isoproterenol has been researched along with Hypokalemia in 43 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Hypokalemia: Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to test the hypothesis that late phase 3 early afterdepolarization (EAD) induced by IKATP activation underlies the mechanisms of ES during isoproterenol infusion and hypokalemia." | 7.80 | Hypokalemia promotes late phase 3 early afterdepolarization and recurrent ventricular fibrillation during isoproterenol infusion in Langendorff perfused rabbit ventricles. ( Ai, T; Chang, PC; Chen, PS; Chua, SK; Lee, YS; Lin, SF; Maruyama, M; Park, HW; Shen, MJ, 2014) |
| "The relationship between antibronchospasmic, tachycardiac, or hypokalaemic effects and plasma concentration of L-isoproterenol (ISP) hydrochloride was investigated in guinea-pigs in vivo." | 7.69 | Antibronchospasmic, tachycardiac, and hypokalaemic effects of L-isoproterenol in guinea-pigs. ( Iga, T; Ohtani, H; Sawada, Y; Yamamoto, K, 1995) |
| "Hypokalemia potentiated the arryhthmogenic effects of digoxin and promoted inhibition of cardiac Na+,K+-ATPase." | 7.66 | Effects of hypokalemia on the cardiotropic actions of digoxin in dogs. Correlation with inhibition of cardiac Na+,K+-adenosine triphosphatase. ( Gelbart, A; Goldman, R; Hall, RJ, 1980) |
| "An in vivo study of skeletal muscle paralysis induced by intravenous barium chloride has been made in curarized and non-curarized rats." | 7.65 | Barium-induced skeletal muscle paralysis in the rat, and its relationship to human familial periodic paralysis. ( McArdle, B; Schott, GD, 1974) |
| "Cetamolol was able to block epinephrine-induced hypokalemia completely, in a dose-related manner, and to block isoproterenol-induced hypokalemia partially." | 5.28 | Comparison of the effects of cetamolol and atenolol on epinephrine- and isoproterenol-induced hypokalemia in anesthetized dogs. ( Klein, M; Nettler, S; Oshiro, G; Smith, T; Stupienski, RF, 1989) |
| " We describe a severe case of refractory TdP in the setting of methadone, cocaine, hypokalemia and hypomagnesemia." | 3.91 | Severe Torsades de Pointes with acquired QT prolongation. ( Narang, A; Ozcan, C, 2019) |
| "The purpose of this study was to test the hypothesis that late phase 3 early afterdepolarization (EAD) induced by IKATP activation underlies the mechanisms of ES during isoproterenol infusion and hypokalemia." | 3.80 | Hypokalemia promotes late phase 3 early afterdepolarization and recurrent ventricular fibrillation during isoproterenol infusion in Langendorff perfused rabbit ventricles. ( Ai, T; Chang, PC; Chen, PS; Chua, SK; Lee, YS; Lin, SF; Maruyama, M; Park, HW; Shen, MJ, 2014) |
| "The relationship between antibronchospasmic, tachycardiac, or hypokalaemic effects and plasma concentration of L-isoproterenol (ISP) hydrochloride was investigated in guinea-pigs in vivo." | 3.69 | Antibronchospasmic, tachycardiac, and hypokalaemic effects of L-isoproterenol in guinea-pigs. ( Iga, T; Ohtani, H; Sawada, Y; Yamamoto, K, 1995) |
| "Hypokalemia potentiated the arryhthmogenic effects of digoxin and promoted inhibition of cardiac Na+,K+-ATPase." | 3.66 | Effects of hypokalemia on the cardiotropic actions of digoxin in dogs. Correlation with inhibition of cardiac Na+,K+-adenosine triphosphatase. ( Gelbart, A; Goldman, R; Hall, RJ, 1980) |
