isoproterenol has been researched along with Drug Withdrawal Symptoms in 39 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Esmolol withdrawal tilt testing is preferable to isoproterenol for provocative testing of syncope in the young, and it appears to be safer." | 7.69 | Esmolol tilt testing with esmolol withdrawal for the evaluation of syncope in the young. ( Ovadia, M; Thoele, D, 1994) |
| " Seven days later, the animals were challenged with a dose of isoproterenol which would produce massive myocardial infarction and 50-60% mortality in non-treated animals." | 7.67 | Prolonged protective effects following propranolol withdrawal against isoproterenol-induced myocardial infarction in normotensive and hypertensive rats. ( Wexler, BC, 1985) |
| "Esmolol withdrawal tilt testing is preferable to isoproterenol for provocative testing of syncope in the young, and it appears to be safer." | 3.69 | Esmolol tilt testing with esmolol withdrawal for the evaluation of syncope in the young. ( Ovadia, M; Thoele, D, 1994) |
| " Seven days later, the animals were challenged with a dose of isoproterenol which would produce massive myocardial infarction and 50-60% mortality in non-treated animals." | 3.67 | Prolonged protective effects following propranolol withdrawal against isoproterenol-induced myocardial infarction in normotensive and hypertensive rats. ( Wexler, BC, 1985) |
| " 2 The dosage of each drug administered double-blind was gradually increased over a period of 2 weeks and the dose to produce maximum inhibition of exercise-induced tachycardia was continued for one further week." | 2.65 | The effect of intrinsic sympathomimetic activity on beta-receptor responsiveness after beta-adrenoceptor blockade withdrawal. ( Bhattacharjee, P; Cashin, J; Graham, BR; Prichard, BN; Tomlinson, B; Walden, RJ, 1982) |
| " Tapering propranolol dosage is frequently used in the hope of preventing adverse withdrawal events but the success of such a maneuver has not been shown." | 2.65 | Prevention of propranolol withdrawal mechanism by prolonged small dose propranolol schedule. ( Lutterodt, A; Nattel, S; Rangno, RE, 1982) |
| "Morphine treatment increased free malondialdehyde and decreased vitamin E levels." | 1.35 | Morphine or its withdrawal affects plasma malondialdehyde, vitamin E levels and absence or presence of abstinence signs in rats. ( Accinni, R; Cighetti, G; Pinelli, A; Trivulzio, S, 2009) |
| "Nicotine is a neuroteratogen that targets synaptic function during critical developmental stages and recent studies indicate that CNS vulnerability extends into adolescence, the age at which smoking typically commences." | 1.31 | Adolescent nicotine administration alters serotonin receptors and cell signaling mediated through adenylyl cyclase. ( Cousins, MM; Seidler, FJ; Slikker, W; Slotkin, TA; Xu, Z, 2002) |
| " Dose-response curves were obtained one week prior to pretreatment and 24, 48, 72 and 168 hours after the last dose of propranolol." | 1.27 | Propranolol withdrawal-induced supersensitivity to the chronotropic effects of isoproterenol in the conscious rabbit. ( Tenner, TE, 1983) |
| "Pindolol was given to 10 hypertensive patients in doses of 10 mg b." | 1.26 | Cardiac hyper- and hyporesponsiveness after pindolol withdrawal. ( Langlois, S; Rangno, RE; Stewart, J, 1982) |
