isoproterenol has been researched along with Glioma in 157 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
Excerpt | Relevance | Reference |
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"The beta-adrenoceptor-coupled adenylate cyclase system in rat C6 glioma cells displays many characteristics observed in brain tissue: using nonlinear regression analysis of agonist competition binding curves, we demonstrated that the bulk of beta-adrenoceptors show high nanomolar affinity for isoproterenol; like in brain tissue, Gpp(NH)p does not shift agonist competition binding curves to the right; and the agonist isoproterenol rapidly downregulates the number of beta-adrenoceptors and deamplifies the norepinephrine signal." | 7.68 | The beta-adrenoceptor-coupled adenylate cyclase system in rat C6 glioma cells. Deamplification by isoproterenol and oxaprotiline. ( Bieck, PR; Duhl, DM; Gillespie, DD; Manier, DH; Sulser, F, 1992) |
" In the present study, 2-aminopurine, which has been reported to selectively block c-fos gene expression, was used to test the hypothesis that c-fos protein might be involved in the desensitization to catecholamines was observed in 2-aminopurine-treated C6-2B rat glioma cells." | 7.68 | 2-Aminopurine inhibits RNA and protein synthesis and reduces catecholamine desensitization in C6-2B rat glioma cells. ( Brooker, G; DeBernardi, MA, 1992) |
"Nano- and micromolar isoproterenol concentrations were compared by studying cyclic AMP, beta-adrenoceptor density and beta 1-adrenoceptor mRNA in rat C6 glioma cells." | 7.68 | Dose-dependent down-regulation of beta-adrenoceptors by isoproterenol in rat C6 glioma cells. ( Bieck, PR; Duhl, DM; Eiring, A; Gillespie, DD; Manier, DH; Sulser, F, 1992) |
"Evidence is presented that isoproterenol treatment of rat C6 glioma cells, under conditions that increase glioma cell cAMP levels, causes the phosphorylative modification of several RNA polymerase II subunits." | 7.67 | Phosphorylation of rat C6 glioma cell DNA-dependent RNA polymerase II in vivo. Identification of phosphorylated subunits and modulation of phosphorylation by isoproterenol and N6,O2'-dibutyryl cyclic AMP. ( Jungmann, RA; Lee, SK; Schweppe, JS, 1984) |
"C6 glioma cells respond to beta-adrenergic agonists (isoproterenol) with a transient rise in intracellular cyclic adenosine monophosphate level." | 7.67 | Neuroblastoma membranes inhibit isoproterenol-stimulated rise of cAMP in glioma cells. ( de Vellis, J; Wu, DK, 1984) |
"When added to intact C6 glioma cells in the micromolar range of concentrations, ADP and ATP induce an inhibition of the isoproterenol-elicited cAMP responses." | 7.67 | ADP and, indirectly, ATP are potent inhibitors of cAMP production in intact isoproterenol-stimulated C6 glioma cells. ( Labouesse, J; Merle, M; Pianet, I, 1989) |
"Rat glioma C6 cells, cultured in the presence of the tricyclic antidepressant desipramine, lost a significant number of beta-adrenergic receptors in a time- and dose-dependent manner." | 7.67 | Effect of the tricyclic antidepressant desipramine on beta-adrenergic receptors in cultured rat glioma C6 cells. ( Finberg, JP; Fishman, PH, 1987) |
"Persistent stimulation with isoproterenol of the beta adrenergic receptor located in C6 glioma cell membranes results in a rapid rise in the cyclic AMP content, an activation of soluble cyclic AMP-dependent protein kinase, a translocation of catalytic subunits of the activated protein kinase to the nucleus and a delayed (3--4 hr later) increase of cyclic AMP phosphodiesterase activity and beta-nerve growth factor content." | 7.66 | beta Adrenergic receptor-mediated regulation of cyclic nucleotide phosphodiesterase in C6 glioma cells: vinblastine blockade of isoproterenol induction. ( Costa, E; Schwartz, JP, 1980) |
"The beta-adrenergic receptor of C6 glioma cells contains a disulfide bridge which can be reduced by dithiothreitol (DTT)." | 7.66 | Irreversible inactivation of beta-adrenergic receptors of C6 glioma cells. Synthesis and study of a thiol derivative of propranolol. ( Bockaert, J; Gozlan, H; Homburger, V; Lucas, M; Michelot, R, 1980) |
"The mechanism of isoproterenol and N6,O2-dibutyryl adenosine 3':5'-monophosphate (dibutyryl cAMP) induction of lactate dehydrogenase A subunit mRNA (mRNALDH) was investigated in the rat C6 glioma cell line." | 7.66 | Cyclic AMP regulation of lactate dehydrogenase. Isoproterenol and N6,O2-dibutyryl cyclic amp increase the rate of transcription and change the stability of lactate dehydrogenase a subunit messenger RNA in rat C6 glioma cells. ( Jungmann, RA; Kelley, DC; Miles, MF; Milkowski, DM, 1983) |
"Chronic in vitro treatment of C6 glioma cells with idazoxan did not significantly affect cholera or pertussis toxin catalyzed ribosylation of Gs and Gi/Go in these cells." | 5.28 | Idazoxan down-regulates beta-adrenoceptors on C6 glioma cells in vitro. ( Bitran, JA; Chen, G; Gusovsky, F; Manji, HK; Potter, WZ, 1992) |
"In this communication, we demonstrate that an increase in intracellular cAMP by 1) addition of dibutyrylic cAMP (dbcAMP), a membrane-permeable cAMP-analogue, or 2) activation of the β-adrenoceptor with (-)-isoproterenol, down regulates the levels of ecto-nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) mRNA, NPP1 protein and ecto-NPPase activity in rat C6 glioma cells." | 3.77 | Cyclic AMP-dependent down regulation of ecto-nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) in rat C6 glioma. ( Aerts, I; Grobben, B; Slegers, H; Van Ostade, X, 2011) |
"Treatment of rat glioma C6 cells with the beta-receptor agonist isoproterenol induces a massive increase in cAMP." | 3.74 | Volatile anesthetics affect the morphology of rat glioma C6 cells via RhoA, ERK, and Akt activation. ( Gambaryan, S; Roewer, N; Tas, PW, 2007) |
"Previously, we suggested that dioleoyl phosphatidic acid (PA) and lysophosphatidic acid (LPA) increased [Ca(2+)](i) through endogenous LPA receptors coupled to pertussis toxin-sensitive G proteins in rat C6 glioma cells." | 3.74 | Dioleoyl phosphatidic acid induces morphological changes through an endogenous LPA receptor in C6 glioma cells. ( Chang, YJ; Im, DS; Jo, JY; Kim, HL; Kim, YL; Kyeok, K, 2008) |
" Using RNase protection assays, we have determined that chronic isoproterenol exposure of rat C6 glioma cells results in the accelerated reduction of beta1-AR mRNAs." | 3.71 | Agonist-mediated down-regulation of rat beta1-adrenergic receptor transcripts: role of potential post-transcriptional degradation factors. ( Bai, Y; Brewer, G; Kirigiti, P; Li, B; Li, X; Machida, CA; Yang, YF, 2001) |
"Exposure of rat C6 glioma cells to the beta-adrenergic receptor agonist isoproterenol potentiates basal and metabotropic glutamate receptor-stimulated phospholipase C activity in rat C6 glioma cells." | 3.70 | Cross-talk between beta-adrenergic and metabotropic glutamate receptors in rat C6 glioma cells. ( Albasanz, JL; Fernández, M; Martín, M; Ros, M, 1998) |
" Rat C6 glioma cells were stimulated with isoproterenol and the protein lysates were resolved by 2-DGE." | 3.70 | Probing for drug-induced multiplex signal transduction pathways using high resolution two-dimensional gel electrophoresis: application to beta-adrenoceptor stimulation in the rat C6 glioma cell. ( Khawaja, XZ; Storm, SM, 1999) |
"Incubation of C6 glioma cells in the presence of aminoglutethimide, an inhibitor of cholesterol metabolism, together with either adenosine 3',5'-cyclic monophosphate (cAMP) analogues or agents that increase cAMP synthesis, such as cholera toxin, forskolin, and isoproterenol, stimulated the rate of pregnenolone formation by their isolated mitochondria." | 3.69 | Regulation of C6 glioma cell steroidogenesis by adenosine 3',5'-cyclic monophosphate. ( Guarneri, P; Papadopoulos, V, 1994) |
