isoproterenol has been researched along with Hypertrophy in 136 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| " The SO2 content of the rat heart has been observed to substantially decrease during isoproterenol-induced hypertrophy." | 8.02 | Sulfur Dioxide Derivative Prevents the Prolongation of Action Potential During the Isoproterenol-Induced Hypertrophy of Rat Cardiomyocytes. ( Dalaman, U; Özdoğan, H; Şengül, SA; Sircan, AK; Yaraş, N, 2021) |
| "Endothelin-1 (ET1) is a vasoactive peptide that stimulates hypertrophy of vascular smooth muscle cells (VSMC) through diverse signaling pathways mediated by G(q)/G(i)/G(13) heterotrimeric G proteins." | 7.74 | Gbetagamma-mediated prostacyclin production and cAMP-dependent protein kinase activation by endothelin-1 promotes vascular smooth muscle cell hypertrophy through inhibition of glycogen synthase kinase-3. ( Dulin, NO; Hogarth, K; Sandbo, N; Taurin, S; Yau, DM, 2007) |
| " Celiprolol, a selective beta(1)-blocker, was reported to stimulate the expression of endothelial NO synthase (eNOS) in the heart, and NO levels have been demonstrated to be related to myocardial hypertrophy and heart failure." | 7.72 | Celiprolol, a vasodilatory beta-blocker, inhibits pressure overload-induced cardiac hypertrophy and prevents the transition to heart failure via nitric oxide-dependent mechanisms in mice. ( Asakura, M; Asano, Y; Asanuma, H; Hori, M; Kim, J; Kitakaze, M; Kitamura, S; Liao, Y; Minamino, T; Ogai, A; Sanada, S; Shintani, Y; Takashima, S; Tomoike, H, 2004) |
| "Chronic administration of isoproterenol (IPR) results in a marked hypertrophy and in the induction of a group of putative proline-rich polypeptides in the mouse parotid glands." | 7.72 | Early detection in saliva of polypeptides associated to isoproterenol-induced mouse parotid hypertrophy. ( Díaz, F; López Solís, R; Morales Bozo, I; Puente Díaz, M; Weis, UK, 2003) |
| "We investigated whether angiotensin II (Ang II) and endothelin-1(ET-1) are involved in submandibular hypertrophy in response to repeated treatment with isoproterenol (ISO) in rats." | 7.70 | Involvement of angiotensin II and endothelin-1 in the development of submandibular gland hypertrophy in response to isoproterenol in rats. ( Hayashi, K; Iwamoto, K; Kizawa, Y; Kusama, T; Murakami, H; Saito, K; Sano, M, 2000) |
| "Chronic administration of the beta-adrenergic receptor agonist isoproterenol results in parotid gland hypertrophy and hyperplasia." | 7.67 | Isoproterenol-mediated parotid gland hypertrophy is inhibited by effectors of 4 beta-galactosyltransferase. ( Humphreys-Beher, MG; Kidd, VJ; Marchase, RB; Schneyer, CA, 1987) |
| "Chronic isoproterenol treatment of rats results in hypertrophy and hyperplasia of the parotid gland." | 7.67 | Restoration of alpha-lactalbumin-inhibited rat parotid salivary gland hypertrophy and hyperplasia by agents specific for membrane glycoprotein N-acetylglucosamine. ( Humphreys-Beher, MG, 1989) |
| "Chronic treatment of rats with isoproterenol (IPR) induces mitosis and differentiation of intercalated duct cells, and mitosis and hypertrophy of endothelial cells of the microvasculature in the parotid gland." | 7.67 | Mitosis and hypertrophy of intercalated duct cells and endothelial cells in the isoproterenol-treated rat parotid gland. ( Hand, AR; Ho, B, 1985) |
| "Chronic administration of isoproterenol (ISO) produces hypertrophy of the rat heart and tibialis muscle." | 7.66 | Protein synthesis, amino acid uptake, and pools during isoproterenol-induced hypertrophy of the rat heart and tibialis muscle. ( Deshaies, Y; Leblanc, J; Willemot, J, 1981) |
| " chronic administration of isoproterenol (IPR) caused enlargement of the parotid and submandibular glands and the synthesis of apparently new proteins, probably by acinar cells." | 5.26 | The secretion of protein and of some electrolytes in response to alpha- and beta- adrenergic agonists by rat parotid and submandibular salivary glands enlarged by chronic treatment with isoproterenol. ( Abe, K; Dawes, C, 1980) |
| " Using isoproterenol, children with chronic otitis media with effusion demonstrated a blunted dynamic ciliary response at 2 and 3 hours relative to control (P = ." | 5.17 | Adenoid ciliostimulation in children with chronic otitis media. ( Andreoli, SM; Discolo, CM; Mulligan, RM; Schlosser, RJ; Wang, LF; White, DR, 2013) |
| " Here, we have investigated the effects and potential mechanisms of action of MgIG, with respect to myocardial fibrosis induced by isoproterenol (ISO) in mice." | 4.98 | Inhibition of myocardial hypertrophy by magnesium isoglycyrrhizinate through the TLR4/NF-κB signaling pathway in mice. ( Chu, L; Han, X; Ma, D; Song, T; Zhang, J; Zhang, X; Zhang, Y, 2018) |
| " After that, the use of the chemical compound was tested in the treatment of pregnant mice previously subjected to isoproterenol (fetal hypertrophy model) on the fifth day post coitus." | 4.31 | The sodium borate relieves the hypertrophic damage induced during pregnancy, it improves contractibility, reduces oxidative stress and stimulates cell proliferation. ( Contreras-Ramos, A; Cruz-Hernández, M; Díaz-Rosas, G; López-Torres, A; Ortega-Camarillo, C; Pedraza-Galeana, A, 2023) |
| " Although hypertrophy is a high-priority target, we found that hiPSC-CMs were systematically unresponsive to hypertrophic signals such as the α-adrenoceptor (αAR) agonist phenylephrine (PE) compared to hESC-CMs." | 3.80 | Aberrant α-adrenergic hypertrophic response in cardiomyocytes from human induced pluripotent cells. ( Amisten, S; Arányi, T; Denning, C; Dolatshad, NF; Földes, G; Harding, SE; Ketteler, R; Kodagoda, T; Kolker, L; Kriston-Vizi, J; Leja, T; Matsa, E; Mioulane, M; Schneider, MD; Vauchez, K, 2014) |
| "Chronic isoproterenol treatment causes hypertrophy and hyperplasia of rodent salivary glands." | 3.79 | Isoproterenol modulates matrix metalloproteinase-2 (MMP-2) and its tissue inhibitor-2 (TIMP-2) in rat parotid gland. ( D'Amico, F; Malaponte, G; Mangano, K; Mazzarino, MC; Skarmoutsou, E, 2013) |
| " Activation of calcineurin occurs downstream of β-adrenergic signaling and is required for isoproterenol-induced myocardial hypertrophy." | 3.78 | FHL2 binds calcineurin and represses pathological cardiac growth. ( Gillette, TG; Hill, JA; Hojayev, B; Rothermel, BA, 2012) |
| " In addition to developmental changes, we found that Epac gene expression was upregulated in myocardial hypertrophy induced by chronic isoproterenol infusion or pressure overload by transverse aortic banding." | 3.74 | Developmental changes in gene expression of Epac and its upregulation in myocardial hypertrophy. ( Bai, Y; Baljinnyam, E; Hirotani, S; Ishikawa, Y; Minamisawa, S; Okumura, S; Sato, M; Ulucan, C; Wang, X, 2007) |
