isoproterenol has been researched along with Genetic Predisposition in 9 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In addition, HRC null mice displayed a significantly exaggerated response to the induction of cardiac hypertrophy by isoproterenol compared to their wild-type littermates." | 7.73 | Increased susceptibility to isoproterenol-induced cardiac hypertrophy and impaired weight gain in mice lacking the histidine-rich calcium-binding protein. ( Black, BL; Cornelissen, I; Greene, SB; Heidt, AB; Jaehnig, EJ, 2006) |
| " We studied the response to acute isoproterenol in SUR2 null mice as a model of acute adrenergic stress and found that the episodic coronary vasospasm observed at baseline in SUR2 null mice was alleviated." | 3.74 | Mice lacking sulfonylurea receptor 2 (SUR2) ATP-sensitive potassium channels are resistant to acute cardiovascular stress. ( Chalupsky, K; Earley, JU; Kakkar, R; Makielski, JC; McNally, EM; Shi, NQ; Smelley, M; Stoller, D, 2007) |
| " In addition, HRC null mice displayed a significantly exaggerated response to the induction of cardiac hypertrophy by isoproterenol compared to their wild-type littermates." | 3.73 | Increased susceptibility to isoproterenol-induced cardiac hypertrophy and impaired weight gain in mice lacking the histidine-rich calcium-binding protein. ( Black, BL; Cornelissen, I; Greene, SB; Heidt, AB; Jaehnig, EJ, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, X | 1 |
| Shen, Y | 1 |
| Xie, J | 1 |
| Bao, H | 1 |
| Cao, Q | 1 |
| Wan, R | 1 |
| Xu, X | 1 |
| Zhou, H | 1 |
| Huang, L | 1 |
| Xu, Z | 1 |
| Zhu, W | 1 |
| Hu, J | 1 |
| Cheng, X | 1 |
| Hong, K | 1 |
| Jelinek, M | 1 |
| Wallach, C | 1 |
| Ehmke, H | 1 |
| Schwoerer, AP | 1 |
| El-Battrawy, I | 1 |
| Zhao, Z | 1 |
| Lan, H | 1 |
| Cyganek, L | 1 |
| Tombers, C | 1 |
| Li, X | 1 |
| Buljubasic, F | 1 |
| Lang, S | 1 |
| Tiburcy, M | 1 |
| Zimmermann, WH | 1 |
| Utikal, J | 1 |
| Wieland, T | 1 |
| Borggrefe, M | 1 |
| Zhou, XB | 1 |
| Akin, I | 1 |
| Park, S | 1 |
| Ranjbarvaziri, S | 1 |
| Lay, FD | 1 |
| Zhao, P | 1 |
| Miller, MJ | 1 |
| Dhaliwal, JS | 1 |
| Huertas-Vazquez, A | 1 |
| Wu, X | 1 |
| Qiao, R | 1 |
| Soffer, JM | 1 |
| Rau, C | 1 |
| Wang, Y | 1 |
| Mikkola, HKA | 1 |
| Lusis, AJ | 1 |
| Ardehali, R | 1 |
| Obeyesekere, MN | 1 |
| Klein, GJ | 1 |
| Nattel, S | 1 |
| Leong-Sit, P | 1 |
| Gula, LJ | 1 |
| Skanes, AC | 1 |
| Yee, R | 1 |
| Krahn, AD | 1 |
| Li, L | 1 |
| Li, J | 1 |
| Drum, BM | 1 |
| Chen, Y | 1 |
| Yin, H | 1 |
| Guo, X | 1 |
| Luckey, SW | 1 |
| Gilbert, ML | 1 |
| McKnight, GS | 1 |
| Scott, JD | 1 |
| Santana, LF | 1 |
| Liu, Q | 1 |
| Jaehnig, EJ | 1 |
| Heidt, AB | 1 |
| Greene, SB | 1 |
| Cornelissen, I | 1 |
| Black, BL | 1 |
| Stoller, D | 1 |
| Kakkar, R | 1 |
| Smelley, M | 1 |
| Chalupsky, K | 1 |
| Earley, JU | 1 |
| Shi, NQ | 1 |
| Makielski, JC | 1 |
| McNally, EM | 1 |
| Shusterman, V | 1 |
| Usiene, I | 1 |
| Harrigal, C | 1 |
| Lee, JS | 1 |
| Kubota, T | 1 |
| Feldman, AM | 1 |
| London, B | 1 |
1 review available for isoproterenol and Genetic Predisposition
| Article | Year |
|---|---|
A clinical approach to early repolarization.
Topics: Action Potentials; Athletes; Death, Sudden, Cardiac; Defibrillators, Implantable; Disease Susceptibi | 2013 |
8 other studies available for isoproterenol and Genetic Predisposition
| Article | Year |
|---|---|
A mutation in the CACNA1C gene leads to early repolarization syndrome with incomplete penetrance: A Chinese family study.
Topics: Action Potentials; Adult; Asian People; Calcium Channels, L-Type; China; Electrocardiography; Family | 2017 |
Genetic background dominates the susceptibility to ventricular arrhythmias in a murine model of β-adrenergic stimulation.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Agonists; Animals; Arrhythmias, Cardiac; Gen | 2018 |
Electrical dysfunctions in human-induced pluripotent stem cell-derived cardiomyocytes from a patient with an arrhythmogenic right ventricular cardiomyopathy.
Topics: Action Potentials; Adrenergic beta-Agonists; Arrhythmogenic Right Ventricular Dysplasia; Calcium Sig | 2018 |
Genetic Regulation of Fibroblast Activation and Proliferation in Cardiac Fibrosis.
Topics: Animals; Cardiomyopathies; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Female; Fibr | 2018 |
Loss of AKAP150 promotes pathological remodelling and heart failure propensity by disrupting calcium cycling and contractile reserve.
Topics: A Kinase Anchor Proteins; Animals; Calcineurin; Calcium Signaling; Calcium-Binding Proteins; Cardiom | 2017 |
Increased susceptibility to isoproterenol-induced cardiac hypertrophy and impaired weight gain in mice lacking the histidine-rich calcium-binding protein.
Topics: Animals; Calcium; Calcium-Binding Proteins; Cardiomegaly; Genetic Predisposition to Disease; Isoprot | 2006 |
Mice lacking sulfonylurea receptor 2 (SUR2) ATP-sensitive potassium channels are resistant to acute cardiovascular stress.
Topics: Acute Disease; Adrenergic beta-Agonists; Animals; ATP-Binding Cassette Transporters; Calcium Channel | 2007 |
Strain-specific patterns of autonomic nervous system activity and heart failure susceptibility in mice.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atropi | 2002 |