"Pretreatment of 1321N1 human astrocytoma cells with exogenously added bacterial phospholipase C (PLC) induced an increase in subsequent stimulation of cyclic AMP accumulation by the beta-adrenergic receptor agonist isoproterenol and by the direct adenylyl cyclase activator forskolin, a phenomenon referred to as sensitization." | 3.69 | Modulation of cyclic AMP accumulation in glial cells by exogenous phospholipase C. ( Hoffman, J; Toews, M; Whittle, S, 1996) |
"Microtubule disrupter, colchicine, and microtubule stabilizer, taxol, were used to determine whether microtubules play a role in beta-adrenergic receptor mRNA homeostasis and agonist-induced down-regulation in C6 glioma cells." | 3.69 | Regulation of beta-adrenergic receptor mRNA in rat C6 glioma cells is sensitive to the state of microtubule assembly. ( Chuang, DM; Fukamauchi, F; Hough, C, 1994) |
" Dibutyryl cAMP (dbcAMP) at 1 mM and isoproterenol at 10 microM inhibited MAP kinase activation and DNA synthesis potentiation with bFGF and platelet-derived growth factor to the control level in cultured astrocytes and C6 glioma cells." | 3.69 | Cyclic AMP inhibits activation of mitogen-activated protein kinase and cell proliferation in response to growth factors in cultured rat cortical astrocytes. ( Fukunaga, K; Kurino, M; Miyamoto, E; Ushio, Y, 1996) |
"The treatment of rat glioma C6 cells with 10 microM isoproterenol (Ipt) for 4 days upregulated the expression of the myelin-associated glycoprotein (MAG) gene by approximately 55-fold over the control value." | 3.69 | Transcriptional regulation of myelin associated glycoprotein gene expression by cyclic AMP. ( Konat, GW; Laszkiewicz, I; Wiggins, RC; Ye, P, 1994) |
"Adenine nucleotides inhibited isoproterenol- and forskolin-stimulated cyclic AMP accumulation in C6-2B rat glioma cells." | 3.68 | Identification of a P2Y-purinergic receptor that inhibits adenylyl cyclase. ( Boyer, JL; Chen, XH; Harden, TK; Lazarowski, ER, 1993) |
"The beta-adrenoceptor-coupled adenylate cyclase system in rat C6 glioma cells displays many characteristics observed in brain tissue: using nonlinear regression analysis of agonist competition binding curves, we demonstrated that the bulk of beta-adrenoceptors show high nanomolar affinity for isoproterenol; like in brain tissue, Gpp(NH)p does not shift agonist competition binding curves to the right; and the agonist isoproterenol rapidly downregulates the number of beta-adrenoceptors and deamplifies the norepinephrine signal." | 3.68 | The beta-adrenoceptor-coupled adenylate cyclase system in rat C6 glioma cells. Deamplification by isoproterenol and oxaprotiline. ( Bieck, PR; Duhl, DM; Gillespie, DD; Manier, DH; Sulser, F, 1992) |
"Exposure of C62B rat glioma cells to fresh medium containing fetal bovine serum induced a sensitization of the subsequent ability of isoproterenol and forskolin to stimulate cyclic AMP accumulation, compared to cells exposed to fresh medium without serum." | 3.68 | Serum-induced sensitization of cyclic AMP accumulation in C62B rat glioma cells. ( Arneson-Rotert, LJ; Hoffman, JM; Liewer, SA; Toews, ML, 1992) |
" In the present study, 2-aminopurine, which has been reported to selectively block c-fos gene expression, was used to test the hypothesis that c-fos protein might be involved in the desensitization to catecholamines was observed in 2-aminopurine-treated C6-2B rat glioma cells." | 3.68 | 2-Aminopurine inhibits RNA and protein synthesis and reduces catecholamine desensitization in C6-2B rat glioma cells. ( Brooker, G; DeBernardi, MA, 1992) |
"We used 31P-NMR spectroscopy to investigate the response of living C6 glioma cells to stimulation by a beta-adrenergic agonist, isoproterenol." | 3.68 | Beta-adrenergic stimulation of C6 glioma cells: effects of cAMP overproduction on cellular metabolites. A multinuclear NMR study. ( Canioni, P; Labouesse, J; Merle, M; Pianet, I, 1992) |
"Nano- and micromolar isoproterenol concentrations were compared by studying cyclic AMP, beta-adrenoceptor density and beta 1-adrenoceptor mRNA in rat C6 glioma cells." | 3.68 | Dose-dependent down-regulation of beta-adrenoceptors by isoproterenol in rat C6 glioma cells. ( Bieck, PR; Duhl, DM; Eiring, A; Gillespie, DD; Manier, DH; Sulser, F, 1992) |
"Cultures of rat C6 rat glioma cells exhibit a diminished response to isoproterenol and forskolin after being treated with phorbol 12,13-dibutyrate (PDbU)." | 3.68 | Regulation of cAMP levels by protein kinase C in C6 rat glioma cells. ( Bressler, JP; Tinsely, P, 1990) |
" Using [3H]DHA and unlabeled L-alprenolol, a substantial amount of over 64% specific binding of beta-adrenergic receptor has been identified on the neuroblastoma x glioma hybrid NG108-15 cell, which has been proven to display numerous functional characteristics of intact neurons." | 3.68 | Identification and characterization of the beta-adrenergic receptor on neuroblastoma x glioma hybrid NG108-15 cells. ( Cheng, KW; Ghahary, A, 1990) |
"C6 glioma cells respond to beta-adrenergic agonists (isoproterenol) with a transient rise in intracellular cyclic adenosine monophosphate level." | 3.67 | Neuroblastoma membranes inhibit isoproterenol-stimulated rise of cAMP in glioma cells. ( de Vellis, J; Wu, DK, 1984) |
"Exposure of rat glioma C6 cells to either isoproterenol or 12-O-tetradecanoylphorbol 13-acetate (TPA) resulted in desensitization of isoproterenol-stimulated adenylate cyclase activity." | 3.67 | Phorbol esters and beta-adrenergic agonists mediate desensitization of adenylate cyclase in rat glioma C6 cells by distinct mechanisms. ( Fishman, PH; Kassis, S; Patel, J; Zaremba, T, 1985) |
"Evidence is presented that isoproterenol treatment of rat C6 glioma cells, under conditions that increase glioma cell cAMP levels, causes the phosphorylative modification of several RNA polymerase II subunits." | 3.67 | Phosphorylation of rat C6 glioma cell DNA-dependent RNA polymerase II in vivo. Identification of phosphorylated subunits and modulation of phosphorylation by isoproterenol and N6,O2'-dibutyryl cyclic AMP. ( Jungmann, RA; Lee, SK; Schweppe, JS, 1984) |
"C6 glioma cells possess beta adrenergic receptors coupled with adenylate cyclase which can be irreversibly blocked by bromoacetylaminomethylpindolol (Br-AAM-pindolol), a beta adrenergic antagonist." | 3.67 | Beta adrenergic receptor repopulation of C6 glioma cells after irreversible blockade and down regulation. ( Bockaert, J; Gozlan, H; Homburger, V; Lucas, M; Pantaloni, C, 1984) |
"The activity of transglutaminase (TGase) was measured in cultured C6 glioma cells after their stimulation by either isoproterenol and isobutyl-methylxanthine or by a serum-containing medium." | 3.67 | Activation and de novo synthesis of transglutaminase in cultured glioma cells. ( Bachrach, U; Korner, G, 1985) |
"When added to intact C6 glioma cells in the micromolar range of concentrations, ADP and ATP induce an inhibition of the isoproterenol-elicited cAMP responses." | 3.67 | ADP and, indirectly, ATP are potent inhibitors of cAMP production in intact isoproterenol-stimulated C6 glioma cells. ( Labouesse, J; Merle, M; Pianet, I, 1989) |
"Competition by beta-adrenergic agonists and antagonists for 125I-pindolol binding sites on intact cells (1321N1 human astrocytoma and C62B rat glioma) was measured using short time binding assays as previously described (Toews, M." | 3.67 | Agonist-induced changes in beta-adrenergic receptors on intact cells. ( Perkins, JP; Toews, ML, 1984) |
"In C6-2B astrocytoma cells the Beta NGF content and secretion rate are increased by isoproterenol activation of beta-adrenergic receptors (Schwartz and Costa, 1977)." | 3.67 | Beta-adrenergic receptor regulation of NGF-mRNA content in rat C6-2B glioma cells. ( Costa, E; Dal Toso, R; De Bernardi, MA; Mocchetti, I, 1987) |
" This compound devoid of agonist properties, competed for all (3H)-dihydroalprenolol (3H-DHA) binding sites in C6 glioma cell and rat cerebellum membranes." | 3.67 | Irreversible blockade of beta-adrenergic receptors with a bromoacetyl derivative of pindolol. ( Bockaert, J; Bouhelal, R; Gozlan, H; Homburger, V; Lucas, M, 1985) |