| "Endothelin-1 (ET1) is a vasoactive peptide that stimulates hypertrophy of vascular smooth muscle cells (VSMC) through diverse signaling pathways mediated by G(q)/G(i)/G(13) heterotrimeric G proteins." | 3.74 | Gbetagamma-mediated prostacyclin production and cAMP-dependent protein kinase activation by endothelin-1 promotes vascular smooth muscle cell hypertrophy through inhibition of glycogen synthase kinase-3. ( Dulin, NO; Hogarth, K; Sandbo, N; Taurin, S; Yau, DM, 2007) |
| "Experimental mouse parotid hypertrophy has been associated with the expression of a number of isoproterenol-induced salivary proline-rich polypeptides (IISPs)." | 3.73 | Codominant expression of genes coding for different sets of inducible salivary polypeptides associated with parotid hypertrophy in two inbred mouse strains. ( Kemmerling, U; López-Solís, RO, 2005) |
| "Chronic administration of isoproterenol (IPR) results in a marked hypertrophy and in the induction of a group of putative proline-rich polypeptides in the mouse parotid glands." | 3.72 | Early detection in saliva of polypeptides associated to isoproterenol-induced mouse parotid hypertrophy. ( Díaz, F; López Solís, R; Morales Bozo, I; Puente Díaz, M; Weis, UK, 2003) |
| " Celiprolol, a selective beta(1)-blocker, was reported to stimulate the expression of endothelial NO synthase (eNOS) in the heart, and NO levels have been demonstrated to be related to myocardial hypertrophy and heart failure." | 3.72 | Celiprolol, a vasodilatory beta-blocker, inhibits pressure overload-induced cardiac hypertrophy and prevents the transition to heart failure via nitric oxide-dependent mechanisms in mice. ( Asakura, M; Asano, Y; Asanuma, H; Hori, M; Kim, J; Kitakaze, M; Kitamura, S; Liao, Y; Minamino, T; Ogai, A; Sanada, S; Shintani, Y; Takashima, S; Tomoike, H, 2004) |
| " In the absence of FHL2, however, cardiac hypertrophy resulting from chronic infusion of isoproterenol is exaggerated (59% versus 20% increase in heart weight/body weight in FHL null versus wild-type mice; P<0." | 3.71 | Cardiac-specific LIM protein FHL2 modifies the hypertrophic response to beta-adrenergic stimulation. ( Bassel-Duby, R; Kong, Y; Li, X; Richardson, JA; Rothermel, B; Shelton, JM; Williams, RS, 2001) |
| "We investigated whether angiotensin II (Ang II) and endothelin-1(ET-1) are involved in submandibular hypertrophy in response to repeated treatment with isoproterenol (ISO) in rats." | 3.70 | Involvement of angiotensin II and endothelin-1 in the development of submandibular gland hypertrophy in response to isoproterenol in rats. ( Hayashi, K; Iwamoto, K; Kizawa, Y; Kusama, T; Murakami, H; Saito, K; Sano, M, 2000) |
| " Chronic injections of the beta-adrenergic receptor agonist, isoproterenol, result in a non-neoplastic hypertrophy and hyperplasia of the rat parotid gland." | 3.70 | Changes in the expression of extracellular matrix (ECM) and matrix metalloproteinases (MMP) of proliferating rat parotid acinar cells. ( Brinkley, LL; Broverman, RL; da Silveira, A; Humphreys-Beher, MG; Kerr, M; Macauley, SP; Nguyen, KH; Schultz, GS; Tarnuzzer, RW; Yamamoto, H; Zeng, T, 1998) |
| "Chronic treatment of mice and rats with isoproterenol (IPR) causes marked hypertrophy and hyperplasia of the salivary glands, and alters the expression of several secretory proteins." | 3.69 | Quantitative immunocytochemical study of secretory protein expression in parotid glands of rats chronically treated with isoproterenol. ( Hand, AR; Vugman, I, 1995) |
| " Myosin HC synthesis also appeared to be independently regulated during cardiomyocyte atrophy induced by the calcium channel blocker nifedipine." | 3.69 | Myosin heavy chain synthesis is independently regulated in hypertrophy and atrophy of isolated adult cardiac myocytes. ( Andersen, LC; Clark, WA; LaPres, JJ; Rudnick, SJ, 1994) |
| " Administration of the beta-adrenergic agonist isoproterenol for 4 days, which caused a marked hypertrophy of the submandibular gland, had no effect on the structure, weight, or cystatin content of the exorbital lacrimal gland." | 3.68 | Immunofluorescence localization of cystatins in human lacrimal gland and in the exorbital lacrimal gland of the rat. ( Barka, T; Honda, Y; Ogawa, K; Takahashi, M, 1992) |
| "Chronic injections of epidermal growth factor (EGF) or the beta-adrenergic receptor agonist isoprenaline resulted in rat parotid gland hypertrophy and hyperplasia." | 3.68 | A novel mechanism for isoprenaline-stimulated proliferation of rat parotid acinar cells involving the epidermal growth factor receptor and cell surface galactosyltransferase. ( Dunn, WA; Humphreys-Beher, MG; Purushotham, KR; Schneyer, CA, 1992) |
| "Chronic injection of isoproterenol into mice resulted in hypertrophy and hyperplasia of the parotid gland." | 3.68 | Regulation of cell-surface galactosyltransferase in isoproterenol-treated mouse parotid glands. ( Humphreys-Beher, MG; Koller, MM; Maeda, N; Purushotham, KR, 1991) |
| "Isoproterenol, a beta-adrenergic receptor agonist, causes hypertrophy and hyperplasia of the rat parotid gland." | 3.67 | Alpha-lactalbumin acts as a bimodal regulator of rat parotid acinar cell growth. ( Humphreys-Beher, MG; Schneyer, CA; Zelles, T, 1987) |
| "The present study was carried out to determine the beta-receptor subtype responsible for the hypertrophy and dysfunction of parotid glands in rats chronically treated with isoproterenol (ISP)." | 3.67 | Hypertrophy and dysfunction of parotid gland induced by chronic stimulation of beta 1-adrenergic receptors. ( Ohshika, H; Suzuki, Y, 1985) |
| "Chronic isoproterenol treatment of rats results in hypertrophy and hyperplasia of the parotid gland." | 3.67 | Restoration of alpha-lactalbumin-inhibited rat parotid salivary gland hypertrophy and hyperplasia by agents specific for membrane glycoprotein N-acetylglucosamine. ( Humphreys-Beher, MG, 1989) |
| "Chronic administration of isoproterenol (ISO) produces hypertrophy of the rat heart and tibialis muscle." | 3.66 | Protein synthesis, amino acid uptake, and pools during isoproterenol-induced hypertrophy of the rat heart and tibialis muscle. ( Deshaies, Y; Leblanc, J; Willemot, J, 1981) |
| "The responsiveness towards catecholamines of normal and lipomatous fat cells of two male subjects suffering from multiple symmetric lipomatosis has been studied by means of a newly developed bioluminescent method for microdetermination of glycerol." | 3.66 | Adrenergic regulation of fat-cell lipolysis in multiple symmetric lipomatosis. ( Kather, H; Schröder, F, 1982) |
