysfunction in a rat model of post-acute isoproterenol-induced cardiomyopathy.
    American journal of physiology. Heart and circulatory physiology, 2015, Mar-01, Volume: 308, Issue:5

    Topics: Adrenergic Agonists; Animals; Calcium Signaling; Calcium-Binding Proteins; Cardiomyopathies; Cells,

2015
Protective effect of low dose gadolinium chloride against isoproterenol-induced myocardial injury in rat.
    Apoptosis : an international journal on programmed cell death, 2015, Volume: 20, Issue:9

    Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Apoptosis; Arachidonic Acid; Bronchodilator Age

2015
Cardiac-protective effects and the possible mechanisms of alatamine during acute myocardial ischemia.
    Canadian journal of physiology and pharmacology, 2016, Volume: 94, Issue:4

    Topics: Animals; Apoptosis; Caspase 3; Creatine Kinase, MB Form; Emodin; Heart Ventricles; Isoproterenol; Ma

2016
Baicalein protects isoproterenol induced myocardial ischemic injury in male Wistar rats by mitigating oxidative stress and inflammation.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2016, Volume: 65, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Cardiotonic Agents; Catalase; Creatine Kinase, MB For

2016
Chronic β1-adrenoceptor blockade impairs ischaemic tolerance and preconditioning in murine myocardium.
    European journal of pharmacology, 2016, Oct-15, Volume: 789

    Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Dose-Response Relationship, Drug; Heart Rate; Ische

2016
Impact of cardiac-specific expression of CD39 on myocardial infarct size in mice.
    Life sciences, 2017, Jun-15, Volume: 179

    Topics: Animals; Antigens, CD; Apyrase; Calcium; Disease Models, Animal; Echocardiography; Gene Expression;

2017
Loss of AKAP150 promotes pathological remodelling and heart failure propensity by disrupting calcium cycling and contractile reserve.
    Cardiovascular research, 2017, Volume: 113, Issue:2

    Topics: A Kinase Anchor Proteins; Animals; Calcineurin; Calcium Signaling; Calcium-Binding Proteins; Cardiom

2017
Melatonin receptor-mediated protection against myocardial ischaemia/reperfusion injury: role of its anti-adrenergic actions.
    Journal of pineal research, 2008, Volume: 45, Issue:4

    Topics: Adrenergic Antagonists; Animals; Colforsin; Cyclic AMP; Guanylate Cyclase; Heart; Indoles; Isoproter

2008
Beta-adrenoceptor stimulation exacerbates detrimental effects of ischemia and reperfusion in isolated guinea pig ventricular myocytes.
    European journal of pharmacology, 2009, Jan-14, Volume: 602, Issue:2-3

    Topics: Adrenergic beta-Agonists; Animals; Calcium; Cell Survival; Guinea Pigs; Heart Ventricles; Homeostasi

2009
PKA rapidly enhances proteasome assembly and activity in in vivo canine hearts.
    Journal of molecular and cellular cardiology, 2009, Volume: 46, Issue:4

    Topics: Animals; Cyclic AMP-Dependent Protein Kinases; Dogs; Enzyme Activation; In Vitro Techniques; Isoprot

2009
[Fenofibrate improves energy metabolism and attenuates isoproterenol induced acute myocardial ischemic injury in rats via PPAR alpha activation].
    Zhonghua xin xue guan bing za zhi, 2008, Volume: 36, Issue:9

    Topics: Animals; Disease Models, Animal; Energy Metabolism; Fenofibrate; Isoproterenol; Male; Myocardial Isc

2008
Growth hormone-releasing hormone promotes survival of cardiac myocytes in vitro and protects against ischaemia-reperfusion injury in rat heart.
    Cardiovascular research, 2009, Jul-15, Volume: 83, Issue:2

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Apoptosis; Calcium; Caspase 3; Cell Line; Cell

2009
Effect of preischemic beta-adrenoceptor stimulation on postischemic contractile dysfunction.
    Life sciences, 2009, Mar-27, Volume: 84, Issue:13-14

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Female; Hemodynamics; Hyperte

2009
Oestrogen confers cardioprotection by suppressing Ca2+/calmodulin-dependent protein kinase II.
    British journal of pharmacology, 2009, Volume: 157, Issue:5

    Topics: Adrenergic beta-Agonists; Animals; Apoptosis; Benzylamines; Calcium Signaling; Calcium-Calmodulin-De

2009
Pharmacological activation of soluble guanylate cyclase protects the heart against ischemic injury.
    Circulation, 2009, Aug-25, Volume: 120, Issue:8

