isoproterenol has been researched along with Constriction, Pathologic in 36 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Constriction, Pathologic: The condition of an anatomical structure's being constricted beyond normal dimensions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "001); (b) during an infusion of isoproterenol, paradoxic bradycardia occurred (delta R-R + 140." | 7.69 | Induction of paradoxic bradycardia in rats by inferior vena cava occlusion during the administration of isoproterenol: the essential role of augmented sympathetic tone. ( Asta, JA; Waxman, MB, 1997) |
| "Adenosine by inhalation causes bronchoconstriction in asthmatic but not in normal subjects by an undefined mechanism." | 7.67 | Adenosine-induced bronchoconstriction in asthma. Role of parasympathetic stimulation and adrenergic inhibition. ( Cushley, MJ; Holgate, ST; Mann, JS, 1985) |
| " Transgenic (TG) mice with cardiomyocyte-specific overexpression of mitofilin were generated, and cardiac hypertrophy was introduced by transverse aortic constriction (TAC) or chronic infusion of isoproterenol (ISO)." | 3.80 | Overexpression of mitofilin in the mouse heart promotes cardiac hypertrophy in response to hypertrophic stimuli. ( An, XZ; Chen, HZ; Li, H; Liu, DP; Liu, G; Luo, YX; Xu, J; Zhang, R; Zhang, Y, 2014) |
| "001); (b) during an infusion of isoproterenol, paradoxic bradycardia occurred (delta R-R + 140." | 3.69 | Induction of paradoxic bradycardia in rats by inferior vena cava occlusion during the administration of isoproterenol: the essential role of augmented sympathetic tone. ( Asta, JA; Waxman, MB, 1997) |
| "Adenosine by inhalation causes bronchoconstriction in asthmatic but not in normal subjects by an undefined mechanism." | 3.67 | Adenosine-induced bronchoconstriction in asthma. Role of parasympathetic stimulation and adrenergic inhibition. ( Cushley, MJ; Holgate, ST; Mann, JS, 1985) |
| "In an in vivo model of cardiac hypertrophy, expression of MITF and the BRG1 subunit of the SWI/SNF complex increased coordinately in response to pressure overload." | 1.42 | MITF interacts with the SWI/SNF subunit, BRG1, to promote GATA4 expression in cardiac hypertrophy. ( de la Serna, IL; Joe, B; Kumarasamy, S; Liu, L; Mehta, G; Walsh, A; Williams, K; Wu, J, 2015) |
| "The transition from compensated left ventricular hypertrophy (LVH) to heart failure is associated with alterations in the myocardial interstitium." | 1.31 | Reduction in myocardial collagen cross-linking parallels left ventricular dilatation in rat models of systolic chamber dysfunction. ( Chung, ES; Lancaster, EJ; Mela, T; Meyer, TE; Norton, GR; Sprott, S; Tsotetsi, OJ; Woodiwiss, AJ, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (61.11) | 18.7374 |
| 1990's | 5 (13.89) | 18.2507 |
