isoproterenol has been researched along with Hypercapnia in 40 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Hypercapnia: A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Isoproterenol and hypoxemia-hypercapnia will increase myocardial oxygen demand and could prove to be detrimental in severe asthma." | 9.07 | The effect of hypercapnia and hypoxemia on the cardiovascular responses to isoproterenol. ( Beasley, R; Bremner, P; Buckly, D; Burgess, C; Crane, J; Galletly, D; McHaffie, D; Purdie, G; Robinson, B, 1994) |
| "6 km/h), we studied the effect of ozone on ventilatory responses to hypercapnia and to hypoxia." | 7.66 | Mechanism of ozone-induced tachypneic response to hypoxia and hypercapnia in conscious dogs. ( Djokic, TD; Dumont, C; Graf, PD; Lee, LY; Nadel, JA, 1980) |
| "Substance P was added to methacholine precontracted bronchial rings with and without epithelium." | 5.37 | Carbon dioxide enhances substance P-induced epithelium-dependent bronchial smooth muscle relaxation in Sprague-Dawley rats. ( Choudhury, P; El Mays, TY; Green, FH; Hollenberg, MD; Saifeddine, M, 2011) |
| "Treatment with arachidonic acid after ischemia restored pial arteriolar dilation to hypercapnia." | 5.28 | Topical arachidonic acid restores pial arteriolar dilation to hypercapnia of postischemic newborn pig brain. ( Armstead, WM; Leffler, CW; Mirro, R; Shibata, M, 1992) |
| "Isoproterenol and hypoxemia-hypercapnia will increase myocardial oxygen demand and could prove to be detrimental in severe asthma." | 5.07 | The effect of hypercapnia and hypoxemia on the cardiovascular responses to isoproterenol. ( Beasley, R; Bremner, P; Buckly, D; Burgess, C; Crane, J; Galletly, D; McHaffie, D; Purdie, G; Robinson, B, 1994) |
| "The response of the pial artery to hypercapnia, hypotension and isoproterenol were monitored before and 1 hour after HI in piglets equipped with a cranial window." | 3.78 | Salvinorin A administration after global cerebral hypoxia/ischemia preserves cerebrovascular autoregulation via kappa opioid receptor in piglets. ( Armstead, WM; Liu, R; Ma, N; Riley, J; Wang, Z, 2012) |
| " With the use of cranial window techniques, we examined cerebral vascular responses to endothelium-dependent (hypercapnia and bradykinin) and endothelium-independent (isoproterenol and sodium nitroprusside) dilators during the recovery from bicuculline-induced seizures in saline controls and in animals pretreated with a HO inhibitor, tin protoporphyrin (SnPP)." | 3.72 | Endogenous heme oxygenase prevents impairment of cerebral vascular functions caused by seizures. ( Carratu, P; Fedinec, A; Leffler, CW; Parfenova, H; Pourcyrous, M, 2003) |
| " As reported previously, before ischemia, hypercapnia and isoproterenol dilated pial arteries and arterioles and hypercapnia but not isoproterenol increased cortical periarachnoid cerebrospinal fluid 6-keto-prostaglandin F1 alpha, measured as an index of cerebral cortical prostacyclin synthesis." | 3.68 | Superoxide scavengers do not prevent ischemia-induced alteration of cerebral vasodilation in piglets. ( Armstead, WM; Busija, DW; Leffler, CW; Mirro, R; Shibata, M; Thompson, CC, 1993) |
| " Diameter of one pial arteriole was determined during baseline conditions and topical application of 10(-5) M phorbol 12, 13-dibutyrate (PDB) and during subsequent application of one of the following: arterial hypercapnia (inhalation of 10% CO2), topical application of cerebrospinal fluid with 12 mM K+, or topical application of 10(-5) M isoproterenol in cerebrospinal fluid." | 3.68 | Reversal by increased CSF [H+] and [K+] of phorbol ester-induced arteriolar constriction in piglets. ( Busija, DW; Chen, J, 1992) |
