Page last updated: 2024-10-29

isoproterenol and Hypoxia

isoproterenol has been researched along with Hypoxia in 303 studies

Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.

Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.

Research Excerpts

ExcerptRelevanceReference
"Isoproterenol and hypoxemia-hypercapnia will increase myocardial oxygen demand and could prove to be detrimental in severe asthma."9.07The effect of hypercapnia and hypoxemia on the cardiovascular responses to isoproterenol. ( Beasley, R; Bremner, P; Buckly, D; Burgess, C; Crane, J; Galletly, D; McHaffie, D; Purdie, G; Robinson, B, 1994)
"The dynamics of the changes in myocardial phosphorylated compound contents (inorganic phosphate: Pi; phosphocreatine: PCr; ATP) induced by 10(-6)M isoprenaline administration was studied, using 31P-NMR spectroscopy, in hearts isolated from rats adapted for three weeks to normobaric hypoxia (10% of oxygen)."7.69Adaptation to chronic hypoxia alters cardiac metabolic response to beta stimulation: novel face of phosphocreatine overshoot phenomenon. ( Aussedat, J; Novel-Chaté, V; Rossi, A; Saks, VA, 1995)
"The role of adenosine in hypoxia-induced vasodilation was examined in the intestine of pentobarbital sodium-anesthetized cats."7.68Hypoxia-induced vasodilation of the feline superior mesenteric artery is not adenosine mediated. ( Lautt, WW; Lockhart, LK, 1990)
"The hypothesis of a blunted chronotropic response of cardiac beta-adrenergic receptors in altitude hypoxia was tested in nine subjects at sea level (SL) by infusion of isoproterenol."7.67Decreased cardiac response to isoproterenol infusion in acute and chronic hypoxia. ( Baud, P; Kéromès, A; Larmignat, P; Lhoste, F; Rathat, C; Richalet, JP, 1988)
"A decrease in heart rate response to isoproterenol (IP) infusion has been previously described in humans exposed to acute (2-3 days) or chronic (21 days) exposure to altitude hypoxia (J."7.67Reversal of hypoxia-induced decrease in human cardiac response to isoproterenol infusion. ( Bouissou, P; Keromes, A; Le-Trong, JL; Merlet, P; Rathat, C; Richalet, JP; Veyrac, P, 1989)
"A hemodynamic study with blood gas analysis was performed so we could observe changes induced by blood volume expansion, dopamine infusion and isoproterenol infusion in 20 adult patients suffering from peritonitis complicated with septic shock and acute respiratory failure."7.66Venous admixture in human septic shock: comparative effects of blood volume expansion, dopamine infusion and isoproterenol infusion on mismatching of ventilation and pulmonary blood flow in peritonitis. ( Delille, F; Eveleigh, MC; Gurdjian, F; Jardin, F; Margairaz, A, 1979)
"Some circulatory effects of thoracic epidural analgesia (TEA) were investigated in splenectomized, open-chest sheep during normoxia, hypoxia and isoproterenol administration."7.66Cardiovascular effects of epidural analgesia. I. Thoracic epidural analgesia. An experimental study in sheep of the effects on central circulation, regional perfusion and myocardial performance during normoxia, hypoxia and isoproterenol administration. ( Jynge, P; Ottesen, S; Renck, H, 1978)
"6 km/h), we studied the effect of ozone on ventilatory responses to hypercapnia and to hypoxia."7.66Mechanism of ozone-induced tachypneic response to hypoxia and hypercapnia in conscious dogs. ( Djokic, TD; Dumont, C; Graf, PD; Lee, LY; Nadel, JA, 1980)
"Myocardial necrosis was induced in male Wistar rats by isoproterenol as described by Rona et al."7.66Hypoxic tolerance of rats with isoproterenol-induced myocardial necrosis. ( Bhatia, B; Datta, K; Nijhawan, R, 1980)
" This is true for systemic hypoxia, hemorrhagic shock, and isoproterenol infusion."7.65Transmural metabolic gradients of the canine left ventricle in coronary constriction, systemic hypoxia, hemorrhagic shock, and isoproterenol infusion. ( Leunissen, RL, 1975)
"Forty-five normotensive and hypertensive sleep apnea patients (respiratory disturbance index >20) and non-apneic controls."5.30The effects of hypoxia and sleep apnea on isoproterenol sensitivity. ( Ancoli-Israel, S; Clausen, J; Dimsdale, JE; Loredo, JS; Mills, PJ, 1998)
"Isoproterenol and hypoxemia-hypercapnia will increase myocardial oxygen demand and could prove to be detrimental in severe asthma."5.07The effect of hypercapnia and hypoxemia on the cardiovascular responses to isoproterenol. ( Beasley, R; Bremner, P; Buckly, D; Burgess, C; Crane, J; Galletly, D; McHaffie, D; Purdie, G; Robinson, B, 1994)
" We established an isoproterenol (Iso)-induced myocardial injury mouse model and a hypoxia/reoxygenation (H/R)-induced H9c2 cell injury model, followed by pretreatment with apigenin to explore its protective effects."4.31Apigenin alleviates oxidative stress-induced myocardial injury by regulating SIRT1 signaling pathway. ( Dou, L; He, Q; Hei, M; Huang, X; Lan, M; Li, J; Li, W; Liu, B; Shen, T; Sun, S; Tang, W; Wang, H; Wang, J; Xu, K; Yan, M; Yang, Y; Zhang, X; Zhu, K, 2023)
" Here, we investigated the systemic and coronary arterial responses of five anesthetized juvenile American alligators (Alligator mississippiensis) to hypoxia, acetylcholine, adenosine, sodium nitroprusside, isoproterenol, and phenylephrine."3.83Coronary blood flow in the anesthetized American alligator (Alligator mississippiensis). ( Crossley, DA; Elfwing, M; Elsey, RM; Jensen, B; Wang, T, 2016)
" were screened with mice model of acute myocardial hypoxia induced by isoproterenol and pituitrin, eight compounds, i."3.77Anti-hypoxia activity and related components of Rhodobryum giganteum par. ( Cai, Y; Chen, R; Lu, X; Lu, Y; Wei, Q, 2011)
"In this study, the protective effect of pentoxifylline against hypoxia-reoxygenation injury and the possible involvement of nitric oxide (NO)-mediated pathways in this protection were investigated in isolated rat papillary muscles."3.73Pentoxifylline improves reoxygenation-induced contractile recovery through a nitric oxide-dependent mechanism in rat papillary muscles. ( Ahmadi, SH; Dehpour, AR; Ebrahimi, F; Ghasemi, M; Hajrasouliha, AR; Rofoui, BR; Sadeghipour, H; Tavakoli, S, 2006)
" cN-IA overexpression increased adenosine formation and release into the medium caused by simulated hypoxia and by isoproterenol in the absence and presence of inhibitors of adenosine metabolism."3.72Metabolic and functional consequences of cytosolic 5'-nucleotidase-IA overexpression in neonatal rat cardiomyocytes. ( Curto, MA; Freeman, NV; Newby, AC; Sala-Newby, GB, 2003)
"The aim of this study was to examine the effects of acute hypoxia on the slow (I(Ks)) and rapid (I(Kr)) components of the native delayed rectifier K+ channel in the absence and presence of the beta-adrenergic receptor agonist isoproterenol (isoprenaline; Iso) using the whole-cell configuration of the patch-clamp technique."3.72Differential regulation of the slow and rapid components of guinea-pig cardiac delayed rectifier K+ channels by hypoxia. ( Hool, LC, 2004)
"The depression of excitatory synaptic transmission by hypoxia in area CA1 of the hippocampus is largely dependent upon the activation of adenosine A(1) receptors on presynaptic glutamatergic terminals."3.72Adrenoceptor subtype-specific acceleration of the hypoxic depression of excitatory synaptic transmission in area CA1 of the rat hippocampus. ( Frenguelli, BG; Pearson, T, 2004)
"The aim was to study the effects of acidosis and hypoxia on the response of cardiac muscle to inotropic agents which (a) act predominantly by increasing intracellular [Ca2+] (raising extracellular [Ca2+], noradrenaline, isoprenaline) and (b) act partly (phenylephrine) or predominantly (EMD 57033) by increasing myofilament calcium sensitivity."3.69Effects of acidosis and hypoxia on the response of isolated ferret cardiac muscle to inotropic agents. ( Lee, JA; Orchard, CH; Shah, N; Than, N; White, J, 1994)
"The dynamics of the changes in myocardial phosphorylated compound contents (inorganic phosphate: Pi; phosphocreatine: PCr; ATP) induced by 10(-6)M isoprenaline administration was studied, using 31P-NMR spectroscopy, in hearts isolated from rats adapted for three weeks to normobaric hypoxia (10% of oxygen)."3.69Adaptation to chronic hypoxia alters cardiac metabolic response to beta stimulation: novel face of phosphocreatine overshoot phenomenon. ( Aussedat, J; Novel-Chaté, V; Rossi, A; Saks, VA, 1995)
"Temporal and quantitative relations between cytosolic energy metabolism, adenosine efflux, and coronary flow were examined during 10 min of isoproterenol (ISO) infusion (60 nM) or hypoxia (5% O2) in isolated isovolumic rat heart."3.68Adenosine formation and energy metabolism: a 31P-NMR study in isolated rat heart. ( Headrick, JP; Willis, RJ, 1990)
"The role of adenosine in hypoxia-induced vasodilation was examined in the intestine of pentobarbital sodium-anesthetized cats."3.68Hypoxia-induced vasodilation of the feline superior mesenteric artery is not adenosine mediated. ( Lautt, WW; Lockhart, LK, 1990)
" The effect was estimated of preliminary adaptation to intermittent hypobaric hypoxia or to short-term stress exposure on the incidence and the pronouncement of delayed after depolarization and of trigger activity induced by a high frequency stimulation against the background of isoproterenol (10(-8) M)."3.68[The effect of adaptation to stress exposures and to periodic hypoxia on the cardiomyocyte trigger activity of the papillary muscles in the rat]. ( Meerson, FZ; Vovk, VI, 1991)
" 31P-NMR was used to estimate free cytosolic Mg2+ levels ([Mg2+]free) during hypoxia, isoproterenol stimulation, and graded low-flow ischemia in crystalloid perfused, isovolumic rat hearts."3.68Cytosolic free magnesium in stimulated, hypoxic, and underperfused rat heart. ( Headrick, JP; Willis, RJ, 1991)
"A decrease in heart rate response to isoproterenol (IP) infusion has been previously described in humans exposed to acute (2-3 days) or chronic (21 days) exposure to altitude hypoxia (J."3.67Reversal of hypoxia-induced decrease in human cardiac response to isoproterenol infusion. ( Bouissou, P; Keromes, A; Le-Trong, JL; Merlet, P; Rathat, C; Richalet, JP; Veyrac, P, 1989)
"The hypothesis of a blunted chronotropic response of cardiac beta-adrenergic receptors in altitude hypoxia was tested in nine subjects at sea level (SL) by infusion of isoproterenol."3.67Decreased cardiac response to isoproterenol infusion in acute and chronic hypoxia. ( Baud, P; Kéromès, A; Larmignat, P; Lhoste, F; Rathat, C; Richalet, JP, 1988)
" Therefore, we sought to clarify the role of beta-adrenergic receptor activity in carotid body function by assessing: the ventilatory response to intravenous isoproterenol infusion in awake and anesthetized carotid body intact and carotid body denervated goats, the effect of propranolol on the ventilatory response to isocapnic hypoxemia, and carotid sinus nerve chemoreceptor discharge rate response to isoproterenol and hypoxia."3.67Role of beta adrenergic receptors in carotid body function of the goat. ( Bisgard, GE; Hudgel, DW; Kressin, NA; Nielsen, AM, 1986)
"In order to distinguish the effects of beta-receptor stimulation on the ECG from other factors during short-term adjustment to hypoxic aerohypoxia, the ECG of 19 volunteers were compared during moderately acute, stepwise exposure to high altitude (6,000 m) in a low pressure chamber, once with and once without beta-receptor blockade (propranolol), and after isoprenaline inhalation at ground level."3.67The ECG changes due to altitude and to catecholamines. ( Koller, EA; Saurenmann, P, 1984)
"To test the hypothesis that the rate of left ventricular relaxation can be dissociated from left ventricular stiffness, indexes of stiffness and relaxation were evaluated during mild hypoxia and hypoxia with isoproterenol or caffeine in isovolumically beating, isolated rat heart preparations."3.67Separation of rate of left ventricular relaxation from chamber stiffness in rats. ( Iizuka, M; Momomura, S; Serizawa, T; Sugimoto, T, 1988)
" Aortic chemoreceptor responses to steady-state hypoxia (PaO2 range, 100-30 Torr) were measured (a) before and during intravenous infusion of the beta-receptor agonist, isoproterenol (0."3.67Adrenergic mechanisms in oxygen chemoreception in the cat aortic body. ( Lahiri, S; Matsumoto, S; McGregor, KH; Mokashi, A; Mulligan, E, 1986)
"The erythropoietic response, measured as RBC-59Fe uptake, in response to either 24-h exposure to hypoxia or administration of dexamethasone, isoproterenol, testosterone, or erythropoietin, was determined in both posthypoxic (PH) and hypertransfused (HT) polycythemic mice."3.67Comparison of erythropoietic response to erythropoietin-secreting stimuli in mice following polycythemia induced by transfusion or hypoxia. ( Alippi, RM; Barceló, AC; Bozzini, CE, 1985)
" Aconitine, BaCl2 (less than 2 mmol/l) and hypoxia decrease threshold of ac-arrhythmia and ac-asystole, in both tissues to a similar extent, whereas carbachol and BaCl2 (greater than 2 mmol/l) increase threshold."3.67Influence of arrhythmogenic and antiarrhythmic agents on alternating current-induced arrhythmias in guinea-pig heart preparations. ( Borchard, U; Clemm, S; Hirth, C, 1984)
"The electrical and mechanical activities of myocardial strips from Rana pipiens treated with isoproterenol (ISO) were studied during cyanide hypoxia at different bath temperatures (12, 25 and 35 degrees C)."3.67Influence of temperature and cyanide on electrical and mechanical activities of isoproterenol-damaged frog heart. ( Pettersson, AS; Volkmann, R, 1985)
"The aim of this study was to examine the electrophysiological effects of isoprenaline, phenylephrine, and noradrenaline on sheep Purkinje fibers in vitro, superfused either with a normal or with a modified physiological salt solution (PSS) designed to mimic some of the conditions occurring during mild myocardial ischemia (hyperkalemia, hypoxia, and acidosis)."3.67Cardiac electrophysiological effects of isoprenaline, phenylephrine, and noradrenaline on normal and mildly "ischaemic" sheep Purkinje fibers. ( Boachie-Ansah, G; Kane, KA; Parratt, JR, 1989)
"To determine whether the pulmonary vasodilation produced by isoproterenol is mediated solely by its beta adrenergic effects, we studied the hemodynamic responses to isoproterenol in three groups of dogs with pulmonary vasoconstriction produced by continuous ventilation with 10% oxygen: (a) hypoxia alone, (b) hypoxia and propranolol 0."3.66Nonadrenergic effects of isoproterenol in dogs with hypoxic pulmonary vasoconstriction. Possible role of prostaglandins. ( Lazar, JD; Rubin, LJ, 1983)
"Two different conditions responsible for cardiac hypertrophy in the rat were investigated: the first one is isoproterenol-induced myocardial infarct, the second is exposure to hypoxia (0."3.66Myocardial hypertrophy in the rat. Correlation between two experimental models. ( Cacciapuoti, AA; Chiariello, M; Condorelli, M; Ferro, G; Genovese, A, 1980)
"Myocardial necrosis was induced in male Wistar rats by isoproterenol as described by Rona et al."3.66Hypoxic tolerance of rats with isoproterenol-induced myocardial necrosis. ( Bhatia, B; Datta, K; Nijhawan, R, 1980)
"6 km/h), we studied the effect of ozone on ventilatory responses to hypercapnia and to hypoxia."3.66Mechanism of ozone-induced tachypneic response to hypoxia and hypercapnia in conscious dogs. ( Djokic, TD; Dumont, C; Graf, PD; Lee, LY; Nadel, JA, 1980)
"Some circulatory effects of thoracic epidural analgesia (TEA) were investigated in splenectomized, open-chest sheep during normoxia, hypoxia and isoproterenol administration."3.66Cardiovascular effects of epidural analgesia. I. Thoracic epidural analgesia. An experimental study in sheep of the effects on central circulation, regional perfusion and myocardial performance during normoxia, hypoxia and isoproterenol administration. ( Jynge, P; Ottesen, S; Renck, H, 1978)
"A hemodynamic study with blood gas analysis was performed so we could observe changes induced by blood volume expansion, dopamine infusion and isoproterenol infusion in 20 adult patients suffering from peritonitis complicated with septic shock and acute respiratory failure."3.66Venous admixture in human septic shock: comparative effects of blood volume expansion, dopamine infusion and isoproterenol infusion on mismatching of ventilation and pulmonary blood flow in peritonitis. ( Delille, F; Eveleigh, MC; Gurdjian, F; Jardin, F; Margairaz, A, 1979)
"Resistance to isoproterenol-induced cardiac necrosis (IPRO) was compared in rats exposed to two types of hypoxia (i."3.65Experimental cardiac necrosis in hypobaric and anemic hypoxia. ( McGrath, JJ; Ostádal, B; Procházka, J; Rychterova, V; Wachtlova, M, 1975)
" This is true for systemic hypoxia, hemorrhagic shock, and isoproterenol infusion."3.65Transmural metabolic gradients of the canine left ventricle in coronary constriction, systemic hypoxia, hemorrhagic shock, and isoproterenol infusion. ( Leunissen, RL, 1975)
"The effects of isoproterenol, glucose, and pH on the responses of isolated rat cardiac muscle to hypoxia (95% N2, 5% CO2) were examined while the muscles were contracting isometrically 12 times a minute at 28 degrees C."3.65Factors influencing tolerance of cardiac muscle to hypoxia. ( Apstein, CS; Bing, OH; Brooks, WW, 1975)
" Cardiomegaly has been produced in rats by sideropenic anaemia, by isoprenaline or thyroxine or by the application of both drugs, by artificial increase in resistance to blood flow and by long-term adaptation to hypoxia and physical stress."3.65The growth of the muscular and collagenous parts of the rat heart in various forms of cardiomegaly. ( Bartosová, D; Chvapil, M; Korecký, B; Poupa, O; Rakusan, K; Turek, Z; Vízek, M, 1969)
" In addition, in Group A, the effects of hypoxia on the pulmonary circulation were compared and contrasted with those of l-norepinephrine (alpha-receptor stimulator) and isoproterenol (beta-receptor stimulator)."3.64Effects of alpha adrenergic blockade and tissue catecholamine depletion on pulmonary vascular response to hypoxia. ( Grover, RF; Silove, ED, 1968)
"Retinal neovascularization was assessed by CD31 immunohistochemistry."1.38Beta-adrenoreceptor agonism influences retinal responses to hypoxia in a model of retinopathy of prematurity. ( Bagnoli, P; Dal Monte, M; Filippi, L; Latina, V; Martini, D; Pavan, B, 2012)
"Hydrogen sulfide (H2S) is a gaseous signaling molecule that appears to be involved in numerous biological processes, including regulation of blood pressure and vascular tone."1.37Hydrogen sulfide and cerebral microvascular tone in newborn pigs. ( Basuroy, S; Fedinec, AL; Jaggar, JH; Leffler, CW; Parfenova, H; Umstot, ES, 2011)
"In the anoxia-tolerant crucian carp (Carassius carassius) cardiac activity varies according to the seasons."1.36Sinoatrial tissue of crucian carp heart has only negative contractile responses to autonomic agonists. ( Hälinen, M; Haverinen, J; Vornanen, M, 2010)
" Moreover, ACh and Ca(2+) dose-response studies showed that accumulation of cAMP shifted the dose-response curves to the low concentration side, suggesting that it increases Ca(2+) sensitivity in the fusion of the exocytotic cycle."1.31cAMP modulation of Ca(2+)-regulated exocytosis in ACh-stimulated antral mucous cells of guinea pig. ( Fujiwara, S; Imai, Y; Katsu, K; Kojima, K; Nakahari, T; Shimamoto, C, 2002)
"Forty-five normotensive and hypertensive sleep apnea patients (respiratory disturbance index >20) and non-apneic controls."1.30The effects of hypoxia and sleep apnea on isoproterenol sensitivity. ( Ancoli-Israel, S; Clausen, J; Dimsdale, JE; Loredo, JS; Mills, PJ, 1998)
"Propranolol (0."1.30Influence of beta-adrenoceptor agonists on the pulmonary circulation. Effects of a beta3-adrenoceptor antagonist, SR 59230A. ( Advenier, C; Bardou, M; Dumas, JP; Dumas, M; Giudicelli, JF; Rochette, L, 1998)
"1 ml), and dose-response curves to levcromakalim (a KATP channel opener) or isoproterenol were constructed."1.29Role of potassium channels in hypoxic relaxation of porcine bronchi in vitro. ( Croxton, TL; Fernandes, LB; Hirshman, CA; Lindeman, KS, 1994)
" Isolated atrial strips showed a right shift of their dose-response curve to isoprenaline in the presence of the highly selective beta 2-AR antagonist ICI 118,551 at concentrations above 1 x 10(-8) mol/L."1.29The effects of sympathomimetics on the cardiovascular system of sheep. ( Allen, R; Alley, MR; Baxter, S; Burgess, C; Crane, J; Dallimore, JA; Davie, PS; Kealey, AS; Lapwood, KR; Pack, RJ, 1994)
"We exposed fetuses to high-altitude (3,820 m) hypoxemia from 30 to 130 days gestation, when we measured fetal heart rate, right and left ventricular outputs with electromagnetic flow probes, and arterial blood pressure during an isoproterenol dose-response infusion."1.29Effects of isoproterenol on the cardiovascular system of fetal sheep exposed to long-term high-altitude hypoxemia. ( Gilbert, RD; Kamitomo, M; Ohtsuka, T, 1995)
" Dose-response curves were obtained through the sequential injection, via the femoral vein, of increasing doses of methacholine, methoxamine, isoprenaline and substance P."1.29Effects of chronic hypoxia on the secretory responses of rat salivary glands. ( Chiarenza, AP; Elverdin, JC; Frid, AB; Giglio, MJ, 1995)
"1982) and that DADs may explain certain arrhythmias such as those evoked by digitalis toxicity (Ferrier, 1977) or reperfusion (Ferrier et al."1.27Inhibition by simulated ischemia or hypoxia of delayed afterdepolarizations provoked by cyclic AMP: significance for ischemic and reperfusion arrhythmias. ( Coetzee, WA; Opie, LH; Saman, S, 1988)
" The relatively limited cardiac output response and downward trend at the highest dosage of dopamine occurred with a reduction in heart rate and an increase in systemic vascular resistance."1.27Augmentation of cardiac output with intravenous catecholamines in unanesthetized hypoxemic newborn lambs. ( Dreyer, WJ; Fisher, DJ; O'Laughlin, MP; Smith, EO, 1987)
"The effects of 30 min periods of either anoxia or ischemia (stop-flow) on the uptake2 of isoprenaline and on the production of O-methyl-isoprenaline, a major metabolite of isoprenaline formed by catechol-O-methyltransferase (COMT), were examined in the perfused rat heart."1.27Effects of anoxia and ischemia on uptake2 of catecholamines in perfused rat heart. ( Fujiwara, M; Hifumi, K; Inoue, M; Kurahashi, K, 1987)
"Furthermore, the resistance to anoxia of their isolated right ventricle was higher than that of virgin females."1.26The effect of pregnancy and lactation on the development of experimental heart lesions. ( Faltová, E; Mráz, M; Procházka, J; Sedivý, J, 1980)
"In puppies with oxygen deficiency, insulin levels declined, whereas during epinephrine infusion, they remained stable or increased slightly."1.26Beta adrenergic receptor dysfunction in hypoxic inhibition of insulin release. ( Baum, D; Porte, D, 1976)
"When isoproterenol was present in the bathing solution, the decreases in CF and APD produced by hypoxia were accelerated, but ATP and propranolol did not significantly modify the hypoxically induced changes."1.26Effects of hypoxia and metabolic inhibitors on the electrical and mechanical activities of isolated guinea pig papillary muscles. ( Asano, T; Kasuya, Y; Shigenobu, K, 1981)
"Reoxygenation after 10 min of anoxia produced equivalent recovery in both groups working against a 52-mmHg aortic afterload, whereas recovery after 20 or 30 min of anoxia, was depressed in diabetic hearts."1.26Performance of diabetic rat hearts: effects of anoxia and increased work. ( Hawelu-Johnson, C; Ingebretsen, CG; Ingebretsen, WR; Moreau, P, 1980)
"Although anoxia releases noradrenaline from the heart the effect of anoxia on the VFT was not prevented by beta-adrenoceptor blockade with propranolol or pindolol or by previous treatment with reserpine."1.25The effect of anoxia on the ventricular fibrillation threshold in the rabbit isolated heart. ( Murnaghan, MF, 1975)
"Pretreatment with propranolol, 0."1.25Cardiovascular responsiveness to beta-adrenergic stimulation and blockade in chronic hypoxia. ( Cymerman, A; Hartley, LH; Maher, JT; Manchanda, SC; Wolfe, DL, 1975)
" The NE dose-response curves shifted to the left."1.25Potentiation of the contractile effects of norepinephrine by hypoxia. ( Cooper, T; Epstein, SE; Kent, KM, 1972)

