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isoproterenol and Hyperemia

isoproterenol has been researched along with Hyperemia in 29 studies

Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.

Hyperemia: The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).

Research Excerpts

ExcerptRelevanceReference
"To gain insight into the role of adenosine (Ado) in exercise hyperemia, we compared forearm vasodilation induced by intra-arterial infusion of three doses of Ado with vasodilation during three workloads of forearm handgrip exercise in 27 human subjects."7.73Bimodal distribution of vasodilator responsiveness to adenosine due to difference in nitric oxide contribution: implications for exercise hyperemia. ( Charkoudian, N; Eisenach, JH; Joyner, MJ; Martin, EA; Nicholson, WT, 2006)
"This study was designed to test the hypothesis that endogenous adenosine participates in the global coronary functional hyperemia accompanying intracoronary infusions of norepinephrine (NE) and isoproterenol (ISO)."7.68Role of adenosine in catecholamine-induced global coronary functional hyperemia in isolated guinea pig hearts. ( Kang, YH; Merrill, GF; Wei, HM, 1990)
"Adenosine formation was inversely related to diastolic aortic pressure."5.28Transmural gradient of adenosine in canine heart during functional hyperemia. ( Borst, M; Deussen, A; Schrader, J; Walter, C, 1991)
"To gain insight into the role of adenosine (Ado) in exercise hyperemia, we compared forearm vasodilation induced by intra-arterial infusion of three doses of Ado with vasodilation during three workloads of forearm handgrip exercise in 27 human subjects."3.73Bimodal distribution of vasodilator responsiveness to adenosine due to difference in nitric oxide contribution: implications for exercise hyperemia. ( Charkoudian, N; Eisenach, JH; Joyner, MJ; Martin, EA; Nicholson, WT, 2006)
" This conclusion is strengthened by the observation that hypertrophic hearts from volume-overloaded rats had similar amounts of cardiac hypertrophy to the hearts from the hypertensive rats, without a change in flow, coronary vascular resistance or ischaemic sensitivity, whereas the hearts from isoproterenol-treated rats had lower ischaemic sensitivity and coronary vascular resistance."3.69Sensitivity to ischaemic ATP breakdown in different models of cardiac hypertrophy in rats. ( Harmsen, E; Leenen, FH; Ruzicka, M; Schoemaker, R; Yu, J, 1994)
"We tested the hypothesis that in the rat duodenum and intestine the mesenteric hyperemia due to beta-adrenoceptor stimulation is mediated by capsaicin-sensitive afferent nerves."3.69Primary afferent nerves mediate in part beta-adrenoceptor stimulation-induced mesenteric hyperemia in rats. ( Lam, K; Leung, FW; Leung, JW; Seno, K, 1996)
"This study was designed to test the hypothesis that endogenous adenosine participates in the global coronary functional hyperemia accompanying intracoronary infusions of norepinephrine (NE) and isoproterenol (ISO)."3.68Role of adenosine in catecholamine-induced global coronary functional hyperemia in isolated guinea pig hearts. ( Kang, YH; Merrill, GF; Wei, HM, 1990)
"Three stages of cardiac hypertrophy due to volume overload were recognized during the 16-wk period."1.32Characterization of cardiac hypertrophy and heart failure due to volume overload in the rat. ( Dhalla, NS; Liu, S; Ren, B; Sentex, E; Tappia, PS; Wang, X, 2003)
" Furthermore, the dose-response relation to isoproterenol was similar in both groups."1.28Limb vascular responsiveness to beta-adrenergic receptor stimulation in patients with congestive heart failure. ( Colucci, WS; Creager, MA; Quigg, RJ; Ren, CJ; Roddy, MA, 1991)
"Adenosine formation was inversely related to diastolic aortic pressure."1.28Transmural gradient of adenosine in canine heart during functional hyperemia. ( Borst, M; Deussen, A; Schrader, J; Walter, C, 1991)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199016 (55.17)18.7374
1990's8 (27.59)18.2507
2000's4 (13.79)29.6817
2010's1 (3.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ross, AJ1
Gao, Z1
Pollock, JP1
Leuenberger, UA1
Sinoway, LI1
Muller, MD1
Wang, X1
Ren, B1
Liu, S1
Sentex, E1
Tappia, PS1
Dhalla, NS1
Björkman, JA1
Jern, S1
Jern, C1
HARRISON, RG1
BROWN, KN1
Martin, EA1
Nicholson, WT1
Eisenach, JH1
Charkoudian, N1
Joyner, MJ1
Fernández, N2
Monge, L2
García-Villalón, AL2
Diéguez, G2
García, JL1
Gomez, B1
Conter, RL1
Washington, JL1
Kauffman, GL1
Harmsen, E1
Schoemaker, R1
Yu, J1
Ruzicka, M1
Leenen, FH1
Seno, K1
Lam, K1
Leung, JW1
Leung, FW1
Laughlin, MH1
Diana, JN1
Tipton, CM1
Creager, MA1
Quigg, RJ1
Ren, CJ1
Roddy, MA1
Colucci, WS1
Kang, YH1
Wei, HM1
Merrill, GF1
Deussen, A1
Walter, C1
Borst, M1
Schrader, J1
Tanaka, T1
Fukumoto, T1
Ochi, T1
Kuroiwa, A1
Novikova, EB1
Serebriakova, LI1
Tskitishvili, OV1
Holland, MG1
Skinner, NS1
Webster, ME1
Reneman, RS1
Clarke, HF1
Simmons, N1
Spencer, MP1
Schroeder, W1
Rathscheck, W1
Khouri, EM1
Gregg, DE2
Lowensohn, HS1
Winbury, MM1
Howe, BB1
Hefner, MA1
Brown, JH1
Garrett, RL1
Hilton, SM1
Vrbová, G1
Pitt, B1
Geber, WF2
Schwinghamer, JM2
Juhász-Nagy, A1
Szentiványi, M1
Rácz, S1
Deák, G1
Coffman, JD1