| "Propranolol alone was more effective than either chlordiazepoxide or a combination of chlordiazepoxide and propranolol in alleviating the symptoms of the alcohol withdrawal syndrome." | 1.26 | Comparative efficacy of propranolol and chlordiazepoxide in alcohol withdrawal. ( Degani, NC; Sellers, EM; Zilm, DH, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (69.23) | 18.7374 |
| 1990's | 8 (20.51) | 18.2507 |
| 2000's | 4 (10.26) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pinelli, A | 1 |
| Cighetti, G | 1 |
| Trivulzio, S | 1 |
| Accinni, R | 1 |
| Torres, LM | 1 |
| Cefaratti, C | 1 |
| Berti-Mattera, L | 1 |
| Romani, A | 1 |
| Xu, Z | 1 |
| Seidler, FJ | 1 |
| Cousins, MM | 1 |
| Slikker, W | 1 |
| Slotkin, TA | 1 |
| Broadley, KJ | 1 |
| Williams, RG | 1 |
| Hawthorn, MH | 1 |
| Grassby, PF | 1 |
| Zawad, JS | 1 |
| Brown, FC | 1 |
| Manning, AS | 1 |
| Yellon, DM | 1 |
| Coltart, DJ | 1 |
| Hearse, DJ | 1 |
| Walden, RJ | 4 |
| Hernandez, J | 1 |
| Yu, Y | 1 |
| Al-Khader, A | 1 |
| Prichard, BN | 4 |
| Bhattacharjee, P | 2 |
| Tomlinson, B | 3 |
| Cashin, J | 1 |
| Graham, BR | 1 |
| Kistler, K | 1 |
| Davis, JN | 1 |
| Kobayashi, A | 1 |
| Ogawa, K | 1 |
| Yamazaki, N | 1 |
| Nathanson, JA | 1 |
| Redmond, DE | 1 |
| Mackenzie, TB | 1 |
| Popkin, MK | 1 |
| Dziubinski, J | 1 |
| Sheppard, JR | 1 |
| Rangno, RE | 5 |
| Nattel, S | 2 |
| Lutterodt, A | 2 |
| Kuriyama, K | 1 |
| Muramatsu, M | 1 |
| Ohkuma, S | 1 |
| Tamura, J | 1 |
| Giudicelli, Y | 1 |
| Lacasa, D | 1 |
| Agli, B | 1 |
| Leneveu, A | 1 |
| Tenner, TE | 1 |
| Langlois, S | 3 |
| Stewart, J | 1 |
| Szécsi, E | 1 |
| Kohlschütter, S | 1 |
| Schiess, W | 1 |
| Lang, E | 1 |
| Verimer, T | 1 |
| Long, JP | 1 |
| Flynn, JR | 1 |
| Arnerić, SP | 1 |
| Walsh, BJ | 1 |
| Ovadia, M | 1 |
| Thoele, D | 1 |
| Ammer, H | 1 |
| Schulz, R | 1 |
| Mäki, T | 1 |
| Toivonen, L | 1 |
| Koskinen, P | 1 |
| Näveri, H | 1 |
| Härkönen, M | 1 |
| Leinonen, H | 1 |
| Stemmer, PM | 1 |
| Ledyard, TH | 1 |
| Watanabe, AM | 1 |
| Boudoulas, H | 2 |
| Lewis, RP | 1 |
| Kates, RE | 1 |
| Dalamangas, G | 1 |
| Van Loon, G | 1 |
| Myers, JH | 1 |
| Horwitz, LD | 1 |
| Sellers, EM | 1 |
| Zilm, DH | 1 |
| Degani, NC | 1 |
| Tumová, I | 1 |
| Racanská, E | 1 |
| Svec, P | 1 |
| Gilligan, DM | 1 |
| Chan, WL | 1 |
| Stewart, R | 1 |
| Oakley, CM | 1 |
| Swift, RM | 1 |
| DePetrillo, P | 1 |
| Graham, B | 1 |
| Liu, JB | 1 |
| Krukemyer, JJ | 1 |
| Binkley, PF | 1 |
| Lima, JJ | 1 |
| Reeves, RA | 1 |
| Boer, WH | 1 |
| DeLeve, L | 1 |
| Leenen, FH | 1 |
| Lee, SS | 1 |
| Braillon, A | 1 |
| Girod, C | 1 |
| Geoffroy, P | 1 |
| Lebrec, D | 1 |
| Wexler, BC | 1 |
| Aherwadkar, SJ | 1 |
| Efendigil, MC | 1 |
| Coulshed, N | 1 |
1 review available for isoproterenol and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Mechanisms of cardiac supersensitivity to sympathomimetic amines.
Topics: Animals; Guinea Pigs; Heart; Humans; Hydroxydopamines; Isoproterenol; Metaproterenol; Oxidopamine; R | 1984 |
7 trials available for isoproterenol and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
The effect of intrinsic sympathomimetic activity on beta-receptor responsiveness after beta-adrenoceptor blockade withdrawal.
Topics: Adrenergic beta-Antagonists; Adult; Catecholamines; Female; Humans; Isoproterenol; Male; Physical Ex | 1982 |
Prevention of propranolol withdrawal mechanism by prolonged small dose propranolol schedule.