| 2000's | 1 (2.78) | 29.6817 |
| 2010's | 6 (16.67) | 24.3611 |
| 2020's | 2 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Estrada, AC | 1 |
| Yoshida, K | 1 |
| Saucerman, JJ | 1 |
| Holmes, JW | 1 |
| Chen, Y | 1 |
| Pan, R | 1 |
| Zhang, J | 1 |
| Liang, T | 1 |
| Guo, J | 1 |
| Sun, T | 1 |
| Fu, X | 1 |
| Wang, L | 1 |
| Zhang, L | 1 |
| Voelkl, J | 1 |
| Alesutan, I | 1 |
| Pakladok, T | 1 |
| Viereck, R | 1 |
| Feger, M | 1 |
| Mia, S | 1 |
| Schönberger, T | 1 |
| Noegel, AA | 1 |
| Gawaz, M | 1 |
| Lang, F | 1 |
| Zhang, Y | 1 |
| Xu, J | 1 |
| Luo, YX | 1 |
| An, XZ | 1 |
| Zhang, R | 1 |
| Liu, G | 1 |
| Li, H | 1 |
| Chen, HZ | 1 |
| Liu, DP | 1 |
| Mehta, G | 1 |
| Kumarasamy, S | 1 |
| Wu, J | 1 |
| Walsh, A | 1 |
| Liu, L | 1 |
| Williams, K | 1 |
| Joe, B | 1 |
| de la Serna, IL | 1 |
| Liu, JJ | 1 |
| Zhao, CM | 1 |
| Li, ZG | 1 |
| Wang, YM | 1 |
| Miao, W | 1 |
| Wu, XJ | 1 |
| Wang, WJ | 1 |
| Liu, C | 1 |
| Wang, D | 1 |
| Wang, K | 1 |
| Li, L | 1 |
| Peng, LY | 1 |
| Koch, SE | 1 |
| Mann, A | 1 |
| Jones, S | 1 |
| Robbins, N | 1 |
| Alkhattabi, A | 1 |
| Worley, MC | 1 |
| Gao, X | 1 |
| Lasko-Roiniotis, VM | 1 |
| Karani, R | 1 |
| Fulford, L | 1 |
| Jiang, M | 1 |
| Nieman, M | 1 |
| Lorenz, JN | 1 |
| Rubinstein, J | 1 |
| Ha, YM | 1 |
| Ham, SA | 1 |
| Kim, YM | 1 |
| Lee, YS | 1 |
| Kim, HJ | 1 |
| Seo, HG | 1 |
| Lee, JH | 1 |
| Park, MK | 1 |
| Chang, KC | 1 |
| WHALEN, RE | 1 |
| COHEN, AI | 1 |
| SUMNER, RG | 1 |
| McINTOSH, HD | 1 |
| BRAUNWALD, E | 4 |
| EBERT, PA | 1 |
| HARRISON, DC | 1 |
| GLICK, G | 1 |
| MASON, DT | 1 |
| CHIDSEY, CA | 1 |
| ROSS, J | 2 |
| MARCUS, FI | 1 |
| WESTURA, EE | 1 |
| SUMMA, J | 1 |
| HERNANDEZ, RR | 1 |
| GREENFIELD, JC | 1 |
| MCCALL, BW | 1 |
| SOUZA, JE | 1 |
| DE MAGALHAES, HM | 1 |
| PORTUGAL, OP | 1 |
| CAMPOSFILHOCDE, M | 1 |
| MCLAUGHLIN, JS | 1 |
| MORROW, AG | 3 |
| BUCKLEY, MJ | 1 |
| PIERCE, GE | 1 |
| LAMBREW, CT | 1 |
| ROCKOFF, SD | 1 |
| WIGLE, ED | 1 |
| DAVID, PR | 1 |
| LABROOSE, CJ | 1 |
| MCMEEKAN, J | 1 |
| KLEIN, MD | 1 |
| LANE, FJ | 1 |
| GORLIN, R | 1 |
| FRYE, RL | 1 |
| KINCAID, OW | 1 |
| SWAN, HJ | 1 |
| KIRKLIN, JW | 1 |
| Hosokawa, T | 1 |
| Goto, K | 1 |
| Kamei, J | 1 |
| Ohtani, K | 1 |
| Misawa, M | 1 |
| Yanaura, S | 1 |
| Pandian, NG | 1 |
| Kieso, RA | 1 |
| Kerber, RE | 1 |
| Ely, SW | 1 |
| Sawyer, DC | 1 |
| Anderson, DL | 1 |
| Scott, JB | 1 |
| Waxman, MB | 1 |
| Asta, JA | 1 |
| Woodiwiss, AJ | 1 |
| Tsotetsi, OJ | 1 |
| Sprott, S | 1 |
| Lancaster, EJ | 1 |
| Mela, T | 1 |
| Chung, ES | 1 |
| Meyer, TE | 1 |
| Norton, GR | 1 |
| Svedmyr, N | 1 |
| Ilebekk, A | 1 |
| Thorvaldson, J | 1 |
| Kiil, F | 1 |
| Leone, BJ | 1 |
| Lehot, JJ | 1 |
| Dorrington, KL | 1 |
| Foëx, P | 1 |
| Battarbee, HD | 1 |
