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isoproterenol and Hyperplasia

isoproterenol has been researched along with Hyperplasia in 41 studies

Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.

Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.

Research Excerpts

ExcerptRelevanceReference
"Chronic isoproterenol treatment of rats results in hypertrophy and hyperplasia of the parotid gland."7.67Restoration of alpha-lactalbumin-inhibited rat parotid salivary gland hypertrophy and hyperplasia by agents specific for membrane glycoprotein N-acetylglucosamine. ( Humphreys-Beher, MG, 1989)
"T-cell phenotype that regulates isoproterenol-induced lymphocyte-dependent hyperplasia of mouse salivary glands and conditions of its activation has been investigated."7.67[Isoproterenol-induced, lymphocyte-dependent hyperplasia of mouse salivary glands--a possible analog of a syngeneic mixed lymphocyte culture in vivo]. ( Dontsov, VI, 1987)
"Chronic isoproterenol treatment causes hypertrophy and hyperplasia of rodent salivary glands."3.79Isoproterenol modulates matrix metalloproteinase-2 (MMP-2) and its tissue inhibitor-2 (TIMP-2) in rat parotid gland. ( D'Amico, F; Malaponte, G; Mangano, K; Mazzarino, MC; Skarmoutsou, E, 2013)
" Chronic injections of the beta-adrenergic receptor agonist, isoproterenol, result in a non-neoplastic hypertrophy and hyperplasia of the rat parotid gland."3.70Changes in the expression of extracellular matrix (ECM) and matrix metalloproteinases (MMP) of proliferating rat parotid acinar cells. ( Brinkley, LL; Broverman, RL; da Silveira, A; Humphreys-Beher, MG; Kerr, M; Macauley, SP; Nguyen, KH; Schultz, GS; Tarnuzzer, RW; Yamamoto, H; Zeng, T, 1998)
"Chronic injections of epidermal growth factor (EGF) or the beta-adrenergic receptor agonist isoprenaline resulted in rat parotid gland hypertrophy and hyperplasia."3.68A novel mechanism for isoprenaline-stimulated proliferation of rat parotid acinar cells involving the epidermal growth factor receptor and cell surface galactosyltransferase. ( Dunn, WA; Humphreys-Beher, MG; Purushotham, KR; Schneyer, CA, 1992)
"Chronic isoproterenol treatment of rats results in hypertrophy and hyperplasia of the parotid gland."3.67Restoration of alpha-lactalbumin-inhibited rat parotid salivary gland hypertrophy and hyperplasia by agents specific for membrane glycoprotein N-acetylglucosamine. ( Humphreys-Beher, MG, 1989)
"The study of the mechanisms leading to cardiac hypertrophy is essential to better understand cardiac development and regeneration."1.43Loss of Mouse P2Y6 Nucleotide Receptor Is Associated with Physiological Macrocardia and Amplified Pathological Cardiac Hypertrophy. ( Balligand, JL; Beauloye, C; Boeynaems, JM; Clouet, S; Communi, D; Daskalopoulos, EP; Di Pietrantonio, L; Esfahani, H; Horckmans, M; Lemaire, A; Vanorlé, M, 2016)
