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isoproterenol and Glaucoma

isoproterenol has been researched along with Glaucoma in 19 studies

Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.

Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)

Research Excerpts

ExcerptRelevanceReference
"D-isoproterenol d-bitartrate applied topically lowers intraocular pressure (IOP) in normal albino rabbits and rabbits with alpha-chymotrypsin-induced glaucoma."7.65The effect of d-isoproterenol on intraocular pressure of the rabbit, monkey, and man. ( Bausher, LP; Kass, MA; Neufeld, AH; Reid, TW; Sears, ML, 1976)
"D-isoproterenol d-bitartrate applied topically lowers intraocular pressure (IOP) in normal albino rabbits and rabbits with alpha-chymotrypsin-induced glaucoma."3.65The effect of d-isoproterenol on intraocular pressure of the rabbit, monkey, and man. ( Bausher, LP; Kass, MA; Neufeld, AH; Reid, TW; Sears, ML, 1976)
"Topical administration of Isoproterenol reduces the intraocular pressure in glaucomatous eyes, but produces systemic side-effects (tachycardia arterial hypotension) that make its clinical use unadvisable."3.65[On the possibility of reducing systemic side-effects of isoproterenol eyedrops by means of topical propranolol (author's transl)]. ( Bucci, MG; Pescosolido, N, 1977)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199017 (89.47)18.7374
1990's2 (10.53)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
LEBENSOHN, JE2
MONNINGER, RH2
MACRI, FJ1
Nathanson, JA1
Polgar, P1
Bodor, N1
Zschauer, AO1
Davis, EB1
Anderson, DR1
Virno, M2
Pellegrino, N2
Pecori-Giraldi, J2
Cozza, R1
Kupfer, C1
Kass, MA1
Reid, TW1
Neufeld, AH1
Bausher, LP1
Sears, ML1
Bucci, MG1
Pescosolido, N1
Bietti, G1
Motolese, E1
Ross, RA2
Drance, SM2
Holland, MG2
Wei, CP1
Langham, ME1
Ershkovich, IG1
Lozovaia, GN1
Fortenberry, B1
Kagawa, CM1
Leaders, FE2
McDonald, TO1
Hodges, JW1
Borgmann, AR1

Reviews

2 reviews available for isoproterenol and Glaucoma

ArticleYear
Autonomic drugs in ophthalmology: some problems and promises. Section III: Sympathomimetic drugs.
    Annals of ophthalmology, 1974, Volume: 6, Issue:9

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Aqueous Humor; Cats; Cornea; Depression, Chemical; Epi

1974
Role of adrenergic mechanisms in development and therapy of open-angled glaucoma.
    Proceedings of the Royal Society of Medicine, 1971, Volume: 64, Issue:6

    Topics: Adolescent; Adult; Animals; Aqueous Humor; Dibenzocycloheptenes; Drug Synergism; Epinephrine; Glauco

1971

Other Studies

17 other studies available for isoproterenol and Glaucoma

ArticleYear
Topical isopropylarterenol (isuprel) as adjuvant therapy in noncongestive glaucoma.
    American journal of ophthalmology, 1957, Volume: 43, Issue:3

    Topics: Combined Modality Therapy; Glaucoma; Glaucoma, Open-Angle; Humans; Isoproterenol; Norepinephrine

1957
Topical isopropylarterenol (isuprel) as adjuvant therapy in noncongestive glaucoma.
    American journal of ophthalmology, 1957, Volume: 43, Issue:3

    Topics: Combined Modality Therapy; Glaucoma; Glaucoma, Open-Angle; Humans; Isoproterenol; Norepinephrine

1957
Topical isopropylarterenol (isuprel) as adjuvant therapy in noncongestive glaucoma.
    American journal of ophthalmology, 1957, Volume: 43, Issue:3

    Topics: Combined Modality Therapy; Glaucoma; Glaucoma, Open-Angle; Humans; Isoproterenol; Norepinephrine

1957
Topical isopropylarterenol (isuprel) as adjuvant therapy in noncongestive glaucoma.
    American journal of ophthalmology, 1957, Volume: 43, Issue:3

    Topics: Combined Modality Therapy; Glaucoma; Glaucoma, Open-Angle; Humans; Isoproterenol; Norepinephrine

1957
THE CONSTRICTOR ACTION FOR VARIOUS ANTI-GLAUCOMA DRUGS ON THE IRIS ARTERY OF THE CAT.
    International journal of neuropharmacology, 1964, Volume: 3

