isoproterenol has been researched along with Diabetes Mellitus in 46 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the effect of tolbutamide on insulin release to nonglucose stimuli in non-insulin-dependent diabetes mellitus and how plasma glucose levels may modulate this effect, the acute insulin response (AIR) to an isoproterenol (12 Micrograms) or an arginine (5 g) i." | 7.66 | Insulin responses to nonglucose stimuli in non-insulin-dependent diabetes mellitus during a tolbutamide infusion. ( Beard, JC; Halter, JB; Judzewitsch, R; Pfeifer, MA; Porte, D, 1982) |
| "Urea clearances were not significantly different from usual values." | 5.26 | Peritoneal clearances in scleroderma and diabetes mellitus: effects of intraperitioneal isoproterenol. ( Hirszel, P; Husted, FC; Miller, L; Nolph, KD, 1976) |
| "In chronic pancreatitis with moderate derangements of carbohydrate tolerance (detected by the double glucose test), the basal concentrations of insulin and C-peptide in blood are normal whereas in patients with secondary diabetes mellitus are lowered." | 3.67 | [The effect of pharmacological agents on pancreatic incretory activity in patients with chronic pancreatitis]. ( Geller, LI; Obukhova, GG; Pashko, MM, 1989) |
| "To determine the effect of tolbutamide on insulin release to nonglucose stimuli in non-insulin-dependent diabetes mellitus and how plasma glucose levels may modulate this effect, the acute insulin response (AIR) to an isoproterenol (12 Micrograms) or an arginine (5 g) i." | 3.66 | Insulin responses to nonglucose stimuli in non-insulin-dependent diabetes mellitus during a tolbutamide infusion. ( Beard, JC; Halter, JB; Judzewitsch, R; Pfeifer, MA; Porte, D, 1982) |
| "Obesity is an important risk factor for diabetes mellitus (DM) which is a major global health problem." | 1.72 | Effects of Isoprenaline on ventricular myocyte shortening and Ca ( Howarth, FC; Qureshi, MA; Sultan, A, 2022) |
| " Dose-response dP/dtmax curves were obtained by stepped increases of agonist infusion (iv)." | 1.27 | Enhanced adrenergic sensitivity of the diabetic neonatal heart. ( Downing, SE; Lee, JC, 1985) |
| "Urea clearances were not significantly different from usual values." | 1.26 | Peritoneal clearances in scleroderma and diabetes mellitus: effects of intraperitioneal isoproterenol. ( Hirszel, P; Husted, FC; Miller, L; Nolph, KD, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (76.09) | 18.7374 |
| 1990's | 5 (10.87) | 18.2507 |
| 2000's | 3 (6.52) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (6.52) | 2.80 |
| Authors | Studies |
|---|---|
| Souza Bomfim, GH | 1 |
| Musial, DC | 1 |
| Rocha, K | 1 |
| Jurkiewicz, A | 1 |
| Jurkiewicz, NH | 1 |
| Gattoni, C | 1 |
| Conti, E | 1 |
| Casolo, A | 1 |
| Nuccio, S | 1 |
| Baglieri, C | 1 |
| Capelli, C | 1 |
| Girardi, M | 1 |
| Sultan, A | 1 |
| Qureshi, MA | 1 |
| Howarth, FC | 1 |
| Hegyi, B | 1 |
| Ko, CY | 1 |
| Bossuyt, J | 1 |
| Bers, DM | 1 |
| Liu, YM | 1 |
| Cao, JT | 1 |
| Zheng, YL | 1 |
| Chen, YH | 1 |
| FLIEGEL, W | 1 |
| GADBOYS, HL | 1 |
| WISOFF, G | 1 |
| LITWAK, RS | 1 |
| Wenzel, S | 1 |
| Soltanpour, G | 1 |
| Schlüter, KD | 1 |
| Altura, BM | 1 |
| Altura, BT | 1 |
| Exton, JH | 1 |
| Beretta-Piccoli, C | 1 |
| Weidmann, P | 1 |
| Keusch, G | 1 |
| Pfeifer, MA | 1 |
| Halter, JB | 2 |
| Beard, JC | 1 |
| Judzewitsch, R | 1 |
| Porte, D | 3 |
| McRae, JR | 2 |
| Chen, M | 1 |
| Robertson, RP | 3 |
| Taylor, RL | 1 |
| Conaway, HH | 1 |
| Roth, SI | 1 |
| Sando, H | 1 |
| Lee, YS | 1 |
| Iwamoto, Y | 1 |
| Ikeuchi, M | 1 |
| Kosaka, K | 1 |
| Arner, P | 4 |