| "Isoproterenol and propranolol, in a single dose, caused hyperglycemia after 15 and 30 min, either in the conscious rat or in the anesthetized dog." | 3.65 | Metabolic responses to catecholamines. ( Aramendía, P; Márquez, MT; Puntoni de Mikulic, LE, 1976) |
| "An in vivo study of skeletal muscle paralysis induced by intravenous barium chloride has been made in curarized and non-curarized rats." | 3.65 | Barium-induced skeletal muscle paralysis in the rat, and its relationship to human familial periodic paralysis. ( McArdle, B; Schott, GD, 1974) |
| "Cetamolol was able to block epinephrine-induced hypokalemia completely, in a dose-related manner, and to block isoproterenol-induced hypokalemia partially." | 1.28 | Comparison of the effects of cetamolol and atenolol on epinephrine- and isoproterenol-induced hypokalemia in anesthetized dogs. ( Klein, M; Nettler, S; Oshiro, G; Smith, T; Stupienski, RF, 1989) |
| "Patients with hypokalemia due to Bartter's syndrome show an increase in adrenergic nervous system function with significantly elevated plasma norepinephrine excretion." | 1.27 | Defective leukocyte adenylate cyclase function in hypokalemia. ( Güllner, HG, 1984) |
| "This hypokalemia is not mediated by insulin, renin or aldosterone." | 1.27 | Hypokalemia from beta 2-receptor stimulation by circulating epinephrine. ( Brown, MJ, 1985) |
| "LV digoxin was also similar in control and depleted dogs." | 1.26 | Effect of chronic potassium depletion on digitalis-induced inotropy and arrhythmias. ( Billingham, M; Gelbart, A; Goldman, RH; Hall, RJ; Snidow, G, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (72.09) | 18.7374 |
| 1990's | 6 (13.95) | 18.2507 |
| 2000's | 3 (6.98) | 29.6817 |
| 2010's | 3 (6.98) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maruyama, M | 1 |
| Ai, T | 1 |
| Chua, SK | 1 |
| Park, HW | 1 |
| Lee, YS | 1 |
| Shen, MJ | 1 |
| Chang, PC | 1 |
| Lin, SF | 1 |
| Chen, PS | 1 |
| Narang, A | 1 |
| Ozcan, C | 1 |
| Nissen, JD | 1 |
| Thomsen, MB | 1 |
| Bentzen, BH | 1 |
| Diness, JG | 1 |
| Diness, TG | 1 |
| Jespersen, T | 1 |
| Grunnet, M | 1 |
| Geukes Foppen, RJ | 1 |
| Siegenbeek Van Heukelom, J | 1 |
| PRIORESCHI, P | 1 |
| ROSENMANN, E | 1 |
| GAZENFIELD, E | 1 |
| LAUFER, A | 1 |
| DAVIES, AM | 1 |
| RONA, G | 1 |
| KAHN, DS | 1 |
| CHAPPEL, CI | 1 |
| GOODYER, AV | 1 |
| GOODKIND, MJ | 1 |
| STANLEY, EJ | 1 |
| Kovács, A | 1 |
| Szénási, G | 1 |
| Piao, L | 1 |
| Li, J | 1 |
| McLerie, M | 1 |
| Lopatin, AN | 1 |
| Güllner, HG | 1 |
| Hall, RJ | 2 |
| Gelbart, A | 2 |
| Billingham, M | 1 |
| Snidow, G | 1 |
| Goldman, RH | 1 |
| Brown, MJ | 2 |
| Brown, DC | 1 |
| Murphy, MB | 1 |
| Goldman, R | 1 |
| Timár, S | 1 |
| Bruncsák, A | 1 |
| Pack, RJ | 1 |
| Alley, MR | 1 |
| Dallimore, JA | 1 |
| Lapwood, KR | 1 |
| Burgess, C | 1 |
| Crane, J | 1 |
| Mei, KZ | 1 |
| Sun, AH | 1 |
| Li, BJ | 1 |
| Ohtani, H | 1 |
| Yamamoto, K | 1 |
| Sawada, Y | 1 |
| Iga, T | 1 |
| Jauchem, JR | 1 |
| Vick, RL | 1 |
| Jerusalem, F | 1 |
| Barrillon, A | 1 |
| Grand, A | 1 |
| Klauser, H | 1 |
| Klauser-Reucker, C | 1 |
| Moccetti, T | 1 |
| Puntoni de Mikulic, LE | 1 |
