isoproterenol has been researched along with Inflammation in 119 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Anethole may retain a cardio-protective potential by controlling myocardial oxidative stress (through Nrf2 pathway) and diminishing inflammation and apoptosis via the TLR4/MYD88 pathway." | 8.12 | Anethole's effects against myocardial infarction: The role of TLR4/NFκB and Nrf2/HO1 pathways. ( Mohamed, ME; Younis, NS, 2022) |
| "In the present study, we assessed the therapeutic potential of Biochanin-A (BCA) (10 mg/kg BW/day) pretreatment for 30 days on lipid metabolic abnormalities, proinflammatory cytokines and matrix metalloproteinase expression in isoproterenol (ISO)-induced myocardial infarction (MI) in rats." | 8.12 | Attenuation of lipid metabolic abnormalities, proinflammatory cytokines, and matrix metalloproteinase expression by biochanin-A in isoproterenol-induced myocardial infarction in rats. ( Chandrasekaran, P; Jansy Isabella, RAR; Ponmurugan, P; Sangeethadevi, G; Saravanan, G; Sengottuvelu, S; V V, SU; Vadivukkarasi, S, 2022) |
| " The study was conducted to examine the ability of amniotic membrane mesenchymal stem cells (AMSCs) for protection against isoproterenol (ISO)-induced myocardial injury and attempted to show the possible mechanisms by which AMSCs that can be linked to inhibition of inflammation by targeting inflammatory MAPK/NF-κB pathway." | 8.12 | Human amniotic membrane mesenchymal stem cells exert cardioprotective effects against isoproterenol (ISO)-induced myocardial injury through suppression of inflammation and modulation of inflammatory MAPK/NF-κB pathway. ( Aboutaleb, N; Naseroleslami, M, 2022) |
| " The present study aimed to investigate the effect of TQ on apoptotic parameters and MMP-9 expression in isoproterenol (ISP)-induced myocardial infarction (MI)." | 8.12 | Thymoquinone attenuates isoproterenol-induced myocardial infarction by inhibiting cytochrome C and matrix metalloproteinase-9 expression. ( Awad, A; Badr, AM; El-Bakly, WM; El-Demerdash, E; Medhet, M, 2022) |
| " Rats were induced MI by isoproterenol (100 mg/kg body weight) and then treated with valencene and cardiac sensitive markers, cardiac hypertrophy, oxidative stress, markers of inflammation, nuclear factor- κB inflammatory pathway, and myocardial infarct size was estimated/determined." | 8.12 | Valencene post-treatment exhibits cardioprotection via inhibiting cardiac hypertrophy, oxidative stress, nuclear factor- κB inflammatory pathway, and myocardial infarct size in isoproterenol-induced myocardial infarcted rats; A molecular study. ( Berlin Grace, VM; Shervin Prince, S; Stanely Mainzen Prince, P, 2022) |
| "This study has explored the fact that geraniol prevents isoproterenol (ISO)-induced oxidative stress and inflammation-mediated myocardial infarction (MI) through enhanced expression of peroxiredoxin-1 (Prdx-1) in experimental animal models." | 8.12 | Geraniol enhances peroxiredoxin-1, and prevents isoproterenol-induced oxidative stress and inflammation associated with myocardial infarction in experimental animal models. ( Balupillai, A; David, E; Ranganathan, B; Saravanan, K; Wan, J; Zou, G, 2022) |
| "Earlier studies reported that long-term treatment with thymoquinone (TQ) at a high dose (20 mg/kg) exerts a cardioprotective effect against isoproterenol (ISO)-triggered myocardial infarction (MI) in rats." | 8.12 | Thymoquinone Produces Cardioprotective Effect in β-Receptor Stimulated Myocardial Infarcted Rats via Subsiding Oxidative Stress and Inflammation. ( Agrawal, Y; Goyal, SN; Nagoor Meeran, MF; Nakhate, KT; Ojha, S; Patil, CR; Rathod, S; Sherikar, A, 2022) |
| "Inflammation can contribute to the initiation and progression of atrial fibrillation (AF), and pinocembrin can suppress downstream inflammatory cytokine production by inhibiting the inflammation pathway." | 8.12 | Pinocembrin alleviates the susceptibility to atrial fibrillation in isoproterenol-induced rats. ( Chen, X; Liu, Z; Wan, W; Yang, B; Ye, T; Yu, Y; Zhang, C, 2022) |
| "This study aimed to investigate the antihyperlipidemic and anti-inflammatory effect of zingiberene (ZBN) on isoproterenol-(ISO) induced myocardial infarction in rats." | 8.02 | Anti-inflammatory and anti-apoptotic effect of zingiberene on isoproterenol-induced myocardial infarction in experimental animals. ( Govindasamy, K; Li, J; Thangaiyan, R; Wei, J, 2021) |
| "As rats develop myocardial infarction (MI) like lesions when injected with large doses of isoproterenol (ISO), this investigation was designed to evaluate the dose-dependent effects of thymoquinone (TQ) on ISO-induced myocardial injury in rats." | 8.02 | Thymoquinone dose-dependently attenuates myocardial injury induced by isoproterenol in rats via integrated modulations of oxidative stress, inflammation, apoptosis, autophagy, and fibrosis. ( Elhadidy, WF; Farag, MM; Khalifa, AA; Rashad, RM, 2021) |
| "HC), a novel potent synthesized coumarin, on isoproterenol- (ISO-) induced myocardial infarction (MI) in rats." | 7.96 | (E)-N'-(1-(7-Hydroxy-2-Oxo-2H-Chromen-3-Yl) Ethylidene) Benzohydrazide, a Novel Synthesized Coumarin, Ameliorates Isoproterenol-Induced Myocardial Infarction in Rats through Attenuating Oxidative Stress, Inflammation, and Apoptosis. ( Abid, S; Allouche, N; Ammar, H; Elmufti, A; Feriani, A; Ghazouani, L; Hajji, R; Khdhiri, E; Mnafgui, K; Tir, M; Tlili, N, 2020) |
| " In the present study, we report that wogonin nanoparticles (Wog np) protect Isoproterenol (ISO) induced Myocardial Infarction (MI) rats." | 7.96 | Cardio protective role of wogonin loaded nanoparticle against isoproterenol induced myocardial infarction by moderating oxidative stress and inflammation. ( Bei, W; Chen, N; Jing, L, 2020) |
| "We investigated the protective effect of tetramethylpyrazine (TMP) on injury related to acute myocardial ischemia (AMI) induced by isoproterenol (ISO)." | 7.91 | Tetramethylpyrazine exerts a protective effect against injury from acute myocardial ischemia by regulating the PI3K/Akt/GSK-3β signaling pathway. ( Chen, B; Huang, DD; Huang, HH; Li, DG; Yang, Q; Yuan, CL; Zhang, LM, 2019) |
| " The present study was directed to investigate the effect of ATV pre- and post-treatment in isoproterenol (ISO)-induced cardiotoxicity in rats." | 7.88 | Paradoxical effects of atorvastatin in isoproterenol-induced cardiotoxicity in rats: Role of oxidative stress and inflammation. ( Ahmed, LA; Attalla, DM; Khattab, MM; Zaki, HF, 2018) |
| " This study was performed to investigate the effects of syrigaldehyde (SYD), a phytochemical against isoproterenol (ISO) induced cardiotoxicity model." | 7.88 | Protective effect of syringaldehyde on biomolecular oxidation, inflammation and histopathological alterations in isoproterenol induced cardiotoxicity in rats. ( Akhtar, K; Mateen, S; Moin, S; Mubeena Mariyath, PM; Naeem, SS; Rizvi, W; Shahzad, S, 2018) |
| "The present study was designed to evaluate the cardioprotective potential of edaravone on oxidative stress, anti-apoptotic, anti-inflammatory and ultrastructure findings in isoproterenol (ISO) induced myocardial infarction (MI) in rats." | 7.81 | Edaravone protects rats against oxidative stress and apoptosis in experimentally induced myocardial infarction: Biochemical and ultrastructural evidence. ( Akhtar, M; Akhtar, MS; Ali, J; Haque, SE; Hassan, MQ; Najmi, AK, 2015) |
| " In this study, we investigated whether baicalin ameliorates isoproterenol-induced acute myocardial infarction and its mechanism." | 7.81 | Baicalin ameliorates isoproterenol-induced acute myocardial infarction through iNOS, inflammation and oxidative stress in rat. ( Chen, H; Ruan, H; Wang, J; Xu, Y; Zhao, W, 2015) |