| Engfeldt, P | 2 |
| Ostman, J | 3 |
| Metz, SA | 1 |
| Dinçer, UD | 1 |
| Onay, A | 1 |
| Ari, N | 1 |
| Ozçelikay, AT | 1 |
| Altan, VM | 1 |
| Klannemark, M | 1 |
| Orho, M | 1 |
| Langin, D | 1 |
| Laurell, H | 1 |
| Holm, C | 1 |
| Reynisdottir, S | 1 |
| Groop, L | 1 |
| Blaak, EE | 1 |
| Saris, WH | 1 |
| Wolffenbuttel, BH | 1 |
| Huisamen, B | 1 |
| van Zyl, M | 1 |
| Keyser, A | 1 |
| Lochner, A | 1 |
| Levilliers, J | 1 |
| Pairault, J | 1 |
| Lecot, F | 1 |
| Tournemolle, A | 1 |
| Laudat, MH | 1 |
| Adebonojo, FO | 1 |
| Hamilton, CL | 1 |
| Katada, T | 1 |
| Ui, M | 1 |
| Galton, DJ | 2 |
| Reckless, JP | 2 |
| Clifton-Bligh, P | 1 |
| Gilbert, CH | 1 |
| Garber, AJ | 1 |
| Karl, IE | 1 |
| Kipnis, DM | 1 |
| Tutwiler, GF | 1 |
| Kirsch, TJ | 1 |
| Hepp, KD | 1 |
| Dehaye, JP | 1 |
| Winand, J | 1 |
| Poloczek, P | 1 |
| Christophe, J | 1 |
| Graf, RJ | 1 |
| Nolph, KD | 1 |
| Miller, L | 1 |
| Husted, FC | 1 |
| Hirszel, P | 1 |
| Gill, J | 1 |
| Fonseca, V | 1 |
| Dandona, P | 1 |
| Jeremy, JY | 1 |
| Palmer, TM | 1 |
| Taberner, PV | 1 |
| Houslay, MD | 1 |
| Geller, LI | 1 |
| Pashko, MM | 1 |
| Obukhova, GG | 1 |
| Enzi, G | 1 |
| Sergi, G | 1 |
| Pavan, M | 1 |
| Dodi, G | 1 |
| Allegri, F | 1 |
| Digito, M | 1 |
| Baldo-Enzi, G | 1 |
| Downing, SE | 1 |
| Lee, JC | 1 |
| Steinmetz, J | 1 |
| Lowry, L | 1 |
| Yen, TT | 1 |
| Burr, IM | 1 |
| Balant, L | 1 |
| Stauffacher, W | 1 |
| Renold, AE | 1 |
| Atkins, T | 1 |
| Matty, AJ | 1 |
| Cameron, DP | 1 |
| Opat, F | 1 |
| Insch, S | 1 |
| Deckert, T | 2 |
| Lauridsen, UB | 2 |
| Madsen, SN | 2 |
| Mogensen, P | 1 |
| Deckert, M | 1 |
| Brånemark, PI | 1 |
| Fagerberg, SE | 1 |
| Langer, L | 1 |
| Säve-Söderbergh, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Ethnic Dependence of the Metabolic Defects in Prediabetic Individuals: Kuwaiti Arabs Versus Indians[NCT04268862] | 120 participants (Anticipated) | Observational | 2020-03-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for isoproterenol and Diabetes Mellitus
| Article | Year |
|---|---|
Magnesium ions and contraction of vascular smooth muscles: relationship to some vascular diseases.
Topics: Animals; Calcium; Diabetes Mellitus; Humans; Hypertension; Isoproterenol; Magnesium; Magnesium Defic | 1981 |
Studies on the mechanism of insulin action: basic concepts and clinical implications.
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Calcium; Cell Membrane; Cyc | 1977 |
1 trial available for isoproterenol and Diabetes Mellitus
| Article | Year |
|---|---|
Lisinopril and nifedipine administration inhibits the ex vivo uptake of [45Ca2+] by platelets from hypertensive diabetic patients.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Platelets; Bucladesine; Calcium; Diabet | 1992 |
43 other studies available for isoproterenol and Diabetes Mellitus
| Article | Year |
|---|---|
Topics: Adult; Angiotensin II; Animals; Athletic Performance; Blood Pressure; COVID-19; Diabetes Mellitus; H | 2022 |
Effects of Isoprenaline on ventricular myocyte shortening and Ca
Topics: Animals; Caffeine; Diabetes Mellitus; Diabetes Mellitus, Type 2; Isoproterenol; Myocytes, Cardiac; O | 2022 |
Two-hit mechanism of cardiac arrhythmias in diabetic hyperglycaemia: reduced repolarization reserve, neurohormonal stimulation, and heart failure exacerbate susceptibility.
Topics: Action Potentials; Angiotensin II; Animals; Arrhythmias, Cardiac; Blood Glucose; Calcium Signaling; | 2021 |
Sensitive determination of norepinephrine, synephrine, and isoproterenol by capillary electrophoresis with indirect electrochemiluminescence detection.
