isoproterenol has been researched along with Hypoglycemia in 34 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Hypoglycemia: A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Insulin-induced hypoglycemia (IIH) promoted decreased responsiveness of hepatic glycogen catabolism to phenylephrine and isoproterenol, but not to glucagon and cyanide." | 7.70 | Responsiveness of glycogen catabolism to adrenergic agonists during insulin-induced hypoglycemia in rat livers. ( Bazotte, RB; Hell, NS; Lima, FB; Lopes, G; Vardanega, M, 1998) |
| "beta-Adrenergic sensitivity was measured by isoproterenol testing before and at 2 and 4 months after strict avoidance of hypoglycemia." | 5.09 | Avoidance of hypoglycemia restores hypoglycemia awareness by increasing beta-adrenergic sensitivity in type 1 diabetes. ( Fritsche, A; Gerich, J; Häring, H; Stefan, N; Stumvoll, M, 2001) |
| "The activities of glycogen phosphorylase and synthase during infusions of glucagon, isoproterenol, or cyanide in isolated liver of fed rats submitted to short-term insulin-induced hypoglycemia (IIH) was investigated." | 3.74 | Liver glycogen metabolism during short-term insulin-induced hypoglycemia in fed rats. ( Bazotte, RB; Curi, R; Lopes-Bertolini, G; Obici, S, 2008) |
| " Insulin-induced hypoglycemia (IIH) promoted decreased responsiveness of hepatic glycogen catabolism to phenylephrine and isoproterenol, but not to glucagon and cyanide." | 3.70 | Responsiveness of glycogen catabolism to adrenergic agonists during insulin-induced hypoglycemia in rat livers. ( Bazotte, RB; Hell, NS; Lima, FB; Lopes, G; Vardanega, M, 1998) |
| "The synergistic effect of combined injection of glucagon (G), cortisol (C) and phenylephrine+isoproterenol (E) during hypoglycemia in male adult Wistar rats was investigated." | 3.69 | Effect of combined administration of counterregulatory hormones during insulin-induced hypoglycemia in rats: lipolysis mediated by a beta-adrenergic mechanism contributes to hyperglycemia. ( Bazotte, RB; Hell, NS; Lopes, G; Souza, HM, 1994) |
| " The dose-response curve of isoprenaline/HR was significantly shifted to the right after hypoglycemia." | 2.68 | Reduced beta-adrenergic sensitivity in healthy volunteers induced by hypoglycemia. ( Jaeger, R; Jorde, R; Sager, G; Trovik, TS, 1995) |
| "Metoprolol was given together with the dose of isoprenaline which increased heart rate by 25 beats min-1." | 2.67 | Reduced sensitivity to beta-adrenoceptor stimulation and blockade in insulin dependent diabetic patients with hypoglycaemia unawareness. ( Jaeger, R; Jorde, R; Sager, G; Trovik, TS, 1994) |
| "Hypoglycemia was induced with insulin and its effects on cerebral blood flow (measured with an electromagnetic flow transducer placed on the internal maxillary artery) were studied in awake goats under control conditions and after administration of the nitric oxide synthesis inhibitor N(G)-nitro-L-arginine methyl ester (L-NAME, 47 mg/kg)." | 1.30 | Role of nitric oxide in the effects of hypoglycemia on the cerebral circulation in awake goats. ( Diéguez, G; Fernández, N; García, JL; García-Villalón, AL; Gomez, B; Monge, L, 1997) |