| Márquez, MT | 1 |
| Aramendía, P | 1 |
| Ebihara, Y | 1 |
| Nakamura, Y | 1 |
| Vera, Z | 1 |
| Janzen, D | 1 |
| Desai, J | 1 |
| Lipworth, BJ | 1 |
| Tregaskis, BF | 1 |
| McDevitt, DG | 1 |
| Klein, M | 1 |
| Stupienski, RF | 1 |
| Nettler, S | 1 |
| Smith, T | 1 |
| Oshiro, G | 1 |
| Elsner, D | 1 |
| Kromer, EP | 1 |
| Riegger, AJ | 1 |
| Winslow, E | 1 |
| Walker, G | 1 |
| Mason, R | 1 |
| Larsson, K | 1 |
| Hjemdahl, P | 1 |
| Salerno, DM | 1 |
| Murakami, M | 1 |
| Elsperger, KJ | 1 |
| Vincent, HH | 1 |
| Man in't Veld, AJ | 1 |
| Boomsma, F | 1 |
| Schalekamp, MA | 1 |
| González, R | 1 |
| Mercadal, E | 1 |
| Alburquerque, J | 1 |
| Martínez, A | 1 |
| Raynaud, R | 1 |
| Brochier, M | 1 |
| Néel, JL | 1 |
| Fauchier, JP | 1 |
| Raynaud, P | 1 |
| Bens, JL | 1 |
| Duboisset, M | 1 |
| Quiret, JC | 1 |
| Lesbre, JP | 1 |
| Bernasconi, P | 1 |
| Grossman, JI | 1 |
| Rubin, IL | 1 |
| Coumel, P | 1 |
| Schott, GD | 1 |
| McArdle, B | 1 |
| Yoshitake, T | 1 |
| Mizuno, A | 1 |
| Saigusa, M | 1 |
| Kato, T | 1 |
| Patton, RD | 1 |
| Hoffman, SA | 1 |
| Wallace, HW | 1 |
| Baue, AE | 1 |
| Blakemore, WS | 1 |
| Zinsser, HF | 1 |
| Pocidalo, JJ | 1 |
| Gaudebout, C | 1 |
| Vallois, J | 1 |
| Sibille, L | 1 |
| Blayo, MC | 1 |
5 reviews available for isoproterenol and Hypokalemia
| Article | Year |
|---|---|
EXPERIMENTAL CARDIAC NECROSIS.
Topics: Chlorides; Desoxycorticosterone; Dihydrotachysterol; Heart; Humans; Hypokalemia; Isoproterenol; Magn | 1963 |
STUDIES ON INFARCT-LIKE MYOCARDIAL NECROSIS PRODUCED BY ISOPROTERENOL: A REVIEW.
Topics: Desoxycorticosterone; Dogs; Epinephrine; Heart Diseases; Hyperthyroidism; Hypokalemia; Isoproterenol | 1963 |
[Treatment of myopathies and spinal muscular atrophies (author's transl)].
Topics: Amyotrophic Lateral Sclerosis; Azathioprine; Collagen Diseases; Dermatomyositis; Glycogen Storage Di | 1978 |
[Incompatibility and interference of the major cardiologic drugs. Their undesirable effects].
Topics: Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Antihypertensive Agents; Bradycardia; Cardiac Glyc | 1976 |
Management of arrhythmias in acute myocardial infarction.
Topics: Acid-Base Equilibrium; Adams-Stokes Syndrome; Arrhythmias, Cardiac; Atropine; Bradycardia; Cardiac O | 1971 |
3 trials available for isoproterenol and Hypokalemia
| Article | Year |
|---|---|
Hypokalemia from beta2-receptor stimulation by circulating epinephrine.
Topics: Adult; Epinephrine; Heart Rate; Humans; Hypokalemia; Insulin; Isoproterenol; Male; Norepinephrine; P | 1983 |
Comparison of hypokalaemic, electrocardiographic and haemodynamic responses to inhaled isoprenaline and salbutamol in young and elderly subjects.
Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Aging; Albuterol; Dose-Response Relation | 1991 |
[Syncope by volley of ventricular spikes induced or encouraged by prenylamine].
Topics: Aged; Benzofurans; Bradycardia; Clinical Trials as Topic; Drug Combinations; Electrocardiography; Fe | 1973 |
35 other studies available for isoproterenol and Hypokalemia
| Article | Year |
|---|---|
Hypokalemia promotes late phase 3 early afterdepolarization and recurrent ventricular fibrillation during isoproterenol infusion in Langendorff perfused rabbit ventricles.