| "Personal observations made on the model of isoproterenol-stimulated DNA synthesis have pointed out the following: 1) cell hypertrophy precedes constantly the onset of DNA synthesis; 2) the length of the G1 phase is mass-dependent; 3) accumulation of ribosomes is needed for cell progress through G1; 4) ribosomal protein synthesis is involved in cell growth activation." | 3.65 | Molecular basis of a control mechanism of DNA synthesis in mammalian cells. ( Novi, AM, 1976) |
| " Induction of cardiac connective tissue hypertrophy with isoproterenol inverted the ratio of slow to fast ferritin in female rats, while iron administration along with isoproterenol restored this to normal." | 3.65 | Sex difference in distribution and iron responsiveness of the two ferritins of rat cardiac and skeletal muscle. ( Linder, MC; Munro, HN; Vulimiri, L, 1977) |
| " Cardiomegaly has been produced in rats by sideropenic anaemia, by isoprenaline or thyroxine or by the application of both drugs, by artificial increase in resistance to blood flow and by long-term adaptation to hypoxia and physical stress." | 3.65 | The growth of the muscular and collagenous parts of the rat heart in various forms of cardiomegaly. ( Bartosová, D; Chvapil, M; Korecký, B; Poupa, O; Rakusan, K; Turek, Z; Vízek, M, 1969) |
| "Hypertrophy was restored on NOS or protein kinase G inhibition." | 1.40 | Enhanced expression of β3-adrenoceptors in cardiac myocytes attenuates neurohormone-induced hypertrophic remodeling through nitric oxide synthase. ( Balligand, JL; Beauloye, C; Belge, C; Bertrand, L; Dessy, C; Dubois-Deruy, E; Esfahani, H; Götz, KR; Hamelet, J; Hammond, J; Herijgers, P; Hilfiker-Kleiner, D; Iaccarino, G; Jnaoui, K; Langin, D; Lobysheva, I; Manoury, B; Markl, A; Nikolaev, VO; Pouleur, AC; Tavernier, G; Vanderper, A, 2014) |
| "Isoproterenol was administered twice to female Wistar rats (170 mg/kg, s." | 1.39 | Ventricular repolarization in a rat model of global heart failure. ( Kharin, S; Krandycheva, V; Shmakov, D; Shumikhin, K; Sobolev, A; Strelkova, M, 2013) |
| "Cardiomyocyte hypertrophy is the cellular response that mediates pathologic enlargement of the heart." | 1.39 | Intrinsic-mediated caspase activation is essential for cardiomyocyte hypertrophy. ( Abdul-Ghani, M; Brunette, S; Dick, SA; Fernando, P; Megeney, LA; Putinski, C; Stiles, R, 2013) |
| " Experimentally, chronic administration of the β-AR agonist isoproterenol (ISO) has been most commonly used to model β-AR-induced cardiac remodeling." | 1.37 | Distinct actions of intermittent and sustained β-adrenoceptor stimulation on cardiac remodeling. ( Chen, C; Fu, Y; Li, Z; Ma, X; Shen, Q; Song, Y; Zhang, Y, 2011) |
| "Dobutamine was also found to be clearly stronger than salbutamol as an inducer of polypeptides C-G." | 1.31 | Cell-enlargement-related polypeptides are induced via beta(1)-adrenoceptors in mouse parotids. ( Alliende, C; González, MJ; López Solís, RO; Peña y Lillo, S, 2000) |
| " Trichloroacetic acid-soluble proline-rich proteins were isolated from parotid glands at a dosage of 4." | 1.27 | Isoprenaline-induced changes in rat parotid and submandibular glands are age- and dosage-dependent. ( Humphreys-Beher, MG, 1984) |
| " In comparison with control animals, the enlarged submandibular glands of rats subjected to orthodontic treatment secreted additional proteins identical with those secreted by glands enlarged by chronic administration of isoproterenol." | 1.27 | The effects of upper incisor separation on the submandibular and sublingual glands of rats. ( Abe, K; Ichikawa, K; Ishibashi, K; Itoh, T; Kamogashira, K; Matsumoto, M; Yanabu, M, 1988) |
| " chronic administration of isoproterenol (IPR) caused enlargement of the parotid and submandibular glands and the synthesis of apparently new proteins, probably by acinar cells." | 1.26 | The secretion of protein and of some electrolytes in response to alpha- and beta- adrenergic agonists by rat parotid and submandibular salivary glands enlarged by chronic treatment with isoproterenol. ( Abe, K; Dawes, C, 1980) |
| "The enzyme content and the secretory behaviour of normal rat salivary glands were compared with these properties in glands made hypertrophic and hyperplastic by the chronic administration of isoproterenol." | 1.26 | Secretory behaviour of hypertrophic and hyperplastic salivary gland. ( Barka, T; Burke, GT, 1977) |
| "The hypertrophy was due to an increase in size of mucous cells, which were filled with secretion." | 1.26 | The development and persistence of bronchialgland hypertrophy and goblet-cell hyperplasia in the pig after injection of isoprenaline. ( Baskerville, A, 1976) |
| " Metoprolol, a selective beta-1 receptor antagonist, significantly inhibited the glandular enlargement induced by dobutamine or isoproterenol and produced a parallel shift in the isoproterenol dose-response curve." | 1.26 | Adrenergic beta receptors mediating submandibular salivary gland hypertrophy in the rat. ( Brenner, GM; Wulf, RG, 1981) |
| " Chronic administration of IPR led to an increase in the frequency of acinar cells." | 1.26 | Stimulated growth of submandibular gland. ( Barka, T; Van Der Noen, H, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 69 (50.74) | 18.7374 |
| 1990's | 17 (12.50) | 18.2507 |
| 2000's | 22 (16.18) | 29.6817 |
| 2010's | 23 (16.91) | 24.3611 |
| 2020's | 5 (3.68) | 2.80 |
| Authors | Studies |
|---|---|
| Flamant, M | 1 |
| Mougenot, N | 1 |
| Balse, E | 1 |
| Le Fèvre, L | 1 |
| Atassi, F | 1 |
| Gautier, EL | 1 |
| Le Goff, W | 1 |
| Keck, M | 1 |
| Nadaud, S | 1 |
| Combadière, C | 1 |
| Boissonnas, A | 1 |
| Pavoine, C | 1 |
| Dalaman, U | 1 |
| Özdoğan, H | 1 |
| Sircan, AK | 1 |
| Şengül, SA | 1 |
| Yaraş, N | 1 |
| Shi, Y | 1 |
| Zhao, L | 1 |
| Wang, J | 1 |
| Liu, S | 2 |
| Zhang, Y | 4 |
| Qin, Q | 1 |
| Díaz-Rosas, G | 1 |
| Cruz-Hernández, M | 1 |
| Ortega-Camarillo, C | 1 |
| Pedraza-Galeana, A | 1 |
| López-Torres, A | 1 |
| Contreras-Ramos, A | 1 |
| Mei, Y | 1 |
| Liu, B | 1 |
| Su, H | 1 |
| Zhang, H | 1 |
| Liu, F | 1 |
| Ke, Q | 1 |
| Sun, X | 2 |
| Tan, W | 2 |
| Tang, F | 1 |
| Jiang, Z | 1 |
| Long, J | 1 |
| Chu, C | 1 |
| Ma, D | 1 |
| Zhang, J | 1 |
| Zhang, X | 1 |
| Han, X | 1 |
| Song, T | 1 |
| Chu, L | 1 |
| Li, R | 1 |
| Yan, G | 1 |
| Zhang, Q | 1 |
| Jiang, Y | 1 |
| Sun, H | 1 |
| Hu, Y | 1 |
| Sun, J | 1 |
| Xu, B | 1 |
| Krandycheva, V | 1 |
| Kharin, S | 1 |
| Strelkova, M | 1 |
| Shumikhin, K | 1 |
| Sobolev, A | 1 |
| Shmakov, D | 1 |
| Morgan-Bathke, M | 1 |
| Lin, HH | 1 |
| Chibly, AM | 1 |
| Zhang, W | 1 |
| Chen, CH | 1 |
| Flodby, P | 1 |
| Borok, Z | 1 |
| Wu, R | 1 |
| Arnett, D | 1 |
