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isoproterenol and Hypertension, Portal

isoproterenol has been researched along with Hypertension, Portal in 12 studies

Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.

Hypertension, Portal: Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN.

Research Excerpts

ExcerptRelevanceReference
"Propranolol is a widely used drug for prophylaxis of variceal bleeding in patients with cirrhosis, but not all patients show an adequate clinical response."2.72Functional status of beta-2-adrenoceptor in isolated membranes of mature erythrocytes from patients with cirrhosis and oesophageal varices. ( De-Madaria, E; Hernández, FT; Horga, JF; Irurzun, J; Palazón, JM; Pascual, S; Perez-Mateo, M; Such, J; Zapater, P, 2006)
"The animals developed oesophageal varices and these together with the small mesenteric veins were mounted on a myograph."1.27Mechanical, morphological and pharmacological properties of oesophageal varices and small mesenteric veins in portal hypertensive rabbits. ( Jensen, LS; Juhl, CO; Mulvany, MJ, 1987)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19907 (58.33)18.7374
1990's3 (25.00)18.2507
2000's2 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
KALAS, JP1
JACOBSON, ED1
Hernández, FT1
Zapater, P1
De-Madaria, E1
Palazón, JM1
Pascual, S1
Irurzun, J1
Such, J1
Perez-Mateo, M1
Horga, JF1
Weinshel, EH1
Altszuler, HM1
Raicht, RF1
Sedlis, SP1
Bomzon, A1
Binah, O1
Blendis, LM1
Zavecz, JH1
Bueno, O1
Maloney, RE1
O'Donnell, JM1
Roerig, SC1
Battarbee, HD1
Lee, SS2
Marty, J1
Mantz, J1
Samain, E1
Braillon, A2
Lebrec, D2
Kaumann, AJ1
Groszmann, RJ1
Girod, C1
Geoffroy, P1
Jensen, LS1
Juhl, CO1
Mulvany, MJ1
Sirinek, KR2
Thomford, NR2
White, JJ1

Trials

1 trial available for isoproterenol and Hypertension, Portal

ArticleYear
Functional status of beta-2-adrenoceptor in isolated membranes of mature erythrocytes from patients with cirrhosis and oesophageal varices.
    Vascular pharmacology, 2006, Volume: 44, Issue:6

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alcohol Drinking; Cyclic A

2006

Other Studies

11 other studies available for isoproterenol and Hypertension, Portal

ArticleYear
THE EFFECT OF VASOACTIVE ANTAGONISTS IN ENDOTOXIN SHOCK.
    American heart journal, 1964, Volume: 67

    Topics: Animals; Atropine; Blood Circulation; Blood Pressure; Blood Pressure Determination; Chloralose; Cypr

1964
Beta adrenergic stimulation and blockade in cirrhosis: effects on azygos vein blood flow and portal hemodynamics.
    The American journal of the medical sciences, 1994, Volume: 307, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Azygos Vein; Hemodynamics; Humans; Hypertension, Portal; I

1994
Hypotension in experimental cirrhosis. Is loss of vascular responsiveness to norepinephrine the cause of hypotension in chronic bile-duct-ligated dogs?
    Journal of hepatology, 1993, Volume: 17, Issue:1

    Topics: Aldosterone; Animals; Arteries; Atrial Natriuretic Factor; Bile Ducts; Bilirubin; Blood Pressure; Do

1993
Cardiac excitation-contraction coupling in the portal hypertensive rat.
    American journal of physiology. Gastrointestinal and liver physiology, 2000, Volume: 279, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2000
Desensitization of myocardial beta-adrenergic receptors in cirrhotic rats.
    Hepatology (Baltimore, Md.), 1990, Volume: 12, Issue:3 Pt 1

    Topics: Animals; Disease Models, Animal; Down-Regulation; Heart; Heart Rate; Hypertension, Portal; Isoproter

1990
Catecholamines relax portal and mesenteric veins from normal and portal hypertensive rats.
    The American journal of physiology, 1989, Volume: 257, Issue:6 Pt 1

    Topics: Adrenergic beta-Antagonists; Animals; Buserelin; Epinephrine; Goserelin; Hypertension, Portal; Imida

1989
Haemodynamic rebound phenomena after abrupt cessation of propranolol therapy in portal hypertensive rats.
    Journal of hepatology, 1986, Volume: 3, Issue:1

    Topics: Animals; Depression, Chemical; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Hypertens

1986
Mechanical, morphological and pharmacological properties of oesophageal varices and small mesenteric veins in portal hypertensive rabbits.
    Acta physiologica Scandinavica, 1987, Volume: 130, Issue:4

    Topics: Angiotensin II; Animals; Esophageal and Gastric Varices; Hypertension, Portal; Isoproterenol; Mesent

1987
The effect of vasopressin on portal hypertension following hepatectomy.
    Surgery, gynecology & obstetrics, 1974, Volume: 139, Issue:4

    Topics: Animals; Blood Pressure; Cardiac Output; Dogs; Drug Synergism; Drug Therapy, Combination; Hepatectom

1974
Pharmacologic control of posthepatectomy portal hypertension.
    Surgical forum, 1973, Volume: 24

    Topics: Animals; Cardiac Output; Dogs; Hepatectomy; Hypertension, Portal; Isoproterenol; Vasopressins

1973
Direct portal hepatography and metabolic studies via the reopened umbilical vein. Effect of vasoactive drugs on portal pressure, blood gases and lactates.
    The American surgeon, 1968, Volume: 34, Issue:12

    Topics: Blood Pressure Determination; Carbon Dioxide; Female; Hemodynamics; Humans; Hypertension, Portal; Is

1968