    Topics: Adrenergic beta-Agonists; Animals; Benzoates; Cardiotonic Agents; Cyclic AMP; Cyclic GMP; Cyclooxyge

2009
Attenuation of isoproterenol-induced cardiac fibrosis in transgenic rats harboring an angiotensin-(1-7)-producing fusion protein in the heart.
    Therapeutic advances in cardiovascular disease, 2010, Volume: 4, Issue:2

    Topics: Angiotensin I; Animals; Arrhythmias, Cardiac; Blood Pressure; Calcium; Disease Models, Animal; Fibro

2010
Consecutive pharmacological activation of PKA and PKC mimics the potent cardioprotection of temperature preconditioning.
    Cardiovascular research, 2010, Nov-01, Volume: 88, Issue:2

    Topics: Adenosine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cardiotonic Agents; Cycli

2010
Anti-hypoxia activity and related components of Rhodobryum giganteum par.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2011, Jan-15, Volume: 18, Issue:2-3

    Topics: Animals; Bryophyta; Cinnamates; Coumarins; Disease Models, Animal; Hypoxia; Isoproterenol; Male; Mic

2011
Preventive effects of rutin on lysosomal enzymes in isoproterenol induced cardio toxic rats: biochemical, histological and in vitro evidences.
    European journal of pharmacology, 2010, Dec-15, Volume: 649, Issue:1-3

    Topics: Animals; Antioxidants; Biomarkers; Cardiotonic Agents; Cardiotoxins; Creatine Kinase, MB Form; Heart

2010
Protective effect of L-arginine in experimentally induced myocardial ischemia: comparison with aspirin.
    Journal of cardiovascular pharmacology and therapeutics, 2011, Volume: 16, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Arginine; Aspirin; Cardiotonic Agents; Chol

2011
Cardioprotective effect of Nerium oleander flower against isoproterenol-induced myocardial oxidative stress in experimental rats.
    Journal of cardiovascular pharmacology and therapeutics, 2011, Volume: 16, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Biomarkers; Cardiotonic Agents; Dose-Response Relationship, Drug;

2011
The role of β-adrenergic receptors in the cardioprotective effects of beta-preconditioning (βPC).
    Cardiovascular drugs and therapy, 2011, Volume: 25, Issue:1

    Topics: A Kinase Anchor Proteins; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Ethanolami

2011
Glucocorticoid treatment does not alter early cardiac adaptations to growth restriction in preterm sheep fetuses.
    BJOG : an international journal of obstetrics and gynaecology, 2012, Volume: 119, Issue:8

    Topics: Adaptation, Physiological; Adrenergic beta-Agonists; Analysis of Variance; Animals; Betamethasone; B

2012
Protective effect of K201 on isoproterenol-induced and ischemic-reperfusion-induced ventricular arrhythmias in the rat: comparison with diltiazem.
    Journal of cardiovascular pharmacology and therapeutics, 2013, Volume: 18, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Cardiotonic Agents; Diltiazem; Isoproterenol; Male; Myocardial Reperf

2013
Ca(2+) loading and adrenergic stimulation reveal male/female differences in susceptibility to ischemia-reperfusion injury.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:2

    Topics: Adrenergic beta-Agonists; Animals; Calcium; Disease Susceptibility; Dose-Response Relationship, Drug

2002
Cardioprotective effect of the alcoholic extract of Terminalia arjuna bark in an in vivo model of myocardial ischemic reperfusion injury.
    Life sciences, 2003, Oct-10, Volume: 73, Issue:21

    Topics: Administration, Oral; Animals; Catalase; Disease Models, Animal; Dose-Response Relationship, Drug; G

2003
Na+/Ca2+ exchanger plays a key role in inducing apoptosis after hypoxia in cultured guinea pig ventricular myocytes.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 287, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Apoptosis; Cells, Cultured; Endothelin

2004
Alterations of beta-adrenoceptor responsiveness in postischemic myocardium after 72 h of reperfusion.
    European journal of pharmacology, 2004, Jul-14, Volume: 495, Issue:2-3

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; beta-Adrenergic Receptor Kinases; Body Tempera

2004
Male/female differences in intracellular Na+ regulation during ischemia/reperfusion in mouse heart.
    Journal of molecular and cellular cardiology, 2004, Volume: 37, Issue:3

    Topics: Animals; Cardiotonic Agents; Female; Isoproterenol; Male; Mice; Myocardial Contraction; Myocardial I