| "We have previously shown that pentoxifylline (PTX) protects from vascular complications associated with insulin resistance (IR)." | 7.80 | Pentoxifylline alleviates cardiac ischemia and dysfunction following experimental angina in insulin resistance. ( Azhar, A; El-Bassossy, HM, 2014) |
| " Rehmannia complex (Reh) a famous prescription in China and the triterpene acids (TTA) isolated from Reh may relieve the isoproterenol (ISO) induced chronic inflammation in the brain, compared with APO." | 7.80 | Isoproterenol induced stressful reactions in the brain are characterized by inflammation due to activation of NADPH oxidase and ER stress: attenuated by Apocynin, Rehmannia complex and Triterpene acids. ( Cong, XD; Dai, DZ; Dai, Y; Du, RH; Li, Y; Mo, GL, 2014) |
| "Persistent β-adrenergic receptor stimulation with isoproterenol is associated with cardiac hypertrophy as well as cardiac synthesis of angiotensin II." | 7.78 | Spironolactone prevents alterations associated with cardiac hypertrophy produced by isoproterenol in rats: involvement of serum- and glucocorticoid-regulated kinase type 1. ( Ballesteros, S; Cachofeiro, V; Davel, AP; de las Heras, N; Lahera, V; Martín-Fernández, B; Miana, M; Rossoni, LV; Valero-Muñoz, M; Vassallo, D, 2012) |
| "The influence of Isoproterenol on the number of the different types of white blood cells appearing during the course of the Sephadex inflammation was investigated in rats." | 7.66 | The influence of a permanent isoproterenol (ISO) application on the dynamics of the Sephadex inflammation. ( Egger, G; Porta, S, 1979) |
| "6-Shogaol pretreatment decreased the activities of cardiac and lipid peroxidative markers and enhanced the antioxidant status in ISO-induced cardiac injury rats." | 5.72 | 6-Shogaol protects against isoproterenol-induced cardiac injury in rats through attenutating oxidative stress, inflammation, apoptosis and activating nuclear respiratory factor-2/heme oxygenase-1 signaling pathway. ( Hu, L; Li, H; Luo, W; Shen, J; Zhang, Y, 2022) |
| "Lycorine is an alkaloid with several beneficial biological properties." | 5.62 | Lycorine ameliorates isoproterenol-induced cardiac dysfunction mainly via inhibiting inflammation, fibrosis, oxidative stress and apoptosis. ( Fu, Y; Li, P; Wang, ZH; Wu, J; Wu, YX; Wu, ZX, 2021) |
| "Visnagin (VIS) is a natural bioactive component of Ammi visnaga, with promising radical scavenging and anti-inflammatory activities." | 5.62 | Visnagin prevents isoproterenol-induced myocardial injury by attenuating oxidative stress and inflammation and upregulating Nrf2 signaling in rats. ( Abukhalil, MH; Al-Amarat, W; Al-Swailmi, FK; Aladaileh, SH; Alanazi, KM; Alfwuaires, MA; Algefare, AI; Althunibat, OY; Hussein, OE; Kamel, EM; Mahmoud, AM; Saghir, SA, 2021) |
| "Piperine pretreatment significantly prevented these changes in ISO treated group." | 5.56 | The protective effect of piperine against isoproterenol-induced inflammation in experimental models of myocardial toxicity. ( Aliev, G; Beeraka, NM; Chubarev, VN; Dhivya, V; Gavryushova, LV; Huang, CY; Mikhaleva, LM; Minyaeva, NN; Tarasov, VV; Viswanadha, VP, 2020) |
| "Isoproterenol (ISO) has been widely used to establish cardiac injury in vivo and in vitro." | 5.46 | Shikonin ameliorates isoproterenol (ISO)-induced myocardial damage through suppressing fibrosis, inflammation, apoptosis and ER stress. ( Chen, DL; Wang, Z; Yang, J, 2017) |
| "Inflammation can contribute to the initiation and progression of atrial fibrillation (AF), and pinocembrin can suppress downstream inflammatory cytokine production by inhibiting the inflammation pathway." | 4.12 | Pinocembrin alleviates the susceptibility to atrial fibrillation in isoproterenol-induced rats. ( Chen, X; Liu, Z; Wan, W; Yang, B; Ye, T; Yu, Y; Zhang, C, 2022) |
| "Anethole may retain a cardio-protective potential by controlling myocardial oxidative stress (through Nrf2 pathway) and diminishing inflammation and apoptosis via the TLR4/MYD88 pathway." | 4.12 | Anethole's effects against myocardial infarction: The role of TLR4/NFκB and Nrf2/HO1 pathways. ( Mohamed, ME; Younis, NS, 2022) |
| " The present study aimed to investigate the effect of TQ on apoptotic parameters and MMP-9 expression in isoproterenol (ISP)-induced myocardial infarction (MI)." | 4.12 | Thymoquinone attenuates isoproterenol-induced myocardial infarction by inhibiting cytochrome C and matrix metalloproteinase-9 expression. ( Awad, A; Badr, AM; El-Bakly, WM; El-Demerdash, E; Medhet, M, 2022) |
| "In the present study, we assessed the therapeutic potential of Biochanin-A (BCA) (10 mg/kg BW/day) pretreatment for 30 days on lipid metabolic abnormalities, proinflammatory cytokines and matrix metalloproteinase expression in isoproterenol (ISO)-induced myocardial infarction (MI) in rats." | 4.12 | Attenuation of lipid metabolic abnormalities, proinflammatory cytokines, and matrix metalloproteinase expression by biochanin-A in isoproterenol-induced myocardial infarction in rats. ( Chandrasekaran, P; Jansy Isabella, RAR; Ponmurugan, P; Sangeethadevi, G; Saravanan, G; Sengottuvelu, S; V V, SU; Vadivukkarasi, S, 2022) |
| " The study was conducted to examine the ability of amniotic membrane mesenchymal stem cells (AMSCs) for protection against isoproterenol (ISO)-induced myocardial injury and attempted to show the possible mechanisms by which AMSCs that can be linked to inhibition of inflammation by targeting inflammatory MAPK/NF-κB pathway." | 4.12 | Human amniotic membrane mesenchymal stem cells exert cardioprotective effects against isoproterenol (ISO)-induced myocardial injury through suppression of inflammation and modulation of inflammatory MAPK/NF-κB pathway. ( Aboutaleb, N; Naseroleslami, M, 2022) |
| "Earlier studies reported that long-term treatment with thymoquinone (TQ) at a high dose (20 mg/kg) exerts a cardioprotective effect against isoproterenol (ISO)-triggered myocardial infarction (MI) in rats." | 4.12 | Thymoquinone Produces Cardioprotective Effect in β-Receptor Stimulated Myocardial Infarcted Rats via Subsiding Oxidative Stress and Inflammation. ( Agrawal, Y; Goyal, SN; Nagoor Meeran, MF; Nakhate, KT; Ojha, S; Patil, CR; Rathod, S; Sherikar, A, 2022) |
| "This study has explored the fact that geraniol prevents isoproterenol (ISO)-induced oxidative stress and inflammation-mediated myocardial infarction (MI) through enhanced expression of peroxiredoxin-1 (Prdx-1) in experimental animal models." | 4.12 | Geraniol enhances peroxiredoxin-1, and prevents isoproterenol-induced oxidative stress and inflammation associated with myocardial infarction in experimental animal models. ( Balupillai, A; David, E; Ranganathan, B; Saravanan, K; Wan, J; Zou, G, 2022) |
| " Rats were induced MI by isoproterenol (100 mg/kg body weight) and then treated with valencene and cardiac sensitive markers, cardiac hypertrophy, oxidative stress, markers of inflammation, nuclear factor- κB inflammatory pathway, and myocardial infarct size was estimated/determined." | 4.12 | Valencene post-treatment exhibits cardioprotection via inhibiting cardiac hypertrophy, oxidative stress, nuclear factor- κB inflammatory pathway, and myocardial infarct size in isoproterenol-induced myocardial infarcted rats; A molecular study. ( Berlin Grace, VM; Shervin Prince, S; Stanely Mainzen Prince, P, 2022) |