| Klein, RR | 1 |
| Ann, DK | 1 |
| Limesand, KH | 1 |
| Putinski, C | 1 |
| Abdul-Ghani, M | 1 |
| Stiles, R | 1 |
| Brunette, S | 1 |
| Dick, SA | 1 |
| Fernando, P | 1 |
| Megeney, LA | 1 |
| Belge, C | 1 |
| Hammond, J | 1 |
| Dubois-Deruy, E | 1 |
| Manoury, B | 1 |
| Hamelet, J | 1 |
| Beauloye, C | 1 |
| Markl, A | 1 |
| Pouleur, AC | 1 |
| Bertrand, L | 1 |
| Esfahani, H | 1 |
| Jnaoui, K | 1 |
| Götz, KR | 1 |
| Nikolaev, VO | 1 |
| Vanderper, A | 1 |
| Herijgers, P | 1 |
| Lobysheva, I | 1 |
| Iaccarino, G | 1 |
| Hilfiker-Kleiner, D | 1 |
| Tavernier, G | 1 |
| Langin, D | 1 |
| Dessy, C | 1 |
| Balligand, JL | 1 |
| Voelkl, J | 1 |
| Alesutan, I | 1 |
| Pakladok, T | 1 |
| Viereck, R | 1 |
| Feger, M | 1 |
| Mia, S | 1 |
| Schönberger, T | 1 |
| Noegel, AA | 1 |
| Gawaz, M | 1 |
| Lang, F | 1 |
| Ji, XX | 1 |
| Song, XL | 1 |
| Qian, W | 1 |
| Yu, XL | 1 |
| Zhu, JY | 1 |
| Mielcarek, M | 1 |
| Bondulich, MK | 1 |
| Inuabasi, L | 1 |
| Franklin, SA | 1 |
| Muller, T | 1 |
| Bates, GP | 1 |
| Földes, G | 1 |
| Matsa, E | 1 |
| Kriston-Vizi, J | 1 |
| Leja, T | 1 |
| Amisten, S | 1 |
| Kolker, L | 1 |
| Kodagoda, T | 1 |
| Dolatshad, NF | 1 |
| Mioulane, M | 1 |
| Vauchez, K | 1 |
| Arányi, T | 1 |
| Ketteler, R | 1 |
| Schneider, MD | 1 |
| Denning, C | 1 |
| Harding, SE | 1 |
| Irie, T | 1 |
| Sips, PY | 1 |
| Kai, S | 1 |
| Kida, K | 1 |
| Ikeda, K | 1 |
| Hirai, S | 1 |
| Moazzami, K | 1 |
| Jiramongkolchai, P | 1 |
| Bloch, DB | 1 |
| Doulias, PT | 1 |
| Armoundas, AA | 1 |
| Kaneki, M | 1 |
| Ischiropoulos, H | 1 |
| Kranias, E | 1 |
| Bloch, KD | 2 |
| Stamler, JS | 1 |
| Ichinose, F | 1 |
| Yeh, YL | 1 |
| Tsai, HI | 1 |
| Cheng, SM | 1 |
| Pai, P | 1 |
| Ho, TJ | 1 |
| Chen, RJ | 1 |
| Lai, CH | 1 |
| Huang, PJ | 1 |
| Padma, VV | 1 |
| Huang, CY | 1 |
| Deshpande, M | 1 |
| Mali, VR | 1 |
| Pan, G | 1 |
| Xu, J | 1 |
| Yang, XP | 1 |
| Thandavarayan, RA | 1 |
| Palaniyandi, SS | 1 |
| Chowdhury, D | 1 |
| Kumar, D | 1 |
| Bhadra, U | 1 |
| Devi, TA | 1 |
| Bhadra, MP | 1 |
| Klos, M | 1 |
| Mundada, L | 1 |
| Banerjee, I | 1 |
| Morgenstern, S | 1 |
| Myers, S | 1 |
| Leone, M | 1 |
| Kleid, M | 1 |
| Herron, T | 1 |
| Devaney, E | 1 |
| El-Armouche, A | 1 |
| Wittköpper, K | 1 |
| Degenhardt, F | 1 |
| Weinberger, F | 1 |
| Didié, M | 1 |
| Melnychenko, I | 1 |
| Grimm, M | 1 |
| Peeck, M | 1 |
| Zimmermann, WH | 1 |
| Unsöld, B | 1 |
| Hasenfuss, G | 1 |
| Dobrev, D | 1 |
| Eschenhagen, T | 1 |
| Wu, G | 1 |
| Wang, H | 1 |
| Yang, J | 1 |
| Yang, Y | 1 |
| Liu, C | 1 |
| Jing, L | 1 |
| Wong, TM | 1 |
| Bell, D | 2 |
| Zhao, Y | 1 |
| McMaster, B | 1 |
| McHenry, EM | 1 |
| Wang, X | 2 |
| Kelso, EJ | 1 |
| McDermott, BJ | 2 |
| Cheng, YS | 1 |
| Dai, DZ | 1 |
| Dai, Y | 1 |
| de Barros, R | 1 |
| Zornoff, LA | 1 |
| Ribeiro, HB | 1 |
| Okoshi, MP | 1 |
| Padovani, CR | 1 |
| Aragon, FF | 1 |
| Cicogna, AC | 1 |
| Taniguchi, M | 1 |
| Ono, N | 1 |
| Hayashi, A | 1 |
| Yakura, Y | 1 |
| Takeya, H | 1 |
| Ma, X | 1 |
| Song, Y | 1 |
| Chen, C | 1 |
| Fu, Y | 1 |
| Shen, Q | 1 |
| Li, Z | 1 |
| Kaminski, KA | 1 |
| Dziemidowicz, M | 1 |
| Litvinovich, S | 1 |
| Bonda, T | 1 |
| Ptaszynska, K | 1 |
| Kozuch, M | 1 |
| Taranta, A | 1 |
| Musial, WJ | 1 |
| Winnicka, MM | 1 |
| Hojayev, B | 1 |
| Rothermel, BA | 1 |
| Gillette, TG | 1 |
| Hill, JA | 1 |
| D'Amico, F | 1 |
| Skarmoutsou, E | 1 |
| Mangano, K | 1 |
| Malaponte, G | 1 |
| Mazzarino, MC | 1 |
| Andreoli, SM | 1 |
| Schlosser, RJ | 1 |
| Wang, LF | 1 |
| Mulligan, RM | 1 |
| Discolo, CM | 1 |
| White, DR | 1 |
| López Solís, R | 1 |
| Puente Díaz, M | 1 |
| Morales Bozo, I | 1 |
| Weis, UK | 1 |
| Díaz, F | 1 |
| SELYE, H | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multi-centre Randomized, Placebo-controlled Trial of Mirabegron, a New beta3-adrenergic Receptor Agonist on Left Ventricular Mass and Diastolic Function in Patients With Structural Heart Disease[NCT02599480] | Phase 2 | 296 participants (Actual) | Interventional | 2016-04-30 | Active, not recruiting | ||
| Methods to Identify and Treat Severe Asthma Patients Project 1: GSNOR Phenotyping and GSNO Challenge[NCT03926741] | Early Phase 1 | 60 participants (Anticipated) | Interventional | 2019-04-30 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for isoproterenol and Hypertrophy
| Article | Year |
|---|---|
Inhibition of myocardial hypertrophy by magnesium isoglycyrrhizinate through the TLR4/NF-κB signaling pathway in mice.
Topics: Animals; Anti-Inflammatory Agents; Atrial Natriuretic Factor; bcl-2-Associated X Protein; Creatine K | 2018 |
Enlargement of salivary glands. Review of the literature.
Topics: Animal Feed; Animals; Hormones; Humans; Hypertrophy; Incisor; Isoproterenol; Mice; Parotid Gland; Pe | 1972 |
1 trial available for isoproterenol and Hypertrophy
| Article | Year |
|---|---|
Adenoid ciliostimulation in children with chronic otitis media.
Topics: Adenoidectomy; Adenoids; Child; Child, Preschool; Chronic Disease; Female; Hospitals, Pediatric; Hum | 2013 |
133 other studies available for isoproterenol and Hypertrophy
| Article | Year |
|---|---|
Early activation of the cardiac CX3CL1/CX3CR1 axis delays β-adrenergic-induced heart failure.
Topics: Adrenergic beta-Agonists; Animals; Cell Communication; Cell Proliferation; Cells, Cultured; Chemokin | 2021 |
Sulfur Dioxide Derivative Prevents the Prolongation of Action Potential During the Isoproterenol-Induced Hypertrophy of Rat Cardiomyocytes.
Topics: Action Potentials; Animals; Hypertrophy; Isoproterenol; Myocytes, Cardiac; Rats; Rats, Wistar; Sulfu | 2021 |
The selective NLRP3 inflammasome inhibitor MCC950 improves isoproterenol-induced cardiac dysfunction by inhibiting cardiomyocyte senescence.
Topics: Animals; Furans; Heart Diseases; Heterocyclic Compounds, 4 or More Rings; Hypertrophy; Inflammasomes | 2022 |
The sodium borate relieves the hypertrophic damage induced during pregnancy, it improves contractibility, reduces oxidative stress and stimulates cell proliferation.
Topics: Animals; Cardiotoxicity; Cell Proliferation; Female; Glutathione; Hypertrophy; Isoproterenol; Mice; | 2023 |
Isosteviol sodium protects the cardiomyocyte response associated with the SIRT1/PGC-1α pathway.
Topics: Animals; Carbazoles; Cardiotonic Agents; Cell Line; Diterpenes, Kaurane; DNA, Mitochondrial; Glucose | 2020 |
[Effect of Shexiang Baoxin Pills on isoprenaline-induced myocardial cell hypertrophy and Cx43 expression].
Topics: Connexin 43; Drugs, Chinese Herbal; Heart Diseases; Humans; Hypertrophy; Isoproterenol | 2017 |
miR-145 inhibits isoproterenol-induced cardiomyocyte hypertrophy by targeting the expression and localization of GATA6.