"Hdac3-Tg mice did not develop cardiac hypertrophy at 3 months of age, unlike previously reported Hdac2-Tg mice."1.35Transgenic overexpression of Hdac3 in the heart produces increased postnatal cardiac myocyte proliferation but does not induce hypertrophy. ( Epstein, JA; Lu, MM; Trivedi, CM; Wang, Q, 2008)
" In comparison with control animals, the enlarged submandibular glands of rats subjected to orthodontic treatment secreted additional proteins identical with those secreted by glands enlarged by chronic administration of isoproterenol."1.27The effects of upper incisor separation on the submandibular and sublingual glands of rats. ( Abe, K; Ichikawa, K; Ishibashi, K; Itoh, T; Kamogashira, K; Matsumoto, M; Yanabu, M, 1988)
"The enzyme content and the secretory behaviour of normal rat salivary glands were compared with these properties in glands made hypertrophic and hyperplastic by the chronic administration of isoproterenol."1.26Secretory behaviour of hypertrophic and hyperplastic salivary gland. ( Barka, T; Burke, GT, 1977)
"The hypertrophy was due to an increase in size of mucous cells, which were filled with secretion."1.26The development and persistence of bronchialgland hypertrophy and goblet-cell hyperplasia in the pig after injection of isoprenaline. ( Baskerville, A, 1976)
" Chronic administration of IPR led to an increase in the frequency of acinar cells."1.26Stimulated growth of submandibular gland. ( Barka, T; Van Der Noen, H, 1976)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199030 (73.17)18.7374
1990's5 (12.20)18.2507
2000's3 (7.32)29.6817
2010's3 (7.32)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kurt, B1
Karger, C1
Wagner, C1
Kurtz, A1
Clouet, S1
Di Pietrantonio, L1
Daskalopoulos, EP1
Esfahani, H1
Horckmans, M1
Vanorlé, M1
Lemaire, A1
Balligand, JL1
Beauloye, C1
Boeynaems, JM1
Communi, D1
Trivedi, CM1
Lu, MM1
Wang, Q1
Epstein, JA1
D'Amico, F1
Skarmoutsou, E1
Mangano, K1
Malaponte, G1
Mazzarino, MC1
Miyamura, N1
Taguchi, T1
Murata, Y1
Taketa, K1
Iwashita, S1
Matsumoto, K1
Nishikawa, T1
Toyonaga, T1
Sakakida, M1
Araki, E1
POHTO, P1
PAASONEN, MK1
CHAN, WC1
BARKA, T9
Klein, RM1
Carling, RC1
Templeton, D1
Hootman, SR1
Kiefer, G1
Kaupp, R1
Engler, H1
Chisholm, DM1
Adi, MM1
Abelenda, M1
Castro, C1
Venero, C1
Puerta, M1
Chaparro, O1
Yu, WH1
Shaw, PA1
Broverman, RL1
Nguyen, KH1
da Silveira, A1
Brinkley, LL1
Macauley, SP1
Zeng, T1
Yamamoto, H1
Tarnuzzer, RW1
Schultz, GS1
Kerr, M1
Humphreys-Beher, MG3
Heijenbrok, FJ1
Mathy, MJ1
Pfaffendorf, M1
van Zwieten, PA1
Taylor, PB1
Swanson, CT1
Draisey, TF1
Burke, GT2
Roberts, ML1
Baskerville, A1
Van Der Noen, H3
Purushotham, KR1
Dunn, WA1
Schneyer, CA2
Kamogashira, K1
Yanabu, M1
Ichikawa, K1
Itoh, T1
Matsumoto, M1
Ishibashi, K1
Abe, K1
Dontsov, VI2
Yagil, C1
Tomich, CE1
Eversole, LR1
Bertaccini, G1
De Caro, G1
Cheli, R1
Radley, JM1
Hodgson, GS1
Chang, WW2
Srinivasan, R1
Feiglin, B1
Reade, PC1
Hoshino, K1
Lin, CD1
Van den Brenk, HA1
Sparrow, N1
Moore, V1
Shklar, G1
Cataldo, E1