| "We investigated the effects of aminophylline, isoproterenol, and neostigmine on decreased diaphragmatic contractility induced by hypercapnia." | 3.67 | Effects of aminophylline, isoproterenol, and neostigmine on hypercapnic depression of diaphragmatic contractility. ( Fitzgerald, RS; Howell, S; Roussos, C, 1985) |
| "6 km/h), we studied the effect of ozone on ventilatory responses to hypercapnia and to hypoxia." | 3.66 | Mechanism of ozone-induced tachypneic response to hypoxia and hypercapnia in conscious dogs. ( Djokic, TD; Dumont, C; Graf, PD; Lee, LY; Nadel, JA, 1980) |
| " Halothane anaesthesia sensitized the equine heart to the arrhythmogenic actions of adrenaline; the incidence and duration of ventricular arrhythmias being greater than in conscious animals." | 3.65 | Influence of halothane and catecholamines on heart rate and rhythm in the horse. ( Lees, P; Tavernor, WD, 1970) |
| "Hydrogen sulfide (H2S) is a gaseous signaling molecule that appears to be involved in numerous biological processes, including regulation of blood pressure and vascular tone." | 1.37 | Hydrogen sulfide and cerebral microvascular tone in newborn pigs. ( Basuroy, S; Fedinec, AL; Jaggar, JH; Leffler, CW; Parfenova, H; Umstot, ES, 2011) |
| "Substance P was added to methacholine precontracted bronchial rings with and without epithelium." | 1.37 | Carbon dioxide enhances substance P-induced epithelium-dependent bronchial smooth muscle relaxation in Sprague-Dawley rats. ( Choudhury, P; El Mays, TY; Green, FH; Hollenberg, MD; Saifeddine, M, 2011) |
| "Isoproterenol-induced PAD was unchanged by H/I, EEIIMD, SB-203580, and SP-600125." | 1.36 | PAI-1-derived peptide EEIIMD prevents impairment of cerebrovasodilation by augmenting p38 MAPK upregulation after cerebral hypoxia/ischemia. ( Armstead, WM; Cines, DB; Higazi, AA; Kiessling, JW; Riley, J, 2010) |
| "Before light/dye treatment, hypercapnia increased cortical periarachnoid 6-keto prostaglandin F1 alpha concentration approximately threefold." | 1.29 | Light/dye microvascular injury selectively eliminates hypercapnia-induced pial arteriolar dilation in newborn pigs. ( Armstead, WM; Leffler, CW; Mirro, R; Shanklin, DR; Shibata, M, 1994) |
| "Treatment with arachidonic acid after ischemia restored pial arteriolar dilation to hypercapnia." | 1.28 | Topical arachidonic acid restores pial arteriolar dilation to hypercapnia of postischemic newborn pig brain. ( Armstead, WM; Leffler, CW; Mirro, R; Shibata, M, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (57.50) | 18.7374 |
| 1990's | 7 (17.50) | 18.2507 |
| 2000's | 4 (10.00) | 29.6817 |
| 2010's | 5 (12.50) | 24.3611 |
| 2020's | 1 (2.50) | 2.80 |
| Authors | Studies |
|---|---|
| Harter, TS | 1 |
| Clifford, AM | 1 |
| Tresguerres, M | 1 |
| Pourcyrous, M | 2 |
| Chilakala, S | 1 |
| Elabiad, MT | 1 |
| Parfenova, H | 4 |
| Leffler, CW | 9 |
| Kiessling, JW | 2 |
| Cines, DB | 2 |
| Higazi, AA | 2 |
| Armstead, WM | 7 |
| Riley, J | 2 |
| Basuroy, S | 1 |
| Jaggar, JH | 1 |
| Umstot, ES | 1 |
| Fedinec, AL | 1 |
| El Mays, TY | 1 |
| Saifeddine, M | 1 |
| Choudhury, P | 1 |
| Hollenberg, MD | 1 |
| Green, FH | 1 |
| Wang, Z | 1 |