Research

Studies (303)

TimeframeStudies, this research(%)All Research%
pre-1990222 (73.27)18.7374
1990's45 (14.85)18.2507
2000's20 (6.60)29.6817
2010's12 (3.96)24.3611
2020's4 (1.32)2.80

Authors

AuthorsStudies
Harter, TS1
Clifford, AM1
Tresguerres, M1
Seaayfan, E1
Nasrah, S1
Quell, L1
Radi, A1
Kleim, M1
Schermuly, RT1
Weber, S1
Laghmani, K1
Kömhoff, M1
Xu, K1
Yang, Y1
Lan, M1
Wang, J1
Liu, B1
Yan, M1
Wang, H1
Li, W1
Sun, S1
Zhu, K1
Zhang, X1
Hei, M1
Huang, X1
Dou, L1
Tang, W1
He, Q1
Li, J1
Shen, T1
Fernández-Morales, JC1
Morad, M1
Mahat, B1
Mauger, JF1
Imbeault, P1
Stephens, OR1
Weiss, K1
Frimel, M1
Rose, JA1
Sun, Y1
Asosingh, K1
Farha, S1
Highland, KB1
Prasad, SVN1
Erzurum, SC1
Mahmud, H1
Candido, WM1
van Genne, L1
Vreeswijk-Baudoin, I1
Yu, H1
van de Sluis, B1
van Deursen, J1
van Gilst, WH1
Silljé, HH1
de Boer, RA1
Jensen, B1
Elfwing, M1
Elsey, RM1
Wang, T1
Crossley, DA1
Béguin, PC1
El-Helou, V1
Assimakopoulos, J1
Clément, R1
Gosselin, H1
Brugada, R1
Villeneuve, L1
Rohlicek, CV2
Del Duca, D1
Lapointe, N1
Rouleau, JL1
Calderone, A1
Guan, Y1
Gao, L1
Ma, HJ1
Li, Q1
Zhang, H1
Yuan, F1
Zhou, ZN1
Zhang, Y1
Vornanen, M1
Hälinen, M1
Haverinen, J1
Cai, Y1
Lu, Y1
Chen, R1
Wei, Q1
Lu, X1
Leffler, CW1
Parfenova, H1
Basuroy, S1
Jaggar, JH1
Umstot, ES1
Fedinec, AL1
Marino, M1
Bény, JL1
Peyter, AC1
Diaceri, G1
Tolsa, JF1
Lindgren, I1
Crossley, D1
Villamor, E1
Altimiras, J1
Dal Monte, M1
Martini, D1
Latina, V1
Pavan, B1
Filippi, L1
Bagnoli, P1
Naggar, I1
Uchida, S1
Kamran, H1
Lazar, J1
Stewart, M1
Tabarov, MS1
Kudryashov, YA1
Hynie, S1
Sída, P1
Klenerová, V1
Asemu, G1
Ost'ádal, B1
Hrbasová, M1
Novotny, J1
Hejnová, L1
Kolár, F1
Neckár, J1
Svoboda, P1
Sala-Newby, GB1
Freeman, NV1
Curto, MA1
Newby, AC1
Bartlett, IS1
Marshall, JM1
HALMAGYI, DF1
COLEBATCH, HJ1
STARZECKI, B1
HORNER, GJ1
HAWKING, F1
FERRANS, VJ1
HIBBS, RG1
BLACK, WC1
WEILBAECHER, DG1
BLATTEIS, CM1
SEGAL, S1
CUMMING, GR1
KORB, G1
FOLLE, LE2
AVIADO, DM2
Pei, JM2
Kravtsov, GM1
Wu, S1
Das, R1
Fung, ML3
Wong, TM3
Hool, LC1
Eigel, BN1
Gursahani, H1
Hadley, RW1
Pearson, T1
Frenguelli, BG1
Viau, S1
Trieu, P1
Hébert, TE1
Worthley, MI1
Horowitz, JD1
Zeitz, CJ1
Schwenke, DO1
Pearson, JT1
Mori, H1
Shirai, M1
Ebrahimi, F1
Hajrasouliha, AR1
Tavakoli, S1
Sadeghipour, H1
Ghasemi, M1
Rofoui, BR1
Ahmadi, SH1
Dehpour, AR1
Waddell, JA1
Emerson, PA1
Gunstone, RF1
Cowsert, MK1
Carrier, O1
Leszkovszky, GP1
Gál, G1
Tardos, L1
Pisanty, J1
Thilenius, OG1
Candiolo, BM1
Beug, JL1
Dobson, JG3
Schrader, J1
Saurenmann, P1
Koller, EA1
Titus, EO1
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Tuleutaev, TB1
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Juhász-Nagy, A3
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Antezana, G1
Spielvogel, H1
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Muccitelli, RM1
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Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pulmonary Arterial Hypertension Treatment With Carvedilol for Heart Failure[NCT01586156]30 participants (Actual)Interventional2012-12-31Completed
Hemodynamics and Extravascular Lung Water in Acute Lung Injury: A Prospective Randomized Controlled Multicentered Trial of Goal Directed Treatment of EVLW Versus Standard Management for the Treatment of Acute Lung Injury[NCT00624650]Phase 233 participants (Actual)Interventional2008-02-29Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

6 Minute Walk Test

We hypothesized that carvedilol would not worsen 6 minute walk distance. (NCT01586156)
Timeframe: 6 months

,,
Interventionmeters (Mean)
baseline3 months6 months
Escalation-dose Carvedilol438438450
Low-fixed-dose Carvedilol504504486
Placebo Arm404412453

Beta-Adrenergic Receptor (Alprenolol Binding Assay)

We hypothesize that use of carvedilol in patients with PAH will increase beta- adrenergic receptor availability, and this will be measurable as a increase in alprenolol binding over time of drug use. (NCT01586156)
Timeframe: 6 months

,,
Interventionabritrary units (Mean)
baseline6 months
Escalation-dose Carvedilol8277983730
Low-fixed-dose Carvedilol8523084554
Placebo Arm9225479083

Cardiac Glucose Uptake in FDG-PET (Fluorodeoxyglucose-Positron Emission Tomography)