Other Studies

41 other studies available for isoproterenol and Hyperplasia

ArticleYear
Control of renin secretion from kidneys with renin cell hyperplasia.
    American journal of physiology. Renal physiology, 2014, Feb-01, Volume: 306, Issue:3

    Topics: Animals; Connexins; Cytochrome P-450 CYP11B2; Female; Gap Junction alpha-5 Protein; Hyperplasia; Iso

2014
Loss of Mouse P2Y6 Nucleotide Receptor Is Associated with Physiological Macrocardia and Amplified Pathological Cardiac Hypertrophy.
    The Journal of biological chemistry, 2016, 07-22, Volume: 291, Issue:30

    Topics: Animals; Cardiomegaly; Hyperplasia; Isoproterenol; Male; Mice; Mice, Knockout; Myocardial Ischemia;

2016
Transgenic overexpression of Hdac3 in the heart produces increased postnatal cardiac myocyte proliferation but does not induce hypertrophy.
    The Journal of biological chemistry, 2008, Sep-26, Volume: 283, Issue:39

    Topics: Animals; Animals, Newborn; Cardiomegaly; Cardiotonic Agents; Cell Proliferation; Cyclin-Dependent Ki

2008
Isoproterenol modulates matrix metalloproteinase-2 (MMP-2) and its tissue inhibitor-2 (TIMP-2) in rat parotid gland.
    Archives of oral biology, 2013, Volume: 58, Issue:4

    Topics: Adrenergic beta-Agonists; Animals; Cell Proliferation; Female; Hyperplasia; Hypertrophy; Immunohisto

2013
Inherited adrenocorticotropin-independent macronodular adrenal hyperplasia with abnormal cortisol secretion by vasopressin and catecholamines: detection of the aberrant hormone receptors on adrenal gland.
    Endocrine, 2002, Volume: 19, Issue:3

    Topics: Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Glands; Adrenergic beta-Agonists; Adrenocor

2002
STUDIES ON THE SALIVARY GLAND HYPERTROPHY INDUCED IN RATS BY ISOPRENALINE.
    Acta pharmacologica et toxicologica, 1964, Volume: 21

    Topics: Hyperplasia; Hypertrophy; Isoproterenol; Parotid Gland; Pharmacology; Rats; Research; Salivary Gland

1964
ENLARGEMENT OF THE RAT'S SALIVARY GLANDS AND SALIVARY CALCULUS FORMATION INDUCED WITH ISOPRENALINE.
    The Journal of pathology and bacteriology, 1964, Volume: 88

    Topics: Calcinosis; Hyperplasia; Hypertrophy; Isoproterenol; Rats; Research; Salivary Calculi; Salivary Glan

1964
INDUCED CELL PROLIFERATION: THE EFFECT OF ISOPROTERENOL.
    Experimental cell research, 1965, Volume: 37

    Topics: Autoradiography; Cell Division; Cell Proliferation; DNA; Hyperplasia; Hypertrophy; Isoproterenol; Ki

1965
Beta-adrenergic drug induced hyperplasia in the immature rat parotid and submandibular glands.
    European journal of pharmacology, 1984, Oct-15, Volume: 105, Issue:3-4

    Topics: Adrenergic beta-Agonists; Animals; Cell Division; Female; Hyperplasia; Isoproterenol; Organ Size; Pa

1984
The effect of carbachol and isoprenaline on cell division in the exocrine pancreas of the rat.
    Quarterly journal of experimental physiology (Cambridge, England), 1982, Volume: 67, Issue:4

    Topics: Amylases; Animals; Carbachol; Cell Division; DNA; Hyperplasia; Isoproterenol; Male; Pancreas; Rats;

1982
Regulation by isoproterenol of muscarinic acetylcholine receptor numbers and sensitivity in rat submandibular, but not lacrimal, glands.
    Biochimica et biophysica acta, 1982, Jun-16, Volume: 716, Issue:3

    Topics: Animals; Hyperplasia; Hypertrophy; Isoproterenol; Lacrimal Apparatus; Male; Organ Specificity; Rats;

1982
Hypertrophy and hyperplasia in the experimentally stimulated parotid gland.
    Pathology, research and practice, 1981, Volume: 173, Issue:1-2

    Topics: Animals; Female; Hydroxyurea; Hyperplasia; Hypertrophy; Isoproterenol; Mice; Parotid Gland; Time Fac

1981
Cell proliferation and apoptosis in isoprenaline-induced sialosis in the rat submandibular glands.
    International journal of experimental pathology, 1995, Volume: 76, Issue:4

    Topics: Animals; Apoptosis; Cell Division; Cell Nucleus; Cytoplasm; Hyperplasia; Isoproterenol; Male; Mitoti

1995
Reduced oxygen consumption of brown adipocytes isolated from progesterone-treated rats.
    Canadian journal of physiology and pharmacology, 1994, Volume: 72, Issue:10

    Topics: Adipocytes; Adipose Tissue, Brown; Animals; Dose-Response Relationship, Drug; Electron Transport Com

1994
Effect of sympathetic innervation on isoproterenol-induced cystatin S gene expression in rat submandibular glands during early development.
    Developmental neuroscience, 1998, Volume: 20, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Cystatins; Female; Ganglionectomy; Gene Expression Regulation; Hy