| Ma, N | 1 |
| Liu, R | 1 |
| Carratu, P | 1 |
| Fedinec, A | 1 |
| Vadász, I | 1 |
| Dada, LA | 1 |
| Briva, A | 1 |
| Trejo, HE | 1 |
| Welch, LC | 1 |
| Chen, J | 2 |
| Tóth, PT | 1 |
| Lecuona, E | 1 |
| Witters, LA | 1 |
| Schumacker, PT | 1 |
| Chandel, NS | 1 |
| Seeger, W | 1 |
| Sznajder, JI | 1 |
| Siesjö, BK | 1 |
| Lee, LY | 1 |
| Djokic, TD | 1 |
| Dumont, C | 1 |
| Graf, PD | 1 |
| Nadel, JA | 1 |
| Mirro, R | 4 |
| Shanklin, DR | 1 |
| Shibata, M | 4 |
| Zuckerman, S | 1 |
| Bremner, P | 1 |
| Burgess, C | 1 |
| McHaffie, D | 1 |
| Robinson, B | 1 |
| Galletly, D | 1 |
| Buckly, D | 1 |
| Beasley, R | 1 |
| Purdie, G | 1 |
| Crane, J | 1 |
| Thompson, CC | 1 |
| Busija, DW | 2 |
| Zuckerman, SL | 1 |
| Willis, AP | 1 |
| Yakaitis, RW | 1 |
| Dodge, TL | 1 |
| Thomas, JD | 1 |
| Deehan, R | 1 |
| Swanton, JG | 1 |
| Edvinsson, L | 1 |
| Lacombe, P | 1 |
| Owman, C | 1 |
| Reynier-Rebuffel, AM | 1 |
| Seylaz, J | 1 |
| de Castuma, ES | 1 |
| Mattiazzi, AR | 1 |
| Cingolani, HE | 1 |
| Taylor, JF | 1 |
| Lee, JC | 1 |
| Downing, SE | 1 |
| Scarpelli, EM | 1 |
| Agasso, EJ | 1 |
| Ingram, RH | 1 |
| Howell, S | 1 |
| Fitzgerald, RS | 1 |
| Roussos, C | 1 |
| Lluch, S | 1 |
| Diéguez, G | 1 |
| García, AL | 1 |
| Gómez, B | 1 |
| Baïsset, A | 1 |
| Cotonat, J | 1 |
| Montastruc, P | 1 |
| Sant'Ambrogio, G | 1 |
| Miserocchi, G | 1 |
| Mortola, J | 1 |
| Rodarte, JR | 1 |
| Hyatt, RE | 1 |
| Atkinson, JM | 1 |
| Rand, MJ | 1 |
| Blackburn, JP | 1 |
| Conway, CM | 1 |
| Leigh, JM | 1 |
| Lindop, MJ | 1 |
| Reitan, JA | 1 |
| Edelman, NH | 1 |
| Epstein, P | 1 |
| Cherniack, NS | 1 |
| Fishman, AP | 1 |
| Clark, DG | 1 |
| Tinston, DJ | 1 |
| Cho, YW | 1 |
| Aviado, DM | 1 |
| Lish, PM | 1 |
| Lees, P | 1 |
| Tavernor, WD | 1 |
| Rebuck, AS | 1 |
| Read, J | 1 |
| Shimizu, H | 1 |
| Carey, JP | 1 |
| Stemmer, EA | 1 |
| List, JW | 1 |
| Chin, SC | 1 |
| Heber, R | 1 |
| Connolly, JE | 1 |
1 review available for isoproterenol and Hypercapnia
| Article | Year |
|---|---|
Cerebral metabolic rate in hypercarbia--a controversy.
Topics: Amino Acids; Animals; Brain; Carbon Dioxide; Cerebrovascular Circulation; Citric Acid Cycle; Diazepa | 1980 |
1 trial available for isoproterenol and Hypercapnia
| Article | Year |
|---|---|
The effect of hypercapnia and hypoxemia on the cardiovascular responses to isoproterenol.
Topics: Adult; Analysis of Variance; Carbon Dioxide; Cardiovascular System; Humans; Hypercapnia; Hypoxia; Is | 1994 |
38 other studies available for isoproterenol and Hypercapnia
| Article | Year |
|---|---|
Adrenergically induced translocation of red blood cell β-adrenergic sodium-proton exchangers has ecological relevance for hypoxic and hypercapnic white seabass.
Topics: Acclimatization; Adrenergic beta-Agonists; Animals; Bass; Ecosystem; Erythrocytes; Fish Proteins; Hy | 2021 |
Does prolonged severe hypercapnia interfere with normal cerebrovascular function in piglets?
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Animals, Newborn; Arter | 2018 |
Inhibition of integrin alphavbeta3 prevents urokinase plasminogen activator-mediated impairment of cerebrovasodilation after cerebral hypoxia/ischemia.
Topics: Adrenergic beta-Agonists; Animals; Animals, Newborn; Antibodies; Cerebrovascular Circulation; Diseas | 2009 |
PAI-1-derived peptide EEIIMD prevents impairment of cerebrovasodilation by augmenting p38 MAPK upregulation after cerebral hypoxia/ischemia.