We hypothesize that use of carvedilol in patients with PAH (Pulmonary Arterial Hypertension) will decrease the cardiac glucose utilization, and this will be measurable as a drop in fasting FDG-PET standardized uptake values of the heart at 6 months as compared to baseline (NCT01586156)
Timeframe: 6 months

,,
Interventionstandardized uptake value (SUV) (Median)
baseline FDG-PET6 month FDG-PET
Escalation-dose Carvedilol0.90.7
Low-fixed-dose Carvedilol0.60.6
Placebo Arm1.00.8

Echocardiogram Left Ventricular Cardiac Output

We hypothesized that carvedilol would be safe and tolerable and thus that Left ventricular cardiac output, a measure of heart function, would not decrease in participants on carvedilol. (NCT01586156)
Timeframe: 6 months

,,
InterventionL/min (Mean)
baseline3 months6 months
Escalation-dose Carvedilol4.54.84.9
Low-fixed-dose Carvedilol5.24.64.7
Placebo Arm4.74.74.5

Echocardiogram Right Ventricular Systolic Pressure (RVSP)

We hypothesized that RVSP might decrease in participants on carvedilol. (NCT01586156)
Timeframe: 6 months

,,
Interventionmm Hg (Mean)
baseline3 months6 months
Escalation-dose Carvedilol635464
Low-fixed-dose Carvedilol635951
Placebo Arm767866

NT-proBNP (N-terminal Pro-B Type Natriuretic Peptide)

We hypothesized that carvedilol would be safe and tolerable and thus that NT-BNP, a measure of heart failure, would not increase in participants on carvedilol. (NCT01586156)
Timeframe: 6 months

,,
Interventionpg/ml (Median)
baseline1 month3 months6 months
Escalation-dose Carvedilol127120169146
Low-fixed-dose Carvedilol57927952
Placebo Arm170183152293

Urinary cAMP (Cyclic Adenosine Monophosphate)/Creatinine

We hypothesize that use of carvedilol in patients with PAH will increase beta adrenergic receptor function and this will be measurable as an increase in cAMP measured in the urine at 6 months in participants in dose escalation carvedilol. (NCT01586156)
Timeframe: 6 months

,,
Interventionumol/g (Median)
baseline1 month3 months6 months
Escalation-dose Carvedilol1.00.71.51.0
Low-fixed-dose Carvedilol0.60.80.60.7
Placebo Arm1.41.31.21.4

Reviews

9 reviews available for isoproterenol and Hypoxia

ArticleYear
A molecular biologic approach to cardiac toxicology.
    Advances in experimental medicine and biology, 1983, Volume: 161

    Topics: Acrylamides; Animals; Calcium; Cnidarian Venoms; Coronary Disease; Doxorubicin; Egtazic Acid; Electr

1983
Long-term treatment with beta2-adrenostimulants in asthma. Side effects, selectivity, tolerance, and routes of administration.
    Acta medica Scandinavica. Supplementum, 1977, Volume: 608

    Topics: Administration, Oral; Adrenergic beta-Agonists; Aerosols; Albuterol; Arrhythmias, Cardiac; Asthma; E

1977
Adrenergic stimulants and asthma mortality.
    Scandinavian journal of respiratory diseases. Supplementum, 1977, Volume: 101

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Asthma; Bronchi; Chloro

1977
Alterations of myocardial adenine nucleotide metabolism.
    Recent advances in studies on cardiac structure and metabolism, 1975, Volume: 7

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals

1975
The pathophysiologic vulnerability of the subendocardium of the left ventricle.
    Advances in cardiology, 1973, Volume: 9

    Topics: Arrhythmias, Cardiac; Capillaries; Cardiomegaly; Coronary Disease; Coronary Vessels; Endocardium; He

1973
Advances in asthma. Treatment.
    British medical journal, 1969, Nov-08, Volume: 4, Issue:5679

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Asthma; Bronchodilator Agents; Carbon Dioxide;

1969
A review of current concepts and research in shock.
    The Ohio State medical journal, 1968, Volume: 64, Issue:6

    Topics: Blood Transfusion; Extracellular Space; Homeostasis; Humans; Hypoxia; Isoproterenol; Mephentermine;

1968
Management of arrhythmias in acute myocardial infarction.
    American family physician, 1971, Volume: 4, Issue:1

    Topics: Acid-Base Equilibrium; Adams-Stokes Syndrome; Arrhythmias, Cardiac; Atropine; Bradycardia; Cardiac O

1971
Effects of hypoxia and ischemia on myocardial contraction. Alterations in the time course of force and ischemia-dependent inhomogeneity of contractility.
    Cardiology, 1971, Volume: 56, Issue:1

    Topics: Animals; Coronary Disease; Heart; Heart Ventricles; Humans; Hypoxia; In Vitro Techniques; Isoprotere

1971

Trials

8 trials available for isoproterenol and Hypoxia

ArticleYear
The effect of hypercapnia and hypoxemia on the cardiovascular responses to isoproterenol.
    Clinical pharmacology and therapeutics, 1994, Volume: 56, Issue:3

    Topics: Adult; Analysis of Variance; Carbon Dioxide; Cardiovascular System; Humans; Hypercapnia; Hypoxia; Is

1994
O2 extraction maintains O2 uptake during submaximal exercise with beta-adrenergic blockade at 4,300 m.
    Journal of applied physiology (Bethesda, Md. : 1985), 1998, Volume: 85, Issue:3

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Altitude; Blood Gas Analysis; Diet; Ex

1998
Decrease of subcutaneous adipose tissue lipolysis after exposure to hypoxia during a simulated ascent of Mt Everest.
    Pflugers Archiv : European journal of physiology, 1999, Volume: 439, Issue:1-2

    Topics: Adipose Tissue; Adrenergic Agonists; Adrenergic beta-Agonists; Adult; Altitude; Body Composition; Ep

1999
Effects of adrenergic stimulation on ventilation in man.
    The Journal of clinical investigation, 1972, Volume: 51, Issue:6

    Topics: Adult; Analysis of Variance; Angiotensin II; Carbon Dioxide; Chemoreceptor Cells; Clinical Trials as

1972
Effect of drugs, hypoxia, and ventilatory maneuvers on lung diffusion for CO in man.
    Journal of applied physiology, 1972, Volume: 32, Issue:6

    Topics: Adult; Carbon Monoxide; Clinical Trials as Topic; Epinephrine; Humans; Hyperventilation; Hypoxia; Is

1972
Lung function in provoked asthma: responses to inhaled urea, methacholine and isoprenaline.
    Clinical science, 1972, Volume: 43, Issue:6

    Topics: Adolescent; Adult; Aged; Airway Resistance; Asthma; Carbon Dioxide; Female; Humans; Hypoxia; Isoprot

1972
Effects of isoprenaline plus phenylephrine by pressurized aerosol on blood gases, ventilation, and perfusion in chronic obstructive lung disease.
    British medical journal, 1970, Dec-05, Volume: 4, Issue:5735

    Topics: Adult; Aerosols; Aged; Carbon Dioxide; Cardiac Output; Chronic Disease; Clinical Trials as Topic; Fe

1970
Comparison of the effect on blood gases, ventilation, and perfusion of isoproterenol-phenylephrine and salbutamol aerosols in chronic bronchitis with asthma.
    The Journal of allergy and clinical immunology, 1972, Volume: 49, Issue:2

    Topics: Adult; Aerosols; Aged; Asthma; Blood Gas Analysis; Bronchitis; Bronchodilator Agents; Carbon Dioxide

1972

Other Studies

286 other studies available for isoproterenol and Hypoxia

ArticleYear
Adrenergically induced translocation of red blood cell β-adrenergic sodium-proton exchangers has ecological relevance for hypoxic and hypercapnic white seabass.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2021, 11-01, Volume: 321, Issue:5

    Topics: Acclimatization; Adrenergic beta-Agonists; Animals; Bass; Ecosystem; Erythrocytes; Fish Proteins; Hy

2021
Reciprocal Regulation of MAGED2 and HIF-1α Augments Their Expression under Hypoxia: Role of cAMP and PKA Type II.
    Cells, 2022, 10-29, Volume: 11, Issue:21

    Topics: Adaptor Proteins, Signal Transducing; Antigens, Neoplasm; Colforsin; Cyclic AMP-Dependent Protein Ki

2022
Apigenin alleviates oxidative stress-induced myocardial injury by regulating SIRT1 signaling pathway.
    European journal of pharmacology, 2023, Apr-05, Volume: 944

    Topics: Animals; Apigenin; Apoptosis; Hypoxia; Isoproterenol; Mice; Molecular Docking Simulation; Myocytes,

2023
Regulation of Ca
    Journal of molecular and cellular cardiology, 2018, Volume: 114

    Topics: Acidosis; Acute Disease; Animals; Animals, Newborn; Barium; Biological Transport; Calcium; Calcium C

2018
Effects of different oxygen tensions on differentiated human preadipocytes lipid storage and mobilisation.
    Archives of physiology and biochemistry, 2021, Volume: 127, Issue:1

    Topics: Adipocytes; Adipose Tissue; Adult; Cell Differentiation; Female; Humans; Hypoxia; Isoproterenol; Lip

2021
Interdependence of hypoxia and β-adrenergic receptor signaling in pulmonary arterial hypertension.
    American journal of physiology. Lung cellular and molecular physiology, 2019, 09-01, Volume: 317, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Familial Primary Pulmonary Hypertension; Heart Ventricles; Hum

2019
Cardiac function and architecture are maintained in a model of cardiorestricted overexpression of the prorenin-renin receptor.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Animals; Blood Pressure; Blotting, Western; Cardiomegaly; Creatine Kinase; Echocardiography; Gene Ex

2014
Coronary blood flow in the anesthetized American alligator (Alligator mississippiensis).
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2016, Volume: 191

    Topics: Acetylcholine; Adenosine; Alligators and Crocodiles; Anesthesia; Animals; Coronary Circulation; Coro

2016
The phenotype and potential origin of nestin+ cardiac myocyte-like cells following infarction.
    Journal of applied physiology (Bethesda, Md. : 1985), 2009, Volume: 107, Issue:4

    Topics: Adrenergic beta-Agonists; Animals; Cell Differentiation; Cell Movement; Connexin 43; Disease Models,

2009
Chronic intermittent hypobaric hypoxia decreases beta-adrenoceptor activity in right ventricular papillary muscle.
    American journal of physiology. Heart and circulatory physiology, 2010, Volume: 298, Issue:4

    Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Body Weight; Dose-Response Relationship, Drug;

2010
Sinoatrial tissue of crucian carp heart has only negative contractile responses to autonomic agonists.
    BMC physiology, 2010, Jun-11, Volume: 10

    Topics: Acclimatization; Action Potentials; Animals; Calcium Channels; Calcium Channels, L-Type; Carbachol;

2010
Anti-hypoxia activity and related components of Rhodobryum giganteum par.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2011, Jan-15, Volume: 18, Issue:2-3

    Topics: Animals; Bryophyta; Cinnamates; Coumarins; Disease Models, Animal; Hypoxia; Isoproterenol; Male; Mic

2011
Hydrogen sulfide and cerebral microvascular tone in newborn pigs.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 300, Issue:2

    Topics: Animals; Animals, Newborn; Arterioles; Brain Chemistry; Capillaries; Cerebrovascular Circulation; Cy

2011
Perinatal hypoxia enhances cyclic adenosine monophosphate-mediated BKCa channel activation in adult murine pulmonary artery.
    Journal of cardiovascular pharmacology, 2011, Volume: 57, Issue:2

    Topics: Age Factors; Animals; Colforsin; Cyclic AMP; Female; Hypoxia; Isoproterenol; Large-Conductance Calci

2011
Hypotension in the chronically hypoxic chicken embryo is related to the β-adrenergic response of chorioallantoic and femoral arteries and not to bradycardia.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2011, Volume: 301, Issue:4

    Topics: Adrenergic beta-Agonists; Animals; Arteries; Blood Pressure; Bradycardia; Catecholamines; Chick Embr

2011
Beta-adrenoreceptor agonism influences retinal responses to hypoxia in a model of retinopathy of prematurity.
    Investigative ophthalmology & visual science, 2012, Apr-24, Volume: 53, Issue:4

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Arrestins; beta-Arrestins; Blood Pressure; Blo

2012
Autonomic boundary conditions for ventricular fibrillation and their implications for a novel defibrillation technique.
    The journal of physiological sciences : JPS, 2012, Volume: 62, Issue:6

    Topics: Animals; Arrhythmias, Cardiac; Atropine; Cholinergic Neurons; Heart Rate; Heart Ventricles; Hypoxia;

2012
Dilatory humoral adrenergic reactions of regional veins and arteries during systemic hypoxia and hypothermia.
    Bulletin of experimental biology and medicine, 2002, Volume: 133, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Arteries; Cats; Hypothermia; Hypoxia; Intestine, Small; Isoproter

2002
Exposure to intermittent high altitude induces different changes in adenylyl cyclase activity in hearts of young and adult Wistar rats.
    Journal of receptor and signal transduction research, 2003, Volume: 23, Issue:1

    Topics: Adaptation, Physiological; Adenylyl Cyclases; Altitude; Altitude Sickness; Animals; Colforsin; Enzym

2003
Altered myocardial Gs protein and adenylyl cyclase signaling in rats exposed to chronic hypoxia and normoxic recovery.
    Journal of applied physiology (Bethesda, Md. : 1985), 2003, Volume: 94, Issue:6

    Topics: Adenylyl Cyclases; Animals; Atmospheric Pressure; Body Weight; Cardiotonic Agents; Chronic Disease;

2003
Metabolic and functional consequences of cytosolic 5'-nucleotidase-IA overexpression in neonatal rat cardiomyocytes.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 285, Issue:3

    Topics: 5'-Nucleotidase; Adenosine Triphosphate; Adenoviridae; Animals; Animals, Newborn; Cardiotonic Agents

2003
Effects of chronic systemic hypoxia on contraction evoked by noradrenaline in the rat iliac artery.
    Experimental physiology, 2003, Volume: 88, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Animals; Carbon Dioxide; Chronic Disease; Do

2003
PULMONARY ALVEOLAR-VASCULAR REFLEX.
    Journal of applied physiology, 1964, Volume: 19

    Topics: Acetylcholine; Animals; Atropine; Homeostasis; Hypoxia; Isoproterenol; Lung; Physiology; Pulmonary C

1964
THE PERIODICITY OF MICROFILARIAE. VIII. FURTHER OBSERVATIONS ON WUCHERERIA BANCROFTI.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1964, Volume: 58

    Topics: Acetylcholine; Adrenal Glands; Animals; Blood; Filariasis; Guyana; Heart Failure; Histamine; Humans;

1964
ISOPROTERENOL-INDUCED MYOCARDIAL NECROSIS. A HISTOCHEMICAL AND ELECTRON MICROSCOPIC STUDY.
    American heart journal, 1964, Volume: 68

    Topics: Coronary Disease; Electron Transport Complex IV; Electrons; Fluorescence; Glycogen; Heart Diseases;

1964
HYPOXIA AND THE METABOLIC RESPONSE TO COLD IN NEW-BORN RABBITS.
    The Journal of physiology, 1964, Volume: 172

    Topics: Animals; Animals, Newborn; Carotid Sinus; Cold Temperature; Epinephrine; Hypoxia; Isoproterenol; Met

1964
INHALATION THERAPY.
    Canadian Medical Association journal, 1965, Jan-09, Volume: 92

    Topics: Acetylcysteine; Anti-Bacterial Agents; Bronchial Spasm; Cysteine; Drug Therapy; Epinephrine; Equipme

1965
EFFECT OF ISOPROTERENOL ON RIGHT TO LEFT SHUNTS IN PATIENTS WITH PULMONARY STENOSIS: REPRODUCTION OF ANOXIC ATTACKS.
    The American journal of cardiology, 1965, Volume: 15

    Topics: Angiocardiography; Child; Diagnosis; Dye Dilution Technique; Heart Defects, Congenital; Humans; Hypo