"Agonist treatment of C6-glioma cells induces two altered states in beta-adrenergic receptors, a low affinity for the hydrophilic antagonist CGP-12177 and a low affinity for agonists like isoproterenol." | 3.67 | Evidence for the appearance of an uncoupled form of the beta-adrenergic receptor distinct from the internalized receptor. ( Hertel, C; Portenier, M; Staehelin, M, 1986) |
"Loss of gonadotropin receptors in murine Leydig tumor cells and of beta-adrenergic receptors in rat glioma C6 cells occurred following exposure of the cells to human chorionic gonadotropin and isoproterenol, respectively." | 3.67 | Down-regulation of gonadotropin and beta-adrenergic receptors by hormones and cyclic AMP. ( Fishman, PH; Rebois, RV; Zaremba, T, 1985) |
" Treatment of intact L6 myoblasts or C6 glioma cells with N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) inactivated beta-adrenergic receptors on membranes prepared from these cells." | 3.67 | Turnover of beta 1- and beta 2-adrenergic receptors after down-regulation or irreversible blockade. ( Molinoff, PB; Neve, KA, 1986) |
"Rat glioma C6 cells, cultured in the presence of the tricyclic antidepressant desipramine, lost a significant number of beta-adrenergic receptors in a time- and dose-dependent manner." | 3.67 | Effect of the tricyclic antidepressant desipramine on beta-adrenergic receptors in cultured rat glioma C6 cells. ( Finberg, JP; Fishman, PH, 1987) |
"When exposed to the beta-agonist (-)-isoproterenol, rat glioma C6 cells exhibited a time-and concentration-dependent reduction in isoproterenol responsiveness (desensitization) and a loss of beta-adrenergic receptors (down-regulation)." | 3.67 | Desensitization of catecholamine-stimulated adenylate cyclase and down-regulation of beta-adrenergic receptors in rat glioma C6 cells. Role of cyclic AMP and protein synthesis. ( Fishman, PH; Zaremba, TG, 1984) |
"Incubation of C6-BU1 glioma cells in the presence of isoproterenol and Ro20-1724--a potent cAMP phosphodiesterase inhibitor--results in a transient increase in intracellular cAMP levels, followed by a rapid efflux of cyclic AMP from the cells into the media." | 3.67 | Transient increase in intracellular concentration of adenosine 3':5'-cyclic monophosphate results in morphological and biochemical differentiation of C6 glioma cells in culture. ( Raj, AB; Sharma, SK, 1987) |
"The reappearance of beta-adrenergic receptors in C6-glioma cells after desensitization with isoproterenol was studied using the antagonist [3H]CGP-12177." | 3.66 | Reappearance of beta-adrenergic receptors after isoproterenol treatment in intact C6-cells. ( Hertel, C; Staehelin, M, 1983) |
" The beta-adrenergic receptors of cultured rat C6 glioma cells (2B clone) as assessed by [(125)I]iodohydroxybenzylpindolol binding were decreased 50 and >95% after pretreatment with 8 nM and 1 muM aminobenzylpropranolol, respectively." | 3.66 | Quantitative relationship between beta-adrenergic receptor number and physiologic responses as studied with a long-lasting beta-adrenergic antagonist. ( Brooker, G; Linden, J; Terasaki, WL, 1979) |
" In two cell lines, C6 glioma and WEHI 7 lymphoma cells, -50% of the cell surface receptors disappear within minutes of incubation of the cells with isoproterenol." | 3.66 | Rapid and reversible disappearance of beta-adrenergic cell surface receptors. ( Simons, P; Staehelin, M, 1982) |
" Cultured rat glioma C-6 cells, with beta-adrenergic receptors, and human lung WI-38 cells, with prostaglandin receptors, were exposed to catecholamine (isoproterenol) and prostaglandin E1, respectively, while their junctions were probed with microinjected fluorescent-labelled mono-, di-, and triglutamate." | 3.66 | Hormonal regulation of cell junction permeability: upregulation by catecholamine and prostaglandin E1. ( Dahl, G; Loewenstein, WR; Radu, A, 1982) |
"The beta-adrenergic receptor of C6 glioma cells contains a disulfide bridge which can be reduced by dithiothreitol (DTT)." | 3.66 | Irreversible inactivation of beta-adrenergic receptors of C6 glioma cells. Synthesis and study of a thiol derivative of propranolol. ( Bockaert, J; Gozlan, H; Homburger, V; Lucas, M; Michelot, R, 1980) |
"The mechanism of isoproterenol and N6,O2-dibutyryl adenosine 3':5'-monophosphate (dibutyryl cAMP) induction of lactate dehydrogenase A subunit mRNA (mRNALDH) was investigated in the rat C6 glioma cell line." | 3.66 | Cyclic AMP regulation of lactate dehydrogenase. Isoproterenol and N6,O2-dibutyryl cyclic amp increase the rate of transcription and change the stability of lactate dehydrogenase a subunit messenger RNA in rat C6 glioma cells. ( Jungmann, RA; Kelley, DC; Miles, MF; Milkowski, DM, 1983) |
"17) activity has been studied by using as a model the isoproterenol stimulation of cyclic AMP phosphodiesterase activity in C6 glioma cells." | 3.66 | Regulation by a beta-adrenergic receptor of a Ca2+-independent adenosine 3',5'-(cyclic)monophosphate phosphodiesterase in C6 glioma cells. ( Costa, E; Hanbauer, I; Onali, P; Schwartz, JP, 1981) |
"Persistent stimulation with isoproterenol of the beta adrenergic receptor located in C6 glioma cell membranes results in a rapid rise in the cyclic AMP content, an activation of soluble cyclic AMP-dependent protein kinase, a translocation of catalytic subunits of the activated protein kinase to the nucleus and a delayed (3--4 hr later) increase of cyclic AMP phosphodiesterase activity and beta-nerve growth factor content." | 3.66 | beta Adrenergic receptor-mediated regulation of cyclic nucleotide phosphodiesterase in C6 glioma cells: vinblastine blockade of isoproterenol induction. ( Costa, E; Schwartz, JP, 1980) |
"Incubation of C6 glioma cells with isoproterenol elicits an increase in cyclic AMP content, followed by an activation of cyclic AMP-dependent protein kinase (ATP:protein phosphotransferase, EC 2." | 3.66 | Protein kinase translocation following beta-adrenergic receptor activation in C6 glioma cells. ( Costa, E; Schwartz, JP, 1980) |
" In the present study, however, changes in intracellular cyclic AMP level in several lines of cultured cells (normal 3T3 and SV40 and polyomavirus-transformed 3T3 cells; 3T6, C6 GLIOMA, MOUSE L, and Novikoff rat hepatoma cells) by treatment with papaverine, prostaglandine E1 or isoproterenol did not correlate with the inhibition of the uridine, hypoxanthine or deoxyglucose transport rates by these chemicals." | 3.65 | Cyclic AMP, membrane transport and cell division. I. Effects of various chemicals on cyclic AMP levels and rate of transport of neucleosides, hypoxanthine and deoxyglucose in several lines of cultured cells. ( Plagemann, PG; Sheppard, JR, 1975) |
" When C6 glioma cells were incubated with mycophenolic acid, a potent and specific inhibitor of IMP:NAD oxidoreductase (EC 1." | 3.65 | Reduction in beta-adrenergic response of cultured glioma cells following depletion of intracellular GTP. ( Franklin, TJ; Twose, PA, 1977) |
" Each antagonist alone caused smaller shifts to the right in the dose-response curve to NE and, when present simultaneously, completely abolished the NE response." | 1.29 | Inducible expression of beta 1- and beta 2-adrenergic receptors in rat C6 glioma cells: functional interactions between closely related subtypes. ( Esbenshade, TA; Guerrero, SW; Minneman, KP; Zhong, H, 1996) |
"Isoproterenol treatment of C6 cells altered beta 1 AR mRNA levels in a biphasic manner; i." | 1.29 | Agonist and cyclic AMP-mediated regulation of beta 1-adrenergic receptor mRNA and gene transcription in rat C6 glioma cells. ( Duman, RS; Feussner, GK; Fishman, PH; Hosoda, K; Rydelek-Fitzgerald, L, 1994) |
"Chronic in vitro treatment of C6 glioma cells with idazoxan did not significantly affect cholera or pertussis toxin catalyzed ribosylation of Gs and Gi/Go in these cells." | 1.28 | Idazoxan down-regulates beta-adrenoceptors on C6 glioma cells in vitro. ( Bitran, JA; Chen, G; Gusovsky, F; Manji, HK; Potter, WZ, 1992) |