1998
Changes in the expression of extracellular matrix (ECM) and matrix metalloproteinases (MMP) of proliferating rat parotid acinar cells.
    Journal of dental research, 1998, Volume: 77, Issue:7

    Topics: Adrenergic beta-Agonists; Animals; Azo Compounds; Cell Division; Collagen; Coloring Agents; Dipeptid

1998
Beta-adrenergic responses are significantly enhanced in rat carotid artery with intimal hyperplasia.
    Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 362, Issue:3

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carotid Artery Injuries; Dose-Respon

2000
Quantitative histological changes in isoproterenol induced cardiac growth.
    Research communications in chemical pathology and pharmacology, 1977, Volume: 17, Issue:2

    Topics: Animals; Body Weight; Cardiomegaly; Female; Heart; Hyperplasia; Isoproterenol; Myocardium; Organ Siz

1977
Beta-adrenergic receptors and adenylate cyclase in hypertrophic and hyperplastic rat salivary glands.
    Biochimica et biophysica acta, 1978, Feb-13, Volume: 539, Issue:1

    Topics: Adenylyl Cyclases; Alprenolol; Animals; Hyperplasia; Hypertrophy; In Vitro Techniques; Isoproterenol

1978
Epidermal growth factor concentration in hyperplastic and hypertrophic submandibular salivary glands of mice.
    Archives of oral biology, 1977, Volume: 22, Issue:4

    Topics: Animals; Epidermal Growth Factor; Hyperplasia; Hypertrophy; Incisor; Isoproterenol; Mice; Peptides;

1977
Secretory behaviour of hypertrophic and hyperplastic salivary gland.
    The Histochemical journal, 1977, Volume: 9, Issue:4

    Topics: Amylases; Animals; Chloromercuribenzoates; Deoxyribonucleases; Female; Hyperplasia; Hypertrophy; Iso

1977
The development and persistence of bronchialgland hypertrophy and goblet-cell hyperplasia in the pig after injection of isoprenaline.
    The Journal of pathology, 1976, Volume: 119, Issue:1

    Topics: Animals; Bronchi; Bronchial Diseases; Epithelium; Female; Hyperplasia; Hypertrophy; Isoproterenol; M

1976
Stimulated growth of submandibular gland.
    Laboratory investigation; a journal of technical methods and pathology, 1976, Volume: 35, Issue:5

    Topics: Animals; Body Weight; DNA; Female; Hyperplasia; Hypertrophy; Isoproterenol; Rats; Submandibular Glan

1976
A novel mechanism for isoprenaline-stimulated proliferation of rat parotid acinar cells involving the epidermal growth factor receptor and cell surface galactosyltransferase.
    The Biochemical journal, 1992, Jun-15, Volume: 284 ( Pt 3)

    Topics: Animals; Antibodies; Antibodies, Monoclonal; Cell Division; Cell Line; Cell Membrane; DNA Replicatio

1992
The effects of upper incisor separation on the submandibular and sublingual glands of rats.
    Journal of dental research, 1988, Volume: 67, Issue:3

    Topics: Animals; Autonomic Agents; Autonomic Nervous System; DNA; Hyperplasia; Hypertrophy; Incisor; Isoprot

1988
Restoration of alpha-lactalbumin-inhibited rat parotid salivary gland hypertrophy and hyperplasia by agents specific for membrane glycoprotein N-acetylglucosamine.
    Archives of oral biology, 1989, Volume: 34, Issue:10

    Topics: Acetylglucosamine; Animals; Cell Division; Galactosyltransferases; Glucosamine; Hyperplasia; Hypertr

1989
[Isoproterenol-induced, lymphocyte-dependent hyperplasia of mouse salivary glands--a possible analog of a syngeneic mixed lymphocyte culture in vivo].
    Biulleten' eksperimental'noi biologii i meditsiny, 1987, Volume: 104, Issue:11

    Topics: Animals; Female; Hyperplasia; Isoproterenol; Lymphocyte Culture Test, Mixed; Lymphocytes; Mice; Sali

1987
[Regulation of isoproterenol-induced salivary gland hyperplasia in young and old mice by substances affecting the serotonin- and dopaminergic systems].
    Biulleten' eksperimental'noi biologii i meditsiny, 1986, Volume: 101, Issue:4

