isoproterenol has been researched along with Diathesis in 24 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study aimed to investigate the potential effects of growth differentiation factor 11 (GDF11) on isoproterenol (ISO)‑induced heart failure (HF) and identify the underlying molecular mechanisms." | 7.91 | Growth differentiation factor 11 is involved in isoproterenol‑induced heart failure. ( Hao, Z; Jia, Y; Li, N; Shi, ZF; Tan, H; Zhang, XJ, 2019) |
| "The electrocardiogram was recorded and serum and bulk myocardial electrolytes were determined in male Sprague Dawley rats, subjected to dietary magnesium deficiency for various periods, to assess the time course of development and cessation of the enhanced arrhythmogenic action of isoproterenol (150 micrograms/kg, subcutaneously) and to establish possible relationships between electrolyte changes and severe ventricular dysrhythmias." | 7.67 | Enhanced incidence of isoproterenol-induced ventricular fibrillation in the magnesium-deficient rat. ( Guideri, G; Horowitz, S; Lehr, D, 1985) |
| "The present study aimed to investigate the potential effects of growth differentiation factor 11 (GDF11) on isoproterenol (ISO)‑induced heart failure (HF) and identify the underlying molecular mechanisms." | 3.91 | Growth differentiation factor 11 is involved in isoproterenol‑induced heart failure. ( Hao, Z; Jia, Y; Li, N; Shi, ZF; Tan, H; Zhang, XJ, 2019) |
| "We conducted genome-wide measurements of DNA methylation in different strains of mice that are susceptible and resistant to isoproterenol-induced dysfunction to test the hypothesis that this epigenetic mark may play a causal role in the development of heart failure." | 3.83 | DNA Methylation Indicates Susceptibility to Isoproterenol-Induced Cardiac Pathology and Is Associated With Chromatin States. ( Chen, H; Lusis, AJ; Orozco, LD; Pellegrini, M; Rau, CD; Ren, S; Rubbi, L; Vondriska, TM; Wang, J; Wang, Y, 2016) |
| " Cardiomyopathy results from cardiac injury, is the leading cause of heart failure, and can be induced in heart failure-prone rats through sub-chronic infusion of isoproterenol (ISO)." | 3.81 | Cardiomyopathy confers susceptibility to particulate matter-induced oxidative stress, vagal dominance, arrhythmia and pulmonary inflammation in heart failure-prone rats. ( Carll, AP; Cascio, WE; Costa, DL; Farraj, AK; Haykal-Coates, N; Hazari, MS; Ledbetter, AD; Richards, JH; Winsett, DW, 2015) |
| "Cardiac hypertrophy was induced in wild-type and IL-10 knockout mice by isoproterenol (ISO) infusion." | 3.78 | Interleukin-10 treatment attenuates pressure overload-induced hypertrophic remodeling and improves heart function via signal transducers and activators of transcription 3-dependent inhibition of nuclear factor-κB. ( Barefield, D; Ghosh, AK; Gupta, R; Hoxha, E; Kishore, R; Krishnamurthy, P; Lambers, E; Mackie, A; Qin, G; Ramirez, V; Sadayappan, S; Singh, N; Thal, M; Verma, SK, 2012) |
| " The effects of isoproterenol (ISP) and chemical sympathectomy (6-hydroxydopamine treatment) on myocardial beta-receptors were also investigated in 10 and 24 week-old SHRS and WKY to examine the effects of hypertension and aging on receptor regulation." | 3.68 | Effects of aging and drugs on myocardial beta-adrenergic receptors in M-SHRSP and SHRSP. ( Ikawa, H; Suzuki, A, 1991) |