"Pre-treatment with isoproterenol or the cyclic AMP analogue, dibutyryl cyclic AMP, induced refractoriness to forskolin." | 1.27 | Forskolin-stimulated cyclic AMP accumulation mediates protein synthesis-dependent refractoriness in C6-2B rat glioma cells. ( Barovsky, K; Brooker, G; Pedone, C, 1983) |
"Rat C 6 glioma is known to possess a beta-adrenergic receptor with which intracellular cyclic adenosine monophosphate (cAMP) levels are altered to control cell growth in vitro." | 1.27 | [Treatment of rat glioma with a beta-adrenergic agonist and a phosphodiesterase inhibitor in vivo]. ( Egawa, T; Hayakawa, T; Mogami, H; Sakamoto, Y; Shimizu, K; Ushio, Y; Yoshida, T, 1987) |
" Computer-assisted analysis of dose-response curves resulting from the inhibition of the binding of [125I]iodopindolol by the beta-1 and beta-2 selective compounds ICI 89,406 and ICI 118,551 revealed that approximately one-third of the beta adrenergic receptors on these cells were beta-1 receptors." | 1.27 | Selective regulation of beta-1 and beta-2 adrenergic receptors by atypical agonists. ( Barrett, DA; Molinoff, PB; Neve, KA, 1985) |
"Isoprenaline treatment of C6-glioma cells induced a fast decrease in the number of beta-adrenergic receptors as determined by binding of [3H]CGP-12177, which paralleled the decrease in the hormonally stimulated adenylate cyclase activity." | 1.27 | Determination of the desensitization of beta-adrenergic receptors by [3H]CGP-12177. ( Hertel, C; Müller, P; Portenier, M; Staehelin, M, 1983) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 89 (56.69) | 18.7374 |
1990's | 53 (33.76) | 18.2507 |
2000's | 12 (7.64) | 29.6817 |
2010's | 3 (1.91) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Adejare, A | 1 |
Nie, JY | 1 |
Hebel, D | 1 |
Brackett, LE | 1 |
Choi, O | 1 |
Gusovsky, F | 2 |
Padgett, WL | 1 |
Daly, JW | 1 |
Creveling, CR | 1 |
Kirk, KL | 1 |
Wnorowski, A | 1 |
Such, J | 1 |
Paul, RK | 1 |
Wersto, RP | 1 |
Indig, FE | 1 |
Jozwiak, K | 1 |
Bernier, M | 1 |
Wainer, IW | 1 |
Malchinkhuu, E | 1 |
Sato, K | 1 |
Maehama, T | 1 |
Ishiuchi, S | 1 |
Yoshimoto, Y | 1 |
Mogi, C | 1 |
Kimura, T | 1 |
Kurose, H | 1 |
Tomura, H | 1 |
Okajima, F | 1 |
Aerts, I | 1 |
Grobben, B | 3 |
Van Ostade, X | 1 |
Slegers, H | 3 |
Obara, Y | 1 |
Yanagihata, Y | 1 |
Abe, T | 1 |
Dafik, L | 1 |
Ishii, K | 1 |
Nakahata, N | 1 |
Higashida, H | 3 |
Hossain, KZ | 1 |
Takahagi, H | 1 |
Noda, M | 1 |
Ribas, C | 1 |
Takesono, A | 1 |
Sato, M | 1 |
Hildebrandt, JD | 1 |
Lanier, SM | 1 |
Morita, K | 1 |
Arimochi, H | 1 |
Itoh, H | 1 |
Her, S | 1 |
Sokolowska, P | 1 |
Nowak, JZ | 1 |
Tas, PW | 2 |
Gambaryan, S | 1 |
Roewer, N | 1 |
Chang, YJ | 1 |
Kim, YL | 1 |
Jo, JY | 1 |
Kyeok, K | 1 |
Kim, HL | 1 |
Im, DS | 1 |
Kassis, S | 3 |
Fishman, PH | 11 |
Lee, SK | 1 |
Schweppe, JS | 4 |
Jungmann, RA | 8 |
Homburger, V | 6 |
Pantaloni, C | 1 |
Lucas, M | 7 |
Gozlan, H | 4 |
Bockaert, J | 7 |
Hertel, C | 6 |
Affolter, H | 1 |
Portenier, M | 4 |
Staehelin, M | 7 |
Müller, P | 2 |
Browning, ET | 1 |
Nicklas, WJ | 1 |
Toews, ML | 3 |
Perkins, JP | 3 |
Koschel, K | 3 |
Derda, DF | 2 |
Miles, MF | 4 |
Barovsky, K | 1 |
Pedone, C | 1 |
Brooker, G | 5 |
Zaremba, TG | 1 |
Schwartz, JP | 8 |
Costa, E | 5 |
Michelot, R | 1 |
Arenander, AT | 1 |
de Vellis, J | 3 |
Cantau, B | 1 |
Barabe, J | 1 |
Penit, J | 2 |
Chelmicka-Schorr, E | 2 |
Arnason, BG | 2 |
Holshouser, SJ | 1 |
Onali, P | 2 |
Hanbauer, I | 1 |
Hung, P | 1 |
Dibner, MD | 1 |
Insel, PA | 1 |
Mallorga, P | 2 |
Tallman, JF | 2 |
Katada, T | 1 |
Amano, T | 1 |
Ui, M | 1 |
Miki, N | 1 |
Tanaka, T | 1 |
Kato, K | 2 |
Nakano, T | 1 |
Nagatsu, T | 1 |
Kano-Tanaka, K | 1 |
Harrison, JJ | 2 |
Schwoch, G | 1 |
Shitara, N | 2 |
McKeever, PE | 2 |
Cummins, C | 1 |
Smith, BH | 2 |
Kornblith, PL | 2 |
Hirata, F | 1 |
Kelley, DC | 2 |
Milkowski, DM | 1 |
Milkowski, D | 1 |
Radu, A | 1 |
Dahl, G | 1 |
Loewenstein, WR | 1 |
Frederich, RC | 1 |
Waldo, GL | 1 |
Harden, TK | 2 |
Wu, DK | 1 |
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Sportiello, MG | 1 |
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Nakamura, H | 1 |
Fujiwara, M | 1 |
Simons, P | 1 |
Hashimoto, S | 1 |
Guroff, G | 1 |
Lee, S | 1 |
Suter, P | 1 |
Suter, S | 1 |
Sernia, C | 1 |
Thomas, WG | 1 |
Ye, P | 2 |
Laszkiewicz, I | 2 |
Wiggins, RC | 2 |
Konat, GW | 1 |
Tamir, M | 1 |
Kushner, L | 1 |
Adie, EJ | 1 |
Milligan, G | 3 |
Miller, T | 1 |
Curran, PK | 2 |
Feussner, GK | 2 |
Chen, J | 1 |
Rasenick, MM | 3 |
Hough, C | 2 |
Fukamauchi, F | 1 |
Chuang, DM | 3 |
Hosoda, K | 1 |
Rydelek-Fitzgerald, L | 1 |
Duman, RS | 2 |
Kim, GD | 2 |
Kreps, DM | 1 |
Whittle, SM | 1 |
Hoffman, JM | 2 |
Boyer, JL | 1 |
Lazarowski, ER | 1 |
Chen, XH | 1 |
Papadopoulos, V | 1 |
Guarneri, P | 1 |
Lin, WW | 1 |
Levi, G | 1 |
Patrizio, M | 1 |
Bernardo, A | 1 |
Petrucci, TC | 1 |
Agresti, C | 1 |
Debernardi, MA | 3 |
Munshi, R | 1 |
Orlandi, PA | 1 |
Watanabe, M | 1 |
Saito, T | 1 |
McCrea, KE | 1 |
Hill, SJ | 1 |
Streich, S | 1 |
Brüss, M | 1 |
Bönisch, H | 1 |
Zhong, H | 2 |
Guerrero, SW | 2 |
Esbenshade, TA | 1 |
Minneman, KP | 2 |
Colangelo, AM | 1 |
Pani, L | 1 |
Mocchetti, I | 2 |
Fitzgerald, LR | 1 |
Li, Z | 1 |
Machida, CA | 2 |
Hoffman, J | 1 |
Whittle, S | 1 |
Toews, M | 1 |
MacEwan, DJ | 1 |
Kurino, M | 1 |
Fukunaga, K | 1 |
Ushio, Y | 2 |
Miyamoto, E | 1 |
Canova, C | 1 |
Baudet, C | 1 |
Chevalier, G | 1 |
Brachet, P | 1 |
Wion, D | 1 |
Schömig, E | 1 |
Russ, H | 1 |
Staudt, K | 1 |
Martel, F | 1 |
Gliese, M | 1 |
Gründemann, D | 1 |
Martín, M | 1 |
Albasanz, JL | 1 |
Fernández, M | 1 |
Ros, M | 1 |
Zumwalt, JW | 1 |
Thunstrom, BJ | 1 |
Spangelo, BL | 1 |
Bergström, D | 1 |
Jacobsson, SO | 1 |
Fowler, CJ | 1 |
Storm, SM | 1 |
Khawaja, XZ | 1 |
Yang, X | 1 |
Wand, G | 1 |
Slamon, ND | 1 |
Pentreath, VW | 1 |
Roymans, D | 2 |
Willems, R | 1 |
Vissenberg, K | 1 |
De Jonghe, C | 1 |
Claes, P | 2 |
Lascu, I | 1 |
Van Bockstaele, D | 1 |
Verbelen, JP | 1 |
Van Broeckhoven, C | 1 |
Kirigiti, P | 1 |
Bai, Y | 1 |
Yang, YF | 1 |
Li, X | 1 |
Li, B | 1 |
Brewer, G | 1 |
Schmitt, H | 1 |
Pochet, R | 1 |
Franklin, TJ | 3 |
Twose, PA | 3 |
McCarthy, KD | 1 |
Terasaki, WL | 1 |
Linden, J | 1 |
Sheppard, JR | 1 |
Plagemann, PG | 1 |
Traber, J | 1 |
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Fischer, K | 1 |
Hamprecht, B | 1 |
Bachrach, U | 3 |
Edström, A | 1 |
Kanje, M | 2 |
Löfgren, P | 1 |
Walum, E | 1 |
Venter, BR | 1 |
Venter, JC | 2 |
Kaplan, NO | 2 |
Halbach, M | 1 |
Lazarewicz, JW | 1 |
Sellström, A | 1 |
Hamberger, A | 1 |
Yin, J | 1 |
Howells, RD | 1 |
Bieck, PR | 2 |
Duhl, DM | 2 |
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Gillespie, DD | 2 |
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Labouesse, J | 5 |
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Konat, G | 1 |
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1 review available for isoproterenol and Glioma
Article | Year |
---|---|
Agonist regulation of cellular levels of the stimulatory guanine nucleotide-binding protein, Gs, in wild type and transfected neuroblastoma-glioma hybrid NG108-15 cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Down-Regulation; Glioma; GTP-Binding Proteins | 1993 |
156 other studies available for isoproterenol and Glioma
Article | Year |
---|---|
Effect of fluorine substitution on the adrenergic properties of 3-(tert-butylamino)-1-(3,4-dihydroxyphenoxy)-2-propanol.
Topics: Adrenergic beta-Agonists; Animals; Cell Membrane; Cerebral Cortex; Chemical Phenomena; Chemistry; Cy | 1991 |
Concurrent activation of β
Topics: Animals; Apoptosis; Brain Neoplasms; Carcinogenesis; Cell Cycle; Cell Line, Tumor; Cell Movement; Ce | 2017 |
Role of Rap1B and tumor suppressor PTEN in the negative regulation of lysophosphatidic acid--induced migration by isoproterenol in glioma cells.
Topics: Cell Movement; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Glioma; Humans; | 2009 |
Cyclic AMP-dependent down regulation of ecto-nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) in rat C6 glioma.