Topics: 3' Untranslated Regions; Active Transport, Cell Nucleus; Adrenergic beta-Agonists; Animals; Base Seq | 2013 |
Ventricular repolarization in a rat model of global heart failure.
Topics: Action Potentials; Animals; Cardiac Output; Disease Models, Animal; Electrocardiography; Female; Hea | 2013 |
Deletion of ATG5 shows a role of autophagy in salivary homeostatic control.
Topics: Acinar Cells; Aging; Amylases; Animals; Apoptosis; Aquaporin 5; Autophagy; Autophagy-Related Protein | 2013 |
Intrinsic-mediated caspase activation is essential for cardiomyocyte hypertrophy.
Topics: Angiotensin II; Animals; Animals, Newborn; Apoptosis; Bronchodilator Agents; Cardiomegaly; Caspase 3 | 2013 |
Enhanced expression of β3-adrenoceptors in cardiac myocytes attenuates neurohormone-induced hypertrophic remodeling through nitric oxide synthase.
Topics: Angiotensin II; Animals; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Disease | 2014 |
Annexin A7 deficiency potentiates cardiac NFAT activity promoting hypertrophic signaling.
Topics: Adrenergic beta-Agonists; Animals; Annexin A7; Aorta; Blotting, Western; Calcium-Binding Proteins; C | 2014 |
Effects and mechanism of action of ligustrazine on isoprenaline-induced cardiomyocyte hypertrophy.
Topics: Animals; Calcium Channel Blockers; Calcium Signaling; Cardiomegaly; Cardiotonic Agents; Cells, Cultu | 2014 |
The Huntington's disease-related cardiomyopathy prevents a hypertrophic response in the R6/2 mouse model.
Topics: Adrenergic beta-Antagonists; Animals; Brain-Derived Neurotrophic Factor; Cardiomyopathies; Collagen | 2014 |
Aberrant α-adrenergic hypertrophic response in cardiomyocytes from human induced pluripotent cells.
Topics: Adrenergic Agents; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; | 2014 |
S-Nitrosylation of Calcium-Handling Proteins in Cardiac Adrenergic Signaling and Hypertrophy.
Topics: Adrenergic beta-Agonists; Aldehyde Oxidoreductases; Animals; Calcium; Calcium-Binding Proteins; Cell | 2015 |
Mechanism of Taiwan Mingjian Oolong Tea to Inhibit Isoproterenol-Induced Hypertrophy and Apoptosis in Cardiomyoblasts.
Topics: Animals; Apoptosis; Camellia sinensis; Cardiotonic Agents; Cell Proliferation; Cell Survival; Cells, | 2016 |
Increased 4-hydroxy-2-nonenal-induced proteasome dysfunction is correlated with cardiac damage in streptozotocin-injected rats with isoproterenol infusion.
Topics: Aldehyde Dehydrogenase, Mitochondrial; Aldehydes; Animals; Cell Line; Diabetes Mellitus, Experimenta | 2016 |
Prohibitin confers cytoprotection against ISO-induced hypertrophy in H9c2 cells via attenuation of oxidative stress and modulation of Akt/Gsk-3β signaling.
Topics: Animals; Cytoprotection; Glycogen Synthase Kinase 3 beta; Hypertrophy; Isoproterenol; Oxidative Stre | 2017 |
Altered myocyte contractility and calcium homeostasis in alpha-myosin heavy chain point mutations linked to familial dilated cardiomyopathy.
Topics: Animals; Calcium; Cardiomyopathy, Dilated; Homeostasis; Humans; Hypertrophy; Isoproterenol; Kinetics | 2017 |
Phosphatase inhibitor-1-deficient mice are protected from catecholamine-induced arrhythmias and myocardial hypertrophy.
Topics: Adrenergic beta-Agonists; Animals; Arrhythmias, Cardiac; Calcium; Calcium-Binding Proteins; Catechol | 2008 |
kappa-Opioid receptor stimulation inhibits augmentation of Ca(2+) transient and hypertrophy induced by isoprenaline in neonatal rat ventricular myocytes - Role of CaMKIIdelta(B).
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic | 2008 |
SRIF receptor subtype expression and involvement in positive and negative contractile effects of somatostatin-14 (SRIF-14) in ventricular cardiomyocytes.
Topics: Animals; Gene Expression Regulation; Heart Ventricles; Hypertrophy; Isoproterenol; Male; Myocardial | 2008 |
Isoproterenol disperses distribution of NADPH oxidase, MMP-9, and pPKCepsilon in the heart, which are mitigated by endothelin receptor antagonist CPU0213.
Topics: Animals; Cardiotonic Agents; Endothelin Receptor Antagonists; Gene Expression Regulation; Guanidines | 2009 |
Hypertrophied myocardium is more dependent on extracellular calcium than the normal cardiac muscle.
Topics: Animals; Blood Pressure; Calcium; Extracellular Space; Hypertrophy; Isometric Contraction; Isoproter | 2010 |
Effect of dibutyryl cyclic adenosine monophosphate on the gene expression of plasminogen activator inhibitor-1 and tissue factor in adipocytes.
Topics: 3T3-L1 Cells; Adenylyl Cyclases; Adipocytes; Adrenergic beta-Agonists; Animals; Bucladesine; Cilosta | 2011 |
Distinct actions of intermittent and sustained β-adrenoceptor stimulation on cardiac remodeling.
Topics: Adrenergic beta-Agonists; Animals; Echocardiography; Fibrosis; Heart Rate; Hypertrophy; Infusion Pum | 2011 |
Interleukin 6 is not necessary for STAT3 phosphorylation and myocardial hypertrophy following short term beta-adrenergic stimulation.
Topics: Adrenergic beta-Agonists; Animals; Hypertrophy; Interleukin-6; Isoproterenol; Male; Mice; Mice, Inbr | 2012 |
FHL2 binds calcineurin and represses pathological cardiac growth.
Topics: Animals; Calcineurin; Cardiotonic Agents; Cell Line; Cells, Cultured; Gene Deletion; Gene Expression | 2012 |
Isoproterenol modulates matrix metalloproteinase-2 (MMP-2) and its tissue inhibitor-2 (TIMP-2) in rat parotid gland.
Topics: Adrenergic beta-Agonists; Animals; Cell Proliferation; Female; Hyperplasia; Hypertrophy; Immunohisto | 2013 |
Early detection in saliva of polypeptides associated to isoproterenol-induced mouse parotid hypertrophy.
Topics: Animals; Biomarkers; Cell Division; Hypertrophy; Isoproterenol; Male; Mice; Parotid Gland; Peptides; | 2003 |
Excessive stimulation of salivary gland growth by isoproterenol.
Topics: Animals; Hypertrophy; Isoproterenol; Rats; Salivary Gland Diseases; Salivary Glands; Sympathomimetic | 1961 |
Asymptomatic enlargement of the parotid glands due to the use of isoproterenol.
Topics: Disease; Humans; Hypertrophy; Isoproterenol; Parotid Diseases; Parotid Gland | 1961 |
Salivary gland changes after isoproterenol-induced enlargement.
Topics: Hypertrophy; Isoproterenol; Salivary Glands; Sympathomimetics | 1962 |
STUDIES ON THE SALIVARY GLAND HYPERTROPHY INDUCED IN RATS BY ISOPRENALINE.
Topics: Hyperplasia; Hypertrophy; Isoproterenol; Parotid Gland; Pharmacology; Rats; Research; Salivary Gland | 1964 |
SYNERGISTIC AUTONOMIC NERVOUS REGULATION OF ACCELERATED SALIVARY GLAND GROWTH IN RATS.
Topics: Denervation; Hypertrophy; Hypophysectomy; Incisor; Isoproterenol; Pancreatic Extracts; Parasympathet | 1964 |
ENLARGEMENT OF THE RAT'S SALIVARY GLANDS AND SALIVARY CALCULUS FORMATION INDUCED WITH ISOPRENALINE.
Topics: Calcinosis; Hyperplasia; Hypertrophy; Isoproterenol; Rats; Research; Salivary Calculi; Salivary Glan | 1964 |
INDUCED CELL PROLIFERATION: THE EFFECT OF ISOPROTERENOL.
