isoproterenol has been researched along with Hyperinsulinism in 14 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Hyperinsulinism: A syndrome with excessively high INSULIN levels in the BLOOD. It may cause HYPOGLYCEMIA. Etiology of hyperinsulinism varies, including hypersecretion of a beta cell tumor (INSULINOMA); autoantibodies against insulin (INSULIN ANTIBODIES); defective insulin receptor (INSULIN RESISTANCE); or overuse of exogenous insulin or HYPOGLYCEMIC AGENTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hyperinsulinemia in obesity has been attributed to insulin oversecretion by pancreatic beta-cells." | 1.33 | The dual effect of isoproterenol on insulin release is suppressed in pancreatic islets from hypothalamic obese rats. ( da Rocha, DN; de Freitas Mathias, PC; Grassiolli, S; Gravena, C; Marçal, AC; Puzzi, MA; Scomparin, DX, 2006) |
| "The effect of dietary olive oil and fish oil on the lipolytic dose-response of the beta3-adrenergic agonists, epinephrine, isoproterenol, BRL-37344, and CGP-12177, in adipocytes was studied in pregnant and virgin rats either untreated or under hyperinsulinemic-euglycemic conditions." | 1.31 | Changes in dietary fatty acids modify the decreased lipolytic beta3-adrenergic response to hyperinsulinemia in adipocytes from pregnant and nonpregnant rats. ( Amusquivar, E; Cacho, J; Herrera, E, 2000) |
| "In such a condition, hyperinsulinemia could be due to an increased lipolytic activity of omental adipose tissue (AT), through an enhanced portal flux of FFA." | 1.29 | Omental and epigastric adipose tissue lipolytic activity in human obesity. Effect of abdominal fat distribution and relationship with hyperinsulinemia. ( Busetto, L; Carraro, R; Dalla Montá, P; Digito, M; Enzi, G, 1993) |
| "Risk factors for NIDDM were estimated by proportional-hazards analysis and risk ratios (RR) with 95% confidence intervals (95% CI) calculated at the 90th and 10th percentile of the predictor variables." | 1.29 | A high concentration of fasting plasma non-esterified fatty acids is a risk factor for the development of NIDDM. ( Bogardus, C; Foley, JE; Howard, BV; Paolisso, G; Ravussin, E; Tataranni, PA, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (21.43) | 18.7374 |
| 1990's | 4 (28.57) | 18.2507 |
| 2000's | 6 (42.86) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Higa, TS | 1 |
| Spinola, AV | 1 |
| Fonseca-Alaniz, MH | 1 |
| Evangelista, FS | 1 |
| Stich, V | 1 |
| Pelikanova, T | 1 |
| Wohl, P | 1 |
| Sengenès, C | 1 |
| Zakaroff-Girard, A | 1 |
| Lafontan, M | 1 |
| Berlan, M | 1 |
| Marçal, AC | 1 |
| Grassiolli, S | 1 |
| da Rocha, DN | 1 |
| Puzzi, MA | 1 |
| Gravena, C | 1 |
| Scomparin, DX | 1 |
| de Freitas Mathias, PC | 1 |
| Beard, JC | 1 |
| Halter, JB | 1 |
| Best, JD | 1 |
| Pfeifer, MA | 1 |
| Porte, D | 1 |
| Inoue, S | 1 |
| Mullen, YS | 1 |
| Bray, GA | 1 |
| Busetto, L | 1 |
| Digito, M | 1 |
| Dalla Montá, P | 1 |
| Carraro, R | 1 |
| Enzi, G | 1 |
| Paolisso, G | 1 |
| Tataranni, PA | 1 |
| Foley, JE | 1 |
| Bogardus, C | 1 |
| Howard, BV | 1 |
| Ravussin, E | 1 |
| Tack, CJ | 1 |
| Smits, P | 1 |
| O'Callaghan, CJ | 1 |
| Komersova, K | 1 |
| Louis, WJ | 1 |
| Doaré, L | 1 |
| Mesangeau, D | 1 |
| Adli, H | 1 |
| Germack, R | 1 |
| Perret, G | 1 |
| Valensi, P | 1 |
| Herrera, E | 1 |
| Amusquivar, E | 1 |
| Cacho, J | 1 |
| Huisamen, B | 1 |
| Marais, E | 1 |
| Genade, S | 1 |
| Lochner, A | 1 |
| Karpe, F | 1 |
| Fielding, BA | 1 |
| Ardilouze, JL | 1 |
| Ilic, V | 1 |
| Macdonald, IA | 1 |
| Frayn, KN | 1 |
| Hepp, KD | 1 |
1 review available for isoproterenol and Hyperinsulinism
| Article | Year |
|---|---|
Studies on the mechanism of insulin action: basic concepts and clinical implications.