Topics: Animals; Bucladesine; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Down-Regulation | 2011 |
Gα(h)/transglutaminase-2 activity is required for maximal activation of adenylylcyclase 8 in human and rat glioma cells.
Topics: Adenylyl Cyclases; Amino Acid Substitution; Animals; Cell Line, Tumor; Colforsin; Cyclic AMP; Enzyme | 2013 |
Measurement of adenylyl cyclase by separating cyclic AMP on silica gel thin-layer chromatography.
Topics: Adenylyl Cyclases; Animals; Autoradiography; Cholera Toxin; Chromatography, Thin Layer; Cyclic AMP; | 2002 |
Pertussis toxin-insensitive activation of the heterotrimeric G-proteins Gi/Go by the NG108-15 G-protein activator.
Topics: Animals; Brain; Carrier Proteins; Cattle; Cell Line; Cell Membrane; Colforsin; Glioma; GTP-Binding P | 2002 |
Possible involvement of 5alpha-reduced neurosteroids in adrenergic and serotonergic stimulation of GFAP gene expression in rat C6 glioma cells.
Topics: 20-alpha-Dihydroprogesterone; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adrenergic beta-Agonists; Analy | 2006 |
Cyclic AMP formation in C6 glioma cells: effect of PACAP and VIP in early and late passages.
Topics: Animals; Cell Line, Tumor; Cellular Senescence; Colforsin; Cyclic AMP; Glioma; Isoproterenol; Pituit | 2006 |
Volatile anesthetics affect the morphology of rat glioma C6 cells via RhoA, ERK, and Akt activation.
Topics: Adrenergic beta-Agonists; Amides; Anesthetics, Inhalation; Animals; Cell Line, Tumor; Cell Shape; Cu | 2007 |
Dioleoyl phosphatidic acid induces morphological changes through an endogenous LPA receptor in C6 glioma cells.
Topics: Animals; Cell Line, Tumor; Cell Survival; Cytotoxins; Drug Partial Agonism; Glioma; Isoproterenol; I | 2008 |
Functional alteration of the beta-adrenergic receptor during desensitization of mammalian adenylate cyclase by beta-agonists.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Drug Tolerance; Friend murine leukemia virus; | 1984 |
Phosphorylation of rat C6 glioma cell DNA-dependent RNA polymerase II in vivo. Identification of phosphorylated subunits and modulation of phosphorylation by isoproterenol and N6,O2'-dibutyryl cyclic AMP.
Topics: Amino Acids; Animals; Bucladesine; Cell Line; Electrophoresis, Polyacrylamide Gel; Glioma; Isoproter | 1984 |
Beta adrenergic receptor repopulation of C6 glioma cells after irreversible blockade and down regulation.
Topics: Cells, Cultured; Cycloheximide; Glioma; Isoproterenol; Nerve Block; Pindolol; Receptors, Adrenergic, | 1984 |
Desensitized beta-adrenoceptors of C6-glioma cells have distinct binding properties.
Topics: Animals; Cell Line; Cell Membrane; Glioma; Guanosine Triphosphate; Isoproterenol; Rats; Receptors, A | 1984 |
Some unique properties of CGP-12177.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cyclic AMP; Digitonin; Dihydroalprenolol; Glioma; Isoproteren | 1984 |
Induction of glutamine synthetase by dibutyryl cyclic AMP in C-6 glioma cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Cell Division; Cell Line; Cyclic AMP; | 1982 |
Turn on and turn off reactions of beta-adrenergic-sensitive adenylate cyclase in control and desensitized C6 glioma cells.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cell Line; Dihydroalprenolol; Enzyme Activatio | 1982 |
Reappearance of beta-adrenergic receptors after isoproterenol treatment in intact C6-cells.
Topics: Adrenergic beta-Antagonists; Animals; Cations; Cell Line; Cycloheximide; Glioma; Isoproterenol; Kine | 1983 |
Determination of the desensitization of beta-adrenergic receptors by [3H]CGP-12177.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Binding Sites; Binding, Competitive; Cell Line; Cell | 1983 |
Agonist-induced changes in beta-adrenergic receptors on intact cells.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Astrocytoma; Binding, Competitive; C | 1984 |
A hormone-independent rise of adenosine 3',5'-monophosphate desensitizes coupling of beta-adrenergic receptors to adenylate cyclase in rat glioma C6-cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Carrier Proteins; Cholera Toxin; Cyclic AMP | 1980 |
Cyclic AMP regulation of lactate dehydrogenase. Isoproterenol and N6,O2'-dibutyryl cyclic AMP increase the levels of lactate dehydrogenase-5 isozyme and its messenger RNA in rat C6 glioma cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cell Line; Cyclic AMP; Dactinomycin; Glioma; Half | 1980 |
Forskolin-stimulated cyclic AMP accumulation mediates protein synthesis-dependent refractoriness in C6-2B rat glioma cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Cyclohexi | 1983 |
Desensitization of catecholamine-stimulated adenylate cyclase and down-regulation of beta-adrenergic receptors in rat glioma C6 cells. Role of cyclic AMP and protein synthesis.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Bucladesine; Cell Line; Cell Membrane; Chol | 1984 |
Protein kinase translocation following beta-adrenergic receptor activation in C6 glioma cells.
Topics: Animals; Cell Line; Cyclic AMP; Cytosol; Glioma; Isoproterenol; Kinetics; Protamine Kinase; Protein | 1980 |
beta Adrenergic receptor-mediated regulation of cyclic nucleotide phosphodiesterase in C6 glioma cells: vinblastine blockade of isoproterenol induction.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cell Line; Cyclic AMP; Enzyme Induction; Glioma; Isopr | 1980 |
Irreversible inactivation of beta-adrenergic receptors of C6 glioma cells. Synthesis and study of a thiol derivative of propranolol.
Topics: Adenylyl Cyclases; Animals; Cell Line; Dithiothreitol; Ethylmaleimide; Glioma; Isoproterenol; Kineti | 1980 |
Glial-released proteins in clonal cultures and their modulation by hydrocortisone.
Topics: Animals; Bucladesine; Cell Line; Estradiol; Glioma; Hydrocortisone; Isoproterenol; Melatonin; Molecu | 1980 |
Further evidence that desensitization of beta-adrenergic-sensitive adenylate cyclase proceeds in two steps. Modification of the coupling and loss of beta-adrenergic receptors.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cycloheximide; Dihydroalprenolol; Enzyme Activation; Glioma; | 1980 |
C-6 glioma growth in rats: suppression with a beta-adrenergic agonist and a phosphodiesterase inhibitor.
Topics: Animals; Brain Neoplasms; Cell Line; Cyclic AMP; Drug Therapy, Combination; Glioma; Humans; Isoprote | 1980 |
Regulation by a beta-adrenergic receptor of a Ca2+-independent adenosine 3',5'-(cyclic)monophosphate phosphodiesterase in C6 glioma cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; 8-Bromo Cyclic Adenosine M | 1981 |
Cyclic AMP regulation of lactate dehydrogenase. Quantitation of lactate dehydrogenase M-subunit messenger RNA in isoproterenol-and N6,O2'-dibutyryl cyclic AMP-stimulated rat C6 glioma cells by hybridization analysis using a cloned cDNA probe.
Topics: Animals; Bucladesine; Cell Line; Cloning, Molecular; Cyclic AMP; DNA Restriction Enzymes; DNA, Recom | 1981 |
Growth of C6 glioma cells in serum-containing medium decreases beta-adrenergic receptor number.
Topics: Animals; Blood; Cell Line; Cell Separation; Culture Media; Cyclic AMP; Glioma; Isoproterenol; Rats; | 1981 |
Catecholamine-induced desensitization of adenylate cyclase in rat glioma C6 cells. Evidence for a specific uncoupling of beta-adrenergic receptors from a functional regulatory component of adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Catecholamines; Cells, Cultured; Cholera Toxin; Dihydroalprenolol; Gliom | 1981 |
Differences in the beta-adrenergic responsiveness between high and low passage rat glioma C6 cells.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Cholera Toxin; Cyclic AMP; Dihydroalprenolol; | 1981 |
RNA polymerase II in C6 glioma cells. Alpha-amanitin blockade of cAMP phosphodiesterase induction by beta-adrenergic stimulation.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Amanitins; Animals; Cell Line; Cell Nucleus; Cyclic AMP; Dactin | 1982 |
Modulation by islet-activating protein of adenylate cyclase activity in C6 glioma cells.
Topics: Adenine Nucleotides; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Bacterial Proteins; Calciu | 1982 |
Receptor-associated changes of the catecholamine-sensitive adenylate cyclase in glioma cells doubly transformed with Moloney sarcoma virus.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cell Transf | 1982 |
Photoaffinity labelling of beta-adrenergic receptors of C6 glioma cells. Presence of a nucleophilic group in the receptor.
Topics: Adenylyl Cyclases; Affinity Labels; Animals; Cell Membrane; Cells, Cultured; Darkness; Glioma; Isopr | 1982 |
Phosphorylative modification of histone H1 subspecies following isoproterenol and N6,O2'-dibutyryl cyclic AMP stimulation of rat C6 glioma cells.
Topics: Amino Acids; Animals; Bucladesine; Cell Line; Cyclic AMP; Glioma; Histones; Isoproterenol; Neoplasms | 1982 |
beta-Adrenergic receptor desensitization stimulates glucose uptake in C6 rat glioma cells.