Topics: Adult; Aged; Blood Pressure; Dose-Response Relationship, Drug; Drug Administration Schedule; Epineph | 1982 |
Comparison of withdrawal phenomena after propranolol, metoprolol, and pindolol.
Topics: Adult; Aged; Blood Pressure; Heart Rate; Humans; Hypertension; Isoproterenol; Metoprolol; Middle Age | 1982 |
Abrupt withdrawal of pindolol or metoprolol after chronic therapy.
Topics: Adult; Blood Pressure; Drug Hypersensitivity; Electrocardiography; Female; Heart Rate; Humans; Isopr | 1982 |
Withdrawal phenomena after atenolol and bopindolol: haemodynamic responses in healthy volunteers.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Exercise Test; Female; Heart Rate; Hor | 1990 |
Comparison of hypersensitivity to adrenergic stimulation after abrupt withdrawal of propranolol and nadolol: influence of half-life differences.
Topics: Adult; Blood Pressure; Half-Life; Heart Rate; Humans; Isoproterenol; Male; Nadolol; Propranolol; Pul | 1990 |
Beta-blockade disappearance rate predicts beta-adrenergic hypersensitivity.
Topics: Adult; Clinical Trials as Topic; Hemodynamics; Humans; Isoproterenol; Male; Nadolol; Propranolol; Ra | 1989 |
31 other studies available for isoproterenol and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Morphine or its withdrawal affects plasma malondialdehyde, vitamin E levels and absence or presence of abstinence signs in rats.
Topics: Animals; Isoproterenol; Male; Malondialdehyde; Morphine; Naloxone; Narcotic Antagonists; Narcotics; | 2009 |
Delayed restoration of Mg2+ content and transport in liver cells following ethanol withdrawal.
Topics: Adrenergic Agonists; Alcohol Drinking; Alcoholism; Animals; Biological Transport; Bucladesine; Cell | 2009 |
Adolescent nicotine administration alters serotonin receptors and cell signaling mediated through adenylyl cyclase.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Brain Chemistry; Colforsin; Female; GTP | 2002 |
Beta-adrenergic coupled phospholipid methylation. A possible role in withdrawal from chronic ethanol.
Topics: Alcoholism; Animals; Cerebral Cortex; Epinephrine; Ethanol; Humans; Isoproterenol; Kinetics; Male; M | 1984 |
Abrupt withdrawal of chronic beta-blockade: adaptive changes in cyclic AMP and contractility.
Topics: Adaptation, Physiological; Adrenergic beta-Antagonists; Animals; Cyclic AMP; Heart; Heart Rate; Huma | 1981 |
Withdrawal of beta-blocking drugs.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Heart Rate; Humans; Isoproterenol; Male; Middle Aged; | 1982 |
[Withdrawal of preparations blocking beta-adrenergic receptors].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Animals; Catecholamines; Coronary Disease; Dose-Respon | 1982 |
beta-adrenergic supersensitivity in rat brainstem during clonidine withdrawal.
Topics: Animals; Brain Stem; Clonidine; Cyclic AMP; Dihydroalprenolol; Humans; Isoproterenol; Male; Proprano | 1980 |
Changes of cyclic AMP concentration to isoproterenol after abrupt cessation of propranolol in rats.
Topics: Animals; Cyclic AMP; Humans; Isoproterenol; Male; Myocardium; Oxygen; Propranolol; Rats; Receptors, | 1980 |
Morphine withdrawal causes subsensitivity of adrenergic receptor response.
Topics: Adenylyl Cyclases; Animals; Cerebellum; Chlorocebus aethiops; Female; Humans; Isoproterenol; Male; M | 1981 |
Effects of caffeine withdrawal on isoproterenol-stimulated cyclic adenosine monophosphate.
Topics: Adrenal Medulla; Adult; Alprostadil; Caffeine; Cyclic AMP; Drug Tolerance; Humans; In Vitro Techniqu | 1981 |
Alteration in the effect of GTP on cerebral beta-adrenergic receptor binding during morphine withdrawal.
Topics: Animals; Dihydroalprenolol; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Isoproterenol | 1983 |
Comparison of changes in the characteristics of beta-adrenoceptors and responsiveness of human circulating lymphocytes during and after chronic administration of pindolol and propranolol.
Topics: Adult; Cell Membrane; Cyclic AMP; Dihydroalprenolol; Humans; Isoproterenol; Lymphocytes; Male; Pindo | 1984 |
Propranolol withdrawal-induced supersensitivity to the chronotropic effects of isoproterenol in the conscious rabbit.