Reviews

1 review available for isoproterenol and Hyperemia

ArticleYear
Autonomic drugs in ophthalmology: some problems and promises. Section III: Sympathomimetic drugs.
    Annals of ophthalmology, 1974, Volume: 6, Issue:9

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Aqueous Humor; Cats; Cornea; Depression, Chemical; Epi

1974

Trials

1 trial available for isoproterenol and Hyperemia

ArticleYear
β-Adrenergic receptor blockade impairs coronary exercise hyperemia in young men but not older men.
    American journal of physiology. Heart and circulatory physiology, 2014, Nov-15, Volume: 307, Issue:10

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Aging; Coronary Ves

2014

Other Studies

27 other studies available for isoproterenol and Hyperemia

ArticleYear
Characterization of cardiac hypertrophy and heart failure due to volume overload in the rat.
    Journal of applied physiology (Bethesda, Md. : 1985), 2003, Volume: 94, Issue:2

    Topics: Animals; Arteries; Cardiac Output, Low; Cardiomegaly; Coronary Circulation; Heart; Hemodynamics; Hyp

2003
Cardiac sympathetic nerve stimulation triggers coronary t-PA release.
    Arteriosclerosis, thrombosis, and vascular biology, 2003, Jun-01, Volume: 23, Issue:6

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Blood Pressure; Calcium Channel Blocke

2003
SUPRARENAL CORTICAL DEGENERATION FOLLOWING ISOPROTERENOL ADMINISTRATION IN THE RAT.
    Endocrinology, 1964, Volume: 75

    Topics: Adrenal Cortex; Adrenal Gland Diseases; Hemorrhage; Hyperemia; Isoproterenol; Pathology; Pharmacolog

1964
Bimodal distribution of vasodilator responsiveness to adenosine due to difference in nitric oxide contribution: implications for exercise hyperemia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2006, Volume: 101, Issue:2

    Topics: Acetylcholine; Adenosine; Adult; Brachial Artery; Dose-Response Relationship, Drug; Enzyme Inhibitor

2006
Coronary reactive hyperaemia and arterial pressure in anaesthetized goats.
    Experimental physiology, 2006, Volume: 91, Issue:5

    Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Coronary Vessels; Female; Goats; Heart; Hyperemia

2006
Cerebral reactive hyperaemia and arterial pressure in anaesthetized goats.
    Acta physiologica Scandinavica, 1995, Volume: 153, Issue:4

    Topics: Anesthesia; Animals; Aorta, Thoracic; Arteries; Blood Pressure; Cerebrovascular Circulation; Female;

1995
Stimulated pancreatic exocrine secretion does not require pancreatic hyperemia in rats. Potential cholinergic role.
    Digestive diseases and sciences, 1993, Volume: 38, Issue:7

    Topics: Animals; Atropine; Deoxyglucose; Dose-Response Relationship, Drug; Hydrogen; Hyperemia; Isoprotereno

1993
Sensitivity to ischaemic ATP breakdown in different models of cardiac hypertrophy in rats.
    Journal of hypertension, 1994, Volume: 12, Issue:1

    Topics: Adenosine Triphosphate; Animals; Cardiomegaly; Coronary Circulation; Hyperemia; Hypertension; Isopro

1994
Primary afferent nerves mediate in part beta-adrenoceptor stimulation-induced mesenteric hyperemia in rats.
    Life sciences, 1996, Volume: 59, Issue:15

    Topics: Afferent Pathways; Animals; Capsaicin; Denervation; Duodenum; Hyperemia; Intestinal Mucosa; Isoprote

1996
Effects of exercise training on coronary reactive hyperemia and blood flow in the dog.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1978, Volume: 45, Issue:4

    Topics: Animals; Blood Pressure; Coronary Circulation; Dogs; Heart Rate; Hyperemia; Isoproterenol; Physical

1978
Limb vascular responsiveness to beta-adrenergic receptor stimulation in patients with congestive heart failure.
    Circulation, 1991, Volume: 83, Issue:6