Topics: Animals; Biological Transport, Active; Cell Line; Cyclic AMP; Deoxy Sugars; Deoxyglucose; Epinephrin | 1982 |
Cyclic AMP regulation of lactate dehydrogenase. Isoproterenol and N6,O2-dibutyryl cyclic amp increase the rate of transcription and change the stability of lactate dehydrogenase a subunit messenger RNA in rat C6 glioma cells.
Topics: Animals; Bucladesine; Cell Line; Cyclic AMP; Glioma; Isoproterenol; L-Lactate Dehydrogenase; Rats; R | 1983 |
Regulation of lactate dehydrogenase gene expression.
Topics: Animals; Cell Line; Cyclic AMP; Genes; Glioma; Isoenzymes; Isoproterenol; Kinetics; L-Lactate Dehydr | 1983 |
Hormonal regulation of cell junction permeability: upregulation by catecholamine and prostaglandin E1.
Topics: Alprostadil; Animals; Cell Communication; Cell Membrane Permeability; Cells, Cultured; Cyclic AMP; G | 1982 |
Characterization of agonist-induced beta-adrenergic receptor-specific desensitization in C62B glioma cells.
Topics: Adenylyl Cyclases; Animals; Astrocytoma; Catecholamines; Cells, Cultured; Centrifugation, Density Gr | 1983 |
Evidence for intravesicular beta-adrenergic receptors in membrane fractions from desensitized cells: binding of the hydrophilic ligand CGP-12177 only in the presence of alamethicin.
Topics: Alamethicin; Animals; Anti-Bacterial Agents; Cells, Cultured; Centrifugation, Density Gradient; Glio | 1983 |
Neuroblastoma membranes inhibit isoproterenol-stimulated rise of cAMP in glioma cells.
Topics: Animals; Cell Fractionation; Cell Membrane; Cells, Cultured; Cyclic AMP; Glioma; Isoproterenol; Neur | 1984 |
Cytoskeletal structures and oligodendroglial differentiation in C-6 glial cells.
Topics: 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase; 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; B | 1984 |
Response of C-6 glioma to isoproterenol and papaverine in vivo depends on beta-adrenergic receptor density.
Topics: Animals; Cells, Cultured; Glioma; In Vitro Techniques; Isoproterenol; Neoplasm Transplantation; Neop | 1984 |
The beta-adrenergic receptor system in human glioma-derived cell lines: the mode of phosphodiesterase induction and the macromolecules phosphorylated by cyclic AMP-dependent protein kinase.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Cell Line; Cyclic AMP; Cytosol; Dih | 1984 |
Rapid and reversible disappearance of beta-adrenergic cell surface receptors.
Topics: Animals; Cell Line; Endocytosis; Glioma; Isoproterenol; Lymphoma; Propanolamines; Receptors, Adrener | 1982 |
Beta-adrenergic receptor regulation of a cyclic AMP phosphodiesterase in C6 glioma cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Amanitins; Animals; Cell Line; Cyclic AMP; D | 1984 |
Norepinephrine and nerve growth factor: similar proteins phosphorylated in the nuclei of target cells.
Topics: Animals; Cell Line; Chromosomal Proteins, Non-Histone; Ganglia, Sympathetic; Glioma; Isoproterenol; | 1982 |
Isoproterenol-induced selective phosphorylation in vivo of the 214,000 dalton subunit of rat C6 glioma cell RNA polymerase II.
Topics: Animals; Cell Line; DNA-Directed RNA Polymerases; Glioma; Isoproterenol; Macromolecular Substances; | 1981 |
Isoproterenol-induced selective phosphorylative modification in vivo of rat C6 glioma cell histones.
Topics: Animals; Cell Line; Glioma; Histones; Isoproterenol; Neoplasm Proteins; Neoplasms, Experimental; Pho | 1980 |
A novel inhibitory role for glucocorticoids in the secretion of angiotensinogen by C6 glioma cells.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Angiotensinogen; Animals; Bucladesine; Cyclic AMP; Dexamet | 1994 |
Transcriptional regulation of myelin associated glycoprotein gene expression by cyclic AMP.
Topics: Animals; Blotting, Northern; Choline O-Acetyltransferase; Cyclic AMP; DNA, Complementary; Gene Expre | 1994 |
Expression of functional delta opioid receptors in Xenopus oocytes.
Topics: Adenylyl Cyclases; Analgesics; Analysis of Variance; Animals; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4 | 1993 |
Independent and coordinate regulation of beta 1- and beta 2-adrenergic receptors in rat C6 glioma cells.
Topics: Animals; Astrocytes; Cell Differentiation; Cholera Toxin; Colforsin; Cyclic AMP; Down-Regulation; Gl | 1994 |
Chronic treatment of C6 glioma cells with antidepressant drugs increases functional coupling between a G protein (Gs) and adenylyl cyclase.
Topics: Adenylyl Cyclases; Animals; Antidepressive Agents; Cell Membrane; Cytosol; Desipramine; Dose-Respons | 1995 |
Regulation of beta-adrenergic receptor mRNA in rat C6 glioma cells is sensitive to the state of microtubule assembly.
Topics: Animals; Binding Sites; Colchicine; Cyclic AMP; Dose-Response Relationship, Drug; Down-Regulation; G | 1994 |
Agonist and cyclic AMP-mediated regulation of beta 1-adrenergic receptor mRNA and gene transcription in rat C6 glioma cells.
Topics: Adrenergic beta-1 Receptor Agonists; Animals; Colforsin; Cyclic AMP; Down-Regulation; Endotoxins; Gl | 1994 |
Receptor availability defines the extent of agonist-mediated G-protein down-regulation in neuroblastoma x glioma hybrid cells transfected to express the beta 2-adrenoceptor.
Topics: Adenylyl Cyclases; Adrenergic beta-2 Receptor Antagonists; Alprenolol; Down-Regulation; Gene Express | 1994 |
Lysophosphatidic acid mimics serum-induced sensitization of cyclic AMP accumulation.
Topics: Alprostadil; Animals; Astrocytoma; Blood; Colforsin; Cyclic AMP; Drug Interactions; Glioma; Humans; | 1993 |
Identification of a P2Y-purinergic receptor that inhibits adenylyl cyclase.
Topics: Adenylyl Cyclase Inhibitors; Animals; Cyclic AMP; Enzyme Activation; Glioma; Isoproterenol; Kinetics | 1993 |
Regulation of C6 glioma cell steroidogenesis by adenosine 3',5'-cyclic monophosphate.
Topics: Adenylyl Cyclases; Aminoglutethimide; Animals; Cyclic AMP; Glioma; Humans; Isoproterenol; Mevalonic | 1994 |
Endothelin- and ATP-induced inhibition of adenylyl cyclase activity in C6 glioma cells: role of Gi and calcium.
Topics: Adenosine Triphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Calcimycin; C | 1993 |
Human immunodeficiency virus coat protein gp120 inhibits the beta-adrenergic regulation of astroglial and microglial functions.
Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Cerebral Cortex; Clonidin | 1993 |
Ca2+ inhibition of beta-adrenergic receptor- and forskolin-stimulated cAMP accumulation in C6-2B rat glioma cells is independent of protein kinase C.
Topics: Animals; Calcium; Colforsin; Cyclic AMP; Enzyme Activation; Glioma; Hydrolysis; Isoproterenol; Phosp | 1993 |
Brefeldin A blocks the response of cultured cells to cholera toxin. Implications for intracellular trafficking in toxin action.
Topics: Adenocarcinoma; Adenylyl Cyclases; Animals; Biological Transport; Brefeldin A; Cell Line; Chloroquin | 1993 |
[Effects of tubulin on beta adrenergic receptor linked to adenylyl cyclase system].
Topics: Adenylyl Cyclases; Animals; Cell Membrane Permeability; Cells, Cultured; Glioma; GTP-Binding Protein | 1993 |
Comparison of duration of agonist action at beta 1- and beta 2- adrenoceptors in C6 glioma cells: evidence that the long duration of action of salmeterol is specific to the beta 2-adrenoceptor.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; | 1996 |
Expression of the extraneuronal monoamine transporter (uptake2) in human glioma cells.
Topics: 1-Methyl-4-phenylpyridinium; Amines; Anti-Inflammatory Agents; Barium; Binding, Competitive; Cortico | 1996 |
Inducible expression of beta 1- and beta 2-adrenergic receptors in rat C6 glioma cells: functional interactions between closely related subtypes.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Colforsin; Cyclic AMP; Epinephrine; | 1996 |
Correlation between increased AP-1NGF binding activity and induction of nerve growth factor transcription by multiple signal transduction pathways in C6-2B glioma cells.
Topics: Animals; Base Sequence; Cell Line; Cell Nucleus; Enzyme Inhibitors; Fibroblast Growth Factor 2; Glio | 1996 |
Adrenergic regulation of ICER (inducible cyclic AMP early repressor) and beta1-adrenergic receptor gene expression in C6 glioma cells.
Topics: Animals; Base Sequence; Binding Sites; Cyclic AMP Response Element Modulator; DNA Primers; DNA-Bindi | 1996 |
Modulation of cyclic AMP accumulation in glial cells by exogenous phospholipase C.
Topics: Adenylate Cyclase Toxin; Astrocytoma; Colforsin; Cyclic AMP; Down-Regulation; Glioma; Humans; Isopro | 1996 |
Agonist regulation of adenylate cyclase activity in neuroblastoma x glioma hybrid NG108-15 cells transfected to co-express adenylate cyclase type II and the beta 2-adrenoceptor. Evidence that adenylate cyclase is the limiting component for receptor-mediat
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Amino Acid Sequence; Base Sequence; DNA Primers; DNA, C | 1996 |
Selective desensitization of beta 1- and beta 2-andrenergic receptors in C6 glioma cells. Effects on catecholamine responsiveness.