1965
[ELECTRON MICROSCOPIC STUDIES ON MYOCARDIAL LESIONS CAUSED BY ALUDRIN (ISOPROTERENOL SULFATE)].
    Virchows Archiv fur pathologische Anatomie und Physiologie und fur klinische Medizin, 1965, Apr-20, Volume: 339

    Topics: Electrons; Heart Diseases; Hypoxia; Isoproterenol; Microscopy; Microscopy, Electron; Rats; Research;

1965
CARDIOVASCULAR EFFECTS OF ANOXIA AND THE INFLUENCE OF A NEW BETA ADRENERGIC RECEPTOR BLOCKING DRUG.
    The Journal of pharmacology and experimental therapeutics, 1965, Volume: 149

    Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Blood Vessels; Cardiovascular System; Coronary

1965
Calcium homeostasis in rat cardiomyocytes during chronic hypoxia: a time course study.
    American journal of physiology. Cell physiology, 2003, Volume: 285, Issue:6

    Topics: Adrenergic beta-Agonists; Animals; Caffeine; Calcium; Calcium-Transporting ATPases; Cells, Cultured;

2003
Differential regulation of the slow and rapid components of guinea-pig cardiac delayed rectifier K+ channels by hypoxia.
    The Journal of physiology, 2004, Feb-01, Volume: 554, Issue:Pt 3

    Topics: Animals; Cardiotonic Agents; Colforsin; Delayed Rectifier Potassium Channels; Guinea Pigs; Histamine

2004
Na+/Ca2+ exchanger plays a key role in inducing apoptosis after hypoxia in cultured guinea pig ventricular myocytes.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 287, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Apoptosis; Cells, Cultured; Endothelin

2004
Adrenoceptor subtype-specific acceleration of the hypoxic depression of excitatory synaptic transmission in area CA1 of the rat hippocampus.
    The European journal of neuroscience, 2004, Volume: 20, Issue:6

    Topics: Adenosine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Animal

2004
Effects of neonatal hypoxia in the rat on inotropic stimulation of the adult heart.
    Cardiovascular research, 2005, Mar-01, Volume: 65, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Animals, Newborn; Body Weight; Cardiotonic Agents; Dobutamine;

2005
Lack of inotropic effect of nitric oxide on the rat myocardium.
    Clinical and experimental pharmacology & physiology, 2005, Volume: 32, Issue:7

    Topics: Adrenergic beta-Agonists; Animals; Hypoxia; In Vitro Techniques; Isoproterenol; Male; Muscle Contrac

2005
Does central nitric oxide elicit pulmonary hypertension in conscious rats?
    Respiratory physiology & neurobiology, 2006, Oct-27, Volume: 153, Issue:3

    Topics: Adrenergic beta-Agonists; Analysis of Variance; Animals; Blood Pressure; Enzyme Inhibitors; Heart Ra

2006
Pentoxifylline improves reoxygenation-induced contractile recovery through a nitric oxide-dependent mechanism in rat papillary muscles.
    Journal of cardiovascular pharmacology, 2006, Volume: 47, Issue:4

    Topics: Adrenergic beta-Agonists; Animals; Enzyme Inhibitors; Hypoxia; In Vitro Techniques; Isoproterenol; M

2006
Hypoxia in bronchial asthma.
    British medical journal, 1967, May-13, Volume: 2, Issue:5549

    Topics: Adult; Aged; Asthma; Blood Gas Analysis; Child; Female; Humans; Hypoxia; Isoproterenol; Male; Middle

1967
The effect of some autonomic drugs on the uric acidemia of hemorrhagic shock.
    Canadian journal of physiology and pharmacology, 1967, Volume: 45, Issue:1

    Topics: Animals; Blood Pressure; Dogs; Female; Hypoxia; Isoproterenol; Male; Norepinephrine; Phenoxybenzamin

1967
Correlation between functional and morphological heart changes due to isoproterenol.
    Experientia, 1967, Feb-15, Volume: 23, Issue:2

    Topics: Animals; Drug Synergism; Electrocardiography; Heart; Hypoxia; Ischemia; Isoproterenol; Male; Rats; V

1967
The influence of a new adrenergic beta receptor (MJ 1999) blocking drug on the pulmonary circulation.
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 168, Issue:2

    Topics: Animals; Dogs; Electric Stimulation; Hypoxia; Isoproterenol; Pulmonary Circulation; Sympatholytics;

1967
Effect of adrenergic blockade on hypoxia-induced pulmonary vasoconstriction in awake dogs.
    The American journal of physiology, 1967, Volume: 213, Issue:4

    Topics: Animals; Blood Gas Analysis; Blood Pressure; Cardiovascular System; Dogs; Heart Rate; Hydrogen-Ion C

1967
Role of extracellular and intracellular adenosine in the attenuation of catecholamine evoked responses in guinea pig heart.
    Journal of molecular and cellular cardiology, 1984, Volume: 16, Issue:9

    Topics: Adenosine; Animals; Catecholamines; Cyclic AMP; Extracellular Space; Female; Glycogen; Guinea Pigs;

1984
The ECG changes due to altitude and to catecholamines.
    European journal of applied physiology and occupational physiology, 1984, Volume: 53, Issue:1

    Topics: Altitude; Altitude Sickness; Catecholamines; Electrocardiography; Heart Rate; Humans; Hypoxia; Isopr

1984
Influence of cyclic nucleotides on the internal longitudinal resistance and contractures in the normal and hypoxic mammalian cardiac muscle.
    Journal of molecular and cellular cardiology, 1982, Volume: 14, Issue:5

    Topics: Acetylcholine; Animals; Bucladesine; Cats; Cyclic GMP; Electric Conductivity; Electrophysiology; Hea

1982
Biogenic amine-stimulated cyclic adenosine-3',5'-monophosphate formation in the rat carotid body.
    Journal of neurochemistry, 1983, Volume: 41, Issue:3

    Topics: Adenosine; Animals; Biogenic Amines; Carotid Body; Cyclic AMP; Dose-Response Relationship, Drug; His

1983
Nonadrenergic effects of isoproterenol in dogs with hypoxic pulmonary vasoconstriction. Possible role of prostaglandins.
    The Journal of clinical investigation, 1983, Volume: 71, Issue:5

    Topics: Animals; Blood Pressure; Cyclooxygenase Inhibitors; Dogs; Female; Hemodynamics; Hypoxia; Isoproteren

1983
Myocardial hypertrophy in the rat. Correlation between two experimental models.
    Japanese heart journal, 1980, Volume: 21, Issue:4

    Topics: Animals; Cardiomegaly; Disease Models, Animal; Heart; Hypoxia; Isoproterenol; Male; Myocardial Infar

1980
The effect of pregnancy and lactation on the development of experimental heart lesions.
    Physiologia Bohemoslovaca, 1980, Volume: 29, Issue:4

    Topics: Animals; Cardiomyopathies; Female; Hypoxia; In Vitro Techniques; Isoproterenol; Lactation; Myocardia

1980
Influence of arrhythmogenic and antiarrhythmic agents on alternating current-induced arrhythmias in guinea-pig heart preparations.
    Archives internationales de pharmacodynamie et de therapie, 1984, Volume: 269, Issue:1

    Topics: Aconitine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Barium; Barium Compounds; Calcium

1984
Chronic propranolol treatment decreases pulmonary artery pressure in conscious dogs.
    Clinical physiology and biochemistry, 1984, Volume: 2, Issue:4

    Topics: Animals; Blood Pressure; Cardiac Output; Dogs; Heart Rate; Hemodynamics; Hypoxia; Isoproterenol; Mec

1984
Vascular structure in lung tissue obtained at biopsy correlated with pulmonary hemodynamic findings after repair of congenital heart defects.
    Circulation, 1984, Volume: 69, Issue:4

    Topics: Autopsy; Cardiac Output; Cardiac Surgical Procedures; Heart Defects, Congenital; Hemodynamics; Human

1984
Sensitivity and resistance of the myocardium to the toxicity of isoproterenol in rats.
    Advances in experimental medicine and biology, 1983, Volume: 161

    Topics: Adipose Tissue; Animals; Body Weight; Dose-Response Relationship, Drug; Heart; Heart Rate; Hypoxia;

1983
Elevated blood taurine levels after myocardial infarction of cardiovascular surgery: is there any significance?
    Advances in experimental medicine and biology, 1981, Volume: 139

    Topics: Animals; Cardiac Surgical Procedures; Coronary Artery Bypass; Creatine Kinase; Dogs; Heart; Humans;

1981
The healing of frog heart lesions induced by isoproterenol injections.
    Acta pathologica, microbiologica, et immunologica Scandinavica. Section A, Pathology, 1982, Volume: 90, Issue:1

    Topics: Animals; Cyanides; Heart; Heart Aneurysm; Hypoxia; Isoproterenol; Microscopy, Electron; Myocardial C

1982
Stress hyperglycemia and the adrenergic regulation of pancreatic hormones in hypoxia.
    Metabolism: clinical and experimental, 1980, Volume: 29, Issue:11 Suppl 1

    Topics: Animals; Blood Glucose; Dogs; Epinephrine; Glucagon; Hyperglycemia; Hypoxia; Insulin; Isoproterenol;

1980
Performance of diabetic rat hearts: effects of anoxia and increased work.
    The American journal of physiology, 1980, Volume: 239, Issue:5

    Topics: Animals; Blood Glucose; Blood Pressure; Cardiac Output; Coronary Circulation; Diabetes Mellitus, Exp

1980
Gas exchange at rest and during exercise in adults with cystic fibrosis.
    The American review of respiratory disease, 1982, Volume: 125, Issue:4

    Topics: Adolescent; Adult; Arteries; Biomechanical Phenomena; Cystic Fibrosis; Female; Hemodynamics; Humans;

1982
Comparison of the effects of dobutamine, dopamine, and isoproterenol on hypoxic pulmonary vasoconstriction in the pig.
    Critical care medicine, 1982, Volume: 10, Issue:6

    Topics: Animals; Blood Pressure; Catecholamines; Dobutamine; Dopamine; Dose-Response Relationship, Drug; Hyp

1982
Measurements of oxygen tension in perfusates from guinea pig isolated hearts and the demonstration of coronary vasodilator material.
    Journal of pharmacological methods, 1982, Volume: 7, Issue:2

    Topics: Animals; Coronary Vessels; Female; Guinea Pigs; Hypoxia; In Vitro Techniques; Isoproterenol; Male; M

1982
Heterogeneous behavior of the canine arterial and venous wall. Importance of the endothelium.
    Circulation research, 1982, Volume: 51, Issue:4

    Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Animals; Arachidonic Acids; Arteries; Cattle; Dogs

1982
Isoproterenol induces amplification of the erythropoietin-responsive cell compartment.
    Acta physiologica latino americana, 1982, Volume: 32, Issue:3

    Topics: Animals; Cell Compartmentation; Erythrocytes; Erythropoiesis; Erythropoietin; Female; Hypoxia; Iron

1982
Augmentation of carotid body chemoreceptor responses by isoproterenol in the cat.
    Respiration physiology, 1981, Volume: 44, Issue:3

    Topics: Acetazolamide; Animals; Carotid Body; Cats; Chemoreceptor Cells; Female; Hypoxia; Injections, Intra-

1981
Effects of hypoxia and metabolic inhibitors on the electrical and mechanical activities of isolated guinea pig papillary muscles.
    Journal of pharmacobio-dynamics, 1981, Volume: 4, Issue:5

    Topics: 2,4-Dinitrophenol; Action Potentials; Adenosine Triphosphate; Animals; Dinitrophenols; Guinea Pigs;

1981
Effect of isoproterenol on regional pulmonary perfusion and its blockade by propranolol.
    The Tohoku journal of experimental medicine, 1981, Volume: 134, Issue:1

    Topics: Animals; Blood Gas Analysis; Dogs; Hypoxia; Isoproterenol; Perfusion; Propranolol; Pulmonary Circula

1981
Mechanism of ozone-induced tachypneic response to hypoxia and hypercapnia in conscious dogs.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1980, Volume: 48, Issue:1

    Topics: Animals; Atropine; Bronchi; Constriction; Dogs; Hypercapnia; Hypoxia; Isoproterenol; Ozone; Respirat

1980
Cardiopulmonary function in the dog with Dirofilaria immitis infection: during infection and after treatment.
    American journal of veterinary research, 1980, Volume: 41, Issue:3

    Topics: Animals; Blood Pressure; Cardiac Output; Dirofilariasis; Dog Diseases; Dogs; Heart; Heart Rate; Hype

1980
Hypoxic tolerance of rats with isoproterenol-induced myocardial necrosis.
    Advances in myocardiology, 1980, Volume: 2

    Topics: Adrenalectomy; Animals; Atmosphere Exposure Chambers; Heart; Hydrocortisone; Hypoxia; Isoproterenol;

1980
Effects of chronic hypoxia on the secretory responses of rat salivary glands.
    Archives of oral biology, 1995, Volume: 40, Issue:5

    Topics: Animals; Barotrauma; Chronic Disease; Female; Hypoxia; Isoproterenol; Methacholine Chloride; Methoxa

1995
Effects of isoproterenol on the cardiovascular system of fetal sheep exposed to long-term high-altitude hypoxemia.
    Journal of applied physiology (Bethesda, Md. : 1985), 1995, Volume: 78, Issue:5

    Topics: Altitude; Animals; Blood Gas Analysis; Body Weight; Cardiovascular System; Dose-Response Relationshi

1995
Facilitation of beta-adrenoceptor-mediated slow channel responses by hypoxia in guinea pig ventricular myocardium.
    Journal of electrocardiology, 1993, Volume: 26, Issue:1

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Caffeine; Catecholamines; Electrophysiology; Guine

1993
Enhancement of endothelium-dependent contraction of the canine coronary artery by UW solution.
    Transplantation, 1994, Dec-27, Volume: 58, Issue:12

    Topics: Acetylcholine; Adenosine; Allopurinol; Animals; Arginine; Cell Communication; Coronary Vessels; Dino

1994
The effects of sympathomimetics on the cardiovascular system of sheep.
    Clinical and experimental pharmacology & physiology, 1994, Volume: 21, Issue:10

    Topics: Albuterol; Animals; Cardiovascular System; Dobutamine; Female; Fenoterol; Hypoxia; Isoproterenol; Pr

1994
Selective inhibition of cyclic adenosine monophosphate-mediated pulmonary vasodilation by acute hypoxia.
    Surgery, 1995, Volume: 117, Issue:3

    Topics: Acetylcholine; Acute Disease; Animals; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Hypoxia; In Vi

1995
Endothelium-dependent contraction of canine coronary artery is enhanced after 24 hours of preservation with University of Wisconsin solution.
    Transplantation proceedings, 1995, Volume: 27, Issue:1

    Topics: Acetylcholine; Adenosine; Adenosine Diphosphate; Allopurinol; Animals; Coronary Vessels; Dinoprost;

1995
Effects of catecholamines on the residual sodium channel dependent slow conduction in guinea pig ventricular muscles under normoxia and hypoxia.
    Cardiovascular research, 1995, Volume: 29, Issue:1

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Calcium Channels; Catecholamines; Dose-Response Re

1995
Effects of acidosis and hypoxia on the response of isolated ferret cardiac muscle to inotropic agents.
    Cardiovascular research, 1994, Volume: 28, Issue:8

    Topics: Acidosis; Animals; Calcium; Cardiotonic Agents; Dose-Response Relationship, Drug; Ferrets; Hypoxia;

1994
The catecholamine sensitivity of adult rats is enhanced after prenatal hypoxia.
    Biology of the neonate, 1994, Volume: 66, Issue:2-3

    Topics: Animals; Aspartate Aminotransferases; Birth Weight; Creatine Kinase; Female; Heart; Hypoxia; Isoenzy

1994
The myocardial effects of fenoterol, isoprenaline and salbutamol in normoxic and hypoxic sheep.
    International journal of experimental pathology, 1994, Volume: 75, Issue:5