    Topics: Aging; Animals; Female; Freund's Adjuvant; Hyperplasia; Isoproterenol; Levodopa; Mice; Mice, Inbred

1986
Induction of a specific (LM) protein in the submandibular gland of the rat by repeated amputation of the lower incisor teeth.
    The American journal of anatomy, 1986, Volume: 177, Issue:4

    Topics: Animals; Female; Histocytochemistry; Hyperplasia; Incisor; Isoproterenol; Rats; Rats, Inbred Strains

1986
The enzyme histochemistry of isoproterenol-induced salivary gland hyperplasia.
    Oral surgery, oral medicine, and oral pathology, 1972, Volume: 33, Issue:5

    Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Electron Transport Complex IV; Glucosephosphate Deh

1972
Enlargement of salivary glands in rats after chronic administration of physalaemin or isoprenaline.
    The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:5

    Topics: Animals; Female; Hyperplasia; Hypertrophy; Isoproterenol; Parotid Gland; Peptides; Rats; Salivary Gl

1966
Effect of isoprenaline on cells in different phases of the mitotic cycle.
    Experimental cell research, 1971, Volume: 69, Issue:1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Autoradiography; Cell Nucleus; Cells

1971
Stimulation of DNA synthesis by isoproterenol in rat submandibular gland during postnatal growth.
    Cell and tissue kinetics, 1973, Volume: 6, Issue:2

    Topics: Animals; Animals, Newborn; DNA; Female; Hyperplasia; Hypertrophy; Injections, Intraperitoneal; Injec

1973
A growth-suppressive influence of L-isoproterenol on postnatally developing parotid gland of rat.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1973, Volume: 143, Issue:4

    Topics: Age Factors; Animals; Cell Differentiation; DNA; Female; Hyperplasia; Isoproterenol; Male; Mitosis;

1973
The effect of isoproterenol on the postnatal differentiation and growth of the rat submandibular gland.
    The Anatomical record, 1973, Volume: 177, Issue:2

    Topics: Age Factors; Animals; Cell Differentiation; DNA; Epithelial Cells; Female; Hyperplasia; Hypertrophy;

1973
Protein patterns in normal and induced pathological salivary glands of mice.
    The Australian journal of experimental biology and medical science, 1974, Volume: 52, Issue:1

    Topics: Animals; Benz(a)Anthracenes; Blood Proteins; Chromatography, Gel; Cytoplasm; Electrophoresis, Disc;

1974
Turnover of ribosomal RNA in the submandibular gland of normal and isoproterenol-treated rats.
    Experimental cell research, 1972, Volume: 74, Issue:2

    Topics: Animals; Carbon Isotopes; Centrifugation, Density Gradient; Cytidine; DNA; Female; Half-Life; Hyperp

1972
Induction of hyperplasia in mouse salivary gland isografts.
    European journal of cancer, 1971, Volume: 7, Issue:5

    Topics: Animals; Cell Differentiation; Estradiol; Female; Hyperplasia; Isoproterenol; Mitosis; Rats; Salivar

1971
Effect of x-radiation on salivary gland growth in the rat. II. Quantitative studies of sialadenotrophism induced with isopropylnoradrenaline and its modification by single doses of x-rays.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1970, Volume: 17, Issue:2

    Topics: Animals; Autoradiography; Body Weight; DNA; Heart; Hyperplasia; Hypertrophy; Isoproterenol; Mitosis;

1970
Stimulation of protein and ribonucleic acid synthesis in rat submaxillary gland by isoproterenol.
    Laboratory investigation; a journal of technical methods and pathology, 1968, Volume: 18, Issue:1

    Topics: Amino Acids; Animals; Carbon Isotopes; Cell Division; DNA; Fasting; Female; Hyperplasia; Hypertrophy

1968
Effects of a chemical carcinogen on the submaxillary gland of albino rats treated with isoproterenol.
    Cancer research, 1966, Volume: 26, Issue:7

    Topics: Animals; Benz(a)Anthracenes; Hyperplasia; Isoproterenol; Neoplasms, Experimental; Rats; Submandibula

1966