Topics: Autoradiography; Cell Division; Cell Proliferation; DNA; Hyperplasia; Hypertrophy; Isoproterenol; Ki | 1965 |
HEMODYNAMICS DURING THE CHRONIC STAGE OF MYOCARDIAL DAMAGE CAUSED BY ISOPROTERENOL.
Topics: Blood Circulation; Blood Pressure; Body Weight; Cardiac Output; Heart Diseases; Heart Rate; Hemodyna | 1964 |
Expression of constitutively active guanylate cyclase in cardiomyocytes inhibits the hypertrophic effects of isoproterenol and aortic constriction on mouse hearts.
Topics: Adenylyl Cyclases; Animals; Aorta; Blood Pressure; Blotting, Northern; COS Cells; Cyclic GMP; DNA, C | 2003 |
Phosphorylation of eukaryotic translation initiation factor 2Bepsilon by glycogen synthase kinase-3beta regulates beta-adrenergic cardiac myocyte hypertrophy.
Topics: Adenoviridae; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Animals, Newborn; Atri | 2004 |
Cardiomyocyte-specific overexpression of nitric oxide synthase 3 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction.
Topics: Adrenergic beta-Agonists; Animals; Enzyme Induction; Fibrosis; Humans; Hypertrophy; Hypertrophy, Lef | 2004 |
Celiprolol, a vasodilatory beta-blocker, inhibits pressure overload-induced cardiac hypertrophy and prevents the transition to heart failure via nitric oxide-dependent mechanisms in mice.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Cardiomegaly; Celiprol | 2004 |
Effects of rosiglitazone and interactions with growth-regulating factors in ventricular cell hypertrophy.
Topics: Animals; Cell Survival; Cells, Cultured; Culture Media; Culture Media, Serum-Free; Dose-Response Rel | 2005 |
Codominant expression of genes coding for different sets of inducible salivary polypeptides associated with parotid hypertrophy in two inbred mouse strains.
Topics: Adrenergic beta-Agonists; Animals; Gene Expression Regulation; Hypertrophy; Isoproterenol; Mice; Mic | 2005 |
Extracellular signal-regulated kinase pathway is differentially involved in beta-agonist-induced hypertrophy in slow and fast muscles.
Topics: Adrenergic beta-Agonists; Animals; Cell Cycle Proteins; Cell Line; Clenbuterol; Disease Models, Anim | 2007 |
Gbetagamma-mediated prostacyclin production and cAMP-dependent protein kinase activation by endothelin-1 promotes vascular smooth muscle cell hypertrophy through inhibition of glycogen synthase kinase-3.
Topics: Adrenergic beta-Agonists; Animals; Autocrine Communication; Cyclic AMP-Dependent Protein Kinases; Cy | 2007 |
Developmental changes in gene expression of Epac and its upregulation in myocardial hypertrophy.
Topics: Adenylyl Cyclases; Animals; Cardiotonic Agents; Carrier Proteins; Cell Line; Cell Line, Tumor; Chlor | 2007 |
Role of oxidative stress in hypertrophied myoblasts stimulated by isoproterenol.
Topics: Animals; Apoptosis; Cardiomegaly; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Gluco | 2008 |
Adrenergic beta receptors mediating submandibular salivary gland hypertrophy in the rat.
Topics: Adrenergic beta-Agonists; Animals; Cardiomegaly; Dose-Response Relationship, Drug; Hypertrophy; Isop | 1981 |
Adrenergic regulation of fat-cell lipolysis in multiple symmetric lipomatosis.
Topics: Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Dose-Response Relationship, Dru | 1982 |
The effect of short-term obstruction on urinary bladder function in the rabbit.
Topics: Adenosine Triphosphate; Animals; Bethanechol; Bethanechol Compounds; Electric Stimulation; Epinephri | 1984 |
Terbutaline-induced enlargement of the rat parotid gland.
Topics: Amylases; Animals; Female; Hypertrophy; Isoproterenol; Parotid Gland; Rats; Terbutaline | 1980 |
Increased beta-adrenergic receptor complement in androgen-induced mouse kidney hypertrophy.
Topics: Animals; Female; Hypertrophy; Isoproterenol; Kidney; Mice; Organ Size; Pindolol; Receptors, Adrenerg | 1981 |
Protein synthesis, amino acid uptake, and pools during isoproterenol-induced hypertrophy of the rat heart and tibialis muscle.
Topics: Amino Acids; Animals; Cardiomegaly; Hypertrophy; Isoproterenol; Male; Muscular Diseases; Protein Bio | 1981 |
Isoprenaline-induced changes in rat parotid and submandibular glands are age- and dosage-dependent.
Topics: Age Factors; Animals; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glycopr | 1984 |
Changes in rat parotid salivary proteins associated with liquid diet-induced gland atrophy and isoproterenol-induced gland enlargement.
Topics: Amino Acids; Animals; Atrophy; Chromatography, Ion Exchange; Diet; Electrophoresis, Polyacrylamide G | 1984 |
The secretion of protein and of some electrolytes in response to alpha- and beta- adrenergic agonists by rat parotid and submandibular salivary glands enlarged by chronic treatment with isoproterenol.
Topics: Electrolytes; Hypertrophy; Isoproterenol; Methoxamine; Parotid Gland; Salivary Proteins and Peptides | 1980 |
Isolated parotid acinar cells from DL-isoproterenol-treated rats. A cellular model for cystic fibrosis.
Topics: Animals; Cell Separation; Cell Survival; Cystic Fibrosis; Hypertrophy; Isoproterenol; Male; Models, | 1981 |
Regulation by isoproterenol of muscarinic acetylcholine receptor numbers and sensitivity in rat submandibular, but not lacrimal, glands.
Topics: Animals; Hyperplasia; Hypertrophy; Isoproterenol; Lacrimal Apparatus; Male; Organ Specificity; Rats; | 1982 |
Effects of chronic treatments upon the brown adipose tissue of rats. II. Comparison between the effects of catecholamine injections and cold adaptation.
Topics: Adaptation, Physiological; Adipose Tissue, Brown; Age Factors; Animals; Catecholamines; Cold Tempera | 1980 |
Hypertrophy and hyperplasia in the experimentally stimulated parotid gland.
Topics: Animals; Female; Hydroxyurea; Hyperplasia; Hypertrophy; Isoproterenol; Mice; Parotid Gland; Time Fac | 1981 |
Enlargement of salivary glands upon the combined effect of isoproterenol and of a cholesterol synthesis inhibitor (SC-12937).
Topics: Animals; Anticholesteremic Agents; Cholesterol; Female; Hypertrophy; Isoproterenol; Microscopy, Elec | 1980 |
Quantitative immunocytochemical study of secretory protein expression in parotid glands of rats chronically treated with isoproterenol.
Topics: Amylases; Animals; Cytoplasmic Granules; Hypertrophy; Immunohistochemistry; Injections, Intraperiton | 1995 |
Myosin heavy chain synthesis is independently regulated in hypertrophy and atrophy of isolated adult cardiac myocytes.
Topics: Actins; Animals; Atrophy; Calcium Channels; Cats; Cells, Cultured; Desmin; Gene Expression Regulatio | 1994 |
Alpha- and beta-adrenergic stimulation of protein synthesis in cultured adult ventricular cardiomyocytes.
Topics: Animals; Cells, Cultured; Creatine Kinase; Hypertrophy; Isoenzymes; Isoproterenol; Male; Muscle Prot | 1993 |
Loss of maximum attenuation and receptor reserve for isoprenaline at the beta 2-adrenoceptors of the portal veins of hypertensive rats.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alprenolol; Animals; Hypertension; Hypertroph | 1995 |
Angiotensin II release from rabbit intrarenal arteries: a critical assessment.
Topics: Adrenergic beta-Agonists; Angiotensin II; Animals; Arteries; Chromium Radioisotopes; Hypertension, R | 1997 |
Hepatocyte growth factor stimulates the differentiation of human tracheal epithelia in vitro.
Topics: Amiloride; Bradykinin; Cell Differentiation; Cell Division; Cell Membrane; Cells, Cultured; Chloride | 1997 |
Stereological study of acinar growth in the rat parotid gland induced by isoproterenol.