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Female; Fenoterol; Heart; Heart Rate; Hypokalemia; Hyp

1994
Role of potassium channels in hypoxic relaxation of porcine bronchi in vitro.
    The American journal of physiology, 1994, Volume: 266, Issue:3 Pt 1

    Topics: Animals; Benzopyrans; Bronchi; Bronchodilator Agents; Carbachol; Cromakalim; Dose-Response Relations

1994
Downregulation of oxygen demand in isoprenaline stimulated canine myocardium.
    Cardiovascular research, 1993, Volume: 27, Issue:8

    Topics: Animals; Coronary Circulation; Dogs; Down-Regulation; Female; Hypoxia; Isoproterenol; Male; Myocardi

1993
Visualization of high- and low-affinity beta-adrenergic receptors in rat lung: upregulation by chronic hypoxia.
    The American journal of physiology, 1993, Volume: 265, Issue:4 Pt 1

    Topics: Animals; Autoradiography; Chronic Disease; Guanylyl Imidodiphosphate; Hypoxia; Isoproterenol; Lung;

1993
Enhanced receptor-dependent inositol phosphate accumulation in hypoxic myocytes.
    The American journal of physiology, 1993, Volume: 265, Issue:2 Pt 2

    Topics: Animals; Carbachol; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Heart Ventricles;

1993
Pseudomonas aeruginosa exotoxin A enhances automaticity and potentiates hypoxic depression of isolated rat hearts.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1993, Volume: 202, Issue:3

    Topics: Adenosine; ADP Ribose Transferases; Animals; Bacterial Toxins; Blood Pressure; Dose-Response Relatio

1993
Maintained endothelium-dependent pulmonary vasodilation following chronic hypoxia in the rat.
    Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 74, Issue:1

    Topics: Air Pressure; Animals; Arginine; Arginine Vasopressin; Calcimycin; Chronic Disease; Endothelium, Vas

1993
Adaptation to chronic hypoxia alters cardiac metabolic response to beta stimulation: novel face of phosphocreatine overshoot phenomenon.
    Journal of molecular and cellular cardiology, 1995, Volume: 27, Issue:8

    Topics: Acclimatization; Adenosine Diphosphate; Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; C

1995
Involvement of protein kinase C in hypoxia-induced desensitization of the beta-adrenergic system in human endothelial cells.
    Biochemical and biophysical research communications, 1996, May-24, Volume: 222, Issue:3

    Topics: Adrenergic beta-Agonists; Cells, Cultured; Down-Regulation; Endothelium, Vascular; Histamine; Humans

1996
Endogenous adenosine increases O2 utilisation efficiency in isoprenaline-stimulated canine myocardium.
    Cardiovascular research, 1996, Volume: 31, Issue:1

    Topics: Adenine; Adenosine; Adenosine Deaminase; Adrenergic beta-Agonists; Animals; Dogs; Hypoxia; Isoproter

1996
Right ventricular infundibular beta-adrenoceptor complex in tetralogy of Fallot patients.
    Pediatric research, 1997, Volume: 42, Issue:1

    Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Child; Child, Preschool; Colforsin; Female; Guanosin

1997
Cardiac beta-adrenergic receptor function in fetal sheep exposed to long-term high-altitude hypoxemia.
    The American journal of physiology, 1997, Volume: 273, Issue:6

    Topics: Adrenergic beta-Agonists; Altitude; Animals; Colforsin; Cyclic AMP; Female; Fetus; Heart; Heart Vent

1997
Membrane potential-dependent and -independent vasodilation in small pulmonary arteries from chronically hypoxic rats.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 285, Issue:3

    Topics: Animals; Body Weight; Cromakalim; Dinoprost; Dose-Response Relationship, Drug; Heart Ventricles; Hem

1998
Influence of beta-adrenoceptor agonists on the pulmonary circulation. Effects of a beta3-adrenoceptor antagonist, SR 59230A.
    European journal of pharmacology, 1998, May-08, Volume: 348, Issue:2-3

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Dose-Response Relationship, Drug; Et

1998
Inter and intra-species-related differences in the regulation of the cardiac autonomic system.
    Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 1998, Volume: 119, Issue:4

    Topics: Altitude; Animals; Autonomic Nervous System; Guinea Pigs; Heart; Heart Rate; Hypoxia; Isoproterenol;

1998
Effect of DMPPO, a phosphodiesterase type 5 inhibitor, on hypoxic pulmonary hypertension in rats.
    British journal of pharmacology, 1998, Volume: 125, Issue:4

    Topics: Allopurinol; Animals; Atrial Natriuretic Factor; Cyclic GMP; Drug Interactions; Hypertension, Pulmon

1998
Sympathetic and respiratory responses to hypoxia in essential hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 1999, Volume: 21, Issue:3

    Topics: Adrenergic beta-Agonists; Adult; Cyclic AMP; Female; Humans; Hypertension; Hypoxia; Isoproterenol; L

1999
Enhanced beta-receptor-mediated vasorelaxation in hypoxic porcine coronary artery.
    The American journal of physiology, 1999, Volume: 277, Issue:4

    Topics: Animals; Arteries; Coronary Vessels; Cyclic AMP; Endothelin-1; Glyburide; Hypoxia; In Vitro Techniqu

1999
Impaired G(s)alpha and adenylyl cyclase cause beta-adrenoceptor desensitization in chronically hypoxic rat hearts.
    American journal of physiology. Cell physiology, 2000, Volume: 279, Issue:5

    Topics: Adenylyl Cyclases; Animals; Calcium; Cardiotonic Agents; Cholera Toxin; Chronic Disease; Colforsin;

2000
Differential alterations in cardiac adrenergic signaling in chronic hypoxia or norepinephrine infusion.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 280, Issue:1

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cholera Toxin; Chroni

2001
Denopamine, a beta(1)-adrenergic agonist, increases alveolar fluid clearance in ex vivo rat and guinea pig lungs.
    Journal of applied physiology (Bethesda, Md. : 1985), 2001, Volume: 90, Issue:1

    Topics: Acute Disease; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Body Fluids; Cells, C

2001
The effects of hypoxia and sleep apnea on isoproterenol sensitivity.
    Sleep, 1998, Nov-01, Volume: 21, Issue:7

    Topics: Adrenergic beta-Agonists; Adult; Cross-Sectional Studies; Electroencephalography; Electromyography;

1998
Beta-adrenoceptors mediate inhibition of lipolysis in adipocytes of tilapia (Oreochromis mossambicus).
    American journal of physiology. Endocrinology and metabolism, 2002, Volume: 282, Issue:2

    Topics: Adipocytes; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adren

2002
cAMP modulation of Ca(2+)-regulated exocytosis in ACh-stimulated antral mucous cells of guinea pig.
    American journal of physiology. Gastrointestinal and liver physiology, 2002, Volume: 282, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Adenosine Tripho

2002
Attenuated "cross talk" between kappa-opioid receptors and beta-adrenoceptors in the heart of chronically hypoxic rats.
    Pflugers Archiv : European journal of physiology, 2002, Volume: 444, Issue:1-2

    Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Calcium Signalin

2002
Effects of alpha adrenergic blockade and tissue catecholamine depletion on pulmonary vascular response to hypoxia.
    The Journal of clinical investigation, 1968, Volume: 47, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Catecholamines; Cattle; Hypoxia; Isoproterenol; Norepinephrin

1968
[Regulation of interrelation between pulmonary ventilation and circulation].
    Kardiologiia, 1975, Volume: 15, Issue:8

    Topics: Animals; Carotid Arteries; Cats; Dihydroergotamine; Ganglionic Blockers; Hypoxia; Isoproterenol; Lun

1975
Factors influencing tolerance of cardiac muscle to hypoxia.
    Recent advances in studies on cardiac structure and metabolism, 1975, Volume: 10

    Topics: Acidosis; Animals; Drug Synergism; Glucose; Glycolysis; Heart; Hydrogen-Ion Concentration; Hypoxia;

1975
Force development of isoproterenol-damaged frog heart muscle in cyanide anoxia.
    Recent advances in studies on cardiac structure and metabolism, 1975, Volume: 8

    Topics: Animals; Anura; Bicarbonates; Cyanides; Heart; Heart Diseases; Hydrogen-Ion Concentration; Hypoxia;

1975
The effects of dopamine and isoproterenol on the pulmonary circulation.
    The Journal of thoracic and cardiovascular surgery, 1976, Volume: 71, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Carbon Dioxide;

1976
Experiments in animals on the pharmacological effects of metipranolol in comparison with propranolol and pindolol.
    Arzneimittel-Forschung, 1977, Volume: 27, Issue:12

    Topics: Adrenergic beta-Antagonists; Animals; Atrial Fibrillation; Cornea; Gluconeogenesis; Heart; Hypoxia;

1977
The influence of hypoxia and hypercapnia on the cardiotoxicity of isoprenaline in dogs [proceedings].
    The Journal of pharmacy and pharmacology, 1978, Volume: 30 Suppl

    Topics: Animals; Dogs; Heart Diseases; Hypercapnia; Hypoxia; Isoproterenol

1978
Determinants of hypoxic contracture in isolated heart muscle preparations.
    Cardiovascular research, 1979, Volume: 13, Issue:2

    Topics: Animals; Anura; Caffeine; Calcium; Cats; Hydrogen-Ion Concentration; Hypoxia; In Vitro Techniques; I

1979
Restoration of slow responses in hypoxic heart muscle by alkaline pH.
    Journal of molecular and cellular cardiology, 1979, Volume: 11, Issue:9

    Topics: Animals; Guinea Pigs; Hydrogen-Ion Concentration; Hypoxia; In Vitro Techniques; Isoproterenol; Membr

1979
[Electrophysiologic aspects of the hypoxic and ischemic myocardium].
    Arquivos brasileiros de cardiologia, 1979, Volume: 32, Issue:6

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Calcium; Coronary Disease; Guinea Pigs; Heart; Hyd

1979
The influence of arterial pH control on the cardiotoxicity of isoprenaline in hypoxic dogs [proceedings].
    The Journal of pharmacy and pharmacology, 1979, Volume: 31 Suppl

    Topics: Animals; Arteries; Blood Chemical Analysis; Dogs; Heart Diseases; Hydrogen-Ion Concentration; Hypoxi

1979
Glycogenolysis and control of anaphylactic histamine release by cyclic adenosine monophosphate--related agents.
    The Journal of allergy and clinical immunology, 1975, Volume: 56, Issue:4

    Topics: Anaphylaxis; Animals; Antigen-Antibody Reactions; Cyclic AMP; Glucose; Glycogen; Guinea Pigs; Histam

1975
Spectrum analysis of transient phenomena of the left ventricular pressure.
    Archives internationales de physiologie et de biochimie, 1978, Volume: 86, Issue:1

    Topics: Animals; Aorta; Carotid Arteries; Dogs; Heart Rate; Heart Ventricles; Hypoxia; Isoproterenol; Myocar

1978
The effect of isoproterenol on hypoxia-mediated histamine release.
    Annals of allergy, 1979, Volume: 43, Issue:3

    Topics: Animals; Guinea Pigs; Histamine; Histamine Release; Hypoxia; Isoproterenol; Nitrogen; Oxygen

1979
Attenuation of beta-adrenergic cardiac responses in chronically hypoxic rats with right ventricular hypertrophy.
    Recent advances in studies on cardiac structure and metabolism, 1975, Volume: 7

    Topics: Animals; Cardiomegaly; Erythrocyte Count; Heart; Heart Ventricles; Hematocrit; Hemoglobins; Hypoxia;

1975
The release of adenosine 3':5'-cyclic monophosphate from the isolated perfused rat heart.
    The Biochemical journal, 1975, Volume: 152, Issue:2

    Topics: Animals; Cyclic AMP; Heart; Hypoxia; Isoproterenol; Male; Myocardium; Perfusion; Rats

1975
The role of cyclic adenosine 3', 5'-monophosphate and calcium in the regulation of contractility and glycogen phosphorylase activity in guinea pig papillary muscle.
    Circulation research, 1976, Volume: 39, Issue:3

    Topics: Animals; Calcium; Catecholamines; Cyclic AMP; Electric Stimulation; Enzyme Activation; Guinea Pigs;

1976
Changes in sensitivity to anoxia of the cardiac action potential plateau during chick embryonic development.
    Developmental biology, 1977, Jul-01, Volume: 58, Issue:1

    Topics: Action Potentials; Age Factors; Aminophylline; Animals; Bucladesine; Calcium; Chick Embryo; Glucose;

1977
Reduction by adenosine of the isoproterenol-induced increase in cyclic adenosine 3',5'-monophosphate formation and glycogen phosphorylase activity in rat heart muscle.
    Circulation research, 1978, Volume: 43, Issue:5

    Topics: Adenosine; Adenosine Deaminase; Animals; Cyclic AMP; Glycogen; Hypoxia; Isoproterenol; Myocardium; P

1978
Thyrotoxicosis: comparison of effects of thyroid ablation and beta-adrenergic blockade on metabolic rate and ventilatory control.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 46, Issue:3

    Topics: Adult; Basal Metabolism; Carbon Dioxide; Female; Heart Rate; Humans; Hyperthyroidism; Hypoxia; Iodin

1978
Cardiovascular responsiveness to beta-adrenergic stimulation and blockade in chronic hypoxia.
    The American journal of physiology, 1975, Volume: 228, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atmospheric Pressure; Blood Pressure

1975
The effect of beta-adrenergic agonists on enzyme release from the hypoxic isolated perfused rat heart.
    Biochemical Society transactions, 1975, Volume: 3, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Catecholamines; Creatine Kinase; Heart; Heart Rate; Hypoxia; In V

1975
Cardiovascular effects of epidural analgesia. I. Thoracic epidural analgesia. An experimental study in sheep of the effects on central circulation, regional perfusion and myocardial performance during normoxia, hypoxia and isoproterenol administration.
    Acta anaesthesiologica Scandinavica. Supplementum, 1978, Volume: 69

    Topics: Anesthesia, Epidural; Animals; Blood Circulation; Blood Gas Analysis; Blood Pressure; Cardiac Output

1978
Cardiac prostacyclin release: stimulation by hypoxia and various agents.
    Scandinavian journal of haematology. Supplementum, 1979, Volume: 34

    Topics: Adenosine Diphosphate; Animals; Epoprostenol; Heart; Humans; Hypoxia; Indomethacin; Isoproterenol; M

1979
Venous admixture in human septic shock: comparative effects of blood volume expansion, dopamine infusion and isoproterenol infusion on mismatching of ventilation and pulmonary blood flow in peritonitis.
    Circulation, 1979, Volume: 60, Issue:1

    Topics: Adult; Aged; Blood Pressure; Carbon Dioxide; Dopamine; Humans; Hypoxia; Isoproterenol; Middle Aged;

1979
Depression of hypoxic pulmonary vasoconstriction in the dog by dopamine and isoprenaline.
    British journal of anaesthesia, 1979, Volume: 51, Issue:4

    Topics: Animals; Depression, Chemical; Dogs; Dopamine; Dose-Response Relationship, Drug; Hypoxia; Isoprotere

1979
[Biochemical changes in myocardial homogenate from rats under isoproterenol with and without previously administration of propranolol (author's transl)].
    Archivos de farmacologia y toxicologia, 1979, Volume: 5, Issue:1

    Topics: Animals; Female; Hypoxia; Isoproterenol; Myocardium; Propranolol; Rats

1979
Mechanism of the attenuated cardiac response to beta-adrenergic stimulation in chronic hypoxia.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1978, Volume: 44, Issue:5

    Topics: Altitude; Animals; Atropine; Catechol O-Methyltransferase; Heart Rate; Hypoxia; Isoproterenol; Monoa

1978
Isoproterenol as a potential pulmonary vasodilator in primary pulmonary hypertension.
    The American journal of cardiology, 1978, Volume: 42, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Azathioprine; Cardiac Catheterization; Cardiac Output; Diph

