isoproterenol has been researched along with Diabetic Cardiomyopathies in 4 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Diabetic Cardiomyopathies: Diabetes complications in which VENTRICULAR REMODELING in the absence of CORONARY ATHEROSCLEROSIS and hypertension results in cardiac dysfunctions, typically LEFT VENTRICULAR DYSFUNCTION. The changes also result in myocardial hypertrophy, myocardial necrosis and fibrosis, and collagen deposition due to impaired glucose tolerance.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This work investigated the protective effect of pioglitazone on myocardial infarction (MI) in non-diabetic and diabetic rats, focusing on its role on advanced glycated endproducts (AGEs) and cardiac apoptotic machinery." | 7.83 | Cardioprotective effect of pioglitazone in diabetic and non-diabetic rats subjected to acute myocardial infarction involves suppression of AGE-RAGE axis and inhibition of apoptosis. ( Farag, NE; Khodeer, DM; Moustafa, YM; Zaitone, SA, 2016) |
| " In a mouse model of isoproterenol-induced cardiac injury, TPGS is not able to affect cardiac remodeling, however combination of vitamin E TPGS and Apelin counteracts myocardial apoptosis, oxidative stress, hypertrophy and fibrosis." | 3.96 | In vitro and in vivo cardioprotective and metabolic efficacy of vitamin E TPGS/Apelin. ( Blanzat, M; Boal, F; Cassel, S; Cinato, M; Dejugnat, C; Jimenez, T; Kunduzova, O; Leme Goto, P; Loi, H; Marsal, D; Merachli, F; Santin, Y; Todua, N; Tronchere, H; Vons, B, 2020) |
| " This work investigated the protective effect of pioglitazone on myocardial infarction (MI) in non-diabetic and diabetic rats, focusing on its role on advanced glycated endproducts (AGEs) and cardiac apoptotic machinery." | 3.83 | Cardioprotective effect of pioglitazone in diabetic and non-diabetic rats subjected to acute myocardial infarction involves suppression of AGE-RAGE axis and inhibition of apoptosis. ( Farag, NE; Khodeer, DM; Moustafa, YM; Zaitone, SA, 2016) |
| " We hypothesized that experimental diabetes in rats combined with a cardiac or renal stressor, would mimic diabetic cardiomyopathy and nephropathy, respectively." | 1.56 | Rat pancreatectomy combined with isoprenaline or uninephrectomy as models of diabetic cardiomyopathy or nephropathy. ( Fink, LN; Jelsing, J; Johansen, TT; Lindsay, RT; Murray, AJ; Pedersen, AA; Pedersen, PJ; Pedersen, TX; Secher, T; Skarsfeldt, T; Thisted, L; Thomsen, MB; Thrane, ST; Zois, NE; Østergaard, MV, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Leme Goto, P | 1 |
| Cinato, M | 1 |
| Merachli, F | 1 |
| Vons, B | 1 |
| Jimenez, T | 1 |
| Marsal, D | 1 |
| Todua, N | 1 |
| Loi, H | 1 |
| Santin, Y | 1 |
| Cassel, S | 1 |
| Blanzat, M | 1 |
| Tronchere, H | 1 |
| Dejugnat, C | 1 |
| Kunduzova, O | 1 |
| Boal, F | 1 |
| Thisted, L | 1 |
| Østergaard, MV | 1 |
| Pedersen, AA | 1 |
| Pedersen, PJ | 1 |
| Lindsay, RT | 1 |
| Murray, AJ | 1 |
| Fink, LN | 1 |
| Pedersen, TX | 1 |
| Secher, T | 1 |
| Johansen, TT | 1 |
| Thrane, ST | 1 |
| Skarsfeldt, T | 1 |
| Jelsing, J | 1 |
| Thomsen, MB | 1 |
| Zois, NE | 1 |
| Yang, Y | 1 |
| Zhao, M | 1 |
| Yu, XJ | 1 |
| Liu, LZ | 1 |
| He, X | 1 |
| Deng, J | 1 |
| Zang, WJ | 1 |
| Khodeer, DM | 1 |
| Zaitone, SA | 1 |
| Farag, NE | 1 |
| Moustafa, YM | 1 |
4 other studies available for isoproterenol and Diabetic Cardiomyopathies
| Article | Year |
|---|---|
In vitro and in vivo cardioprotective and metabolic efficacy of vitamin E TPGS/Apelin.
Topics: Animals; Apelin; Apoptosis; Cardiomegaly; Cardiotonic Agents; Cell Hypoxia; Cell Line; Diabetic Card | 2020 |
Rat pancreatectomy combined with isoprenaline or uninephrectomy as models of diabetic cardiomyopathy or nephropathy.
Topics: Albuminuria; Animals; C-Peptide; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Diabeti | 2020 |
Pyridostigmine regulates glucose metabolism and mitochondrial homeostasis to reduce myocardial vulnerability to injury in diabetic mice.
Topics: Animals; Carbohydrate Metabolism; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Glucos | 2019 |
Cardioprotective effect of pioglitazone in diabetic and non-diabetic rats subjected to acute myocardial infarction involves suppression of AGE-RAGE axis and inhibition of apoptosis.
Topics: Adrenergic beta-Agonists; Animals; Apoptosis; Cardiotonic Agents; Diabetes Mellitus, Type 2; Diabeti | 2016 |