| "A total of 21 subjects with type 1 diabetes underwent a standardized insulin infusion protocol to produce a stepwise decrease in plasma glucose to 45-min plateaus of 4." | 1.30 | Reduced beta-adrenergic sensitivity in patients with type 1 diabetes and hypoglycemia unawareness. ( Cryer, PE; Gerich, JE; Korytkowski, MT; Mitrakou, A; Mokan, M; Veneman, TF, 1998) |
| "(a) Acute hyperglycemia is obtained from a condition of IIH by combined i." | 1.29 | Synergistic effect of counterregulatory hormones during insulin-induced hypoglycemia in rats: participation of lipolysis and gluconeogenesis to hyperglycemia. ( Bazotte, RB; Hell, NS; Lopes, G; Souza, HM, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (41.18) | 18.7374 |
| 1990's | 16 (47.06) | 18.2507 |
| 2000's | 4 (11.76) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Obici, S | 1 |
| Lopes-Bertolini, G | 1 |
| Curi, R | 2 |
| Bazotte, RB | 5 |
| Walter, RM | 1 |
| Dudl, RJ | 1 |
| Palmer, JP | 1 |
| Ensinck, JW | 1 |
| Phaosawasdi, K | 1 |
| Goppold, R | 1 |
| Fisher, RS | 1 |
| Artman, M | 1 |
| Graham, TP | 1 |
| Souza, HM | 2 |
| Hell, NS | 3 |
| Lopes, G | 4 |
| Trovik, TS | 5 |
| Jaeger, R | 2 |
| Jorde, R | 4 |
| Sager, G | 5 |
| Berlin, I | 1 |
| Grimaldi, A | 1 |
| Landault, C | 1 |
| Cesselin, F | 1 |
| Puech, AJ | 1 |
| Schwab, KO | 1 |
| Bartels, H | 1 |
| Martin, C | 1 |
| Leichtenschlag, EM | 1 |
| Vaartun, A | 2 |
| Diéguez, G | 1 |
| Fernández, N | 1 |
| García, JL | 1 |
| García-Villalón, AL | 1 |
| Monge, L | 1 |
| Gomez, B | 1 |
| Vea, H | 1 |
| Birkeland, K | 1 |
| Revhaug, A | 1 |
| Sundsfjord, J | 1 |
| Lima, FB | 2 |
| Vardanega, M | 1 |
| Fritsche, A | 3 |
| Stumvoll, M | 3 |
| Grüb, M | 1 |
| Sieslack, S | 1 |
| Renn, W | 1 |
| Schmülling, RM | 1 |
| Häring, HU | 2 |
| Gerich, JE | 3 |
| Korytkowski, MT | 1 |
| Mokan, M | 1 |
| Veneman, TF | 1 |
| Mitrakou, A | 1 |
| Cryer, PE | 1 |
| Vardanega-Peicher, M | 1 |
| Nakano, LC | 1 |
| Stefan, N | 1 |
| Häring, H | 1 |
| Gerich, J | 1 |
| Katada, T | 1 |
| Ui, M | 1 |
| Chideckel, EW | 1 |
| Palmer, J | 1 |
| Koerker, DJ | 1 |
| Ensinck, J | 1 |
| Davidson, MB | 1 |
| Goodner, CJ | 1 |
| Negri, F | 1 |
| Fratelli, M | 1 |
| Fratino, P | 1 |
| Melzi d'Eril, G | 1 |
| Finardi, G | 1 |
| De Blasi, A | 1 |
| van Tits, LJ | 1 |
| Daul, A | 1 |
| Bauch, HJ | 1 |
| Grosse-Wilde, H | 1 |
| Happel, M | 1 |
| Michel, MC | 1 |
| Brodde, OE | 1 |
| Wolf, JP | 1 |
| Massol, J | 1 |
| Nguyen, NU | 1 |
| Berthelay, S | 1 |
| Kahn, CR | 1 |
| Neville, DM | 1 |
| Roth, J | 1 |
| Sato, T | 1 |
| Gulbenkian, A | 1 |
| Schobert, L | 1 |
| Tabachnick, II | 1 |
| Loubatières, A | 1 |
| Mariani, MM | 1 |
| Savi, L | 1 |
| Sorel, G | 1 |
| Warndorff, JA | 1 |
| Wolpowitz, A | 1 |
| Voss, TJ | 1 |
| Barnard, CN | 1 |
| Barnard, MS | 1 |
| Lundquist, I | 1 |
| Ekholm, R | 1 |
| Ericson, LE | 1 |
| Mennear, JH | 1 |
| Spratto, GR | 1 |
| Miya, TS | 1 |
| Abramson, EA | 1 |
| Arky, RA | 1 |
1 review available for isoproterenol and Hypoglycemia
| Article | Year |
|---|---|
Congestive heart failure in infancy: recognition and management.