2004
Defective calcium handling in cardiomyocytes isolated from hearts subjected to ischemia-reperfusion.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2005
Attenuation of extracellular ATP response in cardiomyocytes isolated from hearts subjected to ischemia-reperfusion.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 289, Issue:2

    Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Calcium; Catalase; Cell Hypoxia; Cell Sep

2005
Signal transduction involving Ras-GTPase contributes to development of hypertension and end-organ damage in spontaneously hypertensive rats-treated with L-NAME.
    Pharmacological research, 2005, Volume: 52, Issue:5

    Topics: Animals; Blood Pressure; Collagen Type III; Hypertension; Isoproterenol; Kidney; Myocardial Reperfus

2005
Cardiac-specific ablation of the Na+-Ca2+ exchanger confers protection against ischemia/reperfusion injury.
    Circulation research, 2005, Oct-28, Volume: 97, Issue:9

    Topics: Animals; Calcium; Energy Metabolism; Isoproterenol; Mice; Mice, Knockout; Myocardial Contraction; My

2005
Hypercontractile female hearts exhibit increased S-nitrosylation of the L-type Ca2+ channel alpha1 subunit and reduced ischemia/reperfusion injury.
    Circulation research, 2006, Feb-17, Volume: 98, Issue:3

    Topics: Animals; Calcium Channels, L-Type; Cardiotonic Agents; Female; Isoproterenol; Male; Mice; Mice, Knoc

2006
Effect of Curcuma longa and Ocimum sanctum on myocardial apoptosis in experimentally induced myocardial ischemic-reperfusion injury.
    BMC complementary and alternative medicine, 2006, Feb-19, Volume: 6

    Topics: Administration, Oral; Animals; Apoptosis; bcl-2-Associated X Protein; Curcuma; Hemodynamics; Isoprot

2006
Inhibition of myocardial apoptosis by ischaemic and beta-adrenergic preconditioning is dependent on p38 MAPK.
    Cardiovascular drugs and therapy, 2006, Volume: 20, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Anisomycin; Apoptosis; Enzyme Activators; Imidazoles; In Vitro Te

2006
Chronic beta-adrenergic receptor stimulation induces cardiac apoptosis and aggravates myocardial ischemia/reperfusion injury by provoking inducible nitric-oxide synthase-mediated nitrative stress.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 318, Issue:2

    Topics: Adrenergic beta-Agonists; Animals; Apoptosis; Blotting, Western; C-Reactive Protein; Heart; Immunohi

2006
Role of endogenous hydrogen peroxide in cardiovascular ischaemia/reperfusion function: studies in mouse hearts with catalase-overexpression in the vascular endothelium.
    Pharmacological research, 2006, Volume: 54, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Blood Pressure; Catalase; Endothelium,

2006
Cardioprotective effect of the Hibiscus rosa sinensis flowers in an oxidative stress model of myocardial ischemic reperfusion injury in rat.
    BMC complementary and alternative medicine, 2006, Sep-20, Volume: 6

    Topics: Administration, Oral; Animals; Antioxidants; Catalase; Disease Models, Animal; Flowers; Glutathione;

2006
Insulin inhibits beta-adrenergic action in ischemic/reperfused heart: a novel mechanism of insulin in cardioprotection.
    Apoptosis : an international journal on programmed cell death, 2008, Volume: 13, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Apoptosis; Calcium; Calcium-Binding Proteins; Cardiotonic Agen

2008
[Protective effect of Ophiopogonis polysaccharide MDG-1 on experimental myocardial ischemic rats].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2007, Volume: 27, Issue:12

    Topics: Animals; Cardiotonic Agents; Coronary Circulation; Drugs, Chinese Herbal; Electrocardiography; Guine

2007
Targeted inhibition of cardiomyocyte Gi signaling enhances susceptibility to apoptotic cell death in response to ischemic stress.
    Circulation, 2008, Mar-18, Volume: 117, Issue:11

    Topics: Adrenergic beta-Agonists; Animals; Apoptosis; Cells, Cultured; GTP-Binding Protein alpha Subunit, Gi

2008
Transient beta adrenergic stimulation can precondition the rat heart against postischaemic contractile dysfunction.
    Cardiovascular research, 1994, Volume: 28, Issue:11

    Topics: Adrenergic beta-Agonists; Animals; Arrhythmias, Cardiac; Glycogen; Heart; Isoproterenol; Male; Myoca