Topics: Animals; Cell Count; Cell Death; Cell Size; Hypertrophy; Isoproterenol; Male; Mitosis; Parotid Gland | 1997 |
Cell contact as an independent factor modulating cardiac myocyte hypertrophy and survival in long-term primary culture.
Topics: Adrenergic beta-Agonists; Animals; Cats; Cell Communication; Cell Count; Cell Culture Techniques; Ce | 1998 |
Effect of sympathetic innervation on isoproterenol-induced cystatin S gene expression in rat submandibular glands during early development.
Topics: Adrenergic beta-Agonists; Animals; Cystatins; Female; Ganglionectomy; Gene Expression Regulation; Hy | 1998 |
Changes in the expression of extracellular matrix (ECM) and matrix metalloproteinases (MMP) of proliferating rat parotid acinar cells.
Topics: Adrenergic beta-Agonists; Animals; Azo Compounds; Cell Division; Collagen; Coloring Agents; Dipeptid | 1998 |
Sphingosylphosphorylcholine induces a hypertrophic growth response through the mitogen-activated protein kinase signaling cascade in rat neonatal cardiac myocytes.
Topics: Adrenergic beta-Agonists; Animals; Animals, Newborn; Cell Size; Endothelin-1; Enzyme Inhibitors; Fla | 1999 |
Hypertrophic effect of selective beta(1)-adrenoceptor stimulation on ventricular cardiomyocytes from adult rat.
Topics: Adrenergic beta-Antagonists; Animals; Cardiomegaly; Cardiotonic Agents; Heart Ventricles; Hypertroph | 2000 |
Cell-enlargement-related polypeptides are induced via beta(1)-adrenoceptors in mouse parotids.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Atenolol; Cell Size; Dobu | 2000 |
Autonomic regulation of cystatin S gene expression in rat submandibular glands.
Topics: Animals; Autonomic Pathways; Cell Size; Cystatins; Female; Functional Laterality; Gene Expression Re | 2000 |
Involvement of angiotensin II and endothelin-1 in the development of submandibular gland hypertrophy in response to isoproterenol in rats.
Topics: Adrenergic beta-Agonists; Angiotensin II; Animals; Dobutamine; Enalapril; Endothelin-1; Hypertrophy; | 2000 |
Targeted disruption of the Nhe1 gene fails to inhibit beta(1)-adrenergic receptor-induced parotid gland hypertrophy.
Topics: Adrenergic beta-Agonists; Animals; Blotting, Northern; Cell Division; Hydrogen-Ion Concentration; Hy | 2001 |
Cardiac-specific LIM protein FHL2 modifies the hypertrophic response to beta-adrenergic stimulation.
Topics: Adrenergic beta-Agonists; Amino Acid Sequence; Animals; beta-Galactosidase; Blotting, Northern; Embr | 2001 |
Targeted overexpression of ornithine decarboxylase enhances beta-adrenergic agonist-induced cardiac hypertrophy.
Topics: Adrenergic beta-Agonists; Animals; Atenolol; Blotting, Southern; Cadaverine; Cardiomegaly; Hypertrop | 2001 |
Modification of mucus in animal models of disease.
Topics: Animals; Bronchi; Disease Models, Animal; Epithelium; Glycoproteins; Hydrogen-Ion Concentration; Hyp | 1977 |
[Echocardiographic diagnosis of obstructive myocardiopathies: study of the systolic anterior motion of the mitral valve and septal hypertrophy as compared with the hemodynamic and mechanographic findings. Evolution under medical treatment].
Topics: Adrenergic beta-Antagonists; Cardiomyopathy, Hypertrophic; Echocardiography; Heart Function Tests; H | 1979 |
Changes in taurine concentration in heart and skeletal muscle during atrophy and hypertrophy.
Topics: Amino Acids; Animals; Atrophy; Cardiomegaly; Hypertension; Hypertrophy; Isoproterenol; Male; Muscle | 1975 |
[Isoprenaline, propranolol and in vivo phosphorus metabolism of the rat salivary gland].
Topics: Animals; Hypertrophy; Isoproterenol; Male; Organ Size; Phosphates; Phosphatidylcholines; Phosphatidy | 1975 |
Beta-adrenergic receptors and adenylate cyclase in hypertrophic and hyperplastic rat salivary glands.
Topics: Adenylyl Cyclases; Alprenolol; Animals; Hyperplasia; Hypertrophy; In Vitro Techniques; Isoproterenol | 1978 |
Changes in protein secretion by rat submandibular salivary glands after enlargement caused by repeated amputation of the lower incisor teeth.
Topics: Animals; Body Weight; Hypertrophy; Incisor; Isoproterenol; Male; Methoxamine; Rats; Saliva; Salivary | 1979 |
Epidermal growth factor concentration in hyperplastic and hypertrophic submandibular salivary glands of mice.
Topics: Animals; Epidermal Growth Factor; Hyperplasia; Hypertrophy; Incisor; Isoproterenol; Mice; Peptides; | 1977 |
Sex difference in distribution and iron responsiveness of the two ferritins of rat cardiac and skeletal muscle.
Topics: Animals; Connective Tissue; Female; Ferritins; Hypertrophy; Iron; Isoproterenol; Male; Muscles; Myoc | 1977 |
[Effects of the oligo-mineral-chloride-bicarbonate-alkaline-sulphureous "S. Rocco di Tolentino" water on salivary glands hypertrophy induced in the rat by isoproterenol (author's transl)].
Topics: Animals; Bicarbonates; Chlorides; Hypertrophy; Isoproterenol; Italy; Male; Mineral Waters; Minerals; | 1977 |
Secretory behaviour of hypertrophic and hyperplastic salivary gland.
Topics: Amylases; Animals; Chloromercuribenzoates; Deoxyribonucleases; Female; Hyperplasia; Hypertrophy; Iso | 1977 |
The development and persistence of bronchialgland hypertrophy and goblet-cell hyperplasia in the pig after injection of isoprenaline.
Topics: Animals; Bronchi; Bronchial Diseases; Epithelium; Female; Hyperplasia; Hypertrophy; Isoproterenol; M | 1976 |
Molecular basis of a control mechanism of DNA synthesis in mammalian cells.
Topics: Animals; Cell Division; Cells, Cultured; DNA; Hypertrophy; In Vitro Techniques; Isoproterenol; Mice; | 1976 |
Stimulated growth of submandibular gland.
Topics: Animals; Body Weight; DNA; Female; Hyperplasia; Hypertrophy; Isoproterenol; Rats; Submandibular Glan | 1976 |
Immunofluorescence localization of cystatins in human lacrimal gland and in the exorbital lacrimal gland of the rat.
Topics: Animals; Carbachol; Cystatins; Fluorescent Antibody Technique; Hypertrophy; Isoproterenol; Lacrimal | 1992 |
A novel mechanism for isoprenaline-stimulated proliferation of rat parotid acinar cells involving the epidermal growth factor receptor and cell surface galactosyltransferase.
Topics: Animals; Antibodies; Antibodies, Monoclonal; Cell Division; Cell Line; Cell Membrane; DNA Replicatio | 1992 |
Regulation of cell-surface galactosyltransferase in isoproterenol-treated mouse parotid glands.
Topics: Animals; Cell Division; Cell Membrane; DNA; Female; Fluorescent Antibody Technique; Hypertrophy; Iso | 1991 |
Effect of nitrendipine, a calcium antagonist, on cell volume in rat salivary glands after isoproterenol stimulation.
Topics: Animals; Female; Hypertrophy; Isoproterenol; Microscopy; Nitrendipine; Organ Size; Rats; Salivary Gl | 1991 |
Effects of isoproterenol on I131 uptake by the submaxillary glands in mice.
Topics: Animals; Hypertrophy; Iodine Radioisotopes; Isoproterenol; Male; Mice; Submandibular Gland; Sympathe | 1990 |
Cooperative action of insulin and catecholamines on stimulation of ornithine decarboxylase activity in neonatal rat heart cells.
Topics: Animals; Blood Proteins; Calcimycin; Cardiomegaly; Catecholamines; Cells, Cultured; Cyclic AMP; Drug | 1990 |
Mitosis and hypertrophy of intercalated duct cells and endothelial cells in the isoproterenol-treated rat parotid gland.