| "This study aimed to investigate the antihyperlipidemic and anti-inflammatory effect of zingiberene (ZBN) on isoproterenol-(ISO) induced myocardial infarction in rats." | 4.02 | Anti-inflammatory and anti-apoptotic effect of zingiberene on isoproterenol-induced myocardial infarction in experimental animals. ( Govindasamy, K; Li, J; Thangaiyan, R; Wei, J, 2021) |
| "As rats develop myocardial infarction (MI) like lesions when injected with large doses of isoproterenol (ISO), this investigation was designed to evaluate the dose-dependent effects of thymoquinone (TQ) on ISO-induced myocardial injury in rats." | 4.02 | Thymoquinone dose-dependently attenuates myocardial injury induced by isoproterenol in rats via integrated modulations of oxidative stress, inflammation, apoptosis, autophagy, and fibrosis. ( Elhadidy, WF; Farag, MM; Khalifa, AA; Rashad, RM, 2021) |
| "HC), a novel potent synthesized coumarin, on isoproterenol- (ISO-) induced myocardial infarction (MI) in rats." | 3.96 | (E)-N'-(1-(7-Hydroxy-2-Oxo-2H-Chromen-3-Yl) Ethylidene) Benzohydrazide, a Novel Synthesized Coumarin, Ameliorates Isoproterenol-Induced Myocardial Infarction in Rats through Attenuating Oxidative Stress, Inflammation, and Apoptosis. ( Abid, S; Allouche, N; Ammar, H; Elmufti, A; Feriani, A; Ghazouani, L; Hajji, R; Khdhiri, E; Mnafgui, K; Tir, M; Tlili, N, 2020) |
| " In the present study, we report that wogonin nanoparticles (Wog np) protect Isoproterenol (ISO) induced Myocardial Infarction (MI) rats." | 3.96 | Cardio protective role of wogonin loaded nanoparticle against isoproterenol induced myocardial infarction by moderating oxidative stress and inflammation. ( Bei, W; Chen, N; Jing, L, 2020) |
| " We have provided experimental evidence showing the suppressive effects of the nonselective β-adrenoreceptor antagonist propranolol on hyperglycemia, inflammation, and brain injury in a rat model experiencing cerebral ischemia." | 3.96 | Effects of β-Adrenergic Blockade on Metabolic and Inflammatory Responses in a Rat Model of Ischemic Stroke. ( Chang, CY; Chen, CJ; Chen, WY; Kuan, YH; Liao, SL; Lin, SY; Wang, YY; Wu, CC, 2020) |
| "We investigated the protective effect of tetramethylpyrazine (TMP) on injury related to acute myocardial ischemia (AMI) induced by isoproterenol (ISO)." | 3.91 | Tetramethylpyrazine exerts a protective effect against injury from acute myocardial ischemia by regulating the PI3K/Akt/GSK-3β signaling pathway. ( Chen, B; Huang, DD; Huang, HH; Li, DG; Yang, Q; Yuan, CL; Zhang, LM, 2019) |
| " The present study was directed to investigate the effect of ATV pre- and post-treatment in isoproterenol (ISO)-induced cardiotoxicity in rats." | 3.88 | Paradoxical effects of atorvastatin in isoproterenol-induced cardiotoxicity in rats: Role of oxidative stress and inflammation. ( Ahmed, LA; Attalla, DM; Khattab, MM; Zaki, HF, 2018) |
| " This study was performed to investigate the effects of syrigaldehyde (SYD), a phytochemical against isoproterenol (ISO) induced cardiotoxicity model." | 3.88 | Protective effect of syringaldehyde on biomolecular oxidation, inflammation and histopathological alterations in isoproterenol induced cardiotoxicity in rats. ( Akhtar, K; Mateen, S; Moin, S; Mubeena Mariyath, PM; Naeem, SS; Rizvi, W; Shahzad, S, 2018) |
| "The present study was designed to evaluate the cardioprotective potential of edaravone on oxidative stress, anti-apoptotic, anti-inflammatory and ultrastructure findings in isoproterenol (ISO) induced myocardial infarction (MI) in rats." | 3.81 | Edaravone protects rats against oxidative stress and apoptosis in experimentally induced myocardial infarction: Biochemical and ultrastructural evidence. ( Akhtar, M; Akhtar, MS; Ali, J; Haque, SE; Hassan, MQ; Najmi, AK, 2015) |
| " Our primary aim was to investigate βAR-mediated inflammation control (BARIC) responses of blood monocytes to isoproterenol (Iso) in relation to BP and CVD risk factors, including obesity, depressive mood, fasting glucose, triglycerides, and cholesterol levels in the 64 prehypertensive compared to 84 individuals with normal BP." | 3.81 | Beta-adrenergic receptor mediated inflammation control by monocytes is associated with blood pressure and risk factors for cardiovascular disease. ( Cheng, T; Dimitrov, S; Green, JM; Hong, S; Mills, PJ; Pruitt, C; Redwine, L; Shaikh, F; Wilson, K; Ziegler, MG, 2015) |
| " In this study, we investigated whether baicalin ameliorates isoproterenol-induced acute myocardial infarction and its mechanism." | 3.81 | Baicalin ameliorates isoproterenol-induced acute myocardial infarction through iNOS, inflammation and oxidative stress in rat. ( Chen, H; Ruan, H; Wang, J; Xu, Y; Zhao, W, 2015) |
| " Rehmannia complex (Reh) a famous prescription in China and the triterpene acids (TTA) isolated from Reh may relieve the isoproterenol (ISO) induced chronic inflammation in the brain, compared with APO." | 3.80 | Isoproterenol induced stressful reactions in the brain are characterized by inflammation due to activation of NADPH oxidase and ER stress: attenuated by Apocynin, Rehmannia complex and Triterpene acids. ( Cong, XD; Dai, DZ; Dai, Y; Du, RH; Li, Y; Mo, GL, 2014) |
| "We have previously shown that pentoxifylline (PTX) protects from vascular complications associated with insulin resistance (IR)." | 3.80 | Pentoxifylline alleviates cardiac ischemia and dysfunction following experimental angina in insulin resistance. ( Azhar, A; El-Bassossy, HM, 2014) |
| "Persistent β-adrenergic receptor stimulation with isoproterenol is associated with cardiac hypertrophy as well as cardiac synthesis of angiotensin II." | 3.78 | Spironolactone prevents alterations associated with cardiac hypertrophy produced by isoproterenol in rats: involvement of serum- and glucocorticoid-regulated kinase type 1. ( Ballesteros, S; Cachofeiro, V; Davel, AP; de las Heras, N; Lahera, V; Martín-Fernández, B; Miana, M; Rossoni, LV; Valero-Muñoz, M; Vassallo, D, 2012) |
| "To find a more excellent large-dose isoproterenol (ISO) induced heart failure (HF) rat model." | 3.76 | The study of ISO induced heart failure rat model. ( Feng, W; Li, W, 2010) |
| " We found that, in the left ventricle, Gal-3 1) enhanced macrophage and mast cell infiltration, increased cardiac interstitial and perivascular fibrosis, and causes cardiac hypertrophy; 2) increased TGF-beta expression and Smad3 phosphorylation; and 3) decreased negative change in pressure over time response to isoproterenol challenge, ratio of early left ventricular filling phase to atrial contraction phase, and left ventricular ejection fraction." | 3.75 | N-acetyl-seryl-aspartyl-lysyl-proline prevents cardiac remodeling and dysfunction induced by galectin-3, a mammalian adhesion/growth-regulatory lectin. ( André, S; Carretero, OA; D'Ambrosio, M; Gabius, HJ; Liao, TD; Liu, YH; Peng, H; Rhaleb, NE; Sharma, U, 2009) |
| "The results indicate that both Zafirlukast and Zileuton reduced the reported DCS symptoms, pulmonary edema, pleural and bronchoalveolar lavage protein levels, white blood cell counts in the pleural and bronchoalveolar lavage, and leukotriene levels in the bronchoalveolar lavage vs." | 3.74 | Pharmacological intervention to the inflammatory response from decompression sickness in rats. ( Butler, BD; Little, T, 2008) |
| "The influence of Isoproterenol on the number of the different types of white blood cells appearing during the course of the Sephadex inflammation was investigated in rats." | 3.66 | The influence of a permanent isoproterenol (ISO) application on the dynamics of the Sephadex inflammation. ( Egger, G; Porta, S, 1979) |