| "Blood pressure (BP), plasma levels of norepinephrine (NE) and epinephrine, the chronotropic effect of isoproterenol, and the relationship between variations in BP and concomitant plasma NE levels obtained during NE infusion were studied under control conditions and after 10 days of dietary potassium supplementation (100 mmol/day) in 12 normotensive subjects with negative family history (FH) of hypertension (mean BP 111/70 +/- 9/7 mmHg), 11 normotensive subjects with positive FH (112/73 +/- 8/6 mmHg), and 10 subjects with untreated borderline to mild essential hypertension (131/89 +/- 15/9 mmHg)." | 3.67 | Correction of cardiovascular hypersensitivity to norepinephrine by potassium supplementation in normotensive members of hypertensive families and patients with essential hypertension. ( Beretta-Piccoli, C; Bianchetti, MG; Ferrier, C; Gerber, A; Link, L; Weidmann, P, 1984) |
| "The electrocardiogram was recorded and serum and bulk myocardial electrolytes were determined in male Sprague Dawley rats, subjected to dietary magnesium deficiency for various periods, to assess the time course of development and cessation of the enhanced arrhythmogenic action of isoproterenol (150 micrograms/kg, subcutaneously) and to establish possible relationships between electrolyte changes and severe ventricular dysrhythmias." | 3.67 | Enhanced incidence of isoproterenol-induced ventricular fibrillation in the magnesium-deficient rat. ( Guideri, G; Horowitz, S; Lehr, D, 1985) |
| "Dyslipidemia is an important factor in MetS and is related to atrial fibrillation (AF)." | 1.43 | VLDL from Metabolic Syndrome Individuals Enhanced Lipid Accumulation in Atria with Association of Susceptibility to Atrial Fibrillation. ( Chen, CH; Chu, CS; Hsiao, YL; Ke, LY; Lai, WT; Lee, HC; Lin, HT; Sheu, SH; Shin, SJ; Wei, C; Wu, BN, 2016) |
| "Isoproterenol (ISO) was used to induce AMI." | 1.38 | Increased expression of calcium-sensing receptors in atherosclerosis confers hypersensitivity to acute myocardial infarction in rats. ( Guo, J; Li, GW; Li, HZ; Wang, LC; Wang, R; Xing, WJ; Xu, CQ; Zhang, WH, 2012) |
| "During malignant hyperthermia crisis, cardiac arrhythmias and increased myocardial oxygen consumption are observed." | 1.27 | Effects of beta- and alpha-adrenergic agonists, adenosine, and carbachol in heart muscle isolated from malignant hyperthermia susceptible swine. ( Böhm, M; Roewer, N; Schmitz, W; Scholz, H; Schulte am Esch, J, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (20.83) | 18.7374 |
| 1990's | 5 (20.83) | 18.2507 |
| 2000's | 4 (16.67) | 29.6817 |
| 2010's | 7 (29.17) | 24.3611 |
| 2020's | 3 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Ouyang, F | 1 |
| Liu, X | 1 |
| Liu, G | 1 |
| Qiu, H | 1 |
| He, Y | 1 |
| Hu, H | 1 |
| Jiang, P | 1 |
| Karam, S | 1 |
| Margaria, JP | 1 |
| Bourcier, A | 1 |
| Mika, D | 1 |
| Varin, A | 1 |
| Bedioune, I | 1 |
| Lindner, M | 1 |
| Bouadjel, K | 1 |
| Dessillons, M | 1 |
| Gaudin, F | 1 |
| Lefebvre, F | 1 |
| Mateo, P | 1 |
| Lechène, P | 1 |
| Gomez, S | 1 |
| Domergue, V | 1 |
| Robert, P | 1 |
| Coquard, C | 1 |
| Algalarrondo, V | 1 |
| Samuel, JL | 1 |
| Michel, JB | 1 |
| Charpentier, F | 1 |
| Ghigo, A | 1 |
| Hirsch, E | 1 |
| Fischmeister, R | 1 |
| Leroy, J | 1 |
| Vandecasteele, G | 1 |
| Mashali, MA | 1 |
| Saad, NS | 1 |
| Canan, BD | 1 |
| Elnakish, MT | 1 |
| Milani-Nejad, N | 1 |
| Chung, JH | 1 |
| Schultz, EJ | 1 |
| Kiduko, SA | 1 |
| Huang, AW | 1 |
| Hare, AN | 1 |
| Peczkowski, KK | 1 |
| Fazlollahi, F | 1 |
| Martin, BL | 1 |
| Murray, JD | 1 |
| Campbell, CM | 1 |
| Kilic, A | 1 |
| Whitson, BA | 1 |
| Mokadam, NA | 1 |
| Mohler, PJ | 1 |
| Janssen, PML | 1 |
| Zhang, XJ | 1 |
| Tan, H | 1 |
| Shi, ZF | 1 |
| Li, N | 1 |
| Jia, Y | 1 |
| Hao, Z | 1 |
| Obeyesekere, MN | 1 |
| Klein, GJ | 1 |
| Nattel, S | 1 |
| Leong-Sit, P | 1 |
| Gula, LJ | 1 |
| Skanes, AC | 1 |
| Yee, R | 1 |