Topics: Adrenergic beta-Agonists; Animals; Cell Membrane; Cyclic AMP; Dexamethasone; Epinephrine; Glioma; Gl | 1995 |
Cyclic AMP inhibits activation of mitogen-activated protein kinase and cell proliferation in response to growth factors in cultured rat cortical astrocytes.
Topics: Adrenergic beta-Agonists; Animals; Astrocytes; Calcium-Calmodulin-Dependent Protein Kinases; Cell Di | 1996 |
Noradrenaline inhibits the programmed cell death induced by 1,25-dihydroxyvitamin D3 in glioma.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Apoptosis; Brain Neoplasms; Calcitri | 1997 |
The extraneuronal monoamine transporter exists in human central nervous system glia.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Astrocytes; Biological Transport; Cells, Cultured; Cerebral Co | 1998 |
Cross-talk between beta-adrenergic and metabotropic glutamate receptors in rat C6 glioma cells.
Topics: Adrenergic beta-Agonists; Animals; Cell Membrane; Enzyme Activation; Glioma; Glutamic Acid; Isoenzym | 1998 |
Interleukin-1beta and catecholamines synergistically stimulate interleukin-6 release from rat C6 glioma cells in vitro: a potential role for lysophosphatidylcholine.
Topics: Adrenergic beta-Agonists; Animals; Catecholamines; Cyclic AMP; Drug Synergism; Glioma; Interleukin-1 | 1999 |
The effect of hydrogen peroxide upon beta-adrenoceptor density and function in C6 rat glioma cells.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cell Death; Colforsin; Culture Media, Serum-Fr | 1999 |
Probing for drug-induced multiplex signal transduction pathways using high resolution two-dimensional gel electrophoresis: application to beta-adrenoceptor stimulation in the rat C6 glioma cell.
Topics: Animals; Brain Neoplasms; Cyclic AMP; Electrophoresis, Gel, Two-Dimensional; Glioma; Isoproterenol; | 1999 |
Ethanol uses cAMP-independent signal transduction mechanisms to activate proenkephalin promoter activity in rat C6 glioma cells.
Topics: Adrenergic beta-Agonists; Animals; Central Nervous System Depressants; Choline O-Acetyltransferase; | 2000 |
Antioxidant defense against antidepressants in C6 and 1321N1 cells.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Antidepressive Agents; Antimetabolit | 2000 |
Nucleoside diphosphate kinase beta (Nm23-R1/NDPKbeta) is associated with intermediate filaments and becomes upregulated upon cAMP-induced differentiation of rat C6 glioma.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Cell Differentiation; Cyclic AMP; Cyto | 2000 |
Protein tyrosine kinase-dependent regulation of adenylate cyclase and phosphatidylinositol 3-kinase activates the expression of glial fibrillary acidic protein upon induction of differentiation in rat c6 glioma.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Androstadienes; Animals; Anti-Bacterial Agents; Benzoqu | 2001 |
Agonist-mediated down-regulation of rat beta1-adrenergic receptor transcripts: role of potential post-transcriptional degradation factors.
Topics: 3' Untranslated Regions; Adrenergic beta-Agonists; Animals; Antigens, Surface; Base Sequence; Blotti | 2001 |
In vivo labelling of beta-adrenergic receptors on rat glioma cells.
Topics: Adrenergic beta-Antagonists; Animals; Cell Line; Glioma; Isoproterenol; Kinetics; Phentolamine; Pind | 1977 |
Regulation of nerve growth factor content in C6 glioma cells by beta-adrenergic receptor stimulation.
Topics: Adrenergic beta-Antagonists; Cyclic AMP; Glioma; Isoproterenol; Nerve Growth Factors; Neuroglia; Neu | 1977 |
Desensitization of beta receptor mediated cyclic AMP response of cultured fibroblasts by partial agonists.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cells, Cultured; Cyclic AMP; Fibrobl | 1979 |
The regulation of adenosine 3':5'-cyclic monophosphate accumulation in glia by alpha-adrenergic agonists.
Topics: Adrenergic alpha-Agonists; Cyclic AMP; Glioma; Humans; In Vitro Techniques; Isoproterenol; Neuroglia | 1979 |
Quantitative relationship between beta-adrenergic receptor number and physiologic responses as studied with a long-lasting beta-adrenergic antagonist.
Topics: Adrenergic beta-Antagonists; Animals; Cell Line; Cyclic AMP; Glioma; Guinea Pigs; Heart Atria; In Vi | 1979 |
Cyclic AMP, membrane transport and cell division. I. Effects of various chemicals on cyclic AMP levels and rate of transport of neucleosides, hypoxanthine and deoxyglucose in several lines of cultured cells.
Topics: Animals; Biological Transport, Active; Bucladesine; Carcinoma, Hepatocellular; Cell Division; Cell L | 1975 |
Measurements of adenosine 3':5'-cyclic monophosphate and membrane potential in neuroblastoma times glioma hybrid cells: opiates and adrenergic agonists cause effects opposite to those of prostaglandin E1.
Topics: Animals; Cell Line; Clone Cells; Cyclic AMP; Dopamine; Glioma; Haloperidol; Hybrid Cells; Isoprotere | 1975 |
Cyclic AMP-mediated induction of ornithine decarboxylase of glioma and neuroblastoma cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Bucladesine; Carboxy-Lyases; Cell Line; Cyclic AMP; | 1975 |
Drug-induced alterations in morphology and level of cAMP in cultured human glioma cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenine; Catecholamines; Cell Line; Cyclic AMP; Cycl | 1975 |
Affinity isolation of cultured tumor cells by means of drugs and hormones covalently bound to glass and Sepharose beads.
Topics: Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Animals; Cell Membrane; Cell Separation; Cells | 1976 |
Desensitization of beta-adrenergic receptors of glioma cells: studies with intact and broken cell preparations.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Cell Line; Cyclic AMP; Dose-Response Relationship, Drug; Glioma | 1976 |
Use of (-)-[3H]dihydroalprenolol to study beta adrenergic receptor-adenylate cyclase coupling in C6 glioma cells: role of 5'-guanylylimidodiphosphate.
Topics: Adenylyl Cyclases; Alprenolol; Binding Sites; Clone Cells; Drug Interactions; Enzyme Activation; Gli | 1977 |
Reduction in beta-adrenergic response of cultured glioma cells following depletion of intracellular GTP.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Cell Line; Cell Membrane; Cyclic AMP; Enzyme Activation; | 1977 |
Impairment of hormone dependent signal transfer by chronic SSPE virus infection.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cyclic AMP; Glioma; Isoproterenol; Rats; Receptors, Adrenergi | 1979 |
Induction of S-adenosyl-L-methionine decarboxylase in glioma and neuroblastoma cells.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Cell Line; Culture Media; Enzyme Inductio | 1977 |
Calcium fluxes in cultured and bulk isolated neuronal and glial cells.
Topics: Acetylcholine; Animals; Astrocytes; Brain Neoplasms; Calcium; Cells, Cultured; Choline; Glioma; Huma | 1977 |
Glucocorticoid-mediated down regulation of c-fos mRNA in C6 glioma cells: lack of correlation with proenkephalin mRNA.
Topics: Animals; Base Sequence; Brain; Cell Line; Dexamethasone; Enkephalins; Gene Expression Regulation, Ne | 1992 |
Dose-dependent down-regulation of beta-adrenoceptors by isoproterenol in rat C6 glioma cells.
Topics: Animals; Cyclic AMP; Dose-Response Relationship, Drug; Down-Regulation; Glioma; Isoproterenol; Rats; | 1992 |
Beta-adrenergic stimulation of C6 glioma cells: effects of cAMP overproduction on cellular metabolites. A multinuclear NMR study.
Topics: Adenosine Triphosphate; Animals; Carbon Isotopes; Cyclic AMP; Glioma; Glucose; Glutamates; Glutamine | 1992 |
Altered genetic response to beta-adrenergic receptor activation in late passage C6 glioma cells.
Topics: Actins; Amyloid beta-Protein Precursor; Animals; Blotting, Northern; Bucladesine; Cell Division; Enk | 1992 |
Pre-steady state study of beta-adrenergic and purinergic receptor interaction in C6 cell membranes: undelayed balance between positive and negative coupling to adenylyl cyclase.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Cell Memb | 1992 |
Idazoxan down-regulates beta-adrenoceptors on C6 glioma cells in vitro.
Topics: Adrenergic alpha-Antagonists; Animals; Autoradiography; Cholera Toxin; Colforsin; Cyclic AMP; Dioxan | 1992 |
2-Aminopurine inhibits RNA and protein synthesis and reduces catecholamine desensitization in C6-2B rat glioma cells.
Topics: 2-Aminopurine; 3T3 Cells; Animals; Bucladesine; Catecholamines; Colforsin; Cyclic AMP; Drug Interact | 1992 |
Cyclic AMP-induced upregulation of proteolipid protein and myelin associated glycoprotein gene expression in C6 cells.