| "6-Shogaol pretreatment decreased the activities of cardiac and lipid peroxidative markers and enhanced the antioxidant status in ISO-induced cardiac injury rats." | 1.72 | 6-Shogaol protects against isoproterenol-induced cardiac injury in rats through attenutating oxidative stress, inflammation, apoptosis and activating nuclear respiratory factor-2/heme oxygenase-1 signaling pathway. ( Hu, L; Li, H; Luo, W; Shen, J; Zhang, Y, 2022) |
| "Visnagin (VIS) is a natural bioactive component of Ammi visnaga, with promising radical scavenging and anti-inflammatory activities." | 1.62 | Visnagin prevents isoproterenol-induced myocardial injury by attenuating oxidative stress and inflammation and upregulating Nrf2 signaling in rats. ( Abukhalil, MH; Al-Amarat, W; Al-Swailmi, FK; Aladaileh, SH; Alanazi, KM; Alfwuaires, MA; Algefare, AI; Althunibat, OY; Hussein, OE; Kamel, EM; Mahmoud, AM; Saghir, SA, 2021) |
| "Lycorine is an alkaloid with several beneficial biological properties." | 1.62 | Lycorine ameliorates isoproterenol-induced cardiac dysfunction mainly via inhibiting inflammation, fibrosis, oxidative stress and apoptosis. ( Fu, Y; Li, P; Wang, ZH; Wu, J; Wu, YX; Wu, ZX, 2021) |
| "Piperine pretreatment significantly prevented these changes in ISO treated group." | 1.56 | The protective effect of piperine against isoproterenol-induced inflammation in experimental models of myocardial toxicity. ( Aliev, G; Beeraka, NM; Chubarev, VN; Dhivya, V; Gavryushova, LV; Huang, CY; Mikhaleva, LM; Minyaeva, NN; Tarasov, VV; Viswanadha, VP, 2020) |
| " Wistar rats were dosed once with either isoproterenol (1." | 1.48 | miR-21-5p as a potential biomarker of inflammatory infiltration in the heart upon acute drug-induced cardiac injury in rats. ( De Ron, P; Fleming, A; Fleurance, R; Gryshkova, V; McGhan, P; Nogueira da Costa, A; Valentin, JP, 2018) |
| "Isoproterenol (ISO) has been widely used to establish cardiac injury in vivo and in vitro." | 1.46 | Shikonin ameliorates isoproterenol (ISO)-induced myocardial damage through suppressing fibrosis, inflammation, apoptosis and ER stress. ( Chen, DL; Wang, Z; Yang, J, 2017) |
| "Intrauterine inflammation is a major contributor to preterm birth and has adverse effects on preterm neonatal cardiovascular physiology." | 1.40 | Exposure to intrauterine inflammation leads to impaired function and altered structure in the preterm heart of fetal sheep. ( Barton, SK; Bensley, JG; Black, MJ; De Matteo, R; Gill, AW; Harding, R; Kim, MY; Kluckow, M; Lingwood, BE; Moss, TJ; Parkington, HC; Polglase, GR; Tare, M, 2014) |
| "Pretreatment with vanillic acid showed significant protective effects on cardiac troponins, lipid peroxidation, antioxidant system, electrocardiogram and expressions of interleukin-1β, interleukin-6 and tumor necrosis factor-α gene in the heart of isoproterenol induced cardiotoxic rats." | 1.37 | Protective effects of vanillic acid on electrocardiogram, lipid peroxidation, antioxidants, proinflammatory markers and histopathology in isoproterenol induced cardiotoxic rats. ( Dhanasekar, K; Rajakumar, S; Stanely Mainzen Prince, P, 2011) |
| "Pretreatment with ketamine caused a significant (P < 0." | 1.30 | Ketamine inhibits the proinflammatory cytokine-induced reduction of cardiac intracellular cAMP accumulation. ( Anderson, JL; Hill, GE; Lyden, ER, 1998) |
| "Isoproterenol could enhance the amplitude of this current once it developed." | 1.28 | Swelling-induced chloride-sensitive current in canine atrial cells revealed by whole-cell patch-clamp method. ( Sorota, S, 1992) |
| " Dexamethasone administration led to a sigmoidal dose-response curve in the case of alpha 2-APG whereas a biphasic sinusoidal-like dose-response curve was obtained for CRP." | 1.27 | Modulation of rat C-reactive protein serum level by dexamethasone and adrenaline--comparison with the response of alpha 2-acute phase globulin. ( Bürger, W; Göhler, K; Hirschelmann, R; Schade, R, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (15.13) | 18.7374 |
| 1990's | 4 (3.36) | 18.2507 |
| 2000's | 11 (9.24) | 29.6817 |
| 2010's | 44 (36.97) | 24.3611 |
| 2020's | 42 (35.29) | 2.80 |
| Authors | Studies |
|---|---|
| Abukhalil, MH | 3 |
| Hussein, OE | 1 |
| Aladaileh, SH | 3 |
| Althunibat, OY | 3 |
| Al-Amarat, W | 1 |
| Saghir, SA | 1 |
| Alfwuaires, MA | 2 |
| Algefare, AI | 2 |
| Alanazi, KM | 1 |
| Al-Swailmi, FK | 1 |
| Kamel, EM | 1 |
| Mahmoud, AM | 2 |
| Wu, J | 1 |
| Fu, Y | 4 |
| Wu, YX | 1 |
| Wu, ZX | 1 |
| Wang, ZH | 1 |
| Li, P | 1 |
| El-Shaer, NO | 1 |
| El Gazzar, WB | 1 |
| Allam, MM | 1 |
| Anwer, HM | 1 |
| Medhet, M | 1 |
| El-Bakly, WM | 2 |
| Badr, AM | 1 |
| Awad, A | 1 |
| El-Demerdash, E | 1 |
| Abduh, MS | 1 |
| Hanieh, H | 1 |
| Younis, NS | 2 |
| Mohamed, ME | 2 |
| Shervin Prince, S | 1 |
| Stanely Mainzen Prince, P | 2 |
| Berlin Grace, VM | 1 |
| Zou, G | 1 |
| Wan, J | 1 |
| Balupillai, A | 1 |
| David, E | 1 |
| Ranganathan, B | 1 |
| Saravanan, K | 1 |
| Rathod, S | 1 |
| Agrawal, Y | 1 |
| Sherikar, A | 1 |
| Nakhate, KT | 1 |
| Patil, CR | 1 |
| Nagoor Meeran, MF | 2 |
| Ojha, S | 2 |
| Goyal, SN | 1 |
| Lupu, M | 1 |
| Tudor, DV | 1 |
| Toma, VA | 1 |
| Florea, A | 1 |
| Lupsor, A | 1 |
| Moldovan, R | 1 |
| Stancu, B | 1 |
| Decea, N | 1 |
| Filip, AG | 1 |
| Liu, Z | 1 |
| Chen, X | 2 |
| Ye, T | 1 |
| Wan, W | 1 |
| Yu, Y | 1 |
| Zhang, C | 2 |
| Yang, B | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Allopurinol in the Treatment of Patients With Diabetes Mellitus and Multivessel Coronary Artery Disease Treated by Either PCI or CABG: Pilot Study[NCT03700645] | Phase 4 | 100 participants (Anticipated) | Interventional | 2018-12-01 | Not yet recruiting | ||
| Improving Blood Pressure and Cardiovascular Risk With Resistance Exercise in African Americans[NCT03016351] | 140 participants (Anticipated) | Interventional | 2016-10-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for isoproterenol and Inflammation
| Article | Year |
|---|---|
Nitric oxide and vascular reactivity in African American patients with hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Black or African American; Brachial Artery; Carba | 2003 |
Microvascular transport of macromolecules in normal and inflammatory conditions.
Topics: Animals; Biological Transport; Bradykinin; Capillaries; Capillary Permeability; Cricetinae; Dextrans | 1979 |
117 other studies available for isoproterenol and Inflammation
| Article | Year |
|---|---|
Visnagin prevents isoproterenol-induced myocardial injury by attenuating oxidative stress and inflammation and upregulating Nrf2 signaling in rats.
Topics: Adrenergic beta-Agonists; Animals; Inflammation; Isoproterenol; Khellin; Male; Myocardial Infarction | 2021 |
Lycorine ameliorates isoproterenol-induced cardiac dysfunction mainly via inhibiting inflammation, fibrosis, oxidative stress and apoptosis.
Topics: Amaryllidaceae Alkaloids; Animals; Apoptosis; Cytokines; Fibrosis; Heart; Heart Diseases; Inflammati | 2021 |
Ghrelin ameliorated inflammation and oxidative stress in isoproterenol induced myocardial infarction through the endothelial nitric oxide synthase (eNOS)/nuclear factor erythroid 2-related factor-2 (NRF2)/heme oxygenase-1 (HO-1) signaling pathway.
Topics: Animals; Ghrelin; Heme Oxygenase-1; Inflammation; Isoproterenol; Myocardial Infarction; Myocytes, Ca | 2021 |
Thymoquinone attenuates isoproterenol-induced myocardial infarction by inhibiting cytochrome C and matrix metalloproteinase-9 expression.