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Calcium; Cell Membrane; Cyc | 1977 |
2 trials available for isoproterenol and Hyperinsulinism
| Article | Year |
|---|---|
Activation of alpha2-adrenergic receptors blunts epinephrine-induced lipolysis in subcutaneous adipose tissue during a hyperinsulinemic euglycemic clamp in men.
Topics: Adipose Tissue; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adult; Epinephrine; Glucose | 2003 |
Acute effects of blood pressure elevation on insulin clearance in normotensive healthy subjects.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adult; Angiotensin II; Blood Glucose; Blood Pre | 1998 |
11 other studies available for isoproterenol and Hyperinsulinism
| Article | Year |
|---|---|
Remodeling of white adipose tissue metabolism by physical training prevents insulin resistance.
Topics: Adipocytes; Adiponectin; Adipose Tissue, White; Adiposity; Animals; Fatty Acids, Nonesterified; Gluc | 2014 |
The dual effect of isoproterenol on insulin release is suppressed in pancreatic islets from hypothalamic obese rats.
Topics: Animals; Animals, Newborn; Blood Glucose; Hyperinsulinism; In Vitro Techniques; Insulin; Insulin Sec | 2006 |
Dexamethasone-induced insulin resistance enhances B cell responsiveness to glucose level in normal men.
Topics: Adaptation, Physiological; Adult; Blood Glucose; Dexamethasone; Humans; Hyperglycemia; Hyperinsulini | 1984 |
Hyperinsulinemia in rats with hypothalamic obesity: effects of autonomic drugs and glucose.
Topics: Animals; Atropine; Epinephrine; Female; Glucose; Hyperinsulinism; Isoproterenol; Obesity; Phentolami | 1983 |
Omental and epigastric adipose tissue lipolytic activity in human obesity. Effect of abdominal fat distribution and relationship with hyperinsulinemia.
Topics: Abdomen; Adipose Tissue; Adult; Catecholamines; Female; Gastric Mucosa; Glucose; Glucose Tolerance T | 1993 |
A high concentration of fasting plasma non-esterified fatty acids is a risk factor for the development of NIDDM.
Topics: Adipocytes; Adipose Tissue; Adult; Arizona; Biomarkers; Blood Glucose; Cells, Cultured; Confidence I | 1995 |
Regional hyperinsulinemia does not modulate beta-adrenergic vasodilator action.
Topics: Adrenergic beta-Agonists; Forearm; Humans; Hyperinsulinism; Insulin; Isoproterenol; Receptors, Adren | 1997 |
[Hemodynamic consequences of endogenous hyperinsulinism in obese rats with lesions of the ventromedial hypothalamus].
Topics: Adrenergic Agonists; Adrenergic beta-Agonists; Animals; Atropine; Baroreflex; Blood Pressure; Bradyc | 2000 |
Changes in dietary fatty acids modify the decreased lipolytic beta3-adrenergic response to hyperinsulinemia in adipocytes from pregnant and nonpregnant rats.
Topics: Adipocytes; Adrenergic beta-Agonists; Animals; Dietary Fats; Epinephrine; Ethanolamines; Fatty Acids | 2000 |
Serial changes in the myocardial beta-adrenergic signalling system in two models of non-insulin dependent diabetes mellitus.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Age Factors; Aminoglycosides; Animals; Animals, Newborn | 2001 |
Effects of insulin on adipose tissue blood flow in man.
Topics: Adipose Tissue; Administration, Oral; Blood Glucose; Fatty Acids, Nonesterified; Glucose; Glucose Cl | 2002 |