| Krahn, AD | 1 |
| Carll, AP | 1 |
| Haykal-Coates, N | 1 |
| Winsett, DW | 1 |
| Hazari, MS | 1 |
| Ledbetter, AD | 1 |
| Richards, JH | 1 |
| Cascio, WE | 1 |
| Costa, DL | 1 |
| Farraj, AK | 1 |
| Lee, HC | 1 |
| Lin, HT | 1 |
| Ke, LY | 1 |
| Wei, C | 1 |
| Hsiao, YL | 1 |
| Chu, CS | 1 |
| Lai, WT | 1 |
| Shin, SJ | 1 |
| Chen, CH | 1 |
| Sheu, SH | 1 |
| Wu, BN | 1 |
| Chen, H | 1 |
| Orozco, LD | 1 |
| Wang, J | 1 |
| Rau, CD | 1 |
| Rubbi, L | 1 |
| Ren, S | 1 |
| Wang, Y | 1 |
| Pellegrini, M | 1 |
| Lusis, AJ | 1 |
| Vondriska, TM | 1 |
| Guo, J | 1 |
| Li, HZ | 1 |
| Wang, LC | 1 |
| Zhang, WH | 1 |
| Li, GW | 1 |
| Xing, WJ | 1 |
| Wang, R | 1 |
| Xu, CQ | 1 |
| Verma, SK | 1 |
| Krishnamurthy, P | 1 |
| Barefield, D | 1 |
| Singh, N | 1 |
| Gupta, R | 1 |
| Lambers, E | 1 |
| Thal, M | 1 |
| Mackie, A | 1 |
| Hoxha, E | 1 |
| Ramirez, V | 1 |
| Qin, G | 1 |
| Sadayappan, S | 1 |
| Ghosh, AK | 1 |
| Kishore, R | 1 |
| Cross, HR | 1 |
| Murphy, E | 1 |
| Steenbergen, C | 1 |
| Nakagawa, M | 1 |
| Ooie, T | 1 |
| Ou, B | 1 |
| Ichinose, M | 1 |
| Takahashi, N | 1 |
| Hara, M | 1 |
| Yonemochi, H | 1 |
| Saikawa, T | 1 |
| Temple, J | 1 |
| Frias, P | 1 |
| Rottman, J | 1 |
| Yang, T | 1 |
| Wu, Y | 1 |
| Verheijck, EE | 1 |
| Zhang, W | 1 |
| Siprachanh, C | 1 |
| Kanki, H | 1 |
| Atkinson, JB | 1 |
| King, P | 1 |
| Anderson, ME | 1 |
| Kupershmidt, S | 1 |
| Roden, DM | 1 |
| Bianchetti, MG | 1 |
| Beretta-Piccoli, C | 1 |
| Weidmann, P | 1 |
| Ferrier, C | 1 |
| Link, L | 1 |
| Gerber, A | 1 |
| Starec, M | 1 |
| Donát, P | 1 |
| Krsiak, M | 1 |
| Rasková, H | 1 |
| Mrăz, M | 1 |
| Van Wagoner, DR | 1 |
| Pond, AL | 1 |
| Lamorgese, M | 1 |
| Rossie, SS | 1 |
| McCarthy, PM | 1 |
| Nerbonne, JM | 1 |
| Niño, J | 1 |
| Villar, JC | 1 |
| Tahvanainen, KU | 1 |
| Kähönen, M | 1 |
| Kuusela, TA | 1 |
| Morillo, CA | 1 |
| Ikawa, H | 1 |
| Suzuki, A | 1 |
| Scholz, J | 1 |
| Roewer, N | 2 |
| Rum, U | 1 |
| Schmitz, W | 2 |
| Scholz, H | 2 |
| Schulte am Esch, J | 2 |
| Riven-Kreitman, R | 1 |
| Tauber-Finkelstein, M | 1 |
| Zipori, D | 1 |
| Shaltiel, S | 1 |
| Collins, MN | 1 |
| Billman, GE | 1 |
| Böhm, M | 1 |
| Guideri, G | 1 |
| Lehr, D | 1 |
| Horowitz, S | 1 |
| Highman, B | 1 |
| Streett, RP | 1 |
| Byers, NT | 1 |
1 review available for isoproterenol and Diathesis
| Article | Year |
|---|---|
A clinical approach to early repolarization.
Topics: Action Potentials; Athletes; Death, Sudden, Cardiac; Defibrillators, Implantable; Disease Susceptibi | 2013 |
1 trial available for isoproterenol and Diathesis
| Article | Year |
|---|---|
Vasovagal susceptibility to nitrate or isoproterenol head-up tilt.
Topics: Adolescent; Adult; Aged; Autonomic Nervous System; Cross-Over Studies; Disease Susceptibility; Femal | 2001 |
22 other studies available for isoproterenol and Diathesis
| Article | Year |
|---|---|
Long non-coding RNA RNF7 promotes the cardiac fibrosis in rat model via miR-543/THBS1 axis and TGFβ1 activation.
Topics: Animals; Biomarkers; Biopsy; Cardiomyopathies; Disease Models, Animal; Disease Susceptibility; Extra | 2020 |
Cardiac Overexpression of PDE4B Blunts β-Adrenergic Response and Maladaptive Remodeling in Heart Failure.
Topics: Adrenergic beta-Agonists; Animals; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Disease | 2020 |
Impact of etiology on force and kinetics of left ventricular end-stage failing human myocardium.
Topics: Biomarkers; Data Analysis; Disease Susceptibility; Female; Heart Failure; Heart Failure, Diastolic; | 2021 |
Growth differentiation factor 11 is involved in isoproterenol‑induced heart failure.