Topics: Animals; Apoptosis; Benzoquinones; Biomarkers; Cytochromes c; Gene Expression Regulation, Enzymologi | 2022 |
Umbelliferone prevents isoproterenol-induced myocardial injury by upregulating Nrf2/HO-1 signaling, and attenuating oxidative stress, inflammation, and cell death in rats.
Topics: Animals; Antioxidants; Cell Death; Inflammation; Isoproterenol; NF-E2-Related Factor 2; NF-kappa B; | 2022 |
Anethole's effects against myocardial infarction: The role of TLR4/NFκB and Nrf2/HO1 pathways.
Topics: Allylbenzene Derivatives; Animals; Anisoles; Antioxidants; Apoptosis; Heme Oxygenase-1; Inflammation | 2022 |
Valencene post-treatment exhibits cardioprotection via inhibiting cardiac hypertrophy, oxidative stress, nuclear factor- κB inflammatory pathway, and myocardial infarct size in isoproterenol-induced myocardial infarcted rats; A molecular study.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Body Weight; Cardiomegaly; Inflammation | 2022 |
Geraniol enhances peroxiredoxin-1, and prevents isoproterenol-induced oxidative stress and inflammation associated with myocardial infarction in experimental animal models.
Topics: Acyclic Monoterpenes; Animals; Antioxidants; Inflammation; Isoproterenol; Lipid Peroxidation; Lipid | 2022 |
Thymoquinone Produces Cardioprotective Effect in β-Receptor Stimulated Myocardial Infarcted Rats via Subsiding Oxidative Stress and Inflammation.
Topics: Animals; Benzoquinones; Cardiotonic Agents; Heart; Inflammation; Isoproterenol; Lipid Peroxidation; | 2022 |
Iron chelation effects on lipid peroxidation, inflammation and ventricular performance in a rat model of isoproterenol induced acute myocardial stress.
Topics: Animals; Inflammation; Iron; Iron Chelating Agents; Isoproterenol; Lipid Peroxidation; Male; Myocard | 2022 |
Pinocembrin alleviates the susceptibility to atrial fibrillation in isoproterenol-induced rats.
Topics: Animals; Atrial Fibrillation; Atrial Remodeling; Caspase 1; Collagen Type I; Connexins; Disease Mode | 2022 |
The protective effect of rivaroxaban with or without aspirin on inflammation, oxidative stress, and platelet reactivity in isoproterenol-induced cardiac injury in rats.
Topics: Animals; Aspirin; Biomarkers; Factor Xa Inhibitors; Heart Injuries; Inflammation; Isoproterenol; Mal | 2023 |
Cardioprotective Effect of Taxifolin against Isoproterenol-Induced Cardiac Injury through Decreasing Oxidative Stress, Inflammation, and Cell Death, and Activating Nrf2/HO-1 in Mice.
Topics: Antioxidants; Apoptosis; Heart Injuries; Humans; Inflammation; Isoproterenol; NF-E2-Related Factor 2 | 2022 |
Sophocarpine Alleviates Isoproterenol-Induced Kidney Injury by Suppressing Inflammation, Apoptosis, Oxidative Stress and Fibrosis.
Topics: Alkaloids; Animals; Apoptosis; Fibrosis; Inflammation; Isoproterenol; Kidney; Mice; NF-E2-Related Fa | 2022 |
Sophocarpine Alleviates Isoproterenol-Induced Kidney Injury by Suppressing Inflammation, Apoptosis, Oxidative Stress and Fibrosis.
Topics: Alkaloids; Animals; Apoptosis; Fibrosis; Inflammation; Isoproterenol; Kidney; Mice; NF-E2-Related Fa | 2022 |
Sophocarpine Alleviates Isoproterenol-Induced Kidney Injury by Suppressing Inflammation, Apoptosis, Oxidative Stress and Fibrosis.
Topics: Alkaloids; Animals; Apoptosis; Fibrosis; Inflammation; Isoproterenol; Kidney; Mice; NF-E2-Related Fa | 2022 |
Sophocarpine Alleviates Isoproterenol-Induced Kidney Injury by Suppressing Inflammation, Apoptosis, Oxidative Stress and Fibrosis.
Topics: Alkaloids; Animals; Apoptosis; Fibrosis; Inflammation; Isoproterenol; Kidney; Mice; NF-E2-Related Fa | 2022 |
Sophocarpine Alleviates Isoproterenol-Induced Kidney Injury by Suppressing Inflammation, Apoptosis, Oxidative Stress and Fibrosis.
Topics: Alkaloids; Animals; Apoptosis; Fibrosis; Inflammation; Isoproterenol; Kidney; Mice; NF-E2-Related Fa | 2022 |
Sophocarpine Alleviates Isoproterenol-Induced Kidney Injury by Suppressing Inflammation, Apoptosis, Oxidative Stress and Fibrosis.
Topics: Alkaloids; Animals; Apoptosis; Fibrosis; Inflammation; Isoproterenol; Kidney; Mice; NF-E2-Related Fa | 2022 |
Sophocarpine Alleviates Isoproterenol-Induced Kidney Injury by Suppressing Inflammation, Apoptosis, Oxidative Stress and Fibrosis.
Topics: Alkaloids; Animals; Apoptosis; Fibrosis; Inflammation; Isoproterenol; Kidney; Mice; NF-E2-Related Fa | 2022 |
Sophocarpine Alleviates Isoproterenol-Induced Kidney Injury by Suppressing Inflammation, Apoptosis, Oxidative Stress and Fibrosis.
Topics: Alkaloids; Animals; Apoptosis; Fibrosis; Inflammation; Isoproterenol; Kidney; Mice; NF-E2-Related Fa | 2022 |
Sophocarpine Alleviates Isoproterenol-Induced Kidney Injury by Suppressing Inflammation, Apoptosis, Oxidative Stress and Fibrosis.
Topics: Alkaloids; Animals; Apoptosis; Fibrosis; Inflammation; Isoproterenol; Kidney; Mice; NF-E2-Related Fa | 2022 |
Toll-like receptor-2 in cardiomyocytes and macrophages mediates isoproterenol-induced cardiac inflammation and remodeling.
Topics: Adaptor Proteins, Signal Transducing; Animals; Arrhythmias, Cardiac; Heart Failure; Inflammation; Is | 2023 |
β2AR against myocarditis-lipid deposition depends on estrogenic environment in stress.
Topics: Animals; Anti-Inflammatory Agents; Estrogens; Inflammasomes; Inflammation; Isoproterenol; Lipids; Mi | 2023 |
Vanillin and pentoxifylline ameliorate isoproterenol-induced myocardial injury in rats
Topics: Animals; Inflammation; Isoproterenol; Myocardial Infarction; Myocardium; Oxidative Stress; Pentoxify | 2023 |
Biochanin-A alleviates fibrosis and inflammation in cardiac injury in mice.
Topics: Animals; Collagen; Collagen Type I; Fibrosis; Heart Injuries; Inflammation; Isoproterenol; Lipids; M | 2023 |
6-Shogaol protects against isoproterenol-induced cardiac injury in rats through attenutating oxidative stress, inflammation, apoptosis and activating nuclear respiratory factor-2/heme oxygenase-1 signaling pathway.
Topics: Animals; Antioxidants; Apoptosis; Catechols; Creatine Kinase; GA-Binding Protein Transcription Facto | 2022 |
Exercise Training Attenuates Acute β-Adrenergic Receptor Activation-Induced Cardiac Inflammation via the Activation of AMP-Activated Protein Kinase.
Topics: Adrenergic beta-Agonists; AMP-Activated Protein Kinases; Animals; Arrhythmias, Cardiac; Exercise; In | 2023 |
Cardioprotective effects of Schisantherin A against isoproterenol-induced acute myocardial infarction through amelioration of oxidative stress and inflammation via modulation of PI3K-AKT/Nrf2/ARE and TLR4/MAPK/NF-κB pathways in rats.
Topics: Animals; Body Weight; Inflammation; Isoproterenol; Myocardial Infarction; NF-E2-Related Factor 2; NF | 2023 |
Anti-inflammatory, cardioprotective effect of gypenoside against isoproterenol-induced cardiac remodeling in rats via alteration of inflammation and gut microbiota.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Cytokines; Gastrointestinal Microbiome; | 2023 |
Punicalagin attenuates myocardial oxidative damage, inflammation, and apoptosis in isoproterenol-induced myocardial infarction in rats: Biochemical, immunohistochemical, and in silico molecular docking studies.