Topics: Animals; Animals, Newborn; Anthracenes; Blood Pressure; Carbon Dioxide; Cardiovascular Agents; Cereb | 2010 |
Hydrogen sulfide and cerebral microvascular tone in newborn pigs.
Topics: Animals; Animals, Newborn; Arterioles; Brain Chemistry; Capillaries; Cerebrovascular Circulation; Cy | 2011 |
Carbon dioxide enhances substance P-induced epithelium-dependent bronchial smooth muscle relaxation in Sprague-Dawley rats.
Topics: Animals; Bronchi; Calcium; Carbon Dioxide; Drug Synergism; Epithelium; Hydrogen-Ion Concentration; H | 2011 |
Salvinorin A administration after global cerebral hypoxia/ischemia preserves cerebrovascular autoregulation via kappa opioid receptor in piglets.
Topics: Administration, Intravenous; Animals; Animals, Newborn; Cerebral Arteries; Cerebrovascular Circulati | 2012 |
Endogenous heme oxygenase prevents impairment of cerebral vascular functions caused by seizures.
Topics: Adrenergic beta-Agonists; Animals; Animals, Newborn; Arachnoid; Bradykinin; Capillaries; Carbon Mono | 2003 |
AMP-activated protein kinase regulates CO2-induced alveolar epithelial dysfunction in rats and human cells by promoting Na,K-ATPase endocytosis.
Topics: Adrenergic beta-Agonists; AMP-Activated Protein Kinases; Animals; Calcium; Calcium-Calmodulin-Depend | 2008 |
Mechanism of ozone-induced tachypneic response to hypoxia and hypercapnia in conscious dogs.
Topics: Animals; Atropine; Bronchi; Constriction; Dogs; Hypercapnia; Hypoxia; Isoproterenol; Ozone; Respirat | 1980 |
Light/dye microvascular injury selectively eliminates hypercapnia-induced pial arteriolar dilation in newborn pigs.
Topics: Animals; Animals, Newborn; Arterioles; Carbon Dioxide; Fluorescein; Fluoresceins; Hypercapnia; Ilopr | 1994 |
Inhibitory effect of indomethacin on prostacyclin receptor-mediated cerebral vascular responses.
Topics: Animals; Animals, Newborn; Arterioles; Aspirin; Cerebrovascular Circulation; Hypercapnia; Iloprost; | 1995 |
Superoxide scavengers do not prevent ischemia-induced alteration of cerebral vasodilation in piglets.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Animals, Newborn; Brain Ischemia; Catalase; Cerebrovascular C | 1993 |
Transforming growth factor-beta attenuates ischemia-induced alterations in cerebrovascular responses.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Animals, Newborn; Arterioles; Brain Ischemia; Cerebral Cortex | 1993 |
Endothelial NO and prostanoid involvement in newborn and juvenile pig pial arteriolar vasomotor responses.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Age Factors; Animals; Animals, Newborn; Arterioles; Bra | 2001 |
Effects of catecholamines during respiratory alkalosis in dogs.
Topics: Alkalosis, Respiratory; Animals; Blood Pressure; Cardiac Output; Dogs; Dopamine; Epinephrine; Heart | 1978 |
The influence of hypoxia and hypercapnia on the cardiotoxicity of isoprenaline in dogs [proceedings].
Topics: Animals; Dogs; Heart Diseases; Hypercapnia; Hypoxia; Isoproterenol | 1978 |
Quantitative changes in regional cerebral blood flow of rats induced by alpha- and beta-adrenergic stimulants.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Carbon Dioxide; Cerebrovascular Circul | 1979 |
Effect of hypercapnic acidosis on induction of arrhythmias by catecholamines in cat papillary muscles.
Topics: Acid-Base Equilibrium; Acidosis; Animals; Cats; Hypercapnia; Isoproterenol; Muscle Contraction; Musc | 1977 |
Effects of acidosis, catechols, and atrial function on pulmonary pressure gradients.
Topics: Acidosis; Animals; Blood Flow Velocity; Blood Pressure; Carbon Dioxide; Cardiac Output; Cats; Female | 1975 |
Arterial pH, airway caliber and response to acetylcholine and catecholamines in vivo.