Topics: 2,2'-Dipyridyl; Body Fluids; Buffers; Diabetes Mellitus; Electrochemistry; Electrophoresis, Capillar | 2008 |
[Studies on a new type of antitussive combination preparation with special reference to diabetes].
Topics: Alcohols; Antitussive Agents; Diabetes Mellitus; Humans; Isoproterenol; Lung Diseases | 1962 |
SURGICAL TREATMENT OF COMPLETE HEART BLOCK. AN ANALYSIS OF 36 CASES.
Topics: Atropine; Chlorothiazide; Diabetes Mellitus; Ephedrine; Geriatrics; Heart Block; Heart Failure; Huma | 1964 |
No correlation between the p38 MAPK pathway and the contractile dysfunction in diabetic cardiomyocytes: hyperglycaemia-induced signalling and contractile function.
Topics: Animals; Antioxidants; Ascorbic Acid; Cells, Cultured; Diabetes Mellitus; Electrophysiology; Glucose | 2005 |
Cyclic nucleotides in diabetes mellitus and obesity.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Animals; Cyclic AMP; Cyclic GMP; Diabetes Melli | 1980 |
Responsiveness of plasma renin and aldosterone in diabetes mellitus.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Diabetes Mell | 1981 |
Insulin responses to nonglucose stimuli in non-insulin-dependent diabetes mellitus during a tolbutamide infusion.
Topics: Adult; Aged; Arginine; Blood Glucose; Diabetes Mellitus; Glucose; Humans; Insulin; Insulin Secretion | 1982 |
Improvement of defective insulin responses to glucose, arginine, and beta-adrenergic stimulation in diabetics by sodium salicylate.
Topics: Arginine; Cyclooxygenase Inhibitors; Diabetes Mellitus; Glucose; Humans; Insulin; Insulin Secretion; | 1980 |
Depression of leucine and isoproterenol induced insulin secretions in the spontaneously diabetic New Zealand white rabbit.
Topics: Animals; Diabetes Mellitus; Female; Glucose Tolerance Test; Insulin; Insulin Secretion; Isoprotereno | 1980 |
Isoproterenol-stimulated C-peptide and insulin secretion in diabetic and nonobese normal subjects: decreased hepatic extraction of endogenous insulin in diabetes.
Topics: Adult; Aged; C-Peptide; Diabetes Mellitus; Humans; Insulin; Insulin Secretion; Isoproterenol; Kineti | 1980 |
Blood glucose control and lipolysis in diabetes mellitus.
Topics: Adipose Tissue; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glycerol; Humans; Insul | 1980 |
A role for endogenous prostaglandins in defective glucose potentiation of nonglucose insulin secretagogues in diabetics.
Topics: Adult; Aged; Arginine; Aspirin; Blood Glucose; Diabetes Mellitus; Glucose; Humans; Insulin; Insulin | 1981 |
The effects of diabetes on beta-adrenoceptor mediated responsiveness of human and rat atria.
Topics: Adrenergic beta-Agonists; Aged; Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Female; | 1998 |
The putative role of the hormone-sensitive lipase gene in the pathogenesis of Type II diabetes mellitus and abdominal obesity.
Topics: Abdomen; Adipose Tissue; Adrenergic beta-Agonists; Aged; Alleles; Body Constitution; Diabetes Mellit | 1998 |
Substrate utilization and thermogenic responses to beta-adrenergic stimulation in obese subjects with NIDDM.
Topics: Adrenergic beta-Agonists; Blood Glucose; Body Composition; Body Temperature Regulation; Diabetes Mel | 1999 |
The effects of insulin and beta-adrenergic stimulation on glucose transport, glut 4 and PKB activation in the myocardium of lean and obese non-insulin dependent diabetes mellitus rats.
Topics: Adrenergic beta-Agonists; Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mell | 2001 |
Adenosine 3':5'-monophosphate and guanosine 3':5'-monophosphate: levels and cyclase activities in liver and adipose tissue from diabetic mice (db/db).
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Cell Membrane; Cyclic AMP; Cyclic GMP; Diabetes Mellitus | 1978 |
Catechol effect on the lysosomal enzymes in the adipose tissues of obese and obese-diabetic monkeys.
Topics: Acetylglucosaminidase; Adipose Tissue; Animals; beta-Galactosidase; Diabetes Mellitus; Glycoside Hyd | 1979 |
Accelerated turnover of blood glucose in pertussis-sensitized rats due to combined actions of endogenous insulin and adrenergic beta-stimulation.
Topics: Animals; Bicarbonates; Blood Glucose; Diabetes Mellitus; Epinephrine; Heart; Hypoglycemia; Insulin; | 1976 |
The control of fatty acid metabolism in adult diabetes.