| Zavecz, JH | 1 |
| Gallagher, KP | 1 |
| Jongejan, RC | 1 |
| De Jongste, JC | 1 |
| Raatgeep, RC | 1 |
| Bonta, IL | 1 |
| Kerrebijn, KF | 1 |
| Murata, K | 1 |
| Mann, JS | 1 |
| Cushley, MJ | 1 |
| Holgate, ST | 1 |
| Fanta, CH | 1 |
| Watson, JW | 1 |
| Lacouture, PG | 1 |
| Drazen, JM | 1 |
| Todd, GL | 1 |
| Baroldi, G | 1 |
| Pieper, GM | 1 |
| Clayton, FC | 1 |
| Eliot, RS | 1 |
| Mue, S | 1 |
| Ishihara, T | 1 |
| Tamura, G | 1 |
| Hida, W | 1 |
| Sekizawa, K | 1 |
| Yamauchi, K | 1 |
| Takishima, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Metoprolol in Post Alcohol Septal Ablation Patients With Hypertrophic Cardiomyopathy[NCT04133532] | Phase 4 | 22 participants (Actual) | Interventional | 2020-03-05 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for isoproterenol and Constriction, Pathologic
| Article | Year |
|---|---|
Adrenergic stimulants and asthma mortality.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Asthma; Bronchi; Chloro | 1977 |
Transmural steal with isoproterenol and exercise in poststenotic myocardium.
Topics: Animals; Blood Flow Velocity; Constriction, Pathologic; Coronary Circulation; Coronary Vessels; Dogs | 1990 |
Experimental catecholamine-induced myocardial necrosis. I. Morphology, quantification and regional distribution of acute contraction band lesions.
Topics: Animals; Cardiomyopathies; Catecholamines; Constriction, Pathologic; Dogs; Hemodynamics; Isoproteren | 1985 |
33 other studies available for isoproterenol and Constriction, Pathologic
| Article | Year |
|---|---|
A multiscale model of cardiac concentric hypertrophy incorporating both mechanical and hormonal drivers of growth.
Topics: Biomechanical Phenomena; Cardiomegaly; Computer Simulation; Constriction, Pathologic; Hormones; Huma | 2021 |
Pinoresinol diglucoside (PDG) attenuates cardiac hypertrophy via AKT/mTOR/NF-κB signaling in pressure overload-induced rats.
Topics: Animals; Animals, Newborn; Aorta, Abdominal; Cardiomegaly; Constriction, Pathologic; Disease Models, | 2021 |
Annexin A7 deficiency potentiates cardiac NFAT activity promoting hypertrophic signaling.
Topics: Adrenergic beta-Agonists; Animals; Annexin A7; Aorta; Blotting, Western; Calcium-Binding Proteins; C | 2014 |
Overexpression of mitofilin in the mouse heart promotes cardiac hypertrophy in response to hypertrophic stimuli.
Topics: Animals; Cardiomegaly; Constriction, Pathologic; Heart; Humans; Isoproterenol; Male; Mice; Mice, Tra | 2014 |
MITF interacts with the SWI/SNF subunit, BRG1, to promote GATA4 expression in cardiac hypertrophy.
Topics: Angiotensin II; Animals; Aorta; Base Sequence; Binding Sites; Cardiomegaly; Cell Line; Constriction, | 2015 |
miR-218 Involvement in Cardiomyocyte Hypertrophy Is Likely through Targeting REST.
