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isoproterenol and Goldblatt Syndrome

isoproterenol has been researched along with Goldblatt Syndrome in 21 studies

Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.

Research Excerpts

ExcerptRelevanceReference
"Previous studies from our laboratory, have demonstrated that 21 days after unclipping the decrease in arterial pressure (AP) was followed by a regression of cardiac hypertrophy (CH) and a normalization of contractile response to Isoproterenol (I) stimulation in two kidney one clip (2K1C) hypertension."3.68[Effect of alpha methyldopa on heart in renovascular hypertension]. ( Fontan, M; Gallo, A; Gómez Llambi, H; Kuraja, I; Massadi, A; Taquini, CM, 1990)
" Serum angiotensin converting enzyme activity (ACEA) and plasma renin activity (PRA) were determined in rats under different experimental conditions such as: nephrotic syndrome (NS), bilateral nephrectomy (BN), renovascular hypertension (RH), dehydration (DEH), anaesthesia (AN), low sodium diet (LSD) and high sodium diet (HSD), and injection with propranolol (PRO) and isoprenaline (ISO)."3.68Serum angiotensin converting enzyme activity and plasma renin activity in experimental models of rats. ( Cruz, C; Ibarra-Rubio, ME; Pedraza-Chaverrí, J; Peña, JC; Tapia, E, 1990)
"In captopril-treated rabbits, 1 microM (+/-)-isoproterenol increased I(Ca,L) by 110 +/- 11% (n = 17)."1.31Effects of captopril treatment of renovascular hypertension on beta-adrenergic modulation of L-type Ca(2+) current. ( Kowey, PR; Liu, T; Marinchak, RA; Rials, SJ; Wu, Y; Xu, X, 2000)
"A model of renovascular hypertension has been developed in the guinea pig using the Goldblatt (2-kidney, 1-clip) operation."1.29Characteristics of myocytes isolated from hearts of renovascular hypertensive guinea pigs. ( del Monte, F; Harding, SE; MacLeod, KT; Naqvi, RU; O'Gara, P, 1994)
"It is not clear whether regression of cardiac hypertrophy normalizes cardiac contractility."1.28Effect of enalapril on the inotropic response to isoproterenol in renal hypertensive rats. ( Fontán, M; Gómez Llambí, H; Mazzadi, A; Taquini, CM, 1992)
" In conscious instrumented normotensive rats and dogs, intravenous and oral administration of BW A575C causes a dose-dependent rightward displacement of the pressor dose-response curve to angiotensin I (dose ratio of 29."1.27BW A575C: pharmacological profile in vivo of a novel angiotensin converting enzyme inhibitor and beta-blocker. ( Allan, G; Cambridge, D; Follenfant, MJ; Ford, A; Hardy, GW; Oliver, PL, 1987)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19906 (28.57)18.7374
1990's10 (47.62)18.2507
2000's5 (23.81)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jackson, EK1
Mi, Z1
Callera, GE1
Yeh, E1
Tostes, RC1
Caperuto, LC1
Carvalho, CR1
Bendhack, LM1
Ge, C2
Garcia, R2
Anand-Srivastava, MB2
Matzdorf, C1
Kurtz, A1
Höcherl, K1
Ayobe, MH1
Tarazi, RC1
Naqvi, RU1
del Monte, F1
O'Gara, P1
Harding, SE1
MacLeod, KT1
Bell, DR1
Dec, EM1
Rensberger, HJ1
Zimmerman, BG1
Birt, PC1
Xu, X1
Rials, SJ1
Wu, Y1
Liu, T1
Marinchak, RA1
Kowey, PR1
Gómez Llambí, H3
Mazzadi, A1
Fontán, M2
Taquini, CM2
Cabral, AM2
Vasquez, EC3
Moore, RL1
Yelamarty, RV1
Misawa, H1
Scaduto, RC1
Pawlush, DG1
Elensky, M1
Cheung, JY1
Kuraja, I1
Massadi, A1
Gallo, A1
Ibarra-Rubio, ME1
Cruz, C1
Tapia, E1
Peña, JC1
Pedraza-Chaverrí, J1
Vassallo, DV2
Mill, JG1
Cambridge, D1
Allan, G1
Hardy, GW1
Follenfant, MJ1
Ford, A1
Oliver, PL1
Gende, OA1
Mattiazzi, A1
Camilion, MC1
Pedroni, P1
Taquini, C1
Cingolani, HE1
Davidson, WR1
Kawashima, S1
Banerjee, SP1
Liang, CS1
Vargas, F1
Casanova, I1
Fernández, MA1
Haro, JM1
García del Río, C1

Other Studies

21 other studies available for isoproterenol and Goldblatt Syndrome

ArticleYear
Regulation of renovascular adenosine 3',5'-cyclic monophosphate in spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:2

    Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Analysis of Variance; Animals; Blood Pressure; Blood

2009
Changes in the vascular beta-adrenoceptor-activated signalling pathway in 2Kidney-1Clip hypertensive rats.
    British journal of pharmacology, 2004, Volume: 141, Issue:7

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Aorta, Thoracic; Caffeine; Calcium-Transporting ATP

2004
Enhanced expression of Gialpha protein and adenylyl cyclase signaling in aortas from 1 kidney 1 clip hypertensive rats.
    Canadian journal of physiology and pharmacology, 2006, Volume: 84, Issue:7

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Angiotensin II; Animals; Antihypertensive Agents; Ao