Topics: Animals; Antioxidants; Apoptosis; Cytokines; Hydrolyzable Tannins; Inflammation; Isoproterenol; Mole | 2023 |
CP-25 inhibits the hyperactivation of rheumatic synoviocytes by suppressing the switch in G
Topics: Animals; Arthritis, Experimental; Cell Proliferation; Cells, Cultured; Epinephrine; Fibroblasts; Inf | 2023 |
Cardio protective role of wogonin loaded nanoparticle against isoproterenol induced myocardial infarction by moderating oxidative stress and inflammation.
Topics: Animals; Antioxidants; Biomarkers; Cardiotonic Agents; Cytokines; Drug Liberation; Flavanones; Heme | 2020 |
(E)-N'-(1-(7-Hydroxy-2-Oxo-2H-Chromen-3-Yl) Ethylidene) Benzohydrazide, a Novel Synthesized Coumarin, Ameliorates Isoproterenol-Induced Myocardial Infarction in Rats through Attenuating Oxidative Stress, Inflammation, and Apoptosis.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Benzopyrans; Biomarkers; Coumarins; Hydrazones; Inflam | 2020 |
Gentianella acuta prevents acute myocardial infarction induced by isoproterenol in rats via inhibition of galectin-3/TLR4/MyD88/NF-кB inflammatory signalling.
Topics: Animals; Apoptosis; Cardiotonic Agents; Cytokines; Galectin 3; Gentianella; Inflammation; Isoprotere | 2021 |
Effects of β-Adrenergic Blockade on Metabolic and Inflammatory Responses in a Rat Model of Ischemic Stroke.
Topics: Adrenergic beta-Antagonists; Animals; Brain Injuries; Cell Line; Cytokines; Disease Models, Animal; | 2020 |
Canagliflozin attenuates isoprenaline-induced cardiac oxidative stress by stimulating multiple antioxidant and anti-inflammatory signaling pathways.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Canagliflozin; Disease Models, Animal; H | 2020 |
The protective effect of piperine against isoproterenol-induced inflammation in experimental models of myocardial toxicity.
Topics: Adrenergic beta-Agonists; Alkaloids; Animals; Benzodioxoles; Cardiomegaly; Cytokines; Endothelium; F | 2020 |
Canagliflozin ameliorates renal oxidative stress and inflammation by stimulating AMPK-Akt-eNOS pathway in the isoprenaline-induced oxidative stress model.
Topics: AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Antioxidants; Canagliflozin; Cells | 2020 |
α-Galactosylceramide and its analog OCH differentially affect the pathogenesis of ISO-induced cardiac injury in mice.
Topics: Animals; Cardiomegaly; Cardiotonic Agents; Cytokines; Fibrosis; Galactosylceramides; Glycolipids; In | 2020 |
Membrane nanotubes facilitate the propagation of inflammatory injury in the heart upon overactivation of the β-adrenergic receptor.
Topics: Adrenergic beta-Agonists; Animals; Animals, Newborn; Cell Membrane; Fibroblasts; Heart; Inflammation | 2020 |
Anti-inflammatory and anti-apoptotic effect of zingiberene on isoproterenol-induced myocardial infarction in experimental animals.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Humans; Inflammation; Isoproterenol; Male; Models, Ani | 2021 |
Appearance of Heterogeneous Macrophages During Development of Isoproterenol-Induced Rat Myocardial Fibrosis.
Topics: Animals; Fibrosis; Inflammation; Isoproterenol; Macrophages; Rats; Rats, Inbred F344 | 2021 |
Protective effects of myrrh essential oil on isoproterenol-induced myocardial infarction in rats through antioxidant, anti-inflammatory, Nrf2/HO-1 and apoptotic pathways.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Biomarkers; Blood Pressure; Cardiotonic | 2021 |
Pinoresinol diglucoside (PDG) attenuates cardiac hypertrophy via AKT/mTOR/NF-κB signaling in pressure overload-induced rats.
Topics: Animals; Animals, Newborn; Aorta, Abdominal; Cardiomegaly; Constriction, Pathologic; Disease Models, | 2021 |
Nootkatone attenuates myocardial oxidative damage, inflammation, and apoptosis in isoproterenol-induced myocardial infarction in rats.
Topics: Animals; Apoptosis; Heart; Inflammation; Isoproterenol; Male; Myocardial Infarction; Myocardium; Oxi | 2021 |
Attenuation of lipid metabolic abnormalities, proinflammatory cytokines, and matrix metalloproteinase expression by biochanin-A in isoproterenol-induced myocardial infarction in rats.
Topics: Animals; Cytokines; Inflammation; Interleukin-6; Isoproterenol; Lipids; Matrix Metalloproteinase 2; | 2022 |
Human amniotic membrane mesenchymal stem cells exert cardioprotective effects against isoproterenol (ISO)-induced myocardial injury through suppression of inflammation and modulation of inflammatory MAPK/NF-κB pathway.
Topics: Amnion; Humans; Inflammation; Isoproterenol; Mesenchymal Stem Cells; Myocardial Infarction; NF-kappa | 2022 |
Thymoquinone dose-dependently attenuates myocardial injury induced by isoproterenol in rats via integrated modulations of oxidative stress, inflammation, apoptosis, autophagy, and fibrosis.
Topics: Animals; Antioxidants; Apoptosis; Autophagy; Benzoquinones; Cardiotonic Agents; Disease Progression; | 2021 |
Glibenclamide alleviates β adrenergic receptor activation-induced cardiac inflammation.
Topics: Animals; Arrhythmias, Cardiac; Glyburide; Inflammasomes; Inflammation; Isoproterenol; Male; Mice; Mi | 2022 |
IL-18 cleavage triggers cardiac inflammation and fibrosis upon β-adrenergic insult.
Topics: Adrenergic beta-Agonists; Animals; Cytokines; Fibrosis; Heart; Humans; Inflammasomes; Inflammation; | 2018 |
Shikonin ameliorates isoproterenol (ISO)-induced myocardial damage through suppressing fibrosis, inflammation, apoptosis and ER stress.
Topics: Animals; Apoptosis; Cardiomyopathies; Caspase 3; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Re | 2017 |
Nepeta deflersiana attenuates isoproterenol-induced myocardial injuries in rats: Possible involvement of oxidative stress, apoptosis, inflammation through nuclear factor (NF)-κB downregulation.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Caspase 3; Cytokines; Down-Regulation; H | 2017 |
miR-21-5p as a potential biomarker of inflammatory infiltration in the heart upon acute drug-induced cardiac injury in rats.
Topics: Allylamine; Animals; Cardiotoxicity; Disease Models, Animal; Gene Expression Profiling; Gene Express | 2018 |
Paradoxical effects of atorvastatin in isoproterenol-induced cardiotoxicity in rats: Role of oxidative stress and inflammation.
Topics: Animals; Antioxidants; Atorvastatin; Biomarkers; Cardiotonic Agents; Cardiotoxicity; Heart; Inflamma | 2018 |
Pitavastatin ameliorates myocardial damage by preventing inflammation and collagen deposition via reduced free radical generation in isoproterenol-induced cardiomyopathy.
Topics: Animals; Antioxidants; Aspartate Aminotransferases; Catalase; Collagen; Creatine Kinase, MB Form; Fr | 2019 |
Protective effect of syringaldehyde on biomolecular oxidation, inflammation and histopathological alterations in isoproterenol induced cardiotoxicity in rats.
Topics: Adenosine Triphosphatases; Animals; Antioxidants; Benzaldehydes; Biomarkers; Cardiotoxicity; Erythro | 2018 |
Mechanistic insights to the cardioprotective effect of blueberry nutraceutical extract in isoprenaline-induced cardiac hypertrophy.
Topics: Animals; Blueberry Plants; Cardiomegaly; Cardiotonic Agents; Catalase; Dietary Supplements; Fibrosis | 2018 |
Beta Adrenergic Receptors Stimulation Attenuates Phosphorylation of NF-κB and IκBα in Hyperglycemic Endothelial Cells.
Topics: Adrenergic beta-Agonists; Apoptosis; Endothelial Cells; Human Umbilical Vein Endothelial Cells; Huma | 2018 |
Adipocyte Death Preferentially Induces Liver Injury and Inflammation Through the Activation of Chemokine (C-C Motif) Receptor 2-Positive Macrophages and Lipolysis.
Topics: Adipocytes; Adipose Tissue; Animals; Bacteriocins; Cell Death; Disease Models, Animal; Epinephrine; | 2019 |
Tetramethylpyrazine exerts a protective effect against injury from acute myocardial ischemia by regulating the PI3K/Akt/GSK-3β signaling pathway.