Topics: Adipose Tissue; Adult; Cyclic AMP; Diabetes Mellitus; Drug Synergism; Epinephrine; Fatty Acids; Glyc | 1975 |
Alanine and glutamine synthesis and release from skeletal muscle. IV. beta-Adrenergic inhibition of amino acid release.
Topics: Alanine; Animals; Bucladesine; Cortisone; Diabetes Mellitus; Epinephrine; Glucagon; Glutamine; In Vi | 1976 |
Noncyclic AMP-mediated lipolytic effect of bovine and porcine diabetogenic proteins.
Topics: Adipose Tissue; Animals; Bucladesine; Cattle; Cyclic AMP; Diabetes Mellitus; Epinephrine; Glucagon; | 1976 |
Catecholamine receptor sensitivity and the regulation of lipolysis in adult diabetes.
Topics: Adipose Tissue; Cyclic AMP; Diabetes Mellitus; Epinephrine; Fatty Acids; Humans; Insulin; Isoprotere | 1976 |
Abnormalities in the adrenergic control and the rate of lipolysis in isolated human subcutaneous adipose tissue in diabetes mellitus.
Topics: Adipose Tissue; Cyclic AMP; Diabetes Mellitus; Glycerol; Humans; In Vitro Techniques; Isoproterenol; | 1976 |
Relationship between lipolysis, cyclic AMP, and fat-cell size in human adipose tissue during fasting and in diabetes mellitus.
Topics: Adipose Tissue; Adult; Cyclic AMP; Diabetes Mellitus; Diabetes Mellitus, Type 1; Fasting; Female; Hu | 1979 |
Relationship between lipolysis and calcium in epididymal adipose tissue of obese-hyperglycaemic mice.
Topics: Adenosine Triphosphate; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Bucladesine; Calcium; | 1979 |
Potentiation of insulin secretory responses by plasma glucose levels in man: evidence that hyperglycemia in diabetes compensates for imparied glucose potentiation.
Topics: Adult; Blood Glucose; Catecholamines; Diabetes Mellitus; Glucose; Humans; Hyperglycemia; Insulin; In | 1979 |
Peritoneal clearances in scleroderma and diabetes mellitus: effects of intraperitioneal isoproterenol.
Topics: Adult; Cell Membrane Permeability; Creatinine; Diabetes Mellitus; Female; Humans; Isoproterenol; Mid | 1976 |
Alterations in G-protein expression, Gi function and stimulatory receptor-mediated regulation of adipocyte adenylyl cyclase in a model of insulin-resistant diabetes with obesity.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Cell Membrane; Cells, Cultured; Colforsin; Diabetes Mell | 1992 |
[The effect of pharmacological agents on pancreatic incretory activity in patients with chronic pancreatitis].
Topics: Aminophylline; C-Peptide; Calcium Gluconate; Chronic Disease; Diabetes Mellitus; Glucagon; Gluconate | 1989 |
Visceral obesity and diabetes.
Topics: Adipose Tissue; Adult; Anthropometry; Blood Glucose; Diabetes Mellitus; Female; Glucose Tolerance Te | 1988 |
Enhanced adrenergic sensitivity of the diabetic neonatal heart.
Topics: Animals; Animals, Newborn; Coronary Circulation; Diabetes Mellitus; Dose-Response Relationship, Drug | 1985 |
An analysis of the lipolysis in vitro of obese-hyperglycaemic and diabetic mice.
Topics: Adenine Nucleotides; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Blood Glucose; Cyclic AMP | 1969 |
Adrenergic modification of glucose-induced biphasic insulin release from perifused rat pancreas.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-A | 1971 |
[Six years' experience with a musculoplastic technic].
Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists | 1971 |
Studies of immunoreactive insulin secretion in NZO mice in vivo.
Topics: Aminophylline; Animals; Antigens; Arginine; Diabetes Mellitus; Disease Models, Animal; Fasting; Gluc | 1974 |
The glucose receptor. A defective mechanism in diabetes mellitus distinct from the beta adrenergic receptor.
Topics: Blood Glucose; Diabetes Mellitus; Glucose; Humans; Insulin; Isoproterenol; Obesity; Propranolol; Rec | 1973 |
Insulin response to glucose, tolbutamide, secretin, and isoprenaline in maturity-onset diabetes mellitus.
Topics: Adult; Aged; Blood Glucose; Body Weight; Diabetes Mellitus; Female; Glucose; Humans; Injections, Int | 1972 |
Serum insulin following isoprenaline in normal and diabetic persons.
Topics: Adolescent; Adult; Aged; Antigens; Blood Glucose; Diabetes Mellitus; Glucose; Glucose Tolerance Test | 1972 |
Infrared thermography in diabetes mellitus. A preliminary study.
Topics: Adult; Diabetes Mellitus; Diabetic Angiopathies; Extremities; Female; Humans; Isoproterenol; Male; M | 1967 |