Topics: Animals; Blotting, Northern; Cell Nucleus; Colforsin; Cyclic AMP; Glioma; Isoproterenol; Myelin Prot | 1992 |
Serum-induced sensitization of cyclic AMP accumulation in C62B rat glioma cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Physiological Phenomena; Cyclic AMP; Glioma; Isoproteren | 1992 |
Astroglial membrane structure is affected by agents that raise cyclic AMP and by phosphatidylcholine phospholipase C.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Astrocytes; Cattle; Ce | 1992 |
The beta-adrenoceptor-coupled adenylate cyclase system in rat C6 glioma cells. Deamplification by isoproterenol and oxaprotiline.
Topics: Adenylyl Cyclases; Animals; Antidepressive Agents; Autoradiography; Blotting, Northern; Brain Neopla | 1992 |
Functional analysis of rabbit anti-peptide antibodies which mimic autoantibodies against the beta 1-adrenergic receptor in patients with idiopathic dilated cardiomyopathy.
Topics: Amino Acid Sequence; Animals; Autoantibodies; Binding Sites; Binding, Competitive; Cardiomyopathy, H | 1991 |
Beta-adrenergic treatment of C6 glioma cells produces opposite changes in c-fos and c-jun mRNA levels.
Topics: Adrenergic beta-Agonists; Animals; Blotting, Northern; Dose-Response Relationship, Drug; Glioma; Iso | 1991 |
Inhibition of cAMP accumulation by intracellular calcium mobilization in C6-2B cells stably transfected with substance K receptor cDNA.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenylyl Cyclases; Anim | 1991 |
Evidence for cAMP and cholate extrusion in C6 rat glioma cells by a common anion efflux pump.
Topics: Animals; Antimycin A; Biological Transport, Active; Cholic Acids; Cyclic AMP; Glioma; Isoproterenol; | 1991 |
Differential down-regulation of beta 1- and beta 2-adrenergic receptor mRNA in C6 glioma cells.
Topics: Adrenergic beta-Antagonists; Animals; Betaxolol; Cell Division; Down-Regulation; Glioma; Isoproteren | 1990 |
Reovirus type 3 binds to antagonist domains of the beta-adrenergic receptor.
Topics: Adrenal Gland Neoplasms; Animals; Binding, Competitive; Dihydroalprenolol; Glioma; Isoproterenol; Ki | 1990 |
Regulation of cAMP levels by protein kinase C in C6 rat glioma cells.
Topics: Animals; Colforsin; Cyclic AMP; Glioma; Isoproterenol; Protein Kinase C; Rats; Receptors, Adrenergic | 1990 |
Thrombin reverts the beta-adrenergic agonist-induced morphological response in rat glioma C6 cells.
Topics: Animals; Antithrombin III; Astrocytes; Blood; Calcium; Culture Media; Epithelial Cells; Glioma; Hiru | 1990 |
Identification and characterization of the beta-adrenergic receptor on neuroblastoma x glioma hybrid NG108-15 cells.
Topics: Alprenolol; Bucladesine; Catecholamines; Cell Differentiation; Dihydroalprenolol; Glioma; Hybrid Cel | 1990 |
Activation and de novo synthesis of transglutaminase in cultured glioma cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Line; Cells, Cultured; Cycloheximide; Dactinomycin; Fluor | 1985 |
Rat interferon inhibits catecholamine-inducible synthesis of lactic dehydrogenase in rat glial tumoral C6 cells.
Topics: Animals; Catecholamines; Cells, Cultured; Enzyme Induction; Glioma; Interferons; Isoproterenol; L-La | 1986 |
ADP and, indirectly, ATP are potent inhibitors of cAMP production in intact isoproterenol-stimulated C6 glioma cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylate Cyclase Toxin; Animals; Cyclic AMP; Glioma; | 1989 |
Identification of functional beta-adrenergic receptors on AC glioma cells.
Topics: Animals; Cyclic AMP; Ethanolamines; Glioma; Isoproterenol; Metoprolol; Norepinephrine; Rats; Recepto | 1989 |
Signal transduction by membrane receptors in viable electropermeabilized cells: isoproterenol-stimulated cyclic AMP synthesis in C6 glioma cells.
Topics: Adenosine Triphosphate; Adrenergic beta-Antagonists; Animals; Cell Line; Cell Membrane; Cell Membran | 1989 |
Effect of sodium butyrate on S-100 protein levels and the cAMP response.
Topics: Animals; Butyrates; Butyric Acid; Colforsin; Cyclic AMP; Glial Fibrillary Acidic Protein; Glioma; Hu | 1987 |
Influence of opioids on beta-receptors down-regulation: studies in cultured C6 glioma cells.
Topics: Animals; Cell Line; Cell Membrane; Cyclic AMP; Desipramine; Glioma; Isoproterenol; Kinetics; Morphin | 1987 |
[Treatment of rat glioma with a beta-adrenergic agonist and a phosphodiesterase inhibitor in vivo].
Topics: Animals; Brain Neoplasms; Cyclic AMP; Glioma; Injections, Spinal; Isoproterenol; Meningeal Neoplasms | 1987 |
A quenched-flow study of a receptor-triggered second messenger response: cyclic AMP burst elicited by isoproterenol in C6 glioma cell membranes.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Cyclic AMP; Glioma; Is | 1988 |
Beta-adrenergic receptor regulation of NGF-mRNA content in rat C6-2B glioma cells.
Topics: Animals; Astrocytoma; Glioma; Isoproterenol; Nerve Growth Factors; Rats; Receptors, Adrenergic, beta | 1987 |
Stimulation of nerve growth factor mRNA content in C6 glioma cells by a beta-adrenergic receptor and by cyclic AMP.
Topics: Animals; Blotting, Northern; Cell Line; Colforsin; Cyclic AMP; Glioma; Isoproterenol; Molecular Weig | 1988 |
Irreversible blockade of beta-adrenergic receptors with a bromoacetyl derivative of pindolol.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Dihydroalprenolol; Erythrocytes; Glioma; In | 1985 |
Phorbol esters and beta-adrenergic agonists mediate desensitization of adenylate cyclase in rat glioma C6 cells by distinct mechanisms.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Caenorhabditis elegans Proteins; Carrier Prote | 1985 |
Selective regulation of beta-1 and beta-2 adrenergic receptors by atypical agonists.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Celiprolol; Cells, Cultured; Glioma; Guanosine | 1985 |
Evidence for the appearance of an uncoupled form of the beta-adrenergic receptor distinct from the internalized receptor.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cell Membrane; Cells, Cultured; Dose | 1986 |
Exfoliation of the beta-adrenergic receptor and the regulatory components of adenylate cyclase by cultured rat glioma C6 cells.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; A | 1986 |
Down-regulation of gonadotropin and beta-adrenergic receptors by hormones and cyclic AMP.
Topics: Animals; Bucladesine; Cell Line; Cholera Toxin; Chorionic Gonadotropin; Cyclic AMP; Glioma; Isoprote | 1985 |
The effect of polar head group substitution on phospholipid methylation and the beta-adrenergic response in C6 glial cells.
Topics: Animals; Cell Line; Cell Membrane; Cyclic AMP; Glioma; Isoproterenol; Methylation; Methyltransferase | 1985 |
Turnover of beta 1- and beta 2-adrenergic receptors after down-regulation or irreversible blockade.
Topics: Animals; Cell Line; Cell Membrane; Cycloheximide; Glioma; Iodocyanopindolol; Isoproterenol; Kinetics | 1986 |
Effect of the tricyclic antidepressant desipramine on beta-adrenergic receptors in cultured rat glioma C6 cells.
Topics: Adenylyl Cyclases; Alprenolol; Animals; Cells, Cultured; Cyclic AMP; Desipramine; Glioma; Isoprotere | 1987 |
Transient increase in intracellular concentration of adenosine 3':5'-cyclic monophosphate results in morphological and biochemical differentiation of C6 glioma cells in culture.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Cell Differentiation; Cell Division; Cell L | 1987 |
Guanine nucleotide activation of adenylate cyclase in saponin permeabilized glioma cells.
Topics: Adenylyl Cyclases; Cell Line; Cell Membrane Permeability; Enzyme Activation; Glioma; Guanine Nucleot | 1986 |
Forskolin induction of S-100 protein in glioma and hybrid cells.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Cell Line; Colforsin; Cycloheximide; Dactinomycin; Diterpen | 1985 |
Cyclic AMP-mediated induction of the cyclic AMP phosphodiesterase of C-6 glioma cells.
Topics: Animals; Bucladesine; Cell Line; Cyclic AMP; Cycloheximide; Dactinomycin; Enzyme Induction; Glioma; | 1974 |
Biologically active catecholamines covalentyly bound to glass beads.
Topics: Animals; Catecholamines; Cell Line; Chick Embryo; Clone Cells; Culture Techniques; Cyclic AMP; Dogs; | 1972 |
Expression of genes for metabolism of cyclic adenosine 3':5'-monophosphate in somatic cells. I. Responses to catecholamines in parental and hybrid cells.
Topics: Adenocarcinoma; Animals; Cell Line; Chromosomes; Clone Cells; Cyclic AMP; Electrophoresis, Starch Ge | 1973 |
Probenecide sensitive 3'-5'-cyclic AMP secretion by isoproterenol stimulated glial cells in culture.
Topics: Animals; Cattle; Cells, Cultured; Chromatography, DEAE-Cellulose; Clone Cells; Cyclic AMP; Glioma; I | 1974 |
Effect of catecholamines on the adenosine 3':5'-cyclic monophosphate concentrations of clonal satellite cells of neurons.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aminobutyrates; Animals; Astrocytoma; Car | 1971 |