Topics: Animals; Cytokines; Glycogen Synthase Kinase 3 beta; Inflammation; Isoproterenol; Male; Myocardial I | 2019 |
Dipeptidyl peptidase-4 inhibition prevents vascular dysfunction induced by β-adrenergic hyperactivity.
Topics: Adrenergic beta-Agonists; Animals; Cytokines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibi | 2019 |
Enhanced Keap1-Nrf2 signaling protects the myocardium from isoproterenol-induced pathological remodeling in mice.
Topics: Animals; Antioxidants; Biomarkers; Glutathione; Heart; Inflammation; Isoproterenol; Kelch-Like ECH-A | 2019 |
Fibroblast growth factor 21 protects against cardiac hypertrophy in mice.
Topics: Animals; Animals, Newborn; Cardiomegaly; Cardiotonic Agents; Fetus; Fibroblast Growth Factors; Gene | 2013 |
The Fas/FasL pathway impairs the alveolar fluid clearance in mouse lungs.
Topics: Acute Lung Injury; Adenoma; Adrenergic beta-Agonists; Animals; Apoptosis; Bronchoalveolar Lavage Flu | 2013 |
Citrus medica "Otroj": attenuates oxidative stress and cardiac dysrhythmia in isoproterenol-induced cardiomyopathy in rats.
Topics: Animals; Antioxidants; Biomarkers; Biphenyl Compounds; Cardiomyopathies; Citrus; Female; Flavonoids; | 2013 |
Preventive effects of selenium yeast, chromium picolinate, zinc sulfate and their combination on oxidative stress, inflammation, impaired angiogenesis and atherogenesis in myocardial infarction in rats.
Topics: Animals; Atherosclerosis; Cardiotonic Agents; Drug Therapy, Combination; Dyslipidemias; Inflammation | 2013 |
Isoproterenol induced stressful reactions in the brain are characterized by inflammation due to activation of NADPH oxidase and ER stress: attenuated by Apocynin, Rehmannia complex and Triterpene acids.
Topics: Acetophenones; Animals; Brain; Cells, Cultured; Endoplasmic Reticulum Stress; Enzyme Activation; Inf | 2014 |
Activation of pattern recognition receptors in brown adipocytes induces inflammation and suppresses uncoupling protein 1 expression and mitochondrial respiration.
Topics: Adipocytes; Adipose Tissue, Brown; Animals; Cell Line; Cytokines; Diet, High-Fat; Electron Transport | 2014 |
Exposure to intrauterine inflammation leads to impaired function and altered structure in the preterm heart of fetal sheep.
Topics: Adrenergic beta-Agonists; Animals; Female; Fetal Heart; Gene Expression Regulation, Developmental; H | 2014 |
Pentoxifylline alleviates cardiac ischemia and dysfunction following experimental angina in insulin resistance.
Topics: Adiponectin; Administration, Oral; Angina Pectoris; Animals; Diet; Disease Models, Animal; Electroca | 2014 |
Pre-treatment with α-tocopherol and Terminalia arjuna ameliorates, pro-inflammatory cytokines, cardiac and apoptotic markers in myocardial infracted rats.
Topics: alpha-Tocopherol; Animals; Apoptosis; bcl-2-Associated X Protein; Cardiotonic Agents; Chromatography | 2015 |
Thymol attenuates inflammation in isoproterenol induced myocardial infarcted rats by inhibiting the release of lysosomal enzymes and downregulating the expressions of proinflammatory cytokines.
Topics: Animals; Anti-Inflammatory Agents; C-Reactive Protein; Cytokines; Down-Regulation; Electrocardiograp | 2015 |
Xanthine oxidase inhibition alleviates the cardiac complications of insulin resistance: effect on low grade inflammation and the angiotensin system.
Topics: Administration, Oral; Allopurinol; Angiotensin II; Animals; Diet, High-Fat; Electrocardiography; Enz | 2015 |
Edaravone protects rats against oxidative stress and apoptosis in experimentally induced myocardial infarction: Biochemical and ultrastructural evidence.
Topics: Animals; Antioxidants; Antipyrine; Apoptosis; C-Reactive Protein; Caspase 3; Creatine Kinase, MB For | 2015 |
Beta-adrenergic receptor mediated inflammation control by monocytes is associated with blood pressure and risk factors for cardiovascular disease.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Aged; Blood Glucose; Blood Pressure; Cardiovascular Dis | 2015 |
Selective TNF-α targeting with infliximab attenuates impaired oxygen metabolism and contractile function induced by an acute exposure to air particulate matter.
Topics: Adrenergic beta-Agonists; Animals; Antirheumatic Agents; Coal Ash; Female; Heart; Heart Ventricles; | 2015 |
Baicalin ameliorates isoproterenol-induced acute myocardial infarction through iNOS, inflammation and oxidative stress in rat.
Topics: Animals; Apoptosis; Casein Kinases; Caspase 3; Creatine Kinase, MB Form; Enzyme Inhibitors; Flavonoi | 2015 |
Amelioration of inflammation by phenolic rich methanolic extract of Ocimum sanctum Linn. leaves in isoproterenol induced myocardial infarction.
Topics: Animals; Antioxidants; Disease Models, Animal; Inflammation; Isoproterenol; Leukotriene B4; Male; Me | 2015 |
'Ajwa' dates (Phoenix dactylifera L.) extract ameliorates isoproterenol-induced cardiomyopathy through downregulation of oxidative, inflammatory and apoptotic molecules in rodent model.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Cardiomyopathies; Cardiotonic Agents; Do | 2016 |
Dual Effect of Catecholamines and Corticosterone Crosstalk on Pineal Gland Melatonin Synthesis.
Topics: Adrenergic beta-Agonists; Animals; Catecholamines; Corticosterone; Inflammation; Isoproterenol; Lipo | 2017 |
Maternal inflammation activated ROS-p38 MAPK predisposes offspring to heart damages caused by isoproterenol via augmenting ROS generation.
Topics: Animals; Antioxidants; Female; Heart; Heart Diseases; Imidazoles; Inflammation; Isoproterenol; Male; | 2016 |
Bilateral Renal Denervation Ameliorates Isoproterenol-Induced Heart Failure through Downregulation of the Brain Renin-Angiotensin System and Inflammation in Rat.
Topics: Animals; Brain; Denervation; Down-Regulation; Heart Failure; Inflammation; Isoproterenol; Kidney; Ma | 2016 |
Inflammation and exercise: Inhibition of monocytic intracellular TNF production by acute exercise via β
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adult; Cytokines; Epinephrine; Exercise; Female | 2017 |
N-acetyl-seryl-aspartyl-lysyl-proline prevents cardiac remodeling and dysfunction induced by galectin-3, a mammalian adhesion/growth-regulatory lectin.
Topics: Animals; Anti-Inflammatory Agents; Blood Pressure; Body Weight; Cardiac Output; Cardiomegaly; Cardio | 2009 |
Qualification of cardiac troponin I concentration in mouse serum using isoproterenol and implementation in pharmacology studies to accelerate drug development.
Topics: Animals; Aspartate Aminotransferases; Biomarkers; Cardiotonic Agents; Creatine Kinase; Dose-Response | 2009 |
The study of ISO induced heart failure rat model.
Topics: Animals; Echocardiography; Endomyocardial Fibrosis; Heart Failure; Immunohistochemistry; Inflammatio | 2010 |
Exercise training inhibits inflammatory cytokines and more than prevents myocardial dysfunction in rats with sustained beta-adrenergic hyperactivity.
Topics: Adrenergic beta-Agonists; Animals; Blotting, Western; Cardiomegaly; Cardiomyopathies; Cardiotonic Ag | 2010 |
Metformin counters both lipolytic/inflammatory agents-decreased hormone sensitive lipase phosphorylation at Ser-554 and -induced lipolysis in human adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adipocytes; Adult; Aged; Colforsin; Female; Humans; Hypoglycemic Agents | 2011 |
Increased adipose tissue oxygen tension in obese compared with lean men is accompanied by insulin resistance, impaired adipose tissue capillarization, and inflammation.
Topics: Adipose Tissue; Angiotensin II; Humans; Hyperoxia; Inflammation; Insulin Resistance; Isoproterenol; | 2011 |
Protective effects of vanillic acid on electrocardiogram, lipid peroxidation, antioxidants, proinflammatory markers and histopathology in isoproterenol induced cardiotoxic rats.