Topics: Animals; Cells, Cultured; Constriction, Pathologic; Disease Models, Animal; Down-Regulation; Gene Ex | 2016 |
Transient receptor potential vanilloid 2 function regulates cardiac hypertrophy via stretch-induced activation.
Topics: Adrenergic beta-Agonists; Angiotensin II; Animals; Aorta; Calcium Channels; Constriction, Pathologic | 2017 |
β₁-adrenergic receptor-mediated HO-1 induction, via PI3K and p38 MAPK, by isoproterenol in RAW 264.7 cells leads to inhibition of HMGB1 release in LPS-activated RAW 264.7 cells and increases in survival rate of CLP-induced septic mice.
Topics: Animals; Cecum; Cell Line; Constriction, Pathologic; Heme Oxygenase-1; HMGB1 Protein; I-kappa B Kina | 2011 |
Demonstration of the dynamic nature of idiopathic hypertrophic subaortic stenosis.
Topics: Aortic Valve Stenosis; Cardiomyopathy, Hypertrophic; Cardiomyopathy, Hypertrophic, Familial; Constri | 1963 |
Hemogynamic alterations in idiopathic hypertrophic subaortic stenosis induced by sympathomimetic drugs.
Topics: Aortic Valve Stenosis; Blood Circulation; Cardiomyopathy, Hypertrophic; Constriction, Pathologic; Hu | 1962 |
EFFECTS OF BETA ADRENERGIC BLOCKADE ON THE CIRCULATION WITH PARTICULAR REFERENCE TO OBSERVATIONS IN PATIENTS WITH HYPERTROPHIC SUBAORTIC STENOSIS.
Topics: Adolescent; Adrenergic beta-Antagonists; Aortic Valve Stenosis; Cardiac Catheterization; Child; Cons | 1964 |
THE HEMODYNAMIC EFFECT OF THE VALSALVA MANEUVER IN MUSCULAR STENOSIS.
Topics: Angiocardiography; Aortic Valve Stenosis; Blood Pressure; Brachial Artery; Cardiac Catheterization; | 1964 |
PRESSURE-FLOW STUDIES IN HYPERTROPHIC SUBAORTIC STENOSIS.
Topics: Aorta; Aorta, Thoracic; Aortic Valve Stenosis; Blood Circulation; Blood Flow Velocity; Cardiac Cathe | 1964 |
[COMPARATIVE STUDY OF THE ACTION OF ISUPREL ON THE DYNAMICS OF THE LEFT VENTRICLE IN AORTIC VALVULAR STENOSIS AND IDIOPATHIC HYPERTROPHIC SUBAORTIC STENOSIS].
Topics: Adolescent; Aortic Valve Stenosis; Blood Circulation; Blood Pressure; Blood Pressure Determination; | 1964 |
THE EXPERIMENTAL PRODUCTION OF HYPERTROPHIC SUBAORTIC STENOSIS.
Topics: Angiocardiography; Animals; Aortic Coarctation; Cardiac Catheterization; Cardiomyopathy, Hypertrophi | 1964 |
IDIOPATHIC HYPERTROPHIC SUBAORTIC STENOSIS. 3. INTRAOPERATIVE STUDIES OF THE MECHANISM OF OBSTRUCTION AND ITS HEMODYNAMIC CONSEQUENCES.
Topics: Adolescent; Aortic Valve Stenosis; Arrhythmias, Cardiac; Blood Flow Velocity; Blood Pressure; Blood | 1964 |
IDIOPATHIC HYPERTROPHIC SUBAORTIC STENOSIS. I. A DESCRIPTION OF THE DISEASE BASED UPON AN ANALYSIS OF 64 PATIENTS.
Topics: Adolescent; Amyl Nitrite; Angiocardiography; Aortic Valve Stenosis; Blood Pressure; Cardiac Catheter | 1964 |
MUSCULAR SUBAORTIC STENOSIS; THE INTERRELATION OF WALL TENSION, OUTFLOW TRACT "DISTENDING PRESSURE" AND ORIFICE RADIUS.