Topics: Animals; Calcium; Heart Ventricles; Hypokalemia; In Vitro Techniques; Infusions, Intravenous; Isopro | 2014 |
Severe Torsades de Pointes with acquired QT prolongation.
Topics: Administration, Intravenous; Anti-Arrhythmia Agents; Benzodiazepines; Chest Pain; Cocaine; Echocardi | 2019 |
Attenuated ventricular β-adrenergic response and reduced repolarization reserve in a rabbit model of chronic heart failure.
Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Cardiac Pacing, Artificial; Chronic Disease; D | 2012 |
Isoprenaline-stimulated differential adrenergic response of K+ channels in skeletal muscle under hypokalaemic conditions.
Topics: Adrenergic beta-2 Receptor Agonists; Animals; Female; Hypokalemia; Isoproterenol; Membrane Potential | 2003 |
ISOPROTERENOL INDUCED MYOCARDIAL LESIONS IN THE IMMUNIZED AND NON-IMMUNIZED RAT. 1. HISTOPATHOLOGICAL LESIONS IN NORMAL RATS.
Topics: Antibodies; Heart; Hypokalemia; Immunization; Isoproterenol; Necrosis; Pathology; Pharmacology; Pota | 1964 |
THE EFFECTS OF ABNORMAL CONCENTRATIONS OF THE SERUM ELECTROLYTES ON LEFT VENTRICULAR FUNCTION IN THE INTACT ANIMAL.
Topics: Acidosis; Alkalosis; Animals; Blood Pressure; Dogs; Edetic Acid; Electrolytes; Heart; Heart Arrest; | 1964 |
Effects of dofetilide and EGIS-7229, an antiarrhythmic agent possessing class III, IV, and IB activities, on myocardial refractoriness in hyperkalemia, hypokalemia, and during beta-adrenergic activation in the rabbit papillary muscle in vitro.
Topics: Adrenergic beta-Agonists; Animals; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Electri | 2006 |
Transgenic upregulation of IK1 in the mouse heart is proarrhythmic.
Topics: Action Potentials; Anesthetics, Inhalation; Animals; Arrhythmias, Cardiac; Cardiotonic Agents; Cathe | 2007 |
Defective leukocyte adenylate cyclase function in hypokalemia.
Topics: Adenylyl Cyclases; Alprostadil; Bartter Syndrome; Cyclic AMP; Female; Humans; Hyperaldosteronism; Hy | 1984 |
Effect of chronic potassium depletion on digitalis-induced inotropy and arrhythmias.
Topics: Animals; Arrhythmias, Cardiac; Binding Sites; Digoxin; Dogs; Female; Heart Conduction System; Heart | 1981 |
Effects of hypokalemia on the cardiotropic actions of digoxin in dogs. Correlation with inhibition of cardiac Na+,K+-adenosine triphosphatase.
Topics: Acute Disease; Adenosine Triphosphatases; Animals; Chronic Disease; Digoxin; Dogs; Hypokalemia; Isop | 1980 |
[Chaotic ventricular tachycardia].
Topics: Aged; Bradycardia; Electrocardiography; Female; Humans; Hypokalemia; Isoproterenol; Middle Aged; Pac | 1980 |
The myocardial effects of fenoterol, isoprenaline and salbutamol in normoxic and hypoxic sheep.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Female; Fenoterol; Heart; Heart Rate; Hypokalemia; Hyp | 1994 |
[Classification and treatment of torsades de pointes (TdP): a report of 11 cases].
Topics: Aged; Female; Heart Block; Humans; Hypokalemia; Isoproterenol; Long QT Syndrome; Magnesium Sulfate; | 1993 |
Antibronchospasmic, tachycardiac, and hypokalaemic effects of L-isoproterenol in guinea-pigs.
Topics: Adrenergic beta-Agonists; Analysis of Variance; Animals; Bronchial Spasm; Bronchoconstrictor Agents; | 1995 |
Isoproterenol-induced hypokalemia: role of the liver.
Topics: Animals; Dogs; Female; Hypokalemia; Isoproterenol; Liver; Male; Potassium; Receptors, Adrenergic, be | 1979 |
[Ventricular tachycardia "with reversal of points" and electrolyte disorders].
Topics: Aged; Electrocardiography; Female; Humans; Hypokalemia; Isoproterenol; Magnesium; Male; Middle Aged; | 1977 |
Metabolic responses to catecholamines.