1994
Influence of ischaemia and reperfusion on cardiac signal transduction. G protein content, adenylyl cyclase activity, cyclic AMP content, and forskolin and dibutyryl cyclic AMP-induced inotropy in the rat Langendorff heart.
    Fundamental & clinical pharmacology, 1994, Volume: 8, Issue:5

    Topics: Adenylyl Cyclases; Animals; Bucladesine; Colforsin; Cyclic AMP; GTP-Binding Proteins; Heart; In Vitr

1994
Impaired endothelium-dependent relaxation after coronary reperfusion injury: evidence for G-protein dysfunction.
    The Annals of thoracic surgery, 1994, Volume: 57, Issue:6

    Topics: Acetylcholine; Adenosine Diphosphate; Aluminum Chloride; Aluminum Compounds; Animals; Calcimycin; Ca

1994
Mechanisms of coronary vasomotor dysfunction in the transplanted heart.
    The Annals of thoracic surgery, 1994, Volume: 58, Issue:1

    Topics: Acetylcholine; Animals; Cold Temperature; Coronary Vessels; Cyclic AMP; Cyclic GMP; Dogs; Endotheliu

1994
Ischemic preconditioning is associated with a delay in ischemia-induced reduction of beta-adrenergic signal transduction in rabbit hearts.
    Circulation, 1993, Volume: 88, Issue:6

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Colforsin; Female;

1993
[Recovery of healthy and hypertrophic hearts after global ischemia and graduated reperfusion].
    Annales de chirurgie, 1993, Volume: 47, Issue:8

    Topics: Adenine Nucleotides; Animals; Cardiomegaly; Heart Function Tests; Isoproterenol; Male; Myocardial Re

1993
Cardiotonic activity of the water soluble forskolin derivative 8,13-epoxy-6 beta-(piperidinoacetoxy)- 1 alpha, 7 beta, 9 alpha-trihydroxy-labd- 14en-11-one.
    Arzneimittel-Forschung, 1993, Volume: 43, Issue:3

    Topics: Adenosine Diphosphate; Anesthesia; Animals; Cardiotonic Agents; Cats; Colforsin; Cricetinae; Dogs; E

1993
Endogenous adenosine reduces depression of cardiac function induced by beta-adrenergic stimulation during low flow perfusion.
    Journal of molecular and cellular cardiology, 1995, Volume: 27, Issue:10

    Topics: Adenosine; Adrenergic beta-Agonists; Animals; Arrhythmias, Cardiac; Coronary Circulation; Epinephrin

1995
Metabolic fate of glucose in reversible low-flow ischemia of the isolated working rat heart.
    The American journal of physiology, 1996, Volume: 270, Issue:3 Pt 2

    Topics: Animals; Cardiotonic Agents; Glucose; Heart Rate; Isoproterenol; Male; Myocardial Ischemia; Myocardi

1996
Beta-adrenoceptor stimulation-mediated preconditioning-like cardioprotection in perfused rat hearts.
    Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-A

1997
Preservation of myocyte contractile function after hyperthermic cardioplegic arrest by activation of ATP-sensitive potassium channels.
    Circulation, 1997, Oct-07, Volume: 96, Issue:7

    Topics: Animals; Calcium; Cardioplegic Solutions; Cells, Cultured; Heart; Heart Arrest, Induced; Hot Tempera

1997
Beta-adrenergic signal transduction and contractility in the canine heart after cardiopulmonary bypass.
    Cardiovascular research, 1997, Volume: 36, Issue:2

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Analysis of Variance; Animals; Cardiopulmonary Bypass;

1997
Proarrhythmic effects of pinacidil are partially mediated through enhancement of catecholamine release in isolated perfused guinea-pig hearts.
    Journal of molecular and cellular cardiology, 1998, Volume: 30, Issue:2

    Topics: Adenosine Triphosphate; Adrenergic Agonists; Adrenergic beta-Antagonists; Animals; Arrhythmias, Card

1998
Therapeutic antidysrhythmic and functional protection in human atria.
    The Journal of surgical research, 1998, Volume: 76, Issue:2

    Topics: Adenosine; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Arrhythmias, Cardiac; Coronary Arter

1998
Effect of preischemic catecholamine treatment on ischemia-reperfusion injury of the myocardium: subtype, dose, and temperature dependency.
    Japanese circulation journal, 1998, Volume: 62, Issue:7

    Topics: Adrenergic beta-Agonists; Animals; Cardioplegic Solutions; Catecholamines; Heart Function Tests; In

1998
Orthogonal analysis of aggravating effects of alpha-, beta-agonists and leukocytes on reperfusion-induced arrhythmias and ventricular fibrillation in Langendorff's rat heart.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1996, Volume: 17, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Arrhythmias, Cardiac; In Vitro Techniq