1978
Neonatal and pediatric cardiovascular crises.
    JAMA, 1975, Apr-14, Volume: 232, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Bradycardia; Cardiovascular Diseases; Digoxin; Emerge

1975
Hemodynamics and myocardial function during acute hypoxia in the pony.
    American journal of veterinary research, 1977, Volume: 38, Issue:3

    Topics: Animals; Blood Pressure; Carbon Dioxide; Cardiac Output; Female; Heart; Heart Rate; Hemodynamics; Ho

1977
Reduced extrarenal erythropoietin production in rats treated with isoproterenol.
    Experimental hematology, 1977, Volume: 5, Issue:3

    Topics: Age Factors; Anemia; Animals; Erythropoiesis; Erythropoietin; Hypoxia; Injections, Intraperitoneal;

1977
Cardiac muscle function during and after hypoxia: effects of glucose concentration, mannitol and isoproternol.
    Journal of molecular and cellular cardiology, 1976, Volume: 8, Issue:8

    Topics: Animals; Glucose; Hypoxia; In Vitro Techniques; Iodoacetates; Isoproterenol; Male; Mannitol; Myocard

1976
The release of a coronary vasodilator metabolite from the guinea-pig isolated perfused heart stimulated by catecholamines, histamine and electrical pacing and by exposure to anoxia.
    British journal of pharmacology, 1976, Volume: 58, Issue:1

    Topics: Animals; Catecholamines; Electric Stimulation; Epinephrine; Female; Guinea Pigs; Heart; Histamine; H

1976
Nonsustained pulmonary vasoconstriction during acute hypoxia in anesthetized dogs.
    The American journal of physiology, 1975, Volume: 228, Issue:3

    Topics: Animals; Blood Pressure; Carbon Dioxide; Cardiac Output; Dogs; Heart Rate; Hypoxia; Indomethacin; Is

1975
The effect of anoxia on the ventricular fibrillation threshold in the rabbit isolated heart.
    British journal of pharmacology, 1975, Volume: 54, Issue:4

    Topics: Adenosine; Animals; Dipyridamole; Electrocardiography; Heart; Heart Rate; Hypoxia; In Vitro Techniqu

1975
Experimental cardiac necrosis in hypobaric and anemic hypoxia.
    Journal of applied physiology, 1975, Volume: 39, Issue:2

    Topics: Anemia, Hypochromic; Animals; Atmosphere Exposure Chambers; Hemoglobins; Hypoxia; Injections, Subcut

1975
[Isoprenaline and hypoxemia in refractary shock].
    Revista espanola de anestesiologia y reanimacion, 1975, Volume: 22, Issue:5

    Topics: Adult; Humans; Hypoxia; Isoproterenol; Perfusion; Respiratory Function Tests; Shock, Traumatic; Time

1975
[Intensive acre and resuscitation in bronchial asthma and the asthmatic state].
    Terapevticheskii arkhiv, 1975, Volume: 47, Issue:8

    Topics: Acidosis; Adolescent; Adult; Aminophylline; Anesthesia; Asthma; Critical Care; Droperidol; Ephedrine

1975
Transmural metabolic gradients of the canine left ventricle in coronary constriction, systemic hypoxia, hemorrhagic shock, and isoproterenol infusion.
    Recent advances in studies on cardiac structure and metabolism, 1975, Volume: 6

    Topics: Adenine Nucleotides; Animals; Cardiomyopathies; Coronary Disease; Dogs; Hypoxia; Isoproterenol; Lact

1975
Time-dependent changes of collateral coronary reactivity in the dog.
    Recent advances in studies on cardiac structure and metabolism, 1975, Volume: 10

    Topics: Animals; Catecholamines; Collateral Circulation; Coronary Circulation; Dogs; Female; Hypoxia; Isopro

1975
Beta adrenergic receptor dysfunction in hypoxic inhibition of insulin release.
    Endocrinology, 1976, Volume: 98, Issue:2

    Topics: Animals; Blood Glucose; Carbon Dioxide; Dogs; Epinephrine; Glucose; Hypoxia; Insulin; Insulin Secret

1976
Prolongation of tension on reoxygenation following myocardial hypoxia: a possible role for mitochondria in muscle relaxation.
    Journal of molecular and cellular cardiology, 1976, Volume: 8, Issue:3

    Topics: Animals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Dinitrophenols; Glycolysis; Heart; Hypoxia; Insu

1976
Adrenergic system in high altitude residents.
    International journal of sports medicine, 1992, Volume: 13 Suppl 1

    Topics: Adult; Altitude; Bolivia; Chronic Disease; Heart Rate; Humans; Hypoxia; Infusions, Intravenous; Isop

1992
Effects of ibutilide fumarate, a novel antiarrhythmic agent, and its enantiomers on isolated rabbit myocardium.
    European journal of pharmacology, 1992, Nov-03, Volume: 222, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Fema

1992
Evidence that epithelium-dependent relaxation of vascular smooth muscle detected by co-axial bioassays is not attributable to hypoxia.
    British journal of pharmacology, 1992, Volume: 105, Issue:4

    Topics: Animals; Aorta; Benzopyrans; Biological Assay; Biological Factors; Cromakalim; Epithelium; Glyburide

1992
Interaction of catecholamine and acetazolamide in the action on the endolymphatic sac direct current potential.
    Acta oto-laryngologica, 1992, Volume: 112, Issue:1

    Topics: Acetazolamide; Action Potentials; Animals; Disease Models, Animal; Drug Synergism; Endolymphatic Sac

1992
Cytosolic free magnesium in stimulated, hypoxic, and underperfused rat heart.
    Journal of molecular and cellular cardiology, 1991, Volume: 23, Issue:9

    Topics: Adenosine Triphosphate; Animals; Coronary Disease; Cytosol; Hydrogen-Ion Concentration; Hypoxia; In

1991
[The effect of adaptation to stress exposures and to periodic hypoxia on the cardiomyocyte trigger activity of the papillary muscles in the rat].
    Biulleten' eksperimental'noi biologii i meditsiny, 1991, Volume: 112, Issue:11

    Topics: Action Potentials; Adaptation, Physiological; Animals; Atmosphere Exposure Chambers; Electric Stimul

1991
Comparative circulatory effects of isoproterenol and dopamine in lambs with experimental cyanotic heart disease.
    Pediatric research, 1991, Volume: 29, Issue:4 Pt 1

    Topics: Animals; Animals, Newborn; Cardiac Output; Dopamine; Heart Defects, Congenital; Hemodynamics; Hypoxi

1991
Prostacyclin production and mediation of adenylate cyclase activity in the pulmonary artery. Alterations after prolonged hypoxia in the rat.
    The Journal of clinical investigation, 1991, Volume: 88, Issue:2

    Topics: Adenylyl Cyclases; Animals; Endothelium, Vascular; Enzyme Activation; Epoprostenol; Guanosine Tripho

1991
Effects of isoprenaline, adrenaline and selective alpha 1- and alpha 2- adrenoceptor stimulation on hypoxic pulmonary vasoconstriction in rat isolated perfused lungs.
    Pulmonary pharmacology, 1990, Volume: 3, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Epinephrine; Female; Hypoxia; In V

1990
Effect of nitroglycerin and a nitroglycerin-like substance in isoprenaline (ISO) necrosis and hypoxia.
    Acta physiologica Hungarica, 1990, Volume: 75 Suppl

    Topics: Animals; Hypoxia; Isoproterenol; Molsidomine; Necrosis; Nitroglycerin; Rats

1990
Superoxide anion inhibits cGMP-associated bovine pulmonary arterial relaxation.
    The American journal of physiology, 1990, Volume: 259, Issue:4 Pt 2

    Topics: Aminoquinolines; Animals; Anions; Cattle; Cyclic GMP; Ditiocarb; Hydrogen Peroxide; Hypoxia; Isoprot

1990
Hypoxia-induced vasodilation of the feline superior mesenteric artery is not adenosine mediated.
    The American journal of physiology, 1990, Volume: 259, Issue:4 Pt 1

    Topics: Adenosine; Animals; Cats; Hypoxia; Isoproterenol; Mesenteric Arteries; Oxygen; Partial Pressure; Rec

1990
Adenosine formation and energy metabolism: a 31P-NMR study in isolated rat heart.
    The American journal of physiology, 1990, Volume: 258, Issue:3 Pt 2

    Topics: Adenosine; Adenosine Deaminase; Animals; Coronary Circulation; Cytosol; Energy Metabolism; Hypoxia;

1990
Autonomic regulation of the pulmonary circulation.
    Journal of cardiovascular pharmacology, 1985, Volume: 7 Suppl 3

    Topics: Acetylcholine; Animals; Autonomic Nervous System; Blood Pressure; Cats; Dobutamine; Dopamine; Electr

1985
Cardiac electrophysiological effects of isoprenaline, phenylephrine, and noradrenaline on normal and mildly "ischaemic" sheep Purkinje fibers.
    Journal of cardiovascular pharmacology, 1989, Volume: 13, Issue:2

    Topics: Acidosis; Action Potentials; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cor

1989
Endothelium-dependent relaxation and cyclic GMP accumulation in rabbit pulmonary artery are selectively impaired by moderate hypoxia.
    Circulation research, 1989, Volume: 65, Issue:6

    Topics: Adenosine Triphosphate; Animals; Calcimycin; Cyclic GMP; Endothelium, Vascular; Hypoxia; Isoproteren

1989
Adenosine production and energy metabolism in ischaemic and metabolically stimulated rat heart.
    Journal of molecular and cellular cardiology, 1989, Volume: 21, Issue:11

    Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Allosteric Regulation; Animals; Coronary Circulatio

1989
Metabolic-membrane coupling in red blood cells of trout: the effects of anoxia and adrenergic stimulation.
    The Journal of experimental biology, 1989, Volume: 143

    Topics: Aerobiosis; Amiloride; Anaerobiosis; Animals; Energy Metabolism; Erythrocyte Membrane; Erythrocytes;

1989
Beta-adrenergic influence on increased myocardial oxygen consumption during hypoxemia in awake newborn lambs.
    Pediatric research, 1989, Volume: 25, Issue:6

    Topics: Animals; Animals, Newborn; Heart; Hypoxia; Isoproterenol; Myocardium; Oxygen Consumption; Propranolo

1989
Reversal of hypoxia-induced decrease in human cardiac response to isoproterenol infusion.
    Journal of applied physiology (Bethesda, Md. : 1985), 1989, Volume: 67, Issue:2

    Topics: Adult; Blood Pressure; Heart; Heart Rate; Hemodynamics; Humans; Hypoxia; Isoproterenol; Male; Norepi

1989
The effect of hypoxia on the phosphorylation of contractile and other proteins in perfused rat heart challenged by isoprenaline.
    Biomedica biochimica acta, 1987, Volume: 46, Issue:5

    Topics: Animals; Calcium; Catecholamines; Contractile Proteins; Cyclic AMP; Heart; Hypoxia; In Vitro Techniq

1987
Inhibition by simulated ischemia or hypoxia of delayed afterdepolarizations provoked by cyclic AMP: significance for ischemic and reperfusion arrhythmias.
    Journal of molecular and cellular cardiology, 1988, Volume: 20, Issue:2

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Bucladesine; Coronary Disease; Cyclic AMP; Electri

1988
Decreased cardiac response to isoproterenol infusion in acute and chronic hypoxia.
    Journal of applied physiology (Bethesda, Md. : 1985), 1988, Volume: 65, Issue:5

    Topics: Acute Disease; Adult; Chronic Disease; Female; Heart Rate; Humans; Hypoxia; Infusions, Intravenous;

1988
Influence of temperature and cyanide on electrical and mechanical activities of isoproterenol-damaged frog heart.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1985, Volume: 81, Issue:1

    Topics: Action Potentials; Animals; Cyanides; Electric Conductivity; Electric Stimulation; Female; Heart; Hy

1985
Stimulation of fetal breathing activity by beta-adrenergic mechanisms.
    Journal of applied physiology (Bethesda, Md. : 1985), 1986, Volume: 60, Issue:6

    Topics: Adrenergic beta-Agonists; Animals; Biomechanical Phenomena; Carotid Sinus; Denervation; Epinephrine;

1986
Increase and regression of the protective effect of high altitude acclimatization on the isoprenaline-induced necrotic lesions in the rat myocardium.
    Physiologia Bohemoslovaca, 1987, Volume: 36, Issue:1

    Topics: Acclimatization; Adipose Tissue; Altitude; Animals; Body Weight; Drug Resistance; Eating; Heart; Hyp

1987
Role of beta adrenergic receptors in carotid body function of the goat.
    Respiration physiology, 1986, Volume: 64, Issue:2

    Topics: Anesthesia; Animals; Carotid Body; Chemoreceptor Cells; Denervation; Goats; Hypoxia; Isoproterenol;

1986
Adrenergic and local control of O2 uptake during and after severe hypoxia.
    Journal of applied physiology (Bethesda, Md. : 1985), 1986, Volume: 61, Issue:5

    Topics: Animals; Dogs; Hindlimb; Hypoxia; Isoproterenol; Methoxamine; Muscles; Oxygen Consumption; Receptors

1986
The coronary vasodilator mediator released by hypoxia and isoprenaline is not affected by cyclo-oxygenase inhibition.
    Prostaglandins, 1986, Volume: 31, Issue:2

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Coronary Vessels; Female; Guinea Pigs; Heart; Heart Tr

1986
Effects of arterial hypoxia and isoproterenol on in vitro postnatal intestinal circulation.
    The American journal of physiology, 1988, Volume: 255, Issue:5 Pt 2

    Topics: Aging; Animals; Animals, Newborn; Hypoxia; Intestines; Isoproterenol; Jejunum; Oxygen Consumption; R

1988
Separation of rate of left ventricular relaxation from chamber stiffness in rats.
    The American journal of physiology, 1988, Volume: 255, Issue:6 Pt 2

    Topics: Animals; Blood Pressure; Caffeine; Heart Ventricles; Hypoxia; Isoproterenol; Male; Myocardial Contra

1988
Carbon monoxide poisoning at a lowered myocardial adaptation capacity: animal ECG models.
    Activitas nervosa superior, 1988, Volume: 30, Issue:4

    Topics: Adaptation, Physiological; Animals; Carbon Monoxide Poisoning; Cardiomyopathies; Cholesterol; Electr

1988
Effects of metabolic inhibition on ion transport by dog bronchial epithelium.
    Journal of applied physiology (Bethesda, Md. : 1985), 1988, Volume: 64, Issue:1

    Topics: Absorption; Animals; Biological Transport; Bronchi; Cell Membrane Permeability; Cyanides; Dogs; Epit

1988
Neonatal nutritional deprivation or enhancement: the cardiac-sympathetic axis and its role in cardiac growth and stress responses.
    Pediatric research, 1988, Volume: 23, Issue:4

    Topics: Age Factors; Animals; Animals, Newborn; Female; Heart; Hydralazine; Hypoxia; Isoproterenol; Male; My

1988
Augmentation of cardiac output with intravenous catecholamines in unanesthetized hypoxemic newborn lambs.
    Pediatric research, 1987, Volume: 22, Issue:6

    Topics: Animals; Animals, Newborn; Blood Pressure; Cardiac Output; Catecholamines; Dobutamine; Dopamine; Hea

1987
Interstitial fluid of isolated perfused rat hearts: glucose and lactate concentration.
    Journal of molecular and cellular cardiology, 1987, Volume: 19, Issue:2

    Topics: Animals; Capillary Permeability; Coronary Circulation; Extracellular Space; Glucose; Heart Rate; Hyp

1987
Effects of anoxia and ischemia on uptake2 of catecholamines in perfused rat heart.
    European journal of pharmacology, 1987, Sep-11, Volume: 141, Issue:2

    Topics: Animals; Catechol O-Methyltransferase; Catecholamines; Coronary Disease; Hypoxia; In Vitro Technique