Topics: Acute Kidney Injury; Airway Obstruction; Anemia, Hemolytic; Arteriovenous Fistula; Asphyxia Neonator | 1982 |
4 trials available for isoproterenol and Hypoglycemia
| Article | Year |
|---|---|
Reduced beta-adrenergic sensitivity in healthy volunteers induced by hypoglycemia.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Humans; Hypoglyce | 1995 |
Reduced sensitivity to beta-adrenoceptor stimulation and blockade in insulin dependent diabetic patients with hypoglycaemia unawareness.
Topics: Adult; Analysis of Variance; Awareness; Blood Glucose; Blood Pressure; Chromatography, High Pressure | 1994 |
Suspected postprandial hypoglycemia is associated with beta-adrenergic hypersensitivity and emotional distress.
Topics: Adult; Blood Glucose; Blood Pressure; C-Peptide; Catecholamines; Eating; Female; Glucose; Glucose To | 1994 |
Avoidance of hypoglycemia restores hypoglycemia awareness by increasing beta-adrenergic sensitivity in type 1 diabetes.
Topics: Adult; Analysis of Variance; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Glucose Clamp Te | 2001 |
29 other studies available for isoproterenol and Hypoglycemia
| Article | Year |
|---|---|
Liver glycogen metabolism during short-term insulin-induced hypoglycemia in fed rats.
Topics: Animals; Enzyme Activation; Feeding Behavior; Glucagon; Glucose; Glycogen Phosphorylase; Glycogen Sy | 2008 |
The failure of aminophylline to modulate glucagon release in man.
Topics: Adolescent; Adult; Aminophylline; Arginine; Cyclic AMP; Glucagon; Humans; Hypoglycemia; Insulin; Ins | 1982 |
Pyloric pressure response to insulin-induced hypoglycemia in humans.
Topics: Atropine; Blood Glucose; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epinephrine; G | 1981 |
Effect of combined administration of counterregulatory hormones during insulin-induced hypoglycemia in rats: lipolysis mediated by a beta-adrenergic mechanism contributes to hyperglycemia.
Topics: Animals; Drug Synergism; Drug Therapy, Combination; Gastrointestinal Agents; Glucagon; Hydrocortison | 1994 |
Decreased beta 2-adrenoceptor density and decreased isoproterenol induced c-AMP increase in juvenile type I diabetes mellitus: an additional cause of severe hypoglycaemia in childhood diabetes?
Topics: Adolescent; Adult; Child; Child, Preschool; Cyclic AMP; Diabetes Mellitus, Type 1; Granulocytes; Hum | 1993 |
Altered cAMP response after isoprenaline stimulation of mononuclear leucocytes from insulin-dependent diabetic patients with hypoglycaemia unawareness.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Analysis of Variance; Binding, Competitive; C | 1995 |
Dysfunction in the beta 2-adrenergic signal pathway in patients with insulin dependent diabetes mellitus (IDDM) and unawareness of hypoglycaemia.
Topics: Adrenergic beta-Agonists; Adult; Binding, Competitive; Diabetes Mellitus, Type 1; Female; Humans; Hy | 1995 |
Role of nitric oxide in the effects of hypoglycemia on the cerebral circulation in awake goats.
Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Cerebrovascular Circulation; Diazoxide; Drug Inter | 1997 |
Return of beta-adrenergic sensitivity in a patient with insulinoma after removal of the tumour.
Topics: Adrenergic beta-Agonists; Adult; Blood Glucose; Epinephrine; Glucagon; Human Growth Hormone; Humans; | 1997 |
Responsiveness of glycogen catabolism to adrenergic agonists during insulin-induced hypoglycemia in rat livers.
Topics: Adrenergic Agonists; Animals; Area Under Curve; Cyanides; Gastrointestinal Agents; Glucagon; Glucose | 1998 |
Effect of hypoglycemia on beta-adrenergic sensitivity in normal and type 1 diabetic subjects.
Topics: Adrenergic beta-Agonists; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Gluc | 1998 |
Reduced beta-adrenergic sensitivity in patients with type 1 diabetes and hypoglycemia unawareness.