Topics: Animals; Capillaries; Cell Differentiation; Cytoplasm; Cytoplasmic Granules; Endothelium; Hypertroph | 1985 |
Hypertrophy and dysfunction of parotid gland induced by chronic stimulation of beta 1-adrenergic receptors.
Topics: Adrenergic beta-Agonists; Amylases; Animals; Cardiomegaly; Cyclic AMP; Dobutamine; Hypertrophy; Isop | 1985 |
Alpha-lactalbumin acts as a bimodal regulator of rat parotid acinar cell growth.
Topics: Age Factors; Amylases; Animals; Animals, Newborn; beta-N-Acetylglucosaminylglycopeptide beta-1,4-Gal | 1987 |
The effects of upper incisor separation on the submandibular and sublingual glands of rats.
Topics: Animals; Autonomic Agents; Autonomic Nervous System; DNA; Hyperplasia; Hypertrophy; Incisor; Isoprot | 1988 |
Restoration of alpha-lactalbumin-inhibited rat parotid salivary gland hypertrophy and hyperplasia by agents specific for membrane glycoprotein N-acetylglucosamine.
Topics: Acetylglucosamine; Animals; Cell Division; Galactosyltransferases; Glucosamine; Hyperplasia; Hypertr | 1989 |
Pharmacological responses of rabbit urinary bladder after subtotal cystectomy.
Topics: Adenosine Triphosphate; Animals; Bethanechol; Bethanechol Compounds; Electric Stimulation; Epinephri | 1989 |
Isoproterenol-mediated parotid gland hypertrophy is inhibited by effectors of 4 beta-galactosyltransferase.
Topics: Animals; Cells, Cultured; Chromatography, High Pressure Liquid; DNA Replication; Enzyme Activation; | 1987 |
Alteration of membrane phospholipids in hypertrophied rat salivary glands induced by chronic administration of isoproterenol.
Topics: Animals; Fatty Acids; Hypertrophy; Isoproterenol; Male; Membrane Lipids; Organ Size; Parotid Gland; | 1987 |
Highly active Na+, K+-ATPase in rat submaxillary gland bearing on salivary secretion.
Topics: Adenosine Triphosphatases; Animals; Bile Acids and Salts; Biological Transport, Active; Chloromercur | 1968 |
The growth of the muscular and collagenous parts of the rat heart in various forms of cardiomegaly.
Topics: Anemia, Hypochromic; Animals; Cardiomegaly; Collagen; Hydroxyproline; Hypertension; Hypertrophy; Hyp | 1969 |
Effects of isoproterenol on the glycosaminglycans in salivary glands of the rat.
Topics: Animals; Chromatography; Glycosaminoglycans; Hyaluronic Acid; Hypertrophy; Isoproterenol; Male; Paro | 1970 |
[Cardiac hypertrophy induced by isoproterenol (morphometric, electron-microscopic, autoradiographic, cytophotometric and biochemical findings)].
Topics: Animals; Autoradiography; Cardiomegaly; Cell Nucleus; Chromatin; DNA; Edema; Glycogen; Histocytochem | 1972 |
Enlargement of salivary glands in rats after chronic administration of physalaemin or isoprenaline.
Topics: Animals; Female; Hyperplasia; Hypertrophy; Isoproterenol; Parotid Gland; Peptides; Rats; Salivary Gl | 1966 |
Effects of thyroid status and adrenergic blocking drugs on isoproterenol-induced enlargement of the salivary glands.
Topics: Animals; Hypertrophy; Hypothyroidism; Isoproterenol; Organ Size; Phenoxybenzamine; Propranolol; Rats | 1967 |
Factors influencing the production of cardiomyopathies by methoxamine and metaraminol.
Topics: Adrenalectomy; Adrenergic beta-Antagonists; Animals; Aortic Aneurysm; Blood Pressure; Diet; Edema; F | 1969 |
Selective metabolic and cardiovascular beta receptor antagonism in the rat.
Topics: Acetanilides; Adrenergic beta-Antagonists; Amino Alcohols; Animals; Blood Glucose; Blood Pressure; B | 1972 |
A quantitative morphological study of the effect of urethane on the stimulation of salivary gland growth by isoproterenol in the rat.
Topics: Animals; Cell Nucleus; Factor Analysis, Statistical; Hypertrophy; Isoproterenol; Male; Organ Size; P | 1972 |
Stimulation of DNA synthesis by isoproterenol in rat submandibular gland during postnatal growth.
Topics: Animals; Animals, Newborn; DNA; Female; Hyperplasia; Hypertrophy; Injections, Intraperitoneal; Injec | 1973 |
The effect of isoproterenol on the postnatal differentiation and growth of the rat submandibular gland.
Topics: Age Factors; Animals; Cell Differentiation; DNA; Epithelial Cells; Female; Hyperplasia; Hypertrophy; | 1973 |
Protein patterns in normal and induced pathological salivary glands of mice.
Topics: Animals; Benz(a)Anthracenes; Blood Proteins; Chromatography, Gel; Cytoplasm; Electrophoresis, Disc; | 1974 |
Turnover of ribosomal RNA in the submandibular gland of normal and isoproterenol-treated rats.
Topics: Animals; Carbon Isotopes; Centrifugation, Density Gradient; Cytidine; DNA; Female; Half-Life; Hyperp | 1972 |
Amylase changes accompanying stimulated salivary gland growth.
Topics: Amylases; Animals; Body Weight; Female; Hypertrophy; Isoproterenol; Male; Organ Size; Pancreatin; Ra | 1971 |
Study on the idiopathic cardiomyopathy. Diagnostic value of the apexcardiogram, 131 Cs scintiscanning of the heart and plasma hydroxyproline.
Topics: Adult; Amyl Nitrite; Autopsy; Cardiomyopathies; Cesium Isotopes; Child; Collagen; Collagen Diseases; | 1971 |
Effect of x-radiation on salivary gland growth in the rat. II. Quantitative studies of sialadenotrophism induced with isopropylnoradrenaline and its modification by single doses of x-rays.
Topics: Animals; Autoradiography; Body Weight; DNA; Heart; Hyperplasia; Hypertrophy; Isoproterenol; Mitosis; | 1970 |
Adrenergic mechanism responsible for submandibular salivary glandular hypertrophy in the rat.
Topics: Amino Acids; Aminophylline; Anilides; Animals; Body Weight; Carbon Isotopes; Epinephrine; Female; Gu | 1970 |
Cardiovascular responses to intravenous isoproterenol infusion in subjects with and without left ventricular hypertrophy.
Topics: Blood Pressure; Cardiac Output; Heart; Heart Diseases; Heart Rate; Heart Ventricles; Humans; Hypertr | 1970 |
Myocardial hypertrophy resulting from low dosage isoproterenol administration in rats.
Topics: Animals; Body Weight; Heart Diseases; Heart Rate; Hypertrophy; Isoproterenol; Organ Size; Rats; Tach | 1971 |
Effects of the optical isomers of isoproterenol upon salivary glands in rats.
Topics: Animals; Hypertrophy; Isoproterenol; Male; Organ Size; Rats; Salivary Glands; Stereoisomerism | 1967 |
Stimulation of protein and ribonucleic acid synthesis in rat submaxillary gland by isoproterenol.
Topics: Amino Acids; Animals; Carbon Isotopes; Cell Division; DNA; Fasting; Female; Hyperplasia; Hypertrophy | 1968 |
The effect of isoproterenol on peptide hydrolase activities of submandibular gland.
Topics: Animals; Hypertrophy; Isoproterenol; Mice; Peptide Hydrolases; Rats; Sex Factors; Submandibular Glan | 1969 |
Modification of irradiation effects on rat parotid by chronic pretreatment with isoproterenol.
Topics: Animals; Diploidy; Female; Hypertrophy; Isoproterenol; Mitosis; Organ Size; Parotid Gland; Polyploid | 1969 |
Primary pulmonary hypertension in a child. Response to pharmacologic agents.
Topics: Acetylcholine; Blood Pressure; Cardiac Catheterization; Cardiac Output; Child; Heart Ventricles; Hex | 1969 |
Membrane potentials of salivary gland cells of rat.
Topics: Animals; Electrophysiology; Hypertrophy; Isoproterenol; Parotid Gland; Pilocarpine; Rats; Salivary G | 1965 |