1987
Studies on the calcium antagonistic action of tetrandrine: XIII. Protective effect of tetrandrine on myocardial hypoxia and necrosis induced by isoproterenol in rats.
    Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 1986, Volume: 6, Issue:1

    Topics: Alkaloids; Animals; Benzylisoquinolines; Calcium Channel Blockers; Coronary Disease; Electrocardiogr

1986
[Effect of strophanthin, digoxin and isoproterenol on heart contractility in hypoxia and hypercapnic acidosis].
    Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 1986, Volume: 6, Issue:4

    Topics: Acidosis, Respiratory; Animals; Cymarine; Digoxin; Guinea Pigs; Heart; Hypoxia; In Vitro Techniques;

1986
Adrenergic mechanisms in oxygen chemoreception in the cat aortic body.
    Respiration physiology, 1986, Volume: 63, Issue:3

    Topics: Animals; Aortic Bodies; Biomechanical Phenomena; Cats; Chemoreceptor Cells; Female; Hypotension; Hyp

1986
Effects of ouabain, low K+, and aldosterone on hypoxic pressor reactivity of rat lungs.
    The American journal of physiology, 1985, Volume: 248, Issue:1 Pt 2

    Topics: Aldosterone; Angiotensin II; Animals; Dose-Response Relationship, Drug; Hypoxia; In Vitro Techniques

1985
Comparison of erythropoietic response to erythropoietin-secreting stimuli in mice following polycythemia induced by transfusion or hypoxia.
    Experimental hematology, 1985, Volume: 13, Issue:3

    Topics: Animals; Blood Transfusion; Dexamethasone; Erythrocyte Volume; Erythrocytes; Erythropoiesis; Erythro

1985
The effect of isoproterenol on the development and recovery of hypoxic pulmonary hypertension. A structural and hemodynamic study.
    The American journal of pathology, 1985, Volume: 121, Issue:1

    Topics: Animals; Heart; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Isoproterenol; Lung; Lung Volume Mea

1985
Acute myocardial histopathology in normal and arteriosclerotic rats during isoproterenol-induced infarction.
    British journal of experimental pathology, 1970, Volume: 51, Issue:6

    Topics: Acidosis; Animals; Arteriosclerosis; Female; Hypoxia; Isoproterenol; Male; Myocardial Infarction; My

1970
Adrenergic mechanisms in the cerebral vascular bed.
    Experientia, 1973, Jun-15, Volume: 29, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Blood Flow Velocity; Blood Pressure; Brac

1973
[Hypoxic pulmonary vascular constriction. I. Effects of beta-adrenergic receptor stimulation and blockade].
    Kokyu to junkan. Respiration & circulation, 1973, Volume: 21, Issue:7

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cats; Hypoxia; Isoproterenol; Propra

1973
[Differentiation between real and apparent beta receptor blockade in the heart].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:3

    Topics: Adenosine; Adrenergic beta-Antagonists; Animals; Electrocardiography; Glycogen; Heart; Heart Rate; H

1974
Effect of acetaldehyde on the isolated, non-working guinea-pig heart: independence of the coronary flow increase from changes in heart rate and oxygen consumption.
    Canadian journal of physiology and pharmacology, 1974, Volume: 52, Issue:3

    Topics: Acetaldehyde; Acetates; Animals; Atropine; Coronary Circulation; Epinephrine; Ethanol; Guinea Pigs;

1974
Influence of reserpine and of adrenolytic agents on the pulmonary arterial pressor response to hypoxia and catecholamines.
    Archives internationales de physiologie et de biochimie, 1964, Volume: 72, Issue:3

    Topics: Animals; Blood Pressure; Cats; Hypoxia; Isoproterenol; Norepinephrine; Phentolamine; Pulmonary Circu

1964
Isoprenaline and practolol.
    Lancet (London, England), 1970, Feb-07, Volume: 1, Issue:7641

    Topics: Animals; Arrhythmias, Cardiac; Hypoxia; Isoproterenol; Male; Rats

1970
Fibrinolytic responses under alterations of acid-base balance and hypoxia.
    The Journal of trauma, 1974, Volume: 14, Issue:9

    Topics: Acidosis; Acidosis, Respiratory; Animals; Blood Coagulation; Dogs; Dose-Response Relationship, Drug;

1974
The growth of the muscular and collagenous parts of the rat heart in various forms of cardiomegaly.
    The Journal of physiology, 1969, Volume: 200, Issue:2

    Topics: Anemia, Hypochromic; Animals; Cardiomegaly; Collagen; Hydroxyproline; Hypertension; Hypertrophy; Hyp

1969
Effect of catecholamines on resistance of the myocardium to anoxia and on the heart glycogen concentration.
    Physiologia Bohemoslovaca, 1968, Volume: 17, Issue:1

    Topics: Animals; Catecholamines; Epinephrine; Glycogen; Heart; Heart Ventricles; Hypoxia; Isoproterenol; Mal

1968
Effects of manganese, glucose and isoprenaline on the action potential of anoxic ventricular muscle.
    Naunyn-Schmiedeberg's archives of pharmacology, 1972, Volume: 275, Issue:2

    Topics: Action Potentials; Animals; Glucose; Guinea Pigs; Heart; Heart Ventricles; Hypoxia; Isoproterenol; M

1972
[Studies of hypoxia. II. Pressor behavior and pressor response to nor-adrenaline, pitressin, hypertensin, isoprenaline and acetylcholine in hypoxia caused by decreased pulmonary ventilation].
    Bollettino della Societa italiana di biologia sperimentale, 1967, Mar-31, Volume: 43, Issue:6

    Topics: Acetylcholine; Angiotensin II; Animals; Blood Pressure; Dogs; Hypoxia; Isoproterenol; Norepinephrine

1967
Histochemical study of effects of hypoxia and isoproterenol on rat myocardium.
    The American journal of cardiology, 1968, Volume: 22, Issue:3

    Topics: Animals; Atmospheric Pressure; Electron Transport Complex IV; Glutamate Dehydrogenase; Heart; Histoc

1968
Role of lysosomal enzymes in adaptation to simulated high altitude by myocardium subject to the effects of acute aortic stenosis or isoproterenol.
    Journal of molecular and cellular cardiology, 1971, Volume: 2, Issue:3

    Topics: Adaptation, Physiological; Altitude; Animals; Aortic Coarctation; Aortic Valve Stenosis; Deoxyribonu

1971
The application of the cytophotometer to the study of metabolic transitions of isolated rat heart.
    Cardiology, 1972, Volume: 57, Issue:1

    Topics: Animals; Blood Pressure; Fluorometry; Food Deprivation; Glucose; Heart; Hypoxia; Isoproterenol; Meth

1972
[Effect of hypoxia and vasoactive drugs on regional myocardial blood flow].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1972, Volume: 9, Issue:6

    Topics: Angiotensin II; Animals; Blood Pressure; Coronary Circulation; Dogs; Hypoxia; Isoproterenol; Norepin

1972
Effect of increased aortic perfusion pressure on fluorescent emission of the isolated rat heart.
    Journal of molecular and cellular cardiology, 1974, Volume: 6, Issue:2

    Topics: Animals; Aorta; Blood Flow Velocity; Blood Pressure; Coronary Vessels; Fluorescence; Glucose; Heart

1974
[The biological activities of cytochrome c hemeoctapeptide (CHP). (2). The effects of CHP against the tissue damage caused by dl-isoproterenol-induced cardiac infarct-like angina (author's transl)].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1974, Volume: 94, Issue:1

    Topics: Angina Pectoris; Animals; Aspartate Aminotransferases; Cytochrome c Group; Heart; Hemeproteins; Hypo

1974
[Experimental models for circulatory failure in hyperthermia under conditions of septic shock. Pressor reactions at various temperatures].
    Zeitschrift fur experimentelle Chirurgie, 1974, Volume: 7, Issue:4

    Topics: Angiotensin II; Animals; Blood Pressure; Dogs; Electric Stimulation; Epinephrine; Fever; Hypoxia; Is

1974
Cardiopulmonary function during adrenergic beta receptor blockade.
    Cor et vasa, 1965, Volume: 7, Issue:4

    Topics: Animals; Blood Circulation; Dogs; Epinephrine; Ethanolamines; Heart; Hypoxia; Isoproterenol; Respira

1965
The action of adrenergic beta-receptor blocking agents on susceptibility to cardiac arrhythmias in hypothermia and hypoxia.
    Experientia, 1965, Dec-15, Volume: 21, Issue:12

    Topics: Animals; Cats; Ethanolamines; Hypothermia, Induced; Hypoxia; Isoproterenol; Propranolol; Sympatholyt

1965
[Effects of 6-hydroxy-6-methyl-2-heptamine (Heptamine) on the isolated rabbit atria].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1967, Nov-20, Volume: 63, Issue:6

    Topics: Amines; Animals; Bretylium Compounds; Cardiac Glycosides; Epinephrine; Ethanol; Heart Atria; Heart R

1967
Evolution of epinephrine responses of hypoxic rabbit aortic muscle.
    The American journal of physiology, 1969, Volume: 216, Issue:6

    Topics: Animals; Aorta; Epinephrine; Hypoxia; Isoproterenol; Muscle Contraction; Muscle, Smooth; Oxygen; Phe

1969
Some cardiac effects of beta-adrenergic stimulants in animals.
    Postgraduate medical journal, 1971, Volume: 47

    Topics: Adrenergic beta-Agonists; Aerosols; Amino Alcohols; Animals; Bronchodilator Agents; Dogs; Heart; Hyp

1971
Effect of glucose in isoproterenol-induced necrotic heart under anoxic perfusion.
    Japanese journal of pharmacology, 1974, Volume: 24, Issue:5

    Topics: Adenosine Triphosphate; Animals; Glucose; Glycogen; Heart; Heart Diseases; Hypoxia; Isoproterenol; L

1974
[Hemodynamic studies with isoprenaline and beta adrenergic receptor blockaders in children with tetralogy of Fallot].
    Zeitschrift fur Kreislaufforschung, 1972, Volume: 61, Issue:1

    Topics: Adolescent; Allyl Compounds; Amino Alcohols; Blood Pressure; Cardiac Catheterization; Child; Child,

1972
The independence of pulmonary shunting and pulmonary edema.
    Surgery, 1973, Volume: 74, Issue:2

    Topics: Antipyrine; Cardiac Catheterization; Cardiac Surgical Procedures; Chemotherapy, Cancer, Regional Per

1973
Successful orthotopic transplantation of the canine liver after prolonged preservation by initial perfusion and cold storage.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1973, Volume: 5, Issue:4

    Topics: Animals; Antifibrinolytic Agents; Azathioprine; Catheterization; Dogs; Graft Rejection; Hemorrhagic

1973
The effect of isoproterenol and Collins' solution on the preservation of canine livers with simple cooling.
    Transplantation proceedings, 1974, Volume: 6, Issue:3

    Topics: Adenine Nucleotides; Animals; Cell Membrane; Cold Temperature; Dogs; Extracellular Space; Hypoxia; I

1974
Potentiation of the contractile effects of norepinephrine by hypoxia.
    The Journal of clinical investigation, 1972, Volume: 51, Issue:9

    Topics: Animals; Aorta; Blood Flow Velocity; Blood Pressure; Carbon Dioxide; Coronary Circulation; Dogs; Ele

1972
The effects of aminophylline on the increased myocardial blood flow produced by systemic hypoxia or by coronary artery occlusion.
    European journal of pharmacology, 1972, Volume: 20, Issue:1

    Topics: Adenosine; Aminophylline; Animals; Blood Flow Velocity; Cats; Coronary Disease; Coronary Vessels; Hy

1972
Augmentation of chemosensitivity during mild exercise in normal man.
    Journal of applied physiology, 1972, Volume: 33, Issue:6

    Topics: Adult; Carbon Dioxide; Carotid Body; Chemoreceptor Cells; Heart Rate; Humans; Hypoxia; Isoproterenol

1972
Pulmonary artery wedge pressure lability in the bovine.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 141, Issue:3

    Topics: Animals; Blood Pressure; Carotid Arteries; Catheterization; Cattle; Cattle Diseases; Electrocardiogr

1972
[Anoxic tolerance of heart function and electrolyte distribution in the myocardium of isoprenaline-resistant rats].
    Acta biologica et medica Germanica, 1972, Volume: 29, Issue:3

    Topics: Animals; Death; Electrocardiography; Extracellular Space; Heart; Hypoxia; Isoproterenol; Male; Myoca

1972
[Study by means of microcatheterization of the activity of drugs with pharmacodynamic effect on the average pressure in the pulmonary artery].
    Le Poumon et le coeur, 1972, Volume: 28, Issue:6

    Topics: Adult; Aged; Amino Alcohols; Blood Pressure; Bronchodilator Agents; Cardiac Catheterization; Female;

1972
The pre-ejection period of the fetal heart: response to stress in the term fetal lamb.
    American journal of obstetrics and gynecology, 1973, Feb-01, Volume: 115, Issue:3

    Topics: Animals; Blood Pressure; Carbon Dioxide; Cardiac Output; Carotid Arteries; Electrocardiography; Fema

1973
Effects of dopamine on myocardial metabolism in patients with ischaemic heart disease.
    Cardiovascular research, 1973, Volume: 7, Issue:4

    Topics: Adult; Angiography; Blood Glucose; Blood Pressure; Calcium; Cardiac Output; Coronary Disease; Dopami

1973
Use of hepatic cell membrane potential measurement to evaluate new method of liver preservation.
    Surgery, 1973, Volume: 74, Issue:4

    Topics: Acid Phosphatase; Alanine Transaminase; Animals; Aspartate Aminotransferases; Cell Membrane; Cell Me

1973
Spleen as an experimental model for the study of vascular capacitance.
    The American journal of physiology, 1973, Volume: 225, Issue:6

    Topics: Acetylcholine; Animals; Atropine; Autonomic Agents; Blood Pressure; Blood Vessels; Dogs; Electric St

1973
Resuscitation and immediate care of the critically ill and injured patient.
    Seminars in drug treatment, 1973,Winter, Volume: 3, Issue:3

    Topics: Accidents; Acid-Base Equilibrium; Airway Obstruction; Anti-Arrhythmia Agents; Blood Transfusion; Car

1973
Experimental studies on the pulmonary edema investigation with special reference to permeability of the pulmonary capillary from the standpoint of pulmonary lymphatic return.
    Japanese circulation journal, 1973, Volume: 37, Issue:11

    Topics: Animals; Blood Pressure; Capillary Permeability; Dogs; Epinephrine; Heart Rate; Hypoxia; Isoproteren

1973
[Changes in fetal acidosis after administration of beta-mimetics during labor].
    Annali di ostetricia, ginecologia, medicina perinatale, 1973, Volume: 94, Issue:5

    Topics: Acidosis; Adult; Female; Fetal Diseases; Humans; Hypoxia; Isoproterenol; Labor, Obstetric; Metaprote

1973
The demonstration of energy dependence of the isoproterenol-induced transcellular Ca2+ current in isolated perfused guinea pig hearts--an explanation for mechanical failure of ischemic myocardium.
    The Journal of surgical research, 1974, Volume: 16, Issue:4

    Topics: Action Potentials; Animals; Biological Transport; Caffeine; Calcium; Cell Membrane; Cell Membrane Pe

1974
The pharmacologic management of status asthmaticus in children.
    Pediatrics, 1974, Volume: 54, Issue:2

    Topics: Aerosols; Aminophylline; Anti-Bacterial Agents; Asthma; Betamethasone; Buffers; Child; Child, Presch

1974
[Myocardial necrosis induced with isoproterenol in rat heart].
    Acta pharmaceutica Hungarica, 1974, Volume: 44, Issue:1

    Topics: Animals; Carbon Radioisotopes; Heart; Hypoxia; Isoproterenol; Myocardial Infarction; Myocardium; Nec

1974
Effects of isoproterenol on contractile function of the ischemic and anoxic heart.
    The American journal of physiology, 1974, Volume: 227, Issue:2