1996
Role of H2O2 in changing beta-adrenoceptor and adenylyl cyclase in ischemia-reperfused hearts.
    Molecular and cellular biochemistry, 1998, Volume: 186, Issue:1-2

    Topics: Adenylyl Cyclases; Animals; GTP-Binding Proteins; Heart; Hydrogen Peroxide; In Vitro Techniques; Iso

1998
Pyruvate potentiates beta-adrenergic inotropism of stunned guinea-pig myocardium.
    Journal of molecular and cellular cardiology, 1998, Volume: 30, Issue:11

    Topics: Animals; Energy Metabolism; Guinea Pigs; Isoproterenol; Muscle Proteins; Myocardial Contraction; Myo

1998
Effects of isoproterenol on myocardial structure and function in septic rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 1999, Volume: 86, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Blood Cell Count; Blood Pressure; Coronary Circulation; Heart; He

1999
Is the use of catecholamine before ischemic arrest safe? Effect of catecholamine on rat heart ischemia/reperfusion injury.
    The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi, 1999, Volume: 47, Issue:7

    Topics: Adrenergic beta-Agonists; Animals; Dopamine; Epinephrine; In Vitro Techniques; Isoproterenol; Male;

1999
Inducible nitric oxide synthase activation after ischemia/reperfusion contributes to myocardial dysfunction and extent of infarct size in rabbits: evidence for a late phase of nitric oxide-mediated reperfusion injury.
    Cardiovascular research, 1999, Aug-15, Volume: 43, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Enzyme Activation; Enzyme Inhibitors; Guanidines; Hemodynamics; I

1999
Reduction of infarct size by selective stimulation of prostaglandin EP(3)receptors in the reperfused ischemic pig heart.
    Journal of molecular and cellular cardiology, 2000, Volume: 32, Issue:2

    Topics: Action Potentials; Adenylyl Cyclases; Adrenergic beta-Agonists; Alprostadil; Animals; Arrhythmias, C

2000
Enhanced responses to 17beta-estradiol in rat hearts treated with isoproterenol: involvement of a cyclic AMP-dependent pathway.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 293, Issue:2

    Topics: Adrenergic beta-Agonists; Animals; Arrhythmias, Cardiac; Blood Pressure; Calcium Channels; Cell Memb

2000
Effect of an orally active Na+/H+ exchange inhibitor, SMP-300, on experimental angina and myocardial infarction models in rats.
    Journal of cardiovascular pharmacology, 2002, Volume: 39, Issue:2

    Topics: Administration, Oral; Angina Pectoris; Animals; Azocines; Coronary Disease; Electrocardiography; Iso

2002
[Ameliorative effects of adrenomedullin on rat cardiac sarcoplasmic reticulum injured by isoproterenol].
    Sheng li xue bao : [Acta physiologica Sinica], 2001, Volume: 53, Issue:5

    Topics: Adenosine Triphosphatases; Adrenomedullin; Animals; Calcium; Calcium Channels; In Vitro Techniques;

2001
Noradrenaline, infused locally, reduces arrhythmia severity during coronary artery occlusion in anaesthetised dogs.
    Cardiovascular research, 2002, Volume: 55, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Analysis of Variance; Anesthesia; Animals; Arrh

2002
Harmful effects of inotropic agents on myocardial protection.
    The Annals of thoracic surgery, 1991, Volume: 52, Issue:4

    Topics: Animals; Body Temperature; Bucladesine; Calcium; Cardiotonic Agents; Creatine Kinase; Diltiazem; Hem

1991
Inotropic interventions during myocardial "stunning" in the pig.
    The American journal of cardiovascular pathology, 1990, Volume: 3, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antibodies, Monoclonal; Calcium; Female; Iso

1990
Acute impairment of endothelium-dependent relaxations to aggregating platelets following reperfusion injury in canine coronary arteries.
    Circulation research, 1990, Volume: 67, Issue:2

    Topics: Acetylcholine; Adenosine Diphosphate; Animals; Calcimycin; Coronary Vessels; Dinoprost; Dogs; Endoth

1990
Ventricular fibrillation is reduced in hypothyroid rats with enhanced myocardial alpha-adrenoceptor responsiveness.
    British journal of pharmacology, 1989, Volume: 98, Issue:1

    Topics: Anesthesia; Animals; Coronary Disease; Hypothyroidism; Isoproterenol; Male; Myocardial Reperfusion I

1989