Topics: Animals; Apoptosis; Biomarkers; Cells, Cultured; Disease Models, Animal; Disease Susceptibility; Gen | 2019 |
Cardiomyopathy confers susceptibility to particulate matter-induced oxidative stress, vagal dominance, arrhythmia and pulmonary inflammation in heart failure-prone rats.
Topics: Administration, Inhalation; Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Cardiomyopathie | 2015 |
VLDL from Metabolic Syndrome Individuals Enhanced Lipid Accumulation in Atria with Association of Susceptibility to Atrial Fibrillation.
Topics: Adult; Animals; Apoptosis; Atrial Fibrillation; Cardiac Output; Cardiotonic Agents; Diastole; Diseas | 2016 |
DNA Methylation Indicates Susceptibility to Isoproterenol-Induced Cardiac Pathology and Is Associated With Chromatin States.
Topics: Animals; Cardiotonic Agents; Chromatin; CpG Islands; Disease Susceptibility; DNA Methylation; Female | 2016 |
Increased expression of calcium-sensing receptors in atherosclerosis confers hypersensitivity to acute myocardial infarction in rats.
Topics: Animals; Aorta, Abdominal; Apoptosis; Apoptosis Regulatory Proteins; Atherosclerosis; Cholesterol; C | 2012 |
Interleukin-10 treatment attenuates pressure overload-induced hypertrophic remodeling and improves heart function via signal transducers and activators of transcription 3-dependent inhibition of nuclear factor-κB.
Topics: Animals; Cardiomegaly; Disease Models, Animal; Disease Susceptibility; Fibrosis; Interleukin-10; Iso | 2012 |
Ca(2+) loading and adrenergic stimulation reveal male/female differences in susceptibility to ischemia-reperfusion injury.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Disease Susceptibility; Dose-Response Relationship, Drug | 2002 |
Gender differences in autonomic modulation of ventricular repolarization in humans.
Topics: Adult; Atropine; Autonomic Nervous System; Disease Susceptibility; Electrophysiologic Techniques, Ca | 2005 |
Atrial fibrillation in KCNE1-null mice.
Topics: Action Potentials; Animals; Atrial Fibrillation; Disease Susceptibility; Isoproterenol; Mice; Mice, | 2005 |
Correction of cardiovascular hypersensitivity to norepinephrine by potassium supplementation in normotensive members of hypertensive families and patients with essential hypertension.
Topics: Adult; Blood Pressure; Cardiovascular System; Disease Susceptibility; Dose-Response Relationship, Dr | 1984 |
Behavioral characteristics of two rat strains differing in sensitivity to the cardiotoxic effect of isoprenaline.
Topics: Aggression; Agonistic Behavior; Animals; Behavior, Animal; Cardiotonic Agents; Disease Susceptibilit | 1996 |
Atrial L-type Ca2+ currents and human atrial fibrillation.
Topics: Action Potentials; Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Atrial Fibrillation; Ca | 1999 |
Effects of aging and drugs on myocardial beta-adrenergic receptors in M-SHRSP and SHRSP.
Topics: 5'-Nucleotidase; Aging; Animals; Cardiomegaly; Cerebrovascular Disorders; Disease Susceptibility; Do | 1991 |
Effects of caffeine, halothane, succinylcholine, phenylephrine and isoproterenol on myocardial force of contraction of malignant hyperthermia susceptible swine.
Topics: Animals; Caffeine; Disease Susceptibility; Halothane; Isoproterenol; Malignant Hyperthermia; Myocard | 1991 |
A periodicity in the response of SJL/J thymocytes to isoproterenol. Simulation by cell lines.
Topics: Animals; B-Lymphocytes; Cell Line; Cell Movement; Cells, Cultured; Cyclic AMP; Disease Susceptibilit | 1990 |
Autonomic response to coronary occlusion in animals susceptible to ventricular fibrillation.
Topics: Animals; Autonomic Nervous System; Blood Pressure; Coronary Disease; Coronary Vessels; Death, Sudden | 1989 |
Effects of beta- and alpha-adrenergic agonists, adenosine, and carbachol in heart muscle isolated from malignant hyperthermia susceptible swine.
Topics: Adenosine; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Carbachol; Disease Suscepti | 1988 |
Enhanced incidence of isoproterenol-induced ventricular fibrillation in the magnesium-deficient rat.
Topics: Animals; Calcium; Diet; Disease Susceptibility; Electrocardiography; Electrolytes; Isoproterenol; Ma | 1985 |
Effect of isoproterenol on susceptibility of x-irradiated rats to experimental bacterial endocarditis.
Topics: Animals; Carbon Tetrachloride Poisoning; Disease Susceptibility; Endocarditis, Bacterial; Heart; Iso | 1972 |