Topics: Animals; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Isoproterenol; Male; Proprano | 1983 |
Metoprolol withdrawal phenomena: mechanism and prevention.
Topics: Adult; Aged; Blood Pressure; Drug Administration Schedule; Epinephrine; Heart Rate; Humans; Isoprote | 1982 |
Cardiac hyper- and hyporesponsiveness after pindolol withdrawal.
Topics: Adult; Blood Pressure; Catecholamines; Female; Heart; Heart Rate; Humans; Isoproterenol; Male; Metop | 1982 |
Subsensitivity of the presynaptic dopamine receptors in cat heart after the termination of chronic haloperidol treatment.
Topics: Animals; Apomorphine; Blood Pressure; Cats; Female; Haloperidol; Heart; Humans; In Vitro Techniques; | 1981 |
Esmolol tilt testing with esmolol withdrawal for the evaluation of syncope in the young.
Topics: Adolescent; Adrenergic beta-Antagonists; Bradycardia; Contraindications; Female; Humans; Hypotension | 1994 |
Chronic morphine treatment increases stimulatory beta-2 adrenoceptor signaling in A431 cells stably expressing the mu opioid receptor.
Topics: Adenylyl Cyclases; Analgesics, Opioid; Animals; Cells, Cultured; Cyclic AMP; Enkephalin, Ala(2)-MePh | 1997 |
Effect of ethanol drinking, hangover, and exercise on adrenergic activity and heart rate variability in patients with a history of alcohol-induced atrial fibrillation.
Topics: Adrenergic beta-Agonists; Adult; Alcohol Drinking; Atrial Fibrillation; Catecholamines; Cyclic AMP; | 1998 |
Protein dephosphorylation rates in myocytes after isoproterenol withdrawal.
Topics: Acetylcholine; Animals; Calcium-Binding Proteins; Cardiotonic Agents; Carrier Proteins; Female; Guin | 2000 |
Hypersensitivity to adrenergic stimulation after propranolol withdrawal in normal subjects.
Topics: Administration, Oral; Adult; Heart Rate; Humans; Hypersensitivity; Isoproterenol; Myocardial Contrac | 1977 |
Mechanism of propranolol withdrawal phenomena.
Topics: Adult; Aged; Blood Pressure; Catecholamines; Electrocardiography; Female; Heart Rate; Humans; Isopro | 1979 |
Hemodynamic and metabolic response after abrupt uithdrawal of long-term propranolol.
Topics: Animals; Blood Pressure; Dogs; Epinephrine; Fatty Acids, Nonesterified; Female; Heart; Heart Rate; H | 1978 |
Comparative efficacy of propranolol and chlordiazepoxide in alcohol withdrawal.
Topics: Adult; Alcoholism; Catecholamines; Chlordiazepoxide; Dose-Response Relationship, Drug; Drug Evaluati | 1977 |
[Changes in myocardial sensitivity after sudden with withdrawal of calcium channel blockers].
Topics: Aconitine; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Calcium Chloride; Female; Guinea | 1992 |
Adrenergic hypersensitivity after beta-blocker withdrawal in hypertrophic cardiomyopathy.
Topics: Adult; Aged; Angina Pectoris; Atenolol; Cardiomyopathy, Hypertrophic; Coronary Disease; Drug Hyperse | 1991 |
Human leukocyte beta-adrenergic stimulated cyclic AMP in ethanol intoxication and withdrawal.
Topics: Adrenergic beta-Agonists; Alcoholic Intoxication; Alcoholism; Alprostadil; Cyclic AMP; Humans; In Vi | 1990 |
Haemodynamic rebound phenomena after abrupt cessation of propranolol therapy in portal hypertensive rats.
Topics: Animals; Depression, Chemical; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Hypertens | 1986 |
Prolonged protective effects following propranolol withdrawal against isoproterenol-induced myocardial infarction in normotensive and hypertensive rats.
Topics: Animals; Blood Pressure; Corticosterone; Creatine Kinase; Female; Humans; Isoproterenol; L-Lactate D | 1985 |
Chlorpromazine therapy, and associated acute disturbances of cardiac rhythm.
Topics: Adult; Blood Glucose; Chlorpromazine; Electrocardiography; Female; Haloperidol; Heart Block; Humans; | 1974 |