Topics: Acetylcholine; Acidosis; Animals; Bicarbonates; Catecholamines; Dogs; Epinephrine; Hypercapnia; Isop | 1979 |
Arterial oxygenation differences with carbon dioxide-induced versus voluntary increases in minute ventilation in chronic airway obstruction.
Topics: Airway Obstruction; Bronchitis; Chronic Disease; Humans; Hypercapnia; Hyperventilation; Isoprotereno | 1977 |
Topical arachidonic acid restores pial arteriolar dilation to hypercapnia of postischemic newborn pig brain.
Topics: Administration, Topical; Animals; Animals, Newborn; Arachidonic Acid; Arterioles; Brain; Brain Ische | 1992 |
Reversal by increased CSF [H+] and [K+] of phorbol ester-induced arteriolar constriction in piglets.
Topics: Animals; Animals, Newborn; Arterioles; Colforsin; Hydrogen; Hypercapnia; Indomethacin; Isoproterenol | 1992 |
Effects of aminophylline, isoproterenol, and neostigmine on hypercapnic depression of diaphragmatic contractility.
Topics: Aminophylline; Animals; Diaphragm; Dogs; Electric Stimulation; Hypercapnia; Isoproterenol; Muscle Co | 1985 |
Rete mirabile of goat: its flow-damping effect on cerebral circulation.
Topics: Acetylcholine; Animals; Blood Pressure; Carotid Arteries; Cerebral Arteries; Cerebrovascular Circula | 1985 |
[Enhancement of cardiac and intestinal effects of adrenaline by gaseous hypocapnic alkalosis in the dog].
Topics: Alkalosis; Animals; Cardiac Output; Dogs; Electrocardiography; Epinephrine; Ethanolamines; Hydrogen- | 1967 |
Transient responses of pulmonary stretch receptors in the dog to inhalation of carbon dioxide.
Topics: Acetazolamide; Animals; Carbon Dioxide; Dogs; Hypercapnia; Isoproterenol; Mechanoreceptors; Pulmonar | 1974 |
Effect of acute exposure to CO 2 on lung mechanics in normal man.
Topics: Adult; Airway Resistance; Carbon Dioxide; Conductometry; Esophagus; Humans; Hypercapnia; Isoproteren | 1973 |
Reduction of cardiovascular responses to some sympathomimetic amines during hypercapnia.
Topics: Adrenalectomy; Animals; Blood Gas Analysis; Blood Pressure; Carbon Dioxide; Cardiac Volume; Epinephr | 1972 |
Pa CO2 and the pre-ejection period: the pa CO2 inotropy response curve.
Topics: Adult; Age Factors; Aged; Anesthesia, General; Animals; Biomechanical Phenomena; Carbon Dioxide; Dog | 1972 |
Control of cerebral blood flow in the goat; role of the carotid rete.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Brain; Carbon Dioxide; Carotid Arteries; Cerebrovascul | 1972 |
Cardiac effects of isoproterenol, hypoxia, hypercapnia and fluorocarbon propellants and their use in asthma inhalers.
Topics: Aerosols; Animals; Arrhythmias, Cardiac; Asthma; Bronchodilator Agents; Dogs; Fluorocarbon Polymers; | 1972 |
Efficacy of a new bronchodilator, soterenol, on experimental locked-lung syndrome in dogs.
Topics: Anilides; Animals; Asthma; Bronchodilator Agents; Dogs; Female; Histamine; Hypercapnia; Isoprotereno | 1968 |
Influence of halothane and catecholamines on heart rate and rhythm in the horse.
Topics: Anesthesia, Inhalation; Animals; Arrhythmias, Cardiac; Atropine; Catecholamines; Consciousness; Epin | 1970 |
Patterns of ventilatory response to carbon dioxide during recovery from severe asthma.
Topics: Adolescent; Adult; Asthma; Carbon Dioxide; Child; Female; Humans; Hypercapnia; Isoproterenol; Male; | 1971 |
[Pharmacological and physiological studies on renal circulation. (4). Effects of changes in blood gas tension on the circulation of the perfused kidney].
Topics: Acetylcholine; Animals; Blood Gas Analysis; Blood Pressure; Carbon Dioxide; Chloralose; Dogs; Electr | 1967 |
The hazards of using vasoactive drugs to augment peripheral and cerebral blood flow.
Topics: Anesthesia, General; Animals; Arteries; Blood Gas Analysis; Blood Pressure; Blood Volume Determinati | 1969 |