    Topics: Adrenergic beta-Agonists; Adult; Catecholamines; Female; Forearm; Heart Failure; Humans; Hyperemia;

1991
Role of adenosine in catecholamine-induced global coronary functional hyperemia in isolated guinea pig hearts.
    Journal of cardiovascular pharmacology, 1990, Volume: 15, Issue:6

    Topics: Adenosine; Adenosine Deaminase; Animals; Carbon Dioxide; Catecholamines; Coronary Disease; Female; G

1990
Transmural gradient of adenosine in canine heart during functional hyperemia.
    The American journal of physiology, 1991, Volume: 260, Issue:3 Pt 2

    Topics: Adenosine; Animals; Cardiac Pacing, Artificial; Cytosol; Dogs; Hyperemia; Isoproterenol; Kinetics; M

1991
Theophylline inhibits isoproterenol-induced coronary dilatation in the isolated perfused rat heart.
    International journal of cardiology, 1990, Volume: 29, Issue:3

    Topics: Adenosine; Animals; Coronary Circulation; Hemodynamics; Hyperemia; In Vitro Techniques; Isoprotereno

1990
[Effect of a decrease in perfusion pressure on the alpha-adrenergic reactions of the coronary vessels].
    Kardiologiia, 1988, Volume: 28, Issue:8

    Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Vessels; Dogs; Female; Hyperemia; Isoprotere

1988
Kinins, beta-adrenergic receptors and functional vasodilatation in the submaxillary gland of the cat.
    The Journal of physiology, 1968, Volume: 195, Issue:3

    Topics: Animals; Atropine; Blood Flow Velocity; Blood Pressure; Bradykinin; Carboxypeptidases; Cats; Chorda

1968
In vivo comparison of electromagnetic and Doppler flowmeters: with special attention to the processing of the analogue Doppler flow signal.
    Cardiovascular research, 1973, Volume: 7, Issue:4

    Topics: Animals; Aorta; Blood Flow Velocity; Blood Pressure; Dogs; Electromagnetic Phenomena; Female; Femora

1973
Investigation of the influence of acetylcholine on the distribution of capillary flow in the skeletal muscle of the guinea pig by recording of the pO2 in the muscle tissue.
    Pflugers Archiv : European journal of physiology, 1973, Volume: 345, Issue:4

    Topics: Acetylcholine; Animals; Capillaries; Epinephrine; Guinea Pigs; Hyperemia; Isoproterenol; Muscles; No

1973
Flow in the major branches of the left coronary artery during experimental coronary insufficiency in the unanesthetized dog.
    Circulation research, 1968, Volume: 23, Issue:1

    Topics: Animals; Arteries; Blood Flow Velocity; Collateral Circulation; Coronary Disease; Coronary Vessels;

1968
Effect of nitrates and other coronary dilators on large and small coronary vessels: an hypothesis for the mechanism of action of nitrates.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 168, Issue:1

    Topics: Aminophylline; Animals; Aorta; Biophysical Phenomena; Biophysics; Blood Circulation; Blood Flow Velo

1969
Inhibition of constriction-induced reactive hyperemic edema.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 139, Issue:2

    Topics: Alphaprodine; Animals; Atropine; Constriction; Edema; Epinephrine; Hexamethonium Compounds; Hindlimb

1972
Absence of functional hyperaemia in the soleus muscle of the cat.
    The Journal of physiology, 1968, Volume: 194, Issue:2

    Topics: Acetylcholine; Animals; Blood Flow Velocity; Cats; Electric Stimulation; Epinephrine; Hindlimb; Hype

1968
Coronary hemodynamic effects of increasing ventricular rate in the unanesthetized dog.
    Circulation research, 1968, Volume: 22, Issue:6

    Topics: Animals; Aorta; Blood Circulation; Blood Pressure; Cardiac Output; Coronary Disease; Coronary Vessel

1968
Characteristics of reactive hyperemia in old and young dogs.
    Angiology, 1965, Volume: 16, Issue:10

    Topics: Acetylcholine; Aging; Animals; Blood Flow Velocity; Dogs; Epinephrine; Histamine; Hyperemia; Isoprot

1965
Coronary circulation of the avian heart.
    Archives internationales de pharmacodynamie et de therapie, 1965, Volume: 157, Issue:2

    Topics: Acetylcholine; Adaptation, Physiological; Animals; Birds; Blood Circulation; Coronary Vessels; Diben

1965
Peripheral collateral blood flow and vascular reactivity in the dog.
    The Journal of clinical investigation, 1966, Volume: 45, Issue:6

    Topics: Animals; Bradykinin; Collateral Circulation; Dogs; Epinephrine; Extremities; Femoral Artery; Hyperem

1966
Pharmacologic modifications of reactive hyperemia.
    Archives internationales de pharmacodynamie et de therapie, 1966, Volume: 159, Issue:2

    Topics: Acetylcholine; Animals; Blood Vessels; Blood Volume; Dogs; Epinephrine; Femoral Artery; Femoral Vein

1966