2006
COX-2 activity determines the level of renin expression but is dispensable for acute upregulation of renin expression in rat kidneys.
    American journal of physiology. Renal physiology, 2007, Volume: 292, Issue:6

    Topics: Adrenergic beta-Agonists; Angiotensin II Type 1 Receptor Blockers; Animals; Cyclooxygenase 2; Cycloo

2007
Beta-adrenoceptors and responsiveness in cardiac hypertrophy associated with renal hypertension in renovascular hypertensive rats.
    Clinical science (London, England : 1979), 1984, Volume: 67, Issue:1

    Topics: Animals; Cardiomegaly; Disease Models, Animal; Dose-Response Relationship, Drug; Heart; Heart Rate;

1984
Characteristics of myocytes isolated from hearts of renovascular hypertensive guinea pigs.
    The American journal of physiology, 1994, Volume: 266, Issue:5 Pt 2

    Topics: Animals; Blood Pressure; Body Weight; Calcium; Cell Nucleus; Cells, Cultured; Electric Stimulation;

1994
Selective effect of high arterial pressure in hypertension upon inhibition of cGMP versus cAMP mediated vascular relaxation.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 1996, Volume: 18, Issue:6

    Topics: Animals; Aorta, Abdominal; Aorta, Thoracic; Blood Pressure; Bucladesine; Cyclic AMP; Cyclic GMP; Hyp

1996
Angiotensin II release from rabbit intrarenal arteries: a critical assessment.
    American journal of hypertension, 1997, Volume: 10, Issue:3

    Topics: Adrenergic beta-Agonists; Angiotensin II; Animals; Arteries; Chromium Radioisotopes; Hypertension, R

1997
Effects of captopril treatment of renovascular hypertension on beta-adrenergic modulation of L-type Ca(2+) current.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:1

    Topics: Animals; Calcium Channels; Captopril; Colforsin; Dose-Response Relationship, Drug; Drug Interactions

2000
Altered expression of Gi-protein and adenylyl cyclase activity in hearts from one kidney one clip hypertensive rats: effect of captopril.
    Journal of hypertension, 1999, Volume: 17, Issue:11

    Topics: Adenylyl Cyclases; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Colforsin; Glucagon

1999
Effect of enalapril on the inotropic response to isoproterenol in renal hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1992, Volume: 19, Issue:2 Suppl

    Topics: Animals; Body Weight; Cardiomegaly; Enalapril; Hypertension, Renovascular; Isoproterenol; Male; Musc

1992
Time course of cardiac sympathetic and vagal tone changes in renovascular hypertensive rats.
    American journal of hypertension, 1991, Volume: 4, Issue:10 Pt 1

    Topics: Animals; Atropine; Female; Heart; Hypertension, Renovascular; Isoproterenol; Male; Myocardium; Propr

1991
Altered Ca2+ dynamics in single cardiac myocytes from renovascular hypertensive rats.
    The American journal of physiology, 1991, Volume: 260, Issue:2 Pt 1

    Topics: Analysis of Variance; Animals; Calcium; Calcium Channel Blockers; Cardiomegaly; Cells, Cultured; Fur

1991
[Effect of alpha methyldopa on heart in renovascular hypertension].
    Medicina, 1990, Volume: 50, Issue:2

    Topics: Animals; Blood Pressure; Cardiomegaly; Heart Rate; Hypertension, Renovascular; Isoproterenol; Male;

1990
Serum angiotensin converting enzyme activity and plasma renin activity in experimental models of rats.
    Clinical and experimental pharmacology & physiology, 1990, Volume: 17, Issue:6

    Topics: Animals; Disease Models, Animal; Hypertension, Renovascular; Isoproterenol; Kidney Diseases; Male; N

1990
Myocardial depression produced by unilateral nephrectomy in rats.
    Clinical and experimental hypertension. Part A, Theory and practice, 1990, Volume: 12, Issue:4

    Topics: Animals; Blood Pressure; Heart; Heart Rate; Hypertension, Renovascular; Isoproterenol; Male; Myocard

1990
BW A575C: pharmacological profile in vivo of a novel angiotensin converting enzyme inhibitor and beta-blocker.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 11

    Topics: Adrenergic beta-Antagonists; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood

1987
Renal hypertension impairs inotropic isoproterenol effect without beta-receptor changes.
    The American journal of physiology, 1985, Volume: 249, Issue:4 Pt 2

    Topics: Animals; Calcium Chloride; Cardiomegaly; Hypertension, Renovascular; Isoproterenol; Male; Myocardial

1985
Preserved cardiac beta-adrenergic sensitivity in early renovascular hypertension.
    Hypertension (Dallas, Tex. : 1979), 1987, Volume: 9, Issue:5

    Topics: Adenylyl Cyclases; Animals; Blood Pressure; Dogs; Guanidines; Heart Rate; Heart Ventricles; Hemodyna

1987
Contractile performance of papillary muscles of renovascular hypertensive and isoproterenol-pretreated rats.
    Pharmacological research communications, 1988, Volume: 20, Issue:1

    Topics: Animals; Blood Pressure; Denervation; Heart Rate; Hypertension, Renovascular; Isoproterenol; Male; M

1988
[Water intake induced by isoprenaline in 2 models of experimental hypertension in rats].
    Revista espanola de fisiologia, 1987, Volume: 43, Issue:4

    Topics: Animals; Desoxycorticosterone; Drinking; Hypertension; Hypertension, Renovascular; Isoproterenol; Ma

1987