Topics: Animals; Biomarkers; Cardiotoxins; Cytokines; Electrocardiography; Free Radical Scavengers; Gene Exp | 2011 |
Influence of influenza A infection on capsaicin-induced responses in murine airways.
Topics: Animals; Biphenyl Compounds; Bronchoalveolar Lavage Fluid; Capsaicin; Carbachol; Cyclooxygenase Inhi | 2012 |
p53-induced adipose tissue inflammation is critically involved in the development of insulin resistance in heart failure.
Topics: Adipose Tissue; Animals; Cell Line; Heart Failure; Humans; Inflammation; Insulin Resistance; Isoprot | 2012 |
Spironolactone prevents alterations associated with cardiac hypertrophy produced by isoproterenol in rats: involvement of serum- and glucocorticoid-regulated kinase type 1.
Topics: Aldosterone; Animals; Blood Pressure; Cardiomegaly; Fibrosis; Heart; Immediate-Early Proteins; Infla | 2012 |
Association of in vivo β-adrenergic receptor sensitivity with inflammatory markers in healthy subjects.
Topics: Adrenergic beta-Agonists; Adult; Animals; Biomarkers; C-Reactive Protein; Cross-Sectional Studies; F | 2012 |
The function of calcineurin and ERK1/2 signal in the antihypertrophic effects of kappa-opioid receptor stimulation on myocardial hypertrophy induced by isoprenaline.
Topics: Adrenergic beta-Agonists; Animals; Blotting, Western; Calcineurin; Calcium Signaling; Cardiomegaly; | 2012 |
SYMPATHOMIMETIC AMINES AND VASCULAR PERMEABILITY.
Topics: Anti-Inflammatory Agents; Capillary Permeability; Dextrans; Epinephrine; Inflammation; Isoproterenol | 1965 |
Effects of in vivo treatment with interleukins 1beta and 6 on rat mesenteric vascular bed reactivity.
Topics: Acetylcholine; Animals; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Syn | 2003 |
Protein associated with Myc (PAM) is involved in spinal nociceptive processing.
Topics: Adaptor Proteins, Signal Transducing; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Animals, | 2004 |
Rapamycin inhibits release of tumor necrosis factor-alpha from human vascular smooth muscle cells.
Topics: Analysis of Variance; Anti-Bacterial Agents; Causality; Cell Division; Cell Movement; Cells, Culture | 2004 |
Sympathoadrenal-dependent sexually dimorphic effect of nonhabituating stress on in vivo neutrophil recruitment in the rat.
Topics: Acoustic Stimulation; Adrenal Glands; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals | 2005 |
Aristolochic Acid induces heart failure in zebrafish embryos that is mediated by inflammation.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aristolochic Acids; Cyclooxygenase 2; Cyclooxygen | 2007 |
Reduction of plasma sCD40L and stimulated MIP-1-alpha production by in vivo beta-adrenergic stimulation.
Topics: Adipose Tissue; Adrenergic beta-Agonists; Adult; Biomarkers; CD40 Ligand; Chemokine CCL3; Down-Regul | 2007 |
Tonic beta-adrenergic drive provokes proinflammatory and proapoptotic changes in aging mouse heart.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Amidines; Animals; Apoptosis; Benzylam | 2008 |
Pharmacological intervention to the inflammatory response from decompression sickness in rats.
Topics: Animals; Cyclooxygenase Inhibitors; Decompression Sickness; Hydroxyurea; Indoles; Indomethacin; Infl | 2008 |
Cyclic nucleotides in immune responses and allergy.
Topics: Adenosine; Animals; Antigens; Basophils; Cyclic AMP; Histamine Release; Humans; Hypersensitivity, Im | 1980 |
Modifications in the regression of the acute inflammation caused by a beta-adrenergic effect unbalanced by the alpha-component ("biased beta-effect").
Topics: Animals; Catecholamines; Cell Movement; Dextrans; Inflammation; Isoproterenol; Lymphocytes; Male; Ph | 1982 |
The long-term influence of isoproterenol (ISO) retard tablets on the course of an acute inflammation.
Topics: Acute Disease; Animals; Body Weight; Delayed-Action Preparations; Dextrans; Heart; Inflammation; Iso | 1984 |
In vivo demonstration of endogenous substances regulating the regression of the acute inflammation.
Topics: Acute Disease; Animals; Cell Movement; Eosinophils; Epinephrine; Inflammation; Isoproterenol; Leukoc | 1981 |
Ketamine inhibits the proinflammatory cytokine-induced reduction of cardiac intracellular cAMP accumulation.
Topics: Adrenergic beta-Agonists; Anesthetics, Dissociative; Animals; Cell Line; Colforsin; Cyclic AMP; Cyto | 1998 |
Effects of neurotransmitters, gut hormones, and inflammatory mediators on mucus discharge in rat colon.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Atropine; Bethanechol; Bombesin; Calcitonin Gene-Related Pe | 1998 |
Opposite effects of interferon-gamma and prostaglandin E2 on tumor necrosis factor and interleukin-10 production in microglia: a regulatory loop controlling microglia pro- and anti-inflammatory activities.
Topics: Animals; Animals, Newborn; Cells, Cultured; Cytokines; Dinoprostone; Gene Expression Regulation; Inf | 1999 |
The influence of a permanent isoproterenol (ISO) application on the dynamics of the Sephadex inflammation.
Topics: Animals; Cell Movement; Dextrans; Eosinophils; Inflammation; Isoproterenol; Leukocytes; Lymphocytes; | 1979 |
Antiinflammatory substances appearing during an acute inflammation and the alteration of their properties by isoproterenol (ISO). An in vivo investigation in rats.
Topics: Animals; Cell Count; Cell Movement; Eosinophils; Inflammation; Isoproterenol; Lymphocytes; Male; Mon | 1979 |
Morphological changes observed after stimulation or inhibition of adrenic system in rats chronically treated with hydrazinophtalazines.
Topics: Animals; Catecholamines; Epinephrine; Heart; Heart Diseases; Hemorrhage; Hydralazine; Inflammation; | 1979 |
Swelling-induced chloride-sensitive current in canine atrial cells revealed by whole-cell patch-clamp method.
Topics: Animals; Atrial Function; Chlorides; Cytological Techniques; Dogs; Electrophysiology; Heart Atria; I | 1992 |
Modulation of rat C-reactive protein serum level by dexamethasone and adrenaline--comparison with the response of alpha 2-acute phase globulin.
Topics: alpha-Macroglobulins; Animals; Arthritis, Experimental; C-Reactive Protein; Circadian Rhythm; Dexame | 1987 |
Antigen challenge modifies the cyclic AMP response of inflammatory mediators and beta-adrenergic drugs in alveolar macrophages.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Antigens; Bronchoalveolar | 1989 |
Mechanism of antianaphylactic action of beta-agonists in allergic inflammation of air pouch type in rats.
Topics: Adrenergic beta-Antagonists; Anaphylaxis; Animals; Antibodies, Anti-Idiotypic; Capillary Permeabilit | 1987 |
Intestinal iron absorption during turpentine sterile inflammation in the rat. Influences of isoproterenol and propranolol.
Topics: Animals; Female; Inflammation; Intestinal Absorption; Iron; Isoproterenol; Liver; Propranolol; Rats; | 1987 |
Comparative effects of non-steroidal anti-inflammatory drugs, mefenamic acid, metiazinic acid and glucametacin on the inflammatory response induced by subcutaneous implantation of human dental plaque and on the mitotic activity of isoproterenol-stimulated
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dental Plaque; Female; Humans; Indomethacin; Infla | 1986 |
Leukocytes as secretory organs of inflammation.
Topics: Atropine; Blood Platelets; Bucladesine; Carbachol; Cell Survival; Cells, Cultured; Colchicine; Cycli | 1973 |
Mechanism of the pro-inflammatory activity of sympathomimetic amines in thermic oedema of the rat paw.
Topics: Animals; Blood Circulation; Bradykinin; Capillary Permeability; Edema; Epinephrine; Foot; Heparin; H | 1974 |
[Myocardial lesions induced by isoprenaline and their prevention by cinnarizine].
Topics: Animals; Cinnamates; Female; Inflammation; Injections, Subcutaneous; Isoproterenol; Myocardium; Necr | 1972 |
Study on the idiopathic cardiomyopathy. Diagnostic value of the apexcardiogram, 131 Cs scintiscanning of the heart and plasma hydroxyproline.
Topics: Adult; Amyl Nitrite; Autopsy; Cardiomyopathies; Cesium Isotopes; Child; Collagen; Collagen Diseases; | 1971 |