Topics: Adrenergic beta-Agonists; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Female; Hear | 1998 |
Synergistic effect of counterregulatory hormones during insulin-induced hypoglycemia in rats: participation of lipolysis and gluconeogenesis to hyperglycemia.
Topics: Animals; Blood Glucose; Drug Synergism; Fasting; Fatty Acids, Nonesterified; Glucagon; Gluconeogenes | 1996 |
Reversal of hypoglycemia unawareness in a long-term type 1 diabetic patient by improvement of beta-adrenergic sensitivity after prevention of hypoglycemia.
Topics: Adrenergic beta-Agonists; Adult; Awareness; Blood Glucose; Chronic Disease; Diabetes Mellitus, Type | 2000 |
Time sequence of changes in the responsiveness of glycogen breakdown to adrenergic agonists in perfused liver of rats with insulin-induced hypoglycemia.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Bucladesine; Glucose; Glycolysis; Hypo | 2000 |
Accelerated turnover of blood glucose in pertussis-sensitized rats due to combined actions of endogenous insulin and adrenergic beta-stimulation.
Topics: Animals; Bicarbonates; Blood Glucose; Diabetes Mellitus; Epinephrine; Heart; Hypoglycemia; Insulin; | 1976 |
Somatostatin blockade of acute and chronic stimuli of the endocrine pancreas and the consequences of this blockade on glucose homeostasis.
Topics: Animals; Blood Glucose; Depression, Chemical; Female; Glucagon; Glucose; Haplorhini; Homeostasis; Hy | 1975 |
High plasma levels of catecholamines during insulin-induced hypoglycemic stress do not cause beta-adrenergic receptor sequestration.
Topics: Adrenal Medulla; Adult; Catecholamines; Colforsin; Cyclic AMP; Epinephrine; Female; Humans; Hypoglyc | 1992 |
Effects of insulin-induced hypoglycemia on beta 2-adrenoceptor density and proliferative responses of human lymphocytes.
Topics: Adult; Blood Glucose; Blood Pressure; Cell Division; Cyclic AMP; Epinephrine; Female; Humans; Hypogl | 1990 |
Arginine vasopressin response to insulin-induced hypoglycemia in insulin-dependent diabetics with asymptomatic hypoglycemia.
Topics: Adult; Arginine Vasopressin; Diabetes Mellitus, Type 1; Epinephrine; Female; Heart Rate; Humans; Hyd | 1990 |
Insulin-receptor interaction in the obese-hyperglycemic mouse. A model of insulin resistance.
Topics: Animals; Cell Fractionation; Cell Membrane; Electrophoresis, Disc; Genetics; Glucagon; Growth Hormon | 1973 |
Glycemic effects of solanine in rats.
Topics: Adrenalectomy; Animals; Blood Glucose; Chlorpromazine; Ergotamine; Female; Glucose Tolerance Test; G | 1967 |
Metabolic effects of pertussis sensitization in mice and rats.
Topics: Adipose Tissue; Adrenalectomy; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Epinephrine; | 1968 |
[Pharmacological study of the role of beta-adrenergic receptors in insulin secretion in the dog].
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anesthesia, Intravenous; Animals; Autoanalysi | 1970 |
The response of the sweat glands to -adrenergic stimulation.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Dermatitis, Atopic; | 1972 |
The postoperative intensive care after cardiac surgery in the neonate.
Topics: Acidosis; Alkalosis; Anti-Bacterial Agents; Blood Transfusion; Body Temperature; Digoxin; Diuretics; | 1973 |
Monoamines in the pancreatic islets of the mouse. 5-hydroxytryptamine as an intracellular modifier of insulin secretion, and the hypoglycaemic action of monoamine oxidase inhibitors.
Topics: 5-Hydroxytryptophan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Glucose; Glybu | 1971 |
The comparative glycemic effects of catecholamines in rats and mice.
Topics: Adrenalectomy; Animals; Blood Glucose; Epinephrine; Fasting; Hyperglycemia; Hypoglycemia; Insulin; I | 1971 |
Role of beta-adrenergic receptors in counterregulation to insulin-induced hypoglycemia.
Topics: Animals; Blood Glucose; Epinephrine; Fatty Acids, Nonesterified; Glucose; Glycerol; Humans; Hypoglyc | 1968 |