Topics: Animals; Catecholamines; Dogs; Drug Interactions; Epinephrine; Hyperglycemia; Hyperkalemia; Hypokale | 1976 |
[Torsade de pointes].
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Electrocardiography | 1991 |
Acute hypokalemia and inducibility of ventricular tachyarrhythmia in a nonischemic canine model.
Topics: Acute Disease; Animals; Dogs; Female; Furosemide; Hypokalemia; Insulin; Isoproterenol; Male; Membran | 1991 |
Comparison of the effects of cetamolol and atenolol on epinephrine- and isoproterenol-induced hypokalemia in anesthetized dogs.
Topics: Acetamides; Adrenergic beta-Antagonists; Anesthesia; Animals; Atenolol; Dogs; Dose-Response Relation | 1989 |
Effects of selective and nonselective beta-adrenoceptor antagonism on isoproterenol-stimulated myocardial potassium uptake in the intact dog.
Topics: Animals; Dogs; Female; Hemodynamics; Hypokalemia; Isoproterenol; Male; Metoprolol; Myocardium; Potas | 1989 |
Antiarrhythmic effects of selective beta 1- and beta 2- and nonselective beta-adrenoceptor blockade in normokalaemic and dietary-induced hypokalaemic rats.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; | 1989 |
Cardiovascular and hypokalaemic effects of inhaled salbutamol, fenoterol, and isoprenaline.
Topics: Albuterol; Bronchodilator Agents; Fenoterol; Hemodynamics; Humans; Hypokalemia; Isoproterenol | 1989 |
Effects of pretreatment with propranolol on potassium, calcium, and magnesium shifts after ventricular fibrillation in dogs.
Topics: Animals; Blood Glucose; Calcium; Dogs; Dopamine; Epinephrine; Hemodynamics; Hypokalemia; Isoproteren | 1989 |
Prevention of epinephrine-induced hypokalemia by nonselective beta blockers.
Topics: Adrenergic beta-Antagonists; Albuterol; Dose-Response Relationship, Drug; Epinephrine; Humans; Hypok | 1985 |
Hypokalemia from beta 2-receptor stimulation by circulating epinephrine.
Topics: Adrenergic beta-Antagonists; Digoxin; Dose-Response Relationship, Drug; Epinephrine; Heart Rate; Hum | 1985 |
[Torsade de pointes: clinical experience of 9 patients].
Topics: Adult; Aged; Amiodarone; Coronary Disease; Electrocardiography; Female; Humans; Hypokalemia; Isoprot | 1988 |
[Ventricular tachycardia with variable focus and dyskaliemia].
Topics: Aged; Alcoholism; Bradycardia; Cardiac Complexes, Premature; Electrocardiography; Female; Heart Bloc | 1969 |
Cardiopulmonary resuscitation. II.
Topics: Acidosis; Aftercare; Bradycardia; Heart Arrest; Humans; Hyperkalemia; Hypokalemia; Isoproterenol; Li | 1969 |
[Hypokalemia and disorders of cardiac rhythm].
Topics: Arrhythmias, Cardiac; Electric Countershock; Heart Massage; Humans; Hypokalemia; Isoproterenol; Pota | 1973 |
Barium-induced skeletal muscle paralysis in the rat, and its relationship to human familial periodic paralysis.
Topics: Adrenal Glands; Animals; Arrhythmias, Cardiac; Barium; Calcium; Female; Hypertension; Hypokalemia; I | 1974 |
Relationship of plasma aldosterone concentration to electrolytes and acid-base balance in blood after open cardiac surgery.
Topics: Acid-Base Equilibrium; Adult; Aldosterone; Aortic Valve; Blood; Carbon Dioxide; Cardiac Output; Coro | 1974 |
Postoperative ventricular arrhythmias caused by isoproterenol. Conversion with insulin.
Topics: Animals; Digitalis; Dogs; Hyperkalemia; Hypokalemia; Insulin; Isoproterenol; Membrane Potentials; Pl | 1969 |
[Metabolic acidosis with hypokalemia during isoproterenol perfusion in dogs].
Topics: Acidosis; Animals; Dogs; Hydrogen-Ion Concentration; Hypokalemia; Isoproterenol; Lactates; Perfusion | 1970 |