    Topics: Acetazolamide; Arteries; Cats; Epinephrine; Glaucoma; Iris; Isoflurophate; Isoproterenol; Norepineph

1964
Adrenergic regulation of intraocular pressure: identification of beta 2-adrenergic-stimulated adenylate cyclase in ciliary process epithelium.
    Proceedings of the National Academy of Sciences of the United States of America, 1980, Volume: 77, Issue:12

    Topics: Adenylyl Cyclases; Animals; Ciliary Body; Enzyme Activation; Epithelium; Glaucoma; Intraocular Press

1980
Minimal cardiac electrophysiological activity of alprenoxime, a site-activated ocular beta-blocker, in dogs.
    Life sciences, 1995, Volume: 56, Issue:14

    Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Antihypertensive Agents; Biotransformation; Dogs;

1995
Glaucoma, capillaries and pericytes. 4. Beta-adrenergic activation of cultured retinal pericytes.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1996, Volume: 210, Issue:5

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Blood Flow Velocity; Capillaries; Ca

1996
Adrenergic drugs: ocular vasomotricity and vascular permeability.
    Bibliotheca anatomica, 1979, Issue:18

    Topics: Aqueous Humor; Capillary Permeability; Epinephrine; Eye; Glaucoma; Humans; Isoproterenol; Osmotic Pr

1979
Drugs and glaucoma.
    Ophthalmology, 1978, Volume: 85, Issue:3

    Topics: Adult; Age Factors; Aged; Aqueous Humor; Circadian Rhythm; Epinephrine; Glaucoma; Humans; Intraocula

1978
[Sympathomimetic and sympatholytic drugs in the therapy of glaucoma (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1977, Volume: 171, Issue:4

    Topics: Albuterol; Clonidine; Epinephrine; Glaucoma; Humans; Isoproterenol; Norepinephrine; Propranolol; Sym

1977
The effect of d-isoproterenol on intraocular pressure of the rabbit, monkey, and man.
    Investigative ophthalmology, 1976, Volume: 15, Issue:2

    Topics: Administration, Topical; Animals; Chymotrypsin; Glaucoma; Haplorhini; Humans; Intraocular Pressure;

1976
[On the possibility of reducing systemic side-effects of isoproterenol eyedrops by means of topical propranolol (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1977, Volume: 170, Issue:4

    Topics: Adolescent; Adult; Glaucoma; Humans; Intraocular Pressure; Isoproterenol; Ophthalmic Solutions; Prop

1977
Possibility of isoproterenol therapy with soft contact lenses: ocular hypotension without systemic effects.
    Annals of ophthalmology, 1976, Volume: 8, Issue:7

    Topics: Animals; Contact Lenses, Hydrophilic; Depression, Chemical; Glaucoma; Humans; Isoproterenol; Rabbits

1976
The effects of the catecholamines and related drugs on intraocular pressure.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1975, Volume: 10, Issue:2

    Topics: Aqueous Humor; Catecholamines; Ciliary Body; Drug Therapy, Combination; Epinephrine; Glaucoma; Human

1975
Chemical sympathectomy in glaucoma therapy: an investigation of alpha and beta adrenergic supersensitivity.
    Annals of ophthalmology, 1973, Volume: 5, Issue:7

    Topics: Aqueous Humor; Drug Hypersensitivity; Eye; Glaucoma; Humans; Hydroxydopamines; Intraocular Pressure;

1973
[The use of Euspiran in glaucoma].
    Vestnik oftalmologii, 1967, Volume: 80, Issue:6

    Topics: Adult; Aged; Glaucoma; Humans; Intraocular Pressure; Isoproterenol; Male; Middle Aged

1967
A chemically induced experimental ocular hypertension for evaluating drug effects in albino rabbits.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1969, Volume: 131, Issue:2

    Topics: Animals; Carbachol; Epinephrine; Female; Formaldehyde; Glaucoma; Hypertension; Intraocular Pressure;

1969
The water-loading test in rabbits. A method to detect potential ocular hypotensive drugs.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1969, Volume: 82, Issue:3

    Topics: Acetazolamide; Animals; Atropine; Carbachol; Dichlorphenamide; Epinephrine; Glaucoma; Hexamethonium

1969
The effects of single instillations of isoproterenol on intraocular pressure in man.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1969, Volume: 4, Issue:4

    Topics: Aged; Blood Pressure; Female; Glaucoma; Humans; Intraocular Pressure; Isoproterenol; Male; Middle Ag

1969