Topics: Amyl Nitrite; Angiotensins; Blood Pressure; Cardiac Catheterization; Cardiac Surgical Procedures; Ca | 1965 |
EFFECT OF LEFT VENTRICULAR SIZE AND SHAPE UPON THE HEMODYNAMICS OF SUBAORTIC STENOSIS.
Topics: Angiocardiography; Blood Pressure; Cardiac Catheterization; Cardiomyopathies; Cardiomyopathy, Hypert | 1965 |
RESULTS OF SURGICAL TREATMENT OF PATIENTS WITH DIFFUSE SUBVALVULAR AORTIC STENOSIS.
Topics: Adolescent; Aged; Angiocardiography; Aortic Stenosis, Subvalvular; Cardiac Surgical Procedures; Card | 1965 |
Analysis of the vagal reflex tracheal constriction in the dog.
Topics: Animals; Bronchi; Bronchial Spasm; Constriction, Pathologic; Dogs; Histamine; Isoproterenol; Pentoba | 1984 |
Two-dimensional echocardiography in experimental coronary stenosis. II. Relationship between systolic wall thinning and regional myocardial perfusion in severe coronary stenosis.
Topics: Animals; Constriction, Pathologic; Coronary Circulation; Coronary Disease; Dogs; Echocardiography; I | 1982 |
Carotid sinus reflex vasoconstriction in right coronary circulation of dog and pig.
Topics: Animals; Carotid Artery Diseases; Carotid Sinus; Constriction, Pathologic; Coronary Circulation; Dog | 1981 |
Induction of paradoxic bradycardia in rats by inferior vena cava occlusion during the administration of isoproterenol: the essential role of augmented sympathetic tone.
Topics: Animals; Blood Pressure; Bradycardia; Carotid Sinus; Constriction, Pathologic; Denervation; Heart Ra | 1997 |
Reduction in myocardial collagen cross-linking parallels left ventricular dilatation in rat models of systolic chamber dysfunction.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Abdominal; Body Weight; Captopril; Collage | 2001 |
Left ventricular function during acute elevation of aortic blood pressure in dogs.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Blood Volume; Cardiac Output; Constriction; Constric | 1976 |
Left ventricular regional function and relaxation: effects of inotropic stimulation.
Topics: Animals; Aorta, Thoracic; Aortic Diseases; Blood Pressure; Calcium Chloride; Cardiac Output; Cardiac | 1992 |
Cardiac performance in the portal vein-stenosed rat.
Topics: Animals; Constriction, Pathologic; Heart; Heart Rate; Isoproterenol; Male; Myocardial Contraction; P | 1992 |
Effects of changes in osmolarity on isolated human airways.
Topics: Adult; Aged; Aged, 80 and over; Bronchi; Calcium; Constriction, Pathologic; Female; Humans; Hyperton | 1990 |
Parotid gland recovery from an obstruction--changes of amylase release from the tissue.
Topics: Amylases; Animals; Constriction, Pathologic; Isoproterenol; Male; Parotid Diseases; Parotid Gland; R | 1986 |
Adenosine-induced bronchoconstriction in asthma. Role of parasympathetic stimulation and adrenergic inhibition.
Topics: Adenosine; Adult; Asthma; Bronchi; Bronchial Provocation Tests; Constriction, Pathologic; Female; Hi | 1985 |
In vivo bronchodilator activity of nifedipine in the guinea pig.
Topics: Airway Resistance; Animals; Bronchi; Bronchodilator Agents; Constriction, Pathologic; Dose-Response | 1987 |
The participation of the subepithelial airway receptor in the bronchoconstriction of monkeys.
Topics: Aerosols; Airway Resistance; Animals; Atropine; Bronchi; Constriction, Pathologic; Female; Histamine | 1985 |