    Topics: Animals; Coronary Disease; Heart; Hypoxia; Isoproterenol; Male; Myocardium; Oxygen Consumption; Pres

1974
Further observations on the cardiotoxicity of isoprenaline during hypoxia.
    British journal of pharmacology, 1974, Volume: 50, Issue:3

    Topics: Animals; Bicarbonates; Blood Pressure; Carbon Dioxide; Dogs; Electrocardiography; Female; Heart; Hea

1974
Respiratory failure and isoprenaline.
    Scandinavian journal of respiratory diseases, 1974, Volume: 55, Issue:1

    Topics: Acid-Base Equilibrium; Aerosols; Airway Obstruction; Animals; Blood; Carbon Dioxide; Depression, Che

1974
A heart transplantation. 4. Anaesthesia and cardio-pulmonary bypass.
    The Medical journal of Australia, 1969, Mar-29, Volume: 1, Issue:13

    Topics: Acidosis; Anesthesia, General; Anuria; Atropine; Australia; Blood Pressure; Coronary Vessels; Extrac

1969
Effect of alterations in pulmonary blood flow on lung-exchangeable water in the dog.
    Journal of applied physiology, 1969, Volume: 27, Issue:5

    Topics: Animals; Blood Flow Velocity; Blood Pressure; Blood Volume; Cardiac Output; Chromium Isotopes; Dogs;

1969
[Description of a computer surveillance system for isolated liver: application to the study of drugs protecting the liver from anoxic lesions].
    Acta chirurgica Belgica, 1970, Volume: 69, Issue:9

    Topics: Animals; Chlorpromazine; Computers; Dogs; Extracorporeal Circulation; Hypoxia; Isoproterenol; Liver;

1970
Assessment of hypoxia in the human heart.
    Cardiology, 1972, Volume: 57, Issue:1

    Topics: Adult; Angina Pectoris; Blood Flow Velocity; Coronary Disease; Coronary Vessels; Glucose; Heart; Hum

1972
Effects of isoproterenol on heart muscle performance during myocardial hypoxia.
    Journal of molecular and cellular cardiology, 1972, Volume: 4, Issue:4

    Topics: Animals; Glucose; Glycogen; Heart; Hypoxia; Iodoacetates; Isoproterenol; Male; Methods; Muscle Contr

1972
Control of cerebral blood flow in the goat; role of the carotid rete.
    The American journal of physiology, 1972, Volume: 223, Issue:3

    Topics: Animals; Blood Flow Velocity; Blood Pressure; Brain; Carbon Dioxide; Carotid Arteries; Cerebrovascul

1972
Cardiac effects of isoproterenol, hypoxia, hypercapnia and fluorocarbon propellants and their use in asthma inhalers.
    Annals of allergy, 1972, Volume: 30, Issue:9

    Topics: Aerosols; Animals; Arrhythmias, Cardiac; Asthma; Bronchodilator Agents; Dogs; Fluorocarbon Polymers;

1972
Effect of compound aerosol of isoproterenol on physical exercise (with and without hypoxia).
    The Indian journal of chest diseases, 1971, Volume: 13, Issue:3

    Topics: Adult; Aerosols; Altitude; Humans; Hypoxia; Isoproterenol; Male; Physical Exertion

1971
Acute myocardial anoxia. Anatomical changes and their possible relation to immunological processes.
    Cardiology, 1971, Volume: 56, Issue:1

    Topics: Animals; Antibodies; Autoimmune Diseases; Humans; Hypoxia; Isoproterenol; Lymphocytes; Microscopy, E

1971
The lungs and circulation in chronic pulmonary disease.
    Journal of the Royal College of Physicians of London, 1971, Volume: 5, Issue:3

    Topics: Aminophylline; Animals; Asthma; Blood Viscosity; Carbon Dioxide; Electrocardiography; Heart Failure;

1971
Effects of 3-(3,3-diphenylpropylamino)-propyl-3',4',5'-trimethoxybenzoate (PF-26) on the experimental anoxia in rat's heart.
    Arzneimittel-Forschung, 1971, Volume: 21, Issue:11

    Topics: Amines; Animals; Benzoates; Carbohydrate Metabolism; Electrocardiography; Hypoxia; Isoproterenol; La

1971
[Hemodynamic effects of common bronchodilator agents following inhalation of aerosols].
    Zeitschrift fur Erkrankungen der Atmungsorgane mit Folia bronchologica, 1971, Volume: 135, Issue:3

    Topics: Aerosols; Asthma; Blood Pressure; Bronchitis; Cardiac Output; Heart; Heart Rate; Humans; Hypoxia; Is

1971
[Reversal of the effect of the adrenergic coronary vascular reaction in dependence upon the coronary vascular tonus].
    Pflugers Archiv fur die gesamte Physiologie des Menschen und der Tiere, 1967, Volume: 297, Issue:3

    Topics: Animals; Blood Flow Velocity; Coronary Vessels; Dipyridamole; Dogs; Epinephrine; Hypoxia; Isoprotere

1967
The pressure-flow relationship of the pulmonary circulation in normal man and in chronic obstructive pulmonary diseases. Effects of muscular exercise.
    Scandinavian journal of respiratory diseases. Supplementum, 1971, Volume: 77

    Topics: Airway Resistance; Angiography; Blood Pressure; Blood Viscosity; Blood Volume; Carbon Dioxide; Chrom

1971
Respiratory function in moderate schistosomal infection. Effect of chemotherapy.
    The American review of respiratory disease, 1969, Volume: 100, Issue:5

    Topics: Adolescent; Adult; Anthelmintics; Antimony; Blood Gas Analysis; Humans; Hypoxia; Isoproterenol; Lido

1969
[Evaluation of antianginal drugs on rabbits by electrocardiographic technique].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1969, Volume: 89, Issue:9

    Topics: Angina Pectoris; Animals; Coronary Vessels; Electrocardiography; Hypoxia; Isoproterenol; Male; Metho

1969
Metabolism of striated muscle of stress-susceptible pigs breathing oxygen or nitrogen.
    The American journal of physiology, 1970, Volume: 218, Issue:1

    Topics: Adenosine Triphosphate; Animals; Hypoxia; Isoproterenol; Lactates; Methods; Muscles; Nitrogen; Oxyge

1970
Ventilation-perfusion changes after aerosolized isoproterenol in asthma.
    The American review of respiratory disease, 1970, Volume: 101, Issue:3

    Topics: Adolescent; Adult; Aged; Asthma; Carbon Dioxide; Female; Humans; Hypoxia; Isoproterenol; Lung Compli

1970
Comparison of haemodynamic effects of intravenous isoprenaline and adrenaline after aortic valvar homograft replacement.
    British heart journal, 1970, Volume: 32, Issue:3

    Topics: Adult; Aortic Valve; Blood Pressure; Cardiac Output; Cardiac Volume; Epinephrine; Female; Heart Rate

1970
LDH isoenzyme spectrum in the myocardium of rats after repeated doses of isoproterenol.
    Experientia, 1970, May-15, Volume: 26, Issue:5

    Topics: Anemia; Animals; Heart; Heart Diseases; Hypoxia; Isoenzymes; Isoproterenol; L-Lactate Dehydrogenase;

1970
[Role of the lysosome system in the preventive effect of adaptation to high-altitude hypoxia in heart diseases].
    Kardiologiia, 1970, Volume: 10, Issue:7

    Topics: Acid Phosphatase; Adaptation, Physiological; Animals; Aortic Coarctation; Deoxyribonucleases; Diseas

1970
The cardiorespiratory effects of intravenous isoprenaline in mechanically ventilated dogs.
    British journal of anaesthesia, 1970, Volume: 42, Issue:12

    Topics: Animals; Blood Pressure; Carbon Dioxide; Cardiac Output; Dogs; Heart; Hypoxia; Injections, Intraveno

1970
[Activity of lysosome enzymes of the myocardium during adaptation to altitudinal hypoxia and heart damage].
    Doklady Akademii nauk SSSR, 1970, Volume: 195, Issue:2

    Topics: Acid Phosphatase; Adaptation, Physiological; Altitude; Animals; Aortic Coarctation; Deoxyribonucleas

1970
Effect of isoproterenol on gas exchange during air and oxygen breathing in patients with asthma.
    The American journal of medicine, 1971, Volume: 50, Issue:2

    Topics: Adult; Asthma; Bronchial Spasm; Diffusion; Humans; Hypoxia; Isoproterenol; Oxygen Inhalation Therapy

1971
Effects of haemolysed blood and adenosine diphosphate on the pulmonary vascular resistance in calves.
    Cardiovascular research, 1971, Volume: 5, Issue:3

    Topics: Adenine Nucleotides; Animals; Animals, Newborn; Aorta; Blood Pressure; Cardiac Output; Cattle; Const

1971
Effect of isoproterenol on gas exchange during air and oxygen breathing in patients with chronic pulmonary diseases.
    The American review of respiratory disease, 1971, Volume: 104, Issue:2

    Topics: Adult; Air; Asthma; Humans; Hypoxia; Isoproterenol; Lung Diseases; Middle Aged; Oxygen; Oxygen Inhal

1971
[Myocardial edema and adrenergic heart diseases].
    Zeitschrift fur Kreislaufforschung, 1967, Volume: 56, Issue:3

    Topics: Animals; Brain Injuries; Catecholamines; Endomyocardial Fibrosis; Epinephrine; Female; Heart Failure

1967
[Pharmacological and physiological studies on renal circulation. (4). Effects of changes in blood gas tension on the circulation of the perfused kidney].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1967, Nov-20, Volume: 63, Issue:6

    Topics: Acetylcholine; Animals; Blood Gas Analysis; Blood Pressure; Carbon Dioxide; Chloralose; Dogs; Electr

1967
[Hemodynamic effects of isoproterenol and propranolol in tetralogy of Fallot--development of anoxic spells and its treatment].
    Japanese circulation journal, 1967, Volume: 31, Issue:12

    Topics: Adolescent; Angiocardiography; Blood Pressure; Child; Child, Preschool; Cyanosis; Electrocardiograph

1967
Arterial hypoxaemia: a side-effect of intravenous isoprenaline used after cardiac surgery.
    Thorax, 1968, Volume: 23, Issue:1

    Topics: Adult; Blood Gas Analysis; Cardiac Output; Cardiac Surgical Procedures; Extracorporeal Circulation;

1968
Comparison of hypoxia, pH, and sympathomimetic drugs on bovine pulmonary vasculature.
    Journal of applied physiology, 1968, Volume: 24, Issue:3

    Topics: Animals; Animals, Newborn; Blood Pressure; Cattle; Epinephrine; Hydrogen-Ion Concentration; Hypoxia;

1968
Measurement of left ventricular diameter in the dog by cardiac catheterization. Validation and physiologic meaningfulness of an ultrasonic technique.
    Circulation research, 1968, Volume: 22, Issue:5

    Topics: Animals; Cardiac Catheterization; Cineradiography; Dogs; Electrocardiography; Electrophysiology; Hea

1968
[Studies on hypoxia. 3. Variations in arterial pressure, left ventricular diastolic pressure and cardiac output induced by the administration of various vasoactive drugs at different levels of acidosis].
    Bollettino della Societa italiana di biologia sperimentale, 1968, Mar-15, Volume: 44, Issue:5

    Topics: Acidosis; Animals; Blood Pressure; Cardiac Output; Dogs; Female; Heart; Hydrogen-Ion Concentration;

1968
Anthrax toxin: primary site of action.
    The Journal of infectious diseases, 1968, Volume: 118, Issue:1

    Topics: Animals; Anthrax; Blood Pressure; Brain; Electrocardiography; Heart; Heart Rate; Hypoxia; Injections

1968
[Study on anoxia. Behavior of arterial pressure, cardiac output and left ventricular diastolic pressure in anoxia caused by reduced pulmonary ventilation (modification of the above parameters by norepinephrine, isoprenaline and pitressin infusion)].
    Minerva anestesiologica, 1968, Volume: 34, Issue:3

    Topics: Acidosis, Respiratory; Animals; Blood Pressure; Cardiac Output; Dogs; Female; Hypoxia; Isoproterenol

1968
Energy metabolism in myocardium.
    Japanese circulation journal, 1968, Volume: 32, Issue:12

    Topics: Animals; Aortic Valve Stenosis; Coronary Disease; Digitalis Glycosides; Dogs; Hypoxia; Isoproterenol

1968
The cardio-toxicity of isoprenaline during hypoxia.
    British journal of pharmacology, 1969, Volume: 36, Issue:1

    Topics: Animals; Blood Pressure; Dogs; Heart; Heart Arrest; Heart Rate; Hypoxia; Isoproterenol; Propranolol

1969
Effect of hypoxia on the vascular response to isoproterenol and norepinephrine.
    American heart journal, 1969, Volume: 77, Issue:4

    Topics: Animals; Blood Pressure; Dogs; Femoral Artery; Femoral Vein; Hypoxia; Isoproterenol; Norepinephrine;

1969
Influence of alcohol on coronary function in rabbits with atherosclerosis induced by cholesterol.
    Nature, 1969, Mar-15, Volume: 221, Issue:5185

    Topics: Animals; Arteriosclerosis; Cholesterol; Coronary Disease; Coronary Vessels; Epinephrine; Ethanol; Ex

1969
Influences of coronary blood flow and hypoxia upon the cardiac responses to isoproterenol.
    The Annals of thoracic surgery, 1969, Volume: 7, Issue:6

    Topics: Animals; Blood Flow Velocity; Cardiac Output; Coronary Disease; Coronary Vessels; Dogs; Heart; Heart

1969
Isoprenaline and intrapulmonary shunting.
    British journal of anaesthesia, 1969, Volume: 41, Issue:6

    Topics: Animals; Carbon Dioxide; Dogs; Hypoxia; Isoproterenol; Oxygen; Pulmonary Circulation; Ventilation-Pe

1969
Role of beta-adrenergic receptors in the circulatory response to hypoxia.
    The American journal of physiology, 1969, Volume: 217, Issue:3

    Topics: Adrenal Glands; Adrenalectomy; Animals; Catecholamines; Dogs; Electric Stimulation; Heart Conduction

1969
Management of cardiac and respiratory arrest in children. A survey of major principles of therapy.
    Clinical pediatrics, 1969, Volume: 8, Issue:11

    Topics: Acidosis; Arrhythmias, Cardiac; Bicarbonates; Child; Child, Preschool; Electrocardiography; Epinephr

1969
Hemodynamic study of myocardial heat transfer.
    Journal of applied physiology, 1965, Volume: 20, Issue:4

    Topics: Anemia; Animals; Blood Pressure; Body Temperature; Body Temperature Regulation; Cardiac Output; Coro

1965
Increased resistance of the myocardium to anoxia in vitro after repeated application of isoprenalin.
    Physiologia bohemoslovenica, 1965, Volume: 14, Issue:6

    Topics: Animals; Heart; Heart Ventricles; Hypoxia; In Vitro Techniques; Isoproterenol; Male; Myocardium; Org

1965
Coronary circulation of the avian heart.
    Archives internationales de pharmacodynamie et de therapie, 1965, Volume: 157, Issue:2

    Topics: Acetylcholine; Adaptation, Physiological; Animals; Birds; Blood Circulation; Coronary Vessels; Diben

1965
Experimental observations on the improbability of totally implantable pacemaker-induced ventricular fibrillation. Preliminary report.
    Transactions - American Society for Artificial Internal Organs, 1964, Volume: 10

    Topics: Animals; Dogs; Hypoxia; Isoproterenol; Ouabain; Pacemaker, Artificial; Ventricular Fibrillation

1964
Flowmeter studies of internal mammary artery function after implantation into the left ventricular myocardium.
    The Journal of thoracic and cardiovascular surgery, 1966, Volume: 52, Issue:6

    Topics: Amyl Nitrite; Animals; Blood Flow Velocity; Blood Gas Analysis; Coronary Disease; Coronary Vessels;

1966